Surgeon General's Office
/ 0%J4~2^
s Q-eoc
- ij\- ' ' .J ' -., y^
/
— aoo - >
4
V*
.*.
HOMEOPATHIC PROVINGS,
■
CONTAINING THE VIENNA PROVINGS OF
COLOCYNTII AND THUJA-OCCIDENTALIS,
AND THE SYMPTOMS OF
AETHUSA-CYNAPIUM,
ALCOHOL-SULPHURIS,
AMPHISB^ENA-VERMICULARIS,
ANAGALLIS-ARVENSIS,
APIS-MELLIFICA,
ARISTOLOCHIA-MILHOMENS,
ARSENICUM-METALLICUM,
ARTEMISIA-VULGARIS,
ASTERIAS-RUBENS,
CINNABARIS,
TURPETHUM,
COCCUS-CACTI.
BEING THE APPENDIX TO THE
NORTH AMERICAN HOMEOPATHIC JOURNAL.
EDITED BY
JAMES W. METCALF, M.D
NEW-YORK :
WILLIAM RADDE, 322 BROADWAY>
Philadelphia: Eademacuer & Sheek. — Boston: Otis Clapp. — St. Louis
C. P. Wesseliioeft. — Manchester : Turner. 91 Piccadilly.
1853.
\853
CONTENTS.
Thuja-accidentalis, 3
AeTHUSA-CYNAPIUM, 159
Alcohol-sulphuris, 167
Amphisbaena-vermicularis, 179
Anagallis-arvensis, 181
Apis-mellifica, ' 184
Aristolochia-milhomens, - - ' - 203.
Arsenecum-metallicdm, — 208
Artemisia- vulgaris, - - -- - - . - '- -222
Asterias-rubens, J - 223
ClNNABARIS, - - - V. - - - - - 229
MERCURIUS-SULPHURICUS OR TrJRPETHUM-MTNERALE, - - 281
COLOCTNTHIS, 283
COCCUS-CACTI, 387
HOMOEOPATHIC MEDICINES.
WILLIAM EADDE,
322 BROADWAY, NEW-YORK,
Respectfully informs the Homoeopathic Physicians, and the friends of the
System, that he is the sole Agent for
THE LEIPZIG CENTRAL HOMOEOPATHIC PHARMACY,
and that he has always on hand a good assortment of the best Homoeopathic
Medicines, in complete sets, or by single vials, in
TINCTURES, DILUTIONS, AND TRITURATIONS.
Also, Pocket Cases of Medicines ; Physicians' and Families'' Medicine
Chests to Laurie's Domestic (60 to 82 Remedies)— Epp's (60 Remedies)—
Hering's (60 Remedies to 102).
Small Pocket Cases at $3, with Family Guide, and 27 Remedies.
Cases containing 415 vials, with Tinctures and Triturations for Physi-
cians.
Cases with 268 Yials of Tinctures and Triturations to Jahrs New Manual,
or Symptomen-Codex.
Physicians' Pocket Cases, with 60 Vials of Tinctures and Triturations.
Cases from 200 to 300 Vials, with low and high dilutions of medicated
pellets.
Cases from 50 to 80 Vials of low and high dilutions, &c, &c.
Homoeopathic Chocolate.
Refined Sugar of Milk, pure Globules, &c.
Arnica Tincture, the best specific remedy for bruises, sprains, wounds, etc.
Arnica Plaster, the best application for Corns.
Arnica Salve, Urtica urens tincture and salve, and Dr. Reisig's Homoeopa-
thic Pain Extractor, are the best remedies for Burns.
Canchalagua, a specific in Fever and Ague.
ALSO,
BOOKS, PAMPHLETS, AND STANDARD WORKS ON THE SYSTEM
IN THE ENGLISH, FRENCH, SPANISH, AND GERMAN LANGUAGES.
23IP Physicians ordering medicines will please mark after each one its
strength and preparation, as :
moth, tinct, for mother tincture.
1. frit, or 3. trit. for first or third trituration.
6. in liq. or 30. in liq. for six or thirtieth attenuation in liquid.
3. in glob, or 30. in glob, for third or thirtieth attenuation in globules.
d)ttja ©aitontttli*-
The following exhausting proving of TJiuja Occidentalis
is translated from the Oesterreichische Zeitschrift, Band 2,
s. 289 et seaa : — a part of it has already appeared fragmenta-
rily in the Homoeopathic Examiner ', volume 5, page 159, &c.
It is here reproduced entire, with corrections, that it may be
more conveniently studied and referred to by students of the
Materia Medica and the Profession.
EDS. NORTH AM. HOM. JOURNAL.
CONTENTS,
Chaf - Page.
I. Etymology, synonymes, description and chemical con-
stituents of Thuja, 3
II. Anti-Hahnemnannian notions of the medicinal virtues of
Thuja, ...... 6
111.^1. Proving of Hahnemann, .... 7
2. " Franz, .... 13
3. " Gross, . . . . .13
4. " F. Hahnemann, . . . 14
5. " Haynel, . . . . .14
6. " Hartmann, . . . . 14
7. " Hempel, . . . . .15
8. " Langhammer, . . . 15
9. 10. " Teuthorn and Wagner, . . .16
11. " Wislicenus, . . . . 17
IV. Results of our own provings of Thuja on the healthy
organism, . . . . . .18
12, 13. Provings of Bohm, .... 18
14-21. " Frolich, . . . .20
22-24. " Huber, .... 26
25-31. " W. Huber, . . ^_ -^ 33
32. " F. Lackner/,' ^fc j^ ^ 39
33, 34. " Landesmann, . . >\ . 43
35. " Liedbeck, . JciJ 45
36, 37. " Maschauer, . -_. ^0 / L 46
38-42. " Mayrhofer, . . .J + 49
43-45. " Reisinger, . . . .55
46, 47. " Sterz, .... 57
CONTENTS.
Chap. Page-
48, 49. Provings of Wachtel, . . . .58
50-54. " Watzke, .... 62
55-59. " Wurmb, . . . . 66
60-63. " Zeiner, 70
64-67. " Von Zlatarovich, . . .75
68. " Zoth, . . . . • 98
69. " Zwerina, . . • .100
10-19. " Holleczeck, . . .101
V. Symptomatology and characteristics of the Thuja-sickness, 108
VI. Therapeutics of Thuja, . . . . .121
A. Diseases of the urinary and sexual organs, . 122
a. Blenorrhceas, . . . . .122
b. Diseases of the prostate gland, . . 124
c. Condylomata, . ■ . . .125
1. Uncomplicated sycosis, . . . 131
2. Sycosis with rhagades, . . .134
3. Sycosis coexistent with syphilis, . . 135
4. Sycosis after the cure of syphilis, . .136
5. Masked sycosis, . . . . 137
6. Chancre warts, . . • .140
B. Verrucae, Warts, .... 141
C. Swellings and excrescences on the eyelids, . .143
D. Pains in the limbs, . . . .144
E. Intermittent fever, . . . . .145
■ F. Cures in cases of animals, . . . 146
VII. Essay towards a theory of the operation of Thuja, . 147
VIII. Dose, duration of action, allied remedies, and antidote, 148
Appendix. Are gonorrhoea and chancre results of the same
disease ? . . . . . . 151
THUJA OCCIDENTALIS.
AN ESSAY.
BY CARL MAYRHOFER, M. D.
CHAPTER I.
Etymology, synonymes, description and chemical constitu-
tion of Thuja.
The term " arbor vitce," has a threefold acceptation in literature ;
pharmacological, botanical, and anatomical.
Van Helmont wrote a special treatise entitled " arbor vitce," by
which he understood a macrobiotic mixture, among the ingredients of
which the wood and resin of the cedar hold the principal rank. It was
supposed that life was prolonged by the continued use of this drug ;
that it was a prophylactic against every disease, and that it gave
strength to patients ; it was looked upon as a sort of elixir of life, such
as are found in abundance in the older books on medicine, evidences of
the mystic faith of those times, and such as are sold even now to the
credulous public for their weight in gold.
Every physician knows what is meant by " arbor vita?" anatomically.
On making a deep longitudinal cut through the lobes of the cerebellum,
the substance of the brain presents the appearance of a tree, called by
the anatomists arbor vitce, because the cerebellum was supposed to be
the principal seat of life.
The subject of our essay is, however, a real tree, the western arbor
vitce or Thuja occidentalis. In the time of Francis I., king of France,
this tree was imported into France from Canada. The first specimen
was seen by Clusius in the royal garden of Fontainebleau, and a tolera-
bly correct figure and description of it were furnished by him under
the name of arbor vitce* The Greek name $va also &veia or $via
from dvecv, suffire, to fumigate, points to a resinous tree, and is first
seen in Theophrastus Lesbius, a disciple of Aristotle ; in his work,
" tteqi (f>VTO)v loropiag" he describes a tree resembling the cypress
and called $vov (devdpov) or dva (Idea, species). Roman authors
latinized the word dva, changing it to Thya, Thuya, Thuia, Thuja, as
#uc gen. dveog, was changed to thus, gen. thuris, and the word
nviraQiooog- to cupressus. We have adopted in this essay the spel-
ling Thuja, which is most frequently used and is most correct.
* Caroli Clusii Rarior. Plantar. Histor., 1601.
A
4 Thuja Occidentalis.
In the copious synonymes of Thuja, there seems to be some con-
fusion. According to Theophrastus, the precious carvings in the
temples of the ancient Greeks were made of the indestructible wood
of the dva. In his Natural History,* Pliny quotes Theophrastus,
with the remark that the tree which was called by the Greeks tivov or
3va was known to Homer. Clusius says (loc. cit.) : " Ad quam arborem
veteribus descriptam referenda sit {arbor vita;), non facile quis conji-
ciat," adding that it was generally believed that the arbor vitse is the
■&va of Theophrastus. Bauhinius calls the arbor vitas Thuja Thco-
phrasti, and even in our own time the belief is entertained by some
that the Thuja Theophrasti is our Thuja.
We do not accede to this opinion. The native region and habitat of
the Thuja of Theophrastus, according to his account, is the territory of
Cyrene, in Africa, and especially the region in which the temple of
Jupiter Ammon was situated, whereas our Thuja is a native of North
America and Siberia, and could not, therefore, have been known to the
ancients.
Our own inquiries have led us to assume that the Thuja of Theo-
phrastus is the Thuja articulata of Vahl, who has shown to a certainty
that it is from the Thuja, articulata that we obtain sandarac, and not,
as has been falsely believed heretofore, from a species of juniper. Shaw
described the tree as a species of cypress, but in the Flora Atlantica by
Desfontaines it is considered as a species of Thuja ; and recently we
have accurately ascertained by the French expedition to Algiers and
Morocco, that sandarac (el grassa), of which Morocco furnishes from
600-700 hundred weight, is derived from the Thuja articulata, which
the French botanists found throughout the territory of Algiers, and
Avhich probably likewise exists in Tunis and Tripoli, the ancient Cy-
rene, whence the ancients also may have derived it.
The terms " arbor vita;, arbor paradisea, arbre de vie, tree of life,"
are derived from the French, who first cultivated it. Clusius thinks
that the term arbor vita; arose from the perennial verdure of the tree,
immortalis coma, and from its strong and reputed healthy odor, and
that it was afterwards adopted by all subsequent writers.f Dioscorides
calls our Thuja Cedrus major ; Bellonius, Sabina altera ; Targione,
Cupressus arbor vita? ; Camerarius calls it simply Thuja, and Monch,
Thuja obtusa. Linna3us finally gave it the name of Thuja occidentalis,
in contradistinction from the Eastern Thuja, Thuja orientalis, which
was brought to Europe from northern China.
The Thuja occidentalis, which is found in the West Indies, in the
United States of North America and in Canada, belongs, according to
* Hist. Nat., lib. xiii, cap. xvi.
t We take this opportunity of observing that the symptoms which the probers
of Thuja experienced, by no means reminded them of the golden fruits of Paradise •
the consciousness, however, of something paradisaical in the sacrifice of his own
health at the shrine of science and humanity, that by that means the health of
others may be preserved, sustains the prover in the midst of the ingratitude of the
indifferent and the contumely of opponents. — Mayrhofer.
Description and Chemical Constitution. 5
the natural system of plants, to the family of the Coniferce Strobilacece,
and more particularly to the variety " cypress ;" according to Linnaeus'
sexual system it belongs to the class Monoecia. The common Thuja
attains a height of from thirty to forty feet ; its branches spread hori-
zontally in the shape of a fan ; the twigs are broad and flat ; the scales
of the leaves are placed over one another in four rows like the tiles of a
roof ; each scale is provided with a gland in the middle of the upper
surface, from which the Thuja-oil is secreted. The little cones are
egg-shaped, and contain winged seeds which, like all the varieties
of Thuja, Cypress and Juniper, are provided with two cotyledons ; this
distinguishes them from the varieties of pine which are of the class
'polycotyledonece. On pressing out the oil from the glands by rubbing
the twigs, they emit a strong odor, and their beautiful green changes in
winter by the alteration of the chlorophyll into a reddish brown which
is dark in proportion to the coldness of the season.
The native regions of the Thuja are North America and Siberia.
In Germany it is frequently used as an ornament in parks, and is fre-
quently cut into all sorts of stiff shapes according to the French taste.
Iu Upper Austria single Thujas are frequently found on farms, like the
Sabina, and are called Cedars. The Thuja orientalis is distinguished
from the Thuja occidentalis by its erect branches, the furrowed scales
of its leaves, its unwinged seeds, and the absence of the peculiar odor.*
Constituents of the Thuja occidentalis. — Besides the ordinary con-
stituents which are found in every plant, the Thuja contains, like most
coniferae, an ethereal oil of a strong odor, and a resin, its usual attend-
ant.
The ethereal oil, which exists in a lesser quantity in the Thuja than
might have been expected from its strong smell, is obtained by distilling
* Thuja Occidentalis. Common arbor vitce. Branchlets two-edged, spread-
ing ; leaves imbricated in four rows, ovate-rhomboid, closely compressed, with a small
flattened gland on the back ; cones nodding, obovoid, the scales few (5-7), inferior
ones truncate, gibbous at the tip ; seed compressed, winged all round. Linn. sp.
2, p. 1002 ; Mickx. fl. 2, p. 226 ; Pursh.fl. 2, p. 646 ; Michx. Sylv. 2, p. 156 ;
Ell. sk. 2, p. 644; Bigel.fl. Bost. p. 361 ; Beck, bot. p. 338; Hook,fl. Bor.-Am.
2, p. 165 ; Loud. Enc. tr. $ shr., p. 1068.
A tree with a narrowly conical and tapering head, [in New York] seldom
more than 30-35 feet high and 6-12 inches in diameter, much branched ; the
ultimate divisions flattened and covered with numerous obtuse shining leaves, each
furnished with a little vesicle which (as in the white Cedar) is filled with a thin
aromatic turpentine. Sterile aments minute at the extremity of the branchlets,
consisting of a few concave, scale-like anthers. Cones about five lines long, yel-
lowish-brown ; the scales loosely imbricated, opening to the base. Seeds conspicu-
ously winged, emarginate, one under each scale.
Rocky banks of rivers and hill-sides, also in swamps ; abundant and very con-
spicuous on the Hudson above Newburgh ; Oriskany swamp ; and various parts
of the northern and western counties [of the State of New York]. Fl. May.
The wood is light, of a reddish color and though soft, is very durable. It is not
much used for lumber, as its trunk does not afford pieces of sufficient length. It
is often planted about nouses and in pleasure-grounds. In some parts of the coun-
try it is called White Cedar, and in New England it is often called Hackmatack. —
Torrey, Fl. State N. Y.
6 Thuja Occidentalis.
the branches with water. It has been recently examined and analyzed by
Schweizer with great care. It is a mixture of at least two kinds of oil
containing oxygen. It does not contain any carburetted hydrogen.*
When freshly prepared it is entirely colorless, but it soon becomes
yellowish. It occasions the peculiar odor of Thuja and possesses an
acrid taste. It is lighter than water, is but sparingly soluble in that
liquid, but dissolves readily in alcohol and ether.
The anhydrous oil, the water having been removed in two different
ways by chloride of calcium, was found to contain :
Carbon 77,99 77,25.
Hydrogen 10,73 11,11.
Oxygen 11.28 11,64.
CHAPTER II.
Ante-Hahnemannian notions of the medicinal virtues of
Thuja.
The medicinal powers of Thuja were first brought from the regions
of faith into those of knowledge by Hahnemann : it is he who, by
means of physiological proving?, has given us the golden key to all the
treasures of nature in her medicinal preparations.
He saysf — " Before me no serious medicinal use Avas ever made of
this plant in Europe ; the remarks of Parkinson and Hermann about
the virtues of Thuja are mere theoretical conjecture, after the fashion of
their beloved Therapia generalis.
Clusius says (1. c.) : " JVon duhium est, quin ad pleraque sit utilis
(arbor vitai) ; nemo vero illius facilitates nostra avo prodidit. Cum
tamcn magnum ftabeat partium tenuitatem, et amariuscula sit, verosi-
mile est digerendi et abstergendi facilitate proditam esse.''''
We must excuse the age of Clusius for the breakneck conclusion, that
Thuja must have a dissolvent and a detergent power because it is a
fine and bitter plant.
Tabernsemontanus, dutiful disciple of Galen as he is, declares as fol-
lows : " The taste and odor of Thuja show that it must be of a warm
and dry nature ; but we do not yet know what it is good for."
CamerariusJ expresses himself in a similar manner : " This tree
ought not to be lightly esteemed, not only on account of its strong-
smell, but also on account of its other virtues. A water and an oil
may be prepared from it, which are said to be an excellent remedy
against gouty pains, if properly used."
* The presence of oxygen distinguishes the oil of Thuja from the oil of Sabina
and from turpentine, these two latter oils being free from oxygen and having an
analogous composition. C ln II 16 .
tRein. Aran. M. L., 2 Anfl. B. 5, s. 123.
iHort, p. 186.
Notions of Thuja anterior to Hahnemann. 7
In the Cynosura Materice Medico? Pauli Herrmanni, which was
continued by Bocclerus (editio II., Argentorati, 1*747, p. 565) the fol-
lowing virtues are ascribeed to Thuja : " Folia (thujce) resolvunt, ex-
siccant, flatus pellunt, et sudorem dent. Parkinsonus folia tenera et
cruda cum butyro pani illito comesta ad tenaces et viscidos humores
expectorandos nonnullis in usu esse scribit."
Krunitz (Encyklop. B. 66) gives the following extended version of
this passage (probably from the first edition of Herrmann's Cynosura) :
" The leaves disperse, dry, expel flatulence, and bring out sweat. The
wood is cleansing, it is good for the head, excites sweat, resists poison,
and is good in infirmities of the eyes and ears, either in the shape of
a powder or decoction."
Krunitz must have been staggered by the unbounded praise which
Herrmann bestows upon Thuja, for he adds : " I dare not relate all the
marvellous things which Herrmann tells of Thuja."
According to Boerhaave the water which has been distilled from
the branches of Thuja is useful in swellings ; according to others, a
decoction of the cones is useful in fever and ague.
According to Halm, the natives of America prepare an ointment
from the crushed leaves, and rub the limbs with it when they are affected
with pain.
These few quotations, which ' might be increased, are sufficient to
show, that, previous to Hahnemann, scarce anything was known of
the curative virtues of Thuja, and that the supposed remedial proper-
ties above mentioned were merely hypothetical notions.
The Thuja occidentalis has never been used as an officinal drug by the
physicians of the Old School, nor is it mentioned in the common
works on pharmacology, not even in Vogt's pharmacodynamics.
It is therefore the original and exclusive property of the new school,
a pearl of price for which we are indebted to Hahnemann.
CHAPTER III.
(1.) Hahnemann *s Proving of the Aebor vit^e
on the healthy.
The great medical reformer proved Thuja on himself and on ten of
his pupils. He gives us 330 symptoms,* which he had observed
partly on himself and partly on others among his immediate followers,
and some of which he had gathered from the sick. He had no assist-
ance from previous authors, as there was nothing known of the action
of -Thuja before his time, and he conducted its proving with zeal and
perseverance. The symptoms collected by him present the character-
istic features of Thuja in the clearest manner.
We give below the results of Hahnemann's proving, with the omis-
sion of the characterless, bracketed symptoms, and of those obtained
* R. A. M. L., 2 Aufl., B. 5, S. 125.
8 Thuja Occidentalis.
from the sick, and for greater convenience of inspection, take the liberty
of changing the anatomical order, of which Hahnemann was so fond,
for one founded on an anatomico-physiological basis.
General.
Sticking, tearing, and drawing in different parts of the body, parti-
cularly in the limbs ; itching, as from fieabites, on the body and limbs ;
pricking itching over the whole body ; crawling itching over the
whole body ; burning of the itching spots after having been rubbed ;
limbs go to sleep ; cracking in the joints on stretching the limbs ; ag-
gravation of the symptoms in the afternoon and night.
Skin.
Painful sensitiveness of the skin over the whole body ; inflamed
eruptions and tubercles on various places ; red, painful tubercles on the
temples; white tubercles of the size of a hazelnut on the calf, which
itch violently and for some distance around, and burn after being rub-
bed ; isolated pimples, like chickenpox, with a red areola and pus at
the summit, on the thighs, elbows and forearms ; pimples on the
knees, like smallpox, which itch and suppurate ; an itching boil on
the small of the back ; a red mottled spot on the dorsum of the left
foot and on the left forearm ; eruptions on the left buttock, which
itch and burn after having been scratched.
r
Sleep.
Early sleepiness ; late going to sleep ; restlessness before going to
sleep ; restless sleep ; restless tossing during sleep ; sleeplessness ; cry-
ing out in sleep ; talking in sleep ; anxious dreams, with loud excla-
mations ; weeping when asleep ; dreams of the dead, voluptuous
dreams.
Fever.
Chilliness, without thirst ; chills only on the left side in the even-
ing in bed ; chilliness every morning or every evening ; chills for five
hours, with thrice vomiting ; violent chill for a quarter of an hour at
about three o'clock, followed by thirst and sweat over the whole body,
except the head ; chilliness, with external heat of the body ; chilliness
in the back, with numbness in the fingers ; coldness of the body, with
great restlessness ; coldness of both legs, which are covered with cold
sweat.
Dry heat at night ; heat in the face, with burning and redness of
the cheeks ; violent ebullition of blood every evening, with throbbing
and beating in every vein ; redness and burning of the left cheek ■
heat, with sweat, towards morning; dry mouth, with thirst.
Hahnemann's Proving. 9
Mental and Moral.
_ Activity of the mind, with weakness of the body ; inability to rid
himself of the thoughts that occupy his mind ; unfitness for thinking,
with confusion in the head ; slowness of thought and speech.
Anxiety ; restless moral state ; vexation and depression ; tired of
life ; discontent ; great anxiety about trifles ; anxiety and solicitude
about the future.
Head and Face.
Vertigo when seated ; when lying ; reeling vertigo, with tottering
when walking ; headache in the forehead in the morning ; drawing,
sticking, pressing, boring headache ; sensation in the vertex, as if a
nail were driven into it with a sudden blow ; tearing in the right side
of the sinciput and face to the zygoma, morning and evening ; fine
prickling crawling in the head; itching of the occiput.
Drawing in the temporal muscles, worse when chewing ; prickling
pain in the temples ; craivling and filliping in the zygomata ; twitch-
ing in the buccinatores ; an itching, scurfy eruption on the corner of
the mouth.
PERCEPTIVE FACULTIES.
Visual Organs.
Eyes. — Sticking, pressing in the eyes ; redness and inflammation of
the sclerotica, with biting and pressing in the eye as if from sand ;
burning pressing in the external canthus of the left eye ; pressing in the
eyes, with the feeling as if they were protruded from their sockets ; single,
piercing stitches in the right inner canthus ; lachrymation of the left
eye ; secretion of gum in the inner canthi.
Eyelids. — A red tubercle on the edge of the lower eyelid.
Sight. — Shortsightedness ; dim sight, with the feeling as though
the eyelids were swollen ; sensation as if looking through gauze at
near objects, as well as at distant ones ; darker appearance of objects
around, when reading ; weak, obscure vision.
Auditory Organs.
Hammering and tearing in the ear until midnight ; forcing and con-
striction in the ear, and afterward a sudden, violent stitch there ; press-
ing in the meatus.
Olfactory Organs.
Daily epistaxis ; nasal mucus mixed with coagulated blood ; crawl-
ing in the nose as though from a cold ; feeling as of coryza, with stuffed
nose ; violent, rapidly appearing coryza ; profuse running at the nose,
with catarrh ; coryza, with nocturnal cough ; an ulcerous scab in the
nose.
10 Thuja Occidentalis.
Gustatory Organs.
Lips. — Twitching in the upper lip ; burning in the red part of the
lip and in the palate.
Tongue. — Sore pain on the tip of the tongue, when touching it ;
raw, scratching feeling on the tongue, with a white fur ; great swelling
of the tongue ; a white vesicle on the root of the tongue ; a white,
painful blister on the middle of the tongue.
Palate. — Burning in the palate ; sore pain in the whole palate
when swallowing ; feeling as if the oral cavity were full of blisters or
scorched ; pressing like weight in the velum palati.
Jaw and Teeth. — Sticking in the underjaw : sticking, drawing or
twitching toothache, especially early in the morning and in the evening ;
toothache, as though the nerve were touched.
Gums. — Great swelling of the gums ; swollen, sore gums.
Tonsils and Salivary Glands. — Swelling of the tonsils ; sticking
in the throat ; rough, scraped throat; copious flow of saliva ; saliva
mixed with blood.
Appetite and Taste. — Flat, sweetish taste ; appetite without relish
for food ; slimy taste (after eating) ; food tastes too little salted.
Respiratory Organs.
Trachea. — Sticking in the trachea ; hoarseness as though from con-
striction in the pharynx.
Lungs. — Difficult, embarrassed breathing with thirst and anxiety ;
constriction of the left breast which provokes a slight cough ; night-
cough ; oppression of the chest as though something had swollen there ;
constriction, forcing him to breathe deeply.
Heart. — Visible palpitation ; pain in the cardiac region ; violent
palpitation on going up stairs ; feeling of anxiety in the scrobiculus
cordis.
Thorax. — Pressing on the chest after eating ; paroxysms of pressure
on the chest in the region of the axilla ; feeling as if the chest were
inflated from within ; blue coloration of the skin on the clavicles.
Digestive Organs.
Pharynx. — Inclination to swallow ; pressing behind in the throat
when swallowing, feeling as though the pharynx were constricted and
swallowing obstructed by mucus.
Stomach. — Cramp in the stomach, becoming worse in the evening ;
rancid, foul eructations ; inflation and eructations as if from disordered
stomach ; heartburn.
Abdomen. — Pressing in the scrobiculus immediately after eating ;
constriction in the epigastric region ; tension in the abdomen ; inflated
hypogastrium ; pressure as from fulness in the right side of the abdo-
men ; rumbling in the abdomen ; jerking tearing in the abdomen ;
movement in the abdomen, as of something alive.
Hahnemann's Proving. 11
Faces. — Diminished evacuations ; ineffectual desire for stool ; de-
sire for stool with erection ; violent pain in the rectum during stool ;
painful constriction of the anus during stool ; diarrhceic stool.
Anus. — Burning at the anus ; violent burning in the furrow be.
tween the buttocks when walking ; burning sticking in the rectum
when not at stool.
Urinary Organs.
Urethra. — Burning in* the urethra especially when urinating and
also afterwards, and even without passing water ; cutting pain
when urinating ; biting and itching in the (female) urethra when
urinating ; flow of mucus from the female urethra ; a very violent
stitch from the rectum through the urethra ; stitches in the urethra
from behind forwards (when not urinating), stitches in the urethra
with stiffness of the penis ; tearing stitches in the anterior part of the
urethra ; twitching- cutting sticking in the urethra (when not urinat-
ing) ; feeling in the urethra as if moisture were oozing along it.
Urine. — Frequent urination; reddish urine ; pressing when urin-
ating with jerking ejection of the urine ; frequently interrupted stream ;
after urinating, a feeling as if a few drops were still passing on ;
after urinating, a little urine continues to flow in drops.
Sexual Organs.
Male. — Sticking and itching in the glans ; burning sticking in
the end of the glans when urinating ; single stitches in the end of
the glans when not urinating ; sticking itching on the side of the
glans; a roundish, flat, foul ulcer with a red border and burning
pain on the corona glandis ; behind the glans, red, smooth excres-
cences in which there is formication ; on the glans a small, low
vesicle which is painful when urinating ; moisture of the glans ;
balanorrhcea.
Painful stitches on the inner side of the prepuce ; great swelling
of the prepuce ; on the external surface of the prepuce, a red, ashy,
elevated spot, which passes into an ulcer with a scab, itches and
burns ; small pustules on the inner surface of the prepuce which
are depressed in the middle, are moist and suppurating ; a red ex-
crescence on the interior of the prepuce like a condyloma.
Fine stitches in the scrotum ; itching of the scrotum ; sweat on
the scrotum ; profuse sweat on the genitals ; scratching and itching
on the scrotum, with burning if the places are rubbed ; a moist
pimple on the scrotum ; drawing in the testicle; retraciion of the left
testicle towards the inguinal ring ; long-continued erection ; noc-
turnal erections.
Female. — Biting and itching in the female organs; sore pain
in the female parts, especially during urination ; swelling of both
labia which burn when walking and on being touched ; biting and
12 Thuja Occidentalis.
burning in the vagina when sitting and walking ; pressing and con-
striction in the genital organs ; constrictive pain in the genital organs
and perinaeum.
Glands.
Swelling of the salivary glands, with increased flow of saliva ;
swelling of the tonsils ; swelling of glands in the left cheek ; pain
in the swollen glands of the neck ; drawing pain in the groin when
standing and walking; drawing from the inguinal glands outwards
through the thigh into the knee ; stitches from the groin through the
thigh when sitting down ; painless swelling in the groin.
Spinal Column.
Nape. — Pain in the left side of the neck, as if from an uncomforta-
ble bed or position in lying ; swelling and blue coloration of the cervi-
cal veins ; alternate contraction and relaxation in the cervical muscles
and in the nape.
Back. — Drawing pain in the back when sitting ; pressing in small
spots on the back when sitting ; boring in a small spot in the back ;
sore pain in the back ; tearing in the left scapula ; crushing pain below
the shoulder-blade ; twitching over the upper part of the body.
Small of the back. — Tension ; drawing ; crushing pain after standing
up, more violent when standing and turning the trunk, less painful
when walking.
Extremities.
Upper. — Beating and throbbing in the shoulder-joint ; cracking of
the shoulder-joint when bending the arm backwards ; formicating-itch-
ing on the upper arm, and a fine stitch afterwards in a small spot ; feel-
ing of heaviness from the middle of the left upper arm to the fingers ;
raging pain in both arms from three, A. m., until six ; involuntary
twitching of the arm ; drawing in the arm of several hours' duration,
feeling as though it were in the bones ; digging-drawing pain in the
whole arm as if in the periosteum with the sensation, on deep pressure,
as if the flesh were loose from the bone ; pain in the humerus on pres-
sure ; painful difficulty of movement in both arms ; beating and throb-
bing in the elbow-joint, and in the evening drawing in the arms down
to the fingers ; tearing in the left wrist ; pain as of dislocation in the
right wrist ; fine sticking in the fingers ; fine prickling pain in the first
joints of the fingers ; fine sticking in the ends of the three left middle
fingers ; redness and swelling of the balls of both indices ; the anterior
joints of the three left middle fingers become red and swollen with fine
sticking down to the ends ; sweat on the hands.
Lower. — Tension from the hip-joint to the groin and in the posterior
part of the thigh to the popliteal space ; sticking in the most upper
part of the thigh ; the leg and thigh go to sleep when sitting ; sioeat
Provings of Hahnemann' 's Assistants. 13
of the thigh near the genitals ; crushing pain over the middle of both
thighs when walking ; cracking in the elbow, knee and ankle-joints
when stretching the limbs ; paroxysms of weariness in the thighs ; sin-
gle stitches in the knees when rising up and beginning to walk ; heavi-
ness and stiffness of the leg when walking ; drawing pain jerking
downwards in the right leg as if from weariness ; pressing in the tibia ;
inflammation, redness and swelling of the dorsum of the foot and of
the toes which are painful and tensive when treading on or moving
them ; involuntary upward twitching of the foot as the pain in-
creases ; pain in the heel as though it were asleep ; a sharp stitch in
the tendo Achillis (after 2 h.) ; drawing in all the toes ; drawing in
the great toe ; tearing stitches on both sides in the nails of the great
toes ; shining redness and swelling of the toes which itch and burn
after being rubbed ; sweat on the toes and feet proceeding upwards
over the legs and thighs to the head and thence to the scrobiculus,
with nausea.
The contributions of the pupils of Hahnemann follow in the alpha-
betical order of their names :
(2.) Franz.
Cloudiness of the head ; pressing in the left parietal bone (after 2 h.) ;
drawing in the left parietal bone (after 4 h.) ; sensation as if a nail
were driven into the right parietal bone {disappearing on touching it) ;
pressing drawing in the left temple ; occipital headache ; black points
before the eyes, which move about among each other, and are present
even when the eyes are closed ; itching in the face ; cramp pain in the
ear (after 4^ h.) ; rancid smell in the throat ; pressing in the right
groin (after 4 h.) ; formicating sticking in the right side of the chest
(after 3 h.) ; painful sticking in the right shoulder (after 5 h.) ; aching
in the small of the back when bowing ; painful sticking in the right
shoulder, opposite the clavicle (after 5 h.) ; pain, as of excoriation, on
the forearm and inner side of the thigh ; sensation in the knee as if it
were cut into with a sharp knife ; cutting pain in the left ankle when
walking ; drawing in the right great toe ; warmth over the whole body,
with cold fingers, especially on the left hand, without thirst (evening,
after 3 J h.) ; creeping chilliness, with icy cold hand, after gentle heat
(evening) ; heat, with thirst, without chilliness, with pleasant state of
mind.
Dr. Franz seems to have had but little sensibility to the action of
Thuja, or to have experimented with too small doses ; for, in the fore-
going picture, the image of the drug is but faintly distinguishable.
(3.) Gross.
A spot is painful on the occiput, when lying on his left side, the hairs
on which are sensitive to the touch ; luuvking up of bloody mucus
from the throat ; want of appetite ; flatulence, with inflated abdomen
14 . Thuja Occidentalis.
(after a meal) ; weakness and weariness, with nausea, which compel
him to lie down ; frequent passage of pappy stools ; evacuation of hard
faeces in balls, which are streaked with blood* (after 14 h.) ; frequent
passing of copious clear urine, watery ; red urine, which deposits a la-
teritious sediment on standing ; epistaxis ; blowing of blood from the
nose ; intermitting stitches in the chest ; warm perspiration on the
covered parts of the body, which disappears on awaking.
An unimportant proving.
(4.) Frederick Hahnemann.
Headache on awaking ; toothache ; nausea, with several turns of
vomiting of sourish fluids and food (after 3 h.) ; after vomiting, a chill,
with heaviness in the limbs; copious flow of urine; tearing in the
occiput ; sticking tearing in the little finger.f
Who, from these insignificant vital symptomata, could recognize the
effects of the vita? arbor ?
(5.) Haynel.
Drawing-tearing headache ; corroding gnawing {obscure expression
— Mayrhofer) in the skin of the occiput for half an hour (after 13 h.) ;
feeling of dryness in the eyes ; sneezing ; tension over the right ala
nasi ; frequent epistaxis ; swelling and hardness of the left ala nasi ;
itching of the upper lip ; cutting pain in the vesical region before and
during urination, and when not urinating (after 12 h.) ; burning stitches
at the orifice of the urethra, when not urinating (after 9 h.) ; cutting
pain in the urethra when walking (after 10 h.) ; drawing-tearing in the
right upper jaw in the evening ; sticking in the right deltoid when
walking in the open air ; interrupted, burning stitches in the popliteal
space ; a lasting stitch in the left knee and external malleolus of
the right foot when at rest (after 28 h.) ; continuous burning in the
left popliteal space, as if an eruption were breaking out (after 25 h.) ;
lasting stitches in the right patella, with twitching of the skin (after
7 J h.) ; fine, rapidly succeeding stitches in the hollow of the right sole ;
coldness in the back.
Thuja speaks out clearly from this proving.
(6.) Hartmann.
Giddiness as if from turning around in a circle (after f h.) ; heaviness
in the head (after ljh.) ; momentary pressing in the head, now here,
now there (after 2 h.) ; jerking stitch through the whole head (after
* A symptom of the prover's haemorrhoids ? — Mayrhofer.
t This prover communicates the following remarkable symptom of a female
prover : " Walking is wonderfully easy to her ; it seems as though her body were
borne along by wings ; she ran several miles in an uncommonly short time arid
with unusual good feeling.''
Was this a dream or a reality? a mystification, a tarantula-dance, or an effect
of Thuja 1— Mayrhofer.
I
Provings of Hahnemann's Assistants. 15
1 h.) ; jerking pressing on both frontal eminences (after 4 h.) ; con-
strictive pressing on the left frontal eminence, which seems to depress
the upper eyelid (after l|h.) ; pressing in both temples; itching tear-
ing in the occiput (after 1 h.) ; a violent stitch in the left inner canthus
(after 1^ h.) ; pressing over the right eye ; humming in the left ear
(after 3 h.) ; pinching pain in the right ear ; a gradually increasing
stitch under the tongue, as if a needle had been stuck in there (after
4 h.) ; jumping stitches in the right side of the fauces, running rapidly
into the ear (after 6 J h.) ; violent tearing in the left upper jaw (after
2 h.) ; stiffness of the nape and of the left side of the neck (after 2 \ h.) ;
pinching in the stomach ; painful throbbing in the scrobiculus ; fre-
quent copious urination (after 4| h.) ; violent stitches in the glans,
with desire to urinate ; the urine is discharged by drops ; the stick-
ing during urination is sometimes violent and sometimes absent, and
the tenesmus continues as long as the sticking (after 7 J h.) ; pressing in
the middle of the chest, not interfering with the respiration, when sit-
ting (after J h.) ; jerking stitch in the sacrum, disappearing when rub-
bed (after 3^ h.) ; occasionally a tearing stitch in the right, and sticking
tearing in the left forearm ;* feeling of heat in all the lingers of the left
hand, while the right is as cold as ice (after 2£ h.) ; restless sleep, with
dreams ; heat in the face, with icy cold hands, and body moderately
warm (after 2 h.) ; chill over the ivhole body, without perceptible cold-
ness to the touch.
The subjective side of the Thuja-sickness is here clearly discerned ;
it also produced fever, but no permanent products of its power.
(7.) Hempel.
Drawing between the mouth and the nose ; sore pain in the right
posterior molars ; tension in the abdomen ; constipation for several
days ; pollution with the feeling in the urethra, as though it were too
narrow ; discharge of prostatic juice (without semen ? M.) ; twitching
pain of the penis on walking ; crushing pain in the upper and lower
extremities ; deceptive feeling, as if he could not stand another attack,
and was in danger of falling to pieces.
These few symptoms seem to be the meagre results of a short and
timid proving.
(8.) Langhammer.
Embarrassed head when sitting and walking ; pressive headache in
the forehead (after \ h.) ; dull pain in the Avhole body (after 1 h.) ;
lancinations along the forehead (after 5 \ h.) ; tearing pain in the left
superciliary arch, disappearing on touching it (after 11 h.) ;
swelling of the upper lid ; reddening of the left sclerotica (after 74 h.) ;
great dilatation of the pupils ; distension of the veins of the temples
* Vague symptoms lead the prover into obscure expressions, while those which
are sharply defined leave him no choice in the description. " Dolorcsipsi loquun-
t«r." — Mayrhofer.
16 Thuja Occidentalis.
and hands (after 18 h.) ; itching and boring in the left zygoma dimin-
ished by touching it (after J h.) ; boring pain in the left under-jaw
(after 1| h.) ; fine stitches in the left under-jaw ; feeling of dryness in
the lips and palate, without thirst (after 11 h.) ; itching eruption of
pimples between the eyebrows, with pus at the points ; pimples over
the whole face (after 17 h.) ; itching pimples on the knee (after 5 h.) ;
eructations of food ; bitter taste of the saliva ; violent thirst, without
heat ; nausea and vomiturition, with sweat over the whole body, with-
out thirst ; pinching and gnawing in the belly ; discharge of flatulence ;
several loose stools ; frequent urgency to urinate and discharge of
urine ; nocturnal pollutions ; crushing pains in the testicles when
sitting, aggravated by walking (after 2 h.) ; dry coryza, which becomes
fluent in the open air, and which comes on sometimes in the morning,
sometimes in the evening ; cough in the morning on rising ; sticking
in the loins when sitting and walking (after 10 h.); pains in the back
in the evening in bed ; paralytic pain in the middle of the muscles of
the left forearm, recurring both in rest and motion (after \\ h.) ;
transient sticking and drawing pams in various parts of the limbs,
disappearing on handling the parts ; voluptuous itching on the dor-
sum of the right foot and under the toes ; great weariness in all the
limbs ; drowsiness, without being able to go to sleep ; restless sleep,
with perspiration ; continued heat in the face and on the body, with
cold fingers, without thirst ; deadness of the ends of the fingers,
which are icy-cold while the body is hot, and no thirst (after \ h.) ;
frequent general shuddering (after 2\ h.) ; congestion of blood to
the head with sweat on the face, and thirst after partaking of cold
drink (after llf h.) ; dissipation of mind, unsteadiness and inclination
first to this and then to that matter ; serene temper and desire to talk
(after 12, 15, 16, h.).
Langhammer unquestionably produced the best proving of all of
the pupils of Hahnemann. It gives evidence that it is the result of
an energetic and persevering experiment in a constitution susceptible
to the effects of Thuja, by means of which both the objective and sub-
jective symptoms were brought to light.
(9.) Teuthorst.
Headache ; sticking in the temples and over the left eye ; contrac-
tion of the pupils for five days ; (? Mayrhofer) ; trembling of sur-
rounding objects while writing ; white fur on the tongue after eating ;
bitter taste of bread.
No marks of life in this abortive production.
(10.) Wagner.
Occipital headache for six hours, heaviness of the head with peevish-
ness and indisposition to talk (after 3 h.) ; drawing in the right side of
the neck, when at rest (after 3 h.) ; pressive sticking pain in the right
meatus auditorius (after 5 h.) ; ringing and roaring in the ears (after
Provings of Hahnemann's Assistants. 17
1 h.) ; pressing in the region of the left kidney (after J h.) ; burning
heat in the lumbar region (after 1 h.) ; beating and sticking in the
right groin (after 1 h.) ; frequent burning stitches through the penis
into the testicles, disappearing on motion, returning during rest (after
24 h.) ; burning stitches in the glans ; repeated stitches in the left
testicle (after 7 h.) ; tickling and itching between the prepuce and the
glans ; pressing sticking in the left side of the chest, equally percept-
ible when inspiring and expiring ; sticking between the shoulder-blades,
in the back and small of the back, when sitting ; great lassitude of the
body with disinclination to walk (after 11 h.) ; terrific dreams at night,
heat and an emission.
Thuja appears here subjectively but not objectively.
(11.) Wislicenus.
Stupefaction of the head (after 6 h.) ; tension of the skin of the
nape on moving the head (after 16 h.) ; boring in the right inner
canthus (after 3 h.) ; squeezing in the right external meatus auditorius
(after 4 h.) ; stiffness in the masticatory muscles of the left side, which
are painful when opening the mouth (after 4 h.) ; sticking and twitch-
ing in the gum of the inferior posterior molars (after 34 h.) ; a streak
of small red pimples on both sides of the neck (after 26 h.) ; red pus-
tules on the hip which bleed when scratched off (after 36 h.) ; press-
ing in the hypogastrium as if from flatulence ; ineffectual urging to
stool ; stool difficult to evacuate ; loose evacuation ; single lancinations
in the perin&um, disappearing on drawing in the anus (after 8 h.) ;
tension in the left ribs (after 1 h.) ; boring pressure over the scrobicu-
lus cordis (after 40 h.) ; drawing in the small of the back, in coccyx
and thighs when sitting (after 4 h.) ; sudden cramp pain in the small
of the back on attempting to change feet after standing a long while
(after 6 h.) ; paralytic feeling in the arms (after 8 h.) ; sticking in the
middle finger, aggravated by bending it (after 16 h.) ; pain in the left
thigh when walking as though it would break down (after 10 h.) ;
cramp pain above the left knee when sitting : intermittent pinching in
the calves (after 4 h.) ; fine stitches on the right external malleolus and
crawling twitching in the soles of the feet ; stiffness and heaviness in
all the limbs ; occasional shuddering over the back ; cold shivering with
frequent yawning (after 3 h.) ; disquieting dreams ; thirst without
heat, in the morning ; weak pulse, below 60 (after 4 h.) ; peevishness
and morose humor.
There are but few clear developments of the action of the drug in
this proving.
18 Thvja Occidentalis.
CHAPTER IV.
Results of our own Provings of Tlmja on the healthy
organism.
Thuja was proved by twenty-six persons, among whom eighteen
were males, five females, and three children. All the provings were
instituted with the tinctures and the attenuations of Thuja, except one
with the oil and the triturated twigs.
A.
Dr. Bohm instituted two provings.
(12.) First proving, with the first trituration of the dried
twigs (1 : 99).
1844, Nov. 12th. Bohm took five grains of the first trituration an
hour before breakfast (bread and milk) ; in the forenoon he experienced
slight vertigo and dull pain at the root of the nose, with a feeling of
warmth as if a cold would set in ; in the evening he experienced
several times fleeting stitches in the heel and in the ball of the right
foot, a sensation which he had never before experienced.
13th. No medicine.
14th. In the morning, B. took ten grains of the first trituration. In
the forenoon he experienced an increased feeling of warmth over the
forehead and a pressing in the right temple from without inward ;
bleeding at the nose in the evening.
15th. In the morning, took ten grains. Experienced drowsiness
in the afternoon and evening ; restless sleep at night, and frequent
urination.
16th and 1*7 th. Took no medicine.
18th. In the morning, took again ten grains of the first trituration.
Aching in the forehead, with obstruction of the nose, from which a quan-
tity of blood was blown in the evening ; painful stitches in the glans.*
1 9th. No medicine.
20th. Took ten grains in the morning. Great flow of saliva into
the mouth, frequent sneezing, bleeding at the nose, and remarkable
drowsiness after dinner.
24th. Took again ten grains of the first trituration in the mornino-.
Unusual dryness in both nasal cavities, frequent urination, xoith urging
at first, as though there was alivays water to come away, afterwards
without urging ; fleeting stitches in the heel and big toe of the left foot.
Took no medicine for seven days.
Dec. 1st. Twenty grains of the first trituration. Dryness of the pa-
late ; slight stoelling of the tonsils, painful, and inducing frequent deg-
lutition ; small white vesicles on the tongue, resembling miliary rash.
4th. Took another twenty grains. The above-mentioned vesicles on
the tongue, which had almost vanished, re-appeared with burning es-
Dr. BohrrCs Proving (13). 19
pecially after eating warm food. This was accompanied with painful
compression in the region of both malleoli of the left foot, and slight
burning during urination, the urine being redder than usual.
8th. Another twenty grains. They produced frequent eructations,
as of rancid grease ; desire to urinate ; great drowsiness in the evening.
12th. Another twenty grains in the morning. They occasioned ran-
cid eructations, violent bleeding at the nose almost every time he blew
it, and frequent urination, with burning in the fossa navicularis.
(13.) Second proving, with the tincture.
After an interval of more than two months and a half, Dr. B. insti-
tuted a second proving with the tincture of Thuja. He diluted ten
drops of the tincture with six ounces of distilled water, of which he
took two table-spoonfuls on the morning of the 3d of March, 1845, be-
fore breakfast. After the lapse of two hours he experienced frequent
eructations ; frequent urging to urinate in the daytime. Next day :
obstruction of the nose, which began to bleed as soon as he attempted
to expel air through it.
March 5th. In the morning, B. took four tablespoonfuls of the above-
mentioned dilution. Headache in the forehead with warmth, frequent
urination with urging, slight burning under the sternum, painful
pressure at the root of the nose. These symptoms disappeared gra-
dually within three days.
10th. Eight spoonfuls of the same dilution. Result : continued ran-
cid eructations ; oppression of the chest ; frequent hawking and hack-
ing ; continued burning along the whole length of the sternum ; fre-
quent urination followed by long-continued urging.
15th. B. took, as a final experiment, ten drops of the undiluted tinc-
ture on sugar. The effects were rancid eructations (for eight hours) ;
fluent coryza, disturbing the night's rest ; weight on the chest ; painful
stitches in the big toe of the left foot ; frequent urination with urging.
All these symptoms increased on the day following, subsequent^ de-
creased, and disappeared entirely in a few days.
It is to be regretted that B., whose organism seemed to possess a
great susceptibility to the effects of Thuja, did not pursue his experi-
ments with more perseverance.
B.
Doctor Frohlich proved the Thuja on himself, and on one girl and
two rabbits.
I.
frohlich's provings of the thuja on himself.
F. instituted six separate provings with Thuja.
20 Thuja Oceidentalis.
(14.) First proving, with the juice of the chewed branches of
Thuja.
1844, Dec. 20th. F. began his proving by chewing a few fresh twigs,
and swallowing the juice. He experienced no change in his feelings.
21st. In the morning he repeated the experiment, and experienced,
in the afternoon, protrusion of the hemorrhoidal vessels, with sticking
in those vessels when walking; in the evening, ten hours after swallow-
ing the juice, he felt a tearing in the left knee-joint, extending to the
middle of the calf, commencing while sitting and lasting only a short
while.
22d. In the morning the experiment was made a third time. Soon
after he felt a continuous, digging and burning pain in two upper hol-
low molars of the right side ; in the evening, ten hours after swallowing
the juice, he experienced short but frequently returning paroxysms of
a lancinating pain from the left acetabulum down to the calf, deep in
the bone (while walking, in the street). The toothache was removed
by a dose of Merc-sol, 3.
No chewing on the 23d, lest the toothache should occur again.
The toothache returned, nevertheless, whenever he entered a warm room
from the street and remained there a little while. He tried the nitrate
of silver 6. with but temporary relief ; and the troublesome toothache,
for which cold water was the only palliative when the pain was very
violent, disajmeared gradually in some days.
(15.) Second proving, with the third dilution.
The symptoms of the former proving having entirely ceased for
several days, on the 2d of Jan., F. took three drops of Thuja 3. in a
tablespoonful of water, before breakfast. No result.
Jan. 5th. In the morning, six drops of the same preparation. A
'painful stitch through the centre of the left eye, commencing in the
centre of the brain ; a few stitches in the external tuberosity of the left
thigh when walking ; the above-mentioned toothache again made its
appearance, but only under similar circumstances.
12th. Twelve drops in a glass of water. After walking in the open
air for half an hour, he entered a warm room, where the above-de-
scribed toothache again made its appearance, but soon abated and
disappeared on using cold water. This symptom returned as often as
F. entered a closed apartment, even though not heated, and remained in
it for a while. The toothache was immediately diminished by inhaling
the air at an open window for a few moments. On the same day the
following symptoms were observed : drawing tension in the nape of the
neck (more on the left side), recurring several times ; feeling of weakness
in the chest ; frequent emission of flatulence which had not much smell ■
drawing, and fleeting deep stitches in various parts of the body.*
* These fleeting stitches resemble slight electric shocks — Mayrkofer
Dr. Fro Mich? 8 Proving (16). 21
No medicine was taken from the 8th to the 19th ; the toothache
recurred during all this time under the circumstances indicated above,
although several remedies, such as mere-sol., campk., sabina and nux
were taken to remove it.
(16.) Third proving, with the tincture.
Jan. 2 2d. After the toothache had entirely subsided, F. took twenty-
drops of the tincture in a glass of water. That same forenoon the
toothache returned ten minutes after having entered a room without
fire ; after dinner he experienced a piercing stitch in the left hypochon-
dria, and a continuing squeezing-sticking pain in the concha of the left
ear.
23d. In the morning, thirty drops. At noon he was unable to dis-
tinguish by the taste what sort of soup he was eating (it was dark).
Nor was he able to discern the vegetables by the taste, and black coffee
tasted like warm water, without aroma.
24th. Forty drops : stitches in the region of the liver when sitting.
25th. The same dose produced a slight colicky pain in the small
intestines and a few stitches in the right thumb.
26th. Another forty drops : painful stitches in the inner side of the
left knee-joint when standing.
27th. Sixty drops. In the forenoon he experienced a few deep
stitches in the left hypochondria.
28th. Eighty drops. In the forenoon : pinching pain in the stomach,
and a feeling of fulness and of being bruised in the chest under the
sternum ; which last symptom he had observed for several days past.
No Thuja was taken from the 29th of January to the 3d of Febru-
ary. During this period the following symptoms were observed :
single deep stitches in the right and left hypochondria ; gnawing-
stinging pain in the stomach (coming on in bed and going off after
rising) ; drawing-sticking pain in the head of the left femur ; dulness
of the senses of taste and smell.
Feb. 3d. F. took one hundred drops of the tincture in a tumblerful
of water before breakfast. An hour after, he experienced a single stitch
through the lower portion of the lungs from behind forward. This
was accompanied by a bruised sensation in the chest with dulness of
the head, sad mood and discouragement, being the same in the open
air and in the room. Afterwards the well-known toothache made its
appearance again in the usual paroxysms, and in the evening, while
sitting in a crowded theatre, he experienced a drawing-sticking pain
in the right forearm, extending from the elbow to the wrist-joint.
4th. He experienced a painful stitch through the occiput from above
downward.
5th. The troublesome toothache came on again as often as F. en-
tered a closed apartment from the open air, and continued until the
23d of February. During that period F. had several characteristic
symptoms of Thuja, especially in the limbs, but which were not noted
22 Thuja Occidentalis.
down because he had taken several remedies, such as sabina, rhus, and
mezereum, against the toothache with only transitory relief.
(17.) Fourth proving, with the eleventh dilution.
April 4th. Before breakfast, F. took twenty drops of the 11th dilu-
tion, in three ounces of distilled water. While proving the attenua-
tions, he avoided every kind of spirituous beverage, and partook of the
plainest food.
6 th. He felt vertigo with fulness in the head, and the hands became
easily stiff and tired when moving them.
7th. Twelve drops of the 1 1th potency produced the following re-
sult : in the forenoon, while walking in the street, he felt a few deep
stitches in the right groin ; afterwards he felt a violent drawing tearing
from the left elbow-joint as far as the two middle fingers ; vertigo
at home, with vanishing of the letters when reading, and a continued
digging pain in two hollow upper molares of the right side, relieved by
cold water, but increased by warm soup and tobacco-smoke.
8th. F. feeling debilitated all over as by fatigue, and gloomy, was
compelled to take a little wine, after which all the above symptoms
disappeared.
(18.) Fifth proving, with the tincture again.
April 2 2d. After all the symptoms of Thuja had ceased and the
carious teeth had become entirely free from pain, F. took eighty
drops of the tincture before breakfast, after which he swallowed a
glass of water. No effects were observed either this or the next day.
On the 24th and on the 26th he took one hundred drops each day.
On the latter day the prover experienced considerable dulness of the
head and mistiness of sight ; on the dorsum of the right foot a small
blotch was discovered with a red areola, which rendered walkino- in
boots difficult.
28th. Another hundred drops. The blotch is diminishing, and noth-
ing remains of it except a dark-red, somewhat elevated spot with a
lighter areola, still impeding walking. General weariness during the
day, as if he had slept none all night. These symptoms are accom-
panied by dulness of the head, sad mood, dulness of taste, indistinct
sight, and bad, sunken appearance.
Nevertheless, on the 30th, F. took another hundred drops. In the
forenoon : dulness of the head, with vanishing of objects when attempt-
ing to fix them. In the afternoon : painful stiffness of the nape of the
neck when moving the head, bruised sensation in the chest, dulness of
taste and very gloomy mood. The efflorescence on the dorsum of the
foot began to subside.
May 2d. Another hundred drops elicited no new symptoms.
No medicine was taken on the 3d and 4th of May ; durino- this
period F. observed the following symptoms : dulness and feelino- of
Br. FrohlidCs Proving (19). 23
fulness in the head, with ill-humor and drowsiness. After a siesta of
three quarters of an hour : vertigo so that he could scarcely Avalk
^without holding on to something ; great sensitiveness of the skin to
cool air.
5th. F. took the last hundred drops. Result : sticking tearing in
the right tarsal joint in the forenoon, while walking. Another little
blotch makes its appearance in the still existing red spot on the dor-
sum of the right foot, impeding the walking very much.
6th. In the morning, in bed : sticking beating in the right hand
extending as far as the tips of the fingers and in the anterior part
of the right foot. Towards noon : pressive headache with pressure
in both eyes, accompanied with gastric uneasiness and reddened urine.
F. had to lie down on account of his increasing debility, and was not
able to go to sleep for several hours.
7th. He felt a general debility as from fatigue ; feeling of fulness
in the head ; a paralytic burning sensation, which had been felt
already for some days past in all the muscles of the forearm, and
which extended as far as the tips of the fingers, was particularly trou-
blesome (coming on when moving the arm, going off in rest). In the
afternoon and evening : feeling of coldness through the back, with
debility and stiffness in all the limbs ; dulness of the head ; sticking
pain in the left patella when going up stairs ; great debility in the
small of the back and feet, and a feeling of weakness in the chest.
8th. After having spent a night full of dreams, F. woke greatly
improved ; the head continued dull, and he was attacked with turns
of vertigo after talking long; at noon he felt chilly all over, espe-
cially on the extremities ; he was ill-humored and restless, and had
canine hunger without thirst. A small quantity of wine which he
took at dinner without relishing it, aggravated the headache very
much, and smoking increased it to vertigo.* At eight o'clock in the
evening: aching pain, especially in the frontal eminences and tem-
ples ; vertigo when walking ; bruised pain in the shoulder-joints and
upper arms ; weak feeling in the chest with pressure under the sternum
and difficulty of breathing, especially while going up stairs.
9th. F. felt better in every respect, all the symptoms disappeared
within a few days, except the weak feeling in the chest and the diffi-
culty of breathing in going up stairs, which did not entirely leave
him until the end of the month.
(19.) Sixth proving, with the recent juice.
May 21st. F. swallowed before breakfast a table-spoonful of recently
expressed juice, obtained by crushing the twigs of Thuja and pouring
upon them a mixture of equal quantities of distilled water and alcohol.
Of this nauseous juice F. took another table-spoonful on the first and
second of June, and two table-spoonfuls on the third. 9
* As the use of wine was beneficial previously, this aggravation seems to be
rather attributable to the effects of a meal eaten with canine appetite. — Mayrhofer.
24 Thuja Ocddentalis.
On the last day lie experienced in the forenoon frequent paroxysms
of tearing and sticking in both hands, which became so violent in the
middle of the right ulna while he was writing, that he had to give it
up. In the afternoon, while driving in a carriage, he experienced a
very violent tearing in the left forearm, which was especially violent in
the anterior tuberosity of the humerus, that region becoming very
sensitive to the touch. Moreover, prickings in the fingers of the
same hands. These symptoms continued while driving, and did not
abate until F. got into a profuse perspiration in the evening, while in
a crowded theatre. Upon moving the hand quickly and strongly he
felt a burning pain in all the muscles of the forearm.
June 4th. F. again took two table-spoonfuls of the recent juice,
which did not produce any new symptoms. The tearing pain in the
anterior tuberosity of the left humerus continued, was increased by
motion, and was heightened to a burning pain by contact, especially
after the painful spot on the arm had been knocked against something
though only slightly. The red spot on the dorsum of the foot impeded
his walking very much. Under the sternum he experienced an oppres-
sion with a bruised sensation in the chest. These symptoms were
accompanied by frequent hawking of mucus, dulness of taste, with great
appetite and swelling of the hemorrhoidal veins.
5th. The following symptoms were observed: sensitiveness of the
anterior tuberosity of the left upper arm, especially when touched ;
in the afternoon, feeling of fulness in the head with drawing pain in
the nape of the neck ; feeling of weakness in the chest ; painful stiffness
in the left forearm extending as far as the fingers, and impeding mo-
tion : pressing sensation in the turgid hemorrhoidal veins ; sticking-
burning pain in the external tuberosity of the left tibia (coming on
when sitting and increased by pressure). All these symptoms disap-
peared gradually on the following days except the great sensitiveness
in the tuberosity of the humerus, which seemed to become more and
more circumscribed every day, but which only entirely disappeared in
the course of a week. The last to yield was the hcemorrhoidal con-
gestion, to remedy which he used several bottles of mineral water.
II.
frohlich's proving of thuja on an unmarried woman.
(20.) First proving, with the third dilution.
Caroline Philipp, forty-five years old, the same person who assisted
in proving Colocynth, took ten pellets, moistened with the 3d dilution
of Thuja, on the 14th of November, 1844, before breakfast. Two
fours after, she experienced a drawing from the left axilla as far as the
elbow-joint; afterwards a drawing along the vertebral column and in
the calves, with a feeling of weakness in the feet.
Dr. Fr'ohlichbS Proving (21). 25
Nov. 13th. The prover again took ten pellets, which elicited the
following symptoms : drawing from the right wrist-joint as far as the
tips of the fingers, and from the right calf as far as the malleoli, with
the sensation as if that foot were lame ; afterwards a drawing from the
right elbow as far as the wrist-joint ; then a transient paralytic feeling
in both thighs as far as the knees.
14th. After another ten pellets, she experienced a weakness in the
knees and a decrease of appetite.
No medicine was taken on the 15th, 16th, and 17th; during the
first two days the above symptoms were yet slightly felt.
From the 18th to the 23d, Caroline took ten pellets every day, and
observed the following symptoms : drawing sticking in the right up-
per arm as far as the elbow-joint, and in the right thigh as far as the
knee ; sticking in the right forearm as far as the finger-joints ; drawing
in both scapulae in the direction of the nape of the neck, in both legs
from the knees to the malleoli, and at the same time in both forearms
from the elbows to the wrist-joints. These symptoms generally ap-
peared three or four hours after taking the drug, and lasted from ten
to sixteen hours.
The prover discontinued the medicine until the 26th of November,
when she took another ten pellets. On that day she experienced a
sticking in the left thigh as far as the knee, single stitches in the left
tarsal joint, and in the evening drawing in both thighs.
27th and 28th. She again took ten pellets each time, after which
she experienced a tearing in the left upper arm, afterwards in the left
leg ; sticking in the left wrist-joint extending as far as the tip of the
index finger ; drawing in the left calf, afterwards in the right forearm
from the elbow as far as the wrist-joint.
Dec. 5th, 6th, and 10th. She took ten pellets each time without ex-
periencing any new symptoms. The same drawing and sticking was
experienced in various parts of the limbs. On the inner surface of the
left forearm a red, round, itching spot (of what size? — M.) was ob-
served with white vesicles raised upon it, which burst, poured out a
clear lymph, and left a yellowish crust behind.
(21.) Second proving, with the two hundred and second
dilution.
Dec. 12th. Before breakfast, F. gave the prover ten pellets of Thuja
202, without her knowing that the preparation was different from what
she had previously taken. Results : drawing in both hands and feet,
afterwards only in the forearms as far as the wrist-joints, and sticking
in both sides of the chest.
13th. She took another ten pellets, with the same result.
19th and 20th. She took the usual number of pellets, and observed,
besides the symptoms mentioned above : drawing in both hips from
without inward and from above downward toward the genital parts.
After an interval of twelve days, the prover took ten pellets of Thuja
26 Thuja Occidentalis.
202 on each of the following days : 2d, 3d, 4th, 6th, 7th, and 9th of
January, 1845. After every dose she experienced tearing, drawing
or sticking sensations, accompanied with repeated attacks of vertigo,
and a feeling of stiffness in the feet and back, as far as the nape of
the neck.
The prover having taken cold, in consequence of which she was at-
tacked with toothache and a swelling of the cheek, the experiments
were concluded. F. mentions that the prover had frequently asserted
with great positiveness, that she had experienced with more intensity
all her former symptoms ever since the 12th of December, when she
took the first dose of Thuja 202. We ought to state that the prover
observed a very plain diet during the whole period of the proving.
From the results of the last two provings, Dr. Frohlich draws the
following inferences :
1. Thuja specifically affects the sero-fibrous tissues.
2. It develops its effects chiefly in the extremities, and mostly in
the direction of the limb from joint to joint.
3. The symptoms of Thuja produced by the different dilutions have
much more similarity to one another than is the case with other drugs.
4. By this experiment with the 202d dilution, the power of the
high attenuations (hoch-potenzen) to produce effects on the healthy
human organism is perfectly established. Dr. F. does not consider
this astonishing, inasmuch as the delicately-organized prover lived very
plainly, and inasmuch as he had seen decided effects from many of the
other highest potencies in his ordinary practice.*
C.
Doctor William Huber, of Linz, instituted three provings upon him-
self with the Thuja.
(22.) First proving, with the lower dilutions {prepared
according to the decimal scale).
One drachm of the third attenuation which H. took on the 14th of
September, 1 844, at 8 o'clock in the morning, produced no effect, He
took a similar dose on the 13th at 5 o'clock in the morning ; after an
hour and a half, while lying in bed, he experienced a momentary
starting in the epigastric region, in the direction of the left hypocon-
* We may here be allowed to remark that the alleged effects of high potencies
on the healthy and on the sick, must be considered as exceptional cases until more
copious statistics shall be at our command. We must remember that one swallow
does not make a summer; of a hundred magnetic subjects scarce one or two be-
come clairvoyant, and it may be that the same relative proportion holds as to the
sensibility of sound and sick to high potencies — " High potencies for highly -po-
tentized nerves — Similia similibus /" — Mayrhofer.
Br. W. Hubert Proving (22). 27
drium, as of something alive. Next day he took a third dose of the
same dilution, but observed no further symptoms.
Sept. 15th. At 6 o'clock in the morning, H. took one drachm of
the fifth dilution. One hour after dinner he experienced a fine, tran-
sitory stitch in the posterior surface of the left ulna near the elbow ;
soon after a sudden starting-bounding sensation in the right iliac re-
gion, as though from something alive ; a quarter of an hour afterwards,
he experienced a painful drawing in the outer surface of the left up-
per arm near the olecranon, recurring several times at short intervals.
At 8 o'clock in the evening, H. experienced a sensation on the glans
near the frenulum prseputii, as if the spot had been excoriated, al-
though no change was visible.
16th. Took a similar dose, after which: the same feeling of soreness
on the glans, only when touching it ; at 4 o'clock, after dinner, he ex-
perienced a few fine stitches in the fossa navicularis of the urethra ;
an hour afterwards, during the siesta, he experienced a second time a
sudden bounding up in the abdomen, accompanied with starting of the
whole upper part of the body, as if from fright.
l*7th. After a similar dose a drawing intermittent pain in the left
side of the forehead, and at the same time symptoms of colic, accom-
panied by emission of flatulence.
18th. A drachm of the fourth dilution morning and evening; this
caused a profuse secretion of insipid saliva in the night, and a painful
tension in the right side of the nape and in the small of the back.
19th. The dose was repeated, causing a slight tension in the left side
of the nape, and a pretty severe sticking crosswise where the radius and
the carpus unite, from without inwards (in rest).
20th. In the morning, H. repeated the dose. After the lapse of an
hour he felt as if his stomach were deranged, with pressure over the
scrobiculus, which impeded respiration. At 9 o'clock he experienced
a pain in the left side of the forehead when writing, which continued
the whole forenoon ; upon being waked from the siesta H. became
quite giddy, and had great trouble in collecting his thoughts.*
21st, 22d, and 23d. H. took one drachm of the third dilution at 7
o'clock in the morning. On the first day, towards 9 o'clock in the
morning, he experienced an aching in the epigastrium, towards the
right hypochondrium, for half an hour (more in rest than when walk-
ing). On the morning of the second day, dulness of the head, and at
10 o'clock, painful drawing in the left thumb, lasting only a short while,
but returning frequently. On the third clay a sudden sensation of gid-
diness was experienced at 11 o'clock in the forenoon while writing. He
felt as if a current of air was ascending from the occiput and pene-
trating towards the forepart of the head, causing vertigo and a loss of
thought.
24th, 25th, and 26th. H. took one drachm of the second dilution in
the morning. Result : after the first dose he experienced a momentary
* Was this the effect of sleep or of Thuja? — Mayrhofer.
28 Thuja Occidentalis.
tearing in the dorsum of the left hand, at noon, while writing ; after
the second dose several stitches were experienced periodically in the
left side of the chest, apparently deep in the pectoralis major muscle.
The third dose was without result. One drachm of the first dilution,
taken on the 27th, 28th, and 29th of the same month, was likewise
without result.
(23.) Second proving, with the tincture.
Five drops on the morning of the 30th September, produced no
effect.
Oct. 1st. Eight drops. In the evening, while chewing a piece of
bread, H. experienced an intense sticking pain between the left ear
and zygomatic arch, as if the jawbone had suddenly become dis-
located, extorting a scream. This pain was experienced every time
he attempted to chew, continued the whole evening, and was still felt
the next morning.
2d. In the morning, ten drops. As soon as he awoke he felt an
extremely disagreeable, painful sensation in the nape of the neck, close
to the occiput, as if he had been lying on a hard couch. In the course
of the day this pain spread over the whole of the right side of the back
as if the muscles in that part of the body were sprained, and was felt
especially when bending the head forward and raising the right arm.*
In the evening the pain moved more into the region of the right
shoulder and neck ; upon chewing bread the before-mentioned pain in
the muscles of mastication was again experienced.
3d. In the morning, sixteen drops. After dinner a voluptuous itch-
ing in the forepart of the urethra, while the penis was relaxed. The
pain in the right posterior cervical and dorsal muscles continued the
whole day, accompanied with whizzing and buzzing in the right ear.
On bending the head forward he experienced a sensation as if the mus-
cles were too short, and as if the pain was caused by the tension of the
muscles. Had a quiet night after taking forty drops in the evening.
4th. Twenty-six drops. Shortly after taking the drug the pain in
the nape of the neck, shoulder and back, was increased to such an
extent that the raising of the right arm and carrying the hand behind
the head caused the most exquisite pain. He was unable to bend
the head forward or to turn it ; in order to accomplish this he had
to move the whole upper part of the body. The pain was a sort of
tumultuous digging, as if the muscles had been crushed, and as if
a gathering were taking place in the subcutaneous and intermuscular
areolar tissue. On the same day he had two papescent fetid stools
and, in the evening, after eating a warm soup, a vaporous perspiration
broke out all over the body, continuing for half an hour, and followed
by a diminution of the pain in the nape of the neck ; on the following
* Dr. Huber observes that he had never been affected with rheumatism of the
nape of the neck. — Mayrliofer.
Dr. W. Ruber's Proving (23). 29
day, however, H. was not yet able to tie his cravat behind, or to hang
the cbain of his watch around his neck. On looking at the right
shoulder in the glass, it was found to be somewhat more elevated
than the left, and swollen ; the taste in the mouth was insipid, with a
sensation as if the stomach were disordered.
5th. Thirty drops. At 8 o'clock in the morning he had a large
evacuation, which was at first hard, afterwards papescent, clayish and
fetid. The disagreeable sensation in the stomach continued all day.
At half past 1 in the evening, painful tension in the bottom of the left
orbit for several minutes.
8th. Sixty drops. After the lapse of half an hour : several painful
stitches in the forepart of the urethra, the penis being relaxed ; after-
wards he felt a transitory cramp pain in the right ear, and several times
fine prickings in various parts of the skin as if with needles, which
sometimes changed to a burning ; also a painful burning sensation
between the prepuce and glans, continuing from 6 to 7 seconds, and
returning several times at short intervals, without any change in the
parts perceptible to the eye. At 10 o'clock in the forenoon he expe-
rienced a painful drawing in the left frontal eminence (while walking
in the open air) and an itching of the anus, which induced scratching.
At 4f in the afternoon, while sitting, q sensation in the urethra, as
if a drop of viscid fluid were pressing forward. At 5 o'clock drain-
ing pains were experienced directly below the right internal malleolus
(for a few seconds). On the morning of the following day, the orifice
of the urethra was closed with a slimy fluid, consisting of a serous liquid
and a lump of mucus, which could be drawn into threads by the fin-
gers. After removing this liquid a slight burning was experienced on
urinating.
9th. In the morning, H. took eighty drops. After the lapse of
fifteen minutes the left eye began to water, the right one remaining
dry ; confusion of the head the whole forenoon ; whizzing in the left
ear ; painful pressure in the superior and posterior angle of the left
parietal bone, as if a small convex button were pressed against that
part (going off rapidly when touching it). At 10 o'clock in the
forenoon painful drawing, extending from the bend of the right thigh
to the internal surface of the thigh for a few seconds (in rest).
After dinner a pain in the right parietal bone, as if a pointed nail
had been driven in ; violent vertigo when sitting and closing his eyes,
as if the sofa upon which he was sitting were balancing to and fro
(going off immediately when opening his eyes).
At 4^ o'clock, during the siesta, he experienced a momentary, dart-
ing pain in the gums of the right upper jaw. (The affection of the
back and nape of the neck had again by degrees wholly disappeared.)
10th. One hundred drops : after the lapse of two hours transitory
jerking formication in the fossa navicularis of the urethra, accom-
panied with a voluptuous feeling without erection ; dulness of the head
the whole forenoon, with paroxysms of a drawing pain in *he middle
30 Thuja Occidentalis.
of the forehead, which was especially violent in the left frontal eminence,
and thence extended to the posterior portion of the left eyeball, and at
times as far as the occiput, and at 3 o'clock in the afternoon passed into
a constant digging pain. This headache was as violent in the open air
as in the room, and lasted until 10 o'clock at night. Occasional sen-
sation in the right epigastric region as of something alive moving there ;
frequently a painful jerking in the penis, accompanied by a sensation
as if a viscid liquid were exuding from the urethra, which, however,
was not the case. He fell asleep after midnight ; on the following
day, when waking at half past 6 o'clock, a dull drawing pain was
experienced in the right frontal eminence, extending as far as the
right orbit and the right nasal bone, setting in in paroxysms and ending
at 8 o'clock.
The right eye was dry and in the margin of the lower lid there was
a burning spot as if a stye were about to form. He felt, besides, whiz-
zing in the left ear, and once a fleeting stitch in the left testicle.
11th. At 8 o'clock in the morning, H. took one hundred and
twenty drops. After the lapse of an hour, a jerking, voluptuous
formication was experienced in the forepart of the urethra (while
walking in the street), his penis being relaxed. At 10 o'clock in the
forenoon : painful drawing in the right side of the forehead, ceasing
and returning several times. At half past 12 : painful drawing in
the left posterior cervical region, close to the occiput, alternating
with a similar pain in the right frontal eminence. Afterwards creaking
in both ears when swallowing, resembling the turning of a wooden
screw, accompanied with sticking and a feeling of dryness in the right
outer canthus, as if a grain of sand had got into it. At 2 o'clock in
the afternoon he experienced frequent attacks of a painless twitching in
the back towards the left loin like a muscular twitch.
On waking the next morning, the scrotum, perinseum, and the inner
surfaces of the thighs were dripping with sweat,* and, a few minutes
after, paroxysms of a drawing pain were experienced in the bottom of
the right orbit, continuing a quarter of an hour.
The same phenomena continually recurring, H. concluded the prov-
ings with the tincture by taking 140 drops of it at 8 o'clock in the
morning on the 12th. After the lapse of a quarter of an hour, a feeling
of dryness in both eyes, with painful sticking and creaking in both ears
as when a wooden screw is turned, especially during empty deglutition.
Half an hour after, a short painful drawing in the left side of the occiput.
Two hours after, a clawing aching pain in the left frontal eminence,
becoming fixed in a small place (for a few minutes) accompanied with
rumbling in the bowels. After nine and a half hours colicky pain in
the right iliac region, for a few minutes, while walking in the room •
shortly after, a few shooting stitches in the urethra, and a drawing
* Dr. H. observes that this sweat of the genital organs reminded him involun-
tarily of the assertion of his teacher, Von Hildenbrandt : " Amant condylomata
loca uda ut fungi."
Dr. IF. Ruber's Proving (24). 31
headache in the right forehead. These symptoms lasted with more or
less intensity during the subsequent days, and a few more were felt on
the 21st, such as, feeling of soreness about the hard palate, as if burnt
and covered with vesicles ; periodical pinching in the middle of the left
calf as if a convex button were pressed upon that part, the same sensa-
tion being experienced in the mastoid process of the right side ; shoot-
ing stitches from the neck of the bladder towards the urethra.
These phenomena became gradually weaker, though some of them
were yet experienced on the 30th of Nov., 1844, more than six weeks
after the prover had taken his last dose of Thuja.
(24.) Third proving, with the sixtieth dilution.
After all the symptoms produced by the increasing doses of the
tincture of Thuja had entirely disappeared, H. experimented with the
60th dilution (1 : 99), not, however, without a pre-formed conviction
that the experiment would be wholly without result and was therefore
much astonished at again experiencing not only many of the old symp-
toms, but also others, which he had never before felt.
1845, Jan. 16th. H. took ten drops of the 60th dilution at 11
o'clock in the forenoon. After a quarter of an hour a slight pressure
in the pit of the stomach and in the chest, impeding respiration.
Sticking tearing pain in the muscular parts of the right side of the
nape of the neck, in the evening, extending as far as the scapula
(continuing only a short while, but returning several times with consi-
derable violence). Soon after, a similar pain in the left forearm, where
the ulna joins the carpus. On the morning of the day following, H.
experienced a sensation in the abdomen as if a child's knee were push-
ing against the anterior abdominal walls from within.
17th and 18th. Ten drops produced no symptoms.
19th. The same dose occasioned the following symptoms: voluptu-
ous itching in the forepart of the urethra, the penis being relaxed, ac-
companied with a sensation as if a few drops would flow out ; jerking
in the left hypochondrium, towards the epigastrium ; transitory pain in
the left frontal eminence as if a nail were driven in. This pain dis-
appeared at once on touching the part, returned, however, immediately
at the superior posterior angle of the left parietal bone, as if a convex
button were pressed against the part.
20th. Twelve drops at 10 o'clock in the morning; frequent lachry-
mation of the left eye (when walking in the open air) ; digging head-
ache in the left fron tal eminence at 5 o'clock in the afternoon, return-
ing several times at short intervals, and alternating with the sensation
as if a convex button were pressed upon the part near the vertex.
This same sensation, which ceased immediately upon the parts being
touched, and returned again as soon as the contact ceased, was expe-
rienced several times in the right mastoid process, in the left parietal
bone, and under the right clavicle. In the evening he perceived a
painful little tubercle in the middle of the left eyebrow, and, after he
32 Thuja Occidentalis.
had gone to bed, a digging-tearing pain was experienced in the muscles
of the right side of the nape of the neck, extending momentarily as far
as the right scapula, and being relieved by contact, accompanied by
roaring in the left ear and creaking when swallowing saliva. On the
following morning, after waking, pressure and tension in the left and
afterwards also in the right orbit.
21st. Took fifteen drops. In the afternoon, the well-known pressure
as with a convex button in a region of the left parietal bone. At 7
o'clock in the evening, H. suddenly experienced a momentary pressure
as of a nail which had been driven in, in the left frontal eminence
(while walking in the street), and after returning home and entering
the room, a luminous disk of the size of a pea hovered before his eyes-
it shone like a fire-fly (lampyris noctiluca).
2 2d. No medicine was taken. In the evening he experienced a
transitory pain in the left frontal eminence as of a nail which had
been driven in.
23d. H. concluded his provings with seventeen drops of the 60th
dilution. At 10 o'clock in the forenoon, drawing-sticking pain in the
left temporal muscle, increased by mastication and diminished by con-
tact. This pain continued for two hours, and in the open air as well
as in the room. At the same time H. experienced a beating tearing
with sensation of heat in the right frontal eminence, and a pinching
pressure in the dorsum of the left foot, occurring frequently during
the day.
24th. On waking, drawing pain in the left frontal eminence (this
pain had made its appearance already in the evening after lying down),
and profuse sweat about the genital organs. In the forenoon, while
walking in the open air, headache in the forehead over the left eye-
brow, extending as far as the right side of the forehead. In the even-
ing, a continuous drawing and tension below the mastoid 2>rocess of
the right side, accompanied with occasional drawing in the left frontal
eminence towards the temple, and with roaring in the left ear.
25th and 26th. No symptoms observed ; but on the 27th, a few
moments after waking, H. had a complete hemicrania* in the left side
of the forehead. It was a violent, drawing pain, commencing directly
over the left upper eyelid, extending perpendicularly upward through
the middle of the left eyebrow, and dividing in the left frontal eminence
into a number of threads and rays which penetrated deep into the
brain. This symptom lasted a few minutes, and disappeared as rapidly
as it came.
Feb. 13th. On this date, clear Thuja symptoms having been con-
stantly present in the intermediate period, H. discovered a painless
nodule near the borders of the hairs on the left side of the nape of the
neck, disappearing again on the following day, except a small rouo-h
place.
16th. A tubercle was observed on the inner side of the right thio-h.
* H. had never tad any hemicrania before. — Mayrhofer.
Dr. W. Ruber's Provings (25). 33
an inch and a half from the perinamm, which felt like a wart and
looked dark-red, of the size of a hemp seed, the tip having a dingy
white appearance, and the base being surrounded with a bright-red
areola of some three or four lines wide ; it was somewhat painful when
touching or moving it, and was filled with pus on the day following.
A few days afterwards it changed to a brown scab, which came off
spontaneously.
The most remarkable thing in the provings of Huber, is the length
of time during which he observed the effects. Even as late as the
10th of March, forty-six days after he had taken any of the drug, he
distinctly, although feebly, felt several of the effects of Thuja. The
symptoms of the head lasted longest and were most frequent, especially
the sensation as if a nail had been driven in in the angles of the parie-
tal bones ; as this sensation ceased, an itching gnawing was experienced
in the same region, which induced him to scratch. The sensation as of
something alive in the abdomen, and the seeing of a luminous disk
shining like a fire-fly, lasted as long. This was sometimes perceived in
the daytime, but most frequently at twilight in the room. Afterwards
this luminous circle, which followed the movement of the eyeball, and
was hovering at various distances now before one, now before both eyes,
assumed a more elliptic form, and had a dark violet or blackish nucleus
in the centre. Sometimes the disk was of the size of a millet or hemp
seed only, but always luminous on the edge.*
D.
W. Huber, brother of the former prover, surgeon at Kleinzell, proved
the Thuja on six persons ; on himself, on two females, one of whom
was his own wife, and on three of his children.
w. huber's provings of thuja on himself.
W. H. instituted three provings on his own person.
(25.) First proving, with dilutions.
1845, April 19th. W. H. commenced with the 30th dilution, taking
every morning before breakfast 100 drops, and descending in the scale
of the dilutions, until he had reached the first on the 18th of May,
when the first proving was concluded. After taking the 21st dilution,
he for the first time experienced a slight pressive headache over the
right superciliary eminence; after the 20th dilution, violent pressive
* We may be permitted to remark, that in our opinion the 60th potency would
not have excited so many symptoms, if the provings with the massive doses had not
gone before. If the organism has been once thoroughly impregnated with large
doses, the least quantity of the drug excites a new reaction as long as the first
disturbance is not entirely counterbalanced. — Mayrhofer.
C
34 Thuja Occidentulis.
headache commencing in the region of the posterior and inferior angle
of the left parietal bone and extending as far as the rio-ht frontal emi-
nence. The pain only lasted while the prover remained in a state of
rest : every movement diminished it and it returned immediately after
the movement ceased. This pain became especially violent after the
19th dilution. It commenced half an hour after taking the medicine,
and lasted all day. Even on the day following he was awakened by it
at 5 o'clock in the morning and was compelled to rise, after which it
ceased ; the head, however, remained stupid and full. This was ac-
companied on the same day by frequent attacks of a boring pain in the
region of the bladder, with painful drawing up of the testes.
From the 1st until the 12th of May, W. H. took from the 18th to
the 7th dilution. The headache continued with more or less violence ;
on the last day it was accompanied with roughness of voice and a
scraping sensation in the throat, which, however, continued only a few
hours.
From the 13th to the 18th of May he took from the 6th to the 1st
dilution. The headache gradually disappeared. In the place of this,
H. had almost daily attacks, and sometimes several attacks a day of the
boring pain in the region of the bladder, -with painful drawing up of
the testes, which was accompanied with occasional urging to stool. All
these phenomena were but slightly marked during the last period of
the proving, and disappeared in a few days after the medicine was
discontinued.
(26.) Second proving ', with small doses of the tincture.
June 18th. W. H. took 10 drops of the tincture before breakfast, in-
creasing the dose every day by 10 drops.
During the first days the above described headache again made its
appearance, but it was less violent and ceased entirely after the fourth
day. On the 5th day, an hour after taking the drug, he experienced
a sensation in the right side of the throat as though it were about to
inflame ; during the whole of that day he experienced stinging pains
when swallowing, which disappeared again entirely in the subsequent
night. No symptoms made their appearance from the sixth to the
tenth day, except nausea on taking the drug ; this nausea was excited
even by the mere sight of the medicine.
(27.) Third proving, with large doses of the tincture.
July 7th. W. H. took 200 drops of the tincture, and repeated that
dose on the 1th, 9th and 1 2th of the same month.
Every time he took the dose, he felt nauseated and disposed to
vomit. The above described headache appeared again immediately
after taking the first dose, but it never reached the violence which it
had while proving the attenuations, although it continued until the
Dr. W. Huberts Provings (29). 35
15th of July. The giddiness and the obtuseness of the head, on the
contrary, were more violent. These symptoms were accompanied with
want of disposition to do anything, ill humor and inclination to anger,
pain in the throat during deglutition, and sour-smelling sweat almost
every night. These phenomena continued in greater or less intensity
during the proving, and even a few days beyond.
H. thinks that the scarcity of his symptoms is owing to the constant
exercise which he was obliged to take during the period of the proving.
w. huber's proving of thuja on his wife.
H.'s wife made two experiments with Thuja.
(28.) First proving, with dilutions.
From the 19th of April to the 18th of May, Mrs. H. swallowed 100
drops of the various dilutions, from the 30th to the 1st, at the same
time and in the same order as her husband, without experiencing any
other symptoms, except slight vertigo and some headache in the
forehead.
(29.) Second proving, with the tincture.
The second experiment was likewise instituted simultaneously with
that of her husband, from the 18th to the 28th of June, with this dif-
ference, that, whereas he took progressively increasing doses, she took
10 drops a day for ten days in succession.
The prover was but little affected by those doses. On the fifth day
after commencing the proving, several wart-shaped excrescences, of the
size of a poppy-seed, made their appearance on both hands, gradually
increasing during the proving, and amounting in number to sixteen.
At the conclusion of the proving they varied in size according to the
different periods when they had made their appearance. Their shape
was that of a truncated cone ; their surface was smooth, and they ap-
peared to be seated in the epidermis.*
A fortnight after concluding the proving of Thuja, the warts ceased
to grow. The largest warts were of the size of a small pea, and their
formerly smooth surface had become rough and split. The remainder
were smooth and of various sizes, according to their respective ages.
They remained in that condition until about the middle of August,
when the larger ones became depressed in the centre, and resembled a
little pit surrounded by an elevated ridge. This ridge disappeared
gradually, together with the wart. The smaller warts disappeared
without going through this process.
* Huber's wife had formerly been troubled with warts, and, when she com-
menced the proving, she had one on the dorsum of the left hand, which had been
in existence lor several years. — Mayrhofcr.
36 Thuja Occidentalis.
On the 10th of September eight warts still remained, and on the
11th of December (more than five months after the proving had been
concluded,) all the warts had disappeared except a small one on the
third joint of the left little finger.
(30.) iiuber's proving of thuja on three of his children.
Three of the children of Dr. H. likewise proved the dilutions of
Thuja, from the 30th down to the 1st; two boys, of five and ten years,
and a girl of seven. No symptoms were discovered in any of the
children, except warts of the above described shape on the hands, of
which the elder boy had six, the younger five, and the girl three.
On the 14th of September, after the results of the proving had been
sent in, new warts continued making their appearance in the elder boy,
and on the 11th of December he still had twenty-two warts of different
sizes ; while on that day the warts of the younger boy had all disap-
peared but one. No further information has been received in relation
to the three warts of the girl.
(31.) huber's proving of thuja on a female affected with
WARTS.
The prover is 40 years old, of a stout-make, middle-size, and san-
guine temperament. Her menses appeared early, she married at the age
of 20, and has five healthy children. Except during the periods of
pregnancy and lactation, her menses were very profuse for three or four
days ; her health was constantly good. Three years ago she was at-
tacked with horny warts, one on the tip of the left ring-finger, two in
the palm of the left hand, and one in the palm of the right hand ; they
troubled her a good deal in her domestic affairs ; while washing, either
in cold or warm water, they became cracked and exhibited deep painful
rhagades on the surface.
Being informed that she might possibly get rid of her warts by prov-
ing the Thuja, she consented to undertake it. From the 3d of May un-
til the 30th of June, she took six drops of the mother-tincture every
day, and from the 1st to the 26th of July, ten drops a day.
The prover living at a distance, H. could only see her occasionally,
and he recorded the following observations at those intervals.
May 11th. The prover complained of frequent attacks of vertigo and
diminished sleep. Her mood was anxious, and the menses, which ap-
peared on the 6th, were inconsiderable and lasted only one day.
19th. Her complaints were the same. The vertigo frequently made
its appearance when sitting or lying down ; during the day she fre-
quently experienced a transitory tremulousness over the whole body.
26th. The above-mentioned phenomena continued, especially the
anxiety. The woman thought she could not continue the drug, because
she had almost entirely lost her appetite, and suffered constantly from
a sweetish taste ; even streaks of blood were occasionally seen in the
Dr. W. Huberts Provings (31). 37
saliva, and the warts became still more painful. She consented, how-
ever, to continue the drug.
June 3d. The former symptoms continue. Moreover, wart-shaped
excrescences of the size of a poppy-seed were discovered on the dorsum
of either hand, six on the left, four on the right. In the daytime she
is frequently attacked with chilliness, feels very weak, and has a slight
leucorrhoeal discharge, which she never had before. The old, horny
warts are very painful when touched, or while she is at work, but the
new ones are painless.
10th. The chilliness has been almost constant since the 3d, the
prover has no appetite, is quite unwell, faint, debilitated as by fatigue,
without being able to state what ails her. The warts looked as if split
up, and exhibit deep, painful rhagades, especially while washing. To
her great dismay, the new, painless warts, became larger every day.
The leucorrhoea lasted until the 8th, when the menses made their ap-
pearance, which, however, lasted only a single dag, and consisted in
the discharge of a small clot of black blood of the size of a hazelnut.
On the 9th, the leucorrhoea re-appeared. It is but scanty, but obliges her
to wash herself frequently in the daytime. It is mild, yellow-green,
and leaves spots of a similar appearance on her linen.
16th. The leucorrhoea increases. Everyday she feels a pain as if
bruised, at times in the shoulders, at times in the thighs. When step-
ping she feels an ulcerative pain in the soles of the feet, and they sweat
constantly. The horny warts become more painful every day, and the
skin around them becomes slightly reddish. The new warts are pain-
less, almost as large as the old warts, of the shape of truncated cones,
have a smooth surface, and appear to be seated in the epidermis only.
Besides these warts, traces of new warts are perceived on the dorsa of
the hands and on the fingers.
26th. The pain in the shoulders and thighs ceased six days ago, the
ulcerative pain in the soles of the feet continues, the leucorrhoea and
the chilliness continue likewise. The painful old warts are still sur-
rounded with a red areola, and the rudimentary traces above mentioned
have been developed into ten new warts of the size of poppy-seeds.
30th. The ulcerative pains in the soles of the feet have ceased. The
other symptoms continue.
July 8 th. Having taken ten drops of the tincture every day, she has
felt worse, ever since the first dose. She complained of being faint,
chilly, anxious, and that she had lost her appetite. This condition
continued until the 7th, when the menses appeared, after which the
pains diminished. The menses lasted only one day, and consisted in
the discharge of three clots of black blood, of the size of a hazelnut.
The leucorrhoea continued after the menses.
18th. The last 10 drops had affected the prover very much. The
frequent chilliness with debility were now accompanied with difficult
breathing, short and hacking cough, and momentary palpitation of the
heart. These symptoms were especially troublesome in the daytime :
38 Thuja Occidentalis.
the nights were quiet : the old warts presented the same appearance as
before : the new ones (the first crop) assume an irregular shape, and
exhibit a rough surface. The most recent warts (the second crop) had
become somewhat larger, and traces are even perceived of a third crop.
The leucorrhcea continues, and the prover thinks she has become thin-
ner during the period of proving.
26 th. All the symptoms continue in an increased degree. The diffi-
culty of breathing and the feeling of anxiety attending it are especially
troublesome. The appetite is almost entirely wanting ; every meal
causes pressure at the stomach. The debility is worse. The prover
looks pale and sickly. Her dresses have become loose. There are
four sets of warts : the oldest are still surrounded with red areolae ;
the next have a rough surface and an irregular shape ; the smaller warts
of the second crop have smooth surfaces, and the shape of truncated
cones, and lastly the warts of the third crop, which are very small,
from the size of a poppy-seed to that of a millet-seed.
As she not unreasonably feared that continuing the experiment
would produce further trouble, and increase the number of her warts,
she put an end to the proving on the 26th of July.
All the symptoms continued with diminished violence until the 3d
of August. The warts remained unchanged, except that the last crop
seemed to have ceased to grow.
On the 7 th of August, the menses made their appearance ; they
were somewhat greater than the last time, and lasted a day and night.
On their appearance, all the' other symptoms diminished, even the old
warts became less painful, and the red areolae paler. All the recent
excrescences remained unchanged.
18th. Most of the symptoms had disappeared; she had a good
appetite, her breathing had again become easy and the leucorrhcea had
ceased. The old warts had become smaller and less painful, and they
ceased to crack during washing. The three subsequent crops continued
unchanged. By the 30th of August the health and good looks of the
prover had entirely returned. The old warts had ceased to be painful,
had much diminished in size, were even scarcely raised above the skin ;
several of the new warts had disappeared without leaving a trace, and
the remaining ones were much diminished.
Sept. 8th. The old warts had almost entirely disappeared, and the
recent warts likewise.
The menses, which appeared on the 5th of Sept., lasted three days,
and flowed as before the proving.
Dec. 11th. One hundred and thirty-eight days after the conclusion of
the provings, the old horny warts had disappeared without leaving
the least trace in the epidermis. Of the recent warts nothing was left
at that time except a very small trace of one only.
F. Lackner' s Proving (32). 39
E.
F. LACKNER's PROVING "WITH THE TINCTURE (32.)
Frederick Lackner, student of medicine, twenty-two years old, of a
melancholy choleric temperament and a robust constitution, had dysen-
tery when a boy, also scarlet-fever and measles, was frequently affected
with worms and toothache, and had a violent ophthalmia when he was
sixteen years old, which left a great disposition to congestion to the
head and eyes, continuing to the present time. For the last four years
L. has enjoyed excellent health.
1844, Oct. 10th. He commenced the proving of Thuja with 6 drops
of the tincture, which he took in the morning. They caused eructations,
colic towards noon, and diarrhoea.
11th. 8 drops had the same effect. 12th. 10 drops, after which the
colic became exceedingly painful; it diminished gradually after a
copious evacuation. In the hypogastrium the prover experienced a
sensation as of pressure, especially directly above the symphysis pubis.
13th and 14th. L. took 12 and 14 drops, and no medicine on the
15th. On all those days the colic was less, but the sensation of
pressure in the hypogastrium from within outwards remained the
same.
16th and 17th. 16 and 18 drops, the colic and diarrhoea increased.
18 th. 20 drops ; had slight colic and felt drowsy the whole day.
19th. 25 drops, after which he experienced a constant gurgling in
the bowels.
20th, 21st and 2 2d. 30, 35 and 38 drops, which increased the colic
and diarrhoea.
23d. 40 drops. After the lapse of two hours the colic became so
violent, that he was scarcely able to stand straight, and had to sit with
his trunk bent forward. These pains lasted upwards of an hour, and
diminished after a copious evacuation accompanied with emission of a
quantity of flatulence. In the evening the pains became again more
severe, without, however, reaching the former degree of violence. His
sleep was restless and full of dreams.
24th. No medicine was taken, and the colic abated and the sleep
became more quiet.
25th and 26th. 45 and 50 drops, which again brought on slight colic,
which was considerably increased on the 27 th, after taking 55 drops.
L. now discontinued the proving for three days. On the 28th
the colic kept increasing and disturbed even his sleep ; it was accom-
panied with distention of the abdomen and constipation. On the
29th in the morning he had eructations ; towards 10 o'clock great
nausea with accelerated pulse, debility of the limbs as from weariness,
and cold sweat over the whole body. This condition improved during
a walk, by the raising of a quantity of wind. The colic, on the con-
trary, increased until noon, but abated towards evening. In the morn-
ing and after dinner he had a copious fluid evacuation. The appetite
was less, the sleep restless and disturbed with dreams. On the 30th,
40 Thuja Occidentalis.
in the morning, he had a scanty liquid evacuation ; the colic was very
slight and the appetite diminished.
On the 31st of Oct. and on the 1st of Nov. he took 60 and 65
drops, which did not produce any new symptoms, hut on the 2d of
Nov., after taking 70 drops, he had again colic and diarrhoea, which
became so violent on the following day, after another dose of 75
drops, that he was scarcely able to stand straight at noon. While
driving home, the colic, which was now accompanied with headache
and chilliness, became almost intolerable. After it had lasted almost
an hour, it abated somewhat after a very copious liquid evacuation,
which was accompanied with copious emission of flatulence : but again
increased towards evening.
Nov. 8th. L. continued taking the Thuja, and, nevertheless, increased
the doses by five drops every day, so that at this date he took 100 drops.
The most constant symptom was the colic, which increased from
morning until noon, intermitted after dinner, but re-appeared in the
evening and continued until midnight ; this was accompanied with the
sensation of pressure in the hypogastric region.
9th. 110 drops. During the day he had colic; in the evening
burning in the eyelids and the sight was less distinct ; in the night
pain in the head and eyes, pressure in the pit of the stomach, and
hurried breathing. He did not sleep till towards morning, after
which the symptoms disappeared.
10th and 11th. 120 and 130 drops, after which he experienced a
burning in the eyelids with obscuration of sight ; the sleep was inter-
rupted and restless. The same symptoms appeared on the 12th, after
taking 140 drops. In the evening the pupils were dilated. On the
13th no medicine was taken; 150 drops, which were taken on the
14th, were not followed by any new symptoms.
loth. 160 drops. After dinner he suddenly felt a shrill ringing in
the right ear, which, after a few hours, as suddenly changed to a dull
buzzing and groaning, the latter sensations gradually changing to a
noise as of a bubbling liquid, which continued all night. In the even-
ing and night he emitted a large quantity of flatulence and yellowish
wine-colored urine ; his sleep was disturbed by voluptuous dreams ;
in the morning he felt excessively drowsy, and was loth to leave the
bed. No alvine evacuation.
16th. 170 drops. The whole day he emitted a quantity of flatu-
lence without any motion of the bowels ; his mood was especially
cheerful ; he slept quietly at night.
17th. 180 drops. These caused the emission of an excessive quan-
tity of flatulence day and night. In the morning he had a scanty
evacuation with some colic.
18th. 190 drops, after which he had a scanty papescent stool (after
dinner) and then a violent burning at the anus. In the evenino- he
had colic and emitted a quantity of flatulence.*
* The colic which is occasioned by Thuja seems to originate primarily from the
distention of the bowels produced by flatulence. — Mayrhofer.
F. Lackner > 8 Proving (32). 41
19th and 20th. 200 and 210 drops, which occasioned nothing but
colic and a liquid evacuation.
21st. 220 drops. These occasioned a papescent stool in the fore-
noon. In the evening, moderate colic, and, during the night, constant
desire to urinate and emission of a large quantity of light-yellow
urine. Every urination was followed by a violent burning pain in the
urethra, and in the fundus of the bladder. In the morning he had a
hard stool and soon after violent colic.
2 2d. 230 drops, after which the colic lasted all day, the desire to
urinate likewise; the pain after urinating was, however, less.
23d. 240 drops, after which he discontinued the drug until the 30th.
During this period of time he observed the following symptoms : every
day, after dinner, he had a papescent stool with emission of a quantity
of flatulence, hoarseness and secretion of mucus in the fauces obliging
him to spit ; obscuration of sight with dilatation of the -pupils and
burning of the eyelids.
30th. 150 drops, after which, he discontinued the drug until the 7th
of Dec. The same symptoms appeared as on the previous days, but in
a less degree, and they disappeared, finally, altogether.
Dec. 8th, 9th, 10th and 11th. 260, 270, 280 and 290 drops of the
t incture ; the only symptom occasioned by these doses, was a slight
o olic.
12th. 300 drops. At noon he felt a slight colic ; in the evening he
suddenly felt a violent pain in the whole abdomen, as if all the bowels
were pulled towards a point behind the umbilicus. This was accom-
panied with distention of the abdomen, headache and accelerated pulse.
This colic lasted six hours, and abated gradually after a liquid evacua-
tion accompanied by an emission of a large amount of flatulence.
13th. 310 drops. The colic continued until evening ; on the 14th,
after taking 320 drops, he experienced all day occasional shooting
stitches in the abdomen. Took no medicine on the 15th and 16th,
and had no symptoms.
From the 17th to the 24th of Dec. inclusive, L. took a dose daily,
increasing every dose by 10 drops, so that on the last day he took
400 drops.
The symptoms elicited by this prover were meagre and one-sided.
He was attacked with colic every day, noon and evening, which in-
creased from day to day, and became extremely violent on the 23d of
Dec. and on the 3d of November. The colic abated considerably on
the emission, during a walk, of a considerable quantity of flatulence
upwards and downwards, and after a copious liquid evacuation at
noon. In the afternoon and evening he occasionally suffered from
sticking, gurgling, rumbling and shifting of flatulence in the abdomen,
and he had a sleepless, restless night.
24th. These symptoms abated; on the two subsequent days when
L. took no medicine, he complained of nothing but debility.
27th and 28th. 410 and 420 drops did not occasion any new symp-
42 Thuja Occidentalis.
toms ; on the following days, 430, 440 and 450 drops occasioned no
other symptoms than the constant rumbling and shifting of flatulence
in the abdomen, accompanied with shooting stitches in all the parts
of the body.
Persuaded that the Thuja had been prevented from manifesting its
proper effects upon the organism by the rapid succession of large doses,
L. discontinued the proving for a few days, and even during the first
days of January, 1845, perceived traces of the last named symptoms.*
January 8th and 9th. No symptoms being any longer observed, L.
took 460 and 470 drops, without any results.
10th. 480 drops; two hours after taking the drug, he had eructa-
tions, desire to vomit, and a peculiar feeling of qualmishness in the pit
of the stomach ; these symptoms continued until midnight, and were
accompanied with constipation, restless sleep, and vivid dreams.
11th and 12th. 490 and 500 drops, which occasioned the following
symptoms : drawing and tearing in the pericranium, at times in the
region of the vertex, at times in that of the occiput ; one scanty stool
every day ; confused dreams about the most absurd things. On the
evening of the last day, burning and stinging in both eyes and eyelids,
with injection of the cornea; these symptoms continued on the 13th
after taking 510 drops.
14th and 15th no medicine was taken. On waking on the 14th, he
was for a long time unable to open his eyelids. They were painful and
closed again involuntarily. After rising he felt debilitated all over, es-
pecially in the upper arms and thighs ; clouds and streaks (muscce
volitantes) were hovering before his eyes the whole day, accompanied
with indistinctness of sight, which continued the next day.
16th and 17 th. 520 and 530 drops occasioned a warm feeling in
the region of the stomach; 540 drops, which he took on the 18th,
occasioned a feeling of qualmishness, eructations, and the emission of a
quantity of flatulence.
No medicine was taken from the 19th until the 6th of Feb. inclusive.
On the first day the region of the stomach was very sensitive even to
the least pressure, especially in the evening ; there was a frequent and
continuous rising of wind from the stomach, and continual emissions of
copious flatulence from the rectum. These symptoms gradually abated
on the following days, and finally ceased entirely.
Feb. 7th and 8th. 550 and 560 drops ; the only result obtained was
eructations tasting of resin, accompanied with aversion to the druo-
which became so invincible that he had to conclude his provings after
having taking 15,920 drops of the undiluted tincture in the space of
122 days.
* The development of the effects of a drug is most certainly prevented when the
doses taken are relatively so large as to excite vomiting, diarrhoea, profuse sweat or
enuresis ; by means of these processes the drug is carried out of the body and is
thus prevented from penetrating the organism and manifesting its physiological
action upon those parts of the organism to which it stands in physiological relation.
— Mayrhofer.
Dr. Landesmanri 's Provings (33). 43
This indefatigable prover deserved a better result : the. drug in him
principally affected the primae vise, producing violent flatulent colic,
diarrhoea, and enuresis, by which revulsions the development of the
specific effects of Thuja was prevented.
F.
Jacob Landesmann, chief physician to the battalion of Grenadiers,
under Major Blankardt, made two experiments upon himself with
Thuja.
(33.) First proving with dilutions.
The unquestionable effects which L. had experienced from a few
drops of the first dilution of Bryonia, induced him to commence the
proving of Thuja with the smallest doses of the higher dilutions, and to
descend by gentle degrees to the lower.
After he had discontinued taking Bryonia for three weeks, and had
felt free from any drug-symptoms for two, he took, from the 4th to the
20th of Sept., 1844, regularly every morning, one hour before a milk
breakfast, three globules moistened with the 27th dilution of Thuja,
(1 : 100 prepared by himself five years before).
Sept. 4th and 5th. L. remarked no change in his sensations.
6th. In the forenoon, drawing tearing in the right arm, lasting se-
veral hours.
7th. The same sensation.
8th. Drawing,, sticking pains in the right index and middle fingers.
9th. A renewal of the drawing tearing in the right arm, in the
morning ; later, at about half-past ten, debility and lameness in the
right forearm, and violent trembling of the right hand, in which the
veins swelled without any apparent cause. This appearance lasted half
an hour, and disappeared while writing.
10th. Violent itching on different parts of the skin, particularly on
the breast, with a sensation as if the skin at those spots was pierced
with many very fine needles, which irresistibly obliged him to scratch.
On the evening of the same day, there came on, without cause, a heavy
cold preceded by dulness of the head and frequent sneezing.
11th. At 10 in the morning, a sticking pain in the ring-finger of the
left hand ; towards noon, stinging itching on the breast again, and on
both sides of the neck, and at 9 in the evening, drawing pains in the
left shin-bone.
12th. A slight pain was observed in the right side of the pharynx,
extending to the ear, somewhat aggravated by swallowing.
13th. The morning pain in the neck had entirely disappeared, but
returned in the afternoon, with feeling of dryness and increased thirst,
and wholly vanished again in the evening.
The remaining days presented no new symptoms. It is particularly
to be remarked, however, that the catarrh was troublesome through
the whole of this proving, and had this peculiarity, that it often com-
44 Thuja Occidentalis.
pletely disappeared for hours together, and then suddenly returned
without cause, with renewed severity, and with much sneezing.
From the 20th to the 28th, L. took every mornino- six globules
moistened with the sixth dilution, which had no other effect than that
they seemed to sustain the still continuing catarrh.
From the 29th Sept. to the 3d Oct., L. took again the 27th dilution,
and five drops besides every morning, but without effect.
Oct. 4th, 5th, and 6th. He took every morning five, and from the
7 th to the 17th, ten drops of the sixth dilution. Whereupon, besides
the still continuing catarrh, the following symptoms appeared :
5th. In the afternoon, cutting pains in the vesica for some minutes.
6th. In the morning, sticking, cutting pains in the left side of the
neck, as far as the left ear, which soon disappeared again.
7th. In the afternoon, drawing pain in the left middle finger.
8th. Repeated drawings in the left great toe, and at night lascivious
dreams with a pollution.
From the 9th to the 12th, except the constant catarrh, no symp-
toms.
13th. Dryness in the throat; soreness of the breast, with aggravated
catarrh, and in the night confused lascivious dreams.
14th. In the morning and at noon, a feeling of stoppage in the left
ear, with diminished power of hearing, each time lasting several minutes.
15th. In the morning, distinct, violent stitches from the anus into
the region of the left iliac bone.
16th. At various times, drawings in the left little finger.
From the 18th to the 22d Oct., L. took, every morning, fifteen, and
from the 22d to the 29th, thirty drops of the first dilution.
18th. The catarrh, which had remitted, became worse with frequent
sneezing. Afterward on the same day in the afternoon, a sharp lan-
cinating pain in the left frontal eminence, and soon after, sharp tear-
ings in the inside of the right ankle.
19th. Were perceived at several times, tearings in the little finger of
the right hand, and in the evening dulness of the head in the forehead.
20th. Frequent quiverings of the lower lid of the left eye.
21st. Again, frequent quiverings of the same eyelid; further, draw-
ing in the little finger in the right hand, and restless sleep with lasci-
vious dreams.
The following days passed without symptoms. But on the 26th
frequent quiverings came on in the afternoon and evenino-, pulse-like
jerks in the muscles of the right arm, especially in the deltoid. L.
was, also, the whole day, causelessly excited and inclined to bo angry
contrary to all his previous habits.
28th. At about half past ten in the forenoon, while walking he was
attacked with such deadly hunger, that he came near fainting, and w T as
obliged, at a very unwonted time, to eat something in a neighborino-
tavern. This symptom made the more impression on him, as it was
repeated in the evening of the same and of the following day. He had
Dr. LandesmanrCs Provings (34). 45
likewise, in the right nostril, a feeling of soreness or ulceration, -which
was aggravated by pressure upon the ala, but disappeared on the fol-
lowing day.
29th. L. took forty drops of the first dilution, but was prevented by
circumstances from pursuing the experiment from that day. No fur-
ther symptoms developed themselves which could be attributed to the
drug. The catarrh lasted until the middle of December, and the
prover has much less hesitation in ascribing it to the power of the drug,
because a catarrh had never lasted him so long before.
(34.) Second proving, with the tincture.
Feb. 1st. L. began a new experiment with the tincture of Thuja, of
which he took on the first day ten drops and increased the dose daily
by five drops, so that on the 15th of the month he had reached eighty,
and had taken in the whole 675 drops.
Not the slightest change in his feelings followed any dose of the
tincture.* From this circumstance, the prover concluded that his sus-
ceptibility to the remedy was by this time exhausted, and in the con-
viction that continuing to take it in increasing doses would produce
conditional symptoms, depending more upon the quantity than the
quality of the drug, he discontinued the proving in order that he might
no longer defer the more grateful result of an experiment with a re-
medy more accordant with his constitution.
(35.) G.
Dr. and Prof. Liedbeck, from Upsala, aged 42, of a sanguineo-bilious
temperament and narrow build, often suffering from catarrhs and he-
morrhoids, made an experiment with Thuja during his residence in
Vienna.
1844, Sept. 14th. He took, at about five o'clock in the afternoon, a
teaspoonful of the undiluted tincture. Thereafter, eructations with the
taste of the remedy and, an hour later, transient pain in the forehead
and in the left side of the face, a sort of twitching.
15th. After having taken sixty drops in the morning; eructations
tasting of the drug, then a repeated transitory stitch in the left frontal
eminence, and a sensation of dryness in the mouth — after another sixty
drops taken the same afternoon, a gloomy, melancholy state of mind
came on, which was still apparent on waking next morning.
16th. Seventy drops ; followed by eructations, strong aversion to
meat, which had already been perceived on the preceding day, difficult
swallowing, without any apparent cause, in the throat, stitches in both
* We can render no satisfactory account whatever, why it is, nor under what
conditions it happens, that in certain cases attenuations produce more powerful effects
upon the organism than the concentrated drug, and in certain other cases, pre-
cisely the reverse occurs ; and so long as this veil is not lifted, so long will the con-
test about the superiority of the high and low potencies remain undecided. — Mayr-
hofer.
46 Thuja Occidentalis.
sides of the thorax under the mammae, both during respiration and
when not respiring. The melancholy frame of mind continued. These
symptoms disappeared in the course of the following day, excepting the
stitches in the thorax, which often returned and did not seem to be con-
nected with the respiration.
25th. L. took 140 drops of the tincture of Thuja. Eructations fol-
lowed, and a feeling as though perspiration was about to break out.
26th. Tbe same symptoms followed a like dose. It is to be ob-
served, that the prover thinks that he passed more urine during the
experiment than at other times.
The departure of our northern brother in the faith unfortunately
prevented the further prosecution of the experiment.
H.
Dr. Maschauer instituted two experiments upon himself with the
Thuja.
(36.) First proving \ with the tincture.
1844, Sept. 21st. M. began the proving with ten drops of the tinc-
ture taken early, fasting. He perceived no effects but an unpleasant
taste.
22d and 23d. Each day ten drops; followed in the afternoon of the
first day by rumbling in the abdomen with emission of flatulence, co-
pious limpid urine and constipation ; on the second day, scraping in
the throat and inclination to cough. In the afternoon, the uvula seem-
ed to be lengthened, and the tonsils were vividly reddened, but the
swallowing was not w T orse.
24th and 25th. Thirty drops ; on the first day dryness of the palate
with inclination to cough, sidelong stitch in the lower half of the left
breast ; in the evening aching in the forehead with failure of the sight
— at night frequent urination. On the following day, continued
scraping in the throat with frequent cough, the headache and increased
urination also persisted, and were accompanied by a stitch in the left
testicle.
26th. Forty drops. The scraping in the throat much less ; at noon,
a double stitch in the breast ; want of appetite with great thirst and
dryness of the mouth ; at night copious urine, with tickings in the
urethra.
27th. When nothing had been taken, restless sleep, interrupted by
straining cough ; the urine continued increased.
28th. M. took fifty drops, and discontinued the dose for two da vs.
Effects, nauseous taste; eructations with smell of Thuja; frequent
hawking with the sensation as if the throat w r ere sore, continuing the
whole three days. In the evening, headache in the vertex, remaining
until midnight ; tickings in the urethra when urinating ; restless
nights.
Dr. Maschauer's Proving (36). 47
Oct. 2d and 3d. M. took on each day 60 drops on an empty sto-
mach. On the first day frequent hawking with cough ; in the after-
noon stitches in the lower part of the left breast, and debility, with
feeling as if beaten in the limbs. On the second day, soon after taking
the dose : dryness of the tongue ; throughout the day much thirst and
itching in the anus ; in the evening considerable headache which lasted
until midnight ; constipation. On the third day, itching in the anus
passing into a severe burning after a hard evacuation ; scraping in the
throat compelling him to cough, accompanied by itching in the urethra.
During the whole three days frequent and copious urine, especially at
night.
4th and 5th, M. rested. The itching in the anus appeared at times
in both days, and the evacuations ceased.
6th. 70 drops. The itching in the anus and the hawking and
cough again became worse ; the latter with oppression of the chest,
which seemed somewhat to embarrass the breathing ; also, copious
urine, hard stool, and restless sleep.
7th and 8th. 80 drops each day. On the evening of the first day,
a repeated, violent stitch in the left side of the chest ; on both days,
frequent raising of mucus with cough and reddened tonsils without
pain ; disagreeable itchings in the urethra and anus.
9th. After taking 100 drops, lasting pressing headache in the fore-
head with burning in the eyes, which were pained by the light. Con-
tinuance of the itching in the anus and the redness of the tonsils :
copious urine, failure of an evacuation, (M. was accustomed to have a
regular passage every day in the morning,) and a restless night. On
the three following days, he took no medicine, and the above symp-
toms, except accasionally the itching in the anus, disappeared.
13th. M. took again 100 drops. In the afternoon, itching through
the whole urethra during urination, and headache on awaking after a
restless night.
14th. 120 drops. The headache continued all day. In the after-
noon, a violent stitch in the left side of the chest, increased by inspira-
tion. Afterward, a hard evacuation with subsequent burning in the
anus ; the urine was copious, rest good.
15th. 140 drops. Two hours after, a violent evacuation with belly-
ache and burning in the anus ; in the evening, headache in the fore-
head ; at night, another evacuation and rumbling in the abdomen ;
also, general debility and copious urine, with itchings in the urethra.
16th. 140 drops. Shifting of flatulence with constipation ; scrapings
in the throat with cough ; in the evening, headache followed by a rest-
less night. During the three following days, no medicine being taken,
the evacuations became again regular, but the urine remained increased,
and the sleep was restless.
20th. After taking 160 drops, no evacuation, but a strong urging
towards it, with itching in the emus and into the urethra ; the urine
still copious : in the evening, headache, which lasted until about mid-
night ; after that, quiet sleep.
48 Thuja Occidentalis.
21st. Another 160 drops, (taken fasting and diluted with water, as
was always done) ; swelling in the region of the stomach, diminished
by emissions of flatulence ; in the afternoon, a hard stool and itching
daring urination ; in the evening, a return of the headache. On the
two following days, no dose was taken and no symptoms were per-
ceived.
24th. 180 drops were followed by these symptoms : uneasiness in
the region of the stomach with eructations of the drug ; scrapings in
the throat with frequent cough ; in the afternoon, headache with burn-
ing in the right eye, which disappeared on repeatedly washing it with
cold water ; copious urine, especially at night.
25th. M. closed his proving of the tincture, with 200 drops. After
two hours, a sudden debility, with painful lassitude, with pain in the
calves of the legs ; then, an internal chill in the whole body, with dry
and hot skin, which compelled him to lie down. He could not, how-
ever, keep warm in bed, and the debility increased to such a degree
that he could with difficulty move his limbs. At about ten o'clock in
the evening this chill first began to disappear, merging in a dry and
burning heat, and towards morning, a sweat broke out over the whole
body. He had no appetite, much thirst, passed no urine during the
whole day, and had during the access of heat a full, quick pulse and
intolerable headache. On the morning of the following day, he passed
a small quantity of dark-red urine ; the sweat continued until noon,
and the prover could not leave his bed on account of his extreme
weakness. A chill came on again in the evening, followed by a sleep-
less night.
27th. The debility continued ; he had no appetite, his tongue was
furred, and he urinated copiously.
28th. For the first time, M. felt better, but could not bring himself
to continue taking the tincture of Thuja ; for the simple smell of the
drug disgusted and horrified him.
29th and 30th. The itching in the anus was again perceived and
the copious urine persisted.
Nov. 8th. The prover first considered the action of the, Thuja to be
exhausted, as all the vital functions were then favorably re-instated.
(37.) Second proving with the first three dilutions (10 : 90).
Forty days after the last dose of 200 drops, M. be^an his second
proving.
Dec. 5th. He took ten drops of the 3d dilution, and increased the
dose daily by ten drops until the 15th of the month, without notino-
the least variation in his ordinary sensations.
From the 16th to the 23d, M. tried daily ten drops, morning and
evening, of the second dilution — with a similar want of result. From
the 24th to the 27th, he took twice a day ten drops of the first dilution.
After doing this three days in succession, the well known itchin v in the
anus developed itself and was especially troublesome in the forenoon.
Dr. Maschauer's Proving (36). 49
28 th. After twice taking fifteen drops of the same dilution, a slight
stitch in the urethra, increased urinating at night, and dampness at the
anus.
30th. M. took in the morning 30, and in the evening 15 drops of
Thuja of the first dilution ; afterwards uneasiness in the stomach, eruc-
tations of wind, bitter taste ; in the evening, violent headache, lasting
until ten o'clock ; copious, limpid urine, itching and sweat on the
anus.
1845, Jan. 2d. He observed, after 30 drops, from time to time,
stitches in the urethra, with urgent desire to urinate, loss of appetite,
vertigo, and headache in the forehead in the evening.
From the 3d to the 10th, M. took daily 30 drops of the first dilution
in the morning, and 20 in the evening. The constant symptoms were ;
urgency to urinate, with stitches in the urethra and itchings in the
anus.
This very promising experiment was unfortunately broken off in
consequence of the death of a person nearly connected with the zealous
prover.
I (Dr. Mayrhofer) proved the arbor vita upon myself and on my
wife.
On myself I instituted four experiments.
(38.) First proving, with the first two dilutions.
I began the proving of Thuja with the second dilution, making no
change in my manner of life.
1844, Sept. 8th. At 3 o'clock in the afternoon, I took 50 drops
without experiencing the slightest change in my sensations ; 100 drops
taken early, fasting, on the 9th, produced no further effect, nor did 150
more taken in the evening of the same day, nor 200 drops taken on
the 10th.
I tried then, on the 11th, at 6 o'clock in the morning, 100, and in
the evening 200 drops of the first dilution, without observing any mor-
bid phenomena.
Second proving, with the tincture in increasing doses.
1844, Sept. 12th. The want of susceptibility of my tough system to
the power of the dilutions determined me to try the undiluted tincture,
of which, on this day, I took 50 drops morning and evening each, but
waited yet in vain for any signs of life in Thuja.
13th. After 100 drops taken early and fasting, I first perceived,
during the day : swelling of the hemorrhoidal veins, with tenesmus,
itching and burning in the anus. In the evening, on repeating the
50 Thuja Occidentalis.
100 drops, I had two slight passages, ending with discharge of mucus,
itching, and burning.
14th. In the morning 100, and in the evening 200 drops. The
itching and burning in the anus increased, and were especially trouble-
some in the evening after a stool. — During the night, more frequent
and copious urine than formerly, and, immediately after urinating, I
felt a renewed inclination, whereby a few drops were discharged with-
out pain.
15th. 200 drops, taken both morning and evening, produced no new
symptoms.
16th. At 6 in the morning, 300 drops. Immediately afterwards,
nauseous taste and confluence of much saliva in the mouth. After a
quarter of an hour, dull headache over the whole frontal region (lasting
an hour). At six in the evening, a stool, with subsequent burning in
the anus, and shortly after a reiterated discharge of mucus, attended
with very violent stitches in the rectum in the direction of a line from
the anus to the sacrum. As the stitches ceased, the itching and burn-
ing returned, and lasted until ten o'clock.
17th. 300 drops. Itching and burning in the anus remained the
prominent symptom, lasting till midnight and preventing sleep. Three
stools followed, ending always with discharge of mucus ; the urine
was plainly increased, and after urination the inclination returned,
attended with the voiding of a few drops more.
18th. At about six in the morning, 600 drops were taken in a glass
of water, with the following result : Eructations of the drug for some
hours, confluence of saliva in the mouth, headache in the frontal re-
gion, and in the evening three stools, with subsequent itching and
burning in the anus and irritating stitches up the rectum. On the
following day, on which I took no dose, I frequently felt flying stitches
under the right shoulder-blade, and in the evening had three stools with
the accustomed accompaniments.
As in the course of the 20th, the following day, I perceived no drug-
affections, I took 40*0 drops at about nine in the evening. Before mid-
night sleep was destroyed by the emission of much flatulence, by itch-
ing and burning in the anus, accompanied by flying stitches in the
rectum and by repeated urination ; sleep, however, came on after mid-
night, and on awaking I found myself better than I could have ex-
pected after a bad night. I took no medicine on the next three days ;
regularly every evening the itching and burning in the anus set in ;
every day also I had two stools ending with a discharge of mucus.
23d. In the evening, 500 drops. Increased warmth in the face with
dull confusion in the head (effect of the alcohol) ; unrefreshino- sleep
interrupted by terrible dreams (of the dead) and by frequent urination.
On the following morning dull confusion in the head with general de-
bility. Through the day flying drawing pains in various parts espe-
cially in the hands, and in the evening a return of the itching and
burning in the anus.
Dr. Mayrhofer's Provings (38). 51
From the 25th to the end of the month I ceased to take the drug,
and made the following observations : On the evening of the 26th,
three round red spots of the size of a lentil, which itched and obliged
me to scratch, appeared on the inner surface of the right forearm near
the wrist. The itching became burning when they were scratched.
On the following morning they had disappeared without leaving a
trace ; on the 28th, I remarked a painful tubercle of about the same
size in the neighborhood of the anus, on the raphe of the perinseum,
which likewise disappeared in a couple of days. Flying drawing, now
here, now there, and troublesome itching in the anus, especially in the
evening, developed themselves every day, gradually however, wearing off,
Oct. 1st. At five in the afternoon, 500 drops ; followed by nause?
eructations of the remedy and (after half an hour) itching and burniit
in the anus. During the night, discharge of much flatulence
copious urine ; at six in the morning of the following day an evacur
tion with burning in the anus ; through the day felt well.
2d. On taking 500 drops, the constant burning and itching in the
anus reappeared, and the night's rest was as usual disturbed by fre-
quent urination and restless dreams. On the following day, no other
symptoms were perceived except debility and occasional flying stitches
in the rectum.
4th. I took, at about three in the afternoon, another 500 drops.
In the evening dull confusion of the head and burning in the anus ;
on the following night abundant urine, much flatulence, and dreams.
On the following day I felt pretty well again ; while urinating, how-
ever, I made the unpleasant discovery that the glans penis was entirely
covered with a greenish-yellow, ill-smelling secretion, and after I had
cleansed it, I observed on the dorsum of the glans, near the hinder bor-
der, four tubercles about the size of a flaxseed, with a vesicle on the
summit, and in the sulcus, near the attachment of the foreskin, was a
small eroded spot, surrounded by a red circle, about the size of a lentil.
6th. Nevertheless, I again took 500 drops of the tincture ; upon
which the symptoms already described again appeared, and the tuber-
cles on the glans had increased by two. The urine, since the large
doses of Thuja, had become turbid, and, in cooling, deposited a flocky,
mucous cloud. Urination was performed without pain, but a sensation
was often experienced, while seated, as if the glans had been bruised.
7th. No new symptoms were developed by a fresh dose of 500
drops, except that the vesicles of the elevations before described were
broken, and left behind little painless erosions, surrounded by a red
margin, and yielding the secretion alluded to.
During the three following days no medicine was taken, and the
protuberances became flatter, the circle paler, and at last the sore spots
disappeared also. Pains, at one time drawing, at another tearing, were
repeatedly felt, especially in the extremities, for the most part while
at rest, but in the right tibia also while walking, so as to make me
limp.
52 Thuja Occidentalis.
11 tli. At three in the afternoon, 600 drops. Besides the usual phe-
nomena, I noticed on the following day, granular, elevated red spots
on the glans penis, which was uncommonly sensitive, and on the 13th
the sebaceous glands of the prepuce appeared swollen and inflamed y
hut, on the 14th, the inflamed spots were paler again, the clustered,
prominent tubercles flatter; and on the 15th the appearance of the
prepuce and glans was again natural.
16th. At three in the afternoon I drank 1000 drops in a pint of
water. Immediately afterwards, nausea with vomiturition and con-
fluence of saliva in the mouth. After an hour, headache in the frontal
region with heat in the cheeks ; and half an hour later, general feeling
as if beaten, with a chill over the whole body in so remarkable a de-
gree, that I was obliged to go to bed, although it was only six o'clock
in the evening. The night was disturbed by many dreams and frequent
urination. On the three following days, no medicine being taken, I
felt uncommonly debilitated. I was especially annoyed by the itching
and burning in the anus, attended by several violent stitches in the
rectum (particularly in the evening). I also had, at times, drawing
pains in the hands and feet, which still continued even after eight days,
growing, however, weaker and weaker. No change was perceptible in
the glans penis, but I felt a burning pain in the perinseurn, the raphe
of which was more prominent than usual, and one inch from the anus
a tubercle of the size of a pea appeared, which increased for three days,
became moist, smarted in walking, and then day by day became smaller
and disappeared in about ten days.
(40.) Third proving, likewise with the tincture.
Nov. 8th. After I had desisted for three weeks, and felt -myself pretty
free from the effects of the drug, I began a new proving, by taking 300
drops of the tincture at four o'clock in the afternoon ; whereupon the
well-known Thuja symptoms made their appearance, as transitory
drawing, perceptible now here, now there, itching and burning in the
anus, copious urine, sensitiveness of the glans, &c, &c.
9th. 300 drops in the evening. In the night, increased sexual de-
sire, which, during the whole course of the preceding proving, had been
rather diminished than exalted.
10th. On the following day, soon after waking, I was annoyed by
an itching, burning pain in the hollow below the os coccygis, lasting all
day. The same phenomena recurred on taking 300 drops in the even-
ing. Three days subsequently the glans became sensitive, and the
sebaceous glands of the prepuce swollen as before on the 12th of Octo-
ber. On the fourth day I remarked a red tubercle between the scrotum
and the right thigh ; violent itching in the hollow below the os coccy-
gis was again very troublesome, and the anus became as sensitive
after a slimy discharge, as though the skin were cracked and chapped
ihere.
Dr. Mayrhqfer's Provings (40). 53
19th. When most of the Thuja symptoms had ceased, I took at
about three o'clock in the afternoon 1200 drops of the tincture (in
weight one ounce and two scruples) in a pint of water. The effect of
this draught was at first the drunkenness induced by alcohol ; heat in
the head and face, uncertain gait, reeling of surrounding objects, &c.
In the evening, a general feeling as if beaten, which drove me to bed
at eight o'clock. Sleep was interrupted, as before, by dreams and//e-
quent occasion to urinate. On the following days, besides the occa-
sional drawing in the limbs, I was annoyed by most constant Thuja
symptoms, itching and burning in the anus with tenesmus, especially
in the evening.
23d. Deep-red spots showed themselves on the glans, and the inner
surface of the foreskin was inflamed and swollen.
24th. The fifth day after the large dose of Thuja, a slight burning
pain was perceived in the glans, which, on examining in the furrow be-
hind the corona, was entirely covered with a thin, yellowish, ill-smell-
ing secretion, on the removal of which two deep-red spots were dis-
covered which appeared to be eroded, and from which the fluid alluded
to transuded.
25th. The two spots had increased in size, run together, and were
covered with granular elevations ; the glans was rendered uncomforta-
ble, but urination was performed without pain.
26th. The whole furrow as far as the fraenulum was sore and cover-
ed with papilla; of the size of a poppyseed. The secretion from the
glans was very copious.
27th and 28th of the month, the secretion was diminished in quan-
tity, but some twelve or fifteen reddish excrescences arose on the hinder
border of the glans, the largest of which was about the size of a flax-
seed, and the inner surface of the prepuce was full of granular tuber-
cles. On the next day, the elevations on the glans disappeared, as
well as the sore spots in the furrow, with a steady diminution of the
purulent discharge ; the sebaceous glands of the prepuce remained,
nevertheless, for some time swollen and prominent.
(41.) Fourth proving with the oil of Thuja.
Dec. 1st. At about three in the afternoon, I took three drops of the
oil of Thuja on a lump of sugar ; the oil had been obtained (one drachm
from four pounds of leaves) by the distillation of the tender twigs of
the tree ; it tasted exceedingly sharp and caused eructations for several
hours. In the night frequent urination, with very hasty, incessant
urgency, and on the following day redness of the glans at the aperture
of the urethra. After taking ten drops of the oil in the evening, the
eructations continued into the night.
3d and 4th. A dull pain developed itself in the left testicle as
though it had been bruised, and was perceptible both when seated
54 Thuja Occidentalis.
and when walking. On the 6th an eroded spot appeared again in the
middle of the furrow of the glans, which discharged a pus-like fluid.
7 th and 8 th. The discharge from the glans had attained its former
height. The whole furrow was covered over with pus, so that it was
necessary to cleanse it often.
9th. After moderate use of wine, the condition was still worse. The
inner surface of the prepuce was sore in spots, highly inflamed at
the frsenulum, the glans was sensitive and painful when walking.
I was now content with this painful present, and closed my proving
of Thuja. The discharge from the glans was first entirely cured,
after several alternations of better and worse, at the end of four weeks.
Itching and burning in the anus lasted the longest, and was still felt
at times after the lapse of months.
I must here repeat the observation, that during the whole duration
of the experiments with Thuja (unica nocte exempta) the sexual im-
pulse was diminished even to indifference. According to the results
above detailed, the chief operation of Thuja is upon the genital and
urinary systems. It was especially in the parts under the influence of
the plexus pudendo-hcemorrhoidalis that its effects fastened them-
selves, and were produced in objective phenomena. Its influence on
the muscles was of very short duration in my case, and it left the
respiratory and digestive organs entirely undisturbed.
(42.) Proving of Thuja on my wife.
1845, June lYth. Maria Anna M., 35 years old, sanguineo-melan-
cholic temperament, tall and slender form, mother of six healthy child-
ren, began the proving of Thuja, four months after the birth of her
last child, by taking 200 drops of the second dilution. This was at
about three o'clock in the afternoon. She experienced no effect from
the dose, nor from another of 200 drops of the first dilution.
19th. In the afternoon, she took 30 drops of the tincture, and on
awaking next morning, complained of painful tension in the left side
of the neck, darting upwards to the occiput and dowmvards to the
scapula, and preventing her from turning her head. •
20th. On which day she took nothing, the tension seemed somewhat
to remit, but returned in greater severity on the 21st, after taking 40
drops of the tincture. In the evening also there came on a crushing
pain in the inner side of the left wrist, in the head of the radius, which
last was plainly swollen and painful to the touch.
22d. In the afternoon, she took 50 drops. In the evening she felt
tension in both knees and heels, especially when rising after being
long seated. The stiffness of the nape of the neck continued.
23d. The same symptoms continued on taking 60 drops. She com-
pared the tension in the knees and heels to a feeling as if the feet had
been rendered stiff by over exertion in walking. She took nothing on
the last days of June, and the tension in the nape of the neck and in
the knees and heels diminished, but did not altogether cease.
Dr. Mayrhoferh Provings (42). 55
July 1st. After a pause of eight days, she continued the proving, by
taking *70 drops of the tincture. The tension over the patellae and
in the heels (at the point of attachment of the tendo Achillis,) imme-
diately increased. The rest at night was good, and no change was
perceived in the urine or stools.
3d. 80 drops were taken in the afternoon as usual, upon which a
dull, stunning headache, in the frontal region and vertex, came on,
which, however, did not last long.
5th and 8th. Nothing new was produced by 90 and 100 drops.
The tension in the knees and heels continued, but Avas only troublesome
while walking, not while sitting ; the tension in the nape was still oc-
casionally sensible, especially in the morning.
9th and 10th. 120 and 140 drops of the tincture having been taken,
no new developments took place, and the prover, stiffened in neck and
feet, concluded her experiment.
12th. The menses appeared at their regular period, but were weaker
than ordinary.
The poverty of symptoms in this proving is worthy of remark in
connection with the uncommon duration of the phenomena which did
appear. The stiffness of the left side of the neck, and the tension over
the knees and in the heels, diminished only very slowly, often disap-
peared, and then suddenly set in again, and first completely vanished
at the expiration of three months.
K.
Dr. Reisinger instituted on himself three experiments with Thuja.
(43.) First proving with increasing doses of the tincture.
1844, Nov. 5th. Dr. R. took in the morning 10 drops of the tinc-
ture, and increased the dose daily until he arrived at 100 drops, which
he then repeated every other day, until the 10th December, without
experiencing the slightest influence. Various hindrances prevented
the prosecution of this experiment.
(44.) Second proving with the tincture, in massi/ve doses.
1845, March 1st. R. recommenced the proving of Thuja with 100
drops of the tincture, and added 100 drops every other day, so that on
the 15th the dose was 800 drops. The sole symptom which he as-
cribed to the drug, was a tolerably strong, jumping, sticking pain in a
hollow tooth of the left under jaw, which had never ached before.
This pain appeared only upon the day of taking the drug, and about
three to four hours after its administration. But this very probable
symptom of Thuja disappeared again under the subsequent remarkably
large doses.
56 Thuja Occidental-is.
15th. After taking 800 drops, R. perceived in the evening a slight
oppression of the chest, with inclination to cough.
17th, 19th, and 21st. 1000, 1200 and 1500 drops produced no
effect whatever.
R. now discontinued the doses for eight days, and waited, but in
vain, for the after effect of the remedy.
29th, 30th, and 31st. He took, each day, 1500 drops of the tincture,
and remarked afterwards, slight vertigo (effect of the alcohol), perpetual
eructations, dryness of the pharynx, frequent hawking up of mucus,
and pressing, tensive feeling in the lungs, that became more percepti-
ble and sticking on taking a deep inspiration. The other functions
remained normal.
April 1st. Encouraged by this impunity, R. took from the 1st to
the 5th of April, in daily increasing doses, 1600 to 2000 drops of the
tincture, without perceiving the slightest change in his sensations, ex-
cept a feeling of dulness and confusion in the head.
9th. R. drank at one draught two ounces of the tincture. Of the
subsequent symptoms, the increased warmth in the stomach and whole
frame, the vertigo, the headache in the whole frontal region, and the
violent thirst, are rather to be set to the account of the alcohol ; Thuja
will have the credit of the following ; swelling of the veins, especially
of the arm ; eructations of wind, smelling of the drug ; oppression of
the chest with some pain on inspiring ; frequent hawking up of a tough
mucus ; restless sleep with confused dreams, and excited sexual impulse.
(45.) Third proving with dilutions.
As was to have been expected, no results followed an experiment
instituted by R. with the first twelve dilutions (1 : 99). He began
with 100 drops of the first dilution, and took daily the same quantity
of the succeeding dilutions in regular order, closing his resultless ex-
periment with 100 drops of the twelfth. He had now taken some
25,000 drops of the Thuja tincture, and was well weary of it, but not
sick.
Dr. Reisinger's proving of Thuja confirms the opinion, that for the
production of a drug disease as well as for the origin of a natural sick-
ness, two_ conditions are necessary, a noxious influence, and a natural
susceptibility. _ Where the proper soil, the sensitiveness of the organism
to the special influence of the drug, is wanting, there no symptoms of
disease will spring up, even under the exhibition of full doses of the
remedy, and the scattered seed, instead of ripening into full sheaves
will barely bud, or at most give but a very sparing harvest.
Dr. Sterz's Provings (46). 57
L.
Dr. Sterz made two short experiments with Thuja.
(46.) First proving with the tincture.
1844, Oct. 13th. He took the tincture every forenoon between ten
and eleven o'clock, upon a lump of sugar. He began on the 13th
Oct., 1844, with 5 drops, took 10 on the 14th, and increased the dose
each day by ten drops, until, on the 19th, he took 60 drops, but per-
ceived not the slightest effects.
20th. An hour after taking 80 drops, a sensation of roughness in
the throat came on and lasted until midnight.
21st. 100 drops. Immediately after the dose, feeling of roughness
on the tongue, the hard palate, and in the throat ; at noon sensitive-
ness of the gums of the molares ; at seven in the evening, colic-like
pain in the hypogastrium and movings in the bowels as if preceding a
diarrhoea, which, indeed, came on very violently at half-past eight with
severe bellyache : the pains then remitted, but the hypogastrium re-
mained tender for several hours. His sleep was quiet after midnight,
and towards morning much flatulence was discharged, the throat was
still rough and the fauces dry. He was frequently obliged to hawk,
and throw off white, tough mucus. After ten o'clock in the forenoon
he took a fresh 100 drops, upon which, frequent eructations with
nausea ; at noon, dull confusion in the forehead, which disappeared at
midnight ; in the evening a copious evacuation, with discharge of
much flatulence. All the morbid sensations had vanished on the next
day after a quiet night's sleep.
(47.) Second proving with dilutions (10 : 90).
Dec. 7th, 8th, 9th, and 10th. No effects were perceived from 200
drops of the 1 5th dilution, (the dilutions were prepared with one part
of alcohol and four of distilled water,) taken daily, nor from the same
quantity of the 12th dilution taken on the 11th.
12th. S. took morning and evening 200 drops of the 12th. At
noon feeling of dryness on the palate, and the next day drawing in
both thumbs on awaking.
13 th. 400 drops of the 12th. Thereupon roughness of the palate
and drawing in the right thumb, which last continued all day.
14th. Nothing new was developed by 400 drops of the 8th dilution.
The drawing in the right thumb extended into the wrist-joint. On the
15th no dose was taken, and except dryness of the throat no symptoms
appeared.
16th. 400 drops of the 6th dilution, which were repeated three days
after, on the 19th; after which, scraping and roughness in the throat,
and drawing in the right knee.
58 Thuja Occidentalis.
After a pause of twenty-eight days, S. also experimented with the
4th and 2d dilutions.
1845, Jan. 16th, 18th, 19th, and 21st. He took 400 drops each
day of the 4th ; and on the 5th, 6th, 7th and 8th of February 200
drops of the 2d. The following weak symptoms appeared : feeling of
dryness in the throat, with frequent hawking and spitting of a tough
white mucus and confluence of much saliva into the mouth ; the taste
was injured by it, and the food tasted as if it had not salt enough.
M.
Dr. Wachtel proved Thuja only in the dilutions.
(48.) First proving with the 3d dilution (10 : 90).
1844, Dec. 10th. Our associate, so remarkably sensitive to the effects
of Thuja, began his proving by taking 30 drops of the 3d dilution
about an hour after breakfast. He observed, in the forenoon, a sudden
thrust from before backwards in the right half of the chest ; at noon,
complete loss of appetite ; in the afternoon, itching and biting in the
prepuce ; afterwards, tearing pressing in the upper part of the right
thigh and left arm, which greatly resembled the effects of Bryonia, with
this difference, that the pain produced by Thuja seized the middle of
the affected member, was confined to a small spot, and was mostly in
the muscles; while that produced by Bryonia seemed to prefer the
joints and tendons. In the evening, he perceived maddening (! Ed.)
twitching in the right frontal eminence. An hour later, this pain at-
tacked the right eyeball much more violently, but shortly disappeared,
leaving behind a sensibility of the eye to touch of the hand, which re-
mained a long while. The sleep of the following night was good ;
but immediately on waking, the same pain reestablished itself in the
right eye.
11th. 10 drops of the same dilution, producing a return of the chest
pain of the day before, but this time in the left half. Afterwards, an
unsatisfactory, hard stool, with subsequent itching and biting in the
anus. In the afternoon, drawing through the whole length of the
outer surface of the thigh (of which side ? M.) ; in the evening, pressing
pain in the frontal and occipital regions ; itching in the corona of the
glans when walking (for half an hour). His sleep was good and com-
fortable, with lively and pleasant dreams. Feeling of health on awak-
ing, except weariness and lameness in the feet. On the 12th, no
striking symptoms followed a repetition of a similar dose ; W. only
remarked in the middle of the left parietal bone a spot of the size of
a dime, sensitive to the touch, and a drawing from the crest of the
right iliac bone to the upper part of the thigh.
13th. Pressing in the occiput was the only symptom after taking
10 drops of the 3d dilution. On the 14th, after a similar dose, pressing
m the forehead, lasting all day.
Dr. WachteVs Provings (48). 59
W. now discontinued the Thuja from the 15th December, 1844,
until the 7th January, 1845, inclusive, in order to see how long the
effects of the drug would continue ; and acknowledges his astonishment
at the duration of its action. During this time, he observed the follow-
ing symptoms :
16th. Violent drawing and pressing in the sacral region for two
hours in the forenoon. On the 16th, while writing, drawing pressing
in the right thumb (for five or six minutes) ; then in the index, later in
the middle, and finally in the little finger. In the afternoon, the same
sort of pain appeared in the left arm, shifted then to the upper part of
the thigh of the same side, soon after appeared in both the mastoid
processes of the temporal bones, then in the frontal eminences, where
the pain took more of a digging-twitching character, and finally reap-
peared in the extremities. This wandering about of the pains con-
tinued through the following day. On the 18th, for several hours in
the forenoon, the pain remained in the neighborhood of the left wrist ;
and during the whole afternoon, in the upper part of the left thigh.
19th. While lying down, the pressing in the sacrum was fixed in
the same spot for a whole hour. It was diminished and disappeared
on motion ; but afterwards appeared while lying in bed, in the lower
part of the left thigh, in the same spot where it had already appeared
once before. The prover remarked this day, on the edge of the upper
lip, two small, dark -red, burning spots, of the size of a lentil ; on which,
during the three following days, little elevations were developed, which
dried up and fell off. Later, two new spots appeared, which ran the
same course. He observed, in addition, feeling of stiffness on the left
side of the nape of the neck, which had been already perceived during
the first days of the experiment, but had been attributed from the be-
ginning, by the prover, to an uncomfortable position in bed.
24th and 25th. W. was often tormented by a very painful tearing
drawing in the left side of the chest, in the neighborhood of the fifth
and sixth ribs. This pain appeared when standing and sitting, disap-
peared when moving, and was rather diminished than increased by a
deep inspiration.
26th. Crawling drawing in the left zygoma, which left behind for a
long time a feeling of dulness. This symptom appeared again on the
27th, on the same, and afterwards on the right side. In the evening,
drawing tearing in the mastoid process of the left temporal bone, and
then in both eyeballs, where the pain ceased.
28th. The prover was annoyed through the whole day with a crawl-
ing, pressive pain in the left side of the sternum, which was confined
to a spot about the size of a dollar, remained the same in rest or mo-
tion, and finally left the feeling as though the spot was sore.
After three weeks, isolated symptoms were still perceived. The
pains were, for the most part, drawing, tearing or crawling, seldom
pressing, and least of all, sticking. They were mostly confined to a
small s])ot, seldom continued long, frequently changed their location,
and came on distinctly when at rest as well as during motion.
60 Thuja Occidentalis.
(49.) Second proving with the 12th dilution.
1845, Jan. 8th. After W. had almost ceased to perceive the symp-
toms produced by the proving of the 3d dilution, he took, at seven
o'clock in the morning of this day, three ounces of the 12th dilution.
An horn- and a half afterwards appeared (weakly marked) the charac-
teristic tearing drawing pains, sometimes in the frontal eminences and
in the occipital protuberances, sometimes in the middle of the left arm
and thigh (only when at rest). The crawling and drawing in both
zygomata, and in the left upper maxillary bone, came on instantaneous-
ly, and disappeared again as rapidly as it had appeared.
9th. Rather violent drawing in the right shoulder, and later, with-
out the slightest cause, cutting and griping in the left side of the
abdomen.
10th. No abnormal sensation was perceived; but on the 11th, ex-
traordinarily violent tearing in the left concha, and soon after in the
left eye, which ended with a darting stitch through the middle of the
eyeball. Copious urine also came on.
12th. The prover remarked in the region of the heart a small spot,
sensitive to the touch, with pain, as if it were sore, and on the follow-
ing day a similar spot immediately upon the vertex, upon which the
skin was somewhat reddened. At ten o'clock he went to bed in good
health, but after half an hour was suddenly seized with anxiety — after
which a slight perspiration broke out ; whereupon he fell asleep, but
continually started up again. Finally, drawing pains in the arms and
feet, and especially in the small of the back, came on. These having
ceased, he had quiet sleep till morning.
14th. W. found himself tolerably well ; only general weakness and
frequent accesses of drawing pains in different parts of the body annoy-
ed him. In the evening, the general debility increased, and he was
obliged to go to bed at seven o'clock. After some minutes his feet
became as cold as ice — he became again anxious. It was a very
striking symptom that in no position of the body, whether sitting or
lying, could he feel the pulsation of his heart. Slight shiverings,
which spread themselves by little and little over the whole body, came
on. At last, after a quarter of an hour, he experienced a trembling of
the heart — after which a general sweat broke out, so that in the
course of a minute the whole body was wet. This was followed by
dozing for an hour, unrefreshing, and disturbed by frequent starting
and horrible images. When he awoke from this, he was tormented
with drawing and tearing pains in the hands and feet, and when
these last suddenly disappeared, the anxiety and heart trembling re-
turned. It was only at the expiration of a quarter of an hour that his
heart again beat regularly ; but then drawing tearing pains in the
epigastrium, in the hypochondria, on the chest, but worst in the small of
the back, came on, ending in a slight perspiration, and finally in sleep.
Dr. WacliteVs Provings (49). 61
On awaking, W. was very weak, and every part of his body felt as
though it had been' bruised ; the head, however, was free from pain ;
the weariness, too, nearly disappeared in the course of the day.
15th. The prover went to bed later than usual. After he bad
lain quietly for a quarter of an hour his feet began again to become
cold, anxiety again came on, and in an instant, in place of the regular
beat, he felt a trembling of the heart. The sweat that then broke out
was interrupted by the prover's being called to a patient : on his return,
at the expiration of an hour, he slept tolerably well until morning.
16th. During the day drawing pains, now here, now there ; weari-
ness, with apparent loss of sensation in tbe limbs ; in the evening, after
lying down, cold feet again, with anxiety and palpitation, but less in
amount and of shorter duration.
Isolated symptoms were still remarked by the observant prover, six
weeks after the three ounces of the 12th dilution had been taken. The
following were daily visitors : the drawing pains in the hands and
feet, in the sacral region, and between the shoulders. The crawling
drawing in the zygomata, and the tearing in the occipital protube-
rances and in the petrous portion of the temporal bone were oftenest
perceived. No chest or abdominal symptoms appeared. But tvartliJce
excrescences frequently appeared on the back of the right hand,* on
the chin and other places. A furunculus, behind the right ear espe-
cially, continued a long while, and formed a scab, from which exuded a
glutinous moisture. This soon dried and fell off, when another formed ;
it was sensitive to the touch, and lasted four whole weeks.
Finally, W. repeats the observation, that the symptoms of Thuja
came on almost exclusively during rest, remained but a little while, and
were either rendered worse or caused to break out afresh, by the use
of spirituous liquors, except the customary beer.
This interesting result authorizes the conclusion, that individual sus-
ceptibility for a particular remedy plays a very important part in the
proving of drugs. While Reisinger's constitution, unsusceptible to
the influences of Thuja, remained almost unmoved by massive doses,
that of Wachter, especially subject to Thuja, produced with the smallest
doses the most abundant harvest of symptoms.
N.
Dr. Watzke instituted four experiments with Thuja, and of all the
drugs which he has assisted in proving, Thuja seems to have found the
least sensibility to its specific effects in him. He experienced no regu-
lar drug sickness, although isolated Thuja symptoms were clearly de-
veloped.
* These excrescences deserved a fuller description. — Ed. Aust. Journal.
62 Thuja Occidentalis.
(50.) First proving with dilutions gradually descending.
1844, Nov. 26th. and 27th. " I took," says W., " on these days, twice
in the forenoon, six drops of the 12th dilution, and during the two
following days the same dose in like manner of the 9th, and observed
a strict diet. Whether the symptoms which then appeared were cer-
tainly produced by the Thuja or not, I do not know ; but of this I am
confident, that they were such as I had never before experienced, and
such as almost constantly returned when I subsequently experimented
with larger doses of the drug.
" There appeared, especially during the time of proving, repeated,
short, dry cough, without throat symptoms or pain in the chest. The
hypogastrium appeared the whole time somewhat inflated and sensi-
tive to pressure, and even to the jar of the foot on the ground. It
seemed to me as if I perceived the vesica to be larger, and I was
obliged to urinate oftener than usual ; but I had neither pains in the
urethra, nor was the urine at all changed.
" From the 2d to the 14th December, I took nearly every day a
dose of Thuja; until the 6th, six drops of the 9th; until the 10th,
six drops of the 6th ; and on the 13th and 14th, six drops of the third
dilution.
" Although during this time I did not altogether observe a strict
diet, still some certain symptoms of Thuja manifested the working of
the drug ; certain, because they were renewed with renewed intensity
under the larger doses.
" These symptoms were, dry cough, pain in the patellae, frequently
returning whether sitting or walking ; a twitching as if a tendon
were slowly drawn out and then suffered to return ; a similar pain
while sleeping ; the outer malleolus of the right foot was painful while
walking, as if after a false step ; circumscribed pain in the inner side of
the thigh, as if after a long walk ; swelling in the region of the hypo-
gastrium with frequent urgency to urinate.
(51.) Second proving with small increasing doses of the
tincture.
" From the 19th December, 1844, to the 2d January, 1845, without
changing my ordinary mode of life, which was not confined to a very
severe diet, I took, at about noon of every other day, a dose of the tinc-
ture of Thuja, beginning with 10 drops, and increasing it each time by
10, until, on the last named day, I arrived at 80 drops.
" The abnormal sensations which I experienced during the duration
of this experiment, were the following : contractive pain in the right
temple, pretty severe, often returning and always lasting several seconds •
pressure in the right eyeball ; biting in the corner of the rio-ht eye
once at about five o'clock in the evening (without any cause affecting
the eyes), the surrounding objects, which I wished to regard, suddenly
Br. WatzJce's Provings (51). 63
swam before my eyes ; I could not see clearly, much less read. This
lasted nearly a quarter of an hour. Sensitiveness of isolated spots on
the thorax ; feeling of weight, and frequent cramp-like constriction in
the chest ; dry cough, increasing in a direct ratio with the duration of
the experiment, becoming constantly more troublesome, and finally
obliging me to lay aside the proving for a while ; sensitiveness and
feeling of inflation in the region of the vesica with frequent urgency
to urinate ; violent itching in distinct points on the inner side of the
thigh and on the parts of the genitals covered with hair ; sensibility
of the glans and darting stitches through it ; remarkable indifference
to the opposite sex ; several times, on awaking, drawing pain in the
great toe : a feeling in the little toe as if the skin were lacerated in
spots ; weariness of the lower limbs ; especially remarked in the lower
part of the thigh."
(52.) Third proving with steady doses of the tincture.
" From the 16th to and including the 20th January, I took daily
100 drops of the tincture without noticing any new symptoms ; those
developed under the previous proving again appeared with less violence,
except the dry, frequently returning cough, which rendered me so
anxious about my health that I was induced to discontinue the experi-
ment."
(53.) Fourth proving with large increasing doses of the
tincture.
Feb. 5th. I took 150 drops of the tincture; on the 6th, 300; on
the 7th, 450 ; on the 8th, 600 ; on the 9th, 700 ; on the 10th, 900 :
each time between ten and eleven o'clock in the forenoon.
" These doses produced nothing new ; they simply caused the most
of the symptoms developed by the second experiment to return, more
markedly, and with greater force. The last dose of 900 drops was fol-
lowed, during the whole afternoon, by frequent eructations of food with
the taste of the drug, and several times by violent, nearly watery, but
painless diarrhoea.
" Were these last two symptoms the result of accident ? or was the
organism so loaded with matter incapable of being assimilated by means
of the previous large doses, that it was obliged to get rid of it by the
shortest route ? and had it already by that means lost the capability of
further developing in itself the characteristic symptoms of Thuja ? "
(54.) Let the last proving reply to these queries !
Feb. 25th. I took in the forenoon two, and on the 27th three table,
spoons (about 1350 drops) of the tincture, at the same time observing
a strict diet.
64. Thuja Occidentalis.
" If these enormous doses gave me no drug disease regularly classi-
fied in any nosographic system, they at least produced in me the firm
conviction, that I could be very regularly and earnestly sick on taking
the medicament in that quantity. The goal, which I had proposed to
myself in this experiment, lay now at last in view ! Why did I not, then,
attain it ? I confess, I had not the courage for it. The energetic attack
which the drug had already made upon my thoracic organs, frightened
me back. Already had my first experiment with the dilutions pointed
out to me this unpleasant tendency of Thuja, although but slightly, and
I found it advisable to break off the second and third provings almost
from the beginning.
" The somewhat numerous symptoms that constitute my last proving
began to appear for the most part some hours after the dose, and con-
fined themselves principally to the first twenty-four or forty-eight hours ;
but nevertheless, they did not run an acute course, nor vanish, like
meteors, after a single appearance, but returned separately during the
period of from 8 to 14 days. They seemed to have a chronic charac-
ter, and a marked, though irregular periodicity.
" It was more especially upon the thoracic organs, as in the former
provings, on the muscles, the head, especially the occiput, and upon
the organs of generation, that the Thuja exerted its influence. The
peculiarity of the muscular pains was, that they generally affected the
middle instead of the tendinous portions of the muscle. Most of the
symptoms came on during rest, many of them on waking in the
morning.
" To prevent a tedious and unnecessary repetition, I confine myself
to a description of one day, the 27 th of February, which was one of
the richest in symptoms. At 11 o'clock in the forenoon, I had taken
three tablespoonfuls of the tincture.
" Immediately after the exhibition of the dose, the head felt cloudy ;
I felt my spirits excited and became lively and loquacious (effect of the
alcohol ?). Soon I perceived a slow-drawing, sometimes darting pain
in the right half of the face, from the temple to the teeth ; then the
whole became sensitive, and increased in sensitiveness with the subse-
quent symptoms, in the course of the afternoon. The occiput was ex-
ternally warmer to the touch in a particular spot, corresponding with
which I felt heat and pressure in the brain. At times dull stitches ran
through the brain, generally in the direction of the eyebrows, and from
the eyeball to the occiput.
" The cliest smarted internally, as if sore, especially during the
dry cough which appeared from time to time. In some spots I had
the feeling, as if the thorax from without, and the corresponding
portions of the lungs from within, were strongly and durably con-
stricted ; a feeling which returned frequently and strongly on the fol-
lowing days, especially during rest, induced frequent deep "sighino-, and
annoyed me not a little.
" There were spots here and there on the thorax and extremities
Dr. WatzkVs Provings. (54.) 65
painful as if from a thrust and especially during movement. In the
other spots I perceived a stitch, leaving behind an itching, as if they
had been bitten by fleas or ants ; in the forearm several times a cours-
ing and gurgling, as of single drops of blood rolling one after another.
I had frequently, for a minute at a time, a pain which in the axilla,
in the dorsum of the foot, and on various points of the external chest,
was pinching and pressing ; in the patellae and heels was stinging, and
in the external ear compressing.
" Violent twitching came on inisolated muscular parts, which was
strongest in the middle of the upper part of the right thigh and of the
left arm. In the ends of the fingers and toes, the twitching was finer
and more transient. This muscular twitching was frequently repeated
on the following days in different parts, and was one of the most trou-
blesome symptoms; for example, it still came on on the 13th of March,
and lasted for almost ten minutes in the chin.
" The stinging pain in the heel often returned, and was especially
troublesome in walking, (for a quarter of an hour.) The inner side of
the upper thigh and the parts of the genital organs covered with hair,
were very unpleasantly affected with itching and scraping, frequently
lasting from 5 to 10 minutes. Frequent stitches darted through the
glans, and the whole member, especially the glans, was constantly sensi-
tive. An uncomfortable sensation of fulness in the region of the blad-
der forced me to frequent urination ; the quantity of urine did not seem
increased, and its quality was perfectly normal. My digestion and
evacuation seem to have been left nearly or quite undisturbed. The
symptoms of the fourth proving, ( eructations of food and diarrhoea,)
must be considered as the result of accident.*
" The most lasting and most troublesome symptoms in my case, as
may be gathered from the foregoing account, were those which affected
the muscles and the chest. The dry cough, the constriction in spots
on the thorax and in the corresponding parts of the lungs, (frequently
returning, very irritating and annoying, compelling frequent deep in-
spirations and ameliorated by wine and beer,) first entirely disappeared
in the course of about eight weeks. The striking indifference to sexual
intercourse, by no means customary to me, continued during the whole
experiment, and, in fact, still longer."
0.
Dr. Wurmb instituted five experiments with Thuja ; four with the
tincture, and one with dilutions.
* Although Thuja has produced gastric symptoms in various provers after the
exhibition of large doses, yet, it must be considered as established as the general
result of all the experiments, that gastric affections are the effects not of the quality
but of the quantity of the drug ; effects, which may result from the administration
of any of the remedies in enormous doses. — Mayrhofer.
66 Tliuja Occidentalis.
(55.) First proving with small doses of the tincture.
1844, Sept. W. took, from the 17th, until and including the 21st, at
about 5 o'clock in the evening of each day, a coffee spoonful of the
tincture of Thuja; omitted it on the 22d; took the same dose at the
same hour on the two following days ; omitted it on the 25th ; and
from the 26th to, and including the 30th, again repeated it. The
following were the results.
18th. In the morning after urinating, burning in the urethra ; very
painful stitches from the urethra to the anus ; pressing in the region
of the neck of the bladder, with urgency to urinate. These feelings,
which the prover thought similar to those usually perceived at the
beginning of a clap, or after drinking new beer, lasted about twenty
minutes.
19th. Soon after the dose : tearing in the outside of the right ankle ;
then in the left elbow ; then drawing in the inner side of the upper
thigh, and finally tearing in the second joint of the right thumb. On
the 20th, soon after dinner, violent pressing in the left temple, which
continued all the evening, but in a less degree. During the proving,
the stools were softened, more copious, and took place from two to three
times a day.
(56.) Second proving with levrger doses of the tincture.
Oct. After a cessation of eight days W. took from the 8th to and
including the 14th, at five o'clock in the evening of each day, two coffee
spoonfuls of the tincture ; with the following result :
11th. Soon after the dose, feeling of roughness in the throat, lasting
some hours ; pressing in the right side of the chest, particularly notice-
able when breathing deeply, and when bending the body ; at seven in
the evening, drawing in the first joint of the right thumb, especially
during rest, instantly disappearing on moving the finger, and returning
as quickly on the cessation of the motion. This symptom continued
nearly an hour ; several times drawing in the third joint of the right
ring finger, and pressing to the left under the short ribs.
1 2th. The pressing pain appeared at the lower extremity of the right
side of the chest, after getting up ; it was somewhat violent at first, but
decreased very much during the day, without, however, entirely disap-
pearing. In the morning a very copious soft stool. In the evening,
on going out, after taking the drug, vertigo, drawing in the inner
surface of the right thigh, in the right knee, in the right calf, in the
bend of the elbow, in both popliteal spaces, especially the left. The
feeling of roughness in the throat was less than the day before.
13th and 14th. The sexual impulse was exceedingly importunate (with-
out any known cause). He thinks he passed more urine than usual.
15th. Frequent, and on every occasion -copious urination.
1 6th. The prominences of the right elbow were painful as if after a
severe knock, and this feeling did not entirely disappear until the 18th.
Dr. WurmVs Provings. (57.) 67
(57.) Third proving with large doses.
Oct. From the 20th to the 30th, W. took daily at nine in the morn-
ing, and five in the evening, two coffee spoonfuls of the tincture, and
observed as follows: On the 2 2d, in the morning, after getting up,
painful drawing in the second joint of the left thumb, (only during rest)
for about two hours. The same feeling, but not lasting, and much
weaker, appeared in the course of the forenoon, in almost all the finger
joints (but only during rest). For an instant, this drawing appeared
in the inner side of the left foot, as far as the sole. In the morning he
had the usual, and at eleven o'clock a papescent, stool. At six in the
evening, sudden drawing on the inner side of the left foot in the
metatarsus.
23d. No evacuation. In the evening, before going to sleep, drawing
in the left side of the neck. Restless night. He awoke at two o'clock,
and for an hour could not go to sleep ; then fell into a sleep which was
interrupted by frequent waking. He had besides a feeling of stoppage
in the right nostril, with frequent sneezing and chilly feeling in the feet,
which were externally warm to the touch.
24th. Immediately after getting up, a very troublesome drawing in
the left side of the neck and in the left shoulder, which only disappeared
in the afternoon.
At ten o'clock in the forenoon, drawing in the right heel, and half
an hour later, in the right index finger (disappearing instantly on move-
ment). The symptoms of the nose continued, with dull confusion in the
head. As W., according to his own observations, is but little sensible
to changes of temperature, and can trace no cause for this cold, he thinks
that these symptoms must be ascribed to Thuja.*
25th. 'ihe cold, with its accompaniments, sneezing, dull confusion in
the head, &c, continued. At about eleven in the day, transient draw-
ing in the index finger. Two hours subsequently, a similar drawing in
the left superior maxillary bone. At eight in the evening, troublesome
drawing in the left side of the hypogastrium (for a couple of minutes),
which spot was also painful to the touch.
26th. The catarrh is still present, only somewhat diminished in degree.
In the forenoon, sudden drawing in the left thumb and right little
finger (immediately dissappearing on movement and as quickly return-
ing in lest). At about ten in the forenoon, drawing in the hypogas-
trium on the left side, and tenderness on pressure. At about two in
the afternoon, troublesome clawing in the sternum, frequent short dry
cough, and increased discharge of urine. Frequent waking at night ;
towards morning, a pollution.
2 7th. On rising, drawing in the right thumb ; at ten in the forenoon,
drawing and pressing in the hypogastrium, on the left side, particularly
when touching it ; during the day, drawing, now here, now there, and
* It is certainly a property of Thuja, for the catarrh came on in the same way
wilh several of the provers. — Mayrhofer.
68 Thuja Occidentalis.
frequent hacking cough ; in the afternoon, drawing in the right arm
and forearm ; towards evening, painful drawing in the right great toe ;
at six in the evening, pressing in the middle of the sternum.
28th. Perfect health.
29th. Immediately after the dose, drawing in the lower incisors ;
about eleven, drawing in the right thumb; at five in the afternoon,
drawing in the left superior maxillary bone ; in the evening, feeling of
roughness in the throat and frequent short, dry cough.
30th. In the forenoon, drawing in the right superior maxillary bone,
in the inner side of the left forearm, and in the fingers of the right hand ;
feeling of roughness in the throat, and frequent dry, hacking cough.
The catarrh, which had vanished, showed itself anew by an increased
secretion of mucus from the nose. Copious urine.
31st. Increased urination : the catarrh worse.
Nov. 1st. In the morning, a loose stool, and after it a troublesome
pressing in the anus, which remained the whole day. The catarrh
became very severe, and one or the other nostril was almost constantly
obstructed. At three in the afternoon, sneezing, succeeded by very
violent sticking in the lower part of the right lung, which lasted until
eleven in the evening, when, although very severe before, it disappeared
at once. This sticking was greatly aggravated by sneezing, deep
breathing, and coughing (but not by movement). Pain, as if the parts
were sore, in the region of the ribs on touching them. At four in the
afternoon, drawing in the fingers of the right hand, and afterwards in
the right elbow.
2d. Drawing in the right calf the whole day. The catarrh reduced
to a minimum. At four in the afternoon a hard, scanty stool, and
pressing and itching in the anus for almost the whole evening.
3d. The running from the nose is again pretty copious ; frequent
sneezing ; at about four in the afternoon, sneezing, and then some pain-
ful stiches in the side of the chest, within.
4th. At six in the morning, very severe stitches in the lower part of
the right side of the chest ; about five in the afternoon, drawing tearing
in the right knee.
(58.) Fourth, proving with large doses.
Dec. From the 7th to the 14th, W. took every day at about 9 in the
morning, a tablespoonful of the tincture. — Effects :
7th. A pollution in the night, and after, a troublesome burning in the
urethra.
9th. Want of appetite, especially in the evening. On the 10th, a pol-
lution in the night.
11th. Feeling of roughness in the throat, which soon went off- then
for an hour, a feeling in the throat as if there were a painless tumor
there. At four in the afternoon, a papescent stool, and trausient draw-
ings often flitted about, now here, now there, especially in the upper
part of the thigh. Urine increased.
Dr. WurmVs Provings. (59.) 69
12th. Pressing in the left breast, after the sensation in the lower lobes
of the lung, especially when breathing deeply — frequent urination ; no
evacuation.
13th. Chills, even in the warm room; in the evening, well; no
evacuation.
14th. On waking in the morning, drawing in the left side of the
neck ; then drawing in the upper part of the left thigh (lasting two
minutes and rendering walking painful). Two stools followed, one hard
and unsatisfactory, afterwards another papescent, and which left behind
a long continuing burning in the anus.
15th. In the forenoon, three papescent stools (at six, nine, and eleven
o'clock.) Dinner nauseated him. Chills even in the warm room, and
apprehension of becoming sick. At six in the evening these symptoms
vanished, and the feeling of health was restored.
16th. Sudden drawing here and there, especially in the fingers of the
right hand ; no evacuation ; at four o'clock in the night a pollution.
17th. Sudden drawing in the limbs.
18th. In the morning, a hard, unsatisfactoiy evacuation; drawing in
the limbs — at one o'clock, feeling of dryness and sense of constriction
in the throat. It was the same sensation that is perceived when one
is for a long time exposed to the heat of the sun without drinking.
In the night a pollution.
19th. After rising, burning in the external canthi and in the urethra :
drawing pain in the inner side of the left fore-arm, during the
whole forenoon, particularly when the arm was at rest. The feeling of
dryness and constriction in the throat appeared again in a slight de-
gree. Drawing in the inner side of the left upper thigh, in the right
knee and in the right hip. At six in the evening, a very unsatisfactory
stool after much straining.
20th. Feeling as if the eyelids were swollen and a foreign body were
in the eye ; drawing, now here, now there, in the extremities ; in the
evening, pressing towards the back in the chest, with oppressed breath-
ing ; no stool.
21st. In the forenoon, an unsatisfactory stool; drawing in the ex-
tremities, especially on the inner surface of the upper part of the left
thigh and forearm (only while at rest.)
2 2d. In the afternoon, another unsatisfactory stool, drawing indiffer-
ent parts of the extremities, not lasting long, but frequently quite trouble-
some.
(59.) Fifth proving with dilution.
1845, January. — After a pause of five weeks, W. on the 27th, 29th,
and 30th, took each day, about six in the evening, two tablespoonfuls
of the 12th dilution of Thuja, and on the 10th of February, at about
five in the evening, he took three ounces of the same dilution. The
dilutions were prepared with distilled water.
30th. He first perceived, soon after taking the drug, feeling of dry-
ness in the throat, lasting two hours ; in the evening, drawing in the
70 Thuja Occidentalis.
right thumb and* forearm ; then in the left thumb and in the teeth of
the right superior maxillary bone. The increased secretion of mucus
obliged him frequently to blow his nose.
31st. In the morning, frequent sneezing, stoppage of the right nos-
tril, alternating with running. This catarrh lasted a couple of hours,
then suddenly vanished ; it appeared again for a little while in the
evening, and ceased suddenly as if cut off.
Feb. 1st. The same symptoms.
10th. Immediately after the dose, feeling of dryness in the throat,
which lasted all day.
11th. Feeling of dryness in the throat the whole evening; pressing
in the left side of the chest, particularly troublesome in the region of
the ribs ; several times, drawing in the lower incisors, and in the first
joint of the right index finger ; violent itching in the lower part of
the sacral region ; at night, sticking from the right velum palati into
the internal ear ; the secretion from the Schneiderian membrane in-
creased.
27th. As a closing experiment, W. drank three ounces of the 30th
dilution (prepared with distilled water) at one draught. This was
at about five in the afternoon ; he perceived no result whatever.
This persevering and energetic experiment is not so rich in results
as the quantity of the remedy swallowed would have led us to expect.
Whether a want of susceptibility to the action of drug must bear the
blame, whether this might have been overcome by still more massive
doses, or whether dilutions taken for a greater length of time would
have given a better result, cannot be determined. We may be per-
mitted to remark, however, that the proving of drugs is no such light
matter as it might appear to be. Both the idiosyncrasy of the prover
and of the drug play so important a part, that a successful proving is
often an entirely accidental windfall for the susceptible prover, while
the boldest experimenter, with the very best will and the greatest de-
votion, if unsusceptible, can only obtain a scanty and one-sided result.*
P.
Dr. Ferdinand Zeiner, forty-two years old, of a delicate constitution
and phlegmatico-sanguineous temperament, healthy from childhood
(except the usual diseases of that period), for the last two years fre-
quently troubled with haemorrhoidal affections, instituted four experi-
ments upon himself with Thuja. (It was his first essay with drugs.)
* The opponents of Homoeopathy have made use of this diversity of result as
an argument against the system. They forget, however, in so doing, that the
susceptibility for drugs (drug-diseases) runs parallel with the susceptibility for na-
tural diseases ; and that, if there be constitutions which a particular disease for
example, variola or syphilis cannot infect, there must also be constitutions which,
cannot be rendered sick by a particular drug. It is only after repeated trials on
individuals of the most diverse constitutions, and under the most varied influences
and conditions, that we can obtain a true notion of the character of a remedy
resting on sure and broad foundations. — Mayrhofer. *'
Dr. Zeiner's Proving' &. (60.) 71
(60.) First proving with the tincture in small doses.
1844, Nov. 1. — Without making any alteration in his ordinary
mode of life, Z. took, in the forenoon, at about nine o'clock (two hours
after breakfast, cafe au lait), one drop of the tincture in water.
Immediately after the dose he experienced vertigo, soon disappear-
ing, scraping in the throat, slight griping above the navel, sticking in
the right temple, numbness of his left foot, and feeling of weakness in
it in walking up and' down the room; feeling of coldness over the
whole body. One hour after, the griping drew from the umbilical re-
gion towards the right groin, and occasioned there flying, often-re-
turning pressing. The vertigo, scraping in the throat, and lame feel-
ing in the left foot still continued.
Two hours after having taken the dose, the vertigo and griping in
the abdomen disappeared in the open air, but single stitches were re-
peatedly felt in the right groin and between the sacrum and anus.
Frequent urination in the course of the day.
At six in the evening, inflation of the abdomen for an hour, which
disappeared by eructations. An hour afterwards (ten hours after
taking the drug) single stitches were perceived in the anus, alternating
with burning in the prepuce.
At about nine in the evening, the prover's smell* was exceedingly,
almost intolerably, increased, so as to become perceptible to those
about him. The night's rest was good; but soon after walking, the
stitches in the anus came on, and the biting in the prepuce also was
troublesome for an hour.
8th. At nine in the forenoon, Z. took another drop in water ; some
minutes after, griping above the navel, and during the first hour ; sin-
gle stitches in the right frontal eminence, scraping in the chest, forcing
him to cough, and quivering in the upper eyelid, pressing in the right
side of the forehead, biting on the upper surface of the glans and in
the prepuce, feeling of weariness in the sole of the left foot when
seated.
At ten in the forenoon, another drop. Soon after, he felt shivering
in the back ; the feeling of weariness in the left foot, the sticking in
the right side of the forehead and the griping in the abdomen con-
tinued. Towards eleven, drawing in the left testicle and frequent
eructations of wind. At two in the afternoon (four hours after the
dose) the itching on the prepuce became almost intolerable. Z. also
observed during the day frequent urgency to urinate, with passage of
a copious urine. Stools regular on both days.
9th. At nine in the forenoon, Z. took four drops on sugar ; soon after,
slight vertigo, griping about the navel, itchings on the prepuce, scraping
in the trachea, obliging him to cough ; with quivering of the right
upper eyelid, burning in the left eye near the internal canthus, com-
pelling him to rub it, weakness of the eyes, single fine stitches in the
*01factus an transpiratio ? — M.
72 Ihuja Occidentalis.
temples, feeling of weakness in the left foot when seated, pressing in
the small of the back. At two in the afternoon, increased secretion of
sweet saliva (lasting five hours), drawing in the left testicle, urgency to
urinate, with copious urine, swelling of the cervical glands, pains in
the small of the back. On the following day, on which nothing was
taken, he felt in the forenoon, the pairs in the small of the back, quiv-
ering in the right eyelid and feeling of weakness in the left foot ; in
the evening, burning in the orifice of the urethra and. frequent stitches
in the anus.
11th. Eight drops of the tincture.' Soon after taking the dose, quiv-
ering again in the right upper eyelid, feeling of coldness with numb-
ness of the left foot, solitary stitches in the shoulders, and frequent
chills over the whole body. At three in the afternoon, a general chill;
drawing in the left testicle, in the left thumb, in the occiput ; sticking
in the temples, in the right side of the forehead and in the left knee ;
pressing in the sacral region.
12th. Z. took nothing. In the evening, sticking now in the left
knee, now in the head, and now in the elbow and finger joints ; then,
general debility, with such weakness in the feet that he thought he
should fall. On the following day, he observed a red spot on the in-
ner surface of the prepuce which itched violently and disappeared after
twenty-four hours.
(61.) Second proving with the third dilution. (5:95).
Nov. 25. After omitting the drug for fourteen days, Z commenced
again, at nine in the forenoon, by taking four drops of the third dilu-
tion on sugar. Soon after, he perceived griping about the navel, itch-
ings on the right knee, on the left shoulder, on the scrotum, and divers
other places, and burning on the inner surface of the prepuce. After
an hour : violent drawing in the testicles ; vertigo ; greatly increased
secretion of saliva (of a metallic taste) lasting two hours, with swelling
of the salivary glands. In the afternocn from four to five o'clock,
sticking pains in the glands of the groin. During the whole day,
slight chills in a warm room ; increased urgency to urinate.
27th. At nine, A. M., eight drops of the third. After a quarter of an
hour, itchings on the prepuce, griping about the navel, sticking in the
left side of the forehead, pressings on the right shoulder ; weakness of
the eyes, particularly observable when writing. After an hour and a
half, renewed increase of saliva (of an acid taste) during two hours ;
sticking in the anus and violent stitches in the left side of the chest
which frequently returned throughout the day ; continual slight chills
and increased secretion of urine.
28th. The symptoms of the preceding day were repeated after taking
twelve drops of the same dilution.
(62.) Third proving with the tincture in strong doses.
Dec. 17. Z. ceased taking the drug for eighteen days, and com-
Dr. Zeiner's Provings. (62.) 73
menced again by taking fifteen drops of the undiluted tincture, -where-
upon, in the course of the day, he observed the following symptoms :
pressing in the forehead, frequent stitches in the frontal eminences,
sticking, at one time in the right, at another in the left side of the chest,
griping about the navel ; scraping in the throat, intolerable biting in
the anus, drawing in the left testicle, obscuration of the eyes while
writing.
18th. Twenty drops of the tincture. Soon after the exhibition of
the dose: staggering while walking in the air; pressing in the middle
of the forehead, sticking in both frontal eminences (lasting the whole
day, and continually increasing) ; general debility and weakness in the
feet : sticking in the shoulders and in the right knee ; stitches in the
region of the groins, often repeated during the day, with the feeling as
if the inguinal glands were swollen ; intolerable itching in the anus,
lasting almost the entire day ; hasty urgency to urinate, with copious
urine.
19th. No medicine. On awaking, sticking pain in the left frontal
eminence, as well as violent pressing between the shoulders, which feel-
ing had entirely disappeared eight days before ; frequent twitching in
the middle finger of the right hand. The itching in the anus appeared
but seldom.
20th. After twenty-five drops ; dull confusion in the head, weak-
ness in the feet when walking; stitching in the forehead and in differ-
ent parts of the body, especially in the shoulders, arms, and legs ; in the
evening, spitting of much saliva. The itching in the anus is almost
gone ; the tongue and palate are very sore.
On the following three days, no dose.
21st. On awaking, sticking in the left shoulder, and in the course
of the day flying stitches in the glans ; there was also an increased
secretion of saliva.
22d and 23d. The whole of the symptoms gradually disappeared,
and the prover no longer perceived the troublesome itching in the
anus which had so much annoyed him during the whole continuance
of the experiment.*
24th. Z. took thirty drops. During the first two succeeding hours :
burning and itching in the anus, griping about the navel, painful
constriction in the hypogastrium, weakness in the feet, cracking in the
knee-joints, drawing in the right groin and pressing in the renal re-
gion. At six in the evening : pressing in the forehead, sticking in
the left frontal eminence, acid taste with increased secretion of saliva,
swelling of one (which ? — M.) of the cervical glands (tonsils ? — M.)
(63.) Fourth proving with the 12th dilution. (10 : 90)
1844, January 4th. After having rested ten days, Z. took ten drops
* In my case this itching in the anus was the most durable symptom, and disap-
peared after the lapse of several weeks. — Mayrhofer.
F
74 Tlmja Ocddentalis.
of the 12th dilution. During the first two hours, he observed during
rest : transient griping about the navel, repeated stitches about the
anus, which continued to increase in violence during the day, eructa-
tions of wind, sticking in the left side of the chest, on the left scapula
and right temple, failure of the eyes when reading, transitory chill
over the whole body with cold hands in a heated room, pressing, at one
time in the right, at another in the left arm, drawing in the fingers,
pain (of what sort ? — M.) in the nape of the neck, stitches in the left
side of the forehead, numbness of the sole of the left foot while sitting,
crawling in the toes, extraordinary weakness in the left foot when
going out, slight reeling, pains in the small of the back, and increased
secretion of saliva.
At four in the afternoon, drawing in the left testicle with feeling of
weight in it, urgency to urinate with copious passing of water.
During the three following days, no medicine being taken, frequent
pressing in the forehead, sticking pains in the frontal eminences and
temples, pressing between the shoulders.
8th. Fifteen drops of the 12th. During the first two hours: press-
ing and sticking in the forehead, sticking in the shoulders, stitches in
the anus, numbness of the left foot, drawing in the left testicle, feel-
ing in the testicles as if they moved, drawing in the fingers and press-
ing in the left upper arm.
All these symptoms disappeared while walking in the open air.
9th. No dose. Frequent itching on the glans and prepuce, alternat-
ing with stitches in tlie anus, and the urgency to urinate was frequent
and hasty.
1 2th. The proving was concluded by taking twenty-five drops of the
12th dilution. Thereupon he observed : pressing in the middle of the
forehead, sticking pain in the right axilla, increased salivary secre-
tion, which lasted all day, stitches in the inguinal glands, itching in
the anus, flying stitches in the glans, weakness of the eyes when
reading, pressing between the shoulders and crawling in the toes of
the left foot, which were painful in treading. In the afternoon, while
seated, feeling of lameness in the left foot. At seven in the evening,
when walking, uncommonly violent stitch between the coccyx and the
anus.
13th. After waking, sticking in the left side of the chest, lasting all
day.
On discontinuing the drug, all the abnormal manifestations dis-
appeared.
Dr. Zeiner accompanies his beautiful and instructive proving with
the remark, that during its whole period, the sexual desire was com-
pletely asleep ; and he further made the observation, in accordance with
the experience of other provers, that the greater part of the drue-
flymptoms were most clearly developed during rest.
Dr. Von ZlatarovicK s Provings. (64.) 75
Q.
The boldest and most indefatigable prover of Thuja was Prof, vou
Zlatarovich, who took in 155 days, 42,260 drops of the tincture in
large doses. He proved it not only on himself, but also upon a female.
1.
Zlatarovich's proving upon himself.
[ (64.) First proving with increasing doses of the tincture.
1844, Sept. 6th. Z. began his proving with six drops of the tincture,
which, as also the succeeding doses, he took in the morning, fasting.
On the three following days, he took eight, ten and twelve drops, and
experienced no effect. On the 10th, after taking fourteen drops, he
first perceived, in the evening, a transient pain in the vertex, as though
the bone were repeatedly pierced with a needle near the sagittal
suture.
11th. No effect after sixteen drops.
12th. After eighteen drops, in the evening, pressing and burning in
the hemorrhoidal vessels (? Ed.) and frequent violent sneezing, which
returned on the morning of the 13th, after twenty drops.
From the 14th Sept. to the 5th of October inclusive, Z. increased the
dose daily by two drops, and observed the following results :
Sept. 14th. After dinner, frequent violent sneezing without catarrh,
(a thing very unusual with him).
15th. In the morning, several times, short, dry, barking cough.
16th. In the afternoon and evening, pressing in a small spot under
the sternum, which gradually extended to the scrobiculus.
17th. At night, and on waking, several times, short, interrupted,
convulsive cough, which is excited by an inclination in the larynx, and
leaves an unpleasant dryness in it. At noon, moderate appetite, head
somewhat confused, especially in the forehead, the throat dry and
rough, and some difficulty in swallowing. In the evening he felt very
weak and unwell, with heaviness and tension in the feet, so that walk-
ing was painful ; the head ached in that part of the anterior half
which was covered with hair, as though compressed : nevertheless, a
very good night succeeded.
18th. Of the catarrhal symptoms, nothing is left except a little rough-
ness in the throat. This also disappeared by noon, and he felt well
again. Until this point in the experiment, the sexual impulse had been
much exalted.
19th. A good night's rest was followed by a day destitute of
symptoms.
20th. On rising, inconsiderable cough and roughness in the throat,
disappearing by noon. In its place appeared troublesome dryness and
sensitiveness of the nose, as at the commencement of a catarrh. This
76 Thuja Occidentalis.
sensation extended by degrees into the frontal sinuses, and the eyes
also became sensitive. These catarrhal symptoms disappeared again
during the afternoon. At the commencement of dinner, a jerking con-
strictive pain was felt in the hairy portion of the head, and in the
afternoon painful tension in the right popliteal space.
21st. In the forenoon, dull confusion of the head; slight burning in
the stomach, and in the left external canthus. At two o'clock, violent
burning in the eyes and eyelids ; frequent sneezing. The roots of the
hair of the left eyebrow are sensitive when passing the hand over them.
At dinner, burning tearing in the whole left side of the face, apparently
in the periosteum. After dinner, general uneasiness for a couple of
hours. In the evening burning pressing pains in the left eye, on the
whole upper surface of the globe, aggravated by the touch ; sensitive-
ness of the left temple ; slight drawing in the nape, and repeated
sticking from the nape to the right ear and axilla, After supper, dull
confusion in the head for an hour. On lying down, the right leg was
so painful, that he was obliged to place himself on his left side, contrary
to his usual habit, and so to lie during the whole night.
For several days the skin on the vertex has been sensitive to the touch,
and shines so clearly through the hair, that the prover was afraid he
was becoming bald.
22d. On awaking, some headache in the forehead; after rising, the
same feeling in the left nostril and right frontal sinus came on that had
been experienced two days before ; but now the right nostril was en-
tirely free from it. At noon, frequent blowing of thick mucus from the
nose. The whole right leg was painful. Repeated urgency to urinate,
even when there was but little water in the bladder. In the evening,
all the morbid symptoms had vanished, except that a little spot upon
the vertex still remained sensitive to the touch.
23d. No symptoms ; two liquid stools which were evacuated soon
after taking the dose, seem to have prevented their appearance.
24th. He had no other symptoms to-day, than a slight burning in
the hemorrhoidal vessels, and copious secretion of mucus from the
nose.
25th. In the morning, dull confusion in the head, especially in the
region of the forehead and temples, which an hour after began to in-
crease and extended over the vertex, but subsequently entirely disap-
peared ; slight burning in the canthi. After dinner, general weari-
ness with slight headache in the forehead. In the evening tension in
the extensor muscles of the extremities and trunk, now here now there •
subsequently heat.
26th. Normal feelings during the day. In the evening, drawing and
sensation of iveariness, with apparent dullness of feeling in the limbs
especially in the upper and in the forearm near the wrist; dull confu-
sion in the head, especially in the forehead. Intellectual exertion soon
fatigues ; tobacco smoke is not as agreeable as at other times ; frequent
yawning.
Dr. Von ZlatarovicWs Provings. (64.) 77
27th. In the afternoon, slight dulness in the head; no other
symptom.
28th. In the night, frequent cough with raising of thick mucus.
After dinner, general uneasiness, restlessness, swelling of the abdomen,
feeling as if beaten in the upper arms. In the evening, good health.
The cough ceased in the day.
29th. On awaking, the glans is very sensitive ; drawing back the
prepuce causes pain ; frequent dry hacking cough. Soon after the dose,
general uneasiness and stretching of the limbs. In the evening, frequent
violent sneezing and tickling in the nose.
30th. In the morning frequent sneezing again, with increased secre-
tion of mucus accompanied with frequent dry hacking cough.
Oct". 1st. During the day, frequent dry hacking cough : in the fore-
noon, when walking, some itching in the hemorrhoidal vessels : after
dinner, strong inflation of the abdomen.
2d. In the forenoon, violent itching and pressing in the hemorrhoi-
dal vein.
3d. In the forenoon, on the upper lip, an elevated, red, violently
itching spot, which compelled him to scratch, but was gone without a
trace at the expiration of an hour.
4th. In the morning, frequent violent sneezing, in a short time ends
with dulness of the head : after dinner, extraordinary distention of the
abdomen, which seriously embarrassed the respiration.
5th. No symptoms after taking sixty-four drops.
6th. Seventy drops. At night, much flatulence was discharged. In
the morning sneezing ; burning in the skin of the right lower leg.
After breakfast, frequent eructations with the taste of Thuja ; frequent
short, dry, interrupted cough ; slight chill. In the evening, sudden,
cramp-like twitching of the under lip, and here and there in circum-
scribed spots on the skin.
From the 7th to the last of October, he increased the dose daily by
five drops, so that on the first day he took 75, and on the last 195
drops. The following were the results :
7th. No symptoms.
8th. An hour after the dose, squeezing in the haemorrhoids .
9th. No symptoms.
10th. Discharge of bloody slime from the anus, as well by day as
at night ; frequent discharges of flatulence, which were always accom-
panied by some moisture. Towards evening, uncommonly strong ap-
petite, which must be appeased ; subsequently, pressing in the hemor-
rhoidal vein when seated.
11th. No symptom worthy of mention appeared during the whole
day, but in the evening, after much conversation in company, a press-
ing headache began in the forehead, extended gradually towards the
vertex, and slowly disappeared.
12th. One hundred drops. Slight drawing behind the right ear,
and some constriction in the ear ; ache in the forehead, which, after
78 TJiuja Occidentalis.
an hour, merged in the sensation as if a wedge were driven into the
temple. Sneezing did not aggravate the headache, but motion of the
head and swallowing had that effect. At the same time, cheerful dis-
position and inclination to intellectual exertion. In the night very-
good sleep.
13th. Uncommonly comfortable and easy.
14th. In the morning, transitory burning in the anus. At noon,
tension in the whole right leg, while walking. After dinner, slight
sensitiveness in the skin under the hair on the forehead, where the cool
air at the open window was exclusively felt.
15th. At noon, frequent violent sneezing.
16th and 17th. No symptoms.
18th. In the afternoon, burning and pressing in the stomach, lasting
several hours.
19th. Several small, painless tubercles appeared upon the head. The
hair comes off on the vertex.
20th. In the morning, raising of tough mucus ; in the forenoon,
itching in the perinwum, when seated ; slight drawing over the left
eyebrow.
21st. At noon, great dulness of the head; drawing in both thighs.
In the evening, pressing in the forehead and in the right temple.
22d. On waking, ache in the forehead, which disappeared again after
half an hour. After a normal evacuation, burning and drawing in of
the anus. At noon, drawing in the lumbar muscles, while walking.
23d. At noon, drawing again in the loins. The lumbar vertebrae
are somewhat painful when leaning forward in sitting ; feeling of sore-
ness in the perina-um.
24th. No symptom during the whole day.
25th. In the morning, on rising, drawing from the loins towards the
nates. After dinner, very violent itching in the anus.
26th. At night, increased secretion of mucus in the larynx and
trachea.
_ 27th. Slight pressure in the hemorrhoidal vein ; in the evening,
slight drawing in the left upper arm.
28th. Drawing, now here, now there : but worse on the left side of
the body : burning in the external canthi.
29th. In the morning, slight heat and redness, with burning on the
upper lip ; drawing in the left arm.
30th. On awaking, frequent violent sneezing with tickling in the
nose, and burning in the eyes, as though a catarrh were coming on ;
drawing in the right forearm.
31st. In the forenoon, itching and burning in the hcemorrhoidal
vessels, when walking ; internal shuddering and feeling of cold the
whole afternoon, with dull confusion in the head. In the sulcus inter
nates, a clammy moisture is secreted.
Nov. 1st. The dose was omitted ; drawing in the limbs, particularly
in the right forearm, aggravated by movement of the limb ; coldness
Dr. Von Zlatarovich's Provings. (64.) 79
in the hands and feet ; drawing in the whole right leg ; pressing in
the left side of the chest. %
2d. Two hundred drops. In the morning, roughness in the throat
with continual inclination to hawk, and with a deeper tone of the voice,
which disappeared again after breakfast. At noon, burning and feeling
of soreness in the anus.
3d. Two hundred and five drops. In the forenoon, drawing in the
right elbow joint, and squeezing in the hemorrhoidal vessels.
4th. No dose. At noon, violent itching and squeezing in the haemor-
rhoids : tension in the extensors of the right arm, when writing. In the
afternoon, normal state. In the evening, a renewal of the violent
squeezing and pressing in the anus ; very earnest frame of mind, in
spite of the cheerfulness of those around him ; a small suppurating
boil on the back.
5th. Two hundred and ten drops. At noon, drawing in the right
lower leg, especially on the outside towards the ankle, and in the right
hand, particularly in the thumb. In the afternoon, from four to six
o'clock, severe burning and pressing in the stomach.
6th. Two hundred and twenty drops. In the forenoon, burning in
the stomach for an hour. At noon, flying stitches on the right side
near the sternum for a quarter of an hour.
These stitches had this peculiarity, that instead of being aggravated,
they disappeared on taking a deep inspiration, and returned again only
on the succeeding expiration. In addition, slight tension in the exten-
sors of the right hand, and drawing in the dorsum of the right ring
finger.
7th. Two hundred and twenty-five drops ; and he daily increased the
dose by five drops until — and including the 16th of November, when
he took two hundred and seventy drops — in the morning, discharge of
copious, inodorous flatulence, and a hard unsatisfactory stool ; tension
in the bend of the right elbow, when writing.
8 th. In the forenoon, pressing and burning in the stomach for an
hour. At noon, he perceived a sensation as if the lower part of the
thorax were surrounded with a bandage, which sensation disappeared
in the afternoon. In the evening, a very disagreeable pressing in the
region of the heart, confined to a small spot.
9th. Immediately after the dose, rolling and rumbling in the intes-
tines ; afterwards, frequent dry hacking cough ; tension in the right
hand, especially in the thumb ; the same in the outside of the right
thigh, extending into the knee, particularly when walking and bending.
In the forenoon, the right knee-joint was painful when seated, but the
pain soon disappeared, and was succeeded by a feeling of cold in the
knee. A transitory pressing and tension in the heart then came on,
and on its ceasing, the coldness in the knee was again perceived, but in
a less degree. All these symptoms were gone at noon. At half-past
one, on closing the eyes, a feeling of vertigo, (an obscure designation !
M.) The power of thought was increased, but rather for analytical
than synthetical reasoning.
80 IJivja Occidentalis.
10th. Half an hour after the close, rumbling in the intestines, with
slight griping; frequent coughing up of mucus.
11th. In the morning, roughness in the throat, and frequent hack-
ing cough. The upper lip somewhat swollen, and burns. After a
loose stool, burning in the anus. After dinner, dull confusion of the
head ; afterwards, heart-burn. These symptoms disappeared in the
open air. In the evening, slight burning in the eyes.
12th. In the morning he felt well. At noon, dull confusion of the
head; burning and dryness in the right nostril, up as high as the
frontal sinuses ; slight burning in the right eye ; oppression in the
lower part of the thorax ; frequent short, dry hacking cough. He feels
much better in the open air than in the room ; the indefinite feeling of
uneasiness, however, cannot be exactly described. In the evening,
the knees were painful while walking, as though bruised ; the weight
of the body seems to him to be too great for the legs.
13th. At night he urinated more than usual. In the morning,
after rising, frequent raising of mucus, leaving behind a feeling of sensi-
tiveness in the larynx : discharge of copious inodorous flatulence.
After dinner, drawing behind the right ear, with single stitches in the
mastoid process of the temporal bone. When this symptom had dis-
appeared, as it soon did, short accesses of crawling and running on the
left side of the occipital bone came on ; also, burning and pressing in
both eyes.
14th. On waking, aching in the forehead, which disappeared by de-
grees after rising, but returned at about half-past nine, became heavy and
pressing, and only vanished after four hours ; after which, pressure on
the vertex, as if a weight lay there. To these were added, weariness
and uneasiness in the whole body, coolness and flying shudderings over
the back. At noon, his food had a disagreeable bitter-sharp after-
taste, which was recognised, especially at the root of the tongue and in
the fauces. The uneasiness became* less after dinner, but even black
coffee left behind an unpleasant after-taste.
15th. Soon after the dose, constriction about the navel and slight
pressing in the lower border of the light orbit, soon going off; but
the orbital edge remained sensitive to the touch, and to the closing of
the eye for a quarter of an hour. Afterwards, tension in the right
ankle while walking. The respiration is not altogether free; the
thorax is raised during inspiration, with somewhat more difficulty' than
usual, and a short, dry hacking cough frequently comes on : a violently
itching tubercle makes its appearance upon the upper lip, near the
right corner of the mouth.
16th. An hour after the dose, oppression of the chest; troublesome
breathing, drawing between the shoulders, burning and pressing in the
stomach, increased by movement and by speaking. Constriction of the
anus after two papescent stools. Also, heaviness and lameness in the
right arm, and slight drawing in the right masseter, with confluence of
saliva into the mouth.
Prof. Von ZlatarovicKs Provings. (G5.) 81
From the 17th to, and including the 29th, he ceased to take the
Thuja, and observed the following symptoms :
17th. In the night, drawing in the right upper arm, axilla, and
shoulder, preventing his lying on that side. In the morning, these
pains became intolerable, but by warmly wrapping up the painful
parts, they gradually diminished, and finally entirely disappeared, leav-
ing behind a feeling of lameness in the arm. At about half-past nine,
the tearing in the shoulders and upper arm returned in frequent short
attacks. After dinner, general weariness and universal feeling of dis-
comfort. In the evening he feels generally better, but the pain in the
shoulder is again very violent, and in the right arm ; especially in the
forearm there is a condition bordering upon paralysis, with feeling of
coldness. Before going to sleep, very gloomy frame of mind.
18th. At ten in the forenoon the pain in the arm came on in short
accesses, was sensible until noon, but was milder than the day before,
and ceased entirely in the afternoon. The mind became more cheerful
again.
19th. The pain in the arm is entirely gone, and Z. feels well the
whole day.
20th. At noon, slight drawing in the small of the back, drawing in
the left groin and frequently a dry hacking cough. No trace of the
pain in the arm. '
21st. Burning in the whole nose, which seems to feel as if swollen,
with increased sensitiveness on the septum, on which several vesicles
are to be seen. The upper lip is likewise sensitive. In the afternoon
these symptoms have disappeared again, and the vesicles on the nose
are dried up. On the two following days no drug symptoms were
observed.
24th. In the evening of the 24th and the whole forenoon of the
25th an exceedingly troublesome headache came on, which was seated in
the upper surface of the vertex, was heavy and pressing, and from time
to time in single stitches and thrusts. The brain was apparently unaf-
fected, but the head externally was somewhat sensitive to the touch, as
were also the eyes. Cool air diminished the pain ; when it was at the
worst, he supported his face in the concavity of his hand, and for some
time rubbed his forehead, eyes and face, whereupon the pain entirely
disappeared, and in the evening his head was wholly free, except a
slight crawling and running on the places before indicated. On the
four following days, no symptoms.
(65.) Second proving with massive doses of the tincture.
Nov. 30th. 300 drops of the tincture. Two hours after, slight tear-
ing in the nape, and distension of the abdomen by flatulence.
Dec. 1st. No medicine was taken. In the morning he remarked
upon the forehead over the root of the nose, a red streak, which did
not itch nor present any appearance of roughness, and was visible until
G
S2 Thuja Occidentals.
noon. He had a feeling over the crest of the light ilium, on touching
it, as if it hfid been bruised. At noon, a transient drawing came on in
the first joint of the right thumb which was, in consequence, somewhat
less easily moved.
2d. 300 drops. In the forenoon, the red streak was again visible
upon the forehead, but no other especial symptom manifested itself the
whole day.
3d and 4th. 300 and 310 drops produced no effect.
5th. 320 drops. There appeared in the sulcus between the nates,
not far from the anus, a painful spot, which felt sore for an hour.
6th. No drug and no symptoms.
7th. 330 drops. Immediately after the dose, flying stitches in dif-
ferent parts of the body ; frequent dry hacking cough ; afterwards,
raising of mucus ; in the afternoon, pressing and burning in the stomach
for an hour ; then, transient feeling of pressure in the heart and single
stitches in the lower half of the right side of the chest. Not the
slightest trace is perceptible of the hemorrhoidal congestion, which
was usual during the earlier days of the experiment, and this the
prover considers as a curative effect of the drug.
8th. No dose and no symptoms.
9th. 340 drops. In the afternoon, slight burning and pressing in
the stomach during an hour. In the evening general weariness and
uneasiness, with dull confusion of the head ; drawing in the joints of
the hands and feet. The abdomen w T as incommoded by a supper
which was eaten with hearty appetite.
10th and 11th. 350 and 370 drops produced no symptoms.
12th. 380 drops. In the morning, a small, painless, non-itching
tubercle near the raphe of the perinaium ; the eyes on waking were
glued with mucus. In the afternoon, relaxation and sleepiness. In
the evening, inclination for exertion ; frequent slight drawing from the
mastoid process of the right temporal bone downwards. Afterwards
single, flying, very painful stitches from the depth of the right ear
through the external ear. An hour after, when the ear-ache had dis-
appeared, a violent stitch drove suddenly through the left temple as if
an awl had been forcibly thrust into the brain. The pain lasted but a
few seconds, but the spot remained for some time sensitive.
13th. 400 drops. In the morning, feeling of fulness with stoppage
in the right ear and frequent sneezing, which returned in the evening,
soon after which pretty violent i idling in both nostrils towards the point
of the nose, after a short continuance of which, a secretion of a thin
mucus followed. Also, sticking drawing on the inner surface of the
left forearm towards the wrist, nausea mounting from the abdomen,
with slight inclination to vomit.
Z. made the observation that the morbid feelings produced by Thuja
are aggravated during rest; and by remaining quiet, symptoms are
developed which disappear on motion in the open air.
14th. No dose and no further symptoms except tension in the flexor
surface of the ri<?ht leg and inflation of the abdomen.
Prof. Von ZlatarovicKs Provings. (65.) 83
15th. 410 drops. In the afternoon a couple of transient tearings in
the tendinous expansion on the right side of the neck.
16th. 420 drops. During the whole forenoon a very unpleasant
sensation of cold, the external temperature being + ]R. (34° F.).
The hands and feet are icy cold and the skin of the hands is purple.
At noon, before dinner, for a little while oppression of the chest ivith
difficult respiration and slight pain in the anterior surface of the sto-
mach on taking a deep inspiration, as though from external pressure.
In the afternoon and evening, these symptoms were gone.
17th. No drug and no symptoms.
18th. 430 drops. Soon after the dose, tenesmus and a hard, very
unsatisfactory stool ; also, transitory pressure on the chest ; burning in
the urethra towards the bulbus for several minutes ; in the evening,
something of a headache ; at night, quiet sleep.
19th. No dose. On awaking, violent pressing headache in the ver-
tex, which went off by degrees while he was still in bed, and disap-
peared entirely after he had arisen. Breakfast did not relish ; and
while at table, slight vomiturition ; to which were added general wea-
riness and faintness, with pressure and sensitiveness in the eyes.
20th. 450 drops. Not a trace of a symptom appeared in the fore-
noon ; even the eructations with the taste of Thuja, which formerly
were sure to come soon after taking the drug, did not once manifest
themselves. In the afternoon, general malaise, with a sensation as if a
chill were about to come on. Dull confusion of the head for half an
hour.
21st. No dose. In the morning, burning in the skin of the right
lower leg ; slight sensitiveness in the vertex and right eye ; feeling of
soreness at the anus. Towards noon, throbbings in the right temple,
when rising from a seat. Dinner was devoured with a veritable canine
appetite. Two hours afterwards, general malaise, frequent dry hack-
ing cough, and slight dulness of the head. In the evening, pressure in
the haemorrhoidal vessels when sitting. A painful inflamed tubercle
makes its appearance on the right side of the forehead, and the neck
appears as if swelled, so that the loose neckcloth is troublesome. Se-
renity of mind.
2 2d. No dose and no symptoms.
23d. 500 drops. In the morning, before the dose, short, dry, trou-
blesome cough, without the former catarrhal symptoms. After it had
gradually become quieted, by taking sugar moistened with water,
violent burning in the stomach came on, which lasted until he got up.
In the forenoon, uneasiness^ and sensitiveness to the cold air; at noon,
troublesome drawing in the right radius, along the forearm as well as
in the hand, into the little finger. In the afternoon, heart-bum.
24th. In the afternoon, when passing his water, slight burning in
the urethra.
25th. In the morning, on walking, he had a violent erection, with
strong desire for coition ; but notwithstanding the existing voluptuous
feeling, there was no emission, which is not usually the case with him.
84 Thuja Occidentalis.
He felt besides, weight and tension in the right leg, and in the evening,
burning in the eyes, especially in the internal canthi.
26th. He felt perfectly well, and so on the 27th he again took five
hundred drops. On awaking (before the dose), the sexual impulse
was again active, and on this occasion, with normal results. After the
dose, in the forenoon, violent tension in the right lower leg, on which
the skin was painful as though sore and ulcerated, which sensation was
lessened after dinner. In the afternoon again, a very violent erection.
Afterwards, a delightful feeling of corporeal well-being and inclination
to intellectual labor. In the evening, his foot was entirely without
pain, and a short, dry, interrupted cough was excited by tobacco
smoke.
28th. 500 drops again. In the forenoon, when walking in the open
air, slight transient colic. As he came in at night from the cold air
into a room, he felt a very violent stitch in the right ear, from the ex-
ternal part inwards to the internal, which compelled him to hold his
breath, and left the ear sensitive for a while.
29th. No dose. In the morning another but less severe attack of
the pain in the ear came on. He had a sensation in the ear, as if the
free access of the air were prevented, but without the slightest diminu-
tion of the hearing. In the forenoon, the ear was well again ; but
after dinner he had the feeling in it as if the external organ were filled
with water, similar to the sensation felt when one dips his head under
the surface. Drawing and tension in the occiput. The right lower leg
was twice painful during the day.
30th. 500 drops. Immediately after rising, the pain in the right
lower leg again established itself. A spot next to the tibia, near a
varicose dilatation, smarted as though it was sore, was very sensitive to
the touch, and the skin over it was slightly reddened. In the forenoon,
burning and pressing in the stomach. At noon, but little appetite.
In the afternoon, strong inflation of the abdomen ; burning in the sto-
mach ; dry, short, hacking cough, and peevish humor. In the even-
ing, the right lower leg was again painful upon its upper surface, as
if sore.
31st. No dose. On rising, after a very good night's rest, the pain
in the leg again made its appearance. The spot which we noticed yes-
terday is still sensitive, but no more reddened. The ear, which for
some days has not felt altogether right, is now entirely recovered. In
the afternoon, heart-burn. In the evening he felt well.
1845, Jan. 1st. After a good night's sleep, he awoke with a very
severe pressing headache, which, at the commencement, was confined
to the vertex : after a while extended to* the frontal eminences and
eyes, and again returned to the vertex and disappeared. In the morn-
ing, he hawked up a thick tenacious mucus from the larynx. Althouo-h
no Thuja had been taken, still the burning in the right lower leg deve-
loped itself in the forenoon, as did also, for a little while, a reminiscence
of the earache of the 29th December. In the afternoon, severe burning
on the inner side of the right lower leg was again troublesome. In the
Prof. Von ZlatarovicTi's Provings. (65.) 85
evening, the head and ear were entirely relieved. But when he espe-
cially directs his attention that way, the head and earache threaten to
come on again, which is not the case when he intentionally fixes his
mind upon the other suffering parts.
2d. 500 drops. In the forenoon, frequent eructations of wind pre-
ceded each time by painful constriction of the stomach. Instead of the
right, the left ear has, to-day, a touch of the sticking pain. The right
lower leg is still sensitive in the spot upon the tibia, heretofore indi-
cated.
3d. 500 drops. Heaviness of the right leg, with burning on the
whole inner surface of the lower leg. At two, in the afternoon, slight
searching and griping about the navel. In the evening, great drow-
siness.
4th. No dose. In the morning, after much straining, a very hard
evacuation, followed by pain in the anus. At the same time, borbo-
rygmus, and three hours after, a couple of liquid stools, with subsequent
burning in the anus (over an hour). Pressing and burning in the sto-
mach, two hours after dinner. The right foot is less painful than yes-
terday. Several inflamed tubercles are visible on the face.
5th. 500 drops. In the morning, frequent hawking up of thick
mucus. The burning in the right lower leg is drawing nearer to the
ankle. After breakfast, a very unpleasant sweetish salt taste, especially
in the back part of the mouth and on the root of the tongue. At ten,
in the forenoon, pressing and burning in the stomach for a quarter of
an hour ; afterwards repeated coughing up of mucus. In the evening,
heaviness and burning again in the right lower leg. The hinges of the
under jaw crack when he yawns ; a wholly unusual occurrence.* In
the night, the whole right leg up to the hip-joint was painful, heavy,
and less movable. The pain was drawing and tensive.
6th. 500 drops, after which the dose was omitted for six days. The
following were the results : Soon after the drops, burning in the throat,
obliging him to hawk ; then slight raising of thick mucus ; frequent
sneezing, with obstructed nose and roughness in the throat. These ca-
tarrhal symptoms became more severe in the evening, and were accom-
panied by aching in the forehead, with weight and pressure in the
eyes, and were followed by a very restless night.
7th. According to the report of his wife, he has slept very uneasily,
has constantly rolled about in bed and moaned. On waking, his throat
is entirely coated with phlegm, and after hawking, the larynx and
trachea are painful. Then, general malaise both of body and mind ;
his head aches in the forehead, his eyes burn, his nose is obstructed,
and his voice is hoarse. At noon, he felt better when walking in the
open air, but when at rest the aggravation again returned. There was
much flowing from the nose, his feet were cold, and the general feeling
of illness sent him to bed early in the evening. It was, however, a
long time before he could get warm, and dulness of the head, frequent
* Compare Dr. Ruber's proving.
£& Thicja Occidentalis.
cough, stoppage of the nose, and, in short, all the symptoms of a slight
catarrhal fever set in.
8th. This morning he felt very uneasy, and very weak, and lay in
bed until ten o'clock. Afterwards he felt better. At noon, buzzing in
the head, which feels dull, frequent dry cough, pressure in the hemor-
rhoidal vessels; for the rest, good appetite. After dinner, burning in
the stomach lasting until evening, when a short, jerking, dry cough took
its place. Nevertheless he was incomparably better in the evening
than on the previous day. The febrile symptoms came on again at
night, but ceased after midnight, whereupon quiet sleep succeeded, and
towards morning perspiration broke out.
9th. During the night burning in the stomach. On awaking, fre-
quent dry hacking cough, and somewhat deeper and hoarser voice. At
noon, buzzing and roaring in the head, and feeling in the extremities as
though they had been bruised. In the evening, troublesome dryness
in the nose up into the frontal sinuses.
10th. In the night, grumbling and rumbling in the intestines. In
the morning, frequent coughing up of thick mucus. On rising, burn-
ing in the eyes* At noon, a great improvement over the preceding
day ; in the afternoon, at one o'clock, while sitting, single flying, very
painful stitches in the anus, as if from a fine needle. These stitches
returned from time to time, but not in so frequent a succession as at the
beginning. Troublesome dryness in the nose. After dinner, great in-
flation of the abdomen, to which was added roaring in the head. On
movement in the open air, these symptoms disappeared.
11th. On awaking, frequent coughing up and blowing from the nose
of thick mucus; subsequently, a return of the troublesome dryness of
the nose with sensitiveness of the eyes. At eleven in the forenoon, vio-
, ressure in the hemorrhoidal vessels. In the evening, the earlier
catarrhal symptoms returned, accompanied by sensitiveness of the eyes
and frequent dry cough.
12th. No symptoms to-day, except a frequent dry cough.
13th. 500 drops. In the forenoon, squeezing and pressing at the
anus ; in the afternoon, he felt well. No cough came on, notwithstand-
ing he smoked and spoke much. After supper, flying tearing in sepa-
rate jerks from the angle of the under jaw to the os hyoides pretty deep
in the integuments.
14th. 500 drops. Again troublesome dryness in the nose with tick-
ling ; then griping in the intestines, burning in the right lower leg, and
after a very well relished breakfast, a bitter sharp-salt taste in the mouth,
particularly about the root of the tongue. In the forenoon, the dryness
and pressure in the nose and frontal sinuses so increased, that he was
very much incommoded by it in his lecture. At noon, a catarrhal
flowing came on, and disappeared again entirely in an hour after.
Soon after the pressure on the root of the nose, and copious secretion of
mucus returned. The pressure on the root of the nose afterwards drew
off towards the ears, where it produced tension in the auditory pas-
sages and stoppages of the ears. This symptom vanished again, after
Prof. Von Zlatarovictts Proving s. (65.) 87
some time, and in place of it transitory pressure in the hemorrhoidal
vessels was perceived. After supper, pressing and burning with occa-
sional painful constriction of the stomach.
15th. 500 drops. Immediately after the dose, dryness and tension
in the nose, with the feeling as if the whole mucous membrane were
sivollen; the taste in the mouth alluded to yesterday also appeared.
These symptoms disappeared after an hour. At two in the afternoon,
emission of sparing and exceedingly dark colored urine, causing burning
in the urethra.
16th. A mucous cough set in in the morning; no dose was taken,
and with this exception no symptoms were perceived.
17th. 500 drops. In the morning, frequent coughing up of thick
mucus. At noon, while sitting quietly in the room, the familiar trou-
blesome, dry feeling in the nose appeared, which was much ameliorated
in the open air, but returned, though less violently, on coming into the
house again. The nose first became moist after he had smoked a cigar.
He noticed, in addition, two painless tubercles about the size of a hemp-
seed in the sulcus "between the nates not far from the anus. In the even-
ing he perceived some painful spots on the head, at most the size of a
penny. The pain seemed to be seated in the bone itself.
18th. 550 drops. On awaking, he felt his head all over, but could
not detect yesterday's sensitive spots : the tubercles near the anus were
also missing. In the forenoon, frequent cough, w r ith raising of thick
mucus; in the afternoon and evening, short dry cough.
10th. 575 drops. Discharge of much loud inodorous flatulence,
and frequent raising of thick mucus with slight cough.
20th. 600 drops. In the morning, frequent violent sneezing, with
cough and raising of mucus, and slight burning of the eyes. He re-
marked, on accidentally touching the raphe of the pcrinaium, that on
the right side it was sharply prominent, and felt thickened as if the
skin were indurated, without being in the least painful. Violent heart-
burn an hour after dinner, lasting a couple of minutes, then lulling for
several minutes, then returning, and so coming on in frequent accesses.
Through the whole day, the nasal secretion was tolerably copious, and
thick mucus was thrown off by frequent coughing. Pressure in the
stomach was occasioned by roast meat eaten in the evening. He also
perceived, here and there, a slight drawing under the skin in the tendi-
nous expansions, and on making certain movements with his head
a creaking in the cervical vertebra?. This symptom had already
been frequently observed by the prover without any particular atten-
tion being paid to it, but to-day it was troublesome in a much greater
degree.
21st. Nodose. He slept remarkably well during the night. In the
morning he coughed up mucus once or twice. Towards noon, a very
unpleasant, pressing headache came on in the vertex, which diminished
in the afternoon, and disappeared in the evening. At six in the even-
ing, slight burning in the stomach and frequent coughing up of mucus.
2 2d. 600 drops. Thereafter, frequent slight coughing up of mucus.
88 Thuja Occidentalis.
At noon, burning in the lower border of tbe right nostril, which was
sensitive to the touch (for half an hour).
23rd. 620 drops. During the whole forenoon he could not get
warm, and twice, while walking, spat blood, the origin of which he sup-
posed to be in the cavity of the mouth, but could not trace it with cer-
tainty. In the afternoon, burning and pressing in the stomach (for an
Lour) ; in the air, tearfulness of the eyes.
24th. 650 drops. In the morning slight coughing up of mucus;
otherwise, he felt well all the forenoon. Afterwards, in the room, a
watery, catarrhal flow came on, and after dinner, frequent, short dry
cough. For a long time, the urine, on emptying the chamber, has
been found thick and turbid, with a sediment at the bottom of the
vessel.
25th. No dose. In the forenoon, an especial feeling of malaise with
general discomfort. He frequently coughed up thick mucus, and had
pain in his stomach and heaviness in the right foot.
26th. 700 drops. During the night, excellent sleep. In the morn-
ing, immediately after the dose, emission of flatulence both upward and
downward. He subsequently observed slight burning on the inner side
of the right lower leg. After breakfast, weakness in the stomach with
confluence of saliva into the mouth. While seated at his writing-ta-
ble he felt the influence of the drug spreading through his system, and
he had no doubt that if he remained quiet, manifold symptoms would
soon make their appearance, but he was obliged to go out, and the de-
velopment of the effects of Thuja was always hindered by bodily move-
ment. At ten in the forenoon, slight burning in the stomach and in
the eyes, slight squeezing about the anus, and short accesses of drawing
in the right arm and leg. In the open air he felt well. After eating
ices, scraping sensation in the throat, unpleasant taste in the mouth, and
constriction in the region of the os hyoides. In the evening, tobacco-
smoke, reading and writing by candlelight produced either burning in
the eyes or cough, an intimation that the catarrhal symptoms were the
effect of the operation of the drug.
27th.' On waking, the eyelids were slightly agglutinated. Some
thick mucus was thrown off by slight coughing, and after a papescent
stool, slight burning in the anus was manifested.
The dose of 725 drops produced, after breakfast, an unpleasant, resi-
nous, constrictive taste in the mouth. As he was much in the open
air no other symptom was developed except frequent sneezing.
28th. In the morning, coughing up of thick mucus again. Immedi-
ately after taking 750 drops, tearing in the tendinous aponeurosis on.'the
skull (for some minutes) ; in the forenoon, frequent light cough with
raising of thick mucus; at noon, great excitement in the genital organs
especially tickling in the prepuce and glands.
Z. remarks : " In my case, Thuja operated in a striking manner upon
the hemorrhoidal vessels ; for I felt in them, at times, congestion and
then again, such a slimness, I might say emptiness, that it attracted my
observation even when I was not paying attention to that quarter • and
Prof. Von Zlatarovich's Provings. (65.) 89
this alternation of sensations frequently took place twice or three times
a day."
29th. 775 drops. No symptoms the whole forenoon. After dinner,
sleepiness, feeling of coldness, especially in the feet; a boring stitch on
the right side of the under-jaw ; a couple of erections, and on the emis-
sion of some very dark colored urine, burning in the urethra; late in
the evening, when visiting the privy, two flying, very painful stitches
low down in the left side of the chest.
30th. In the morning, he several times coughed up thick mucus.
After taking 800 drops, burning in isolated spots under the skin, par-
ticularly on the right side of the chest. Towards noon, while walking
in the open air, a sudden, flying stitch darted through the urethra,
came out from the bulbus, pressed almost to the middle of the urethra,
and was so violent that he was unconsciously obliged to bend over. At
five in the evening, a laming drawing of short duration in the right
shoulder and in the thumb of the right hand ; soon after, tearing in the
palm of the hand near the wrist (for half an hour). At half past eight,
he was seized in the street with general malaise and such universal de-
bility, with weakness in the stomach, that he took a small glass of
cordial at a coffee-house. After a while he felt better again, but about
10 o'clock he felt an indisposition by no means easy to describe in
words ; his mind was at the same time wholly undisturbed. It was a
long time before he could go to sleep, and he awoke in the morning
earlier than usual.
On the 31st and the two following days he took no medicine.
31st. In the forenoon, burning in the anus; at 7 in the evening, vio-
lent heartburn. Notwithstanding the shortness of the preceding
night's rest, he felt, all day, no tendency to somnolency. The urine was
voided very seldom. On the following night, a good sleep.
February 1st. In the morning, frequent hawking up of mucus, sneez-
ing, slight agglutination of the eyes, and burning in the right lower leg.
2d. After rising, drawing tearing in the right arm, especially along
the course of the ulnar nerve, in the right thigh, in the right zygoma,
and in the right side of the chest. After a little while, these symptoms
passed off and appeared, but weaker, in the left side of the body.
3d. In the morning, coughing up of mucus and a single sneeze. An
hour after 850 drops, dulness in the head, on the right side of the fore-
head, continuing an hour, and dryness of the nose. After dinner, slight
burning in the stomach, heaviness and weariness of the legs with dul-
ness of the head, and indisposition to any kind of intellectual labor.
The eyes secrete much gum; the face is wan and the appearance bad all day.
4th. No dose. In the morning, slight dulness of the head; short
drawing tearing, now here, now there, but always on the left side of the
body. In the evening, burning of the eyes as if the room were smoky
(for an hour). Subsequently, debility of the legs, and on writing, a
return of the burning of the eyes. The secretion of urine is very spar-
ing ; and the urine itself soon becomes thick and turbid by standing,
and deposits a copious, clayey sediment.
90 TJiuja Occidentalis.
5th. 875 drops. Thereupon, emission of much flatulence ; slight
pressing on the inner side of the right knee ; transient drawing in the
left ancle, afterwards in the right thumb, and finally on the radial side
of the right upper arm, where the pain disappeared after half an hour ;
slight griping in the intestines, with the feeling as though they were
pinched with the fingers in a circumscribed spot, now here, now there:
on smoking a cigar, the dryness of the nose, which had been already
often remarked, came on, and the mucus hawked up had an unpleasant,
sharp, resinous taste. These symptoms vanished in the open air ; but
in walking against the wind, his eyes continually watered, which had
already been frequently remarked to be the case, but had not been spe-
cially attended to by the prover. After dinner, great inflation of the
abdomen (for an hour) and a couple of gripes in the intestines. In the
evening, slight itching and pressing in the anus.
6th. 900 drops of the tincture. Immediately after the dose, two
sneezings, which seemed to be excited by a vapor rising from the sto-
mach into the nose ; then a couple of short, dry coughs, and slight
burning on the dorsum of the right foot. The eyes were somewhat
agglutinated and watery in the open air. During the lecture, his voice
was hoarse with frequent inclination to haw T k. On coming into the room
from the open air in the afternoon, he had, for some time, painful thump-
ing and roaring in both ears. An evacuation, followed by violent press-
ing, was unsatisfactory.
7th. 925 drops. Immediately afterwards, dischaige of flatulence up-
ward and downward, burning externally over the lower ribs of the right
side ; then, burning in the stomach, with eructations with the taste of
Thuja during the whole forenoon. Burning in the stomach again at
dinner, which was eaten with appetite (for an hour). For several
days past he has noticed that while he is smoking a cigar, seated at
the writing table, he is obliged to cough, dry and interrupted, which
was not usually the case. In the evening, on eating fish, pressing and
burning in the stomach.
8th. 950 drops. Soon after, inclination to cough, and burning in
the throat on the left side near the larynx, which afterwards extended
towards the left ear, with more of a feeling of soreness, and soon after
disappeared. Slight constriction and compression of the lower half of
the chest, and transient stitchy pains on both sides of the thorax extend-
ing to the armpits. Towards noon, burning at the anus, and in the
right leg. He felt well in the air. After dinner, slight burning in the
urethra when urinating. In the evening, burning and stinging in the
edges of the eyelids (even the smoke of tobacco burns in the nose), with
sticking in the nape over the joint of the atlas (for half an hour). ' The
following night, he slept well, and sweat, on awaking, so strongly on
the inner side of the thighs and legs, that the skin was completely
wet, while the rest of the body was dry. (Compare Dr. Huber's
proving.)
9th. Z. concluded his second experiment by taking 1000 drops of
the tincture. After the dose, burning in the stomach (for half an
Prof. Von ZlatarovicVs Provings. (66.) 91
hour) ; then, feeling of coldness over the whole body, in a warm room,
especially in the hands ; rumbling land slight griping in the intestines ;
somewhat later, creeping shudderings, particularly in the back, with
hot face ; heaviness of the eyelids, with slight burning of the eyes and
heat in the right ear. The breathing at the same time was easy, and
the passage of the air through the nose free. The temperature of the
open air 3° R. (39° F.) affected him so unpleasantly that he trembled
from head to foot with cold. After dinner, transient pressing headache
in the vertex ; laming drawing in the right armpit, coming on by fits;
occasional drawing in the right thumb.
10th. His voice was hoarse during his lecture, and his throat so
choked with mucus that he was frequently obliged to hawk. After
dinner, burning of the eyes again, and somnolency also ; slight compres-
sion and crawling externally on the occiput. After a short and very
refreshing nap, burning in the stomach, eructations of wind, discharge
of flatulence, frequent dry cough.
11th. In the morning, after a hard scanty stool, pressing and burn-
ing at the anus ; also, soreness in the bend of the right arm when ex-
tending it (the whole forenoon) ; pressing headache on the vertex and
in the temples (the whole evening) ; feeling of coldness, especially in
the hands and feet, and on the anterior surface of the thigh down to
the knee, when seated in the warm room.
12th. In the morning, coughing, with raising of mucus. In the fore-
noon, there was a return of the soreness in the bend of the arm, but in
a less degree than yesterday.
(66.) Third proving with the 10th dilution.
Z. now instituted an experiment with the diluted Thuja.
On the 12th of February he tasted the 10th dilution, which had
been provided for the proving, in order to ascertain if he could discover
the taste of Thuja in it, which was not the case. Thereafter, in the
course of scarce a couple of minutes, the same troublesome dryness in
the nose came on which had been perceived on the third of the month,
and remained for half an hour. In the afternoon, he perceived burning
and pressing in the stomach (for an hour).
13th. 10 drops of the 10th dilution, which had been previously
shaken for five minutes with two ounces of distilled water. In the af-
ternoon, burning in the stomach (for an hour), and in the evening,
pressing in the hcemorrhoidal vessels.
14th. The same dose. After dinner, sleepiness, and on lying down
on the couch, instead of the expected slumber, painful, cold running
from the nape, over the back, down to the sacral region, which were
increased by every movement of the body, and soon disappeared after
rising.
15th. For the last time, Z. took 10 drops of the 10th dilution im-
mediately before breakfast (cafe au lait). Shortly after he perceived a
sharp taste in the mouth, and had eructations with the taste of Tlmja.
92 TJiuja Occidentalis.
He remarks at this point : " I must confess that I am not in a situa-
tion to account for this symptom. How should it be possible for ten
drops of the 10th dilution of Thuja, drunk in two ounces of water, fol-
lowed by a breakfast of bread and coffee and the smoking of cigars, to
affect the gustatory nerves ?" *
The drawing in the right shoulder also came on for a little while.
After dinner, he was again annoyed by the dryness in the nose, already
often described, and burning on the tongue ; in the evening, burning in
the stomach.
16th. An entirely new symptom made its appearance. -As he was
going to dinner, there was a sudden sparkling before his eyes, and a
multitude of black shining points swam before them, so that he could
not clearly make out surrounding objects. After a while this symp-
tom disappeared ; first from the right eye.f
26th. Eleven days after the closing of the proving. In the evening,
tearing and laming drawing in the left axilla, which on the following
day extended to the right shoulder, where it remained an hour. On
the same day he perceived, for a short time, a constrictive feeling in
the back between the scapulae, which somewhat hindered respiration,
and also motion of the arms. Afterwards he had a feeling in the in-
ternal canthus of the right eye, as if a grain of sand had fallen into
the eye ; this continued until bed-time, and rendered the movement of
the eyelids somewhat painful, though no objective alteration in the ap-
pearance of the organ could be detected.
28 th. The eye was entirely restored ; but in the morning, a pressing
headache in the region of the vertex came on for a short time, and
returned in the evening, accompanied by burning in the stomach.
No other effects of the Thuja were remarked by Professor Von
Zlatarovich. J
Q.
(67.) Zlatarovich'' s proving of the tincture of Thuja on a
young woman.
Catharina Ratmayer, 23 years old, unmarried, thin, of a nervous
excitable constitution, suffered when a child from scaldbead, and from
worms. She was chlorotic from her twelfth to her nineteenth year.
The catamenia first appeared in her fifteenth year ; but during the first
year, they appeared very irregularly, and even at the present time, are
* la our opinion, this taste of Thuja is to be attributed, not to the ten drops of
the 10th dilution, but to the 40,000 drops of the mother tincture which had been
previously taken, which had penetrated, and, so to speak thujacised the whole
body. A new reaction followed the new and almost immaterial dose and that
might disengage a perceptible portion of the previously taken mass. — Mayrhofer.
t Compare Dr. Huber's proving.
X We must give this bold and persevering experiment the highest tribute of our
acknowledgment and admiration. — Mayrhofer.
Prof. Von Zlataroviohb s Provings. (67.) 93
sometimes absent for two or three months, especially on any violent
mental excitement. They appeared last on the 23d of September, and
continued for six days, which has been their usual duration for some
time past. She has suffered for a year with accompanying cramps in
the abdomen. She has had for some years a fiat, dry tetter on the
chin and lips.
1844, Oct, 17th. She began the proving of Thuja with ten drops of
the tincture, taken fasting in water, in the morning. Two hours after
she perceived heat and vertigo (for half an hour).
18th. 15 drops. In the forenoon, pressing in the stomach.
19th. 20 drops. After dinner, transitory coldness over the whole
body.
20th. 30 drops. She felt well during the day. In the evening,
chilliness for several hours, passing into heat on lying down.
21st. 35 drops. No symptoms.
2 2d. 40 drops. In the following night, pain in the stomach, with
nausea and vomiturition (for an hour).
23d. 45 drops. Pressing headache through the day, beginning on
the right side, afterwards extending over the whole head.
24th. 50 drops. In the forenoon, eructations with the taste of the
drug and slight headache for a couple of hours.
25th, 26th, and 27th. 55, 60, and 65 drops. No symptoms.
28th. 70 drops. Coldness all day ; cutting above the navel, ex-
tending into the sacral region ; before bed-time, difficult respiration
with pressure on the chest, by reason of which she could not get to
sleep for a long while.
29th. 80 drops. In the morning, on waking, very violent pressing
aching in the forehead, lasting all day. The menses, which should
have appeared on the 25th, came on, for the first time, to-day, but un-
attended with colic.
The following six days passed without taking any of the drug.
During the first two, she had continual headache, copious eructations
of wind, and wandering, drawing pains in the hollow teeth. On the
1st of November she was well. On the 2d she had, in the morning, a
three hours' headache, at one time in the right, at another in the left
temple, and again in the vertex. On the 3d, the catamenial flow
ceased ; it had been less than usual.
4th. 85 drops. After breakfast, exceedingly violent colic, and tran-
sient cutting and rumbling in the intestines.
5th. 90 drops. A return of yesterday's colic, but less violent; ac-
companied by weariness and general weakness, with heaviness in the
feet and general feeling of discomfort. She felt as if she were threat-
ened with a severe attack of illness.
6th. She awoke with a very violent headache, and took 95 drops.
During dinner, very severe, but very transitory colicky pains came on
suddenly, and also frequent creeping coldness, as during a fever.
On the following two days, 100 and 105 drops produced no symp-
toms.
94: Thuja Occidentalis.
9th. 110 drops. In the forenoon, feeling of coldness ; in the after-
noon, frequent feverish alternations of cold and heat.
10th. 115 drops. Slight headache all day.
On the next two days, 120 and 125 drops produced no symptoms.
13th. 130 drops. She felt all day weak and debilitated.
14th. 135 drops. Violent tearing on the left side of the head, and
in the teeth of that side.
15th. 140 drops. For four hours after the dose, she was as if stu-
pefied, sleepy and weak ; the rest of the day well.
16th. 145 drops. She then ceased taking the remedy for sixteen
days. During this time the results were as follows :
On the day of the dose, stupefaction again and sleepiness, which did
not last so long, however, as on the previous day. In the afternoon,
frequent eructations of wind, and pressing in the stomach, which ex-
tended through the throat into the fauces. Late in the evening, on go-
ing to bed, tearing on the right side of the head, and itching over the
whole skin, especially on the abdomen, as if she were covered with an
eruption. Painful inflamed tubercles appeared on various spots on the
body.
17th. In the forenoon stomach-ache and melancholy state of mind;
in the afternoon, more cheerful humor. This alternation of humors has
already manifested itself for some days past.
18th. In the forenoon, pains in the stomach ; hawking up> of mucus;
stoppage of the nose, with nasal sound of the voice, biting on the whole
body; in the evening, sticking in the head, and transient tearing in the
left hand.
19th. In the afternoon, tearing in the teeth of the left side, and af-
terwards a very restless night.
20th. Very severe catarrh with increased secretion in the air pas-
sages, painful swallowing, and sticking in the head.
These symptoms disappeared by degrees on the following days, and
she continued the proving on the 2d of December, by taking 150 drops.
Soon after the dose, stupefaction (effect of the alcohol ? M.) and ex-
treme drowsiness during the whole day.
Dec. 3d. 155 drops. Stupefaction, sleepiness and frequent eructa-
tions of wind. • *
4th. 160 drops. After dinner she was very thirsty, and so inflated
that she could not bear the pressure of the strings about her body.
5th. 165 drops. The same symptoms.
6th. No dose. Extreme melancholy.
7th. 165 drops. After awaking, very violent headache, lasting all
day and disappearing on the next day on which the dose was omitted.
On the next three days, 170, 175, and 180 drops produced no symp-
toms.
12th. 185 drops. After dinner, extreme thirst; in the evening
colic.
13th. 190 drops. Colic with two fluid evacuations, great thirst and
cold over the whole body, with drowsiness.
Prof. Von Zlatarov ch's Provings. (67.) 95
14th. No dose. She awoke with sticking in the left side of the
head, which soon went off; but the head was dull all day. She had
also drawing from the head over the nape and the back to the sacral
region, and complained of general weakness with heaviness and cold-
ness of the feet, and in the evening, of general burning heat, where-
upon restless sleep followed.
15th. She awoke with headache, and took 195 drops. In the even-
ing, coldness in the back with alternations of heat. She has made
the observation for several days past, that on bowing, she has sticking
in the left side of the head, even if she were not just then suffering
from headache.
16th. She closed the proving with 200 drops. The headache with
which she awoke lasted three hours, and after it had ceased, sticking
pain came on when bowing, but on the right side of the head. After
dinner, pressing in the right side of the chest, during the whole after-
noon, accompauied in the evening by sticking, which extended into the
sacral region. Daring the whole day, coldness, especially in the bade,
with general weakness and sensation of weariness. In the evening,
manifest fever symptoms developed themselves, as : headache, heat of
the skin, full, accelerated pulse, besides sticking in the right hypocon-
drium (especially during respiration), which extended into the sacral
region. She went to bed on this account, and general heat came on,
succeeded by quiet sleep.
1 7 th. There was no fever, but she felt weak. She has had no evacuation
for two days past, and n© appetite ; a bitter mucous taste in the mouth.
The pains in the chest are completely gone ; borborygmus is frequent
in the intestines ; in the evening, sticking in the head, and pressing in
the left side of the chest. These symptoms are diminished by an evacu-
ation. The sleep was disturbed during the night by heavy, harassing
dreams.
18th. In the morning, headache and cough, with copious excretion
of mucus; catarrh and bitter taste the whole day, thirst with alterna-
tions of heat and cold, the latter especially in the dorsal and sacral
region, with hot head and face. On going to bed, pressing on the chest,
with difficult breathing and sticking in the side. Before midnight,
coldness; towards morning, warmth; finally perspiration.
19th. On rising, violent sticking in the head, especially on moving ;
great accumulation of mucus. In the forenoon, alternations of heat
and cold. Towards noon, the headache became very severe, and re-
mained so for half an hour; there came on then, drawing in the small
of the back (aggravated while seated), stoppage of the nose, burning of
the eyes, frequent eructations of wind, difficult, almost panting respira-
tion, violent cough, with raising of mucus. In the afternoon, slight
colic, with borborygmus and inflation of the abdomen. In the even-
ing, general chilliness without thirst. The pulse beat at the rate of
100 in a minute, was full and hard. Several inflamed tubercles ap-
peared in the face. Her food tasted insipid.
20th. During the night, in which she continually suffered from se-
96 TJmja Occidentalis.
vere coldness, the catamenia appeared, ten days earlier than usual. In
the morning, she felt very ill ; her head was dizzy as if stupefied, her
mouth tasted very bitter ; all her teeth seemed to be loose ; she fre-
quently coughed up mucus as thick as lard. In the forenoon, she felt
pretty well. Towards noon, alternations of heat and cold came on,
with weakness to the extent of falling. In the afternoon, she felt well
again except a slight headache. Catamenia very scanty. She observed
for several days past, that she becomes hot at dinner, and her body is
covered with perspiration.
21st. During the night, she slept extremely restless. So bitter was
the taste in her mouth that she was obliged to get up in the night and
rinse out her mouth with water. She awoke at about three in the
morning, and could sleep no more on account of heat. Afterwards, a
chill came on, and in the morning a very violent headache, lasting all
day. Before dinner, she felt weak and sleepy, and was cool over the
whole body. She felt better in the evening.
2 2d. In the morning, headache, but less than yesterday; frequent
spitting of saliva and mucus, with hollowness at the stomach and in-
sipid taste. General feeling of discomfort ; she looks very ill, is weak,
depressed in body and mind, and is somewhat bloated in the face. To-
wards noon, an attack of coughing, with raising of tenacious mucus,
vomiturition and strangling ; after this she felt ill and weak for half an
hour, and had a return of more violent headache. At noon every thino-
tasted insipid. In the afternoon, when walking, great heat, weight up-
on the chest, breathlessness and occasional dry cough, with sticking in
the head. In the evening, coldness in the back, with accompanying
heat in the head, with great drowsiness and thirst ; at night quiet sleep.
23d. In the morning, bad taste in the mouth; less sticking in the
head than yesterday ; she feels very hot and weak, and is frequently
obliged to sit down to rest, although she insists upon it that she is bet-
ter to-day than for some days past. She coughs very little, and has
shorter breath than usual, with weight on the chest ; her urine is co-
pious, she has had no evacuation for two days. In the evening, chill
again followed by heat, thirst and sleepiness. Pulse 1 20, full and hard ;
she is very low spirited.
24th. _ The same symptoms appeared, accompanied by tearing in the
hands; in the evening, feverish pulse with headache ; a good night's
rest.
25th. In the morning, headache ; also violent tearing in the nape,
which extended into the axilla (which ? M.) and there remained during
the whole day. The upper arms are painful, and so weak that the
patient can, with difficulty, hold them up long enough to arrano-e her
hair ; she trembles in hand and foot, looks pale and earthy, is exceed-
ingly out of tune, sad and disposed to weep; respiration very short on
walking, cough dry, abdomen very much inflated, taste bitter, increased
thirst ; alternations of heat and cold ; pulse not so much accelerated
nor so full as yesterday. A hard evacuation.
20th. The patient feels so weak and powerless that she cannot leave
Prof. Von ZlatarovicWs Proving (67). 97
her bed. Her head is very dull ; she is as it* stupefied and dozes much ;
her tongue is somewhat furred and half dry ; pulse moderately accele-
rated, full and hard. To these symptoms were added cough and tear-
ing in the left shoulder. This state of things, in connection with a very
bad countenance and extreme prostration and depression of spirits, gave
Z. reason to apprehend the development of a nervous fever (? M.), and
he gave her a drop of Puis. 30. She continued the same for the rest
of the day ; she had occasional naps during the night, but they were
disturbed by tearing in the left axilla and slight colic.
27th. In the morning, the same state of things, but in a somewhat
diminished degree. Tongue dry at the point. In the afternoon, bitter
taste, redness of the face with cool extremities, irritable humor. She
had Cocc. 30, one drop. In the evening, copious, general perspiration,
with diminution of all the morbid symptoms, and tolerably good sleep
at night.
28th. In the morning, striking abatement of all the symptoms.
The skin is agreeably moist, the pulse less accelerated, the feelings less
gloomy ; the tongue is still somewhat furred, and the tearing in the
left shoulder is still present, but at times, it goes to the right shoulder
and nape. She begins to feel a little appetite, and has had two
stools; but she still feels very weak, dozes much, and speaks very
slowly and monosyllabkally. She had Cocc. 30, one drop in a tum-
bler of water, with directions to take a tablespoonful every two hours.
The improvement continued during the day, and she had a good
night.
29th. The pains are considerably diminished; the fever is slight,
tongue moist, taste natural, mind cheerful. At night, sleep and copi-
ous perspiration. Cocc. continued.
30th. In the morning, the patient is exceedingly ill-humored, speaks
but little, and keeps her eyes continually closed. For the rest, she
complains of no pain, her pulse is but slightly accelerated, and there is
nothing further worthy of remark. Z. gave her Rhus 24. She sleeps
much during the day and has no appetite ; the tongue is moist and a
little furred ; urine copious and yellow. She slept and perspired at
night.
31st. With the exception of great weakness and prostration, no mor-
bid symptoms appeared to-day. In the afternoon, the nose bled, after
which her head was much relieved.
" It must be observed," remarks Z. in his relation, " that both those
about the patient, and she herself had noticed that she was better and
worse on alternate clays, indications of a tertian type."
" I must confess," pursues he, " that I have no hesitation whatever
in considering this whole attack, as it appeared, as caused by the Thuja.
Had it been a natural idiopathic affection, there would have been a
greater harmony in the symptoms. (? Ed. Oest. Zcit.) The febrile
symptoms, however, stood in no relation to the extraordinary debility ;
thero were no abdominal pain-, no diarrhoea, no delirium, no metoris-
98 Thuja Occidentalis.
mus, nor any of those symptoms which usually indicate the existence'of
a typhoid disease." *
1845, Jan. 1st. After a good night's rest, the patient, with r the
exception of general weakness, which was still present, felt well. Her
appetite returned ; she was not so depressed in mind as on the prece-
ding"days ; but her speech is still very slow and drawling. She took
Ignat. 24. At noon she was for a short time out of bed, and re-
mained well during the afternoon.
2d. The catamenia appeared without any morbid symptoms, but
lasted only one day.
15th. For the first time the convalescent went into the opeu air,
which seems, nevertheless, to have been too soon ; for on the 16th
chills, want of appetite, peevishness, and a small weak pulse again
made their appearance. She now took Nux vom. (in what dose? M.)
An hour after, a shaking chill, lasting half an hour ; heat came on over
the whole body, preceded by a gradually increasing warmth. She
was so weak that she was obliged to remain in bed the whole day.
She had a thickly coated tongue, with bitter taste, but little appetite,
and for two days past no evacuation. The febrile symptoms were slight.
The Nux was continued. The next day she was better throughout,
tongue cleaner, appetite returned, had a stool, increase of strength.
The convalescence now steadily proceeded without any further medica-
tion, but it was a full month before she regained her former health.f
R.
(68) Dr. Zoffls Proving with the Tincture.
Franz Zotli, medical student, 24 years old, choleric-phlegmatic
(? M.) temperament and apoplectic build; at 15 had the typhus; a
year ago, was treated for ten days at the medical clinique for an in-
flammation of the lymphatic glands of the right arm, which had come
on in consequence of intoxication with Cyanide of Potassium ; in other
respects was entirely well.
Zoth's proving produced very few results, notwithstanding he took
5000 drops of the tincture within three months.
1844, Oct. 15th, 16th, 17th and 18th. No effects were perceived
from 5, 8, 11, and 14 drops of the tincture.
19th. 17 drops. He perceived single stitches in the right frontal
region. On the following two days 20 and 23 drops produced no
symptoms.
22d. 26 drops. A cough came on, which he regards as having been
possibly caused by an exposure to cold.
* We do not for an instant doubt but that the above described attack was the
result of the doses of Thuja ; we recognise in the instability of the symptoms, in
their evident discordance, and in the irregularity of the course of the disease, the
fundamental characteristics of the drug. — Mayrhofer.
t What became of the tetter on the chin ? — Mayrhofer.
Dr. Zotfrs Proving (68) 99
The cough continued on the following two days, on which 29 and 32
drops were taken.
25th. 40 drops. To the cough was added swelling of the throat,
which continued during the following three days, on which 50, 60 and
65 drops were taken.
From the 29th of October to the 6th of November, Z. increased his
dose ten drops each day, so that commencing with 70 drops on the first
day, he took 150 on the last.
The prover's diary contains nothing remarkable for these ten days,
except that the excretions* were increased in quantity, and were less
consistent ; which remark will also apply to the previous days.
From the 7th to and including the 22d of November, he continued
the Thuja in a similar ascending scale of doses (ten drops a day), and
took on the last named day 300 drops of the tincture. (He omitted
the dose on the 16 th.) The results were as follows :
7th. Painful throbbing in the base of the glans (for four minutes) ;
afterwards, pains (of what sort ? M.) in th*e lower half of the spinal
column and in the sacrum, continuing and aggravated by bending the
body ; also in both knees. These pains continued also during the fol-
lowing day, and were attended by great general weariness.
9th. Having taken much exercise this day the pains became less ;
on the 10th, however, became more violent, decreased by degrees on the
following days, and finally ceased on the 16th, on which day he took
no dose.
17th. These (undescribed pains ! M.) returned again, and were es-
pecially violent in both hips, weaker in the sacral region and knees.
18th. They ceased in the sacral region, but continued in the hips and
knees.
19th. An eruption upon an inflamed surface appeared on the left
side of the chin.f
22d. Violent buzzing in the ears, lasting several hours.
From the 23d of November to the 5th of December, the Thuja was
omitted, and all the previously described symptoms vanished.
From the 6th to and including the 20th of December, he again
continued the experiment, taking on the first day 310 drops, and daily
increasing the dose by five, until he arrived at 380 drops on the last
day. He observed no effects.
From the 22d of January to and including the 2d of February, he
made a short experiment with dilutions (without saying which ! M.) and
likewise perceived no alteration in his sensations.
* Urine, faeces, and perspiration 1 — Mayrhofer.
+ Its form ? It is indispensable, in describing objective symptoms, that their form
and duration should be noted with the greatest accuracy. — Mayrhofer.
100 Tim) a Occcidentalis.
S.
(69) Dr. Zwerinds Proving with the Tincture.
Dr. Zwerina, thirty-six years old, perfectly healthy, and of a san-
guineo-choleric temperament, proved the Thuja as follows :
1845, January 23d. He began with forty drops of the tincture pre-
pared according to Hahnemann's direction, which he took at nine
o'clock in the forenoon, an hour after breakfast, and observed no other
result than that during the following night he was obliged, contrary to
his usual habit, to rise three times for the purpose of urinating. The
urine passed was a straw-yellow and amounted to a full measure.
On the following day he took nothing, and observed no symptoms
which he could ascribe with confidence to the drug.
25th. Thirty drops, taken early at about nine o'clock. At noon,
slight burning in the urethra, leaving behind a voluptuous feeling, espe-
cially after urinating. The quantity of water passed was again increased
during the night; it was clear and straw-yellow. Sensation of great
fatigue in the groins. His appetite was small, and his customary
morning evacuation did not take place.
26th. To quicken the action of the remedy, the impatient prover
took fifty drops morning and evening. Immediately hereafter, burning
in the urethra and copious urine ; the customary daily evacuation ab-
sent. Disquieting dreams, frequent urination, and four pollutions,
disturbed, an unrefreshing night's rest. Sleep came on late, an unusual
occurrence with him.
27 th. These symptoms did not deter the prover from taking 100
drops this day, fasting. Thereupon he experienced headache in the re-
gion of the forehead and eyebrows, such as usually precedes a catarrh ;
ill-humor, lasting all day ; want of appetite, with frequent eructations ;
repeated shuddering, beginning at the head ; slight burning in the region
of the kidneys, ceasing after an hour, and followed by still more copious
urine, accompanied by burning. The feeling of fatigue in the region
of the groins passed into a drawing pain extending into the glans penis,
and the inguinal glands were perceptibly swollen. A general feeling
of malaise, toith internal chills, came on, and instead of his usual
cheerfulness, peevishness. For three days he has had no stool.
28tb. Notwithstanding this, he again took 100 drops early, lasting,
" and now," says he, " for the first time, the drug fairly mastered the
health that had so far defied it."
An hour after the dose, the burning in tjie renal region increased,
and was accompanied by drawing along the urethra up to the vesica ;
the urine diminished in proportion as the burning in the ureters in-
creased. The glans began to grow moist and to secrete a thin mucus.
In the evening he had a slight chill, attended by dryness of the throat
with painful deglutition, vomiturition, and such a feeling of illness
that he was obliged to go to bed before the time. His interrupted
Dr. Zwerina?s Proving (69). 101
sleep was full of anxious dreams, and he continued the fourth day
costive.
He was now so well satisfied with the pathogenetic effects of Thuja
that he dropped the experiment. By degrees his abnormal symptoms
disappeared ; first the headache, then the dryness of the throat, and
lastly the renal affections ; on the first of February, after a constipation
of eight days, he had a copious, hard evacuation.
According to this proving, Thuja manifested its especial power in the
urino-genital system, and it is much to be regretted that so promising an
experiment should have been closed after the exhibition of only 360
drops.
T.
The following physiological proving of Thuja, by our associate, Dr.
Holleczek, practising physician in Klagenfurt, has only reached us while
these sheets are going through the press. It contains, for the most part,
only subjective symptoms, and adds scarcely any new lines to the por-
trait of the Thuja sickness depicted by the experiments already de-
tailed.
Dr. Holleczek has a strong constitution ; had an intermittent fever at
twelve years old, but was othei-wise well until his twenty-second year.
He then had a slight attack of pneumonia, and was perfectly restored
in a few days by homoeopathic treatment He has had no other sick-
ness. At the time of his first experiment he was twenty-five years old.
The symptoms below follow in chronological order.
(TO) First Proving with the Tincture.
1838, September 2d. He drank at one draught a half ounce of the
strong tincture of Thuja prepared according to Hahnemann's directions,
having first well mixed it with eight ounces of water.
Violent pressing headache in the region of the vertex ; sensation as
though something were squeezed out at both ears ; heat in the face
(immediately) ; feeling of heat in the whole chest ; stitches in the tem-
poral region, in the elbow and heels.
Pressing pain in the occiput ; head pains as though the head
were stuck through from one temple to the other ; slight eructations
(all day).
Stitches in the metacarpal bone of the little finger.
Stitches in the scrobiculus cordis; sticking beating in the middle of
the right side of the chest ; stitches in the cardiac region ; pressure under
the sternum ; sticking in the pit of the throat.
Drowsiness ; violent pressing pain in the occiput ; feeling, when
turning the head one side, as though apiece of lead lay in the brain.
Stitches from the spine through the epigastric region, forward to the
pit of the stomach ; frequent sticking pains in the right shoulder-joint ;
repeatedly during the day, a cutting pain, perpendicularly through the
middle of the chest from below, upward as far as the pit of the throat ;
102 17mja Occidentalis.
sticking pains in the forehead ; extremely violent sticking pain in the
metatarsal bone of the middle toe of both feet; pressure on the right
side near the scrobiculus cordis, as if from a foreign body, with frequent
stitches, worst in the morning.
Itching on the inner surface of the prepuce ; extremely violent pain
in the middle toe of the right foot ; several stitches in the interior of
the right ear ; painful, frequently repeated stitches in the right testicle ;
dreadful tearing pains, which darted like lightning hither and thither
through the urethra, with simultaneous violent stitches in the anus (in
the afternoon when seated).
_ Quivering twitching from the ear to the left corner of the mouth,
sticking pains in the left shoulder-joint; tearing pains in the metatarsal
bones of the right foot ; dull sticking pain in the metacarpal bone of
the middle finger of the left hand ; sticking in the great, fourth, and
little toes of the left foot.
Pressure in the larynx ; sensation of burning and constriction of the
larynx ; tearing pains in the under jaw, which began on both sides, in
the region of the joint, ran forward together in a line to the chin, united,
and instantaneously disappeared.
_ Painless twitching of the middle finger of the right hand ; very painful
stitch through the upper part of the left breast from before backwards,
which immediately disappeared, and left a feeling of twitching in the
spot : tearing pains in the bones of the left fore-arm and wrist, stitches
in the point of the third finger of the right hand ; sticking in the sole of
the right foot, from within outwards ; feeling of dislocation in the middle
of the spine, increased on the right side by violent bending of the body.
(71) Second Proving.
September 4th. The same dose as on the 2d.
Pressing headache on the vertex and occiput, with the sensation as
though tfcere were lead in it, aggravated by moving the head and by a
false step, with the feeling as though the brain were loosely moving
about : when lying on the back, knocking in the chest under the ster-
num, extending to the sacrum : while lying "on the right side, many
stitches in the same side of the abdomen, which disappeared on pres-
' sure, and returned on walking in the open air ; in the evening, when
walking in the open air, feeling of fulness and pressure in the occiput;
on moving the head sideways, vertigo.
Constant, painful pressures from within toward the nipples ; painful
pressure in the right abdominal region, which disappeared on making
pressure there with the hand, but became sensible again (during the
whole day) on taking a deep inspiration, or on forcibly expiring : con-
stant tearing pain in the metatarsal bone of the middle right toe •
stitches in both knees when walking.
Cough with the expectoration of mucus when eating ; after eatino-
cough with raising of a tough mucus— sticking headache in the region
of the vertex ; painful tension in the occiput from one ear to the other.
Dr. Holleczeckh Provings (71). 103
Little thirst ; urine with a penetrating odor.
Stitches in the right wrist joint ; boring from without inwards in the
region of the right iliac bone ; sticking in the middle of the sole of the
left foot, from within outwards ; a quick drawing, boring pain through
the fore-arm and the metacarpal bone of the index finger ; painful ten-
sion of the hypogastric region with occasional sticking pains, aggravated
by deep inspiration (in the forenoon with an empty stomach) ; painful
stitches in the skin of the left elbow.
_ Pressing in the middle of the chest upwards into the neck, inducing
difficult respiration ; sticking pains in the region of the heart ; constant
pressure in the middle of the chest, with sticking pains during the at-
tempt to inspire deeply : frequent creeping chills ; pressing pains in the
whole upper part of the chest, becoming much more violent by pres-
sure ; cutting pain from the spine to the pit of the stomach.
Sensation as though the right side of the scrotum had been bruised ;
cutting pain deep in the left side of the abdomen ; sensation when nod-
ding forwards as if the brain were pressed out at the vertex ; sticking in
the right thumb, tearing in the right tarsus and great toe ; cutting in
the left sideof the upper lip ; dull pain anteriorly in the lower third of
the right thigh ; sticking in the bones of the lower leg from the tarsus
up to the knee ; tearing in the scrobiculus ; on bending the body to the
•right side, tearing in the right popliteal space.
Fine sticking in the third joint of the index finger, from within out-
wards; violent stitches in the anterior extremity of the urethra, without
urinating ; sticking in the external malleolus, in the hip-joint, in the
metacarpal bone of the middle finger, on the inner edge of the foot, in
the heel ; dull sticking pain in the joint where the thumb and index finger
are articulated with the metacarpus ; dull sticking in the interior of the
right ear.
Twitching of the muscles on the right fore-arm ; feeling, when seated,
as though the breast were compressed from before backwards, aggra-
vated by stretching the body; painful stitches in the interior of the left
chest ; dull cutting under the left shoulder-blade ; cutting pain on the
left side near the scrobiculus.
Stitches in the left testicle (for eight days) ; when coughing, dull
sticking pains in the right inguinal region ; violent sticking in the region
of the spleen, during a meal ; very violent stitches in the toes, noon and
evening, on bending the body to the left side (on the seventh day). •
Sticking pain in the liver, when walking ; sticking pains in the right
elbow ; sticking in the metacarpal bones of the left hand ; oppression
of the chest ; necessity of frequent deep breathing ; dull sticking pain
in the left parietal bone ; sticking pain in the brain from the neck up to
the vertex; stitches through the brain from below upwards, especially
when coughing; stitches in the left ala of the nose; vague stitches in the
left lung ; burning in the forepart of the urethra, without any flowing ;
drawing sticking pains in the liver ; cutting pains in the rectum.
104 Thuja Occidentalis.
(72) Third Proving.
October 31st. Eight drops of the tincture of Thuja in a table-spoon-
ful of water.
Sticking in the scrobiculus ; sticking beating in the fossa navicularis
of the urethra (coming on daily for two weeks, at irregular intervals,
and frequently repeated in an hour) ; sticking in the region of the spleen
at indeterminate times, but particularly during dinner and supper (at in-
intervals of four days) ; an evacuation early every day, with urging,
although only a small quantity of thin fseces was quickly passed ; after-
wards feeling of inactivity in the rectum.
Vertigo, coming on of a sudden after dinner (while looking up) ;
headache in the occiput ; pressing with stupefaction when moving the
head to one side.
Corroding aching of the right half of the scrotum.
All the diameters of the chest seem to have become shorter : painful
tension in the whole chest when inspiring deeply ; sensation of want of
pliability of the thorax and of insufficiency in the inspired air ; at night
short breath ; necessity to assist by breathing deeply.
Violent cutting in the point of the tongue and on its under surface;
cutting in the upper eyelid ; quivering of the muscles cf the left thigh
just above the knee ; violent pressing pains in the left elbow, as if in
the bone.
(73) Fourth Proving.
November 15th. Fifteen drops of the tincture of Thuja at a doso
in a table-spoonful of water.
Sticking in the middle of the right side of the chest near the sternum
(in a quarter of an hour) ; stitches like lightning transversely through
the chest.
Tearing pain in the tendo Achillis on the right side ; strong exten-
sion of the right knee impossible on account of a sensitive, painful
obstacle in the popliteal space ; the same symptom in the left knee ;
cutting pains through the chest in different directions ; stitches in the
right tendo Achillis.
Twitching pains under the heart ; tearing and sticking pain in all
the joints ; stitches through the zvhole brain from below upward.
Burning when urinating ; burning and sticking in the fore part of
the urethra.
Cutting in the right iliac region ; tearing in the right hip-joint ;
tearing in the left little toe ; violent sticking on the outside of the left
knee ; violent sticking under the right knee ; stitches in the sole and
in the palm ; itching in the rectum after stool ; boring, as of a worm f
in the rectum, from within outwards, after an evacuation.
(74) Fifth Proving.
1840, January 6th. Ten drops of the fourth dilution (5 : 95), in
an ounce of water.
Dr. Holleczeck's Provings (72). 105
Vertigo, when seated, returning as though in pushes every minute
(after half an hour) ; sensation as though the brain were raised several
times in succession ; very painful stitch on the right side near the ster-
num on the fourth true rib, repeated, in only one spot; dull sticking
pain in the left fore-arm, near the elbow ; tearing pain in the right shin-
bone from the knee down, and from the tarsus up to the knee (sub-
sequently repeated) ; sticking pain in the right knee, coming from the
popliteal space ; sticking in the left elbow.
Excessive rumbling in the abdomen ; dull sticking from the right
ear and under the lobule outward ; twitching in the muscles under the
left scapula ; very painful tearing in the right tibia downwards (the whole
day) ; cutting from below upward on the right side near the sternum.
Frequent eructations ; tearing in the left leg downward ; pressure
on the sternum not affecting the respiration ; pressing feeling in the
pelvic region on the right side near the linea alba, as if from a foreign body.
7th. Fins superficial sticking in the points of the fourth and little
toe; continual, dull sticking pain in the left shoulder-joint; a tearing
pain from the ischium through the posterior part of the right thigh, as
far as the popliteal space ; a cutting through the left half of the under
lip, from below upward ; twitching in the integument of the occiput,
on the right side ; violent ringing in both ears ; in the evening, sticking
in the left palm ; tearing in the outer border of the right sole.
(75) Sixth Proving.
January 8th. Fifteen drops of the second dilution [5 : 95].
Dull confusion of the occiput, ending in a pressing headache which
lasted half an hour ; sticking on the right side, near the middle por-
tion of the sternum ; several stitches coming from the interior of the
chest ; twitching in the right ear with sticking pains ; both ears stop-
ped ; tearing in the leg ; stitches in the brain, from the occipital fora-
men upwards ; tearing in the right eyeball ; sticking pain in the left
elbow several times during the day ; tearing in the right eyeball, com-
ing from the brain ; sticking on the left side, near the scrobiculus, from
within outwards ; sticking and ringing in the right ear ; sticking pain
in the right fore-arm near the elbow ; tearing in the metacarpal bone
of the little finger ; frequent tearing in the great toe of the right foot ;
dull sticking near the middle portion of the sternum on the left side ;
tearing pain in the metacarpal bone of the index finger ; dull sticking
in the left frontal region ; cutting in the right shoulder -joint ; stitches
in the right metacarpus and in the left eyeball ; cutting from the point
of the left scapula through the chest to the edge of the middle portion
of the sternum ; stitches in the fourth toe of the left foot, in the left
sole, and in the right thigh.
9th. Early, after rising, ringing in the ears ; sensation of heaviness
in the occiput; cutting under the sternum, which embarrasses the res-
piration ; cutting in the right side of the chest, extending from the
sternum to the right elbow ; very sparing stool, half fluid, with a sen-
106 Thuja Occidentalis.
sation as if the rectum were very inactive ; a feeling in the vertex as
if a nail were driven in there ; very violent cutting in both loins when
walking ; ringing in the ears, frequently during the day.
10th. Cutting in the urethra from the perinaeum forward ; very
violent, dull sticking pain in the right testicle ; tearing in the left knee ;
ringing in the ears ; evacuation slight, not satisfactory ; sticking pain in
the pelvic region on the right side near the linea alba ; sticking in the
splenic region.
11th. Sticking pains in the left testicle, several times during the day ;
tearing in the right carpus ; severe cutting pains in the urethra (perinse-
al region) ; dull stitches in the rectum upwards ; a stitch from the fora-
men magnum through the brain to the vertex ; dull sticking pain near
the lower part of the middle portion of the sternum, on the right side;
tearing in the right leg; no evacuation; cutting in the epigastrium,
from the spine outward ; feeling, when laughing moderately, as though
the thorax were strongly compressed, with shortness of breath ; dull
sticking in the popliteal space impeding the extension of the leg.
12tb. Tearing in the right lower leg ; sticking in the left knee, early,
in bed ; several dull stitches near the scrobiculus on the left side ; tear-
ing in the metacarpal bones of the right hand ; a sticking pain on the left
side from the sacrum to the left testicle ; tearing in the left lower leg.
13th. In the open air, tearing pains in the region of the heart, and
from there into the left scapula ; sticking in the left knee ; tearing in
the left lower leg ; roaring in the ears.
14th. Tearing in both legs and in the right thigh.
15th. Tearing in the right thigh ; ringing in the ears several times
during the day.
16th. Tearing in the right foot.
(76) /Seventh {and last) Proving.
17th. Ten drops of the first dilution in an ounce of water produced
no new symptom. The almost exclusive subjective symptoms which
the prover noted from the 17th to the 20th were summarily as follows :
sticking in and on almost every part of the body — on the vertex, through
the brain, in the eyeball, in the sternum, under the nipples, in the ribs,
through the chest, from the scapula through the heart, in the groins, in
the maxillary bones, shoulder, elbow, and knee-joints, in the ankle and
wrist, in the os ilium, in the thigh, in the calf, in the arm and fore-
arm, in the metacarpal and metatarsal bones, in the tendo Achillis, in
the final joint of the thumb and great toe, at the root of the nails of
the thumb and index finger.
Tearing in the concha, the eyeball, the scrobiculus cordis, the shoul-
der-blade, the shoulder and hip-joints, the thigh, from the ischia to the
knee, in the leg, in the arm and fore-arm ; cutting in the perineal por-
tion of the urethra ; twitching in the flexor of the left thumb in the
right cheek, under the scapula ; sensation of dislocation in the knee and
hip joints (aggravated by walking in the open air); painful oppression
Dr. Holleczectts Provings (78). 107
under the sternum (increased by deep inspiration) and in the inguinal
region ; ringing in the ears fur several hours ; roaring in the ear (early
in bed); increased urgency to urinate ; feeling of compression in the
testicle ; scanty, papescent stool.
U.
Dr. Holleczek also caused three experiments to be made by his sister
Josepha, a healthy, active girl, seventeen years old. Like those of her
brother, they produced for the most part only subjective symptoms.
(77) First Proving.
1840, January 6th. Ten drops of the 4th dilution of Thuja in an
ounce of water. — During the same day, sensation as though the skin
on the temples and forehead were shrunken and hard, continuing two
hours ; drowsiness ; fine sticking in the inner malleolus of the right
foot ; sticking in the region of the spleen, twice in succession, with con-
sequent soreness there ; pressing and fine sticking under the sternum ;
sensation of weakness in both knees (disappearing in the right in ten
minutes, in the left after an hour); sticking in the region of the fifth
true rib on the right side ; great lassitude and weakness in both arms,
with frequent tearing in them ; vertigo ; superficial headache, as if the
skin were rendered tense on all sides ; frequent yawning ; chills over
the whole body ; sticking in the left palm, the right axilla, and near the
pit of the chin ; headache in the forehead, pressing, the whole day ;
pressing in the eyes ; chills in the evening in bed ; several stitches in
the right axilla and temple.
On the following day, repeated tearing in the forehead and sticking
in different parts of the body (elbow, tibia, mammae, chin, scrobiculus,
scapula, shoulder-joints).
(78) Second Proving.
January 8th. Fifteen drops of the second dilution. — The same day,
tearing (in the small of the back, in the nape, over the temple, in the
knee-joiut, in the tarsi, and some of the finger-joints) ; sticking (in the
ear, under-jaw, splenic region, hip-joint, iliac region, in the middle of
the thigh and leg, in the tarsus, shoulder-joint, arm and fore-arm, car-
pus) ; both these feelings, tearing and sticking, most on the right side ;
ringing in the ears ; heaviness and tension in the back ; sensation of
soreness in the scrobiculus cordis.
The symptoms developed on the succeeding days, from the 9th to
the 16th, are little more than a repetition of those already given. —
She had stickings and tearings sometimes in the same parts, sometimes
in others (ear, ear-cartilage, ala of the nose, near the sternum, in the
epigastrium, between the shoulder-blades), and sometimes in all the
limbs (on the 9th, in the evening in bed). She also complained on
the 9th of stoppage of both ears, and on the 10th, of painful soreness
in the middle of the back, and pain as if bruised in the right shin-bone.
108 Thuja Occidentals.
(79) Third Proving.
January 17 th. Ten drops of the first dilution in an ounce of water.
The sixty-six symptoms which the prover perceived and noted during
the experiment, from the lYth to the 21st of January, consist mostly
also of sticking and tearing, now in this and now in that part of the
body — scarcely a spot was intact. The pain seems for the most part to
have been transitory. I only find recorded on the 18th, a sticking in
the left iliac region "lasting all day." On the 21st she had a tearing
in the left fore-arm, shooting from the elbow to the fingers so that they
were suddenly flexed. On the 18th she had, besides sticking and
tearing, " feeling as if bruised in the back and buzzing in the ears."
There is only one objective symptom in addition to the sudden flexion
of the fingers just mentioned, "increased secretion of urine" on the day
of the dose.*
CHAPTER V.
Symptomatology and Characteristics of the TJiuja-Sickness.
The process of deteraiiriatirg the characteristic marks of a remedy,
can, from its very nature, be nothing more than that of throwing into
natural groups the scattered materials afforded us by the provings, and
estimating scientifically the morbid elements thus obtained, in order in
this way to obtain its therapeutic indications and raise the drug to the
rank of a remedy.
In this difficult task three main points, in our opinion, must be kept
in view.
1. The where of the morbid manifestations, that is, the organic sub-
stratum, the locality, the locus in quo of the sickness.
2. The hoio, that is, in what way and after what fashion the
pathogenesis of the drug is developed in subjective and objective
symptoms.
3. The discrimination of the drug-symptoms into subjective and ob-
jective, idiopathic and sympathetic, essential and accidental, constant
and variable, <fec, upon the solid foundation of the physiological proving,
to the exclusion of all hypotheses and learned refinements.
To this end we will now examine the phenomena presented by the
* The experiments which Dr. Frohlich instituted with the Thuja upon two
rabbits, led, unfortunately, to no result. In order to avoid any possible disturbance
from alcohol, he prepared the fresh juice of the arbor vitoe, and for a week several
times moistened with it the left eye, the anus, and a bare spot on the skin of one of
the rabbits, and administered to the other for the same length of time at first one
and finally three coffee-spoonfuls of the juice a day. It is to be regretted that
Frohlich, who has already given us several beautiful drug-provings upon animals
was on this occasion, as he himself says, " obliged by divers circumstances to ab-
stain from the prosecution of his experiments with Thuja." In the short period of
this trial, there was neither an objective production of the Thuja-sicknees nor were
the subjects of it mortally poisoned. — Mayrhofer.
EffecU of Thuja on the Nervous System. 109
action of Thuja in anatomico-physiological order, in order to assist the
memory as much as possible.
Nervous System. — The, nerves, as the organs for communicating the
sensations, are first of all affected by the disturbing forces of drugs, and
it is through them that the enormous train of subjective symptoms,
manifesting themselves by the different kinds of pains, is developed. Here
lies the reason why the nervous symptoms of many drugs frequently so
much resemble each other ; and on this account it is that they have, as
a general rule, but little therapeutic value.
It is only when such manifestations take place in the track of parti-
cular nerves and locate themselves in the parts supplied by them, and
when there is something peculiar in the mode of their development,
that they have any practical import or therapeutic utility.
The operation of Thuja upon the sensory functions of the cerebro-
spinal system, is evidenced by the following symptoms : flying stitches
through the brain, vertigo, drawing, sticking or boring, screwing, dull,
stunning headache, drawing, tearing, sticking in the head, frontal emi-
nences and zygomata, &c. As special nervous affections of the head,
we have : the feeling as though a convex button were pressed upon the
head, especially in the neighborhood of the sutures, or a needle or a nail
repeatedly thrust in ; hemicrania in the forehead, the pains extending
by radiation into the brain. Belonging to the spinal marrow : drawing,
tensive, sticking, tearing, creeping, xching, burning, laming, digging,
boring pains in the nape, bach', sacral region, nates and limbs.
Nor are the motor nerves unaffected by Thuja, as is plain from the
frequently recurring, involuntary muscular twitchings. In the ganglionic
system the plexus coehacus and hyp>ogastricus were the most affected,
its appears from the abdominal symptoms of the drug.
Wc shall treat more fully of all these subjective or nervous symptoms
when we come to speak of the particular organs affected.
Sleep and Dreaming. — Under this head, Thuja, like almost every
other drug, gives rise to alternate effects; sleeplessness, sleep coming on
late, lasting but a little while, restless, and interrupted by dreams;
groaning m sleep ; unrefreshing dozing with constant terror ; uneasy,
tormenting, horrible images in dreams, e. g. of the dead ; voluptuous,
lascivious dreams ; quiet, refreshing, deep sleep, <fec.
Therapeutic indications cannot bo obtained from the symptoms of
sleep and dreaming alone, as they are not independent pathological con-
ditions, but only the reflex of organic affections. Thus, sleeplessness,
unrefreshing dozing, or restless sleep with dreams, are true accompani-
ments of fever ; tormenting and horrible dreams, with sudden starting
and terror, of cerebral and pectoral affections ; and lascivious dreams,
•mding with pollutions, point to .'in excessive action of the genital
system.
The symptoms afforded by the sleep under the action of Thuja, ac-
cording to their physiological value, are, for the most part, simply
signs of febrile actiou ; they frequently indicate the action of the drug
110 Thuja Ocoidentalis.
upon the genital system, but seldom poiut to any irritation in the cere-
bral organs.
Mind and temper. — Thuja exhibits no marked psychical relations.
With some of the provers there was little or no disturbance in these func-
tions, and the symptoms that were perceived are again only opposite
alternations,* which divide themselves into exaltations and depressions.
The exaltations manifest themselves but seldom ; Ave have disposi-
tion to be angry, inclination for intellectual labor, great activity of the
mind (with weakness of the body) ; the depressions, however, are nu-
merous ; as, melancholy ; discouragement ; anxiety ; restlessness and
lowness of spirits ; ill-humor and disgust of life ; difficulty in recollecting ;
difficulty in finding the proper words ; slow speech, &c.
From these considerations we must draw the conclusion, that the prin-
cipal action of the arbor vita? upon the mind and temper is of a depress-
ing sort, and that the signs of the shackled soul are the indications
that ought to guide us in our selection of it as a remedy.
PERCEIVING FACULTIES.
Visual Organs. — The symptoms which attest the effects of the arbor
vitse upon the organs of sight may be divided into four classes.
1. Subjective: as, sensation as if the eyes toere pressed forward out
of the head, or as though the eyelids were swollen ; drawing, pressing,
sticking or burning in the eyes ; biting, burning in the eyelids, canthi
and caruncles ; feeling of dryness in the eyes, tension in the interior of
the orbits ; digging pain in the posterior part of the eyeball, &c.
2. Objective : redness and inflammation of the white of the eye
(with pressing and biting) ; dilatation and contraction of the pupils (al-
ternate effects) ; watering of the eyes (especially in the open air) ; ob-
struction of the eyes with gum ; swelling of the upper lids ; twitching
of the eyelids ; digging twitching in the eyeball, &c.
3. Symptoms of functional disturbance : short-sightedness ; dimness
of the sight ; obscuration of the sight as though there were a veil before
the eyes : weak sight ; swimming of surrounding objects before the eyes
(Wz.) ; black, self-moving points before the eyes, whether open or shut ;
glittering before the eyes, with hovering of numerous dark and bright
points before them (Zl.) ; appearance of a bright disk with a dark centre
which follows the movements of the eyes (Dr. Huber) ; hovering of
clouds and streaks before the eyes (Lackner).
* The opposite symptoms developed in the psychical sphere by the action of many
drugs, depend upon the universal law of dynamic oscillation, and are (and it is the
same in health) but striking repetitions of the constant pendulum-swing of psychical
life ; from sorrow to joy, from grave to gay, from tears to smiles, from hope to fear,
from love to hate, from pleasure to pain. But as through all the varying tints of the
psychical life of the individual, the temperament and temper, as a sort of ground
color still predominate, these exaltations and depressions, viewed as a whole present
a striking picture, and one which is of the highest import as a therapeutic' indica-
tion in cases of mental disturbances. — Mayrhofer.
Effects of Thuja on the Organs of Sense. Ill
4. Exanthematous appearances : red itching eruptions between the
eyebrows ; suppurating tubercles on the borders of the eyelids, on the
eyebrows, or in the neighborhood of the eyes.
The general character of the sickness produced by Thuja lies at the
foundation of the subjective symptoms : suddenly coming and going,
irregularly periodica], aggravated by rest, morning and evening, amelio-
rated in the open air and by movements, especially attacking the left
side.
As the symptoms of the eyes never appear independently, but always
accompanied by consentaneous affections either of the olfactory and
respiratory apparatus, or of the urinary and genital organs, we cannot
admit any direct and immediate relation between Thuja and the organs
of vision.
In pathological conditions of the eyes, therefore, all the concomitant
symptoms are to be considered, and the hints derived from the preced-
ing history of the disease to be weighed, which indicate the choice of
Thuja, and assist us in the decision.
Auditory Organs. — These organs, which, in comparison with the
other perceptive faculties, are much less often affected, do not escape
the action of Thuja.
Subjective symptoms : hammering and tearing in the ear ; violent
tearing in the concha ; penetrating and squeezing in the ear ; pressing,
obstruction, sticking in the auditory canal ; ringing, roaring, and dull
vibrations in the ears ; thrusting stitches in the right side of the throat,
reaching into the ear, with the feeling as though the air pressed through
an opening (Eustachian tube) into the ear on opening and shutting the
mouth ; single, violent stitches in the auditory meatus ; feeling of stop-
page or as if there were water in the car ; creaking in the ear during
empty deglutition, &c.
Objective results : suppurating tubercles ; moist warts (Wachtel) in
the neighborhood of the ears.
The remarks already made in relation to the eyes will equally apply
to the ears. In diseases of these organs, the choice of Thuja must be
determined by the character of the ear symptoms, by the accompanying
affections, and by the history of the case.
Olfactory Organs. — The symptoms of the nose and its vicinity are
again either
1. Subjective : pressure on the root of the nose ; tension in the right
ala ; sensation of dryness in the nose ; drawing between the mouth and
nose ; crawling in the nose ; burning in the nose with sensibility of the
septum ; itching in the nostrils, &c.
2. Objective : frequent sneezing ; repeated epistaxis ; discharge of
blood by blowing ; running catarrh ; catarrh suddenly ceasing and
reluming, sometimes alone, sometimes accompanied with cough and
febrile symptoms, swelling and hardness on the left ala ; hard scabs in
the nose ; itching eruptions or tubercles behind the alae ; vesicles on the
septum ; a red streak from the nose over the forehead, &c.
112 Thuja Occidentalis.
These symptoms too must be judged of in connection with the other
consentaneous affections, and can very seldom by themselves form
therapeutic indications.
Gustatory Organs. — The operation of Thuja upon the organs^ of
taste, to which head we refer all the parts constituting the oral cavity,
is evidenced by a variety of symptoms, which may be divided into sub-
jective, objective, and functional.
1. Drawing, tearing, sticking, twitching toothache on entering a
warm room ; drawing, tearing, sticking in the jaws ; burning on the
lips, on the tongue and palate ; feeling of soreness on the palate and
tongue ; pressing on the velum palati ; rough, scraping feeling on the
tongue and in the throat ; sore feeling on the point of the tongue ; sen-
sitiveness of the gum ; soreness and dryness in the throat : violent pain
in the masseters as though they were wrenched, <fec.
2. White coating upon the tongue ; sore tongue ; burning vesicles
on the tongue ; painful, swollen gums ; inflamed and swollen tonsils ;
sivelling of the, salivary glands ; increased secretion of saliva ; saliva
mixed with blood ; throwing up of a tough, thick mucus ; sore palate ;
burning, red spots ; elevated, itching spots on the lip>s ; quivering of
the lips ; creaking of the under jaw when chewing, <fec.
3. Sweet, sour, metallic-tasting saliva ; sweetish, insipid, sharp, bitter,
rancid, resinous taste ; taste blunted (food cannot be distinguished by
the taste) ; thirstlessness ; thirst ; desire for cold drinks, &c.
The subjective symptoms have but little practical value, inasmuch as
many other remedies develope them in the same way ; the objective,
however, are much more important, and highly valuable in a therapeutic
point of view, especially when they are manifested in connection with
other characteristic symptoms.
SANGUINEOUS SYSTEM.
Fever. — Every medicinal agent in its perfect action excites fever, and
.thus presents differcr.l peculiarities according to the different power of
the drug.
The species of favor which is developed in those who have an exceed-
ing susceptibility to the action of Thuja, or which follows in the train
of massive doses of the drug, either appears unaccompanied or attended
by a catarrhal affection of the olfactory or respiratory organs.
The independent fever, according to the preceding provings, manifests
the following peculiarities :
1. It is a well marked cold fever (febris algida). Its symptoms all
point to a preponderance of the cold stage. The chill commences
generally from the spinal marrow, is especially felt in the limbs, more
particularly in the feet, at times only on one side or only internally, and,
in its highest development, is attended by trembling of the heart, mo-
mentary pulselessness and deadness of the fingers ; it either passes im-
mediately over into the sxecating stage, or alternates several times wit])
Effects of Thuja on the Respiratory Organs. 113
heat ; nay, the extremities are often still cold after the body has become
hot. The hot stage seldom attains much intensity, and is generally first
perceived in the face while the rest of the body is still cold.
2. Regularly, it comes on morning and evening, more seldom in the
course of the day ; thirst is generally altogether absent or comes on
with the hot stage, and is seldom of any account.
The general 'weakness and prostration is so remarkable that it by no
means corresponds to the degree- of the other symptoms.
3. In its course, it shows either a quotidian or tertian type, or an
irregular perodicity. The fever that attends the affections of the mucous
membranes has the peculiar property of being as cajwicious and change-
able as the subjective symptoms of Thuja.
Respirator)/ Organs. — We come now to the phenomena which the
arbor vital excites in the air passages, larynx, trachea and its ramifica-
tions, to which we also add the symptoms of the lungs and pleura.
The very decided action of Thuja upon the mucous membrane of the
nasal and buccal cavities, might have already led us to conclude that it,
would also produce pathological conditions in the lower air passages,
and our provings have accordingly shown that it can especially attack
the thoracic organs (though only exceptionally).
1. Sensitiveness of the larynx ; scraping, sticking in the trachea; dry-
ness and roughness in the fauces ; oppression in the chest ; pressing
immediately under the breast-bone or on one side of the chest ; draw-
ing, tearing, sticking on one side of the chest ; sensation as though the
chest were compressed from without and the corresponding part of the
lungs from within ; internal sensation of soreness in the chest ; pressing
in the lower half of the chest ; stitches in the left side of the chest, un-
affected by inspiration and expiration ; dull, interrupted stitches in the
chest ; violent sticking in the lower part of the lungs, which is aggra-
vated by sneezing, deep breathing and coughing, &c.
2. Hoarseness ; short, dry, straining, interrupted cough; troublesome
night-cough ; raising of thick, tough mucus,, like lard ; short, con-
stricted, accelerated respiration ; moaning and groaning in sleep.
We by no means mean to deny that Thuja possesses the power of
affecting the respiratory organs, nor that it can excite in them a con-
gestive or an irritative condition, but we must regard the affections of
the lungs and pleura which follow its exhibition as individual exceptions
and statistical singularities which are no essential attribute of its opera-
tion ; in this respect we need only mention Aconite, Bryonia, Rhus,
Tart. Emct., to show that it is far surpassed by many other remedies.
On this account we can allow to the chest-symptoms of Thuja but a
low and conditional therapeutical value.*
* I cannot entirely coincide in this opinion. The author points out that Thuja
acts first and most especially upon the uro-genital organs. The intimate physio-
logical and pathological relation between these and the respiratory organs would
have made it very probable a priori that the latter would be partakers of the effects
of Thuja. In effect, not only our own but Hahnemann's experiments show that
I
114 Thuja Occidentalis.
Heart, Vessels, and Muscles. — The few symptoms of the heart pro-
duced by Thuja, such as palpitation, trembling of the heart, transitory
pulselessness, pressure in the scrobiculus with difficult respiration, unea-
siness and anxiety (anxietas prcecordialis), are the attendants of fever,
particularly of the cold stage. They point to a repletion of the central
organ with blood, and to an impeded circulation. They do not appear,
therefore, as direct effects of Thuja upon the heart, and have no special
therapeutic value.
Besides the changes in the pulse, the maximum and minimum of
which were observed to be over one hundred and under sixty in the
minute, there are other symptoms which indicate the action of Thuja
upon the venous system ; as, swelling of the veins in the neck, temples
and hands ; turgescence of the hemorrhoidal vessels ; burning in the
varices ; pressing in the hypochondria.
A peculiar symptom of frequent recurrence is the twitching or jump-
ing of isolated muscular parts in the legs, calves, toes, arms, hands, and
fingers, more seldom in the trunk ; also on the lips and chin. This
symptom appears in a lower degree as a subcutaneous vibration or slight
trembling of parts of muscles. The twitching is especially perceived in
the middle, in the body of the muscles, appears almost exclusively
during rest, in short, repeated attacks, and rapidly disappears on move-
ment ; a sudden twitching of the upper part of the body or of the feet
comes on more violently.
We attach therapeutic value to the muscular twitchings of Thuja.
REPRODUCTIVE SYSTEM.
Digestive Organs. — All remedies when taken in sufficient quantity
excite morbid affections in the primaa vise with which they are first
brought in contact ; and even those which in themselves are innocuous
may become injurious if administered in large doses.
Hence it results that many similar phenomena take place in the di-
gestive organs after the exhibition of different drugs, which has led
our opponents to assert K \ that according to the homoeopathic materia
medica, every drug was good for every disease, and every disease indi-
cated every drug." *
the mucous membrane of the air passages (nose, trachea, and bronchi) plays by no
means so subordinate and accidental a part in the physiology of the arbor vital as
the author would have us believe. In many of the provings, and especially in those
where the uro-genital organs were affected but slightly, or not at all, they form
(according to my view) the starting point for a great part of the symptoms detailed.
This was the case with Gross, Biihm, Laclcner, Landesmann, Liedbeck, Reissin-
ger, Sterz, and Wurmb ; nay, with some of them, for example, with Maschauer.
.._.• symp-
toms. — Ed. Oest. Zeit.
* This maxim applies perfectly per irwersionem to the therapeutics of the old
school : for a casuistic materia mediea can with perfect propriety administer every
remedy in every disease, or treat each disease with all remedies. — Mayrhofer.
Effects of Thuja on the Digestive Organs. 115
Tho symptoms of the organs of deglutition are : scraping feeling in
the pharynx and throat ; pressing when swallowing ; feeling of con-
striction of the pharynx; accumulation of mucus in the throat and
pharynx.
Stomach : eructations tasting of the drug ; nausea ; vomiturition ; infla-
tion of the stomach with flatulence ; pressing and griping in the region
of the stomach ; heartburn ; cramp.
Bowels: rumbling and rolling, griping and cutting, with inflation of
the abdomen ; colicky pains ; deceptive feeling as though something
alive were moving in the abdomen ;* flatulence.
The symptoms which indicate an affection of the liver or of its peri-
toneal envelope, are : pressing in the liver as if from a stone ; sticking
in the abdomen, rendering walking difficult, &c.
Stool : ineffectual urgency ; diminished evacuation ; constipation for
several days ; as an alternative effect, not of frequent occurrence, loose
papescent stool or even diarrhoea ; while at stool, sticking pain in the
rectum ; after stool, burning and itching in the anus ; biting, itching,
and burning at the anus and in the sulcus without stool ; swelling of
the hemorrhoidal vessels ; feeling of swelling at the anus ; a less fre-
quent alternative effect, feeling of emptiness there ; moisture of the
anus ; sweat on the anus ; excretion of bloody slime from the anus, &c.
The groups of the symptoms of Thuja affecting the anus and rectum
are of importance in a therapeutic point of view, because the symptoms
exist abundantly in the provings, come on regularly after every dose,
and are an integral part of the peculiar condition which that drug ex-
cites in the urinary and sexual organs, in connection with which they
must be regarded and judged.
Urinary and Sexual Organs. — We come now to the organs toward
which Thuja stands in the most intimate relation ; the uro-genital appa-
ratus and its connections.
(a) Urinary Organs. — In order to aid the memory we again divide
the phenomena into subjective and objective. .
In the first class we have : burning in the renal region ; drawing
along the ureter to the bladder ; sensation of inflation and ful-
ness in the vesica with urgency to urinate ; frequent urgency to urin-
ate ; pressure on the neck of the bladder ; painful stitches from the
anus to the orifice of the urethra or in the reverse direction ; stitches in
the fossa navicularis ; voluptuous itching or tickling in the urethra ;
cutting in the region of the cervix vesicce during urination and at other
times ; burning toward the bulbus of the urethra ; burning in the ure-
thra and at the orifice during, after, and without urination ; itching
on the point of the urethra ; itching without and also during urination
through the whole urethra ; drawing and cutting in the urethra and
vesica ; deceptive sensation as if a tenacious fluid were passing forward
* The sensation as though something alive were moving in the abdomen seems
to arise from the stretching of the intestines by the accumulated flatulence.
Mayrhofer.
116 Thuja Occidentalis.
in the urethra, or as if there iu?e still some drops of urine left after
urination, d'c.
To the second class belong : frequent, copious emissions of limpid,
straw-yellow urine ; at times interrupted urine ; scanty discharge of
dark urine with inflammatory irritation of the urinary organs ; red sedi-
ment in the urine ; discharge of glutinous mucus from the male ure-
thra ; discharge of liquor prostaticus (Hempel) ; mucous discharge
from the female urethra, <&c.
To these phenomena in the urinary apparatus, correspond the symp-
toms of the
Sexual Organs. 1. Subjective symptoms.
(a) In the male organs : sticking and itching in the glans : single,
flying stitches on the point of the glans ; burning itching, sensation of
soreness on the glans ; great sensibility of the whole glans ; painful
stitches on the inner surface of the prepuce ; tickling, itching, and
biting on the glans and prepuce, alternating with flying stitches in the
anus ; twitching pain in the penis ; burning stitches in the penis as far
as the testicles ; drawing, sticking in the testicles and seminal cords ;
crawling and itching on the hairy parts of the genital parts and the
inner side of the thigh ; sticking in the perinccum ; tension and drawing
in the groins.
(b) In the female organs : pressing and constriction of the genital
parts ; tight pain in the genital parts and perimeum ; pain as if sore ;
itching in the pudenda ; biting and burning in the vagina ; sticking
in the groins (extending through the thigh into the knee).
2. Objective symptoms.
(a) In the male organs : swelling of the prepuce ; red spots on the
glans and prepuce ; erosions on the inner surface of the prejiucc and on
the furrow of the glans, which become moist and purulent; a red ex-
crescence on the inner surface of the prepuce (like a condyloma) ; a gra-
nular, elevated spot on the external surface of the prepuce which sup-
purates, forms a scab, itches and burns ; small elevations on the corona
glandis, smooth, red excrescences on the point of attachment of the
prepuce ; on the glans; a fat, foul, burning ulcer with a red margin
on the corona glandis ; moistening of the glans ; gonorrhoea of the
glans ; moist erujrtions on the scrotum ; profuse sweat of the genitals
and perinccum ; retraction of the testicles toioard the inguinal ring ;
puffing and projection of the perinceal raphe ; sup>purating tubercles on
the perinceum ; swelling of the inguinal glands, &c.
(b) In the female orgcins : swelling of both labia ; leucorrhcea from
one period to another, mild, and leaving greenish yellow spots on the
linen.
3. Functional symptoms.
(a) In men, pointing to an excitement of the sexual system : exces-
sive sexual impulse ; frequent erections ; pollutions ; seminal emission
with sensation as if the urethra were too narrow : indicating a lowering
Effects of Thuja on the Genital Organs. 117
of the sexual impulse; indifference to the other s£x ; unfrequent desire
for coition ; inability to perfect copulation.
(b) In females : retardation and diminution of the catamenia.
This formidable host of subjective and objective phenomena, to which
Thuja gives rise in the uro-genital system, leaves us no room to doubt
that it stands in a near and direct relation to these organs, and lu this
sense is a urinary and genital remedy.
As however the determination of the therapeutic utility of the re-
corded results of the provings depends upon the frequency and con-
stancy of their occurrence, as Avell as upon thejr agreement with the phe-
nomena of natural diseases, we must subject these numerous symptoms
to a scientific arrangement, in order to trace the conditions which indi-
cate the choice of Thuja as a remedy.
The ruling kind of pain produced by Thuja in the urinary organs is
burning. Its seat for the most part is the fossa navicularis, less fre-
quently the orifice of the urethra, less frequently the region of the pros-
tate gland and cervix vesical, and seldomest of all the ureters and kid-
neys. It is manifested especially during and after urinating, and with-
out that is often replaced by voluptuous itching. The urine <" n ~ Tally
runs freely without any delay, but urgency to urinate soon c les on ;
the stream is seldom interrupted by cramp. By this meatus Thuja is
distinguished from its closely allied drugs, Cantharides, Sabina. Can-
nabis, Petroselinum, and others which hinder the urine more or less.
The feeling as if some drops were still running forward in the urethra
is frequently developed after urination. In quality the urine remains
about the same, in quantity it is almost always increased.
There is no special violence in the irritative condition which Thuja
induces in the urinary organs, as is evident from the fact that the mu-
cous flow from the urethra (as an inflammatory product) is mostly
wanting or is very slight ; in which respect it is far inferior to other
remedies, for example hemp. On the other hand, Thuja more fre-
quently excites inflammation and blennorrhea of the glans than other
remedies.
In relation to the sexual functions, we find alternating effects, point-
ing now to excitement and now to depression of the sexual appetite.
On taking a general view, however, of all the provings, it becomes evi-
dent that the diminution of the sexual impulse is the more constant,
and therefore the reliable therapeutic effect ; and this is especially corro-
borated by the deficient catamenia which Thuja occasions, for deficiency
of the menses and weakness of the sexual impulse are as constant com-
panions as excessive menstruation and increased venereal desire.
In this relation, Thuja is connected with Cannabis, and stands di-
rectly opposed to Sabina, which causes excitement in the sexual system,
especially in the female.
The most important peculiarity of Thuja then, is excitement of the
cutaneous system of the sexual parts and their neighborhood.
Genital sweat, balanorrhcca, suppurating tubercles, swellings and ex-
118 Thuja Occidentalis.
crescenccs on the skin, which must be regarded partly as crises, are
speaking evidences of this tendency ; and in this property Thuja yields
to no other remedy.
The symptoms of the testicles and inguinal glands are consensual
effects.
We have also the following characteristic marks of the operation of
Thuja on the uro-genital system : burning and itching in the urethra,
especially in the fossa navicularis, urgency to urinate, with increased,
uninterrupted urine, slight thickish mucous discharge from the urethra,
balanorrhaa, cutaneous excrescences, diminution of the catamenia and
of the sexual impulse, moderate leucorrhcea.
Glandular System. — Copious symptoms testify the action of Thuja
upon this portion of the organism.
The cervical and salivary glands, the inguinal, and those of the pre-
puce, swell and become painful ; the salivary and sebaceous glands
are excited to increased secretion. Irritation lies at the basis of all these
symptoms. When we reflect upon the general effect of Thuja upon the
totality of the cutaneous surfaces, we could scarcely expect that the glands
which stand in organic and vital relations with them should escape its
action ; though we must regard the glandular affections produced by it
rather as sympathetic than idiopathic.
Skin. — The physiological provings of Thuja have shown that it ma-
nifests its action by means of eruptions and excrescences on the cuta-
neous surface. We have already had occasion, when considering the
symptomatology of the senses and genital system, to remark this pecu-
liarity, and it now remains to submit to a closer examination the cuta-
neous symptoms which Thuja produces upon the trunk and limbs.
1. Subjective: crawling, itching, biting, burning, pricking and stick-
ing in different spots on the skin ; occasionally gurgling and running
under the skin, as from single dribbling drops of blood. The most con-
stant and most frequent kind of pain produced by Thuja upon the skin
is itching, and in a higher degree, burning :
2. Objective. These are partly inflammations, partly eruptions, partly
excrescences, which have been observed under the following forms :
(a) Red smooth spots (maculae) which appeared singly, or several at
a time, for the most part upon the limbs (those upon the prepuce, glans
and lips, were spoken of under these organs) ; which itch, burn after
being scratched, and in a few hours or during the night disappear as
quickly as they come.
(b) Burning vesicles (papulae) which were only noticed upon the
mucous membrane of the tongue, on the palate and glans.
(c) Moist and suppurating erosions, which likewise appeared only
on the mucous membrane, glans, and prepuce.
(d) Tubercles (nodi), of different sizes, which appeared sometimes
several together, as on the scalp, sometimes single, in the neighborhood
of the parts of generation, on the limbs, on the face, <fec, commonly
surrounded by a reddish or brownish base, itching and rapidly passing
Effects of Thuja on the Membranes. 119
into suppuration on the summit ; the smaller appeared like an eruption,
the larger resembled chicken pox (varicellae).
(e) Warts (verrucae), which assumed various shapes ; either as smalt
red excrescences on the genitals, or as the common dry warts on the
hands, which are either conical or roundish ; in their commencement
show a smooth surface, but in the course of their growth become
cracked, and resemble mulberries ; or as moist, sweating excrescences,
which were observed at the anus, on the perinceum, in the furrow be-
tween the nates, and on one ear. As indications of cutaneous excres-
cences, fulness of the perineal raphe and of the anus are to be remarked.
These cutaneous symptoms all appeared after a longer use of the
Thuja, and on that account we must set them down as among its secon-
dary effects.
The notable peculiarities of Thuja-warts and tubercles are :
1. Their broad conical shape.
2. Their situation in the superficial cutaneous tissues.
3. The splitting and cracking of the superficies in the larger and
older warts.
4. The disposition to suppurate or to be moist, especially in the warty
tubercles which make their appearance in the neighborhood of the
sexual parts.
5. Their chronic course, which with warts may last many weeks and
months.
Fibro-serous membranes. — Under this head belong most of those
symptoms which we have noticed as Thuja pains under the nervous
system, and which have their seat in the muscular sheaths, in the apo-
neurotic expansions, perhaps even in the muscular tissue itself, and
which resemble wandering rheumatic affections. "We have already
noticed the symptoms of the mucous membranes under the separate
organs.
Osseous System. — The symptoms which indicate the operation of '"
Thuja upon the osseous system or periosteum are but few. The gnaw-
ing and boring pain which is characteristic of affections of the bones,
seldom appears in the provings. But a sure indication of a periosteal
affection is the frequent, painful feeling in the articular extremities of
the hollow bones, aggravated by movement, and frequently accompanied
by swelling of the painful spot.
General. — The following general characteristics of the Thuja-sickness
we derive from the statistics of the provings, and from the discussion of
the symptomatology of the arbor vita; : they are identical with the
general therapeutic indications.
1. Thuja enjoys a very extended circle of operations ; almost every
system, province, and organ of the whole body is more or less affected
by it ; but it stands in the most intimate relation :
(a) To the uro-genital system ; and
(b) To the cutaneous system in all its ramifications.
In this relation, the arbor vitre is a urinary, sexual, and cutaneous
120 Thuja Occidentalis.
remedy. In the urogenital system, the urinary apparatus is idio-
pathically affected, the sexual organs sympathetically .
Of the cutaneous tissues, the fibro-serous and mucous membranes
bear the stamp of primary effects ; the external skin, of the secondary.
2. The general character of the pathological condition, which Thuja
sets up in the attacked parts, is that of irritation.
This irritation, which may even increase to inflammation, causes in
th secreting organs (mucous membranes, urinary apparatus and glands)
an increased and altered secretion. In the external skin the irritation
is concentrated in single spots, and manifests : inflammation, suppura-
tion, formation of warts, and excrescences.
3. The affections of Thuja present the following peculiarities :
(a) They attack only a single organ, limb, joint, or spot at a time ;
and these local affections usually cease when morbid symptoms arise in
a different province.
(b) They come on for the most part in ubrujjt paroxysms, begin sud-
denly, and end as though they were snapped off.
(c) They make their appearanee especially during rest, and either
diminish or disappear by movement ; nay, the pains which appear in
circumscribed spots often instantaneously disappear on touching the
d spot, and return immediately on quitting the contact. They
come on consequently for the most part in the evening in bed, and in the
morning on waking; they are aggravated, too, by jessing from a cold
into a warm temperature, and are diminished by the opposite. The
pains in the joints only are aggravated by movement, and violent affec-
tions or febrile symptoms remain the same whether in rest or motion.
(d) They more frequently affect the left side of the body, though they
do not on that account neglect the right.
4. The most constant kinds of pain which Thuja excites in its most
extensive sphere of operation in the different organic structures, are :
drawing and tension in the limbs and joints, burning in the urinary
organs, itching and crawling on the skin.
5. The course of the Thuja-sickness is partly acute, 'partly chronic.
The symptoms of the primes viae go off in a short time, but those of
the sccunda; vice run a very irregular course, and are characterised by
great mutability and caprice. They return after intervals of hours,
days, weeks, continue sometimes shorter and sometimes longer, and
appear now in this and now in that part of the body. The cutaneous
excrescences finally, as the concluding products of Thuja, are as slow in
disappearing as they are in coming, and remain for months.
6. The true attendants of a Thuja-fever are strongly marked, predo-
minant cold, and gloomy, depressed, state of mind.
To express the physiological character of the arbor vita: in the
shortest manner, it is, '■'■Exaltation of the cutaneous system, with dispo-
sition to dermatic excrescences?
Therapeutics of Thuja. 121
CHAPTER VI.
T/ierapeutics of Thuja.
Physiological drug-provings are so many questions propounded to the
living organism ; the pathogenetic phenomena thereby developed are
the answers returned, and also the material for the foundation of thera-
peutics ; and the accuracy of the therapeutics is determined by the usus
in morbis.
By the physiological proving of a remedy health is interrogated con-
cerning disease ; by the pathological proving sickness is interrogated
concerning health ; and from the agreeing answers of these two trials
of nature results as a whole the science of pharmacodynamics.
By the physiological method, the powers of the drug are discovered ;
by the pathological, its therapeutic powers are confirmed ; these two in-
separable parts are related to each other as flower and fruit, as assertion
and proof ; and confirmed therapeutic indications are the highest flower
and fruit of the physio-pathological materia medica. The physiology
of a drug without the therapeutics is dead knowledge ; its therapeutics
without its physiology is blind opinion ; sure knowledge is only reached
when we obtain the physio-pathology of a remedy blended into one by
means of a great general therapeutic principle.
The general therapeutic indications which we have developed by the
characteristics of Thuja, have their significance in all the disorders that
come under its province; and the particular indications are derived from
the physiological effects of the remedy upon the separate systems, pro-
vinces and organs.
Before we consider more intimately, and illustrate by cases, the the-
rapeutic indications of the arbor vitce (which are identical with its
characteristics) in connection with those special forms of diseases which
lead us to its employment, let us for a moment look at the indications
laid down by Hahnemann ; he expresses himself thus :
" The homoeopathic physician will know how to value the clearly
observed artificial elements of disease produced by this uncommonly
powerful drug as a great addition to our previous stock of remedies, and
will not neglect to make therapeutic use of it in some of the most
serious diseases of man, for which, until now, no remedy had been dis-
covered. It will appear, for example, from these symptoms that Thuja
is a specific for that horrible affection arising from impure cohabitation,
condylomata, when it is complicated with no other miasm, and. expe-
rience shows that it is the only useful remedy for it ; it also for the same
reason most certainly cures that severe form of gonorrhoea arising from
impure connection, provided always it be not complicated with any other
miasm."— {Rein. Arz. 2 Aufl. B. 5. s. 122.)
With how much justice Hahnemann decided upon the remedial
122 Thuja Oecidentalis.
power of Thuja from its proving?, let the cures performed by it testify ;
for blennorrhceas of the sexual organs which have arisen from contagion,
and the sycotic condition that so frequently attends them, are especially
the therapeutic field in which the arbor vita; has gained its most
plenteous as well as its most beautiful laurels.
A.
Diseases of the Urinary and Sexual Organs.
(a) Blennorrheas. — The condition which Thuja excites in the urinary
organs, is characterised as irritation of the mucous membrane, with in-
creased and altered secretion.
The special therapeutic indications which insure the selection of Thuja
are : contagion from coitus ; burning, itching pain in the urethra, gene-
rally when urinating, and immediately after, less often without this cause,
and which is seated in the fossa naviculars or near the cervix vesicae ;
increased, but little altered urine ; purulent mucous discharge from the
urethra or glans, from the urethra or vagina, sensibility of the glans
and penis ; swelling of the inguinal glands ; tendency to chronicity and
to lympathic vascular excrescences.
Hahnemann states that Thuja is indicated by the following symptoms
(Chron. Kranlc. B. 1) : "Thicldsh, purulent discharge from the com-
mencement, urination little painful, body of the penis somewhat hard
and swollen, or painful on the dorsum and beset with enlarged glands."
This agrees with our physiological therapeutic indications.
1. A gonorrhoea of six weeks standing had already been treated with
cubebs, camphor, tinctura kalina, and aqua laurocerasi, and had for a
short time been subdued. The discharge was copious, rather yellow than
white, the urinary secretion natural, tickling in the urethra when urinating,
at times cutting in the groin.
Two doses of Cann. 2 (one drop), which Dr. Hartlaub administered, with
an interval of eight days, produced no impression.
On taking Thuja 30 (ten pellets) the discharge became less and white
and the pains disappeared. As however some cutting on urination was
still perceived at the end of seventeen days the patient again took Thuja 30
(five pellets). The discharge at the end of three weeks was white, and
only amounted to a couple of drops a day. Hartlaub again administered
Thuja (in what dose is not mentioned), and ten days later, when 'the noc-
turnal erections were somewhat painful and the discharge continued, but in
a less degree, Capsic. 9 (ten pellets). After fourteen days the patient was
well and had no relapse.* — (Annalen der homceop. Klinik. B. 3, s. 214, 215).
The second case of gonorrhoea cured with Thuja by Hartlaub is as
follows.
2. A strong young man who had often had gonorrhoea, had suffered from it
now for five weeks and had already taken much cubebs. The disease had
* " Perhaps," adds Hartlaub, " I might have saved Thuja, had I waited longer."
We rather think that this cure of seventy-eight days might have been somewhat
shortened by more frequent doses of Thuja. — Mayrhofer.
Cases of Gonorrhoea. 123
come on from the commencement with great pain and hematuria. The dis-
charge was still very copious and watery, urine natural. When urinating,
he felt violent burning, now in the anterior, now in the posterior part of the
urethra, the inguinal glands were swollen and somewhat painful.
All these troublesome symptoms disappeared within eighteen days after
a dose of Thuja 30 (five pellets), and there only remained a very moderate
discharge, which so far disappeared after two similar doses, a fortnight
apart, that the urethra was only slightly obstructed on waking in the morn-
ing. One dose Cann. 6 (one drop) caused this also to vanish within a short
period.*
3. A man of scrofulous constitution, age 24, contracted a gonorrhoea after
a suspicious coitus, and according to his story it first appeared fourteen days
afterwards. Before he applied to Dr. Hartlaub he had consulted a quack,
and received from him an almond emulsion with camphor, which he had
taken for several days. At first he had only discharge from the urethra
without any pain ; after using the camphor, however, the dischrrge in-
creased and the pains appeared.
Discharge greenish-yellow. When urinating he felt violent burning in
the glans, which remained sometime after. When not urinating he had fre-
quently during the day itching pain along the whole urethra, and continual
itching on the glans. At night he was driven out of bed by painful erec-
tions. Urine reddish, with whitish sediment, bowels sluggish, the right in-
guinal gland swollen and painful. After the bowels had been regulated by
a dose of Nux Vom., no other change in the disease supervening, he took,
three days after, Thuja 20. In five days the itching on the glans and the
painful erections had altogether disappeared; the burning on urination and
the gonorrhoea were less, the urine was clearer, but still deposited a sedi-
ment. Seven days after the improvement ceased, and for a hasty urgency
to urinate, which often appeared, especially when standing still after moving,
a dose of Puis. 12 was given; in two days after the urgency to urinate dis-
appeared, as did the painful swelling of the inguinal glands, the discharge
and burning on urinating were still less, and this last changed into a slight
sticking and cutting in the glans. For these symptoms Hartlaub, after a
fortnight, gave Cann. 2. The pains ceased, but the discharge was un-
changed, and was only wholly cured after a second dose of Thuja.f — An-
nal. der homccop. Klinik. B. 1. s. 188, 189.
4. Dr. Argenti relates the following case (Archiv fur homoeop.
milk. B. 18. H. 3. s. 84) :
A. D., twenty-four years old, contracted a venereal gonorrhoea. He was
advised to take Balsam Copaiba, the more the better; which he faithfully
did. After some days violent pressing pains in the testicle and spermatic
cord (it is not said of which side) came on, with hard swelling of the tes-
ticle, and his nights were sleepless through the pains. After two doses a
day of Pulsatilla,], the trouble in the testicle disappeared after four days,
* Hartlaub observes that Cannabis is more useful in acute and Thuja in chronic
gonorrhoea, which, if taken cum grano salis, agrees with our own experience. —
Mayrhofer.
t We think that Thuja was the homceopathically indicated remedy in this case,
and are of the opinion that a few doses of that drug alone would have sufficed to
remove the disease. — Mayrhofer.
$Thc size of the dose is nowhere mentioned in the history of this case. —
Mayrhofer.
124 Thw/a Occidentals .
but in a few days returned, without any perceptible cause, in all its violence,
Puis, was now of no service, the pains became still more severe ; but Ar-
nica, taken four times in two days, cured the disorder in the testicle entirely
and permanently. The gonorrhoea was first removed by Thuja after a fort-
night.*
(b.) Diseases of the Prostate Gland.
The affections of the prostate are so often a stumbling block in the
way both of the patient and the physician, that we must receive with
gratitude a remedy which promises to be useful in lesions of that organ
with gonorrhoea.
Our provings have plainly indicated affections of the urethra in its
prostatic portion, and if no decided disease of the gland was developed,
still we may, at least, infer that that organ was not entirely unaffected.
Perhaps experiments of longer duration might develop clearer results
than pains in the neck of the bladder and discharge of prostatic fluid
(Hcmpcl), if they were carried so far as seriously to endanger the
health.
We must content ourselves, therefore, with directing the attention of
our readers to the fact that Thuja, which corresponds to the chronic and
irregular course of a gonorrhoea, may also prove serviceable in lesions
of the prostate gland — (See Editor's note, ante).
Unfortunately our homoeopathic literature, thus far, contains but few
communications on the treatment of the prostate.
Dr. Attomyr (Archiv fur horn. Hcilk. B. 18, H. 3. s. 46) states
* Will these four cases stand the test of critical investigation as scientific cures ? I
doubt it much. The remedial power of Thuja in common (primary, acute, inde-
pendent) urethral gonorrhoeas, is, according to my experience, exceedingly proble-
matical. And our physiological provings give us a sufficient explanation on this
subject. This remedy should be more serviceable in gonorrhoea of the glans and
prepuce. It affords us, however, certain aid in those secondary (consecutive) sym-
pathetic, chronic, gonorrhaeal discharges which, as Hahnemann teaches, are derived
from (what according to Ricord's able researches is still somewhat apocryphal)
condylomatous contagion (a), are accompanied by condylomata (Ricord's mucous
tubercles) ; or which, as Mayrhofer correctly points out (b), are followed by a lesion
of the prostate gland (irritation, congestion, inflammation), or, on the other hand,
have been excited and maintained by such a lesion. In relation to this last, my
learned friend Dr. Bohm informs me, that an extensive experience has taught him
that we can count with probability upon a sympathetic affection of the prostate, in
all gonorrhoeas of regular course, in individuals of a good constitution, which have
lasted longer than six or eight weeks, and that the cause of a good half of all chro-
nic gonorrhoeas may be sought either in simple hypertrophy, in hyperaemia or infil-
tration of the prostate, especially of its middle lobe and excretory ducts. It is in
such cases as these that Thuja proves especially useful, nay, surpasses every other
remedy. He can produce more than twenty cases from his own practice, which,
though of long standing, and treated with the most varied remedies, have yet
yielded immediately and perfectly to Thuja alone. Nay, so firm is his conviction
of the remedial power of this drug upon the prostate, that, he administers it even
in suppurations of the gland, and when he has not effected a cure he has often by
its means obtained a considerable mitigation of the urinary troubles. — Ed. Oester.
Zeit.
Condylomata. 125
that he has employed Thuja in gonorrhoeas with predominant prostatic
affection, and has been well satisfied with the result so far as the pro-
state was concerned. He thus cured in six weeks a considerable and
very painful affection of the prostate induced by bad conduct during a
gonorrhoea, in the course of which the once corpulent patient had become
greatly reduced.
Dr. Hartlaub rapidly cured a painful sensibility when urinating, the
remains of a prostatic inflammation, by a single dose of Thuja 18. The
patient, a young man, suffered from chronic gonorrhoea. The inflam-
mation itself had been cured by Pv.h.— (Prakt. Mit. <£c. 1837-38.)
(c.) Condylomata.
The power of Thuja to produce, besides gonorrhceal affections, cuta-
neous excrescences on the parts of generation and on other parts of the
body, in the form of tubercles and warts, as secondary products, induced
Hahnemann to regard it as a specific against the condylomata so fre-
quently attending gonorrhoea. It has also been considered as a power-
ful remedy in obstinate sycosis, not only by homoeopathic physicians,
but frequently by those of the old school, sometimes secretly, some-
times openly, but ever without mention of the source from which they
derive it.
The special therapeutic indications which point to the employment of
Thuja in sycosis, according to the result of the physiological provings
and of clinical experience, are the following : gonorrhoea, past or still
present, or leucorrhcea, condylomata on a broad base, cracked, mulberry-
shaped moist surface, itching and burning in the excrescences, alternate
amelioration and aggravation of the affection.
To these positive indications we may add one of a negative character,
namely, that mercurial preparations'" or caustic, occasionally used against
condylomata, remain ineffectual, by which latter means they are driven
from their original seat and make their appearance on unusual parts of
the body.
Dr. Trinks has written a short treatise on sycosis and its cure (An-
nalcn dcr horn. Klinik. B. 1. § 185).
" This (miasmatic) disease is quite frequent in Dresden, and I have had
occasion to observe it in various complications and extent. Like-syphilis, it
commonly first appears upon those parts that have received the contagion ;
in man, upon the glans, the folds of the prepuce, the orifice, of the urethra ;
in the other sex, on the labia minora and majora, on the clitoris, &c. If no
impediment is put in the way of their growth, they very soon notab'y in-
crease in circumference and in number upon the original spot; if, on the
other hand, they are destroyed by external applications, caustic, amputa-
tions, &e.) the disease disappears from that place in order to break out
* Condylomata attendant upon chancres disappeav under the use of mercury ;
those which accompany gonorrhoea do not diminish under that remedy. — Lou-
vrier's Syphilidologie.
126 Thuja Occidentalis.
afresh in another. It then appears in the neighborhood of the anus,* in the
axilla:, in the fauces, on the lips, the external surface of the iris ; and in
women, on the nipple."f
" Their form is likewise various. I have seen them on the penis in the
form of many-pointed warts, of cockscombs or cauliflowers, and the same in
the fauces. They rest upon a broad base on the lips and breast, on the
anus and in the furrow. As to their consistence they are generally soft,
seldom hard and horny (when they present the warty appearance). The
soft excrescences for the most part distil a stinking moisture ; they seldom
discharge blood."!
" I have frequently seen this disease uncomplicated, as small wartlike
excrescences upon the glans and prepuce, which gradually increased at the
base ; all that was necessary for a perfect cure was six weeks, and one or
at most two doses of Thuja."
"Condylomata frequently came, too, complicated with gonorrhoea, the
stains of which upon the linen were greenish-yellow, and which was at-
tended with burning pain in the fossa navicularis during and after urination.
For these cases also, Thuja was a specific ; the gonorrhoea commonly dis-
appeared first, then the condylomata."
" More frequently still, I have seen condylomata complicated with primary
syphilis ; with chancres on the glans, on the frenulum and inner surface of
the prepuce, accompanied by simultaneous inflammatory swelling of the
prepuce and inguinal glands."
" The cure of this complication is not difficult, if the patient have not
taken large doses of the mercurial preparations. Where they had not done
so, 'I began the treatment with a small dose of Merc, solub., allowing it to
operate as long as it produced any improvement. In some cases, the sy-
philis was thoroughly eradicated by this dose aloue ; but in the majority, a
second and even a third were necessary. Then I followed quickly with the
arbor vitse. But if mercury had been previously exhibited in large doses
both externally and internally, the difficulty of the cure was much increased.
I was then obliged to give first a dose of Calc. sulph. or Acid. nit. to
destroy the excessive effects of the mercury. During the operation of this
remedy, the two co-existing diseases frequently took onJ.heir original forms."
"Quicksilver given in suitable preparation and dose now completed the
cure of the syphilis, and the sycosis soon followed on the exhibition of its
proper remedy."
" The exhibition of Thuja is often alone sufficient thoroughly to eradicate
* Condylomata frequently affect the anus, perineum and thighs, by natural
growth in extension. — Mayrhofer.
t According to Ricord, who distinguishes the broad condylomata (condylomata
lata, papules muqueuses) from the pointed, pedunculated excrescences (condylo-
mata acuminata) which he calls "Vegetations," these growths may also appear
in the external auditory meatus, on the nose, tongue, cheeks and tonsils, in the
larynx, on the navel and vagina, on the neck of the uterus and between the toes.
— Mayrhofer.
i Condylomata on the nose and commissures of the lips display deep furrows and
tend to scab over. Those on the tongue resemble aphtha;, appear singly or in
small numbers, and look like little gray, granular prominences, which seem to be
covered with false membrane. They frequently return after many years (10 to 15)
and not unfrcquently withstand every sort of treatment. (See Ricord's treatise
on Syphilis, edited by Dr. Turk, and also Ritter's Chronic Gonorrhoea). Mayr-
hofer.
Thuja Tincture for Condylomata. 127
sycosis ; in many cases 1 nave found its external application unnecessary,
especially to soft condylomata. But wartlike excrescences with horny
points on their surface require the external use of equal parts of alcohol
and Thuja-juice, and also the subsequent internal administration of nitric
acid."
Wo add in this immediate connection the communication of a follower
of the old school upon this same disease, because observations made
upon the same subject by men of opposite views, are stringent proof of
the truth of those matters wherein they agree.
On the internal and external use of Tinct. Thuja? in cases of condylo-
mata, by Dr. Warnatz (Monatschrift fur Med. dr. 1838, B. 1. H. 2).
" Every practising physician must have experienced the intractability and
the liability to return, when surgically treated by excision, of condylomata,
those lymphatic vascular excrescences in the rete vascidosum of the skin'
lying near the mucous membrane of the rectum and genital organs, which
appear originally as symptoms of secondary syphilis.* The author resided
in a district where among a part of the country people secondary syphilis
is not unfrequent, and appears pretty often in the shape of condylomata
about the anus and genitals. Among these again, those with broad and dry
surfaces, were disproportionately more frequent than those with pointed
sore and secreting ones. Such patients often continue to bear the disease'
for a long time without its apparently exerting any very great influence on
their general health, until excoriation, pains, and the extension of the ex-
crescences oblige them to seek the aid of a physician. Then the most
minute investigation frequently detects not the slightest trace of syphilis
except the condylomata, which in women, however, are commonly accom-
panied by a suspicious vaginal blennorrhoea, and it is often exceedingly
doubtful (especially after a severe mercurial treatment) whether we are°to
regard the original disease as still present in the cutaneous excrescence or
whether it has set up in this shape a new form of disease. We certainly
saw many cases cured under the employment of the best known remedies
as under Dzondi's treatment, under the Louvrier-Rust inunction, under red
precipitate (without cauterisation of the condylomata). The well known
external applications, either purely caustic or such as tend to produce an
alteration in the morbid process, were also used, as Lapis infern., Lap.
caust., Cupr. sulph., Liquor hyd. nil., Sol. tart, emet., Acet. salurni, Sabina.
Plenck's solution of Sublimate, Camphor and Alcohol. In many cases how-
ever, the re-action thus excited was too painful and even not without danger ;
sometimes they could not be employed from domestic and matrimonial con-
siderations ; sometimes the knife was finally necessarily resorted to and then
the disease returned, especially, according to W.'s observation, in young and
plump individuals." f
* It is still a question whether condylomata are forms of primary or secondary
syphilis, or whether they may not be both. The thing becomes much simpler to
those physicians who recognize the distinction between the gonorrhoeal and chan-
crous sickne»s. — Mayrhofer.
t Condylomata, the result of gonorrhoea, defy the therapeutic triad of the old
school, Mercury, Caustic and the Knife. — Nay, Dease has remarked that they did
not disappear though the patients were so long salivated that they died of maras-
mus, thus verifying Hildebrandt's remark, " Sunt medici qui morbos construunt
et aegros destri^Rf.^ — Mayrhofer.
12S Tliuja Occidentalis.
" It is very possible, however that in many cases new and repeated sy-
philitic infections may have taken place which have been concealed from the
physician so long as they were new. Unfortunately, in relation to the mo-
ral conduct of such patients, "quilibet preesumitur malus" must be the
physician's guiding maxim."
" Two years since, the author was especially annoyed by a patient so af-
flicted with condylomata that none of the usual remedies were of the least
avail. On account of the original syphilitic infection, the patient had al-
ready been through a course of inunction, but without any result as to the
condylomata. W. then recollected that Hufeland, in his '■ Journal fur pract.
Heilk." recommended the external application of Thuja to condylomata, and
he resolved to try its effect/'*
" For four weeks in succession, the warts upon the scrotum and perinccum
were painted three times a day with the alcoholic tincture of Thuja ; the
cure which followed is perfect to this day, and no other syphilitic symptom
whatever has appeared. W. employed the same remedy in the same way
and with similar results with several patients, and finally resolved to try
what effects might be expected from its internal use. He administered
it internally in several cases of broad condylomata twice, from eight to
sixteen drops, and at the same time employed it externally with astonish-
ing success. In several slight cases, a perfect cure followed from the in-
ternal exhibition alone. The author relates the following case :
" N. N., a stout country girl, 29 years old, as the result of an impure coitus,
had suffered for over a year with syphilis univ. (showing itself chiefly in
the cutaneous system), and had undergone such a profusion of doctors
and doctors' drugs that her pecuniary means, at best but scanty, were pretty
much exhausted. On examination he found small chancres (mucous follicles
of the vagina in a state of ulceration), a tolerably copious leucorrhoea, with
discolored, offensive secretion, and very extensive condylomata lata. The
anus and posterior portions of the labia pudenda were covered with a broad,
cauliflower-like excrescence, consisting of broad, slightly reddened, but
otherwise almost dry condylomata, so that the anus had precisely the ap-
pearance of the external genitals with long, elevated labia externa. Besides
these, there were, neither in the throat nor any* where else, any traces of
syphilis to be seen. She was received into the Charity Hospital in Camenz,
in Upper Lusatia. The physicians of the establishment, Dr. Roderer, and
the author's father, Warnatz, employed various mercurials, and even inunc-
tion, without any effect upon the condylomata. The ulceration of the va-
ginal mucous membrane and the blennorrhea had indeed almost disap-
peared, but the condylomata were unaltered."
" Thuja had already been employed externally on the recommendation of
the author, but without result. He now advised the internal exhibition of
the tincture of Thuja without delay in a dose rising from eight to sixteen
drops twice a day. The external use of it upon the condylomata was con-
tinued. The case was tedious but the result was striking. After pursuing
* Hufeland could only have recommended Tliuja for condylomata upon Hahne-
mann's authority, for he, as the first prover of Thuja, recognised its specific virtue
in sycosis, and employed it for that affect'on. Our opponents have, ever since the
first promulgation of Homceopathy, been in the habit of helping themselves to ho-
moeopathic dainties and nicknacks. Their pretended ignorance, evasion, or con-
cealment of the homoeopathic source we must decidedly condemn, as a violation of
the right of property which Homceopathy is in duty bound to maintain. Cuique
suum. — Mayrhofer.
Condylomata. 129
this course for three months a perfect cure was obtained, not only of the
condylomata but also of the vaginal blennorrhcea.
" Altogether W. has treated 16 cases, fourteen of the broad and two of
the pointed condylomata. These latter remained uncured, but rapidly dis-
appeared on exhibiting Liquor hyd. nitr. externally, and sublimate internally.
Eleven of the fourteen cases of broad condylomata were perfectly cured.
Of the remaining three cases, one still retained small warty fragments,
which the author excised, and in the other two no change was perceived ;
it ought to be remarked, however, that one of these patients had been cured
by Thuja a year before, but when the disease appeared anew no cure was
obtained." *
" In eight cases the remedy was applied exclusively internally ; i a eight
both externally and internally. Internally the dose was from six to sixteen
drops of the pure drug taken twice a day; externally it was painted on
three times a day with a fine brush, until, by and by, burning, excoriation
and slight secretion from the condylomata came on. If they were sore and
excoriated at the commencement, the application of the remedy occasioned a
pretty severe burning pain. Finally, it is not possible, by the closest atten-
tion, to observe the farrago symptomatum which the Homoeopaths pretend
to have noticed as effects of this drug.f Patients who took the remedy in-
ternally perceived a feeling of burning and warmth in the mouth, throat, and
on the tongue, extending into the precordial region, but this soon passed
off. No special operation on the digestive organs or bowels was observed;
but in several cases nocturnal cutaneous excitement and increased urination
seem to have been produced." J
" A slight itching was the only remarkable feeling in the condylomata,
which is, however, rather to be ascribed to the perinaeal sweat." §
The patients did not complain at the commencement of the treat-
ment when the Thuja was applied to the dry condylomata; after se-
veral days' application, when the skin had become thin and excoriation
had commenced, they only felt a little burning. At the same time the
warts reddened somewhat, and showed some, though little secretion,
which appeared to be the especial agent of cure by the outward appli-
cation of Thuja. The author, however, has never seen those violent ef-
fects from the external use of the drug which Dr. Fricke of Hamburg
has observed, in whose practice, though using it in a diluted form, it
caused such remarkable irritation that he was obliged to lay it aside.
Fricke saw considerable swelling and excoriation of the whole neighbor-
* It is very probable that Sabina, externally and internally applied, would have
effected a cure in* this ease. — Mayrhofer.
t The apparent confusion of symptoms in the Hahnemannian system is the
greatest stumbling-block to the physicians of the old school. They find it much
more convenient to reject the good with the bad than to subject themselves to the
trouble of studying the character of a remedy from the physiological proving, or of
making experiments with drugs upon their own bodies. As to this case, the few
drops of Thuja exhibited produced few primary symptoms, because their powers
were exhausted in combating a disease to which the drug was perfectly appropriate.
— Mayrhofer.
% These observations agree perfectly with our provings. — Mayrhofer.
§The sweat on the genitals belongs equally to the operation of Thuja, as "our
provings testify, and itching and tickling in the condylomata under the use of Thuja
have already been observed by Hahnemann. — Mayrhofer.
K
130 Thuja Occidentalis.
hood where it was applied, follow in every case. Diluted, the remedy
produced no results, and only in one case was he able to effect a te-
dious cure. {Casper' 's Wochenschrift, 1844, N. 24.) The experience
of Dr. Kohler of Warsaw is somewhat opposite in character. He never
witnessed inflammation, excoriation, or even unfavorable influences or
relapses * after the employment of the drug. The same was the ex-
perience of Dr. Leo of Warsaw. He constantly associated the internal
administration of mercury,f however, with the external use of Thuja.
{Fleker's Annalen, <fec. 1835. H. 3.) The author does not know of
any other observations that have been made public.J The author does
not permit himself to form any opinion upon the pharmacodynamic
character of Thuja ; since for this, still more extended experiments are
necessary, which are to be expected from the heads of great clinical
institutions. § He has communicated the little experience he has had,
without prepossession and without any sympathy for Homoeopathy, || but
simply because he conceives it to be the duty of every physician to con-
tribute, according to his ability, to that common good of all, the exten-
sion and advancement of science.
* Diversity of effect depends upon the relative irritability of the individual pa-
tients. Thus the tincture of Thuja will produce no unpleasant consequences in a
torpid patient, while in one who has a well marked susceptibility to this drug, even
dilutions will produce violent reaction. The quantum of the drug must be taken
into consideration in relation to the individual no less than the quale. If Dr. War-
natz is of the opinion that Homoeopathy consists in small doses (a notion with which
homceopathising allopaths would fain quiet themselves and others) I beg him to
know that Hahnemann himself directed the application of the Thuja tincture to
condylomata in the oldest and most inveterate cases (Chron. Krank. Heil. der Sy-
cosis). — Mayrhofer.
t In order to keep up the art of hodge-podge, and to secure the certainty of a
doubt as to which remedy effected the good. — Mayrhofer.
i Because the author had neglected to acquaint himself with the literature of Ho-
moeopathy, of which many of the physicians of the old school are still ignorant. All
those physicians who neglect the study of Homoeopathy richly deserve the reproach
of onesidedness, and so long as candidates for a degree are not examined on the
learning of the new school, so long will our public examinations supply us with only
onesided priests of ^Esculapius. — Mayrhofer.
§ We cherish like hope with the author. But unfortunately, Homoeopathy com-
mands as yet no syphilitic dinique, and to all appearance will wait long before she
attains so desirable an object. — Mayrhofei .
|| This protest against Homoeopathy is a sufficient proof of the prejudice of the
author. He who cures condylomata with Thuja is a homoeopath, because his treat-
ment is founded on the principle " similia similibus," and in truth, he takes part
in Homoeopathy. Before the world, indeed, he may be an avowed or a secret ho-
moeopath, or even a homoeopathic smuggler, according as he is honorable enough
to acknowledge or 'weak enough to be silent respecting his faith, or so destitute of
principle as to plough with another's heifer and read by another's candle without
acknowledging his obligations to the owner. Homoeopathy, however, by this time
should be well accustomed to the treatment of her rationalist opponents, slappin"-
her in the face with one hand and picking her pocket with the other. — Mayr-
hofer.
Sycosis. 131
1. Uncomplicated Sycosis.
Dr. Trinks relates the following case of primary sycosis.
1. A young man was exposed to contagion by a coitus and eight days
after, comblike, horny excrescences appeared upon the inner surface of the
prepuce. Trinks diagnosed these excrescences to be condylomata, but the
patient, not having confidence in this opinion, consulted another (distin-
guished) physician of Dresden, who diagnosed Trinks to be an ignoramus
(allopathic professional courtesy ! M.), and quieted the patient with the
assurance that the excrescences were the result of too violent rubbing and
erosion of the prepuce (sub coi'tu) and that they would soon spontaneously
disappear. Thus comforted, the patient departed on a journey, giving no
thought to his ailment; but on returning home, at the end of six weeks, he
found to his horror that the excrescences had considerably increased both in
number and in size.
The formerly incredulous physician now declared them to be condylomata.
But the patient declined his treatment and sought aid of Dr. Trinks. The
horny condition of the excrescences led him to the external and internal use
of Thuja, which worked a perfect cure in six weeks. — Annal. der horn. Klin.
1, s. 177.)
Tietze (surgeon) communicates the following cases {Op. cit. s. 369,
370):
2. A man 30 years old, blond, lean, of middle height, had suffered several
years from sycosis. He was treated with mercurial remedies, whereupon
the condylomata vanished, it is true, but soon came to light again. Driven
in again by the local application of quicksilver, the excrescences soon re-
turned. Thus passed several years, the patient keeping constantly by him
a pot of mercurial ointment in order to daub over them wherever they broke
out next. When he consulted Tietze he complained of vertigo, eructations
after eating, grumbling in the abdomen, burning in the urethra, especially
morning and noon. There were several warts on the corona glandis which
became moist during the increase of the moon, and discharged a purulent
fluid. He had also cough with discharge of yellow mucus, severe thirst,
and twitching of his limbs in sleep, perspired much, and complained of
fatigue in his legs. On the 10th of July, 18*8, he took a dose of Thuja 30 :
this was repeated at the end of a fortnight, and on August 10th he had
three pellets moistened with Acid. nit. 24.
In the beginning of September the condylomata had disappeared, and at
the end of the month, even the marks on the skin where they had been.
The chest trouble was gone. He married, became the father of a sound,
hearty child, and experienced nothing more of his tedious complaint.
3. A strong young man had had for a long time two warts upon the pre-
puce nearly as large as peas, which, however, occasioned him no inconve-
nience. Dr. Rummel gave him on the 18th of February four doses of
Thuja 30. Six days after, no change being perceptible in the condylomata,
a considerable swelling made its appearance in the cheek, threatening to
end in suppuration. The patient took one dose of Mercury 15, whereupon
the abcess in the mouth broke and the swelling disappeared. Freed from
this interpolated disease, the patient again took advice in respect_ to the
warts, and received two pellets moistened with Thuja 30, with the direction
to dissolve them in a glass of water and to take a table-spoonful a day. Ten
days after, the patient came in consternation to his physician, with the story
132 Thuja Occidentalis.
that the whole glans was covered with pus. Rummel recommended him to
put dry lint between the glans and prepuce, and to do nothing else.
After an interval of two days the genital organs were found entirely freed
from warts. No trace of a scar could be discovered and he continued per-
fectly cured of sycotic affections. — (Allg. horn. Zeil. B. 5, s. 102.)
4. A young man, two years before, had contracted a gonorrhoea, and when
this was finally suppressed, it was succeeded by condylomata about the
anus, which he at first neglected and afterwards bunglingly treated on his
own responsibility. When he applied to Dr. Schindler, in January, 1 833,
the whole perinseum as far as the scrotum and around the anus for a breadth
of two inches was beset with large moist condylomata. He complained of
violent burning and biting and could scarcely walk. No improvement re-
sulted from a dose of Thuja 30 ; Acid. nit. 30, somewhat diminished the
burning.
From February 24th to March 16th the patient took every eight days a
dose of Thuja 30. The warts ceased to be moist, appeared to become
smaller, and he could walk better. Nitric acid 30, one dose every eight
days. The improvement progressed visibly; several small warts disap-
peared, the large ones became flatter, the burning and biting entirely ceased.
April 28th. The patient again had four doses of Thuja 30 to be taken at
intervals of eight days; the. most of the condylomata disappeared except the
larger ones: one pair only was left of those on each side of the anus.
Another four doses of Thuja produced no further improvement, and four
doses of Phos. ac. remained similarly without effect. Dr. Schindler gave
now a dose of Sulph. against any possible psoric complication ; the disease,
however, on the 19th of August, was at the point where it had been at the
end of April. The patient now took every morning a drop of the pure
Thuja and also applied lint moistened with Thuja externally.
August 27th. Every trace of condylomata had disappeared, the skin was
smooth, and the patient perfectly cured. — (Allg. horn. Zeit. B. 4, s. 276.)
Dr. Rummel gives the two following cases of sycosis. — (Archiv fur,
d-c. B. 8, H. 1, s. 58, 59) :
5. In the first case urethral gonorrhoea was also present, and the whole
scrotum was beset with hard, only partly moist tubercles. A cure followed
the exhibition of one dose of Merc, and two doses of Thuja (strength not
stated) and the external use of the juice.
6. A young man applied to Dr. Rummel by letter, requesting him to re-
move an ulcer upon his penis consequent upon contagion ; from the des-
cription, Rummel concluded that it was a chancre, and prescribed Mer. 12.
No improvement following after a fortnight, and the cure still lingering after
Acid. nit. 12, he insisted upon seeing the patient. Autopsy showed it to
be sycosis. Two condylomata were secreting an offensive purulent mucus,
and the patient stated that he had perceived a painful erosion (but decidedly
no chancre vesicle) the very next day after the copulation. There was be-
sides in the left axilla a dry, brown elevation, such as Hahnemann has des-
cribed. On the 24th of December the patient took Thuja 30, on which the
condylomata perfectly disappeared in three weeks. The brown, herpetic
elevation in the axilla, however, remained unaltered, and first vanished after
a dose of Acid. nit. 18. The exhibition of Thuja eradicates condylomata
with brown spots under the arms. — (Allg. horn, Zeil. B. 1, s. 96.)
7. Dr. Lobethal cured an officer of cuirassiers of an entire circle of
condylomata around the anus by the use of Thuja 1 (drop doses) alter-
Sycosis. 133
nated with Acid. nit. 3 and the external application of the tincture, in
some months after the patient had received no benefit from small doses
of the same remedy administered by another homoeopathic physician.
Dr. Mohnike relates an interesting case of obstinate sycosis cured by
Thuja — (Huf eland's Joum. March, 1843. Extracted into the Oest.
Med. Wochenschrift, 1843, No. 21.)
8. In the autumn of 1839 there applied to Dr. Mohnike a young merchant
who some two years before had contracted a violent urethral blennorrhcea
from an impure cohabitation. He had never previously had syphilis, and
this gonorrhoea even, after a few weeks' use of copaiba, had disappeared.
But scarcely two months had elapsed before the warts and excrescences
were gradually developed, from which he had now suffered for nearly two
years, and against which no remedy seemed to make head. The patient
was thus led to believe that his case was incurable, and had made up his
mind, as a last resort, to try the water cure at Graefenberg, provided Dr.
Mohnike's treatment was ineffectual. The examination of the patient de-
veloped the following facts ; the inner surface of the prepuce and the por-
tion of the penis behind the glans were, as it were, sowed over with nu-
merous pointed condylomata. These excrescences of the mucous membrane
lay prostrate on the spot whence they had sprouted, but when Dr. Mohnike
raised their heads with the forceps, the thin pedicle appeared of nearly a line
in length. The exudation of the offensive clammy moisture peculiar to
condylomata could only be detected in a very slight degree. The patient
had never felt pain or itching in the glans and foresldn. He had had no co-
habitation since the appearance of the condylomata. The perinseum was oc-
cupied in its whole extent between the scrotum and anus by a large condy-
lomata latum. It was certainly half an inch high, and extended on both
sides of the raphe. It exuded much, and was covered with a greasy puru-
lent moisture. The patient complained that he could often scarcely endure
the torture when walking, and that the innpr and upper part of the thigh
was often sore and inflamed from the acridity of the discharged fluid.
A similar broad condyloma, but smaller than that in the perinajum, was
found on the inner surface of the left thigh. The orifice of the anus, where
the skin meets the mucous membrane of the rectum, was surrounded by
three large condylomata lata, which simulated hemorrhoidal protuberances.
They exuded much, and constantly occasioned a very painful troublesome
itching, but intolerable pain when he had a hard stool. Finally, behind the
anus and on the coccyx there was an excrescence resembling the others in
size and condition. He had never experienced pains in the bones, and the
most careful examination of the oral and faucial cavity could detect there
no indications of secondary syphilis. He had already taken Zittmann's de-
coction and Dzondi's corrosive sublimate pills. Besides this, the most
varied sorts of caustic had been locally applied to the warts, and even exci-
sion and the ligature had been tried. But external and internal treatment
was equally unavailing.
Mohnike almost despaired of obtaining a perfect cure. He prescribed in-
ternally Bergs formula of Stib. sulph. nig. with Hyd. prccc. rub., which has
often proved serviceable in confirmed lues, especially where the skin and
mucous membranes are affected. The patient was ordered to lie abed the
greater part of the day, and to promote the cutaneous transpiration by fre-
quent drafts of an infusion of Spec. Lignor., with a spare diet. In addition,
Dr. Mohnike used Plenk's solution of sublimate, with which he cautiously
134 Thuja Occidentalis.
touched the warts on the glans and prepuce once a day for a week. The
broad condylomata, except those at the anal orifice, he covered with lint,
saturated with the same solution. All to no purpose. He now threw
aside all caustic applications and waited to see if internal treatment alone
would not effect the cure, but with similar result. He then resorted to the
use of tincture of Thuja, and soon had reason to be amazed at the rapid,
scarcely hoped for action of the new remedy,* for already on the third day
after the whole condylomata had been several times daily painted with the
tincture, they presented an entirely altered rppearance; they shrivelled, fell
in, and sensibly diminished in circumference. On the fifth day of the treat-
ment all the pointed warts upon the glans and inner surface of the prepuce
had disappeared. The smallest remains of the broad perinaeal condylomata
were visible on the ninth day. The tincture occasioned but little pain, and
the sound skin at the base of the warts was neither inflamed nor irritated.
The excrescences all disappeared by absorption, and without ulceration or
gangrene.
2. Sycosis with Rhagades.
A case of this kind is related by Dr. Genzke of Parcbim. — {AIL
horn. Zeit. B. 22, s. 22.)
1. A young physician had contracted by contagion a gonorrhoea, which
disappeared under the use of Balsam of Copaiba. One year after, violent
burning came on in the anus, which became intolerable when walking or at
stool, and an offensive moisture distilled which soiled the linen. Examina-
tion showed a shining mulberry condyloma, with a broad base close to the
anal opening ; and on both sides of the anus, in the natural folds of the skin,
two deep fissures (rhagades), which, as well as the condyloma, secreted an
exceedingly foul fluid. A colored yellowish brown ring two inches broad
surrounded the anus. Dr. Genzke prescribed the first dilution of Thuja,
with directions to take one or two drops a day in the morning, fasting, and
to paint the wart and fissures with the tincture. In fourteen days the burn-
ing had almost completely disappeared, the condyloma was visibly wrinkled
and had lost its polish, the rhagades were smaller, the foul secretion had be-
come less and inodorous, and in short, all the local symptoms progressively
diminished. The patient, however, a novice in Homoeopathy, mistrusting
the small doses, took larger ones than were directed, and experienced press-
ing aching in the forehead, restless unrefreshing sleep, and a well-marked ba-
lanitis. The glans was in its entire circumference swollen, inflamed, co-
vered with small pimples, and discharged a tolerably copious purulent se-
cretion.f The Thuja was omitted, and four weeks' after the beginning of
the treatment the whole train of symptoms, both of the disease and of the
remedy, had vanished.
* We must class Dr. Monhike too among the homoeopathic freebooters, because
he does not state the source whence he obtained his new wisdom. If the remedy
was good enough to effect in a few days a cure where the so-styled rational treat-
ment had proved, for years, inefficient, it surely was good enough to have beea
openly acknowledged as a homoeopathic remedy. — Mayrhofer.
t Balanorrhcea is an effect of Thuja beyond a doubt, as I can substantiate from,
my own experience. — Mayrhofer.
Sycosis and Syphilis. 135
3. Sycosis co-existent with Syphilis.
Dr. Schron gives us an instructive case of Sycosis and Syphilis com-
bined.— (Ally. horn. Zeit. B. 5, s. 147.)
1. A girl of sixteen years old had leucorrhoea and bean-shaped warts, es-
pecially about the anus. Schron (then an allopath) subjected her to a
course of sublimate pills, and in the meanwhile removed the warts by the
knife. She was afterwards treated by another allopath, likewise with mer-
cury; but the warts and leucorrhoea never entirely yielded. In January,
1833, she again applied to Schron. She had on each side of the nose along
the cheeks two chancres of the size of a ducat, which extended into the
nostrils and presented elevated red margins and a tallowy bottom. * There
lay about the anus a collection of cockscomb-like warts which discharged, and
occasioned Ruch a burning that she could not lie in bed at night. The leu-
corrhoea reddened the thigh. Schron gave Merc. viv. 3 (£ grain), alternating
it with Thuja 3 (1 drop) every eight days, and applied the undiluted tinc-
ture externally upon the condylomata. In six weeks the chancres healed
entirely, and, in twelve, warts and leucorrhoea had both disappeared. The
burning in the condylomata first diminished, then they ceased to discharge,
and finally they shrivelled into mummies and vanished.
2. A peasant girl, 30 years old, had in September, 1844, a soldier on fur-
lough for a lover, and a fortnight after his departure she felt violent burning
in the anus and a corrosive leucorrhoea set in. Soon after she remarked
little tubercles about the anus which were painful to the touch and when at
stool. She consulted a country midwife, who examined her and said she
had piles. She went with this opinion to a barber surgeon, who treated her
for the piles. But the tubercles becoming constantly larger and more abun-
dant, moist excrescences appearing also upon the genital parts, and an ulcer
coming on the right thigh, she consulted an obstetric practitioner, who exa-
mined her and prescribed (Nov. 18) fifteen grains of Merc, solub. Hahnem.,
made into thirty pills with extract of liquorice, of which she was to take
every evening.
The ulcer, indeed, healed under the use of the pills, but the excrescences
continued to spread. In 1845 (March) the patient came to me. Examina-
tion showed a countless number of condylomata. Round the anus was a
ring of broad, soft, cracked, moist condylomata. The whole perinseum was
crowded with a host of warts, which had become confluent, and so formed
one great condyloma latum. Between the labia externa and the thighs a
double row of condylomata ran up on both sides to the mons veneris. The
labia majora were inflamed, much swollen, and covered internally and ex-
ternally with warts of all sizes. Finally, there were solitary condylomata
down the inner side of the thigh almost to its middle. It was, in truth, a
disgusting sight, for the number of warts must have been over a hundred.
The vaginal blennorrhoea corroded the thigh. She felt burning in the con-
dylomata ; the catamenia had ceased during the disease.
I gave twenty drops of Thuja 2 in six ounces of water, with directions
to take a table-spoonful three times a day. On the 7th of April the patient
returned with the news that she was much improved. The burning was
much diminished ; the condylomata discharged less and looked shrivelled
and perishing ; the swelling of the labia and the leucorrhoea were less. On
* Were these chancres the consequence of the oiiginal infection, or had a new
contagion taken place in the mean time ? — Mayrhofer.
136 Tliuja Occidentalis.
the 13th the patient had another vial of Thuja 2, upon which the ameliora-
tion proceeded and the menses appeared. I now gave her the tincture, one
drop three times a day, internally, and directed her to moisten the condylo-
mata with it morning- and evening. By the end of May over half of them
were gone, and as the cure seemed to be at a stand I gave her Acid. nit. for
a week (a few drops in six ounces of water, one spoonful morning and
evening).
The arbor vitcc operated with renewed energy after the administration of
the niiric acid, which last produced but little alteration in the disease. The
solitary warts vanished completely in June, and the complex ones were re-
duced in size one-half. All the other troubles were much lessened.
In July the girl fell from the thatch of the cottage upon which she was
spreading hemp to dry, and injured herself so severely that she was neces-
sarily treated for the consequences of the fall for a month after. In August
I made an experiment with the tincture of Sabina, and had the condylomata
painted with it daily, in order to see if in this neglected condition the sa-
vine would not hasten the cure. This was not the case. ] was obliged to
have recourse again to Thuja, under the persevering use of which all the
morbid symptoms ceased, and the condylomata disappeared, except a small
spot on each side of the anus, toward the perinseum, where the colony for-
merly existed.
In October the patient took no more Thuja, and I cannot say whether
these last traces of the condylomata finally disappeared or not ; we may,
however, judging from the rapidity of the cure up to that time, almost
certainly conclude that they did.
I may also remark that the patient, who entirely despaired of a cure in
the commencement, exhilarated by her progress, may have taken the doses
stronger than they were directed ; in the second month of the treatment
she exhibited, as signs of the operation of Thuja, single large vesicles
upon the thighs and arms, which were surrounded by a red areola and
passed into suppuration.
4. Sycosis after the cure of Syphilis.
Dr. Portalius relates a case in which condylomata succeeded to the
cure of syphilis. — {Arch, fur horn. Heilh. B. 19, H. 3, s. 80 et seq.)
1. Mr. M. had two large genuine syphilitic ulcers on the prepuce. No
signs of sycotic affection were to be perceived on a daily examination.
Both chancres healed in eight days (from the 13th to the 22d January),
during which time the patient took daily one dose of Merc. nig. 12., kept
strict diet and lay abed (two absolutely indispensable conditions, if syphi-
litic affections are to be rapidly and permanently cured). Five days after
the perfect healing of both chancres, condylomata sprouted luxuriantly
upon the frenulum pmputii, which were cured by Thuja. (Tt is not
stated what dose was given nor in what time the cure was effected.
Mayrhqfer.)
Tietze relates an analogous case.
2. A stout girl had suffered from a very copious leucorrhcea since her
delivery a year before; it was accompanied by violent itching on the ge-
nitals. On inspection, the labia majora were found considerably swollen,
and numerous ulcers with pale, tallowy bottoms, from the size of a lentil to
Sycosis. 137
that of a groschen, covered not only the external organs of generation but
also stretched deep into the vagina. Their syphilitic character was unde-
niable. She took daily Merc. nig. 12. After a fortnight a considerable
improvement appeared, and the patient took from the 10th of August to the
18th September, six doses of Sulphur 30, which not only removed the
leucorrhoea, but perfectly healed the remains of the ulcers.
Fourteen days after, however, such a profusion of condylomata had ap-
peared that the whole presented a most shocking sight. Even on the right
corner of the mouth there was a wart. She took externally Thvja (tinc-
ture) and internally Thuja 30, every day. The treatment was interrupted
by many accidents, but resulted in a perfect cure at the end of three months.
5. Masked Sycosis. (Radetzky's case.)
1. An illustrious personage, seventy years of age, had frequently suffered
for many years from a cough, which since 1836 increased in autumn to an
inflammatory catarrhal fever, and yet no pulmonary lesion could be detected.
In that year he broke two ribs by a fall ; the accident was followed by a
very violent pneumonia which ceased after purulent and offensive sputa.
During the two following years he was not seriously sick ; he had at times,
as he had had before, attacks of headache in the forehead, sour eructations,
and diarrhoea, which however were soon cured. In July and August, 1839,
cephalic congestions with violent vertigo often distressed him, and to these
were soon added pressure in the forehead and in the right eye, with inflam-
mation of the eyelids, watering and protrusion of the eye. By appropriate
remedies the affection was indeed diminished, but the under lid still re-
mained inflamed. On the 9th of October, 1840, the patient (a distinguished
military officer) sat on horseback five hours in the sun ; in the evening he
was attacked with violent fever accompanied by intolerable pain in the
forehead over the right eye. This latter was much inflamed and protruded
somewhat from the orbit. The fever soon disappeared ; the trouble in the
eye too was somewhat lulled, but there still remained inflammation of the
lower lid, watering of the eye, and a swelling at the external canthus back
in the orbit, which was not painful nor did it interfere with vision.
Toward the end of October, the patient went on a journey and only re-
turned after an absence of six weeks. During this time, there had arisen
in the eye a vegetation of the size of a bean, which, commencing in the
internal canthus, extended along the under lid. The tumor already exists
ing in the external canthus had enlarged, and the eye was considerably
protruded from its socket. Occasional headache in the forehead and
violent congestions were also present. The domestic physician of the
illustrious patient, Dr. Hartung, considered the case as a critical one, for it
was his opinion that a fungus had formed in the orbit, the development of
which he dreaded.
The homoeopathic treatment now commenced had no special issue ; the
general strength was preserved by the various remedies employed, but the
growth of the fungus could not be stopped. The tumor over the external
canthus had now a purplish color, and both it and that in the internal
canthus had increased, and there appeared between the ball of the eye and
the under eyelid a fungous, elastic, pale, red, painless, spurious growth,
which pressed the ball out of the normal axis of vision. The pupil was
directed upwards and outwards, and the free motion of the eye impeded,
but the power of vision was as yet unimpaired.
138 Thuja Occidentalis.
An oculist, called into consultation on the 6th of January, 1841, confirmed
the diagnosis of the ordinary physician, and gave a very unfavorable pro-
gnosis, declaring " that there was nothing to be done in the case, and that
no method whatever could effect a cure." At Hartung's solicitation that
he would at least recommend something, he prescribed corrosive sublimate
(a quarter of a grain daily), at the same time remarking "that it would do
no good, but he knew nothing better." Dr. Hartung acquiesced in the
prescription, but from caution administered only one-twelfth of a grain
(whether only once or oftener is not stated), but was immediately obliged
to give an antidote on account of the violent cephalic congestions that
came on.
On the 26th January, 1841, Hartung describes the state of the disease as
follows. — (Allg. horn. Zeit. B. 20, s. 145 et seq.)
A hard grayish blue tumor filled almost the whole orbit and displaced
the ball of the eye outwards ; on the under lid it was clearly fungous, it
was painful under strong pressure, and bled easily ; the ball was pushed
against the external canthus and immovable. The patient perceived various
pains in the fungus, sticking, tearing, burning and itching. The eye itself
gave him no pain, but the visual power was so affected that every object
opposite the external canthus appeared black. The eyelids were also
stretched and swollen, black and blue, and immovable. The conjunctiva,
especially that of the lids, the plica semilunaris, and the caruncula lachry-
malis were loosened, of a dirty red, and covered by a thick tissue of vari-
cose vessels.
In the morning the crevice between the lids was filled with a white,
viscous, purulent mucus ; the eye watered in the daytime ; in the evening
it was hot, dry and painful. In other respects the patient was free from
febrile symptoms, and his strength and the vital functions of the organism
were as favorable as could be desired.*
The case now fell wholly to the charge of Dr. Hartung, as the patient
emphatically declared " that he would have no treatment but the homoeopa-
thic." Dr. Hartung employed at first, Ars., Psorin and Herpetin (all three
of the 30th dilution), but without result. The bleedings ceased after Carb.
anim. 30, and the fungus ceased to grow, but no amelioration followed.
Hartung now gave one drop of Thuja 30 in three ounces of distilled water,
a table-spoonful three times a day. On the first day appeared some remi-
niscences of the previous morbid condition, as, aching on the right side of
the forehead, nocturnal cough, slight diarrhaea, renal pains and itching on the
* The communications of the consulting physicians do not agree in relation to the
special diagnosis. The ordinary, in his account (loc. cit.) speaks constantly of a
fungous excrescence. Another physician, who was called in consultation, says
" that he had satisfied himself, by the presence of all the commonly reputed charac-
teristics of that disease, of the existence of a scirrhous metamorphosis," and a third
physician calls the affection, " Ophthalmiam syphiliticum ex schirro orbita syphi-
litica oriundam.''
Since we too have a right to express an opinion on the subject we take the liberty
of saying, that we consider the spurious growth in question as a sycotic excres-
cence, and upon the following grounds : 1. because the pathognomonic signs of the
disease point that way with the greatest probability (notwithstanding that the veil
that conceals the previous history of the case is not removed) ; 2, because the mer-
cury administered produced no amelioration ; and 3, because Thuja disprove the
specific — according to the allowed rule of probabilities, " ex juvantibus et non jus
vantibus judicium sumendum est.' 1 — Mayrhofcr.
Sycosis. 139
inside of the thigh with a miliary eruption.* These symptoms diminished
on the second day and vanished on the third. The local symptoms were,
itching in the inner canthus of the diseased eye, and secretion of a creamy
fluid about the whole circumference of the fungus. This result induced
Hartung to apply Thuja also externally. He caused the fungus to be
moistened every two hours with warm water (four ounces) containing six
drops of the tincture. On the fourth day after the exhibition of Thuja, the
pain in the eye had ceased, the secretion of the milky fluid had increased,
and the fungus was notably diminished, especially at the upper orbital
border. The amelioration steadily proceeded under the employment of
Thuja through the fifth, six and seventh days, and, to the astonishment of
all who had seen the disease earlier, the fungus in the internal canthus and
under eyelid disappeared. On the evening of the eighth and the morning of
the ninth days, the patient had a dose of Carb. anim. 30. The fungus was
also painted every morning for eight days with the twelfth dilution of Carb.
anim, and the Thuja baths were continued.
These two remedies (Thuja and animal charcoal) were now employed,
externally and internally, in eight day alternations.!
The result was so beyond all expectation successful, that within six
weeks the fungus, progressively diminishing, disappeared, the eye regained
its normal power of vision, the ball returned into its socket possessed of its
former mobility, and in short, a complete cure was effected.
Dr. Bartl relates a similar case of a fungous excrescence cured by
Thuja, which he had occasion to observe when physician to the Syphili-
tic Hospital at Palermo.
2. " A man was attacked with a panaritium upon the thumb after having
been cured of a balanitis by mercury. The inflammation terminated in sup-
puration, the abscess was opened, and a simple bandage recommended with
lukewarm ablutions. The wound not only did not heal, but became redder
and more sensitive, and burning pains came on in it.
" The remedies theretofore used, Puis, and Sulph., produced no result ; the
pains increased, especially at night, and a red, fungous, cauliflower excres-
cence began to show itself from the wound ; it felt hardish at the base, was
very sensitive to the touch, and bled slightly.
" Under the idea that it might be an excrescence depending upon caries, I
examined with a probe, but found the bone covered and sound.
"Touching with Lapis infern. was of no service; after twenty-four hours,
the fungus was again there, and increased even more luxuriantly than be-
fore; the same result followed with burnt alum." This fruitless treatment,
the previous disease, the form of the spurious growth, and also its accom-
panying symptoms, finally led Dr. Bartl to the well-grounded conjecture
that the fungus arose from a sycotic source, and induced him to employ
Thuja, internally at first, afterwards externally also. The result was, that
within a short time " violent inflammatory irritation aud suppuration was
excited in the morbid growth," by means of which the fungus, then of the
* Do not these symptoms still more indicate Thuja ? — Mayrhofer.
t We cannot gather with certainty from Hartung's account whether the drugs
Thuja and Carb. anim. were given separately in eight day alternations, or whether
the external use of Thuja was continued also during the week of the char-
coal, so that the fungus was only once painted with the Carb. in the morning and
then frequently through the day with the Thuja, which is most probable. — Mayr-
hoftr.
140 Thuja Occidentalis.
size of a hazelnut, melted away, and the man was discharged perfectly
cured.*
Dr. Biirtl takes occasion to make the following remarks on the use of
Thuja : I have found Thuja a very effective remedy in many forms of
disease founded on pure sycosis. I have especially cured with it, condy-
lomata which appeared on the inner surface of the prepuce or on the
glans in the form of cauliflower, after urethral gonorrhoea or bala-
norrhoea, were pale red, itched, and bled easily on being touched. I em-
ployed it in high dilutions and repeated doses until signs of increased
pain (in sensitive persons) and partial decay of the excrescence ap-
peared, which commonly manifested itself by gray or blackish points on
the surface ; I then caused the whole growth to be painted once a day
with the tincture. The condylomata dissolved in a short time by the
suppurating process and a perfect cure resulted.
6. Chancre Warts.
There are chancres which instead of eating into the depth of the tis-
sues, increase upward, and are cured either not at all or with great diffi-
culty by mercury, which shows their sycotic character.
Dr. Attomyr gives us two cases of this sort.
1. A man 31 years old had had a small, flat, tallowy ulcer for three days on
the inner surface of the prepuce. He took three doses of Merc. sol. Hahn.
4 to be taken every other day. The suppuration became greater, the ulcer
larger, and showed now a red bottom. He had four similar doses to be
taken in the same way. The chancre now rose above the surface of the
prepuce — it continued to rise more and more after two doses of Acid. nit.
3, taken every other day, but rapidly healed after three doses of Thuja taken
at intervals of two days. The whole treatment lasted 27 days. — Archivfur
homceop. Heilk. B. 18, H. 3, s. 141.
2. A perfectly healthy young man contracted a chancre on the inner surface
of the prepuce as the consequence of an impure connection. It disappeared
on the use of external and internal remedies, but, from time to time, little
aphthous ulcers appeared upon the glans and foreskin, which vanished spon-
taneously after from five to eight days.
At first, three such erosions appeared on the spot where the chancre had
been ; then by degrees came six more which were half on the furrow of the
glans, half on the prepuce. A new ulcer constantly appeared near the still
visible spot left by the one just healed. Once a spontaneous ulcer appeared
upon the external surface of the prepuce, and healed likewise of itself after-
it had been covered with a loose crust.
These symptoms induced the patient to submit himself to a rigid mercu-
* Dr. Ritter, in his essay on the essential difference between chancre and go-
norrhoea (p. 224), relates a case in which a violent inflammation of the testicle
(Epididymitis gonorrfwica) supervened on suppressed gonorrhoea in the case of an
officer ; the inflammation left the testicle hard and swollen. Nine months after in-
flammation and suppuration came on with increase of the pains and a fungous ex-
crescence grew from the testicles which soon reached the size of a goose-egg. AH
the remedies administered were of no avail, and the fungus was removed by liga-
ture. — Mayrhofer.
Warts. 141
rial after-treatment, but notwithstanding this, the occasional ulcers did not
cease to appear. Three years after he exposed himself to a second contagion
and was treated by Attomyr. In the beginning, five very flat, confluent ul-
cers were to be distinguished. A week later there where ten chancres, which
appeared, remarkably enough, upon the identical spots where the spontaneous
eruptions had been. In the fifth week of the treatment, a chancre appeared
on the external surface of the prepuce, which became covered as before with
a slight loose crust. The whole eleven became raised instead of becoming
deeper, and suppurated so profusely for full seven weeks that the patient
wasted.
At first Attomyr prescribed one drop Merc. sol. Hahn. 4 each day, and
because of the upward growth of the chancres, one dose of Acid. nit. 4
daily, for three weeks. As the suppuration did not diminish, however,
though the ulcers looked very clean, the patient had Thvja 3 one drop, at
first twice a day, then once a day, and finally every other day : the ulcers now
healed perfectly. The whole treatment lasted nine weeks. — (Archiv fur
horn. Heilk. B. 29, H. 2, s. 162 et seq.)
B.
Verrucae, Warts.
Thuja creates warts in those constitutions which are disposed to cuta-
neous excrescences, and must, therefore, under the proper conditions,
possess the power of curing them. The therapeutic indications and con-
ditions in this relation are : broad base, conical form, superficial seat in
the skin, cracked, mulberry-like surface, simultaneous presence of other
symptoms indicating Thuja. Warts, which appear after chronic go-
norrhoea, in the most diverse parts of the body, yield without a struggle
under the curative power of Thuja.
1. Dr. Frank of Osterode, who, fourteen years ago, was troubled
with many warts on both hands, which were rubbed with antimonial soap,
has had for some years on the left nostril a broad-seated, somewhat movable
excrescence, which he often caused to bleed by pulling, upon which an un-
pedicled wart was developed which reached the size of a large pea. Frank
rubbed this a couple of times daily with the tincture of Thuja.
After some days the wart became black, and developed many furrows
on its surface. Frank now removed with a knife the chapped surface and
left the excrescence alone. This increased again, which Frank had noticed
when he first applied the Thuja ; but the surface remained smooth, shining,
horny and uncracked.
He now again applied the Thuja externally in the manner already stated,
and on the very next day the same change took place in the form and color
of the excrescence as on the first occasion. He now proceeded less rapidly,
moistened the wart several days with Thuja, and then again ceased for a
while. The wart became smaller, and in four weeks (including the pauses)
the process of destruction was complete and the wart gone.
Dr. Huber* of Linz has observed two cases in which warts have been
cured by Thuja.
* Dr. Huber communicates these two cases as provings. They are, however,
cures with excessive action of the remedy, which had been administered in large
doses, with an eye to the proving. — Mayrhofer.
142 Thuja Occidentalis.
2. A boy 14 years old, of scrophulous habits, had numerous (30 to 40)
warts on his hands, and especially upon the back of his hands. Their size
was various, from that of a millet seed to that of a pea. The surface of
the smaller was smooth and almost translucent ; of the larger roughly
marked and cauliflower-like. Their consistence was not hard.
The boy had Thuja 1 on the 6th of October, 1844, with directions to
take five drops every evening, and at the same time to wash the warts daily
with the tincture of Thuja somewhat diluted. Although he used the re-
medy with great irregularity, yet on the 17th of November not the slightest
trace of a wart was to be seen ; the place where they had been, even, was
not to be detected by any change in the skin. But during the treatment
symptoms arose which we must set down to the account of Thuja : a very
severe, twitching, sticking toothache, which came on several days in bed, in
the evening, and disappeared every time in a quarter of an hour after a dose
of Cham. 1 ; also a dark-red tubercle on the edge of the upper eyelid close
to the internal canthus of the right eye. On the 13th of October it was
soft, became harder by degrees, on the 18th attained the size of a sweet
pea, after some days passed into suppuration, spontaneously separated, dis-
charged much pus, and healed without the aid of art.
3. A girl fourteen years old, with dark hair and eyes, and who had not
yet menstruated, had numerous warts on her right hand (20 to 25) which
were partly horny like corns, partly less hard and rough upon the surface,
partly smooth and small. She had besides on the back of the right forearm
near the wrist, a pale-red herpes of the size of a copper Kreuzer, covered
with little epidermic scales. She had Thuja internally and externally, at
the same time and in the same way as the boy. When she had taken over
thirty drops of Thuja 1, without experiencing any effect, she omitted the
internal employment of the remedy, but used it externally for five weeks.
The result was not so gratifying as in the case of the boy. Half of the
warts, indeed, disappeared, and those that were left became flatter and less
prominent, but they did not entirely disappear.* The cure took place in a
twofold manner ; in the case of three horny warts the subcutaneous reti-
cular tissue became inflamed, an abscess formed, and on its bursting the
skin and wart departed together. The small, smooth and soft warts be-
came by degrees flatter, and entirely disappeared by desquamation of the
two concentric cutaneous strata, without leaving a trace of their existence.
Dr. Huber afterwards made a second experiment of a week with, the
same girl, using internally the first dilution and the tincture. On taking
five and eigbt drops of the tincture on the two last days, the most
striking symptom was a tearing digging pain in the nape, aggravated
by moving the head ; in its greatest violence it became furious, and she
shrank from pursuing the experiment. This confirmed Dr. Huber in
the idea that the pain in the neck which had troubled him durino- his
proving, was truly caused by the drug.
"We have no account of any further changes in the warts, nor of the
condition of the tetter upon the arm.
4. Dr. Blodau gave Thuja 30 against warts in great numbers, succeeded
* Doubtless the horny warts would likewise have entirely disappeared under the
continued external and internal use of Thuja. Five weeks were not sufficient to
complete the cure. — Mayrhofer.
Warts and Excrescences. 143
by violent aggravation. A week after lie gave a pellet moistened with
Thuja 30, and four weeks afterwards the warts had all fallen off. — (Archiv
fiir horn. Heilk. B. 14, H. 2, s. 107.)
Dr. Gross relates a remarkable case of warts, with an accompanying her-
petic eruption. — (Archiv, <f-c. B. 15, H. 3, s. 37 et seq.)
5. A young man of about thirty years old, gave the following account of
himself in writing : " I am laboring under an herpetic eruption, which
spreads over my whole face. It shows itself, especially after being heated,
as red spots, which then throw off white scales, and is accompanied by
sticking, burning, and itching. Sometimes the eyelids are entirely covered
with it. I have, besides, weakness of the stomach, with acidity and eruc-
tation, inflation of the abdomen with flatulence, constipation, with burning
itching at the anus, palpitation of the heart, and occasionally pains in the
back. When a child I had an eruption on my head, and at fourteen and
twenty-one, on my face. At seventeen I perceived little elevations of the
skin of my hands, similar to warts, which increased from year to year in size
and number. At twenty-five I used some external remedy for them, after
which they disappeared ; after ten or twelve days, however, re-appeared in
this facial herpes, of which, to this day, I cannot get rid. I have already
taken tea for purifying the blood, sulphur, graphite, and mercury, but with-
out success. After six weekft' treatment in Carlsbad the tetters disappeared
for several months, but have now for a long time been re-instated."
Dr. Gross sent the patient eight doses of Ars. 30, with directions to take
one every fourth day. After taking these powders, the patient wrote that
there was no change in his condition, except that several warts had made
their appearance on his hands, but the tetter had not gone. Gross now
made choice of Thuja (dilution not stated), of which he sent six doses to
be taken at intervals of four days. The warts and tetter disappeared
together in consequence.
C.
Swellings and Excrescences on the Eyelids.
The general physiological character of Thuja is to create dermatic
growth and excrescences, by stimulating the cutaneous system ; these
may exist upon any part of the body. It also excites pains, irritation,
and swelling of the eyelids, suppurating tubercles on the eyelids and
brows. Those morbid affections of the eyelids which in ophthalmic me-
dicine are named from their varying forms Hordeolum, Milium, Cha-
lazium, Verruca, and Condyloma, become proper objects for the action
of Thuja, when their special symptoms, or the fundamental sickness of
which they are local manifestations, indicate its exhibition.
1. Dr. Bleifuss of Ochsenfurth treated a young lady who had scattered
Hordeola upon the eyelids.* The conjunctiva was sympathetically affected,
and her digestion was disturbed. She sought aid from every quarter, but
in vain. Iodium even produced no effect, and she began to think of extir-
pation. Dr. Bleifuss accidentally (! M.) read the symptoms of Thuja re-
corded by Hahnemann, applied the tincture externally, and beheld, with
astonishment, a rapid decrease of the disease. He now exhibited it inter-
nally (ten drops several times a day) and effected a perfect cure.
* They appear to have been Milia or Chalazia.— Mayrhofer.
144 TJxuja Occidentalis.
From that time Dr. Bleifuss learned to value Thuja, and subsequent-
ly wrought with it other wonderful cures.
" Let us pick," says he, " the grains of wheat out of this homoeo-
pathic chaff ! they are of excellent service to our therapeutics, as I have
frequently had occasion to be convinced." *
D.
Pains in the Limbs.
The arthritic pains which Thuja excites, especially in the limbs, are
among the most frequent and most constant of the symptoms during
the provings ; thej^ never entirely failed to appear in the most unsus-
ceptible and least productive provers.
The special curative indications are, drawing, tensive, tearing, twitch-
ing pains, appearing suddenly, confined to one spot or limb, or wander-
ing, aggravation in rest and warmth, amelioration by movement and in
the open air, and in feverish conditions, predominant cold with numb-
ness (deadness) of the affected limbs and desponding frame of mind.
Homoeopathic literature is still very poor in vouchers for the thera-
peutic virtues of Thuja in corresponding arthritic affections.
Dr. Mschk relates a single case (Annal. der horn. Klin. B. 1. s. 216).
A woman came crying and weeping to him, and begged him to cure her
of the violent pain from which she had suffered for a fortnight. The pain
was tearing, and extended from the right shoulder to the points of the
finders. She also felt twitching in the muscles, now here, now there, from
the top of the shoulder to the middle of the arm : the forearm and index
finger were, as it were, dead, the other fingers numb. The pain was most
severe on letting the arm hang down; in warmth, especially in bed at night,
the tearing and twitching were aggravated, but were better in the cold and
on motion. Perspiration produced an amelioration. Chills, with yawning,
came on after midnight, and sleep appeared late, and was disturbed by hor-
rible dreams. The patient frequently had tenesmus. She had an evacua-
tion with difficulty every two or three days only, and it was sometimes mixed
with blood. To these symptoms were added nocturnal thirst with sensa-
tion of cold in the arms, palpitation, and depressed spirits.
The patient had a dose of Thuja 27, with directions to return ; which she
* We thank our allopathic colleague for the honorable frankness with which he
has announced the source of his new knowledge ; he has thus nobly distinguished
himself from those physicians of the old school, who, as we have had frequent oc-
casion to remark, secretly appropriate the useful grain from the homoeopathic field
and openly denounce its whole produce as chaft', or who, dressed in borrowed
feathers, go cackling about as though themselves had laid the egg The daily
spread of homoeopathic dilettantism among allopathic physicians is indeed a most
striking indication, on the one hand, of the pharmacological poverty of the old
school, and on the other of the therapeutic wealth of the new; for what says the
proverb ? '' The robber is in need, but the robbed has plenty." But we must
most solemnly protest against any amalgamation of the physiological pharmacody-
namics of the new school with the casuistic pathological materia medica of theold
— Mayrhofer.
Intermittent Fever. 145
did not do. Her physician accidentally met her, and she excused herself for
her neglect by saying, that soon after taking the dose, her pains entirely
disappeared, and the other troubles so far vanished that she only felt some
weakness in the arm and fingers.
E.
Intermittent Fever.
We have seen that Thuja, in its perfect effects, develops a fever cha-
racterised by the predominance of the cold stage, to which sweat im-
mediately succeeds (Febris algida imperfecta), coming on mostly in the
tvening, seldom in the morning, commonly without thirst, seldom at-
eended with severe thirst, and manifesting a quotidian or tertian type.
Dr. Herrmann states in his treatise on the homoeopathic treatment of
intermittents (Annal. der horn. Klin. B. 2, s. 398) that in the year
1830, when, by the command of the Emperor Nicholas, he made some
homoeopathic experiments in a division of the Garde-Central Hospital
at Tulzyn in Podolia, the intermittents (which are very prevalent there,.
as an endemic, and commonly exhibit a very capricious character)
during one season of hot and dry weather assumed a very similar type-
Thus, the attacks began with cold shiverings, with external and internal
chill, in some cases with thirst, were immediately followed, without the-
intervention of a hot stage, by general perspiration.
In intermittents thus constituted, Thuja (the dose is not stated) ef-
fected a rapid cure ; but somewhat later, after rain had set in, thia re-
medy proved no longer serviceable.
These are the only cases which we have in relation to the employ-
ment of Thuja in intermittent fevers, and judging from the physio-
logical provings, it can but seldom be a specific in that disease.
Besides the cases already enumerated, Thuja promises to be useful in
the following affections :
1. In left-sided hemicrania of the fifth pair, especially of the frontal
branch, and in cerebral nervous affections, with the sensation as though
a nail were driven in, or a convex button pressed upon a particular spot
on the head (clavus hystericus).
2. In stiffness of the neck, with the feeling as though the muscles
were too short, especially if there be present any other symptoms which
point to Thuja.
3. In Varicella acuminata, verrucosa, during the period of suppu-
ration.
4. In muscular twitchings of a rheumatic origin, especially in the
limbs, which come on suddenly when at rest, and cease on motion.
5. In amblyopia with mists and flakes before the eyes, when it is at-
tended by symptoms which indicate Thuja.*
* May not Thuja be also specially indicated in chronic catarrh, in ozoena after
precipitate cures of gonorrhoea and condylomata, and in obstinate bronchial catarrhs.
— Ed. Oest. Zeit.
146 Thuja Occidentalis.
Those physicians who, with Lobethal and others, consider condylo-
mata as constantly and without exception a result of secondary syphilis,
and do not allow that they ever appear independently, must, conse-
quently, consider Thuja as one of the remedies for syphilis.
It cannot indeed be denied that the symptoms which Thuja develops
in the sexual, glandular, and cutaneous systems present similarities to
the phenomena of secondary syphilis ; but this drug has not produced
in a single prover ulcerative sickness and peculiar sores, as mercury ex-
cites them. We cannot, then, attribute to Thuja any special therapeutic
power in primary syphilis, and homoeopathic literature has as yet no
cases to show of chancre cured by its means.
Cures in cases of Animals.
' Homoeopathy proves itself true, not only in the cure of men, but
also in that of animals ; and she receives great commendation both from
cattle doctors and cattle owners, for the three virtues of simplicity, effec-
tiveness, and cheapness.
Physiological provings of Thuja on animals, are as yet wholly wanting ;
still this admirable remedy, from its property of exciting warts and cu-
taneous excrescences, has been used in analogous diseases in veterinary
medicine.
1. Horses. — The tincture of the arbor vita? has been used by veteri-
nary physicians with the best results in grease, which is related to syco-
sis in this, that if the disease be neglected, warty excrescences form in
the fetlock, which bleed easily, and, like condylomata, secrete an offen-
sive fluid (Dr. Elxvert, Hygea, B. 19, s. 415).
Thuja has also testified its power in the cure of warts in horses,
which arise in various spots, especially in the neighborhood of the ears,
eyes and nose, if these excrescences exhibit a rough, split, cauliflower-
like surface, and, like condylomata, bleed easily, are moist and suppu-
rating.
Oberamtmann Kleeman cured a horse, within three weeks, of warts,
which he had had for several years on the head and chaps, with a
few doses of Thuja 2 and 15 (Archiv fur. horn. Heilk. B. 14, H. 2
s. 108).
2. Cattle. — Warty excrescences often appear in great numbers, and
of various sizes, upon the udders of cows.
Thuja has been exhibited in case of these warts with success, when
it was indicated by their character.
According to Dr. Schindler, Thuja perfectly cured five very similar
cases of warts in cows, whose udders were entirely covered with the ex-
crescences (Archiv fur horn. Heilk. B. 14, H. 2, s. 108).
3. Bogs. — Dogs are not unfrequently affected with mulberry-like,
moist, easily bleeding warts, which sometimes cover the whole naked
Theory of the operation of Thuja. 147
inner surface of the ears, in the form of a cauliflower, or arise in the ca
vity of the mouth, and greatly resemble condylomata.
Dr. Wachtel observed the following case : a little, two months old,
male pup (wolf dog) got, without any known cause, near the anterior
border of the tongue, a fleshy excrescence of the size and shape of a hemp-
seed, which, in eight weeks increased to the size and form of a mulberry.
On the inner surface of the mouth also, fleshy cauliflower-like excres-
cences were visible, thickly sowed on both sides. He was sprightly, and
well, but took food and drink with difficulty.
From the striking similarity of these excrescences to condylomata,
Wachtel attempted to cure them with Thuja, and caused the whole of
the warts to be painted twice a day with the tincture.
During the first eight days no change could be perceived in the ex-
crescences, except that they grew no more. On the twelfth day, little
cracks showed themselves on their surfaces, which occasionally bled.
From the sixteenth day on, small pieces separated by degrees, dried,
and fell off. At the end of four weeks, his mouth was clean and every
trace of an excrescence was gone.
CHAPTER VII.
Essay toward a theory of the operation of Thuja.
Dr. Huber is the only one of the provers of Thuja who has commu-
nicated his views on the subject. They are verbatim as follows.
" The head, muscles of the nape, and the genitals were the points upon
which the force of Thuja was especially expended in me. It seems equally
to affect the systemic solids and fluids. It seems to create in the blood a
peculiar condition whereby it, through increased innervation, acquires the
disposition to excite the vitality of the reticular tissue (especially the sub-
cutaneous and intermuscular) in the form of increased warmth, congestion,
and swelling (inflammalio), and to form there products which appear in the
provings partly as excrescences (tubercles) and partly as suppurating exsu-
dations. Among the solids, it is the sensitive portion of the nervous system
the activity of which is increased by Thuja. The plexus cceliacus and hypo-
gastrics of the ganglionic system receive the first impression, which by
means of the sympathetic is reflected on one hand, upon the trigeminus,
and on the other, upon the sensitive nerves of the spinal marrow, especially
upon those of the neck and sexual organs (nervus pudendus communis).
But since these nerves are for the most part distributed to and ramify in the
subcutaneous and intermuscular reticular tissue, their increased activity
can only be considered as heightening the vitality of that portion of the or-
ganism. The sanguineous condition produced by Thuja seems to bear the
same proportion to the increased nervous influence as the disposition does
to the noxious cause (causa occasionalis). If then Thuja possesses the
power not only of changing the blood but also of increasing the vitality of
the nervous and reticular systems, why should it not be endowed with the
faculty of curing excrescences of various kinds, such as warts, condylomata,
148 Thuja Occidentals.
and other spurious growths* which are plainly founded upon conditions such
as those we have stated. The fundamental operation of Thuja therefore
appears to depend upon a peculiar condition of the blood, and on an excite-
ment of tlie vitality of the sensitive, nervous, and reticular systems."
We may be allowed to remark that a theory founded upon the results
of a single proving must necessarily be one-sided. It is only by means
of an association of provers that the whole sphere of operation of a
remed} 7 , in all its breadth and depth, can be developed, and the theory
of the operation of drugs must stand upon a statistical foundation. The
single prover develops only isolated portions of the full operative
sphere of the remedy.
The effects upon the sanguineous and nervous systems together, are
exhibited by every drug in common with Thuja, and you may have as
many " conditions of the blood " as you have drugs ; for every intoxi-
cation passes into the blood.
Our own view of the matter is this, that the general physiological
effect of Thuja is irritation of, and increase of, vitality in the system
of the tissues ; causing, in fibro-serous membranes, wandering arthritic
pains ; in ?nucous membranes (uro-genital apparatus and air passages,
Ed.), increased and altered secretion, and upon the external skin, warty
excrescences. The trigeminus, the jj/ctms cervicalis and pudendo-ho3-
morrhoidalis are especially attacked ; hence the most important speci-
fic symptoms of 'ihuja are developed in those provinces and organs
which are supplied by these nerves and their ramifications.
CHAPTER VIII.
Dose, Duration of Action, Allied Remedies, and Antidote.
Dose. — On this subject Hahnemann has recommended the 30th di-
lution as the highest dynamic potence, and the undiluted tincture as the
lowest material dose, so that here we have the most refined dynamism
and the grossest materialism standing in conjunction. The employment
of the high potencies is declared to be sufficient in simple cases of
recent origin, and that of the mother tincture to be necessary in severe
ones of long standing (though only in external applications). In this
extensive therapeutic scale we have, on the one hand, the proof that
Hahnemann had departed from his decreed normal dose of the decil-
lionth (of which fact many examples are to be found in the second
edition of the Materia Medica Pura), and on the other, the informa-
tion for those opponents of Homoeopathy who in some incomprehensible
manner, place its essence in the smallness of the doses instead of in the
principle of similarity, that cures performed with the tincture of a spe-
cific remedy are still homoeopathically wrought.
* Thuja cures warts, condylomata, and such spurious growths, for the simple
reason that it actually creates similar excrescences. — Mayrhoftr.
Dose and Duration of Action. 149
We repeat here what we have heretofore said in relation to posology
{Hygea B. 19, s. 215) : "The relation between irritability, and the size
of the dose, is different in different individuals, and in different diseases,
and the sliding scale of doses must go parallel with this varying
standard."
The individualisation of the quale and quantum of a drug must be
reciprocally regulated, and the practising physician must be permitted
the discretion of ascending or descending the therapeutic ladder, ac-
cording to the exigency of the special case in hand.
For the practical man, the sole effective cure of disease lies neither in
the seventh heaven of the high potencies,* nor in the lowest hell of the
mother tinctures, but the maxim, " medium tenuere beati" has its full
value here also.
According to our own experience, the first dilution of Thuja, (10: 90.)
corresponds to the larger part of patients and diseases ; still there are
subjects who manifest so much sensibility to the action of Thuja that
they tolerate only high and infrequent doses, while with torpid indivi-
duals and in neglected cases, the external and internal employment of
the tincture is frequently necessary for a considerable length of time.
Duration of Action. — The course of the Thuja sickness like that of all
other drug diseases, is partly of an acute and partly of a chronic sort.
Many of the symptoms, especially those of the prima? via?, which
come on immediately after the dose, disappear again in a short time.
The nervous affections and pains of Thuja extend over a longer period,
on account of their frequently recurring at irregular intervals of hours,
days, and weeks, and the objective products run a chronic course, some-
times of weeks and months, as the provings have shown. In this rela-
tion we must rank Thuja rather among the chronic remedies.
As to the repetition of the dose, we may here also rely upon the
maxim that, regularly, in acute diseases stronger and more frequent
doses are required, (repeated in from two to three hours,) and that in
chronic cases, higher and less frequent doses will answer (at intervals of
one, two or three days). Torpid subjects bear strong and repeated
doses, while erethic constitutions need but little medication.
Allied remedies. — The nearest neighbors of Thuja in reference to the
urinary organs are, Cannabis, Petroselinum, Copaiba-balsam, Cantha-
rides, Pulsatilla, and Mercury. Hemp is useful in acute gonorrhoeas,
with a thin, very copious discharge, and very painful urination. Par-
* Without wishing to dispute the possible efficaciousness of the so-called high po-
tencies, I wish merely to suggest the following doubts :
1 . The high potencies appear to possess virtue, only when they are freshly pre-
pared.
2. Their preservation must be watched over with the greatest caution and fear of
depotentising (two very uncertain particulars both for doctor and patient).
3. The high potencies carry the materia medica into the metaphysical region of
the world of shadows and of spirits, a most dangerous circumstance not only in re-
ference to our opponents, who believe nothing without proof from physics, but also
in reference to the science itself which has a solid foundation. — Mayrhofer.
150 Thuja Occidentalis.
sley is only serviceable in slight cases, with constant urgency to urinate,
and Copaiba corresponds to blermorrhoeas, whose chronic course is at-
tended by torpidity of the mucous membrane. Cantharides are indi-
cated in cases of decided inflammation of the urinary organs and hae-
maturia. Pulsatilla is indicated in gonorrhoeas characterised by the
passage of urine in drops, or by affections of the testicles. These re-
medies are effective and curative, especially in irritation of the urinary
apparatus, arising from rheumatic, mechanical, and chemical causes.
Our choice falls upon Mercury, when gonorrhoea is combined with
chancre.
Farther removed we have Acid, nit., Alum., Capsic, Cubebs., Nat.
mur., Petrol., Sab., Sepia., Sulph., which are especially indicated in
those gonorrhoeas which have become chronic or complicated with dys-
crasic and drug diseases, and must be selected according to the pecu-
liarities of the accompanying symptoms.
In blennorrhoeas, however, arising from contagion and accompanied
by condylomata, Thuja is, and remains the master remedy, as Mercury
is in urethral chancres. In sycotic conditions, Sabina and Lycopodium,
come next to Thuja ; Sabina frequently effects the cure of condylomata
alone, often completes it after Thuja, and these two remedies seem even
to take higher rank than Thuja, in cases of solitary, dry, whitish and
pedunculated condylomata. For the employment of Acid, nit, which
Hahnemann recommends in alternation with Thuja, in condylomata of
long standing, two grounds may be stated : 1, its physiological relation
to the urinary organs, and 2, its antidotal power to Mercury in gonor-
rhoeas and condylomata, which have been treated and maltreated with
Mercury in allopathic doses. Nitric acid is also, according to our expe-
rience, a very valuable remedy in urethral strictures, which are mani-
fested by spasmodic urination and vesical blennorrhcea. In the common
warts which appear upon the hand, the nearest allied remedies are Rhus
and Dulcamara. Further removed, Canst, in those which are inflamed
and painful, Lycop. in those which are pedunculated, and Calc. and
Sulph. in those which are accompanied by chronic eruptions.
Antidote. — Hahnemann gives Camph. as the antidote to Thuja,
which, with Coffee, stand, though not in antidotal yet in palliative re-
lation to the most of the vegetable remedies.
We know of no cases of poisoning by Thuja, and none happened in
the course of our provings, although some of the provers went great
lengths, among whom Prof. Zlatarovich stands distinguished as the
boldest Thujophagite. They would be mitigated by drinking warm
milk or mild oil.
To isolated manifestations of the Thuja sickness, several remedies are
antidotal. Cham, removes the nocturnal twitching toothache; Cocc.
appears to be serviceable in the acute fever of Thuja,* and Merc, to al-
leviate the affections which appear at night.
* See ZlatarovicVs provings of Thuja upon an adult female.
Gonorrhoea and Chancre. 151
The best antidote, however, is the administration of higher and less
frequent doses of the remedy, when it has excited excessive effects in
constitutions susceptible to the action of the drug.
APPENDIX.
Are Gonorrhoea and Chancre results of the same disease ?
Since the discovery of syphilis, more than three hundred years ago,
two thousand works have been written by physicians on these sin-born
scourges of the human race, and it might be thought that in this su-
perabundant wealth of the literature of syphilis all important questions
in relation to the subject treated of, would have been exhausted. But
it is not so. Not only is the veil which covers the origin of the disease
still unremoved, but the very weighty question whether gonorrhoea and
chancre are identical or different morbid processes, is as yet unsettled.
A few physicians and authors, as Bell, Autenrieth, Hitter, Haase,
and others, distinguished gonorrhoea from chancre as independent forms
of disease, which were, however, capable of existing together ; but the
greater number of the iEsculapian priesthood consider them as only two
varieties of the same disorder, syphilis. This floating controversy was
blown into a flame anew by Hahnemann's categorical assertion, that sy-
philis and sycosis are two entirely different miasmatic diseases; and that
spirit of contradiction which leads the old school, in order to affirm its
own existence, to deny everything that Hahnemann has said, fell also
with grim violence upon this tenet of the therapeutic reformer.
The old school, as the universally generalising system, holds to the
view that the blennorrhagic process of gonorrhoea and the ulcerative
process of chancre are only modifications of one and the same funda-
mental disease, syphilis ; while the new school, as the individualising
method, cannot agree to the identification of the two maladies.
The advocates of the identity theory found their belief upon the fol-
lowing grounds :
1. Gonorrhoea and chancre are communicated by means of a fixed
contagium.
2. They both frequently appear in the same subject and at the same
time.
3. According to Hunter and Harrison's experiments in inoculation,
the gonorrhceal discharge excites chancre, and chancrous pus produces
gonorrhoea.
4. Gonorrhoea and chancre differ only because of the different orga-
nisation of the tissue attacked. If the contagion falls upon the mucous
membrane of the Urethra, blennorrhcea virulenta {syphilitica) appears,
but if it fall upon the sexual parts, it is succeeded by ulceratio syphi-
litica.
152 Tlivja Occidentalis.
5. Gonorhcea is the milder, chancre the more virulent form of sy-
philis.
6. Constitutional symptoms may follow simple gonorrhoea as well as
•chancre.
7. Among several persons who have received the contagion from
one and the same individual, some will have gonorrhoea, and some
chancre.
The defenders of the essential distinction between gonorrhoea and
•chancre rely upon historic, nosographic, and therapeutic grounds.
1. On the first appearance of syphilis in Italy, in 1494, contagious
gonorrhoea [blennorrhoea virulenta) was still entirely unknown. The
writers on syphilis during the first decennia do not describe the urethral
discharge ; even Vigo, who had spent ten years on his work upon syphi-
lis, was not then acquainted with gonorrhoea. Blennorrhoea urethrce
virulenta was first observed and described by the physician Antonius
Musa Brassavolus, thirty-nine years after the eruption of chancre, and
his pupil Gabriel Follopius affirms, in his work (De morbo Gal. Pa-
tavii, 1563), that the urethral discharge was a more recent disease than
syphilis, and had been entirely unknown before it was observed and des-
cribed by his master.
2. Hahnemann states (Chron. Krank. 2. Auf. B. 1, s. 104) that sy-
cosis, under which appellation he includes not only condylomata with and
without gonorrhoea, but also the contagious, virulent, urethral discharge
without the so-called excrescences, has only raged from time to time, and
was extensively disseminated as an epidemic, especially during the
French war from 1809 to 1814 ; since which, however, it has continued
to manifest itself less and less frequently.
3. Hunter and Harrison's trivial experiments have not only not been
confirmed on a more careful repetition, but have been wholly refuted by
the numerous and standard experiments of Ricord in inoculating with
pus from gonorrhoea and from chancre. No chancre pustule is excited
by inoculation with gonorrhoeal pus either on the external skin nor on
the mucous membrane ; while chancre causes chancre both upon the
external skin and mucous membrane. Inoculation was so performed
upon a patient who had both gonorrhoeal and primary chancre, that one
thigh received the gonorrhceal virus and the other the chancrous ;
the last only developed a chancre pustule, the other did not. — (See
Ricord.)
4. If chancrous matter could develop gonorrhoea, and gonorrhaoel
virus, chancre, gonorrhoea and chancre should almost always appear to-
gether, for in blennorrhoea virulenta the glans and prepuce (the com-
mon situations of chancre in man) must necessarily be fouled with the
discharge, and in the same manner the pus from a chancre must inevita-
bly be brought in contact with the mucous membrane, especially in wo-
men. Besides, from pretended observations that gonorrhoea has caused
chancre by infection, and chancre in another subject gonorrhoea we can-
not exclude the possibility of deception : because urethral chancre may
Gonorrhoea and Chancre. 153
be easily mistaken for gonorrhoea, and give rise to false observations,
while in fact the chancre has only given rise to its like.
5. Chancre and gonorrhoea depend upon pathological conditions
which are altogether diverse. Chancre is an ulcerative process, healing
with loss of substance ; gonorrhoea is a blennorrhagic process, heeling
without destruction or loss of organic matter.
6. Both the acute and chronic sequelae of gonorrhoea and chancre are
different — The suppression of acute gonorrhoea excites again acute
forms ; as, epididymitis, cystitis gonorrhoica, ophthalmia blennorr-
hoica, and, according to Bitter, synocha cum deliriis furibundis. But
on the premature destruction of the primary chancre the symptoms of
secondary syphilis make their appearance.
7. Syphilis affects exclusively the human race, while sycosis under
various forms appears likewise in animals.
8. The most effectual though not sole specific against chancre is mer-
cury, while in gonorrhoea it is far surpassed in efficiency by other reme-
dies, which fact does not agree with Hufeland's view [Enchiridion Aufl.
5, s. 495), who lays it down that the gonorrhoea! and chancrous virus
are products of the one syphilitic contagion, but that the blennorrhagic
infection is the milder of the two ; for we cannot understand how a re-
medy, which is powerful enough to subdue the more deadly virus,
should be too weak for the milder form of the same poison. That dis-
tinguished authority upon syphilis, Louvrier, states as follows, in his
monograph on that disease (page 51), "Mercurial remedies, in whatever
form they may be administered, *are useless and injurious in simple go-
norrhoea ; useless, because gonorrhcea is not a (general) venereal disease,
and experience has shown that that disease, when combined with go-
norrhoea, has been cured with mercury, but that the gonorrhoea still
continued after the cure ; injurious, because by the administration of
mercury increased disease of the affected parts, in the form of renewed
inflammation and interruption of the gonorrhceal discharge, is not un-
frequently produced."
" As to condylomata, which have appeared after gonorrhoea, the pa-
tient may be salivated into marasmus, and there they will remain un-
changed ; but should they have succeeded to chancre, they readily
vanish under the ordinary mercurial treatment. This is a truth, of
which every physician, experienced in the treatment of this disease, is
well aware, and which I have a hundred times found confirmed in my
practice. We should therefore minutely inquire whether gonorrhcea or
chancre has been the predecessor of the condylomata." *
9. The chronic sequelae of gonorrhoea are essentially different from
the symptoms of secondary syphilis.
Ritter describes them under the name of lingering gonorrhoea, and
divides it into three degrees or stages.
* This categorical opinion of Louvrier leaves no room for doubt but that two dif-
ferent diseases may lie at the foundation of condylomata. — Mayrhofer.
154 Thuja Occidentalis.
First Stage. — This is characterised by itching on the hairy portions
of the genitals, which, by degrees, becomes intolerable, is most violent
in the evening and night, is increased by warmth and covering, and
irresistibly compels the patient to scratch. As the itching diminishes,
an itching sticking comes on in isolated circumscribed spots on the
genitals, and after scratching, numerous moist points appear about the
roots of the hair, which change in from twelve to twenty-four hours
into dark brown or black scabs and easily fall off. This scene is re-
enacted almost every day. Similar points even appear on the border
of the navel with itching; later they make their appearance also on the"
perinseum and on the thighs, in the neighborhood of the sexual organs.
In the female sex, the pain of the tormenting itching is greater and the
discharge of lymph more considerable. The hairs themselves are not
painful either upon the head or upon the genitals, and the alopecia pe-
culiar to chancre never follows.
At the same time or later pear-shaped warts appear on the female
patients, which occasionally itch, and when excised immediately return.
Men most commonly do not exhibit these warts ; but yellowish-white
shining grains of the size of fine barley appear upon the scrotum, which
do not itch, but disappear again unnoticed.
After some weeks or months an elastic tubercle appears upon the
inner side of the inner lip exactly over the labial artery, under which
the artery pulsates briskly every evening. Sometimes a spot appears
on the under lip which looks inflamed, burns somewhat, and shows the
bluish white epithelium in some cracks ; this scales off in three or four
days, and is immediately replaced by another. This symptom is fre-
quently repeated at intervals of weeks or months, always in the same
way. The urethra, so far as the eye can reach, is affected with whitish
spots, which are but little painful, have here and there a depression,
feel somewhat callous, and show the mucous membrane still unaffected.
Similar spots appear in the female sex in various parts of the internal
sexual organs.
Second Stage. — After a certain time, pressing in one or more of the
articular extremities of different bones comes on in the evening, until
the patient goes to sleep, which may be absent again for days, weeks,
and months. The bones most frequently attacked are the sternal ex-
tremities of the clavicles, the end of the radius, the ribs, and the tibia.
The periosteum is inflamed, and the painful spots are swollen ; but the
pains never appear in the middle of the hollow bones. Copious, deep-
seated, hardish tubercles are perceptible to the touch on the inner sur-
face of the lips and cheeks, and afterward in the soft palate. A partic-
ularly painful spot appears from time to time in the concha of one of
the ears, or a slight inflammation is developed in the external ear. Per-
manent little erosions of a whitish blue tint form upon the lips or cheeks,
sometimes on the tongue and palate, and the epidermis repeatedly scales
off from various spots on the scalp. Cracks and fissures (JRkagades)
arise in the soles of the feet, oftener in the palms of the hands, which
Hitter's Picture of Gonorrhoea. 155
are for the most part dry, less frequently moist, and a transverse crack of
an inch in length frequently forms in the neck opposite the atlantic ar-
ticulation, which discharges, and commonly closes spontaneously. Iso-
lated, dark red, inflammatory spots, of the size of a pea, hard to the
touch, come to light upon the breast, back, shoulders, arms, and thighs,
and occasionally in the conchse ; they suppurate at the point, and leave
behind elevated dark-red nodosities upon the skin which only disappear
after months. Small reddish-brown spots appear likewise upon the
elbow-joint, remain a few days, then suddenly disappear, and frequently
return in the course of the disease. During this time the spots already
alluded to in the urethra become gradually larger, their callosity in-
creases, the depressions enlarge by the circumference, and erosions ap-
pear, which however result in very slight loss of substance. In fact,
pus or offensive fluid is not secreted from these points ; they are most
frequently dry, or covered with a moisture which rather resembles
healthy mucus than a morbid secretion.
These superficial erosions have been improperly called primary go-
norrhoeal ulcers. Sensibility is rather diminished than increased in
these affected spots ; urination is neither difficult nor painful ; only
toward evening or after coitus a very unpleasant pressing manifests it-
self in the urethra. At the same time or later than these mostly chro-
nic erosions in the urethra, similar, entirely painless erosions are observed
upon the lips and cheeks, seldom in the nostrils, the color of which
borders rather upon blue than white. These may last a long while
without sensibly increasing in size, and they never corrode deeply with
any material loss of substance.
A periodical itching of the scalp, obliging the patient to scratch, is
also often perceived, and a thick moisture exudes and forms little crusts,
which after a few days fall off. The herpetic eruptions which are added,
though not always, to the already described symptoms, are more consi-
derable and more troublesome ; they may appear on various parts of
the body, but principally affect the dorsa of the hands. This herpes
surpasses all the other symptoms of this disease in obstinacy, and in
spite of every remedy has been observed in a patient for thirty years.
It is almost always dry, seldom causes violent itching, frequently re-
moves the epidermis and never forms scales.
The general health is still but little affected, all the vital functions are
normally performed, and the glandular system is not perceptibly sym-
pathetically affected.
The chronic gonorrhoea now under consideration never appears with-
out erosions in the urethra, and the urethral callosities, strictures, carun-
cles and fistulas, which frequently arise as sequelae of chronic, neglected
or maltreated gonorrhoea, only so far belong to the lingering gonorrhoea
as they are accompanied by its other symptoms. The eyes and lungs
are occasionally affected in the subsequent course of the disease. The
symptoms of the eyes are commonly like those of a chronic rheumatic
ophthalmia, and the affection of the lungs resembles a neglected catarrh.
156 Thuja Occidmtalis.
Sometimes the knee swells and becomes stiff and painful.* All these
symptoms may continue for years, and creep on with a scarcely observ-
able progress for the worse until the disease in a few cases reaches its
highest development.
Third Stage. — This is distinguished by the formation of spurious
products, preceded in the commencement by pains which indicate a
mechanical compression in the abdomen. These spurious growths are
tallowy concretions, whitish or yellowish in color, sometimes of a harder,
sometimes of a softer jelly-like consistence, are enveloped in membranes,
and when they lie superficially, sometimes pass into suppuration. They
are sometimes situated externally on the neck or chest, sometimes inter-
nally, where they may appear in any of the intestines, e. g., in the omen-
tum and mesentery, in the liver and pancreas, in the lungs and kidneys,
&c, and in the female sex frequently in the ovaries. Occasionally only
isolated or a few large growths are found in the abdomen or in the
neighborhood of the clavicles.
The grouped parasites which are frequently arranged like a rosary,
are from the size of a pea, to that of an egg, when they resemble a
potato tubercle. The solitary ones may attain an enormous size. In
the female sex, a round elastic swelling sometimes appears in the uterine
region, which finally bursts (by a violent commotion) and discharges its
purulent contents through the vagina, but fills again by degrees, and
again, at the proper time, discharges.f The menstrual function is irre-
gularly performed, and a mild, moderate leucorrhcea appears from time
to time.
With the appearance of the tallowy concretions (Steatomata), the
patient becomes ill-humored and indifferent to every thing which had
formerly given him pleasure ; he seeks solitude ; his face assumes a
hectic appearance ; his sleep departs, and lingering fever, dreadful pros-
tration, and death, close the scene. Less frequently the disease simulates
the form of an angina pectoris. The patient at first feels oppression of
the chest, then attacks of pain when walking, and cramps in the chest
at midnight, which end with syncope. All the functions fall into dis-
order, and he dies in one of the nocturnal asthmatic attacks, and the
autopsy shows the spurious growth already described.
Such are the essential characteristic marks attributed by Batter to the
chronic gonorrhoea, which he made the object of his especial researches
for five and thirty years. They led him to the painful conclusion that
this disease, considered identical with syphilis, was incurable, and that
* This elastic swelling of the knee is called by the English " white swelling.'' 1
Many physicians consider this articular rheumatism as a consequence of the admi-
nistration of balsam of copaiba for gonorrhoea, but Cumano (Syphilid. B. 5, s. 461)
considers it as a metastasis entirely analogous to a gonorrhoea! ophthalmia. — Mayr-
hofer.
1 1 have known a similar case myself. — Mayrhofer.
Hahnemann on Sycosis. 157
its course, though long and lingering, was not to be stayed.* (See
Ritter's exposition of the apparent similarity, and essential difference,
between chancre and gonorrhoea, Leipz. 1819.)
We annex to this lengthened description of Ritter's, the short and
comprehensive account of Hahnemann.
Sycosis, which lately, especially during the French war, from 1809 to
1814, was widely spread, but has since showed itself continually on the
decrease, was almost always fruitlessly and injuriously treated, by the in-
ternal use of mercury (because it was thought to be identical with the
venereal chancre) ; the excrescences on the genital parts, on the contrary,
which commonly, though not always, appear several days, or perhaps
some and even many weeks, after contagion received by coitus, under a
discharge of a sort of gonorrhoea from the urethra, seldom dry and
warty, more frequently soft, fungous, and distilling a peculiar, sweetish
moisture almost as offensive as herring pickle, bleeding easily, having
the shape of a cockscomb or cauliflower, in man upon the glans, or on
or under the prepuce, but in woman occupying the neighborhood of
the pudenda, and even the pudenda themselves in great number, have
been, until now, destroyed by allopathic physicians, by the most vio-
lent external treatment, by cauterising, burning, excising, or the ligature.
The natural consequence of this was, that they generally returned, or if
they suffered themselves to be thus annihilated, the sycotic affection
being deprived of the vicarious local symptom of the internal evil, now
appeared after another and worse manner, in secondary affections. Thus
neither by the external destruction of the excrescences, nor by the inter-
nal use of a remedy not indicated, mercury, was the miasm in the least
diminished in its control over the whole organism. Besides the under-
mining of the general health by means of the noxious use of mercury,
generally administered in the largest doses, and in the most virulent pre-
parations, similar excrescences break out on other parts of the body,
either whitish fungous, sensitive, fiat elevations in the cavity of the
mouth, on the tongue, palate, and lips, or large, elevated, brown, dry tu-
bercles in the axillae, external neck, scalp, etc., — or, otherwise, other bo-
dily sufferings come on, of which I will only mention, the contraction of
the flexor tendons, especially of the fingers. (Chron. Krank., 2. Auji.
B. 1, s. 104, 105.)
* We give this descriptive portrait of gonorrhoea, with the remark that the co-
pious symptoms are brought together from the observation of many different
cases, and that in individual patients only individual parts of the description will be
applicable — according to the proverb, " non omnia adsunt in omnibus." Single
cases of the form of disease here described with such accuracy, have undoubtedly
occurred to every practitioner, and we recommend to the further examination and
impartial investigation of our colleagues, this, in our opinion, most important matter.
We ourselves, in fault of sufficiently extensive experience, can form no decided opi-
nion whether the chronic disease, described by Ritter, is the natural and necessary
consequence of an uncured gonorrhoea, or a variety of blennorrhoea, caused by a
vitiated state of the blood, or, still further, a combination of sycosis and hydrargy-
rosis, consequent upon mercurial treatment. — Mayrhofer.
158 Tfmja Occidentalis.
We add now, to complete the triad, Autenrieth's communication on
scrofulous gonorrhoea {Tubingen Blatter B. I. H. 2, s. 187, et seq.\
which confirms Ritter's observations on the spurious growths standing
in causal connection with gonorrhoea.
Autenrieth describes with accuracy the spurious organisations referred
to, without its having been possible for him to have known of Ritter's
experience, and his remarks upon the sequelae of gonorrhoea agree with
Ritter's description.
"Gonorrhoea has the peculiar property of producing only one local
disease at a time ; if this cease, immediately another local affection ap-
pears in another place. In men, ^arcocele often appears; in women, de-
generation of ihe ovaries. Gonorrhoea is nearer allied to lepra than to
syphilis. The peculiar superficial ulcers of gonorrhoea, with a cancerous
appearance, secrete only a wateiy fluid ; and the gonorrhceal poison is
in itself incurable, and can only be excreted by nature as long as it is a
local disease.*
We have thus extracted and brought together the points of agree-
ment and difference between gonorrhoea and chancre from competent
authorities, without expressing a decided opinion upon the question
ourselves, in consequence of a deficiency in our private experience. As
things stand at present, however we by no means hold the contro-
versy as ripe for judgment, but are convinced that this weighty question
will only then receive its scientific solution, to the relief of suffering hu-
manity, through the individualising therapeutics of Homoeopathy, in
connection with the revelations of pathological anatomy, when oppor-
tunity shall be afforded to emancipated Homoeopathy to make decisive
investigations on the subject by the aid of syphilitic cliniques.
In reference to the treatment of gonorrhoea, we can neither admit
the absolute incurableness of the malady with Autenrieth and Ritter
(allopathically), nor its ■ absolute curability with Hahnemann (homoeo-
pathically).
In choosing a specific remedy, two considerations must be borne in
mind; 1, the most accurate estimation of the entire symptoms of the
disease ; 2, the minutest examination of the history of the disease in re-
ference to the origin of the affection, its previous treatment, and the at
present existing dyscrasic complications.
Thuja is the chief remedy in sycotic cases, in alternation with nitric
acid, where mercurial treatment has been resorted to. Obstinate tetters
indicate Nat. mur. and Lycop ; if itch have preceded, Sulph. and
Hepar. ; disgust of life points to Aur. ; scrotal herpes to Rhus, and
Arsen. A radical cure, in fine, is only to be obtained from a so-called
antipsoric treatment, conducted with the closest individualisation of the
malady of the patient and of the remedies prescribed.
- * Compare, on this subject, the ideas of Eisenmann, Schdnlein, Timon and
Jahn in the Vet such, fur die prakt. Heilk. (Eisen. 1835, s. 84-107.) " Bemer-
kungen uber die Tripperseuche' 1 '' of the latter. — Ed. ffisf. Zeit.
159
2.— ^ETHUSA-CYNAPIUM.
^ETHUS. Fool's parsley. Fr. Petite cigue, faux persil, cigue' des
marais. Ger. Hundspetersilie.
1. Description and Preparation.
This remedy belongs to the order Umbelliferce. It is a little annual
plant, growing in this country in waste places and by roadsides, from
one to two feet high, and much resembling common parsley. Many
dangerous accidents have been caused by the similarity. From a taper,
whitish root arises an erect branching stem generally stained with purple
near the ground, but free from the spots of the Conium, and covered
with finely cut leaves of a deep glossy green. The whole plant emits a
nauseous odor and is very poisonous. The leaves are bi-triternately
compound ; the ultimate lobes or segments linear-lanceolate ; umbels
terminal and opposite the leaves, rays veiy unequal ; leaflets of the invo-
lucels linear, all on one side ; fruit very prominently ribbed and keeled.
The expressed juice of the fresh plant at the time of flowering is used
in medicine.
2. Prior knowledge of its effects.
Dr. Roth makes the following notes on this subject.
The old school has never made use of this plant as a remedy ; it
figures only in toxicology, and the accounts given of its effects previous
to the eighteenth century are of no service, as it was frequently con-
founded with conium-maculatum and cicuta-virosa. For this reason
I have made no use of Gmelin's citations (Hist, venenor. vegetal) kuevia
indig. Nova acta physico-medic. 6, 259). The cases related by the
following authorities contain nothing of interest : Boerhaave {Acta
reg. Loc. hafn. med. 1, 54) ; Blair (Pharmacobotanologia, Lond.
1, 725, p. 122); Schreber (Sammt. versch. Schrift.4, 273). Except
Kallenbach 's note cited among the authorities subsequently, no other
account of the use of the plant has been published. My own unpublished
case is the cure of a scrophulous ophthalmia in a young girl of eighteen.
The symptoms are incorporated in the symptomatology. Kallenbach
used the sixth dilution. I used the same in a hundred and twenty
grammes of vehicle, a spoonful every day for six weeks, without the
intervention of any other remedy.
160 JEthusa Cynapium.
3. Digest of the Symptoms.
The following symptomatology is taken from Dr. Roth's Materia
Medic. 1, 169. He cites the following
AUTHORITIES. 1, Muller, Ephemerid. natur. curios, cent. 10,
observ. 52, p. 369. 2. Trew, Commerc. litterar. norimberg. 1*731, p.
178. 3> Riviere, Mist, de VAcad. roy. des Sciences de Montpellier,
1766, 1, 170. 4, M. V. Bullet, de Pharm. 6 annee, no 8, p. 339.
5. Rust, Magazin fur die gesammte Heilk. 21, 248. 6. Hartlaub,
Praktische Mittheil, 1828, p. 13. 7. Nenning, ibid. 8. Wittke,
Huftl. Journ. 69, 122. 9. Mayer, Neue Bresslauer Samml. 1, 178.
10. Lalle, Bulletin de Ferrusac, 21, 308. H, Petroz, Bull, de la
Soc. horn, de Paris, 4, 337. 12. Trinks, Annal. der horn. Kim., 4, 1 1 2.
13. Kallenbach, Gaz. horn., de Paris, 18o0, no. 9. 14. Gkiesselich,
Uygea, 23, 255. 15. Roth, Unpublished Cases.
The pathogenetic symptoms are in roman letters ; the toxicological in italics, the
curative are denoted by a cypher (o), and the other figures in parentheses refer
to the above names.
MIND. Moral. Great flow of spirits (6). Flow of spirits, loqua-
city, facetiousness (11). Gay. in a good humor, in the forenoon; sad
and anxious in the afternoon (7). Excess of moral susceptibility (II).
5. Very great nervous susceptibility lasting a long while (4).
Sadness when alone (11). The disposition becomes retiring, weeping
as in nostalgia (11) Cross and ill-tempered in the afternoon (7).
Disposition to impetuousness (11). 10. Uneasiness, discontent even to
grief. Menial. Difficulty in fixing his attention (11). Slowness or
instability of his ideas, even to absence of thougbt (11). °Halluci-
nations. Delirium ; he thinks he sees dogs and ca.ts (2). 15. Deli-
rium ; he jumps out of the window (1). Stupor (5). Loss of
consciousness or a kind of stupefaction as though soiiu thing intervened
between the organs of sense and exterior objects (11). Stretched out
without consciousness (8, 9).
HEAD. Headachr. Cephalalgia (3, 5). 20. Pains in the head
and stupefaction (3). Throbbing in the head (11). Lancinations and
throbbing in the whole head (7). Sensation in the head, as if it were
broken (7). Tearing pain in the head (11). 25. Confusion in the
head as tnough the brain were compressed (7). Confused head during
the coiyza(Ll). Stupefaction ; he cannot remain tip (3). Feeling
of tension in the head (11). Vertigo (5), 30. Veitigo in the open
air (11 '. Vertigo when seated ; increased by making H n effort to quit
the seat (11). The vertigo comes on more especially towards the
middle of the day (11). The head pains are periodic, often co-exist
with paleness of the face, trembling in the jaws, pains in the pra-cordial
region (11). The head pains are especially felt on waking; they are
readily renewed by a chill ; they are diminished by he emission of
flatus and cease on g< ing to sleep (11). Ihmicraira. 35. Tearings
and tliiobl)ings in the right half of the head, then lancinations in the
JElhusa Cyncvpium. 161
left (7). Very painful lancinations and drawings in the left side of
the head (7). Twitching in the left half of the head, then
lancinations below the left nipple (in a woman), especially painful during
an inspiration (7). FrOlltaK Pains in the sinciput (9). Violent
pains in the sinciput as though it were forcibly compressed at the same
time behind and on the vertex (12). 40. Lancinations in the forehead
when turning the head to the right (7). Tension above the root of the
nose (11). Tearing pain across the eyes (11). Pain in the eye-
brows (11). Parietal. Lancinations and throbbings in the right
parietal bone (7). Vertex. 45. Pain in the vertex (11). Dull
pain in the vertex (7) Lancinations and painful throbbings in the
vertex, which disappear by rubbing (7). Temporal. A rapid tearing
thrust in the right temple (7). Lancinations, then throbbings, in the
upper part of the left temporal region (7). 50. Lancinations and violent
throbbings in the left temple, disappearing on pressure, but returning as
soon as the pressure is removed (7). A lancinating blow in the left
temple, then drawings towards the sinciput (7). Occipital. Lanci-
nations and throbbings in the upper part of the right occipital bone (7).
Rheumatic (tearing) lancination from the occiput forwards (7). A
tearing shock which passes across the whole head from the left side of
the occiput to the right side of the head (7). Scalp. 55. Feeling
of contraction of the hairy scalp (11). Inclination of the head to fall
backwards (11).
EVES. Lancinations around the eyes and in the orbits (11).
Excoriating pain around the eyes (11). Excoriating pain in the eye-
lids (11) 60. Uncomfortable sensation around the lids (11). Swelling
of the Meibomian glands ; gum in the. eyes (11) "Scrofulous ophthal-
mia (15). °Swelling of the Meibomian glands (15). "Chronic inflam-
mation of the edges of the lids (11). 65. °The edges of the lids are
glued together in the morning by a dried matter, which must be softened
to prevent its tearing out tlie lashes (15). Itching in the corners of the
eyes (11). Pressure on the eyes (11). Spasm of the eyes (11).
Distension of the eyes (11). 70. Brilliant injected eyes (9). "Pustule
upon the cornea (11). Pupils much dilated and insensible to light (8).
"Incipient amaurosis (11) Pupils dilated, but sensible to light (9).
75. Things look larger and sometimes double (11). Fixed look (8, 9).
"Chronic photophobia (15) The symptoms of the eyes .come on
mostly on waking and in the open air (ll).
EARS Lancinating pain behind the ears (11) £0. Sensation of
heat escaping from th-i ear (11). Dryness of the ear ; deficiency of
cerumen (11). Puriform discharge from the ear (11). "Yellowish
discharge from the right ear (14) Troublesome hissing in the ears
(ll). 85. Lancinating pain in the ears, from within outwards (11).
Lancinations in the right ear from without inwards (fi). Lancinations
in the right ear disappearing on introducing the finger into the meatus (7).
Lancinations in the 1 ft ear, with fe ling as if something warm were
issuing; these lancinations alternate with an analogous lancinating pain
in the left costal region (7). Lancinations in the left ear, followed by a
162 JEthusa Cyna/pium.
slight tearing around the ear extending to the vertex (7). 90. Pain,
at times lancinating, at times tearing in the right ear, which is only
slightly relieved by rubbing (7). Touch and pressure ameliorate many
of the symptoms of the ear (11).
NOSE. Feeling of pressure on the nose (11). Lancinations on
the left side of the nose, then burning pricking on the right side ; after-
terwards, pricking as if from a hot needle on the exterior of the scrobi-
culus (V). ° Herpetic eruption on the end of the nose (11). 95. Lan-
cination and drawing in the left zygoma ; then titillation in the left
upper teeth ; afterwards violent lancination in the left ear (7). Insipid
taste of coryza (11).
FACE. Drawing, tearing pains in the face (11). Transient heat
in the face (11). Cold sweat on the face (11). 100. Sweat on the
face (11). Pale face (8). Wan, red face (9). The countenance
looks fatigued (11). Expression of anguish on the countenance (11).
105. The features express great anguish and acute pains (9). Puff-
ing of the face during the menses (11). The face periodically puffed
and spotted with red (5). °Puffed face, speckled with red spots (15).
Little vesicles on the skin of the face (11).
MOUTH. Lips. 110. Yellowish spot on the upper lip (11).
Crack in the upper lip (11). Tearing in the lower lip extending into
the corresponding tooth (which?) (7). Twitching of the muscles
around the mouth (11). Sensation of cold on the chin and at the
commissure of the lips (11). JaWS. 115. Tearings in the lower jaw
when standing up (7). Pain in the submaxillary glands (11). Teeth.
Gnawing sensation in the lower teeth (11). Sort of shocks in the
lower teeth (11). Cavity. Buccal cavity dry (9). 120. Aphthae in
the mouth (11). Saliva* Flow of saliva as cojrious as though she
had been mercurialised ; it lasted fourteen days (4). Tongue.
Feeling as if the tongue were too long (11). Moist tongue (9).
Palate and throat. Lancinating pain in the arch of the palate (11).
Aphtha; and pustules in the throat, which render the state of the patient
almost desperate (11). 125- Itching in the throat, scraping (11).
Redness of the throat (11). Redness and swelling of the velum palati
and the neighboring parts ; inconvenience so as to threaten suffocation
(11). Heat in the throat (11).
APPETITE. Bitter taste (9). 130. Taste of cheese in the mouth
(11). Salt taste of food (11). Oniony taste (11). Taste difficult to
define; it exists before as well as after a meal (11). Want of appetite
although the tongue is clean (11). Want of appetite in the evening
(11). Want of appetite (5). Burning thirst (4, 9).
STOMACH. Eructations. Nausea with depression (11). Eruc-
tations of air (7). 140. Regurgitations which have the taste of the
ingesta (7, 11). ""Regurgitation of food an hour after the meal (15).
Eructations after having drunk (11). Difficult eructations (11). The
eructations are ameliorated on lying down (11). Vomiting. 145.
Violent vomitings of frothy matter, as white as milk (8). Vomiting
after the administration of milk (8). intolerance of milk ; children
JEthusa Cynajpiv/m. 163
return the milk almost as soon as it reaches the stomach, coagulated or
not, in the course of ten or fifteen minutes, by a sudden and violent fit
of vomiting ; they then sink for some minutes, in consequence of weak-
ness, into a drowsy state (13). Vomiting of greenish matter (11).
Copious greenish vomiting (5). 150. Vomitings and diarrhoea (3).
Vomiting and diarrhoea of greenish mucosity (9). Vomiting and
diarrhoea of mucosity tinged with blood (9). Vomiting and fever
(3). Vomiting with chill, sweat and weakness (11). SlOIliach. 155.
Painful sensitiveness of the epigastric region (11). Very violent pains
in the stomach (2). Painful contraction in the stomach (11). Sensa-
tion in the stomach as if something were inverted ; then feeling of
burning which ascends into the chest (7). Tearing pains in the
stomach extending into the oesophagus (9).
ABDOMEN. 160. Throbbing in the abdomen (11). Sensation of
digging in the abdomen (11). Abdomen tight and tense (4). Abdo-
men inflated, sensitive, especially in the region of the liver (9). Swel-
ling of the abdomen (2). 165. °Abdomen large, inflated (15). Colic
pains and diarrhoea (9). Hypochondria. Painful sensitiveness of
the hypochondria (11). Lancinations in the right hypochondria and
then in the right ear (7). A lancinating thrust in the left hypochon-
drium, behind ; then lancinations in the depth of the left mamma (7).
170. Continual lancinations in the left hypochondrium with burning, only
disappearing, except for a little while, by rubbing (7). Lancinations in
the region of the left hypochondrium, which frequently return and are
persistent (7). Umbilicus. Bubbling as of boiling water in the um-
bilical region, followed by gripings in the stomach (7). Colic pains
about the navel, followed by two soft stools in the morning after hav-
ing risen (7).
ANUS AND STOOLS. Anus. Contraction of the rectum (11).
175. Sensation of dryness at the anus (11). Feeling of excoriation in
the piles (11). Swelling of the hemorrhoids (11). Bleeding he-
morrhoids (11). StOOl. Constipation (11). 180. °Constipation (14).
Stools, consisting of matters imperfectly digested, a short time after a
meal or at night (11). Normal stool in the afternoon (7).
URINARY ORGANS. Cutting pain in the bladder (11). Urine.
Frequent call to urinate (11). 185. Frequent call to urinate in the
night (11). Copious discharge of urine (11). Urine red, discharged
with difficulty (11). The urine deposits a white sediment (11).
GENITAL. Lancinating pains in the (female) sexual parts (11).
190. Itching in the (female) sexual parts (11). Eruption of pimples
upon the (female) sexual parts (11). The menstrual blood is watery
(11).
RESPIRATORY ORGANS. Nasal Passages. Coryza in the
morning (11). Coryza in the open air (11). 195. Coryza, secretion
viscid (11). °Nose stopped by very thick mucus (15). Abortive
desire of sneezing (11). A single sneeze in the afternoon (!?) (7).
Speech almost prevented (11). 200. Slow speech (11). Respiration.
Hoarse respiration (11). Hissing respiration (11). Hoarse and hissing
164 yEthusa Cynapium.
respiration, especially when lying on the back (11). Unobstructed
respiration (9). 205. Painful, anxious respiration (5) Very
difficult respiration (l). The respiration is very painful and short
(2). Great oppression; she breathes with difficulty (4). Colli;!).
Slight cough (11). 210. Several paroxysms of dry cough in the after-
noon (7). Cough with sensation of tickling in the throat (11). Cough
with tearing pain in the chest (11). Cough with stunning pain in the
head (H). Cough increased when lying down (1 1). 215. Cough fol-
lowed by mucous expectoration (11). Cough with paleness of the
face (11). Cough with sweetish taste in the throat (1 1).
CHEST. Feeling of pressure as though the chest were encircled by
a band (H). Lancinations in the left side of the chest (o). 220. A
lancinating thrust on the right costal region (7). An acute lancinating
thrust in the middle of the chest ; then burning in the same spot, so
violent that she thinks she shall die, disappearing on external pressure,
and returning after (7). Heart. Violent palpitations of the heart
(4). Palpitations which are felt in the head (H). Palpitations with
vertigo, headache, agitation (11.) Breasts. 225. Swelling of the
mammary glands (11). Isolated pain in the mammary glands (14).
Acute, smarting pain with heat and redness of the breast, (from ex-
ternal application) ; a multitude of phlyctenm, vesicles filed with
lymph, appear on the breasts the next day and discharge a good deal
of serous fluid on removing the covering (4).
BACK. Neck. °Swelling of the lymphatic glands of the neck in
the form of a string of beads (15). Swelling of the cervical glands
(1 1). Nape. 230. Lancinating stitches in the nape (7). An acute
lancinating thrust in the left cervical muscles ; then throbbing over the
whole body, but particularly on the right side and behind, with feeling
of weight (7). Dorsal. An acute, lancinating thrust between the
scapulae (7). Feeling of weakness in the back (1 1). Drawing in the
back (11). 235. Sensation of heat in the back (7). Lumbar. Burn-
ing as though from a hot needle, first in the left lumbar region, then in
the right hypochondrium (7). Lancinations, like pricks, first in the
right, then in the left lumbar region (7). A lancinating thrust in the
right lumbar region, then sensation of slight pressure (7). Drawings in
the left lumbar region when walking, disappearing when seated (7).
Sacrum. 240. Burning on the exterior of the sacrum, disappearing
on rubbing (7). Feeling of weakness as if paralytic in the sacrum
when rising from or turning in the bed, during the motion (11).
Stinging as if from a flea on the sacrum (7). Sensation of constriction
as though from a screw in the sacrum (7). Hips. Griping on the
exterior of the right hip (7). 245. Tension in the right hip, then
tearing lancinations in the right ear (7). Lancinations and drawings,
extending from the left hip into the thigh (7.)
EXTREMITIES. Cold extremities (3, 8).
UPPER EXTREMITIES. Pains in the sub-axillary glands (11).
"Swelling of the axillary glands (11). Arthritic stiffness of the elbow
joint(ll). Heaviness of the forearm (11). Swelling of the forearm
jEthusa Cyna/pium. 165
(11). Lancinating drawing in the middle of the forearm to the carpal
joint (7). A lancinating thrust in the inferior extremity of the left
ulna (7). 255. Cramp in the hand (11). Twitchings in the left
thumb (7). Formication in the fingers (11). Contraction of the fin-
gers (11). Swelling of the fingers (11).
INFERIOR EXTREMITIES. 260. Boring pain in the inferior ex-
tremities (11 ). Lancinating tearing pain in the inferior extremities (11).
Lancinating and paralytic pain in the inferior extremities (11). Formi-
cation, which seems to be in the bones of the lower extremities (11).
Lancinations in the upper part of the thigh (7). 265. Lancinations
in the right knee, when standing up (7). Tearing pain deep in the
tarsi (7). Lancination in the right heel (7).
SKIN. Burning heat in the skin (11). °Eruptions, itching from
heat (11). 270. Dryness of the skin (11). °Dryness of the skin.
(11). °Eruption around the joints (11). °Nodosities of the skin (11).
Itching from heat (11). 275. Crawling itching (11). Itching in
the parts of the skin most slightly affected; they become swollen (11).
A herpetic eruption became very itching from heat, especially in the
evening' (11). °Tetters bleeding easily (11). The whole body is
blackish blue (2). 2<.'0- ° Anasarca (11).
SLEEP. Sleep without yawnings in the afternoon (7). Sleep dis-
turbed by frequent wakings (11). Sleep hindered by pains in the
limbs (11). Sleeps exceedingly well, the first night (7). 285. Roll-
ing of the eyes during sleep (11). Slight convulsive movements
during sleep (11). Frequent waking produced by a sensation of cold
(11). Waking followed by several hours of sleeplessness (11). Un-
quiet dreams (11). 290. Wearisome dreams, in the morning (11).
FEVER. Cold. Chill in the room (11). Chill after having
walked in the open air (11). Chill more frequent in the afternoon (11).
General coldness during sleep (11). 295. General coldness (11).
Internal coldness (11). Internal coldness sensible to the touch, so
violent that he cannot succeed in warming himself, accompanied by
somnolence during the whole day (6). Coldness embracing the whole
body and which is even perceptible to external touch, without thirst,
for two days (6). Redness of the face during the coldness (11). 300*
Horripilation in the open air (11). Horripilation with heat extending
over the whole body (11). Painful lassitude, hot breath and jactitation
during the horripilation (11). Heat. General heat (5). General
heat (11). 305. Heat notably increased (9). Complete absence of
thirst, notwithstanding the great general heat (5). Great suffering
during the heat (11). Sweat. General sweat (11). Sweat on going
to sleep (11). 310. He cannot bear to be uncovered during the
sweat (11). Pulse. Small, frequent irregular pulse (11). Rapid,
hard, small pulse (9). Irregular pulse (9). Full, accelerated pulse
(5)- 315. Imperceptible pulse (3). Small and frequent pulse (3).
The febrile symptoms manifest themselves, more especially in the morn-
ing, with very great malaise and disposition to delirium, which go off
during the sweat (11).
166 jEihusa Cynapium.
GENERAL. General malaise (5). Great agitation (3). 320*
Precordial anxiety (1). Anxiety and depression (9). Agitation and
very painful distress (4). Anxiety characterised by a sensation of
weight upon the chest (11). Cries of anguish (2). 325. Great
general weakness (5). °General weakness of children (13). Re-
markable emaciation of children (13). Want of power to hold up the
head and stand up (5). Epileptiform convulsions ; thumbs bent in-
wards, face red, eyes turned downwards, pupils dilated and immova-
ble, milky froth before the mouth, teeth set, pulse compressed, small,
hard and frequent, temperature of the skin natural (8). 330* Very
violent convulsions followed by death (9). ° Great liability to excoriate
the thighs in walking (15). °Great disposition to perspiration on the
slightest physical effort (13).
POST-MORTEM APPEARANCES. 1. A blackish serum was
found in the stomach ; the liver was hard and yellow, the spleen livid,
the mouth black ; but the abdomen was not inflamed (3).
2. Case of two children. One of the bodies exhaled a very strong
smell ; the other very little. The scalp adhered veiy closely to the
skull, face a little puffed, eyes half closed, pupils a little dilated, jaws
set. The tongue was not swollen, but covered with a whitish coat.
Upper extremities moveable ; inferior stiff; back, chest and extremities
covered with a great number of large blotches. The abdomen of one
was very much swollen ; it was less so in the other, but was green.
The vessel of the dura mater contained but little blood ; those of the
pia mater were engorged. All the sinuses were distended with a
black fluid blood. The brain was soft, with red points ; lungs normal ;
right ventricle of the heart filled with -black fluid blood. Stomach
reddish ; upper orifice contracted ; that of one of the children still con-
tained milk and fibres of the root, that of the other, only a yellowish
mucus. The one only displayed a few red spots ; the other very many.
There was no proper inflammation in the mouth, palate, oesophagus or
stomach. The small intestines were all a little red and filled with gas,
the large contained only a little excrement, and were no more inflam-
ed. The liver and spleen were gorged with blood. The duodenum
exhibited several spots of a clear yellow, as did the anterior biliary
edge, a part of the colon and of the epiploon. The gall bladder was
filled with clear, greenish brown bile. The kidneys full of blood, the
rapid cooling of the bodies, the slightly advanced stage of putrefaction
and the setting of the jaws, which according to some authors are
characteristic of paralysis, did not accord with the other results of the
autopsy. The author regards the bright yellow color of the parts ad-
jacent to the gall bladder as characteristic of poisoning by wthusa-cyna-
%>ium ; he considers that it is not identical with the common discolora-
tion of that region, inasmuch as the bile contained in its natural reservoir
was of a brownish green (9).
3. Extensive ecchymoses over the whole surface of the body ; in-
flammation of the stomach and peritonaeum ; engorgement of the
spleen, plethoric state of the lungs and heart. The brain not examined
(10).
AlcoliolrSulpTiuris. 167
4. The individual had previously suffered from a chronic gastritis.
Extreme emaciation, inflammation of the peritonaeum and bowels. Sup-
puration of the exterior membrane of the stomach ; sloughing spots at
various points on the small intestines ; scirrhous places in the epi-
ploon (10).
3. ALCOHOL-SULPHURIS.
ALO-SULPH. Liquor Lampadii ; carburet of sulphur ; bisulphuret
of carbon.
1. History, Description and Preparation.
Lampadius, in 1796, while distilling a mixture of pyrites and char-
coal, procured a clear liquid in the receiver, which he named Alcohol-
sulphuris, the alcohol of sulphur. It was at first regarded as a compound
of carbon, hydrogen and sulphur, until a more accurate analysis by
modem chemists showed that its component parts were one equivalent
of carbon and two of sulphur, CS 2 . (Ann. de Chim., vols. 42 & 84.
Phil. Trans., 1813.)
It is a transparent, colorless, volatile, and inflammable liquid, having
a specific gravity (1.272) greater than that of water, but less than
that of chloroform, and boiling at 160° Fahr. It has a very pungent
taste and a peculiar odor, somewhat ethereal, and yet partaking of that
of sulphuretted hydrogen. It is insoluble in water, and being exceed-
ingly volatile, is preserved under the surface of that liquid ; it is soluble
in alcohol and. ether, and in the oils generally. Its solvent powers are
somewhat remarkable, as it dissolves rapidly and in considerable quan-
tity, those two rather refractory bodies, sulphur and phosphorus. It
produces a great degree of cold by its evaporation, a thermometer
having the bulb kept moist by it and placed in an exhausted receiver
marking as low as — 80° Fahr.
It is prepared by placing small fragments of charcoal in a porcelain
tube, bringing it to high red heat, and then slowly passing the vapor of
sulphur through the incandescent mass, and conducting the product by
means of a glass tube to the bottom of a vessel containing ice-cold
water. The liquid is sometimes yellow from excess of sulphur, from
which it is to be freed by careful re-distillation at a low temperature.
It may be also prepared in Lampadius's method by distilling six parts of
168 Alcohol- Sulphur is.
yellow iron pyrites with one of charcoal. The vapor, instead of being
conducted into water, may be passed through a Liebig's condenser into
a receiver, kept at a temperature below freezing by a mixture of ice
and salt. (Gomelin, Handbuch ; Mitscherlich, Lehrbuch )
Its equivalent, according to the hydrogen scale, may be taken as
6 + 32 = 38.
2. Prior knowledge of its effects.
Very little can be gathered from medical writers concerning the use
of this remedy. Dr. Roth has collected the following observations.
1. Lampadius, its discoverer, published several clinical experiments
undertaken by Dr. Kappe in 1804 (Ueber den Schwefel-alcohol.
Freyberg, 1832, 2d ed., p. 54), but they are valueless to us, being badly
reported, and the drug having always been administered in combination
with camphor, volatile liniment or cologne water.
2. Dr. Wittich (De alcohole sulphuris, Gaettengse) recommends
it against chronic rheumatism, but mixes it with an ammoniacal
liniment.
3. Dr. Spielman's memoir (De alcoholis sulphuris virtutibus
chimicis et salutaribus, Marburgi, 1828) has not been examined.
4. Dr. Krimer, of Aix-la-Chapelle (Huf eland's Journal 79, p. 32),
has used it in asphyxia produced by the vapor of charcoal, in doses of
twenty drops every ten minutes. His cure of a white swelling by the
internal use of the bisulphuretis not so satisfactory, inasmuch as conium
was administered at the same time, and baths of wood-ashes employed
twice a week. He thinks highly of the remedy dropped slowly on to an
incarcerated hernia — it was very speedily rendered capable of reduction.
5. Dr. Mansfeld (Dresdener Zeitschrift 5, p. 454) recommends it
as an emmenagogue, and is followed by others in so doing, but on exam-
ining his experiments we find that he used it containing iodine in
solution.
6. Dr. Ott (Casper's Wochenschrift, 1838, No. 13) is also a great
admirer of this remedy as efficient against rheumatism ; but on reading
his cases, the cessation of an articular rheumatism after every sort of
treatment for six months, ending with the employment of the bisulphuret
of carbon in conjunction with Russian vapor-baths, gives us no great
reason to expect very great wonders of the remedy.
1. In addition to the authorities collected by Dr. Roth we may add
the following :
" It may not be out of place here to state that I have employed, with
great success, the bisulphuret of carbon to enlarged, indurated, lymphatic
glands. In the first instance I rubbed equal quantities of the bisulphuret
and alcohol upon the parts affected, but without any effect upon the
glands. But as its effects were so great when its vapor was confined to
the eye, I was led to employ it in the form of vapor and by means of
glass bottles. By these means I excluded the action of the medicine
from the external air, and thereby prevented its speedy evaporation.
Alcohol-Sulphuris. 169
When it had been applied about one minute the patient felt the part
very cold, but immediately after, a gradual heat, accompanied with great
prickling — the heat increasing the longer the medicine was kept in
contact with the part, until it could no longer be endured, On removing
the glass, the part was red to an extent two or three times greater than
the part enclosed. In a few days the change in the size of the glands
was very great, and by its daily repetition a complete and speedy
removal of the disease was effected. I also find that its action upon
diseased glands is more decided if the surface of the skin is well moist-
ened with water previous to the application of the bottle to the part."
— (Mr. Turnbull, in Pharm. Journal, vol. 2, p. 352.)
3. Digest of the Symptoms.
The following symptomatology is translated from Dr. Roth's Materia
Medica, vol. 1, p. 441. He cites the following
AUTHORITIES. I, Knaf, Dissert, inaug. med. de liquidi Lam,'
padii virtute medica. Pragae, 1835. 2. Buchner, Augsburg Journal,
1850, p. 65. 3. Mad. H, ibid. 67. 4. Held, ibid. 69. 5. Anna
Gasberger, ibid. 71. 6* Koningshofer, ibid. 73. 7. Mad.
Koningshofer, ibid. 75. 8t M. M., ibid. 77. 9. Primbs, ibid. 78.
10. Pemerl, ibid. 81. 11. Moser, ibid. 90. 12. Quaglio, ibid.
92. 13. Vehsemayer, Leipsig Journal 6, p. 269.
The pathogenetic symptoms are in roman letters, the toxicological in italics, the
curative are distinguished by a cypher before them.
MIND. Mental. 1. Excitement of the intellectual faculties (1).
Vivacity of intellect (1). Head confused, difficulty in thinking with
acceleration of the pulse (3). Distraction and difficulty of understanding
what one is reading (10). 5- Unfitness for every kind of exertion;
somnolence when at work and pressure on the eyes (11). Moral*
Bad humor, irritability (3). Sad frame of mind, obstinacy (4).
Moroseness and disposition to violent anger (4) . Transport of passion,
rage (10).
HEAD. Headache in general. 10. Slight headache, lasting
only two hours (4). Headache when reading (7). Pressive headache
(7, 9). Heat in the head and face (9). ° Tearings in the head (5). 15.
Embarrassment of the head (11) — with distraction (10) — as though
from spirituous liquors (4). Head confused (1, 6, 7, 9). Confusion of
the head (5). 20. Heaviness of the head (1). Vertigo (2). Sudden
vertigo (4). Frequent attacks of vertigo when sitting (4). The head-
ache is increased after drinking wine (2). 25. The morning headache,
which had disappeared in the afternoon, returns in the evening (9).
Frontal region. Slight frontal headache (9). Slight, transitory,
frontal pain which gradually approaches the temporal regions (9).
Slight pain in the forehead, drawing towards the left parietal and
remaining there two hours (9). Sensation of heat and moderate pres-
170 AlcoholrSulphuris.
sure in the forehead, and necessity to wipe it continually with the hand
(9). 30. Embarrassment of the head, lancinations and twitching pain
in the forehead (11). Tearing pain in the frontal region lasting several
hours and disappearing in the direction of the temples (4). Embarrass-
ment and vertigo in the sinciput (2). Embarrassment and pressure
in the sinciput (7). Frontal region confused (3). 35. Heat of
the forehead (5). Sensation of pressure in the sinciput (1). Slight
pressive frontal headache (9). Embarrassment of the head, slight
aching and digging in the forehead (11). Pressure and dull but tran-
sitory pain in the forehead all day (11). 40. Pressive pain in the
frontal region stretching towards the temples and some tearings in the
same direction (9). Pressive pain in the frontal region, with feeling of
heat, lasting two hours (9). Malaise and pressive frontal headache (6).
On waking in the morning, slight pressive frontal headache, which soon
vanishes (9). Pressive frontal headache, with few interruptions during
the whole day, accompanied by transitory attacks of pain in the tem-
ples (6). 45. Dull pressive pain in the forehead, all day (6). Dull
pressure in the forehead and temples, with desire to sleep (6). Pressive
frontal headache, increased by stooping and reading (7). Drawing and
tearing pain stretching from the forehead to the temples, lasting all
day, more severe in the room and during rest ; ameliorated by walking
in the open air (3). Dull pain in the frontal region, with pressure on
the eyes (7). 50- Dull pain in the frontal region, with nausea and
heaviness in the whole head (3). Vertigo in the sinciput, which almost
makes him fall forwards (2). Parietal region. Pressure in the right
parietal bone (9). Pressure at the origin of the temporal muscle (4).
Temporal region. Thumping pain on the two temples, lasting a long
while, caused and aggravated by moving the head and by stamping on
the ground (0). 55. Tearing pains in paroxysms in the left temporal
region (7). When stooping, transitory tearing in the right temporal
region (7). Lancinations in the left temporal region, which stretch into
the occiput (9). Pressive pain in the temples (9). Violently pressive
pain in the right temple with malaise, desire to vomit, borborygmi,
without colic (6). 60. Pressure on the two temples from without
inwards, subsequently extending also to the vertex (2). Dull pain in
the temporal and frontal regions (6). Drawing pain in the left temple
(6). Drawing pain in the temples (6). Scalp. Itching of the scalp
(3). 65. Little pimples on the scalp, which cause a smarting pain (10).
EYES. Sensation of pressure in the orbits (1). Burning in the
edges of the eyelids (7)— which are red (7). Itching of the right lower
lid (7). 70. Itching of the lids, as well as of the skin of the back and
two thighs, lasting two days (4). A little pustule, which itches a good
deal, forms on the upper lid, accompanied by a sensation of acute
burning (4). Pustule lasts four days (4). Heaviness of the lids (7).
Pressure on the eyes ; he is obliged to close the lids (11). 75, Pressure
on the eyes (9, 11). Pressure and itching in the eyes (4). Pressure
on the globe of the left eye and feeling of heat "in the interior (9).
Dull lancinations in the right eye when reading (10). Single lanci-
Alcohol-Sulphtiris. 171
nations in the right eye (10). 80. Transitory dilatation of the pupils
(3). Transitory dilatation of the pupils and accelerated pulse (3).
Dilated pupils (5). Disturbed and veiled sight (3, 10). Eyes fixed
(5). 85. Abundant secretion of whitish, yellowish mucus in the eyes
(4). Lachrymation of the eyes when reading (9). Paroxysms of
lancinating and twitching pain alternately in the different muscles of the
eye (10). Smarting in the orbicular muscle of the right eye towards
its internal angle, especially during movement of the lids (10). Twitch-
ing lancinations in the superior rectus (10). 90. Trembling of the
eyelids (6).
EARS. Sharp, isolated stitches in the ear (10). Lancinations in
the right ear (9). Lancinations in the left ear (V). Sharp lancinations
in the right ear (10). 95. Single stitches in the right ear after the
noon meal, renewed every quarter of an hour (9). The lancinations in
the ear increase towards evening ; they last a quarter of an hour (9).
Paroxysms of pressive pain in the right ear, as though some one were
striking upon the tympanum with a dull instrument (9). Boring in
the right ear (10). Tinkling before the ears, lasting four days (4).
NOSE. 100. Obstruction of the nose (3, 4). The nose is some-
what stopped on blowing it (10). Creeping in the end of the nose
like a desire to sneeze (10). Sneezing (10). Sneezing with traces of
blood in the nasal mucus (10).
FACE. Face red and puffed (5). 105. Heat of the face and
hands, especially of the palms (1). Heat of the face, especially of the
cheeks, in the afternoon (1). Heat of the cheek for three quarters of
an hour, confusion in the sinciput and sensation of compression of the
cerebral hemispheres (2). °Lancinations and tearings in the right
cheek, stretching into the temporal region ; they had lasted two months
(5). Disagreeble sensation in both cheeks during the abdominal
pains (10).
MOUTH. Lips. 110. Lips dry (4). Burning of the lips and
tongue (12). Twitching of the corners of the mouth (5). Jaws.
Drawing pain in the right inferior maxillary (9). Cavity Of the
UlOllth. Burning in the cavity, breath hot, oppression of respiration
and pressure on the sternum (2). 115, Irritation of the cavity and of
the isthmus of the pharynx, followed by a sensation of contraction of
the larynx, cough, even to vomiting, and accelerated respiration (2).
Teeth. Odontalgia in the evening and night ; the pains are burning,
and aggravated by the heat of the bed (5). Teeth on edge (1).
Throbbing and burning pain in the last molar on the left side, not very
violent, but lasting all night (4). The toothache in the posterior molar
increases ; a swelling of the gum forms around the tooth which extends
towards the palate, occasions tension and itching, but no pain, and ren-
ders mastication difficult (4). 120. The swelling of the gums does
not disappear until the fourth day (4). The toothache comes on in the
afternoon, is tearing and drawing ; aggravated in the evening ; dimin-
ishing towards midnight ; the cold open air makes it more endurable.
Slight shooting in a carious upper tooth (10). Shootings from the
172 Alcohol-Sulphuris.
crown to the root of a perfectly sound right inferior molar (10). Shoot-
ing pain in paroxysms in the carious tooth (10). 125. Dull drawing
and shooting toothache in an upper carious molar and in the corres-
ponding lower tooth, in the morning on waking ; it persists in the
upper tooth until after he has got up (10). Taste. Pasty, disagree-
able taste in the mouth (10). Pasty taste, want of appetite and fre-
quent yawnings (11). Foul taste of the pharyngeal mucus which he
raises (10). Metallic taste (9). 130. Metallic^ sulphurous taste (1).
Bitter, sharp taste in the morning (4). Very repulsive, acrid taste (4).
Sweetish, putrid taste (3). Blunted taste during the whole day (2).
Tongue. 135. Burning on the point of the tongue and in the
pharynx (9) Transitory burning, as if from pepper on the point of
the tongue and iu the pharynx (6). Burning on the tongue and in
the pharynx (12). Shooting burning on the tongue (2). Sensation of
pricking on the tip ot the tongue (9). 140. Sensation of cold on the
tongue, followed by a lancinating burning, and this succeeded by a feel-
ing as though he had taken pepper (at once) (1). Saliva. Accumu-
lation of saliva in the mouth with sweetish taste, during the whole day
(6). Malaise and accumulation of saliva in the muuth (6, 10). Ac-
cumulate of saliva in the mouth (10). Increased salivary secretion
(9). 145. Increased salivary secretion (5). Very frequent spitting
(1). Saliva viscid with desire for drink (2). Palate. Burning in
the velum palati (2). "Swelling of the uvula and velum, which are
pale red (5).
APPETITE. 150. Increased appetite (1). Appetite somewhat
increased (4). Appeti.e and salivary secretion increased (1). Hunger,
accompanied by rumbling in the belly (2). The appetite continues,
notwithstanding the great constrictive pain in the stomach (9). 155,
Hunger, and yet repugnance to food (10) Diminution of appetite
(10). Decrease of appetite at noon and m the evening (18) Com-
plete absence of appetite (1) Rapid satiety in eating (11). Thirst.
160. Very violent thirst; beer is plea^anter tlian anything (4).
PHARYNX. Burning in the throat, extending into the stomach
(3). Violent burning in the pharynx, with malaise (9). Burning pain
in the pharynx (9). Burning in the pharynx and oesophagus (4).
165. Burning and scraping in the pharynx and oesophagus (9).
Burning and scraping the whole extent of the pharynx (o). Very
violent burning in the pharynx and stomach (5). Feeling of acridity
in the pharynx (on swallowing the drug) (l). Scraping in the throat
(10). 170. Scraping in the throat for a whole day, as though a cold
were about to set in (7). Sensation as though there were a hair in
the throat (3). Difficult deglutition (d).
STOMACH. Eructations. Emp.y eructations (6). Unsatisfac-
tory eructation* (10). 175. Frequent eructations, with the smell and
taste of the daig (1, 6). Flatulent eructations smelling of black radish
(10). Eructations and inclination to vomit, especially when he
changes from the open air to a room or vice versa (11). Aciid and
burning eructations twice (10). Very abundant eructations (2). ISO.
Alcohol-Sulphuris. 173
Regurgitations! Escape of inodorous flatulence, with burning at the
scrobicuius (10). Sour, burning, acrid regurgitations (pyrosis) one or
two hours after eating (10). Regurgitations (2). Regurgitations of
air (7). Nauseating regurgitations (1). 185. Regurgitations and
discharge of wind downwards (12). Regurgitations and desire to
vomit (9). Regurgitations and malaise (9) Continual acid regurgi-
tations, but without vomiting (o). °Frequent sour regurgitations (5).
190. Regurgitations of something sour (3). Acid regurgitations (3).
Vomiting, Desire to vomit (3, 12). Desire to vomit wiih embar-
rassment of the head (2). Desire to vomit, and pressure in the stomach
but very transitory (6). 195. Vomiting of a small quantity of bitter
water (7). Epigastric RegiOU. Sensation of burning in the sto-
mach, aggravated by external pressure (9). Burning in the scrobicuius
and in the stomach (o). Burning in the stomach and hepatic region,
increased by external pressure (9). Heat in the epigastric region,
which ascends and occupies the whole chest (l). 200. Agreeable
heat in the whole stomach (1). Violent heat ascending from the sto-
mach to the head, and descending to the umbilical region (l). Pain in
the stomach, especially on taking a deep inspiration, after breakfast
(7). Lancinations in the stomach (5). Transitory lancination in the
epigastric region (6). 205. Feeling of malaise in the stomach (7).
Malaise and sensation of emptiness in the stomach (11). Malaise in
the stomach, nausea, regurgitations of air having the taste and smell of
the drug (11). Fulness in the stomach (9). Sensation of fulness of
the stomach, with eructations, yawnings and desire to vomit (2). 210.
Sensation of fulness in the whole epigastric region, accompanied by
slight vertigo (2). Sensation of fulness at the stomach, which is sensi-
tive to the touch (9). Supper dispels the fulness of the stomach and
the vertigo (2). Pasty taste, pressure at the stomach and lancinations
in different parts of the hvpogastrium (11). Slight pressure at the
stomach (1, 7). 215. Pressive pain in the stomach (9). Pressure
and sensation of cold at the stomach (3). Pressive pain in the epigas-
tric region and very abundant emission of flatus (6).
ABDOMEN. Abdomen inflated (2). Inflation of the abdomen,
after eating (11). 220. Inflation of the abdomen, with sensation of
excoriation (u). Borborygmi (6, 10). Great noise in the intestines,
(3). Borborygmi and tearing colic in the abdomen (5). Borborygmi
and sensation of dryness in the throat (7). 225. Borborygmi, escape
of flatus and desire to urinate (1). Indefinable colic pains after the
noon meal (3). Malaise in the abdomen, followed by a soft faeculent
stool (10). Malaise in the hypogastrium increa>ed by stooping and by
movement (10). Abdomen full and distended, soft stool (2). 230.
Frequent slight colics (1). Slight intestinal colic from time to time,
and desire to urinate (1). Slight colic (9). Slight colic pains after
eating (10). Slight colic pains followed by a liquid, unsatisfactory
evacuation (10). Colic and borborygmi, as if a diarrhoea were about to
come on («). Colic such as follow* the exhibition of a purgative (8).
Colic here and there with emission of flatus (10). Colic, emission of
flatus, stools and remission of the pain (7). Colic pains which disappear
174 Alcohol-Sulphuris.
on going to stool (6). 240. Colic and regurgitation of the milk taken,
without malaise and without vomiting (7). Violent colic in the even-
ing after having eaten a little salad, followed by a stool of globular
substances (10). Colic, with movements of wind in the abdomen on
waking at 4, a. m. ; on inspiration and by external pressure the pains
become lancinating and become permanently located for an hour nearly
in the region of the caecum (10). Malaise in the hypogastrium, abundant
expectoration and desire to vomit after having drunk coffee (10).
Itching on the abdomen and right shoulder after rising and washing
the body with cold water. (10) 245. Sensation of excoriation in the
abdominal integuments (9). Painful sensitiveness of the abdomen to
external pressure (7). Umbilical region. Colic in the umbilical
region with a stool (6). Cuttings in the umbilical region and slight
attack of malaise an hour after having dined (10). Attacks of pinching
twitching in a little spot two inches from the navel towards the right,
lasting a half minute (10). 250. Slight lancinating and pruritous pain
on the right side below the navel, followed by an almost liquid stool
(10). Single, very acute stitches on the right of the umbilical region,
extending towards the bladder (10). Colic in the small intestines, -with
emission of much flatulence (6). Hypochondria. Lancinating and
twitching pain, first in the right then in the left hypochondrium,
remaining in both sides for several minutes, and not increased either by
pressure or movement (10). Paroxysm of lancinating pain in the right
inferior costal region, two inches from the scrobiculus, at five o'clock,
p. m. (10). 255. Paroxysm of disagreeable but indefinable pain in the
region of the left lobe of the liver (10). Lancinating twitching in
the left hypochondrium (10). Two pappy stools at 11, a. m.; preceded
by pains in the region of the left lobe of the liver, and followed by
pains in the caecal region (10). Hypogastrium. Dull shootings when
bearing upon the hypogastrium (6). Cuttings in the hypogastrium,
followed by a moderately soft stool (10). 260. Slight cuttings in the
hypogastrium ; contact is disagreeable, and seems to excite them after
they have ceased; stooping causes feelings of malaise (10). Slight
colic pains in the hypogastrium as though diarrhoea were about
to set in (10). CSBCal region. Lancinating and twitching pain in
the region of the caecum (10). Lancinations, pinchings in the region
of the caecum (10). The lancinating pain in the region of the caecum
is not relieved by the discharge of flatus. Turning from one side to
another, or doubling up the body, aggravates the pain or excites it afresh
when almost relieved (10). 265. Dull shootings in the region of the
caecum, with discharge of flatulence in the morning on waking (10).
Lancinating, dull, itching pain in the region of the caecum, lasting one or
two minutes (10). — Isolated lancinations here and there in thefeft side
of the abdomen and * n the right eye when reading (10). Lancinating,
nipping pains in the right side, frequently during the day (10). — He
discharges, during the day, a great deal of flatulence, having the smell
of the drug (11). 270. Discharge of very fetid wind (12). Discharge
of flatus, with sensation of itching in the rectum (3).
STOOL, Desire to go to stool (9). Pressing desire for stool at
Alcohol-Sulphuris. 175
noon (2). Two stools in succession without any pain (V). 275. Hard,
insufficient stool, with slight tenesmus towards evening (10). Consti-
pation (10). Evacuation drier than common (10). Hard stool at first,
then soft, with rumbling in the abdomen as though a stool were about
to follow (10). Stool at first hard, then soft, with burning at the anus,
followed three hours afterwards by a second fseculent evacuation like-
wise accompanied by burning at the anus (10). 280. Difficult stool,
soft and scanty, as though from inactivity of the rectum (10). Pappy
stool preceded by cuttings, shortly after breakfast (10). Two liquid
stools (9). Liquid stool having the odor of the drug (11). Stool
liquid, as if after a purge (10). 285. Slimy diarrhoea (9). Watery
diarrhoea (9). Liquid diarrhoea and violent pain above the sternum,
twice repeated (9). Sudden diarrhoea, after having dined with great
satisfaction, recurring twice in the afternoon accompanied by colic (9).
Violent diarrhcea ; evacuations of a sour smell and accompanied by
tenesmus (o). 290. °Chronic diarrhcea, appearing every month or six
weeks, lasting one or two days with colic, especially in the umbilical
region, which is drawn in, with liquid, yellowish, frothy evacuations
of a sour smell and accompanied by tenesmus (3).
ANUS AND RECTUM. Transitory lancinations in the rectum (6).
Itching and burning at the anus (9).
URINE. Desire to urinate (l). Increased but not altered secretion
of urine (1).
GENITAL ORGANS. 295. Flaccidity of the genital parts, a
constant symptom during the whole proving (2). Transitory irritation
in the navicular fossa at night, without desire or need to urinate (4).
Erections (9). Very restless night; erections and pollutions (9).
Lancinating and twitching pain in the left testicle lasting two minutes
(10). 300. Menses five days before the time without any pain (3).
LARYNX. Heat and irritation of the larynx, temperature of the
expired air, higher (2). Hoarseness, irritation of the larynx, especially
of its posterior surface, manifesting itself by a continual desire to hawk,
but rarely by a cough, for thirty-six hours (2). Hoarseness for two
hours (9). Voice a little veiled without any other catarrhal symptom
(10). 305. Veiled voice (10). Rough veiled voice (10). Sensation
of scraping and transitory lancinations in the neck (6). Sensation of
scraping in the larynx provoking cough (6). Irritation in the neck
provoking a cough (12). 310. Desire to cough provoked by a tickling
at the bifurcation of the bronchi (2). Slight, dry cough (6).
CHEST. Sensation of heat in the chest (5). Congestion in the
superior portion of the lungs manifested by accelerated respiration (2).
Oppression of the chest aggravated by going up stairs (2). 315- The
oppression of the chest is aggravated in a room the air of which is not
renewed, and is accompanied by anxiety (2). Fulness of the chest and
embarrassment of respiration, arising in the anterior portion of the
diaphragm (2). Sensitiveness of the anterior portion of the thorax
when sneezing (2). Dull, pressive pain in the right side of the chest
(6). Pain in the left half of the chest and beneath the sternum from
N
176 Alcohol-Sulphuris.
time to time (9). 320. Attack of stitches in the left half of the chest
without cough (9). Transitory and isolated stitches in the chest and
helow the left false ribs (10). Dull stitches in the inferior part of the
right chest (10). Pressure beneath the sternum (9). Transitory-
stitches near the sternum on the left side after having drunk coffee (10).
325. Itching stitches in the nipples (male) (10).
BACK. Cervical. °Stiffness in the muscles of the right side of the
neck (5). Drawing pain in the right sterno-mastoid muscle (6).
Itching stitches in the right sterno-mastoid (10). Painful scraping as
though from a foreign body in the left side of the neck at 9 a. m.,
extending into the left ear when swallowing, lasting one or two minutes
(10). LoiUS. 330. Lancinating and twitching pain in the right lum-
bar region lasting a minute or two (10). Sacrum. Tension in the
sacrum with some shocks towards the coxo-femoral articulation (2).
Tearing and pressure in the sacrum (9). Drawings in the sacrum in
the afternoon (9). Shoulders. Lancinating and twitching pain in the
right scapulo-humeral articulation (10). 335. Very slight lancinating
pains extending from the shoulder-joint to the carpus, in the morning
(3). Jerking lancinations in the arm and shoulder joint (10). Attacks
of lancinating and itching pain in the left deltoid (10).
SUPERIOR EXTREMITIES. Slight formication along the whole
right arm with feeling as though the arm were about to become numb
(3). Numbness of the left arm with pain and feeling of fatigue (9).
340. Pressive pain in the right arm from time to time (9). Itching
on the anterior surface of the right arm and fore-arm, in the bend of the
left elbow and on the thighs (10). Paroxysm of lancinating and dull
pains on the internal side of the arm and thigh (spasmodic contraction
of small isolated muscular fasciculi) (10). ElbOW. Transitory tearing-
pains in the right elbow and left shoulder (8). Twitching in the region
of the olecranon (10). Fore-arm. 345. Attack of lancinating pain
at the insertion of the biceps on the fore-arm during the whole evening
and succeeding night (10). Slight lancination extending from the left
olecranon along the extensor muscles into the carpus, several times
during the day (3). Formication extending from the olecranon to the
end of the fingers, excepting the thumb (3). Formication in the fore-
arms, alternating with slight shootings (3). Pressive pain in the left
fore-arm aggravated by touching and by resting n the fore-arm (9).
350. Trembling of the left fore-arm, with lancinations especially about
the right joint (9). A spot on the right fore-arm (urticaria) which
itches a good deal and forces him to scratch (10). Several isolated
papules on the right fore-arm which itch when touched (10). Itching
in a small spot on the right fore-arm, inclining one to scratch, and
followed by an eruption of small pimples (10). " Carpus. Pain in the
carpal joints (9). 355. Lancinations in the left carpal region (9).
Metacarpus. Slight, twitching pain in the joints yf the hand for several
weeks, sometimes in the right, at others in the left, several times a day,
but only lasting a few seconds (11). Lancinations by jerks in the
metacarpophalangeal articulation of the index and in the fleshy part
Alcohol-Sulphuris. 177
of the right great toe (10). Dull shooting in the metacarpopha-
langeal articulation of the left index (10). Fingers. Lancinating and
twitching pain in the first phalanx of the fourth finger of the left hand,
frequently renewed (10). 360. Lancinations in several of the finger-
joints (10).
INFERIOR EXTREMITIES. Hips. Violent itching, forcing him
to scratch in the region of the right hip (10). Drawing from the left
hip-joint to the knee-joint, with feeling of a sprain in the knee (4).
NatCS. Violent pain in the ischiatic tuberosity and along the posterior
surface of the lower extremity, in the afternoon, while riding in a car-
riage (10). The lancinating and itching pains often appear in different
parts of the body, especially in the region of the right ischiatic tubero-
sity and at the insertion of the gracilis and sartorius (10). Thighs.
365. Shootings in the middle of the right thigh (10). Occasional
shootings in the muscles of the thighs and in the toes (10). Shooting
pain in paroxysms along the middle of the thigh like a neuralgia, after
the noon meal ; it lasts half an hour, is very painful and is repeated the
next day before noon. In the afternoon the same pain is perceived
between the tibia and the fibula (2). Itching on the two thighs, on
the right side of the back as far as the renal region, and right fore-arm,
forcing him to scratch in the morning on waking (10). Little colorless
pimples on the thighs, on the right side of the back and arm, the
itching of which is aggravated by scratching ; they become red and
form an eruption analogous to scabies (10). 370. Drawing pain in the
left thigh when walking (7). Knees. Pain and drawing in the knee-
joints (12). Tearing pain in the knee-joints and tarsal-joints, in the after-
noon (9). Lancinating pains in the internal side of the left knee extending
into the great toe (4). Tensive pain in the right ham when walking and
extending the foot (6). 375. Lancinating and twitching pains, some-
times in the hollow of the right ham, sometimes in the hypogastrium,
spermatic cord, lasting until after dinner (10). Legs. Itching in the
calves and legs (10). Itching of the legs, in the evening when going
to bed (10). Feet. Frequent transitory pains, in paroxysms, in the
joints of the feet (11). Pain resembling the result of fatigue after a
prolonged walk in the joints of the feet (11). 380. Tearing pains in
the left foot, especially in the tarsal bones, transitory (6). Twitching
lancinations at the insertion of the tendo-Achillis into the calcaneum
(10). Pain in the point of insertion of the tendo-Achillis into the
calcaneum when going up stairs (10). Dull aching in the left heel (6).
Transitory twitching pains in the dorsum of the right foot and in the
right carpal region, equally transitory (G). 385. Violent cramp in the
sole of the right foot, removed by pressing the foot firmly upon the
ground (10). Several lancinations in the fleshy part of the great toe
(10).
SLEEP. Somnolence (4). Great somnolence during the whole
day (11). Somnolence during the whole day and agitated sleep at
night; head heavy; he is obliged to change his position every instant
(11). 390. Somnolence at 2 p. m. (3). Somnolence at 3 p. m,, and
178 Alcohol-Sulphuris.
at night she cannot sleep (3). Somnolence after noon and in the
evening she goes to sleep with equal ease (3). Very great somnolence
in the evening, in company (6). Great somnolence and wavering in
the head, in the evening (11). 395. Very great somnolence with
heaviness of the upper eyelids which close involuntarily (7). Sleep-
lessness on account of dryness of the skin and a general unpleasant
heat ; he is obliged to rise and moisten his skin with cold water in
order to produce a perspiration, but without result (11). The pains
in the head prevent him from sleeping (5). She goes to sleep very late
(3). Late and very restless sleep (4). 400. Deep and refreshing
morning sleep (3). Restless sleep and heavy head for several nights
in succession (11). Very restless night, alternate unquiet dreams and
wakings (9). Very restless nights with erections and burning in the
urethra (9). Sleep interrupted after midnight, full of disagreeable
dreams (2). 405. Sleep troubled by many disagreeable disquieting
dreams accompanied by tears (7). Restless sleep disturbed by dreams
(4). . Restless sleep, disturbed by confused dreams (3). Sleep dis-
turbed by dreams (7). Much dreaming towards morning (10).
SKIN. 410. Skin hot and in many places burning as though he
had touched nettles (ll). Sharp, itching stinging in different parts of
the skin (10). Itching lancinations in different parts of the integuments
(10). Itching in various parts of the skin, in the morning in bed, not
very violent if it is not aggravated by scratching (10). Bleeding and
burning of the scabious eruption from scratching (10). °Impetigo on
the backs of the hands, three cases, little vesicles on a red, inflamed,
swollen base, sometimes nearer, at others more separated, containing a
yellowish cloudy serum which discharges and forms thick yellowish
crusts, which sometimes irritate the neighboring parts and torment the
patient with the violent itching to which they give rise. Three globules
(dilution ?) were administered ; shortly afterwards the hand swelled
considerably with violent smarting. At the end of eight or twelve
hours the pain and swelling began to diminish and the impetigo dis-
appeared in from three to eight clays (13).
FEVER. Cold. General coldness (3). Sensation of cold and desire
to go to stool (9). Sensation of general internal heat and coldness of
the feet (7). Heat. General heat, slight headache, strong pulse, cramps
in the calves and toes, without thirst. The heat lasts two hours and
leaves great weariness behind (8). 420. Coldness of the feet and
general heat of the upper part of the body (2). Perspiration.
Cutaneous perspiration suppressed (11). Skin dry, perspiration sup-
pressed, appetite diminished for several weeks (11). Pulse. Arterial
pulse more, frequent (l). Pulse accelerated for ten minutes only; it
rises from seventy-six to ninety-two (3). 425. Acceleration of the
pulse (4). ' Pulse ninety to ninety-Jive (5).
GENERAL. Great weariness and depression (11). Extraordinary
fatigue after a long walk ; respiration a little embarrassed (6). General
weakness, especially in the left arm, in the morning, disappearing towards
noon (9). 430. Transitory physical excitement (4). She lies down,
Amphisbcena-vermicularis. 179
weeps and groans (5). Transitory attacks of malaise (10). Transitory
attacks of malaise as though he were going to faint (11). Uncom-
fortable all the afternoon (10). 435. The malaise returns in fits, even
after having been to stool (10). The attacks of malaise are especially
brought on by the compression of the abdomen in the sitting position ;
the open air seems to mitigate them (10). Lancinations in paroxysms
in different parts of the body (10). Twitching lancinations in different
parts of the body, especially in the muscles of the right eye (10).
Twitching (jerking) pains, sometimes in the forehead, at others in the
joints of the feet, and again in the joints of the arm (11). 440. °Great
liability to rheumatic pains (5). ° Rheumatic pains in different parts
of the body. The symptoms are diminished after eating and by motion
in the open air (10). The drug does not seem to act for more than
twelve or eighteen hours (6).
4. AMPIIIRB^ENA-VEKMICULAKIS.
AMPH. Amphisbaena.
1. Description and Preparation.
This genus of serpents belongs to Brazil and other parts of South
America, and derives its name from the fact that its head is so small
and its tail so thick and short, that they are with difficulty distinguished
from each other, while, at the same time, it has the habit of proceeding
either backwards or forwards as occasion may require. It is said to be
destitute of fangs and to be perfectly harmless and inoffensive, living for
the most part upon ants and other insects. Mure, from whose Patho-
genesie Bresilienne the following proving is taken, gives the following
description of the species used. " Its body is cylindrical, from fifty to
eighty centimetres long, terminated by a very obtuse tail. It is destitute
of proper scales, but its skin is divided into quadrilateral compartments
disposed in rings around the body, two hundred and twenty-eight on
the body and twenty-six on the tail. The lip of the cloaca is divided
into six long and narrow plates ; the head is small,! a little pointed,
protected by scutella and confounded with the neck. The eyes are very
small ; the jaws not dilatable, the teeth conical, bent, unequal and
distinct from each other ; the nostrils lateral and pierced in a single
naso-rostral plate. Its color is brownish above and a slightly pinkish
white beneath.
180 Amphisocena-vermicularis.
" We procured the poison by cutting off a portion of the jaw from
the living animal and immediately triturating it." If the Amphisbaena
is destitute of fangs and harmless, according to the opinion of the natu-
ralists, this poison will be somewhat apocryphal.
2. Prior use.
The dried and powdered flesh of the Amphisbaena is said to be
administered by the natives of Brazil as a specific in dislocations, sprains,
and bruises.
3. Digest of the Symptoms.
AUTHORITIES. Mure, Pathogenesie Bresilienne, p. 261.
GENERAL. Debility. Sadness and great lassitude in the morning,
removed when walking. Tender sadness tending to mildness. Great
pain in the whole vertebral column, aggravated by walking, moving the
arms and stooping. 5. Depression. Ennui. Impatience.
HEAD. Heaviness in the forehead and parietal regions. Heavi-
ness in the forehead. 10. Great confusion and vertigo with swinging
sensation, which seems to tend to one side by a series of successive
impulses, and then to the other by a similar operation. Repeated
strokes in the right side of the forehead as though he were struck by
hail. Sweat on the head. Disturbance of the sensations ; he expe-
riences dreadful headaches and would believe his feet were in his brain.
Confusion as if from intoxication, when turning the head.
EYES. 15. Pain as from a stye in the internal canthus of the right
eye. Continual trembling of the right upper lid, and especially of the
left. Constriction of the right eye ; it feels as if it were tied. Pain
and lancinations in the external canthus of the left eye. Feeling of a
grain of sand in the right eye. 20. Fatigue of the eyes in the even-
ing ; pain and pricking when looking at the light. Lachrymation and
constriction of the left eye.
EARS. Pain in the meatus as if from the introduction of air.
FACE. Little prickings and heat over the cheekbone of the right
side. Dull pains on the right side of the inferior maxillary bone. 25.
Pains and lancinations attacking the whole right side of the head.
Pains in the right lower jaw and some swelling, aggravated by the air
and moisture. Swelling of the right lower jaw, aggravated by the
air. Very large and painful pimple on the left side of the upper lip,
ending in suppuration.
MOUTH AND THROAT. The teeth feel prolonged and are set
on edge, especially the right inferior molars, and in the interior of the
mouth. 30. The toothache k worse in the afternoon and evening.
He cannot chew without pain, but the impression of liquids is not
painful. Swelling of the tonsils. Difficult deglutition ; he cannot swal-
low his saliva.
ABDOMEN. Protrusion of an umbilical hernia. 35, Coldness
Anagallis-arvensis. 181
and pains in the epigastrium. Tearing pain in the navel all day Sup-
puration of an inguinal hernia. The hernia is painful, and pent-up air
is perceived in it. Lancination like a dagger-stroke in the navel.
STOOL. 40. Constipation.
EXTREMITIES. Very painful swelling of the arm, (15th day).
Cramp in the left leg. Painless retraction of the legs. . Cramps in the
left leg ; it drags in walking as though paralysed.
SLEEP. 45« He wakes precisely at midnight for ten days in suc-
cession. Interrupted sleep.
SKIN. Red miliary eruption (dry itch cured) in extensive plates
of an elliptic form ; furfuraceous desquamation takes place in every
spot when the eruption is healed. The spots of miliary eruption of
little red pimples extend over the whole chest, neck and back, with
itching, more violent in the morning and diminishing until evening.
A white vesicle forms by degrees on every papule and discharges a
clear lymph, after which the eruption dries up on the fifth day. 50i
Miliary eruption of little pimples, especially on the forearm.
5.— ANAGALLIS-ARVENSIS.
ANAG-. Scarlet Pimpernel. Red Chickweed. Poor Man's
Weather-glass. Fr. Anagallis male. Mouron rouge.
1. Description and Preparation.
This plant belongs to the order of Primulacece in the natural sys-
tem ; Pentandria, monogynia, Linn. Calyx and corolla, five-parted ;
stamens, five ; capsule globose, opening horizontally all round. A
square, procumbent stem, with opposite branches, and ovate, sessile,
opposite leaves, dotted underneath, about half an inch long. The
flowers are borne on solitary axillary peduncles longer than the
leaves ; the corolla scarlet, with a purple centre. It is found near New
York, and on Long Island, and Staten Island, and is said to be the
European species introduced. It flowers from June to October.
The expressed juice of the whole plant is used.
2. Prior Knowledge of its Effects.
Dr. Roth has collected the following instances of its use.
1. Hippocrates used the plant mixed with alum as an application
to foul ulcers. (Opera omnia, Genev, 1657. De ulceribus, 879).
182 Anagallis-arvensis.
2. Dioscorides (lib. 2, cap. 174) says " that the Anagallis has the
power of mitigating and arresting inflammations. It draws foreign
substances out of the body and represses corrosive ulcers. Its juice
evacuates the brain of phlegm, if used as a gargle and discharged
by the nose. It relieves toothache if inserted into the ear of the op-
posite side. Used with Attic honey it cures spots on the eyes and dis-
orders of the sight. Infused in wine it is good for those who have
been bitten by serpents, and for those having diseased kidneys or liver.
The plant with the blue flower is said to cause the prolapsed rectum
to return, while that with the red is said to cause its descent by
rubbing."
3. Serapion (de simplicibus ex plantis, 1497, p. 119, CLV.)
endeavors to prove that the Arabian physicians used the remedy.
" Virtus ejus est quod calefacit partes et desiccat sine mordicatione.
Et secunda est quod abstergit et attrahit. Et tertia est quod extrahit
sagittas et spinas et alia infixa corpori. Et succus ejus injectus in
nares purgat cerebrum ab humoribus qui sunt in eo et incarnat ulcera
et confert corruptionibus membrorum."
4. Chomel (Histoire des plantes usuelles, Paris, 1*782, p. 276)
says " that it is useful in mania and epilepsy."
5. Hartmann, Mynsicht, Willis and others, also consider it useful
in the frenzy which comes on in continued fevers. It is employed by
the handful in the drinks and decoctions prescribed for hypochondriacs ;
water distilled from it has the same virtue. The alcoholic tincture of
the flowers, and the extract of the whole plant, especially if mingled
with the flowers of Hypericum, are remedies not to be despised in
epilepsy.
6. Tragus asserts that a glass of wine, which has been slightly boiled
with a handful of pimpernel, is a good remedy against the plague ; the
patient must keep himself well covered up in bed, the object being to
sweat him. He considers the juice good against dropsy, and renal
and hepatic obstructions.
7. Simon Pauli (Quadripartitum Botanicum, p. 196) mentions a
poultice of pimpernel boiled in urine as a popular remedy in his coun-
try applied to the hands and feet of gouty subjects.
8. Suadicani (Hufeland Jour. 44, p. 84), among others, has recom-
mended this plant against hydrophobia in a long memoir, which may
be referred to as above. It is a copious exposition of its efficacy
against hydrophobia, from the most ancient times to the present, and
maintains that the anagallis is as certain a therapeutic agent in canine
madness, as quinine in intermittents, or mercury in syphilis.
In addition to the authorities cited by Dr. Roth, we may add that —
9. Orfila found three drachms of the extract sufficient to destroy a
dog, with marks of inflammation of the bowels. The plant with blue
flowers referred to above is described by Linnaeus as A. coerulea, a
mere variety of the A. arvensis.
Anagallis-arvensis. 183
3. Digest of the Symptoms.
AUTHORITIES. Dr. Roth (Matiere Medicate 1, 251) cites
Schreter, Arch, horn., vol. 23, p. 174.
MIND. Moral. Great flow of spirits for several days ; everything
causes him pleasure. Hilarity ; more lively than usual ; he attends to
business with great pleasure and is very well satisfied with himself.
Mental* He is constantly thinking, his mind is very active.
HEAD. Forehead. Pressive aching in the sinciput from a current
of cold air. Temples. 5. Spasmodic lancinations in the temples;
from there they extend into the eyes, in the centre of which there is a
feeling of pressure.
EARS. Obstruction in the right ear, preceded by pressure upon
the eyes.
THROAT. Sensation of dryness and scraping in the throat.
STOOL. Desire to go to stool. Well digested stool - Rectum. 10.
Itching in the rectum and pressure on the sacrum as if from piles.
URINE. Urethra. Burning pain in the urethra when urinating,
especially in the morning ; the meatus seems stopped up ; he experi-
ences a strong pressure when the urine issues, and the stream divides
into two, three, or more jets. Tickling itching along the urethra, and
especially at the meatus, which is not very painful nor very disagreeable,
and which incites him to coitus.
GENITAL ORGANS. Coitus. Desire for coitus. Burning pain
in the urethra before coitus, and during the erection, which ceases dur-
ing the copulative act.
CHEST. 15. A sort of restlessness in the chest. Sensation in the
interior of the chest as if it were pricked by a great number of needles.
Heart. Violent trembling of the heart, with general trembling and
coldness, preceded and accompanied by a dull pain in a carious tooth,
and agitation in the chest.
BACK AND EXTEMITIES. Shoulder. Tensive drawing which
ascends from the left shoulder into the nape, and recommences after it
had ceased, whenever he raises and extends his arm. Metacarpus.
Dull drawing, sometimes tearing pain in the right metacarpus ; oftenest
on the right side, sometimes on the left, and returning at irregular
intervals. Finger. 20. Sensation resembling cramp in the right
thenar, when cutting with scissors, changing into a dull drawing ; when
it ceases on the right side it reappears in the same part on the left.
SLEEP. Bad, agitated night's rest ; he goes to sleep late, wakes
early, and desires to sleep still more in the morning.
FEVER. Heat. Heat rises into his head, and he _ experiences a
slight sweat on his forehead, followed by a pressive lancination in the
globes of the eyes, and a tickling formication in the urethra exciting
him to copulation. Cold. Trembling and chills.
184: Ajpis-mellifica.
6.— APIS-MELLIFICA,
APIS. The common honey-bee.
We are principally indebted for the proving of this very admirable
remedy, to the indefatigable zeal and perseverance of our colleague, Dr.
F. Humphreys, of Utica. Having been experimented upon by him, he
proposed it for trial to the Central Homoeopathic Society of New- York,
upon which a committee was appointed to prove the drug and report
upon it. Drs. Bishop and Munger were joined to Dr. Humphreys, and
the result was a report to the Central Society which is incorporated in
the following article.
1. Description and Preparation.
This useful insect is too well known and too widely diffused to need
a particular description. It and its products, honey and wax, have ap-
parently been familiar to man from the very earliest ages.
The preparation with which the following provings were made was
procured by placing the living working bees, taken in the month of
August, in a large open-mouthed vial, and pouring alcohol over them
when in a state of excitement. The tincture is suffered to stand
awhile, and is then decanted clear for use.
Dr. Hering suggests that a better mode of procuring the pure virus
of the insect, would be to seize the bee by the head and with a little
forceps extract the sting and poison bag together, which may then be
triturated with sugar of milk.
A preparation has also been obtained by placing the living bees in a
closed vessel until they were suffocated and dried, and then pulverising
them with milk-sugar.
2. Prior Knowledge of its effects.
That the bee possessed a powerful weapon of offence in its sting,
and that the effects arising from its delicate puncture were sometimes
formidable, has always been known, but from the want of a true thera-
peutic guide, this knowledge could never be made serviceable in the
cure of the sick.
1. Deseret relates that a workman fifty years old was stuno- by a
bee over the right eyelid ; he immediately fell to the ground and in a
few moments died. His face was inflamed, and after death there was
a copious discharge of blood from the nose.
Apis-mellifica. 185
2. Zacutus saw, after a sting in the eyebrow, an inflammation, vio-
lent pain and gangrene of the part follow.
3. In a Munich Journal, a case is related where a man was overtaken
by a swarm of bees and so stung in the hands and face, that he soon
died from the pain, inflammation and swelling of the affected parts.
4. " The poison-apparatus is found in the females and neuters only.
It consists of two thin convoluted secreting organs, opening into a pyri-
form receptacle, from which a small duct passes to a sting which con-
sists of two portions, placed side by side, barbed at the extremity and
contained in a sheath. The poison is said to be hot and acrid to the
taste. The consequences produced by the sting of a bee are pain, red-
ness, swelling and hardness of the part ; and might prove fatal if a
swarm were to attack an individual." (Pereira).
5. Mr. Lawrence mentions the case of a French gentleman, who was
so severely stung by bees about the upper part of the chest that he died
in fifteen minutes, with all the symptoms of mortal collapse usually pro-
duced by the bite of venomous serpents. (Med. Gaz. 5, 582.)
0. Dr. Marcy (Theory and Practice, 54*7) states that the first tritu-
ration of the honey-bee has proved successful in his hands in ascites
and hydrothorax. " In large doses, it causes a sense of fulness, con-
striction, or of suffocation in the thorax ; difficult and anxious respira-
tion ; pain and tenderness of the abdomen, increased by pressure or
contact, symptoms worse in the horizontal posture ; great secretion of
urine, which is pale or of a straw color, and deposits a reddish or brick-
colored sediment ; frequent desire to urinate, and strangury." After
citing a case of ascites, which will be found under the clinical remarks,
he adds : " "We have witnessed the effects of this remedy in two other
cases of ascites, in one case of protracted general dropsy, and in one case
of hydrothorax, and with the same favorable results. The powder of
dried honey-bees has long been used as a remedy in dropsies by the
aborigines of our country."
7. A lady, aged 65, had been in the habit of attending and taking
care of honey-bees for forty-five years, had been frequently stung, and
always with but slight inconvenience. In September, 1849, her atten-
tion was directed to some apj^les, which were drying, among which some
bees were present, when one of them stung her on the chin. She
hurried into the house, remarking that a bee had just stung her, and
that she "felt strangely," which were her last words. In less than fif-
teen minutes all signs of life had disappeared. — Amer. Magazine.
3. Digest of the Symptoms.
AUTHORITIES. 1. Dr. Barker. 2. Dr. Bigelow. 3. Dr.
Bisnop. 4. F. D. 5. Dr. Greene. 6. Dr. Hays. 7. Dr. Hum-
phreys. 8. Dr. Kellogg. 9. Dr. Munger. 10. Dr. Robinson.
11, Dr. Wells.
The figures at the end of the symptoms refer to the authority ; the ordinary
type indicates the pathogenetic effects ; the symptoms which have disappeared un-
186 Apis-mellijlca.
der the use of the drug are distinguished by a cypher (°), and those which have
been confirmed by cures are preceded by an asterisk (*).
MIND. Irritable disposition the eighth day ; nothing appeared to
satisfy him, all out of place (7.) Unfitness for mental exertion (7, 11).
Dread of death, or sensation as if he should not be able to breathe
again (2).
_ SENSORIUM. Confused vertigo for several days, at times very
violent, worse when sitting than when walking, and extreme when lying
down and on closing the eyes, from several doses of the 30th (7).
5, Head is dull and slightly confused (7). ° Crazy, wild, blind staggers
in horses (old observation) 7. Furious mania ? (7).
HEAD. Weight and fulness in the upper part of the head (2
Heaviness and pressure in the head, continued three or four days, com-
menced one hour after taking one drop of the 3d att. (11). °Great
sensation of rush of blood to the head (3). 10. Headache over the
eyes, which is dull, heavy, tensive, with pain through the orbits, lasting
but a short time; this headache has occurred in three provings ( )l
°Semilateral headache over and in one eye and in the whole left side of
the head, with redness and puffy swelling of the cheek, nausea and
vomiting (6th dil.) (4). °Headache on the right side, involving the eye
and side of the head ; must keep the eye closed ; pain very severe, com-
ing on at 10 or 11 a.m., and continuing until night; cured by 6th dil.
(7). * Chronic headache in nervous subjects ; violent pain in the fore-
head and temples, at times involving the eyes, attended by vertigo, nau-
sea and vomiting ; must hold the head and eye down (7). 15, Pressing
pain in the sinciput with vertigo, immediately (7). *Pain in the sinci-
put and confusion of the head (7). *Disagreeable headache in the sin-
ciput (7). Sensation of dulness across the forehead just over the eyes,
third day (8). * Violent headache, mostly confined to the forehead, with
fever, second day (2). 20.*Burning and throbbing in the head aggravated
by motion and stooping, temporarily relieved by pressing the head
firmly with the hands, with occasional sweat for some hours (2.) Dull
pressive headache in the upper part of the forehead as if it would burst,
extending to the temples (11). * Violent pressive pains in the forehead
and temples for several days (7). *Dull, heavy headache on rising, con-
tinued till 3 o'clock p.m., second day (11). Oppressive headache when
in a warm room and reading (2). 25. Boring pains in the temples,
continued for several days at intervals, lasting only a few minutes at a
time, commencing the third day, after taking 3 drops of the third att.
every morning (11). *Slight aching in the left temple (7). *Violent
sharp pain in the left temple (7). Violent aching pains through the
temples, and organs of causality, comparison, mirthfulness, and ideality
(2). Boring pains in the temples every morning on waking, for three
mornings (11). 30. Dull heavy pain in the right temple on waking in the
morning, soon changing to the left, first day (11). Throbbing, painful
sensation in the temples (3). °Sharp pricking pains in the temples and
across the forehead (3). Dull ache in the occiput (6). Aching in the
Apis-mellifica. 187
occiput increased by shaking the head (7). 35. Slight pressure in the
occiput (7). Sharp tensive pain from the neck up back of the left ear,
extending forward over the left side of the head, first day (7). Head-
ache with fulness and heaviness in the occiput (7.) Falling out of the
hair all through the proving.
EYES. Transient biting itching in the right, and sometimes left
eyebrow (7). 40. *Burning stinging in the right eye, commencing
with a dull heaviness and causing flow of water ; twice repeated (7).
* Stinging itching in the eye, eyelids and around the eyes, on the left
side, and more at the internal canthus (7). Itching of the right evelid,
continuing all day at intervals. (This symptom repeated in several
provings) (7). *Itching and prickling of the lids of the right eye, 1st
day (11). Violent stinging in the lower right eyelid, in the morning
(7). 45. Burning stinging and sensation of swelling around the left
eye, and in the superciliary ridge (7). *Pain around the orbits of the
e y e CO- "Pricking sensation as if from a foreign body (3). Aching
pressure in the orbit of the left eye, mostly the lower portion, continuing
for several hours ; twice repeated (7). *Slight agglutination of the
eyes at night; had to pick them open in the morning (7, 11, 6). 50,
Sensation as if there was a mass of mucus in the left eye, continuino- all*
day (7). Flow of mucus and lachrymation of the right eye at night in
bed (7). °Soreness, redness of the eyes and eyelids, secretion of mucus
and agglutination of the lids, attended with nettlerash over the surface
(7). °Styes (7 et al). °Soreness of the margin of the lids and can-
thus (7). 55. "Erysipelatous inflammation of the eyelids (7). A
sensation of whirling around in the sight, with difficulty of seeing at the
same time, lasting only for a moment (2). *Dull, heavy feeling, incli-
nation to close the eyes, desire to rub them forcibly, making pressure
with the fingers when closed for some time (3). * Weak eyes ; for
several days the light is painful (7). The eyes are weak, and an indis-
position is felt to use them ; they are painful and easily fatigued when
employed ; only regain their strength and vigor the 10th or 12th day;
this was experienced by one who had never had weakness of sio-ht
before or since (7). 60. Tremulous twitching in the left eye, more at
night, and continuing for several days (7). inflammation of the eyes
and lids attended with burning and biting pains and itching ; manv
cases (11). °CEdematous swelling of the eyelids (7). ° Smoky opacity
of the cornea, occasioning almost entire loss of sight ; several cases (7).
"Opacity of the cornea with congestion of the sclerotica, obscuration of
sight of several months' duration (11). 65. inflammation of the
cornea (7).
EARS. Burning of the superior portion of the left ear (7).
NOSE. Violent sneezing immediately (7). Frequent sneezing for
many days, eleventh day, in two provings (7).
FACE. Sore elevations like the sting of insects, very tender to the
touch, at the external corner of the eyebrow (7). 70. Burning stinging,
as of fire, on the chin and malar bones (7). Burning stinging at the
left superciliary ridge (7). Swelling of the lips, and sensation of
188 Apis-mellifica.
swelling for several days, followed by a fine eruption around the lips,
and dryness and peeling off of the lower one (7). Roughness and
feeling of tension in the lips, especially the upper one (7). Dark streak
along the epithelium of the lips, they are rough, chapped and peel off
(7). 75. Prickling in the lips, and sensation as if they had received
a severe contusion, with sensation of swelling; in a few hours (7).
"Burning, biting, stinging heat, assuming a purplish hue, in about 24
hours (3). "Erysipelas of the entire face, with light redness, swelling,
heat, burning fever, coated tongue and thirst ; in a girl of 9 years, cured
by the 6th dil, every 4 hours (7). "Erysipelas of one entire side of the
face and nose, swelling under the eye, resembling that from a sting,
cured by the third att. in water, rapidly and permanently (5).
TEETH. Jumping pain in the superior molars of the left side (6).
MOUTH AND THROAT. 80. Contraction and erosion in the
throat in the morning (7). Extreme sensation of rawness and scalding
all around the margin of the tongue, as if it had been scalded, and
slight pimples on the edge from taking the tincture, at 4 hours (7).
Increased feeling of contraction in the throat, rendering deglutition
difficult, at 8 hours (7). *Rawness, burning and blisters along the edge
of the tongue, which are very painful, accompanied with stinging, at 8
hours, from the tincture (7). Scalding of the mouth and throat for two
days (7). 85. Stinging itching deep in the throat at the lower part of
the neck, accompanied with a sensation of constriction (7). Great
accumulation of viscid mucus deep in the throat in the morning, which
requires repeated hawking, eleventh day (7). Dryness and heat in the
throat, first day (11). Dryness in the mouth and throat, the tongue
feels as if burnt, second day (11). Prickling heat on the tongue, 1st
day (11). 90. Sensation of dryness in the mouth and throat, 2d day
(11). Copious accumulation of'Soapy saliva in the mouth and throat,
in the morning, second day (41). ' "Burning stinging sensation in the
mouth and throat (3). *Dryii^S of- the tongue, red, fiery appearance
of the buccal cavity, with pamful tenderness (3). An aching pressure
as if from a hard body, back in the upper part of the throat and fauces,
continuing for some, hours, at half an hour. (Occurred in two provings)
(7). 95. "Very appropriate in various kinds of angina, with redness,
swelling, and stinging 'pains (7). *Glossitis.
APPETITE AND STOMACH. Violent eructations (6). Eruc-
tations, tasting like the yolk of eggs (6). Nausea, apparently from the
throat. (0). 100. Nausea and inclination to- vomit at night, and disa-
greeable rumbling in the abdomen as if a diarrhoea would come on
(7). Prickling pain in the stomach, as from needles (6). Sensation
of heat aaab burning in the stomach 1st day. (11). "Bilious vomiting
with a single dose in 15 to 60' mhmtes, 4 dasete ('3).
ABDOMEN; Aching and prising pain in the hypogastrium, with
beaiag.gdowin.iW" ! tlheO\ite)M m if the menses' would come on i'n two
persons #«}§ . 105^ Rwnlblifi(g)in the aWhnneti, as if diarrhoea would
ensue .((J).- n Soio freliilg in4htoadmen In tlW meming (6). Sickly
feeling in the abdomen which disposes a person to continue in a quiet
Apis-mellifica. 189
sitting posture (6). Dull pain in the bowels (6). Soreness of the
bowels felt when sneezing or pressing upon them (6). HO. Fulness
and evident enlargement of the abdomen, from many and large doses,
in a female (7). Fulness and sensation of bloating in the abdomen
as if she were puffed up (7). °Ascites following enteritis ; abdomen
distended with serum ; countenance sunken, pale, sickly ; urine scanty,
high colored ; pulse quick, wiry ; deficient appetite (5). Has proved
curative in several cases of ascites (7). Enlargement of the abdomen,
with swelling of the feet and scanty urine, in a lady of fifty (7).
ANUS AND STOOL. 115. Sensation of stuffing in the anus (6).
Throbbing in the rectum (6). Heat in the anus (6). Loose lumpy
stool (6). *Loose stool in the morning (7). 120. Loose, urgent stool
in the morning (6, 7). Bowels confined from the 8th to the 12th
day (7). Stools soft and pappy, mixed with serum, as though soft
fseces had been beaten in water but not dissolved ; the color that of an
orange (8). Loose stools eight days in succession (11). Several loose
stools daily (7). 125. Several loose yellow stools, with extreme weak-
ness and prostration ; stools coming on at every movement of the body
as though the anus were continually open ; in a lady of 40 affected
with chronic ascites, from the 6th dil. (7). Two loose stools daily for
five days (11). °Painful diarrhoea (3). Yellow, watery diarrhoea,
griping, 12 movements in as many hours (3). ^Frequent yellow,
watery evacuations, from a single dose (3) ; several other similar
cases. 130. Hemorrhoidal affection with constipation, small tumors
upon the verge of the anus; biting, boring, stinging pain, indescribable,
insupportable, with extreme nervousness and irritability ; pain relieved
in 4 hours, cured in 24 hours (3). °Involuntary dark bloody oozing
from the rectum, with swelling of anus (3). ° Hemorrhoidal tumors
attended with soreness and burning, stinging pains (3, 8, 11, et al).
Sensation in the rectum resembling an electric shock, slightly painful,
succeeded by urging to stool (6). Stool natural, preceded by emission
of flatulence and a small quantity of almost colorless water, containing
lumps or fragments of jelly-like mucus, streaked with blood (6).
URINE AND GENITALS. 135. Repeated urination every few
minutes, continuing through the entire day, in a person never subject to
such attacks. The medicine, 1 drop, 2d, was taken at night, the symptoms
appeared the day following (7). Frequent and excessively profuse dis-
charge of natural urine through the clay and night in a dropsical and
pregnant subject, from 3 doses of the 30th (7). Frequent and copious
discharge of urine (7). Somewhat frequent desire to urinate, attended
with uneasiness in the spermatic cord, fifth day (8). More frequent
inclination to urinate, attended with some burning before and after
emission, second day (11). 140. Urine high colored with more fre-
quent emission, small in quantity, third day (11). Burning in the
urethra before and after urination, third day (11). A pustule sore as
a boil, surrounded by a red areola, and maturated in the centre, arises
in lln- hair of the pubes, remaining sore and painful some days (7).
Urine scanty, with burning, smarting pain ; several cases (3).
190 Apis-mellifica.
Stitch-like pain in the urethra (6). 145, Frequent desire to urinate,
attended with burning in the urethra with uneasiness in the spermatic
cord, sixth day, from large doses (8).
MENSTRUATION. Bearing down pains and sensation as if the
menses would come on, in many cases (7). Bearing down pains as in
the early stages of parturition, in several cases (3). Bearing down
pains in the uterus as if the menses would come on, with aching and
pressing in the hypogastrium (7, 11). Metrorrhagia at the second
month with profuse flow of blood, heaviness of the abdomen, faint-
ness, great uneasiness, restlessness and yawning (7). 150. Hemorrhage
from the uterus, occurring in a lady who was always regular and
healthy, occurring one week after the cessation of the usual menstrual
period, and three days after taking the medicine (7). Miscarriage at
the second month ; from drop doses of the second dilution (7). Mis-
carriage at the third month (7). Miscarriage at the fourth month in
a healthy young married female during an attack of mild fever; on
giving Apis 6, abortion came on, attended with profuse flooding (3).
Should only be given to pregnant females with the utmost caution (7).
°Amenorrhoea in young girls ; many cases (7 et al.). '^Suppressed men-
struation, many cases (7 et al.). °Great increase of pain and tenderness
in the ovarian region in two cases, one of large induration, the other in
a supposed incipient stage of development (3). °Has proved curative in
several cases of enlarged ovaria and also in ovaritis (7, 11). Ovarian
dropsy ? (7).
LARYNX AND COUGH. 160. Hoarseuess and rough voice
through the day and night, second day (7, 6).
CHEST. Pressure in the chest, soon (7). Sharp pains in the chest at
night (7). Stitches through the chest and back at night, *Stitches in
the left side of the chest (6). 165. Several stitch-like pains just below
the heart (6). Hurried and difficult respiration with fever and headache,
second day (2). Pain near the heart, which almost arrested the breath-
ing at night, continuing at intervals for some days (11). Sensation as
though he should not be able to breathe again (11). Short rapid
breathing at night (2). 170. Sensation of warmth or burning in the
chest, first day (11.) Pains as of a bruise, and sensation of weight in the
chest for several days (7, 3.) Sensation of fulness, tension and pressure
in the chest, first day (11). Dull aching pains in the left side of the
chest near the middle of the sternum, several times during the day, with
sensation of fulness in the chest, with short breath first day (11). Sen-
sation of burning heat in the chest and stomach early in the morning,
second day (11). 175, Sensation of soreness, lame, bruised feeling, as
if from recent injury from being jammed, bruised or beaten ; confirmed
in many provers (3). *Sensation of melting heat in the region of the
diaphragm, as if from running violently (3 et al.). Slight oppression of
the chest, with frequent desire to draw a deep inspiration (6). Slight
pain in the left side of the chest under the short ribs (6). °Has proved
curative in hydrothorax, in several cases (7, 11).
Apis-mdlijicn. 191
BACK AND NECK. 180. Rheumatic stitches in the muscles of
the right side of the neck, worse when moving the head in that direc-
tion, came on when rising in the morning, very painful ; not so much
noticed when moving the head in any other direction, second day (7).
Tension in the right side of the neck, beneath and back of the ear, soon
(7). Sudden flush of heat over the back, as though sweat would break
out, accompanied by a pain at the left ileo-sacral junction (3). Dull
pressure under the scapula, with sore feeling on moving the parts (6).
Slight sensation of stiffness in the nape of the neck and small of the
back (6).
SUPERIOR EXTREMITIES. 185. Aching in the right shoulder
and upper portion of the arm, soon (7). °Erysipelas of the left arm and
wrist, with redness, swelling, heat, and tumefaction of the part ; cured
with Cth dil. (7). Burning as of fire in small circumscribed spots on
the hands, continuing for some minutes, second day (7). Fiery burning
at the points of the finger (7). Tingling of the fingers of the left hand,
soon (7). 190. Darting pains in the left elbow for an instant, third
day (8). Great increase and intensity of the odor from the axillary
glands, fourth day (8). Dull pains apparently in the bones of the
arms and fingers (6).
INFERIOR EXTREMITIES. Fine burning stinging on the knee
(7). Darting, transient pain in the external malleolus of the left ankle
for four days (8). 195. Dull pains as if in the bones of the lower ex-
tremities (6). Sore feeling of the flesh of the lower extremities, disap-
pearing on walking, returning again while sitting (6). Burning of the
toes and redness like erysipelas and heat of a circumscribed patch on
the foot, while the remainder of the feet are cold ; continuing half an
hour (7.) At night, on removing the boots and socks, the feet were
found swelled full, with a sensation of heaviness and rigidity, the upper
part of the feet felt bungling and itched, and were of a bright red color.
The soles of the feet and balls of the toes had a feeling of painful fulness,
and in walking gave the sensation as if cushioned ; sixth day, as from
many large doses (8). Burning of the feet, first day (11). 200. *03de-
matous swelling of the extremities (7).
SKIN. *Prickling all over the body, most on the back and palms
of the hands, the face, forehead, and under the eyes, mostly in circum-
scribed points, immediately on taking the drug (6, 7 et al.) *Erup-
tion resembling nettle-rash came out all over the body of a man, soon
after being stung (7). °Nettle-rash in a lying-in woman (7). °Large
hard elevations like mosquito bites, upon the back and legs of a child,
accompanied with stinging, itching and burning (7). 205. *Blotches
on the body and back of the hands, attended wilh stinging like nettles,
second day (11). Portions of the surface as large as a dollar swell up
without discoloration, and become excessively sore and tender to the
touch ; 1st att. and tinct. (7). Itching pricking in the skin on differ-
ent parts of the body, more on the lower extremities, and continued
through the day, 1st day (11). °Eruptions upon the whole surface of
the body somewhat resembling measles, with great heat and purplish
192 Apis-mellifica.
circumscribed hue upon the cheeks (3). Eruption like nettle-rash over
the whole body, second day after taking the 30th att., attended with
burning and itching (11). 210. Retrocession of eruption in scarlatina,
with violent fever, extreme heat, injected eyes, congestion to the head,
and violent delirium continuing for many hours ; aeon., bell., bry. and
other remedies did no good ; apis every three hours brought out the
rash, relieved the congestion and delirium, and cured the case (10).
°A ringworm on the neck of a girl aged 12, inflamed and excoriated by
the clothing, with one dose 30th att. (11).. *Sensation of burning heat
and stinging in various portions of the surface of the body, at the same
time (3). The entire surface becomes exceedingly tender to the touch;
every hair is painful on contact, from 6th dil. (7). °Hard, livid pur-
plish tumors, or small elevations upon the forehead, face, and lower
limbs (3). 215. * Furuncles, and large swellings of every descrip-
tion, or local inflammations attended with them, and accompanied with
stinging pains (7 et mult. al). *Nettle-rash in numerous instances
(7 et mult. al.). *CEdematous swelling of the extremities (7 et al.).
°Pufly swelling of the face, hands, forehead, temples, about the eyes,
neck and upper arms, with inability to swallow food, nasty taste in
mouth, fever, thirst; can drink water constantly; commenced with a
violent shaking chill : cured with apis 30, then 6, every three or four
hours (7). °Post-scarlatinal dropsy, several cases after ars., bell., dig.
and aeon, had failed (9). 220. ° Anasarca and ascites after scarlatina
(7 et al.-).
SLEEP. *Fidgetty restlessness in the latter part of the night (7).
Fidgetty restlessness the entire night with inability to sleep (7). Night
sleep is full of dreams (7); this symptom repeated in every proving.
Night sleep is yet full of dreams, mostly of travelling, eleventh day (7).
Disagreeable dreams about fiends (11). 225. Frequent waking, first
night, and dreams with vexatious cares about various kinds of business
(11). Sensation as of movement from place to place, mostly travelling
by railroad (11).
FEVER. Pulse 95, full and strong (2). Pulse increased 20 in a
minute, full and strong, second proving (2). Sweat breaks out occa-
sionally (2). 230. Sweating and dryness of the skin, alternately (2).
Occasional feeling of chilliness (2). Inclination to yawn (2). Slight
chill soon passing off, followed by fever at night (2). Pulse accelerated,
first day (11). 235. Heat at night with agitation, first night (11).
Pulse increased from Go to 77, first clay (11). General feeling of heat,
worse in the chest and stomach, first day (11).
GENERALITIES. General feeling" of lassitude, second day (11).
General feeling of lassitude with trembling (11). 240. Sudden pros-
tration of the vital force, severe vomiting, profuse diarrhoea, cold extre-
mities, paleness of face, severe griping pains in the abdomen, pulse
feeble, scarcely discernible at the wrist; no redness or pain in the part
stung. [From a sting on the eyebrow.] Apis-mel., 3, 5 gib., and
not repeated; reaction came on in 10 to 15 minutes; improvement
continued ; some redness of the part stung appeared on the abatement
Ajpis-mellifica. 193
of the general symptoms (3). Bruised sensation all over him, sides,
hips, back, everywhere, restlessness the whole night and loose urgent
stool ; in the morning from some pellets of the 6th dil. taken over night
for a stye : this train of symptoms repeated 2 or 3 times from similar
doses (7).
4. Clinical Remarks.
Case 1. The following case of involuntary proving of the Apis is
reported by Dr. Bishop.
Mrs. R., aet. 40, unmarried. Large Ovarian Tumors. Left tumor press-
ing upon the rectum, interfering with defecation — should think them four
inches in diameter, extremely hard to the touch per vaginam and externally
— of three years' standing, having been suddenly developed by a powerful
emmenagogue. General health not good ; subject to nervous headache.
At the time she came under my care, July 13th, 1850, she complained
much of sharp, lancinating pains in the ovarian tumors ; urine scanty ;
bowels constipated ; but no headache or fever. Failing to relieve the lan-
cinating pains in the tumors as I had done before with Lachesis, followed
by Plalina, and not succeeding with any other remedy to my liking, I left
3 drops of Apis-met. 2 ; also the same quantity of the first dilution, directing
her to take the first dilution if she received no relief from the second, but if
any aggravation occurred to stop the medicine, immediately. The symp-
toms which I will now detail and which I consider pathogenetic, began to
be developed before she had taken of the second. But as she had always
been notoriously faithful in taking allopathic remedies, come what would,
and as my next visit was deferred nearly two days beyond the time I in-
tended, she had taken all the medicine left her.
Symptom*. Head. — General headache, very severe, with great
sensation of pressure or rush of blood to the head. Throbbing, painful
burning sensation in the temples.
Eves. — Smarting burning sensation, great redness of conjunctiva,
very sensitive to the light.
Face. — The patient seemed at a loss for language to express the
peculiar burning and heat in her face experienced during the first 24
hours of its continuance ; a somewhat livid and purplish appearance
came on upon the abatement of the heat and burning.
Chest. — Nothing of importance developed in the air passages, but
some portion of the respiratory muscles, including the diaphragm and
mediastinum, indicated a specific impression from the drug. She felt a
severe burning pain under the short ribs on both sides, most severe on
the left and of longer duratiou, continuing in the left side more than
two weeks, and so severe as to deprive her of sleep nearly the whole
time.
I will endeavor to describe the kind of heat and burning which,
according to my own experience and the testimony of others, may be
regarded as a specific and pathogenetic symptom of the Apis-mellifica.
1. On the surface like the sting of bees, or rather the burning heat
which follows the introduction of the virus. 2. Upon the serous mem-
branes and muscular tissues, especially in the region of the diaphragm,
194 Apis-mellifica.
the pathogenesis of Apis-mel. is best described by the peculiar sensation
of heat or melting, if I may be allowed the term ; a sensation sometimes
experienced after running violently, so that one is obliged to sit down
exhausted, and in common parlance, feeling as if his vitals were liter-
ally melting. 3. Somewhat resembling the effects of arsenicum, so far
as the mere sensation of heat is concerned, but with actual heat, in
addition, and a livid purplish hue.
Stool. — Greenish, yellowish, slimy diarrhoea, perfectly painless,
coming on in about 24 hours after taking the first dose; she had 12
movements during the day ; never subject to looseness of the bowels,
and never had anything in her life resembling it. The diarrhoea
subsided after one day's continuance.
Urine." — Diminished in quantity one half, although scanty before
taking the medicine; the scalding burning sensation was very severe
while urinating.
Fever. — The development of heat and fever, which I regarded as
pathogenetic in this case, continued to increase for about 36 hours, and
was then followed by a severe shaking chill, occurring about 5 o'clock
in the morning ; she felt very cold, but was not actually so to the touch
of another person.
General Remarks. — The pain in the ovarian tumors was much
diminished in a day or two, and at the end of two weeks she had not
much disturbance from that source. I was wholly unable to control the
heat and burning pain in the left side, though I made an effort to do
so for about ten days, at which time she took, on her own responsibility,
a large dose of epsom salts and soon after was bled, but with no benefit
or abatement of the symptoms. After waiting rather patiently against
time for improvement, she so far recovered as to visit relations at some
distance, which, I must confess, somewhat relieved me, to say the least,
from positive proximity to the subject of experiment with Apis-
mellifica.
The following examples of the clinical use of the Apis have been
furnished from various sources.
Case 2. Ascites ; reported by Dr. Barker.
A gentleman of 70, feeble constitution, lymphatic temperament, light,
skin, blue eyes, was seized, after an attack of influenza, with dropsical swell-
ing of the chest, abdomen, feet and legs. He was unable to lie down
without panting, and was always worse towards morning ; urine reduced
to a half pint per day. Apis 3 (dec. dil.) ; after three days the urine be-
fan to flow freely ; between 3 and 9 a. m., two quarts would frequently be
ischarged, and under the use of this remedy, subsequently alternated with
Ars. 60, the patient entirely recovered.
Case 3. Ascites ; reported by Dr. Greene.
W. C, set. 3£ years. Abdomen very much distended with serum,
countenance sunken, pale, sickly, pulse quick, rather wiry, appetite poor,
urine scanty and high colored. He had an attack of enteritis in Septem-
ber last, from which he rapidly recovered. I supposed that to be the cause
of the present difficulty. I administered in their turn ars., dig., dulc, mere,
Apis-mellijica. 195
china and sulph., but with no decided effect. The effusion still continued
to increase up to Feb. 10th, at which time there was much difficulty of
breathing except in nearly an erect position. At this time I performed the
operation of paracentesis, drawing off some 7 or 8 lbs. of a dark, sizy,
muddy looking serum. I then gave one drop apis three times a day, for
five or six days, with two doses mere, sol, intermediately, at which time
the urine became more free, although there had been some more sensation
of fluid in the abdomen during that time.
Finding the quantity of urine increased and the general symptoms better.
I gave 4 or 5 pellets of apis, 3, three times a day, and continued that treat-
ment five or six days, his health still improving. I then reduced it to twice
a day, which he has continued to the present time ; there are now no drop-
sical symptoms and the boy is lively, appetite good, bowels regular and
every way in a promising condition for perfect health. Repeated med. only
every third night.
Case 4. Ascites ; reported by Dr. Humphreys.
An elderly lady of light complexion, lymphatic temperament, had long
suffered from dropsical swelling of the abdomen and extremities. The
ankles and feet were quite oedematous and clumsy, the urine scanty .and
high colored, and she suffered from general depression and weariness. She
had used several remedies to no purpose. Apis-mel. 30, rendered prompt
and decided service, and has since always relieved her when from extra
fatigue or other cause the dropsy has manifested itself.
Case 5. Ascites ; reported by Dr. Marcy.
The following case occurred in the practice of Dr. Taft of Hartford,
Conn. : The patient, a boy of 12, was attacked in July, 1849, with dysen-
tery. After several weeks of medication under an allopathic physician,
the acute symptoms subsided and the evacuations gradually assumed their
natural state, but there remained an unnatural fulness and tenderness of the
abdomen, some difficulty of respiration, especially on assuming the recum-
bent position, a dry and harsh skin, and a materially diminished secretion of
urine. Notwithstanding the persevering employment of the usual allo-
pathic routine of cathartics, mercurials and diuretics, the patient continued
to grow worse, his abdomen became very much distended with serum, and
very tender to the touch, or from even the pressure of the bed clothes; the
respiration became exceedingly laborious and difficult, obliging the sufferer
to remain for a good portion of the nights in his chair ; impaired appetite, an
almost entire suppression of urine, emaciation, debility, small and rapid
pulse, anxious expression and other signs accumulated.
In this condition he came under the care of Dr. Taft, who administered
dig., ars., dulc, mere, chin., sulph., hell., but without amelioration. In the
meantime, the increasing difficulty of respiration, loss of rest, of appetite
and pain, had reduced the patient to so serious a condition that I was called
in council with Dr. Taft in order to decide respecting the propriety of tap-
ping. In consideration of the urgency of the symptoms and the ineffici-
ency of the remedies which had been used, I evacuated the effused fluid,
amounting to sixteen pounds, and advised a second trial of arsenicum and
digitalis. No effect resulted and there began to be signs of thoracic effu-
sion. Recourse was now had to the first trituration of the honey-bee,
(5 to 100), and after two or three doses a large quantity of urine was pass-
ed, and the symptoms were all ameliorated. After the remedy had been
continued for two weeks, all traces of effusion disappeared, the appetite
196 Apis-7nellifica.
and strength began to improve and the respiration became natural and
easy. The patient was restored to perfect health.
Case 6. Asthma ; reported by Dr. Wells.
Mr. N. P., aet. 70, had shortness of breath, oppression of the chest on
taking an inspiration, and sensation of heat in the chest. These symptoms
had been gradually increasing several weeks. Took apis 3, once a day,
and was completely relieved in one week.
Case 1. Bronchitis ; reported by Dr. Bishop.
Mary C, jet. 2 years. High fever, hot, dry skin, full pulse, laborious
respiration resembling croup, painless diarrhoea, yellowish, sometimes
greenish and slimy, tongue slightly coated white, disturbed sleep at night
with muttering, incoherent talking. Gave aconite, bry., hep. and other
remedies, for three days without any benefit. Respiration very laborious,
requiring unusual aid from the abdominal muscles ; face flushed with in-
creasing livid appearance. Fourth day; pulse not as frequent, but feeling
under the finger like shot or some spherical body, gliding along the artery ;
cough attended with the ringing sound peculiar to affections of the upper
portions of the respiratory tubes. Prognosis unfavorable, deeming it
probable the patient would die in spite of all my efforts. Left her three
doses of apis 3. Next day found her much better, face natural, pulse much
improved, fever nearly gone, appetite improved, had slept well and without
the usual mutterings, fright, &c. Continued the medicine in diminished
doses, and next day found her so much better that I dismissed her as cured.
Case 8. Cephalalgia ; reported by Dr. Bishop.
S. A. W., set. 36. Took one drop of apis for periodical headache, with
direction to repeat ad libitum. The first dose promptly suspended a
paroxysm in its incipient stage. No homoeopathic remedies had ever before
had any effect in stopping his headache. The same result was obtained
the second and third time. He then requested a supply of the remedy to
be used as occasion required, which was furnished him, with directions not
to use too much of it. This advice he did not heed. He got an aggrava-
tion of his complaint, and at length developed in his chest the true patho-
genetic symptoms of the virus, viz. : sensation, as of having been bruised,
jammed or beaten.
Dr. Kellogg has given the apis with decided benefit in the case of a
female who had suffered for years under symptoms of general prostra-
tion, particularly in cold weather, attended by asthmatic symptoms, as cough,
choking pain in the chest, with coldness and deadness of the extremities,
and purplish livid hue. Also, in some cases of "chronic sick headache,
where there seemed utter prostration of the central ganglionic nerves.
Case 9. Diarrhoea ; reported by Dr. Bishop.
J. M. B. Sept. 1st., 1850. Yellowish, greenish diarrhoea; some griping
pain; pain in the eyeballs and across the forehead, more on the right side
for some years past, but formerly in both temples alike, languid, listless, un-
accountable feeling. A year ago had partial development of intermittent
fever. At the time, said he had " the blues." Could not bring his thoughts
to bear upon anything definitely. Hands bluish, inclined to coldness; ap-
petite poor. Was promptly cured of all these symptoms by a single dose
of apis 3.
Apis-mellifica. 197
Remarks.— The action of Apis-mellifica in the case of Mr. Butler (a
single dose) remained about two months, and then the symptoms seemed
to require its repetition. A single dose relieved him as before, and he had
no occasion for repeating it for four or five months. A single dose has al-
ways been sufficient for him, and in no case do I recollect the improvement
which set in, to have continued for less time than two months. Mr. B. is
23 years of age, light complexion, spare and thin, muscular power not
great, uses a good deal of tobacco.
Case 10. Diarrhoea chronic ; reported by Dr. Bishop.
J. S., set. 6 years. Chronic diarrhoea and general emaciation. Sequelae
of measles. In this case there had been only a partial development of
measles upon the surface, attended with fever and cough for two months
and then general emaciation, with tenderness of the bowels, loss of ap-
petite until he was reduced to a mere skeleton. He then received from me a
few drops of apis, which immediately improved his appetite, bowels became
regular, his flesh returned, and he continued quite well for some months.
Dec. 28th, 1850, saw him again; dry white tongue, loss of appetite, fever-
ish heat during the night, and other times pale, emaciation going on. A
few doses of the same remedy again set him right.
Saw him again about the 1st of January, 1851, and, at the request of his
mother, left him a number of doses of apis, in case he should need it at
any time in future. He soon after got a dose and grew worse, got another
and then another, resulting in the development of a tumultuous action
which, for nearly 24 hours, seemed to threaten his life. At this time I was
from home attending the meeting of the Central Association, at Utica, and
did not see him until the paroxysm of excitement had nearly subsided.
From his mother I learned the following particulars of the case: general
heat and redness of the surface, like scarlet fever, with some eruption like
measles, cough and laborious breathing resembling an alarming stage of
croup, muttering, delirium, &c. He got an emetic of Ipecac, from an allo-
pathic physician, which seemed greatly to mitigate the symptoms, and when
I saw him the next day he was quite comfortable.
Case 11. Diarrhoea; reported by Dr. Bishop.
Mrs. C, a?t. 40. Gastralgia and bilious diarrhoea. Pain and tenderness
at the pit of the stomach, with burning sensation, as in some cases of
acidity; feecal discharges, yellowish, bordering on green, nearly painless.
This lady had occasionally been subject to long and severe affections of the
stomach, sometimes connected with obstinate constipation, at other times
diarrhoea. She attributed it to erysipelas, which at times made its appear-
ance upon the lower limbs and upon various portions of the body. I have
seen it occupying the lower limbs in the form of dark purplish and painful
tumefactions attended with much constitutional disturbance. I have treat-
ed her homoeopathically for what she called "Erysipelas in her stomach."
From these attacks she would, after a long time, recover, but the results of
medical treatment were not at all satisfactory to myself. At this time she
had been laboring under the usual precursory symptoms, which had often
ushered in a long and protracted disease of the stomach. For about two
weeks the symptoms, it is true, did not indicate per se anything of peculiar
interest or difficulty, except in connection with past experience and obser-
vation in her particular case. I left her three doses of apis 3, with direc-
tions to repeat once in twelve hours if no aggravation of symptoms occur-
red, but if any occurred to omit the medicine entirely. The first dose in-
198 Ajpis-mellifica.
creased the burning sensation in the stomach, also the diarrhoea. This
aggravation subsided in eight or ten hours, with great improvement in all
the symptoms.
She took the second dose, which brought up the burning pain in the
stomach, as did the third ; the aggravation soon subsided, and I never knew
a more perfect and speedy cure than was produced by the three doses of
apis in this case. Her erysipelatous affection has never made its appear-
ance since.
Case 12. Eruptions ; reported by Dr. Bishop.
Mr. J. M. Eruptions upon the inner portion of the thighs, also below
the knees, upon the hands, face, and back of the neck, but more upon the
central portions of the body, with the following characteristics : commenc-
ing with small pustular formations just under the cuticle, with burning,
smarting, stinging sensation ; in coming to maturity, deposition of dry,
scabby matter, laminated form, scaly, brownish and sometimes light straw
colored. Looseness of the bowels in the morning, thin, watery, yellowish;
some griping at times, but generally painless. The looseness of the
bowels had continued three or four weeks. Treatment for the last ten
days, rhus and other antipsoric remedies : no abatement of symptoms,
either of skin or bowels.
On further examination I found the burning, stinging sensation in the
eruption more severe than I had imagined, and was, in consequence, in-
duced to try the apis. I had no attenuation of the remedy with me, and
accordingly medicated a portion of sugar with the mother tincture, much
less than one drop, then rubbed with another portion and dissolved a s n a
part of this in a cup full of water. Dose, one tea-spoonful twice in twenty-
four hours. Cured immediately and effectually of both diarrhoea and erup-
tion ; no return for eighteen months.
Case 13. Erysipelas ; reported by Dr. Greene.
Erysipelas of the whole of one side of the face and nose ; swelling un-
der the eye resembling that produced from the sting of the honey-bee.
Apis 3, ten or twelve drops in a glass of water ; dose, a spoonful repeated
in one to three hours until better. Swelling subsided entirely, and the
aext morning the young lady returned to her school and has had nothing
of the kind since to my knowledge.
Case 14. Metastasis of Eruption ; reported by Dr. Bishop.
J. C R., set. 35. Saw him at the commencement of his illness : symp-
toms indicated the fever peculiar to the locality where he resided ; chills for
five or six days, not much febrile re-action ; after some days improved so
much as to be out and oversee his business in part ; did not visit him again
in a week, and when called again his wife thought I had been mistaken in
the nature of his complaint, and that he was laboring under inflammation
of the lungs. On examining the case again I found the following symp-
toms :
Chest.— Sensation of soreness, as if from a recent mechanical injury.
Sensation as if the chest had been jammed, beaten, or bruised, especially on
the left side. Full inspirations did not particularly increase these sensations.
Tendency to chilliness and increase of these symptoms every other day ;
pulse 65, soft and feeble ; cough harrassing, especially at night; shortness
of breath, respiration much disturbed by exercise; bowels natural ; appetite
ffood.
Apis-melliftca. 199
Mercurius relieved his cough, and with the aid of ars., the periodicity
was suspended for nearly two weeks. Some remains of the lame, sore,
bruised feeling about the chest, also feeling of prostration and shortness of
breath, partial return of chills and slight aggravation of the symptoms every
other day. In this state he continued about two weeks, doing some light
labor without any medical treatment, except a few doses of mere, which
he took for his cough.
I was called to see him again in the night of Nov. 10th. Found him with
symptoms (apparently) of inflammation of the pleura and diaphragm ; but
little cough, respiration extremely painful, pulse rather full and somewhat
accelerated. He got a single dose of aconite, followed by bry. 3., in drop
doses once in 3 hours : next day much improved. Bry. 6, once in 8 hours.
Pain and soreness much better for several days, but shortness of breath and
feeling of prostration continued. The former symptom soon returned, viz. :
the peculiar sensation in the left side of the chest, also under the short ribs
and in the mediastinal region, respiration not increasing the pain. I had
supposed the present symptoms to be connected in no small degree with
chronic rheumatism, but at this time my attention was called to what he
denominated salt rheum, which had for many years ■ troubled him more or
less. Its retrocession from the surface had always been attended with
what he termed rheumatic pains ; but when the eruption was upon the
surface he was free from them. I then recollected giving him ars. some 5
or 6 years before, for the eruption upon the hands, with much benefit, as he
assured me it had never made its appearance since on his hands, but some-
times upon his body, especially about the chest. There had been nothing
of it upon any portion of the surface for some time previous to his present
illness. I made a pretty thorough trial of ars. and other remedies, but
without any partieular benefit ; and at length he made up his mind to either
go South and spend the winter, or try hydropathic treatment. On a careful
re-examination of the chest symptoms, 1 found they corresponded with the
pathogenesis of Apis-mel., according to my own provings of that remedy,
more perfectly than I was aware of, and in the following particulars :
sensation in the muscles of the chest as of having been bruised, jammed, or
beaten, pain in the left side under the short ribs, shortness of breath, espe-
cially on exercise, disposition to chilliness and a peculiar prostration of the
great central organic nervous power, or that anomalous condition of the
vital forces of the nervous centres, which, in its details, is often so perplex-
ing to the practitioner, especially if pressed by the patient to give his disease
a name. This consideration, as well as the clinical test of the remedy, in
some cases of psoric disease induced me to try apis 3, in doses of a quarter of
a drop. The first dose was attended with the disturbance in the region of
the diaphragm and stomach already described, followed by the looseness or
painless diarrhoea to which I have already alluded in the proving of apis. I
saw him the next day after my prescription, and he assured me this was
emphatically the remedy : that he felt every way better than he had done
for some weeks; that he began to feel strong and like himself; was not
troubled with shortness of breath, or any sore feeling or pain about his
chest. He took the remedy once in a day or two for a time, and has
remained perfectly sound and healthy ever since.
Case 15. Gastro-enteritis ; reported by Dr. Bishop.
M. T., jet. 8 years. Gastro-enteritis, ushered in by vomiting, extreme
pain and tenderness in the region of the stomach and upper portion of the
abdomen, fetid breath, foul tongue, constipation, disturbed sleep at night,
200 Apis-mellifica.
muttering, &c, much disturbed from dreams, pulse frequent, wiry. After
one week's treatment, during which time there was not much abatement of
the vomiting, or even of any of the prominent symptoms, I gave apis 3,
three doses; next day found him better, rested quite well during the night,
tenderness and pain much less; and from this time, the prominent and
troublesome symptoms abated, passing off entirely in a week.
Case 16. Incipient Hydrocephalus ; reported by Dr. Bishop.
Miss F., get. 8 years. Dull, stupid state during the day, much inclined to
sleep. At night, during sleep, talking, dreamy state; sleep in the morning
profound — cannot be waked without being taken out of bed, shaken and
forced about for a time. Great languor and lassitude, pale face, slight
constipation, urine small in quantity — has been ill about two weeks. The
mother informed me that, eight years before, a daughter of the same age
sickened in precisely the same manner, and, at length, died of dropsy of the
brain. I prescribed various remedies for ten days without any apparent
benefit to the patient. The child inherited from her mother a psoric taint,
which, in the parent, generally manifested itself in the form of urticaria,
and sometimes on the lower extremities in detached and isolated elevations,
painful and tender to the touch, and always assuming in their progress a
purplish or livid hue. A few such spots were faintly visible upon the neck
and forehead of the child, not having attained any elevation above the
surface, or hardness.
I left her three doses of apis 2. She got one dose at 11 a.m., one at 3,
and the other at 7 p.m. Her sleep, for the first time since her illness com-
menced, was comparatively quiet that night; awoke early the next morning,
was lively and somewhat disposed to play and amuse herself about the
house — had much more color in her face than at any time for two weeks.
She began to improve visibly soon after taking the second dose. Next day
left three more powders of the third — had more disturbance that night in
her sleep than in the preceding one, but awoke early in the morning, and
was out to play in the afternoon. Hard purplish spots upon the face, fore-
head and neck, and lower limbs, made their appearance in the second and
third days after taking the medicine. These remained hard and painful
some ten or twelve days, and disappeared. She was some time in regaining
her strength and bodily activity, but at length became entirely well.
Case 17. Hydrothorax ; reported by Dr. Wells.
Mrs. J. H. C, a?t. 58, has been troubled with anasarca several years, and
more recently, has had decided symptoms of hydrothorax, as sensation of
fulness in the chest, shortness of breath, pains, sometimes dull and some-
times sharp, in the chest, inability to lie in the horizontal posture. Dec.
10th, 1850, commenced taking apis 3, every two days for two or three
weeks, and then at longer intervals, with complete relief to all of the symp-
toms. Saw her in June, 1851, quite well.
Case 18. Inflammation of the labia; reported by Dr. Humphreys.
A lady of 38, mother of several children, had an extremely large and
painful swelling of the labia, attended with violent heat and stinging pains.
She received apis 30, a spoonful every three -hours in the afternoon and
before the next morning the swelling and pain had disappeared and she was
rapidly restored.
Api&-mellifica. 201
Case 19. Ophthalmia; reported by Dr. Humphreys.
A young lady, set. 18, fair complexion, rather lymphatic temperament, was
attacked in Oct., 1850, with a violent inflammation of the right eye. It came
on suddenly without apparent cause, and she went into the hands of a
skilful allopathic practitioner, who treated her five months, when my advice
was sought. During his treatment three ulcers had formed on the cornea,
one in December and two others in February. She had taken considerable
medicine internally, frequent blisters behind the ears and had used various
washes, &c. When I was called in, the ulcers, which had been nearly
healed, were worse, the vessels of the eye injected, dreadful pain darting
through the eyes, intolerance of light in both eyes, keeping them constantly
closed ; the entire cornea was scattered over with dark, smoky clouds, and
thickened and covered with a film.
She could only discern the light of a window when turned towards it,
and the pupil could not be discovered through the smoky and discolored
cornea. The albuginea was dark red, the redness running insensibly into
the cornea, tears of scalding water ran from the eye ; cold feet, hot head,
delaying menses. I commenced treatment in February. She received
merc.-cor. and bell, mere, and hep. 3, until March 20th, at which time the
temperature of the surface had become normal, the intolerance of light less,
yet the general appearance of the eye and sight indicated no very marked
improvement.
March 20th. She took apis 30 in water, a spoonful morning and evening.
The effect was immediate. The following morning the eye looked clearer
and she remarked that she could even see the eyes of her sister. From
thence the improvement was rapid and permanent, and on the first of May
she was discharged. There remained only a slight opacity of the cornea,
which has since entirely disappeared. I have never witnessed so rapid,
perfect and brilliant a cure in my experience. She took no other medicine,
with the apis 30, except an occasional dose of aeon., when the pain in the.
extremities and heat became too violent.
Case 20. Ophthalmia ; reported by Dr. Humphreys.
A woman of 50, dark complexion, bilious temperament, had suffered from
ophthalmia for three years, and had been, with little benefit, under the care
of several oculists. Her eyelids were swelled, dark red, everted, denuded
of the lashes, granulations along the edges, the conjunctiva reddened and
full of dark vessels, the cornea darkened and smoky, vision very indistinct,
eyes intolerant of light, running and agglutinated. Apis 30, every three or
four days, changed the entire aspect of the case. The eyelids were relieved
entirely, the conjunctiva lost its dark vessels, the cornea became clear, vision
improved, and she left almost entirely well.
Case 21. Tonsillitis ; reported by Dr. Humphreys.
A lady, set. 26, subject to frequent attacks of quinsy, which, despite the
application of the usual remedies, bell., lack, and mere, generally ended in
suppuration, was taken with one of the old attacks, viz., chilliness, then
heat, violent pain in the temples, redness and swelling of the tonsils, uvula
and fauces, painful difficulty of swallowing, stinging pains in attempting to
do so. She received first aconite, then apis 30, which soon afforded relief,
and under its use in 24 hours every vestige of the complaint disappeared.
She declares that she has never received such marked and substantial relief
from any other medicine as from it.
202 Apls-mellifica.
Case 22. Tonsillitis ; reported by Dr. Humphreys.
An unmarried lady, set. 28, frequently subject to sore throat, was attacked
with one of her usual ill turns, viz., violent pain in the forehead, lachrymal
disposition, discouraged, desponding mood, very greatly enlarged tonsils
with redness and swelling of the uvula and entire fauces, also great difficulty
of deglutition, and smarting pain in the throat; no appetite, tongue coated.
Aeon, and bell, were given for twenty-four hours with no particular relief,
when I resorted to apis at intervals of four hours either alone or in alter-
nation with mere. An immediate and decided effect was produced, and in
twenty-four hours she was dismissed with only a few doses of apis in case
of relapse.
Case 23. Reported by Dr. Wells.
Mr. N. B. has had pains in the left hypochondriac region, extending
upward into the chest. This case of several years' duration, had not been
benefitted by the usual remedies, arnica, sulph., &c. Took a few doses of
apis 3, which entirely removed the disease.
The following cases by Mad. De Bonneville were communicated to
Dr. Humphreys by Dr. Hering. The guide in the choice of the remedy-
was the symptom of swelling.
Case 24. — An old woman, some 80 years of age, sanguine nervous bilious
temperament, had a white puffy swelling of a paralyzed arm and hand.
Three doses of the apis, one given daily, produced an entire removal of this
symptom. About three months afterwards the same person from excessive
grief became paralyzed upon her entire right side. Some ten days after
her second stroke, the same symptom, swelling, occurred over the entire
side, entirely closing her right eye. A few doses of the apis entirely
removed this symptom.
Case 25. — A woman about 37 years of age, sanguine nervous tempera-
ment, had both her eyes closed with a purplish, white swelling, preceded
by intense pain in the right eye. One dose of the apis removed the swelling
and when it returned a fortnight or so afterwards it was again removed by
one dose, and has not returned again in eleven months.
Case 26. — A girl of 13 years. Gave the apis for a dark, puffy swelling
under the eyes ; a dose every three days for about a fortnight, with success.
Case 27. — A child of nervous temperament, fifteen months old, had a
whitish, red swelling of the lower portion of the anus, attended with into-
lerable itching. Two doses of the apis at an interval of six days, entirely
removed the affection.
Case 28. — A man of 28. years; sanguine nervous bilious temperament. —
Sudden paralysis of the entire right side, with violent delirium, at times
amounting to phrensy. Gave the apis the first medicine, as I learned from
his wife that he had, before his attack, sudden whitish swellings that itched
violently upon his head, and sometimes upon his neck. In less than an
hour after giving the apis he was broken out in countless places upon his
head, and much quieted in his mind. The swellings subsided before morning,
and his phrensy was such as to require three men to hold him from throw-
ing himself headlong from the bed.— Gave hep.-sul. one dose and the apis
fifteen minutes afterwards ; and he become rational for the most part of the
day, and much broken out upon the calves of his legs. Used the apis
several times afterwards in this case, always with marked success.
Case 29. — Used it for a lad fifteen years of age, lymphatic sanguine
Aristolochia-milJiomens. 203
temperament, who had been poisoned in the woods, upon the face and
hands without benefit. Used rhus-rad. with complete success.
Case 30. — A woman of about 30 years. Sanguine nervous temperament.
Swelling of the tongue, with a dry, glossy, yellowish appearance, accom-
panied with excessively painful vomitings of bile, &c. Gave mix and bryonia
until the vomiting was subdued, the swelling of the tongue continuing, gave
apis twice, once in three hours, with a decidedly good effect. A few
months afterwards for the same symptoms gave the same medicine with
good results.
Case 31. — A young man about 20 years old, of sanguine bilious lym-
phatic temperament, had been thrown from a horse and his left knee badly
sprained. Gave the apis for the swelling, one dose. Some two weeks
afterwards from standing upon it too much, the knee again swelled, and the
use of the apis, one dose, immediately removed the swelling.
Case 32. — A woman of about 30 years had swelled eyes every morning
for a long time. Cured by three doses alternated with sulphur. I never
saw her.
Case 33. — A man of about 45 years, nervous sanguine temperament. —
Painful, puffy swellings of the knees. Five doses alternated with iodium,
a dose once in three days, cured the affection.
7.— ARISTOLOCHIA MILHOMENS.
ARIST.-MIL. A. Grandiflora (Gom.). A. Cymbifera (Mart.).
Snakeroot.
1. Description and Preparation.
Very many species of Aristolochia have been used in medicine in
different countries. Among these the A. serpentaria, a very common
plant in the United States, has become so popular that the root (the
part employed medicinally) is sold by the bale, and forms an extensive
article of traffic. The species used by Mure in the following provings
is an inhabitant of Brazil, and is thus described by him (Pathogenesie
Bresilienne, 315) :
" A climbing plant ; stem glabrous ; leaves alternate, uniformly cor-
date, ribbed, presenting between the ribs reticulated veins ; petioles
long, furnished with a large, entire, uniform, sheathing stipule ; flowers
solitary upon a sulcate peduncle, eight or ten centimetres long; peri-
anth single, very large, of a yellowish brown, tuberculated, curved, di-
vided into two lips ; the upper acute and lanceolate, bent a little out-
wards ; the lower twice as long as the other, dilated at the base, and
204 Aristolochiarmilhornens.
4
expanding into a large oval disk with waved edges. The whole flower
is covered with prominent nerves. Stamens six, epigynous ; ovary
o-labrous, surmounted by a stigma with six very short and rounded
lobes."
The part employed in the following provings was the flower.
2. Prior Knowledge of its Effects.
We are not aware of any experiments with the particular species
employed by Mure. The A. pistolochia, longa, clematitis and ser-
pentaria have been long employed in medicine both in Europe and in
this country. They are considered, in the undistinguishing jargon of
the old school, to be " stimulant tonics, acting also as diaphoretics or
diuretics, according to the mode of application. The A. Serpentaria
too largely taken occasions nausea, griping pains in the bowels, some-
times vomiting and dysenteric tenesmus * * . It has been highly
recommended in intermittent fevers, and though itself generally inade-
quate to cure the complaint (!), often proves serviceable as an adjunct
to Peruvian Bark or the Sulphate of Quina. It is sometimes given in
dyspepsia, and is employed as a gargle in malignant sore throat."
(Wood and Bache Dispensatory, 660.)
It is not worth while to accumulate matter of this sort, especially as
both the species and part of the plant used in the provings were
different.
3. Provings.
There was but one prover ; his name is not given, nor is he des-
cribed, nor are the doses taken particularly stated. The experiments
of the Brazilian School were generally made with the fourth or fifth
dilution.
1st day. Disturbed rest. He dreams that he can neither eat, nor
drink, nor walk. Throbbing in the right frontal eminence for a minute.
Mouth pasty through the whole morning. Thirst. Pain in the right
groin. Swelling of the left leg. Swelling of the lower part of the
calf. Borborygmi in the stomach and intestines. Lancinations through
the whole extent of the left inferior extremity. The left leg is red and
inflamed. Head heavy. Great thirst, with bitterness of the mouth.
Anorexia. Stinging in the hypothenar eminence of the left hand ;
half-past 3 r. m. Sensation of torpor at the vertex. Pricking in the
right testicle. Pricking in the right thigh. Prick as from a pin in
the lower part of the left leg. Itching on the internal surface of the
left thigh. Prickings in different parts of the body. Pain in the
hypothenar eminence of the right hand at 1 p. m. Sensation of tor-
por in the cerebellum. Prick under the heel. Itching on the external
malleolus of the left foot ; 8 p.m. Itching on the skin of the
prepuce. Cramp-like pain in the right internal malleolus. Bruised
pain over the left pectoral muscle, which is sensitive to the touch at
night.
Aristolochia-milhomens. 205
2c? day. Unquiet sleep. He dreams of a sheep and a dog cov-
ered with red scarves ; the first, elevated above the ground, shook his
head, and was seized by the dog in the middle of his back ; the dog
himself was suspended by the back by a man accompanied by many other
individuals. Afterwards a very amorous dream, with pollution. Pain-
ful spot under the scapula, as if from having received a blow. Disa-
greeable sensation behind the left internal malleolus. Uneasiness, then
pricking in the thighs at 2 p. m. Bruised pain in the left knee.
Lancinations in the anterior part of the left external malleolus, at 7
p. m. Fulness of the stomach. Acute pain in the right thigh. The
leg is swollen and violet-colored in the morning; it becomes inflamed
by fatigue, and turns a blackish red towards evening. Want of appe-
tite. The whole leg is covered by large irregular patches, formed by
extravasated blood. He makes water more frequently than usual. The
head is burning hot. Continual thirst and bitter mouth. Excoriations
of the lips and gums. Complete anorexia. The left leg is painful, as
if excoriated ; the pain passes to the right internal malleolus, and be-
comes more acute.
3c? day. Lancinating pain at the apex of the heart, which takes
away his breath at night. His temples are very sensitive to touch
during the whole day. Stiffness of the leg, with impossibility of stand-
ing up for a few minutes. Sharp pain between the shoulders. Dull
pain at the lower part of the lumbar region, and in the hypogastrium.
Burning pains at the anus. Excoriations of the lips and gums as yester-
day. Itching above the bend of the right arm. Cramp-like pain in the left
tendo Achillis. Partial swelling around the malleoli. Bruised pain
under the left patella at 3 p. m. Lancinations in the lower part of the
right leg and internal malleolus at 3^- p.m. The upper and lower
parts of the left arm are painful to the touch at 4| p. m. Painful
lancinations in the internal part of the left knee. Pricking in the joint
of the first phalanx of the little finger at 8 p. m.
\ih day. Pain in the. dorsal portion of the left index. Colic, fol-
lowed by a stool first soft, then diarrhceic twice in succession, in the
morning. Malaise, as if something were collected in the internal part
of the right leg above the knee, during the evening and part of the
night.
5 th d.ay. Uneasiness in the lumbar region. Feeling as if the
lower part of the right leg had a tendency to fall down upon the mal-
leoli, as a stocking might do ; he often carries his hand there, as if to
raise it up. Itching on the anterior part of the right leg. Pricking
on the internal surface of the right leg. Uneasiness in the lower part
of the tendo Achillis. Easy stool.
6th day. Itching on the internal malleolus of the left foot. Itch-
ing on the right thigh. Pain above the right internal malleolus. Dis-
gusting dreams.
1th day. Malaise after waking in the morning; he cannot go to
sleep again; he feels as if something incommoded him about the mal-
leoli for several hours. This pain increases, becoming a bruised pain
206 Aristolochia-millwiiuits.
towards 3 p.m. The malleoli appear swollen. Acute pain in the
sacro-lumbar region. Pain in the right side.
8th day. Pain at the scrobiculus. The pains in the legs continue.
Persistent pain above the left internal malleolus. Smarting on the in-
terior, superior part of the right thigh in the evening. Acute lancina-
tion in the head in the evening.
9 th day. Acute lancination in the left side of the head in the evening.
10th day. Severe lancination behind the head. The upper part
of the left leg is painful to the touch. Shootings in the cerebellum.
4. Digest of the Symptoms.
AUTHORITY. Pathogenesie Bresilienne, 315.
The figures refer to the da}' on which the symptom was observed.
HEAD. Head heavy (1). The head is burning hot (2). Throbbing
in the right frontal eminence for a minute (1). Sensation of torpor at the
vertex (1). 5. His temples are very sensitive to touch during the
whole day (3). Acute lancination in the head (evening, 8). Acute
lancination in the left side of the head (evening, 9). Severe lancina-
tion behind the head (10). Shootings in the cerebellum (10). 10.
Sensation of torpor in the cerebellum (1).
MOUTH. Mouth pasty through the whole morning (1). Excoria-
tions of the lips and gums (2). Excoriations of the lips and gums as
on the second day (3).
APPETITE. Anorexia (1). 15. Want of appetite (2). Com-
plete anorexia (2). Thirst (1). Great thirst with bitterness of the
mouth (1). Continual thirst and bitter mouth (2).
STOMACH. 20. Borborygmus in the stomach and intestines (1).
Fulness of the stomach (2). Pain at the scrobiculus (8).
_ STOOL AND ANUS. Colic, followed by a stool, at first soft, then
diarrhoeic, twice in succession (morning, 4). Easy stool (5). 25.
Burning pains at the anus (3).
URINARY AND GENITAL. He makes water more frequently
than usual (2). Itching on the skin of the prepuce (1). Pricking in
the right testicle (1).
CHEST. Lancinating pain at the apex of the heart which takes
away his breath at night (3). 30. Bruised pain over the left pectoral
muscle, which is sensitive to the touch at night (1).
BACK. Painful spot under the scapula, as if from having received
a blow (2). Sharp pain between the shoulders (3). Pain in the right
side (7). Uneasiness in the lumbar region (5). 35. Dull pain at the
lower part of the lumbar region and in the hypogastrium (2). Acute
pain in the sacro-lumbar region (7).
SUPERIOR EXTREMITIES. The upper and lower parts of the
left'arm are painful to the touch (4|- p.m. 3). Itching above the bend
of the right arm (3). Stinging in the hypothenar eminence of the left
Aristolochia-millwmens. 207
hand (3^ p.m. 1). 40. Pain in the hypothenar eminence of the right
hand (7 p.m. 1). Pain in the dorsal portion of the left index (4).
Pricking in the joint of the first phalanx of the little finger (8 p.m. 3).
INFERIOR EXTREMITIES. Pain in the right groin (1). Lan-
cinations through the whole extent of the left inferior extremity (l).
45. The left leg is red and inflamed (1). Swelling of the left leg (1).
The leg is swollen and violet-colored in the morning ; it becomes
inflamed by fatigue and turns blackish red towards evening (2). The
whole leg is covered by large irregular patches formed by extravasated
blood (2). Malaise as if something were collected in the internal part
of the right leg above the knee (evening and part of night, 4). 50. The.
pains in the legs continue (8). Uneasiness, then pricking in the thighs
(2 p.m. 2). Stiffness of the leg, with impossibility of standing up for a
few minutes (3). Pricking on the internal surface of the right leg (5V
Smarting on the internal superior part of the right thigh (evening 8).
55. Pricking in the right thigh (l). Acute pain in the right thigh (2).
Itching on the right thigh (6). Itching on the internal surface of the
left thigh (l). The upper part of the left leg is painful to the touch
(10). 60. Itching on the anterior part of the right leg (5). Bruised
pain in the left knee. Bruised pain under the left patella (3 p.m. 3).
Painful lancinations in the internal part of the left knee (3). Prick as
from a pin in the lower part of the left leg (l). 65. Swelling of the
lower part of the calf (1). Cramplike pains in the left tendo Achillis
(3). Uneasiness in the lower part of the tendo Achillis (o). Prick
under the heel (1). Malaise after waking in the morning; he cannot
go to sleep again ; he feels as if something incommoded him about the
malleoli for several hours (7). This pain increases, becoming a bruised
pain (towards 3 p.m. 7). 70. Partial swellings around the malleoli (3).
The malleoli appear swollen (7). Feeling as if the lower part of the
right leg had a tendency to fall down upon the malleoli as a stocking
might do ; he often carries his hand there as if to raise it up (5).
Cramplike pain in the right internal malleolus (1). Pain above the right
internal malleolus (6). 75. Lancinations in the lower part of the right
leg and internal malleolus (3£ p.m. 3). The left leg is painful as if
excoriated ; the pain passes to the right internal malleolus and becomes
•more acute (2). Lancinations in the anterior part of the left external
malleolus (7 p.m 2). Itching on the left external malleolus (8 p.m l).
Itching on the left internal malleolus (6) 80. Persistent pain above
the left internal malleolus (8). Disagreeable sensation behind the left
internal malleolus (2).
SLEEP. Disturbed rest (l). Unquiet sleep (2). Dreams. Dis-
gusting dreams (6). 85. He dreams that he can neither act nor drink
nor walk (1) He dreams of a sheep and a dog, covered with red
scarves; the former, elevated above the ground, shook his head and was
seized by the dog in the middle of his back; the dog himself was
suspended by tlie back by a man accompanied by many other indivi-
duals (2). Afterwards, a very amorous dream with pollution (2).
GENERAL. Prickings in different paits of the. body (I). ..
P
208 Arsenicum-metallicum.
8.— ARSENICUM-METALLICUM.
ARS-MET. Metallic arsenic.
1. History, Description and Preparation.
The various preparations of arsenic have long been known. Aris-
totle, Dioscorides and Theophrastus are said to have been acquainted
with the compound which it forms with sulphur, called auri-pigmentum
or orpiment. It is most frequently found in composition, but some-
times in the metallic state. It was first carefully examined by Brandt
in 1*733, and has since been very thoroughly investigated by succeed-
ing chemists.
Arsenic is a brittle metal of a bright steel-gray color, and a density
of about 51. Its attraction for oxygen is considerable, as when exposed
to the air it soon tarnishes ; it is said to be perfectly preserved under
water. At 356° Fahr. it volatilizes without fusing, and may be obtained
by condensing the vapor, which has a strong smell of garlic, in crys-
talline scales. It is isomorphous with phosphorus, tellurium and anti-
mony, and seems to have relations of a similar kind with nitrogen.
The metal may be obtained in a state of purity by heating in a glass
retort a mixture of one part of white arsenic and three parts of black
flux ; it condenses, in the neck of the retort, into a metallic crust.
2. Prior Knowledge of its Effects.
This may be summed up in the words of Christison : " In confor-
mity with what appears to be a general law in toxicology, the metal
ITSELF IB INERT."
3. Provings of Metallic Arsenic*
FIRST PROVING.
Dec. 24, 1850. For three successive evenings one grain of the third
trituration was taken.
*The metal used in the following provings was prepared in perfect purity at the
laboratory of Professor Lehmann, in Leipzig, in 1&45, by Dr. Buchheim, now
professor of Materia Medica, in Dorpat. It had not altered, and had its full metal-
lic lustre when in 1847 triturations were made in dry weather by Rademacherj
Arsenioum-metallicvm. 209
Dee. 25. First day. Slept unusually well last night, cannot keep
awake in the evening. Ulcer on the right inner side of the underlip sore,
when the tongue touches it. Gums swollen and painful to the touch.
Dec. 26. Second day. On awaking in the morning, sensation as
if the head was swollen. The normal pulse being 55, is accelerated
to 68 in the morning, with pulsations all over the body. Sensation of
lameness in the right hip-joint, as if he could not use the right limb,
but can walk well enough after using it. Pulsation all over, especially
in the right hip-joint, worse in the morning, better in the evening.
Dec. 27. Third day. Has slept better and longer than usual, is
very reluctant to rise in the morning. The same ulcer on the inside of
the lip as on the first day, only on the left side.
SECOND PROVING.
Jan. 3, 1851. Same prover. Every evening for three days one
grain of the first trituration.
Jan. 4. First day. At nine o'clock a. m., pulsation all over the
body, especially under the sternum, pulse (the normal pulse being 55)
is 68, heavy and dull feeling in the forehead, eyelids slightly inflamed
and swollen. Dry heat in the palms of the hands. Dry mouth ;
tongue coated with whitish mucus. Bloated feeling and burning in
the feet. Lumbago.
Jan. 5. Second day. Pulse 68 in the morning, 53 in the evening.
In the afternoon tension and sensation of swelling in the abdomen,
with feeling of heaviness of head, like vertigo.
Jan. 6. Third day. Last night, sensation of swelling of hands,
fingers and feet, feels as if he could not close the hands, cracking of all
the finger-joints. Slept little, with great inclination to sleep. Sensa-
tion of swelling of the head, face feels as if bloated. Pain in the left
side of the head, extending to the left eye and left ear, with nausea.
Pulse in the morning 68. Hot eructations as of bile. Headache,
worse when laughing. Soreness of the scalp when pulling even but
one hair; bloated abdomen. Debility and general sensation of pros-
tration.
Jan. 7. Fourth day. Restless sleep, with sensation of fulness of
the head, felt while sleeping, and worse when awaking. At night
burning of hands and feet ; eyes so painful that he cannot read much.
In the morning pulse 68, in the evening 43. Dreams of danger, prin-
cipally danger of water.
Jan. 8. Fifth day. Pulse 72 in the morning, 64 in the evening*.
Feels pulsations ah over. Slept better last night, but still restless.
with his usual exactness. A new mortar was Hsed and kept for further triturations
in the same manner as I have done with all other chemicals.
All the following provings were made under the direction of Dr. Lippe ; and
most of the symptoms were taken from a thesis of Doctor Stevenson, a graduate
of the Pennsylvania Homoeopathic College, in 1851, with his permission.
C, Heking,
210 Arsenicum-meta llicum.
Feels all the time while sleeping as if he would have headache in the
morning on awaking.
Jan. 15. Twelfth day. Varices on the right side of the anus;
painful after stool, but not bleeding.
THIRD PROVING.
Jan. 16, 1851. Same pr over. For five successive evenings every
evening six pellets of the 30th potence of Ars.-met.
Jan. 17. First day. At this morning pulse 49, at 9 a.m.,
pulse 64, full and strong with throbbing sensation all over the whole
body. Piles still external, but better. At 10 p.m., pulse 48. Burn-
ing sensation in the feet.
Jan. 18. Second day. Feet burning hot last night without any
moisture ; he was compelled to hold the feet out of bed all night.
At 6 a.m., pulse 48. At 9 a m., pulse 68, with throbbing sensa-
tion all over ; feeling of drowsiness also ; he slept well last night; feel-
ing of despondency and lowness of spirits, which is found difficult to
shake off; gums swollen, feel as if scalded, with accumulation of
water in the mouth ; slight pains in the left side of the chest near the
heart; piles still external on the right side of the anus.
Jan. 19. Third day. Slept well last night; feet did not burn so
much; in the morning tongue is coated white; the imprints of the
teeth are seen on the edges of the tongue. Pulse, 9 a.m , 68, full and
hard. Piles have nearly disappeared ; gums not so much swollen and
feel not as scalded as yesterday ; red sandy deposit in the urine; throb-
biny sensation like that of yesterday.
June 20. Fourth day. Pulse in the morning 64 ; itching and
burning in the lower part of the face; piles bleed a little.
June 21. Fif.h day. Pain in the muscles of the left chest;
great lassitude; throbbing all over. Coryza; scalding water runs
from the nose, excoriating the nostrils ; great lassitude and prostration
of strength ; a burning itching in the lower part of the face as if an
eruption would come out.
June 22 — 21. Sixth till eleventh day. Itching, burning, stinging
in the face, with swelling; worse at night. Relieved by washing the
face in cold water. On the right forehead and in the right groin it is
worst. Forehead feels much swollen ; the skin is stiff drawn over
the forehead, immovable The itching i> relieved by pressing (and
flinching), not by scratching. For many nights past very unpleasant
dreams, full of danger by water, he is in imminent danger of being
drosvned,_&c.
Later. Desijua'i ations of skin in very small scales. A scab which
he had had for twenty years on the first joint of the third finger of the
left hand healed entirely; when formerly the scab had been torn off, a
liver colored spot remained, on which a new scab formed.
Feb. 8. No more medicine had been taken, but the same coryza as
before returned again, accompanied with hoarseness, and on the 9lh with
Arsenicum-metallicum. 211
very intense inflammation of the throat for which one dose of bella-
donna, 400, was successfully administered.
FOURTH PROVING.
Dec 11, 1850. Another prover. For six. successive nights one
dose of one grain of the third trituration was taken.
^ Dec. 12. First day. Feels as if the fumes of whiskey had gone to
his head ; great drowsiness in the afternoon, and irresistible sleepiness
early in the evening.
Dec. 13. Second day. From 11 a. m., till evening, irresistible
sleepiness; feels as if he should fall asleep while walking in the street
in the afternoon. The following five days great lassitude, weakness,
and depression of spirits.
FIFTH PROVING.
Jan. 16, 1851. Same prover. Took for six days, every evening,
six pellets of the 30th potence of ars.-met.
Jan. 17. Pulsations in the umbilicus and right anterior tibial artery
at the superior extremity of its inferior third. Deep-seated numbness
in the region of the right hip-joint, extending to the pubes.
Jan. 18 — 26. The feet, usually icy cold, have become warm and
sweat more. Numbness in the right lumbar region and inside of the
right thigh down to the knee, extending from the vertebrae down to the
crest of the ilium.
Jan. 27. (Edematous swelling of the forehead and face, with itching
which can only be allayed by pinching the skin. Itching in the right
groin down to the knee.
SIXTH PROVING.
Feb. 7. Same prover. One dose of six pellets of ars.-met., 30.
Feb. 9. Awakes in the morning at six o'clock with a distressing,
lancinating, griping pain in the bowels; afterwards one sharp, burning,
watery stool, relieving the abdominal pains, but leaving great weakness;
he falls asleep after sitting down ; pulse 60, full.
Later. Sensation of dryness in the right knee-joint. In the right
groin a painful, swelling pain goes up to the hip and is worse when the
leg is extended ; worse when sitting, the leg then goes to sleep; better
when walking. This pain continued for a long time in the same place.
Where this painful swelling is felt a bubo suppurated 24 years ago.
4. Digest of the Symptoms.
The figures indicate the attenuation by which the symptoms were produced.
MENTAL. 1. Depression of spirits. Despondency. Indifference.
HEAD. A sensation as of vertigo (2d d.) (1). 5# Sensation as if
212 Arsenicum-metallicum.
the fumes of whiskey had gone to the head (1st d.) (3). Heavy and
dull feeling in tho forehead (1st d.) (1). Pain in the left side of the
head extending to the left ear and left eye, with nausea (3d d.^ (l).
Head feels as if swollen in the morning when awaking (2d d.) (3).
Sensation of fulness in the head while sleeping, and worse when awaking
in the night (4th d.) (l). 10. Headache worse when laughing.
Itching of forehead which cannot be allayed but by pinching up the
skin (12th d.) (30). Soreness of the scalp when even pulling but one
hair (3d d.) (l).
EYES. Sensations of heaviness in the eyes. Eyelids slightly
inflamed and swollen (1st d.) (1). 15. Eyes so painful that he cannot
read much.
NOSE. Fluent coryza. Vide 52. Scalding water runs from the
nose, excoriating the nostrils (5th d.) (30). The coryza returns in fifteen
days with heat in the face and hoarseness, lasting three days, when it
became accompanied with angina faucium, for which bell. 400, one
dose, was successfully administered.
FACE. Itching and burning in the lower part of the face, as if an
eruption would break out (4th d.) (30). 20. Face feels as if bloated
(3d d.) (1). Bloated face (3d d.) (1). Itching all over the face, which
can only be relieved by pinching the skin (for some days). Burning,
itching, stinging in the face, with swelling ; skin feels as if stiff, relieved
by bathing the face with cold water ; later, desquamations in small
scales. The itching is relieved by pressing, but not by scratching.
MOUTH. 25. Ulcer on the right side of inner under lip (1st d.)
(3). Ulcer sore when touched with the tongue (l-2d d.) (3). Ulcer
on the left inner side of the under lip (1st d.) (3). Dry mouth.
Tongue coated white, covered with mucus (12th d.) (1). Tongue
coated white, showing the imprint of the teeth on the edges (3d d.)
(30). 30. Gums swollen and painful to the touch (1st d.) (l). Gums
swollen and feeling as if scalded, with accumulation of water in the
mouth ; aversion to wines and liquors.
STOMACH. Nausea (3d d.) (1). Hot eructations as of bile (3d
d.) (1).
ABDOMEN. 35. Bloated abdomen (l-3d d.) (1). Tension and
sensation of swelling in the abdomen (3d d.) (1). Pulsation in the
umbilicus. Numbness and sensation of paralysis in the right lumbar
region, extending from the vertebras to the crest of the ilium (1st d.)
(30). Lumbago. 40. Varices on the right side of the anus, painful
after stool (not bleeding) (12th d.) (l). Varices bleed a little (4th d.)
{30.) Varices feel only sore, but neither pain after stool nor bleed
(16th d.) (30.) After awaking in the morning at 6 o'clock, distressing,
lancinating, griping pain in the bowels ; afterwards, one sharp, burning,
watery stool, relieving the abdominal pain, but leaving much debility ;
he falls asleep sitting on a chair, and has no appetite; pulse 60, much
fuller than in health (2d d.) (1). 45. Constipated (16th d.) (30).
GROINS, URINE. Itching in the right groin extending down to
the knee (12th d.) (30). In the right groin a painful swelling, worse
Arsenicum-metallicum. 21 #
when extending the leg, pain goes up to the hip and continues for a
long time. In the same place where this painful swelling appears, a
bubo suppurated 24 years ago. Red sandy sediment in the urine (3d
d.) (30). Offensive sweat on the genitals (for some weeks).
CHEST. Pulsation under the sternum (1st d.) (30). 50t Slight
pains in the left side of the chest in the region of the heart (2d d.) (30).
Pain in the muscles of the left chest (2d d.) (30.) Hoarseness with
coryza (21st d.) (30). Vide 17.
UPPER EXTREMITIES. Sensation of swelling of hands and
fingers (3d d.) (1). Hands and fingers feel stiff; they feel as if they
could not be closed (3-9th d.) (1). Cracking of all the finger-joints
(2d-14th d.) (1). 55. Dry heat in the palms of the hands. *A scab
which had been on the first joint of the third finger of the left hand for
20 years, healed entirely ; when formerly the scab had been torn off, it
left a spot of liver color, and a new scab soon formed.
LOWER EXTREMITIES. Sensation of lameness in the right hip-
joint (2d d.) (3). Sensation as if he could not use the limb, but he can
walk well enough after he has been on his feet a short time (2d d.) (3).
Pulsation in the right hip joint, worse in the morning, better in the
evening (2d d.) (3). 60. Deep-seated numbness in the right hip-joint
(1st d.) (30). Sensation of paralysis in the right hip-joint, extending to
the pubic symphysis down inside of the thigh to the knee. Pulsation
in the right anterior tibial artery at the superior extremity of its inferior
third (1st d., 1 and 1st d.) (30). Sensation of dryness in the right
knee-joint (4th d.) (3). Feet burning hot, feel as if bloated (1st d.) (1).
65. Feet burning hot, without the least moisture (2d d.) (30). *Feet
usually icy cold, have become warm and sweat much. Feet burning
more at night ; he has to hold them out of bed, cannot have the least
cover on them (1-1 4th d.) (l and 3).
GENERAL. 70. Emaciation. Pulsation all over the body. The
symptoms appear first on the right and then on the left side. Morning
exacerbations. The symptoms recur again after two weeks. Aggra-
vation after drinking a small quantity of brandy, for which he had not
the slightest desire.
SLEEP. 75. Unusually sound sleep at night (1st d.) (3). Irresis-
tible inclination to sleep in the day-time and early in the evening (2d
d.) (3). Great drowsiness in the morning after rising, having had a
sound sleep (2d d.) (30). Very reluctant to rise in the morning after
a good night's sleep (3d d.) (3). Feels as if he should fall asleep while
walking in the street in the afternoon (2d d.) (3). 80» Stupor in the
morning notwithstanding a good sleep all night (3d d.) (30). Very
sleepy but cannot fall asleep (2d d.) (30). During sleep a sensation as
if he would have a headache when awaking in the morning. During
sleep dreams of danger, especially of danger on the water (5th d.) (1).
On awaking in the morning sensation as if the head were swollen
(lstd.)(l). t
FEVER. Normal pulse being 55, is accelerated to 68 in the morn-
ing (1st d.) (1). Normal pulse being 55, is accelerated to 68 in the
214 A? y senicum-metallicum.
morning (2d d.) (1). 85. Normal pulse being 55, is accelerated to 08
in the morning (1st d.) (30). Normal pulse being 55, is accelerated to
68 in the morning and falls down to 53 in the evening (2d d.) (3).
Normal pulse being 55, is accelerated to 68 in the morning and lowered
to 43 in the evening (4th d.) (l). Normal pulse being 55, is now 12
in the morning, 64 in the evening (5th d.) (1). Normal pulse being
55, is now, in the morning, 64, in the evening 48 (1st d ) (30). 90.
Pulse after midnight 48, in the morning after rising 68 (3d d.) (30).
Pulse 64 in the morning (4th d.) (30). The pulse continues to rise in
the morning and to fall in the evening for 30 days longer, without
taking more medicine.
5. JRemarks on the Foregoing Provings, by C. Heeing, M.D.
The proving of metallic arsenic is of the greatest consequence to
the scientific development of our Materia Medica. It will furnish
answers to questions of fundamental importance.
Christison says in his Index : " Arsenic acts in all its chemical forms
except in its metallic state? (American reprint, page 230). " In con-
formity with what appears to be a general law in toxicology, the metal
itself is inert?
The foregoing provings are sufficient to satisfy even the most scepti-
cal that the metal is not inert, and it would be absurd to re-assert the
inertness of metallic arsenic and deny or reject our experiments with-
out at least repeating them.
As regards the " general law in toxicology," we have only to say
that it is a fair example of what have been styled general laws, and
even of most of those which have been called " special laws." So-
called experiments, rude and rough, in which a few rabbits, cats or dogs
have been tormented, either to death or not to death, in the coarsest
possible way, such is the ultima ratio of " toxicology." Christison
furnishes proof of this by quoting : " Bayen and Deyeux, however,
found that a drachm, carefully prepared, might be given in fragments
(!) to dogs without injuring them ; and they once gave a cat half an
ounce (in fragments ?) without any other consequences than temporary
loss of flesh."
I should think loss of flesh was something like an effect, as it very
likely appeared rapidly or it would not have been regarded at all ; be-
cause the * general law" in Orifila's "model" experiments and in
nearly all the rest seems to be, that what does not follow within a few
minutes does not follow at all. The giving metals in the form of frag-
ments, i. e., little pieces, in order to test " a law," is, to say the least, a
childish experiment.
We know that all metals, i. e., every one thus far proved, in the
metallic form and in the state of the finest powder, not only produce
decided effects, but symptoms of longer duration and characteristic
peculiarity.
Dr. Hering's Remarks. 215
*o
Aurum, Argentum, Stannum, Zincum have been proved by Hahne-
mann and others ; and Platinum by Stapf, to which have been lately
added Cadmium, Palladium, Osmium, Tellurium, &c.
Notwithstanding the repetitions of these experiments by others, for
instance the proving of metallic silver by Huber, with the same results,
the old school takes no notice of it. With a stubborness which borders
on stupidity they stick to their " general laws," no matter how much
they are shaken by all the new discoveries in the natural sciences, nay
even by their own experience. While I was attending Schonlein's
clinical lectures in the hospital at Wirzeburg, I induced a fellow-student
to make an experiment with triturated gold, which, he said, was abso-
lutely inert. A few days after, he was obliged to keep his room, hav-
ing an awfully swollen red nose, exactly confirming Hahnemann's ob-
servation. He is now a professor and a man of importance in patho-
logy, but he keeps his mouth shut ; he has not the courage to come out
and acknowledge the truth ; he is afraid to come forth as a witness,
afraid to touch the superstitions of the age. He will not read this re-
proach, but even if he should, his face will not turn as red as his nose
was ; he is hardened like the rest.
Christison, in the same paragraph, says; " Of the different prepara-
tions of arsenic it may be said, in general terms, that those are most
active which are most soluble." And further: " It is difficult to put
this — the inertness of the metal — fairly to the test, because it is not
easy to pulverise the metal without a sufficient quantity being oxidated
to cause poisonous effects.
Both assertions are worthy of consideration, as they have had much
influence even in our homoeopathic pharmacy. I will only remark that
Christison seems to have forgotten that the sub-oxide of arsenic is as
insoluble in water as metallic arsenic, and thus ought to be considered
as inert. And he does not know that arsenious oxide (AsO 3 ), the
arsenic of the shops, which is less soluble than arsenic acid (AsO 5 ),
acts with decidedly more violence than the latter. It seems to be the
same with sulphur, in its corresponding oxidations, and with phospho-
rus. If a healthy person takes, at proper intervals, the different grades
of oxidation, the highest will always be found to act the mildest. But
we will not declare this to be a general law, until further experiments
have been made.
We will now consider the two very important rules of the old school ;
1. Solubility as a condition of effect.
2. Oxidation of the metals as a condition of increased effect.
The fluid state is favorable if violent symptoms are to be produced in
a short time. It is an old chemical law : corpora non agunt nisi fiuida.
The immediate production of violent effects is the result of chemical
action; some essential and constituent parts of the body are to be
destroyed by chemical action; and it may be that such effects are
dependent o"n the fluid state of the agency. But effects, in general,
must be ascertained by experiment, separate from the experiments
which test the solubility of the agent. It would require a long series
216 Arsenic um-metallic um.
of experiments to enable us to reach a sound conclusion, that the effect*
observed were dependent on the solubility. The one has thus nothing
to do with the other. Suppose we were even to allow the conclusion,
we have still no right to conclude, negatively, that what is insoluble is
inert.
The most striking fact against the inertness of insoluble substances is
afforded by osmic acid. Any one can soon ascertain that it has an
effect, by inhaling it through the nose or trying it in the stomach. But
as soon as it comes in contact with organic matter it is decomposed, and
metallic osmium or its sub-oxide blackens the mucous membrane. As
both the smell and the effect are peculiar, the latter cannot depend alto-
gether upon the mechanical influence.
The only conclusion, then, which can be drawn from the experiments
of the toxicologists is, that that which is soluble produces an effect; to
conclude the converse, that that which is insoluble can produce no effect
at all, is, like all hasty negative conclusions, not only unwarranted, but
extremely foolish and injurious.
Every chemist knows that the experiments hitherto made in regard
to solubility are very imperfect, meagre, and insufficient ; and until the
vital importance of an accurate knowledge of the different degrees of
solubility is seen by the chemists, it will be in vain to expect them to
undertake the lonff and tedious labor of searching: for the laws of solu-
bihty.
It is known that solubility has relations to the temperature, the mo-
tion or shaking and the quantity of the solvent. Small proportions
have not been sufficiently regarded.
Sobrero, when he saw that his oil — which I have called Glonoin —
precipitated in water, inferred that it was insoluble in it. Dr. Zum-
brock, taking such water and feeling the powerful influence, analysed
and measured it accurately, and found that 0.128 parts of Glonoin are
soluble in water at a medium temperature.
The solubility of mercury in water is still denied, but the decided
mercurial effect of water boiled with mercury allows no doubt on the
subject. But the chemists, accurate as they are, have generally been
too hasty in denying such facts as may fall within the errors of obser-
vation. Liebig himself came to the most absurd conclusion, that as the
homoeopathic doses fell within the unavoidable errors of the scales, they
were nonsensical things ; as if the errors of chemical observation had
anything to do with the observation of effects on the living ! At the
same time he is perfectly aware that plants contain substances taken up
in such small quantities that no chemist of our days can discover a trace
of them ; fluoride of calcium exists in the teeth in sufficient quantity to
be detected, and must be derived from plants, in which no chemist could
detect it. It would be unscientific to suppose that fluorine forms a part
of a plant, without any other function or use than that cattle may use
it to give hardness to their teeth. As plants contain it, they must re-
quire it for their own existence, and to say that it is merely accidental,
would only be a higher degree of absurdity. Whatever has a function
Dr. Bering's Remarks. 217
must be capable of producing an effect, and as it has a function in
quantities falling within the admitted errors of chemical analysis, simi-
lar quantities must be powerful enough to produce effects.
It is a well known fact that a solvent saturated with one siibstance is
still capable of dissolving a certain proportion of another and even of
several others in succession. For instance, if we take 8 ounces of water
and saturate it completely with sulphate of iron (FeOS0 3 c. aqu.),
which will require 9£ ounces, we can afterwards dissolve in the same
solution li- ounce of the sulphate of magnesia, and the liquid will still
take up three ounces of sugar, and perhaps other substances after this.
While every one is familiar with this, there is another fact not so well
known, which is one of the most important in chemistry, and will
explain innumerable phenomena in organic chemistry, physiology and
especially in the science of effects or Materia Medica.
Sometimes the presence of one substance in a solution will increase
its power of dissolving another, or if one is already dissolved, another
may not only be added, but in increased quantities. Lithia is the least
soluble in water of all its relatives, ammonia, potassa and soda ; but its
solutions will dissolve urates, which are insoluble in pure water. Uric
acid, the morbid product, which causes, besides innumerable other
troublesome symptoms, gravel in the kidneys, stones in the bladder, and
the deposits on the joints of the fingers in gout, and which is formed
and kept in solution in the blood and urine under conditions of which
we are ignorant, requires 10,000 parts of water for its solution. In a
solution of carbonate of potassa the solubility of some urates and uric
acid increases about a hundredfold ; in a solution of carbonate of soda
it doubles, and in a solution of carbonate of lithia it doubles again.
Lithia being the least soluble among its relatives (only 1 to 1,000),
increases the solubility of uric acid in water four hundredfold. The
same quantity of water which would have dissolved T $ 7 part of a grain
of uric acid will, after one grain of carbonate of lithia has been dissolved
in it, receive 4 grains of uric acid.
This opens a field for the most important researches, and until it has
been sufficiently cultivated, we have no right to say of any substance
that it is insoluble in the fluids of the organism ; and it iB evidently
perfectly absurd to contend, that because it is insoluble in water it is
therefore inert when introdnced into the vital economy.
Cinnabaris is rejected by the so-called rational schools, 1st, because
we do not know of any agent capable of dissolving it in the animal
body, and has been declared by the toxicologists not to be " possessed
of any deleterious action of the animal body," founded on the disgust-
ingly absurd experiments of Orfila. These philosophers are themselves,
however, so much the subjects of deleterious action that they can reason
backwards; thus, in the experiments of Smith, who found that the
Cinnabar acted, an impure article was used. It is possible, and even
probable, that the high estimation in which Cinnabar was held by the
ancients in a great many diseases, may have resulted from its containing
arsenic ; but even a mixed sulphuret and arseniuret of mercury is not
218 Arsenicum-metallicum.
capable, so far as we know, of being dissolved by any agent present in
the body.
Ten years ago I took a trituration of chemically pure Cinnabar, and
observed a most decided and unmistakable action. I repeated the
experiment several times ; the 3d trituration always acted the same
day. Others repeated those experiments with nearly the same results,
particularly Dr. Lippe, who observed the same peculiar congestions of
the head which we have ever since permanently cured in a number of
cases.
Finally, Dr. Neidhard undertook to prove the Cinnabaris, fully, with
the assistance of the students of the Homoeopathic College in this city,
and with such a brilliant result that it is now one of our most important
and best proved medicines.
Still we do not know any agent in the animal body capable of dis-
solving Cinnabar, but we know with a certainty equal to any other in
natural sciences that it acts upon the organism, and we know the mode
of its action so that we can make use of it as an agent to cure the sick.
Shall we reject it and wait until chemists please to detect "an agency
capable of dissolving it in the animal body ?"
Having shown that solubility, or what is known about it, has no
conditional connexion with effect, as the latter must be ascertained
separately by independent experiments, we have now to consider the
remaining point, oxidation as a condition of increased effect.
It is said that arsenic is not easy to pulverize without a sufficient
quantity being oxidated to cause poisonous effects. We have already
remarked that if solubility is required, the sub-oxide of arsenic being
also insoluble, the oxidation explains nothing. But, it is also too hasty
a conclusion to say, that oxidation necessarily follows pulverization.
It is true, most metallic arsenic in damp air changes into a black pow-
der which is supposed to be AsO. ; but better prepared metallic
.arsenic does not, especially not in dry air.
I expect to decide the question very soon, if time will allow me to
--examine the trituration of metallic arsenic which was used in Lippe's
experiments by the microscope, as the metallic particles will be seen
either with the strong splendor and tin-whiteness which this metal
possesses, or with the dull black color of what is called the sub-oxide.
It may be both are mixed.
But let us suppose that it is in the condition of sub-oxide ; does that
explain its efficiency ? "We know that a great many metals do not
combine with oxygen if pulverized or triturated according to our way of
preparing ; with some metals it is even a difficult thing to produce a
combination with oxygen; some combine with rapidity even when
simply exposed to the air. We know the first mentioned class to act
powerfully,- and we know the latter would poison or destroy parts of our
organism, if brought in contact with it in the metallic state. Between
these two extremes lie all the rest, some oxidizing rapidly, some slowly.
We know of some that they have a decided effect, notwithstanding
ithey are reduced to the metallic state in the body ; thus while the
Dr. Ilering's Remarks. 2T9
opposite process takes place. Furthermore, we know tliat those which
act in the metallic state — like mercury — will act in the state of oxides
— red precipitate — but it would be preposterous to assume that they
acted more violently in the latter state. We refer to the case reported
by Burnett in the Philosophical Transactions, 1823, page 402, where
the whole of 200 persons on board of two ships and all the animals on
board were poisoned by mercury ; there being in the hold of the vessels
leather bugs rilled with quicksilver, of which some had burst. As we
know that mercury is soluble in air in the metallic state, and even that
a small quantity of quicksilver in a bottle will amalgamate a gold leaf
hanging from the stopper (Faraday), it requires the stubbornness of an
old school doctor to suppose oxidation necessary in order to produce or
explain these effects.
Not a single series of experiments has ever been made, to prove that
oxides act more readily than their metals.
We would not have spoken of such absurdities of the old school had
we not before us propositions to introduce into Homoeopathy the oxides
instead of the metals. We refer to Oesterreichische Zeitschrift, Vol. L
No 1, p. 174, where several reasons are given, not one of which will
stand real criticism.
We come now to a proposition of some consequence.
We all know that every drug taken by a prover or a patient, may
undergo chemical changes sooner or later after it comes in contact with
the body. We know, beyond a doubt, of some substances, that as soon
as they come in contact with animal tissues or fluids, they combine with
them or are decomposed. We know of some, that they are not, and of
others that they are, expelled unaltered, from the body ; of a great
number we do not know, but have a full right by a sound a .alogy to
conclude, that they also will. We know there are no exceptions to a
mathematical rule; the same is the case with natural laws, so-called'
exceptions being only apparent, and if properly studied either confirming
the law or proving that it is no law. Every substance will follow the
laws of chemical affinity, in contact with unorganiz d bodies as well as
with organized. As fast as careful researches are made, apparent
exceptions always disappear. It has been supposed, for instance, that
the organism could produce chemical elements. Car ful experiments
have shown clearly that it cannot. It has been supposed that chemical
laws were overruled by the dynamic influence or life, as by something
higher, and were obliged to submit, but there is not a single, fact known
to confirm this.
It is the manifold influences present in organisms, the great combi-
nation of influxes, which ma'iea it rather a difficult problem, in some
instances, to decide. Sill, in every case in which the scrutiny of na urai
philosophers has been directed to such a que ton, the answer, without
exception, has confirmed the higher power of the chemical laws.
Thus, every substance taken by a prover or given to a patient, as
soon as it comes in contact with the tissues or fluids, will follow its
chemical laws. - • *•-»<
220 Arsenicum-metallicum.
Single elementary substances will combine with others if they meet
them and have an affinity for them. Nitrate of silver is immediately
decomposed, and the metal forms an albuminate of silver ; the nitric-
acid, a nitrate of albumen ; both, we are allowed to suppose, are dis-
solved ; the first, certaiuly, enters the blood and is deposited in the skin,
the second, if dissolved, is decomposed and nitrates of the alkalies
formed. What we call the symptoms of nitrate of silver is thus the
combined effect of these two or more combinations. Single elementary
substances may combine with oxygen, hydrogen or carbonic acid, or
with other free acids or alkalies ; or they may decompose some of the
parts of the animal fluids or tissues.
If a certain substance combine with oxygen and is oxidized, either
by taking the oxygen from air or water, or other contents not essential
to life, the effect of such a substance taken in a chemically pure state,
must be identical with the effect of the oxide, and it would be indifferent,
whether we give the patient the one or the other.
If a certain substance combine with hydrogen in the system, the
effect will be the same as if this combination had been taken. As there
is an essential difference between the combinations of an element with
hydrogen, and of the same with oxygen, it is a question of great impor-
tance to know which will take place, or, if both are possible, what art
the conditions for the one or the other. According as the one or the
other happens, the opposite cycles in the time of the day, and the oppo-
site direction with regard to the sides of the body in electro-positive or
negative bodies, would be manifested in such combinations. The gaseous
hydrogen combinations would act like alkalies, the oxygen combinations
like acids ; this I suppose to be a fundamental law in Materia Medica.
The difference between the effects of carburetted hydrogen and car-
bonic acid, is as great as a difference possibly can be. There is, in fact,
no similarity whatever. It is like the difference between ammonium
and nitric acid.
Sulphuretted hydrogen acts also very differently from sulphurous or
sulphuric acid, and we should not suppose it could be the same sub-
stance in both, if we did not know it.
Arseniuretted hydrogen acts very differently from arsenious acid>
according to the cases of poisoning and to my own provings, but the
difference is not as wide as in the case of carbon and sulphur.
We may conclude that the other corresponding combinations have
also more differences than similarities ; thus, phosphuretted, seleniuretted,
and telluretted hydrogen have very different effects from phosphoric,
6elenic, and telluric acids.
Thus if the same substance can combine in the body with oxygen or
hydrogen, there must be a considerable difference in the effects.
Sulphur applied to the skin, for instance, as a powder put in the
stockings under the soles of the feet, combines with hydrogen, and is
expelled as sulphuretted hydrogen from the skin and the lungs. It is
this experiment which induced me to propose it as an antidote or pre-
ventive to Asiatic cholera (1833).
Dr. Hering's Remarks. 221
The books will tell us that sulphur could not exist iu the blood as
sulphuretted hydrogen ; that the sulphur would be changed into sul-
phuric acid and form sulphates. All this is not sufficiently proved, but
the combination with hydrogen is a certain fact, and can be ascertained
by experiment. It may be that under certain conditions the one, and
under other conditions, the other affinity would come in play, and if so
we ought to know what these conditions are.
While proving the tellurium in the metallic state, I had reason to
suppose it had combined with hydrogen in the body. The same may
have been the case with selenium. It may be the same with metallic
arsenic, or it may be not ; the similarity between the effects of arse-
niuretted hydrogen and metallic arsenic may have another cause.
According to a French chemist, arseniuretted hydrogen is decomposed
by contact with the animal tissues, and metallic arsenic is precipitated.
Experiments would soon decide the point, and whether the combination
take place or not, the metal would probably be our best agent. At all
events it is theoretically and practically a question of importance to
make the following series of provings and comparisons :
inTDROGEN.
ELEMENTS.
OXYGEN.
Sulphuretted Hydrogen.
Sulphur.
Sulphuric Acid.
Seleniuretted "
Selenium.
Selenic Acid.
Telluretted "
Tellurium.
Telluric Acid.
Phosphoretted "
Phosphorus.
Phosphoric Acid.
Arseniuretted "
Arsenic.
Arsenic Acid.
Antimoniuretted "
Antimonium.
Antimonio Acid.
Carburetted "
Carbon.
Carbonic Acid.
Those in italics have been already more or less proved.
The practitioner already finds a remarkable difference of effect between
sulphur and sulphuric acid, between phosphorus (which changes mostly
into phosphorous acid while preparing it, or after its contact with the
mucous membranes) and phosphoric acid. We have reason to suppose
this will be the case with the other acids.
The combination of the same substance with hydrogen must give us
very important medicines, not only on account of their quickness and
intensity of action, by far superior to the effects of the uncombined
elements or the acids, but especially on account of their very marked
and characteristic differences. Their general characteristics must be not
only different, but opposite, and what we know thus far of the sulphu-
retted and arseniuretted hydrogen confirms this. The diseases in which
the acids are of use, are of an opposite character to such as are helped
by the hydrogen combinations.
The Red Sulphur Springs of Virginia are famous for " reducing the
pulse;" it is the slow development of small doses of sulphuretted
hydrogen in the stomach on which this effect depends, as experiments
with sulphuretted water have proved.
The difficulty, and in some instances the impossibility, of using the
other hydrogen combinations, have hitherto prevented their introduc-
tion into our Materia Medica. If we should prescribe such mixtures as
222 Arsenicum-metallicum..
would produce the gas in the stomach, we should have a mixed effect.
The very ingenious apparatus of Drysdale (British Journal, 1 ', 559;
8, 152;) has overcome the apparently insurmountable difficulties, hut
it is only for such desperate cases or diseases as cholera and the like.
My experiments with the arseniuretted hydrogen have shown in 1846-7,
that the millionth of this gas, taken by inhalation, caused a dangerous
illness, lasting several weeks. But experiments could be made wiih
still smaller doses, and this difficulty overcome, and we intend to do it
as soon as possible.
Still, on either supposition, that metallic arsenic forms arseniuretted
hydrogen in the body, or that arseniuretted hydrogen is decomposed in
contact with the tissues, depositing metallic arsenic, it would be better to
use Metallic Arsenic, at least in chronic diseases.
The proving of Metallic Arsenic has been one of the most important
steps towards the solution of this question, and as soon as my time will
allow, I will publish the known effects of the arseniuretted hydrogen,
and a comparison on the one hand with arsenious acid, and on the
other with Metallic Arsenic.
It would be of great service in these investigations, if we could find
provers to repeat and augment the experiments; the 3d trituration acts
very strongly, and I wouid recommend that preparation, as the effects
are of long duration. I will, with great pleasure, supply any one With
the drug who wishes to assist in repeating the pro\ings.
9.— AKTEMISIA-VULGAKIS.
ARTEM. Mug wort.
1. Description and Preparation.
This common and very bitter plant belongs to the large natural
family of Composite. The American A.-vulgaris is thought by
Nuitall not to be identical with the European species - they are how-
ever, very similar.
The whole plant should be gathered at the season of flowering and
the juice expressed.
Asterias-rubens. 223
2. Knoioledge of its Effects.
We have as yet no provings of the Artemisia, though it is much to
be desired that some were undertaken. It is a popular remedy in
Germany against Epilepsy, and has been used in many cases with
success ; in Catalepsy and Somnambulism ; in Chorea and in one case
of Strangury.
Noack and Trinks give the following summary of what is known
about it. Arzneimit. 1, 141.
Aggravation of the epileptic paroxysms. — Excitement of the nervous
system. — Profuse, specifically foetid, putrid, garlic-smelling sweat. —
Violent contractions of the uterus ; labor-pains. — Prolapsus, rupture of the
uterus. — Abortion. — Profuse menstruation ; metrorrhagia. — Increased
flow of the lochia.
10.— ASTERIAS-RUBENS
AST. Star-fish, Sea-star, Finger-fish. Fr. Etoile de Mer.
1. Description and Preparation.
This well-known animal belongs to the general division Radiata,
class Fchinodermata. It is very commonly found on the sea-coasts of
France and England. It has five fingers or rays symmetrically disposed
about a common centre, the under surface of which contains the mouth
of the animal. Their anatomy has been most patiently and minutely
investigated by Tiedemann. The calcareous coat, with the numerous
spines and processes, was found by Mr. Hatchett to consist of carbonate
of lime with a little phosphate of lime.
Dr. Petroz, who has given us the proving of this remedy, has unac-
countably omitted to state how his preparation was obtained. The
entire animal was probably brayed alive in a mortar until it was
reduced to a magma, which was then digested with alcohol to produce
a tincture. A better mode would be to triturate the magma with
sugar of milk.
2. Digest of the Symptoms.
AUTHORITIES. Dr. Petroz {Journal de la Societe Gallicane,
vol. 1, p. 225) states the following provers. 1. M. P. 2, M. P. J. 3,
M. T. 4. M. M. 5, Mad. B. 6. Mad. T. 7. Mademoiselle M.
Q
224 Aster ias-rubens.
MIND. 1. Sadness alternating with almost insupportable cerebral
excitement ; she is desirous of undertaking some intellectual or corporeal
labor, walking or taking violent exercise ; this state has no resemblance
to that produced by spirituous liquors, it is rather a moral intoxication ;
(2d and 3d days) (7). Slight disturbance of the intellect with general
weakness ; (6th day) (2). Feeling of extreme anxiety from noon to
three o'clock ; it seems as though some misfortune were impending, as
though some bad news were about to arrive ; then tears are felt to be
a relief; (6th day) (4). Irritability, anger, necessity of quarrelling
with somebody; from noon to 2 p.m. ; (6th day) (4). 5. Depression,
ennui, he thinks he is about to meet with misfortune ; he perceives that
if it should arrive, he would sooner weep than fret or get angry ; (6th
day) (4). The symptoms disappear by degrees, leaving behind them a
moral sensitiveness that impels him to weep under the influence of the
least emotion ; (11th day) (1). Extraordinary gaiety in the evening ;
(1st day) (6). Tears, with despair, succeeded almost immediately by a
calm ; (3d day) (7). He does not like to work in the afternoon ; (6th
day) (1).
HEAD. Vertigo. 10. Transitory vertigo (3). Vertigo when
walking; (1st day) (3). Vertigo; (10th day) (5). Fulness and
Heat. Sensation of fulness as though from congestion, and sometimes
even as if from a rush of blood to the head ; (2d day) (7). Determi-
nation of blood to the head, sensation of fulness, heat ; it feels as if it
would split ; (2d day) (7). 15. Heat in the head ; it seems as if the
air about her head were hot; (1st day) (7). Heaviness of the head;
after one hour ; (1). Heaviness of the head, heat, throbbings, redness
of the face ; (1st day) (1). Fulness of the head, which seems to distend
the sides of it ; (1st and 2d days) (7). The blood determines more
strongly to the head; (4th day) (7). Forehead. 20. Acute, transi-
tory lancinations in the forehead and temples, especially in the occiput ;
(1st day) (3). Pressive pain in the forehead, sensation of fulness,
contraction of the muscles and pressive constriction above the eyes ; (1).
Violent pressive pain in the sinciput, in the morning ; it is with diffi-
culty dissipated in the course of the day by a walk in the open air ;
(7). Very violent pressive pain in the forehead, above the eyes ; (4th
day). Violent pressive pain in the forehead which seems to crush the
eyes by an enormous weight ; (4th day) (7). 25. Boring pain above
the left eye, coming and going suddenly, and producing contraction of
the eye-brows ; while this pain lasts she seems to look through a mist ;
(2d day) (7). Head generally. Feeling of distress in the brain ;
(1st day) (1). Transitory pain in the right half of the head; (3d day).
Sudden pain on the right side of the head ; (3d day) (7). Slight
lancinations in the brain ; (7). 30. Lancinating pain in the right
temple ; (2d day) (5). Lancinations in the brain, when blowing his
nose, during the first half of the night; (4th day) (3). The headache
disappears suddenly towards noon and the ideas are clearer; (7).
Pressive pain on the right side of the occiput, making it difficult to
walk ; (5th day) (7). Pressure in the temples ; (1st day) (3). 35,
Asterias-rubens. 225
Throbbing in the head ; (2d day) (7). Throbbing in the head when
ascending or walking ; (2d day) (1). Pain, during the continuance of
which her head seems as though it were being crushed ; (3d day) (7).
Pain in the vertex as if the skull would break ; (3d day) (7). He
wakes in the night in great distress ; it seems to him as if his brain
were shaken by electric shocks, his head seems empty, almost deprived
of consciousness ; thinks he is attacked with apoplexy (night between
the 6th and 7th day) ; this lasts several minutes ; when he recovers his
consciousness his pulse is hard and much accelerated ; the right carotid
beats violently ; this febrile state continued to the end of the next day ;
(2). 40. During the severe pains the whole cranium is sore ; (5).
The headaches increase towards afternoon and oblige her to go to bed ;
they are more violent behind than before, the head is painful all night ;
(9th day). Agitation, spasms, sense of uneasiness in the upper part of
the brain, especially on making a mental effort ; the feeling is similar to
the feeling of lassitude in a limb the muscles of which have been
severely exercised; (10th day) (5). Difficulty in enduring labor in the
afternoon ; (6th day) (1).
EYES. Heat in the eyes; (1st day) (7). 45. Bloodshot eyes;
(4th day) (1). Light fatigues the eyes; (1st day). Difficulty in
bearing the light; (4th day) (7). The eyes are drawn backwards;
(3d day) (7). Fatigued look. 50. Twitching of the lids, the edges
are red ; (7th day) (7). Pain in the eyes from within outwards ; (7th
day) (7).
NOSE. Epistaxis; (9th day) (1). Epistaxis renewed three times
in five days ; (2). Sneezing and coryza on waking in the morning ;
(9th day).
EARS. 55. Lancinating pain in the meatus, perceived for some
seconds, is concentrated in the occiput, and ceases ; these pains returned
in the course of the day, but less violently; (3d day) (3). Sudden,
very violent noise in both ears lasting less than a second; (3d day) (3).
Dulness of hearing, more marked on the right side ; (2d day) (5).
Dulness of hearing, noise of rushing of water in the ears ; (7th day) (l).
FACE. Face red ; (4th day) (5). 60. Face red and swollen ; (3d
day) (5). Stupid look, a stupid expression in the attitude and look ;
(7th day) (5).
MOUTH. Swelling of the tongue ; (3d day) (5). Drawing pain in
the tongue (o). Embarrassment of the tongue, dislike to speak ; (5th
day) (5). 65. Saliva more abundant, disposition to bite ; (5th day)
(5). Irritation of the throat, short-lasting sensation of heat; this feel-
ing returns several times during the day ; (1st day) (2). Irritation of
the throat, at first* very slight, becoming more perceptible on the 5th
day (5). Dryness of the throat ; (6th day) (5). Sore throat (con-
striction) on waking in the morning ; (8th day).
APPETITE. 70. Want of appetite, no taste; (4th day) (7).
Disgust for meat; (7th day) (1). Capricious appetite, she desires
highly seasoned dishes, strong cheese, liqueurs, coffee, tea ; (8th, 9th,
10th days) (7).
226 Asterias-ruhens.
STOMACH. Dull pain extending the whole length of the oeso-
phagus ; (1st day) (3). Frequent forcible eructations in the morning ;
(1st day) (1). 75. Nausea ; (2d day) (l). Weariness and great heat
in the stomach in the morning, with many violent eructations ; (7th
day) (1). Dull pain in the muscles of the precordial region ; (2d day)
(3). Constriction in the precordial region (4).
ABDOMEN. Dull pain in paroxysms in the right side of the
abdomen near the navel ; (7th day) (1). 80. Flatulence after every
meal, which is very troublesome, as it cannot be expelled either upward
or downward ; (3d day) (7). Violent colic, with shivering, alternating
with flushes of heat in the face ; (5th day) (7). Alternation of swelling
and diminution of the abdomen during the twenty-four hours ; (3d
day) (7). Drawing in the abdominal walls ; (3d day) (7).
RECTUM; ANUS; STOOL. Heat in the rectum. 85. Slight
hemorrhoidal swelling ; (3d day) (7). Hemorrhoidal flow, lasting two
days ; (5th and 6th days) (7). StOOl. Constipation, fruitless desire
to go to stool, a symptom she never before experienced ; (1st day) (7).
Difficult, consistent stool; (3d day) (7). Colic followed by diarrhoea;
(3d day) (5). 90. Brown, liquid stool discharged in a violent jet ;
(4th day) (5). Several soft stools during the day (4).
URINE. Frequent, limpid urine ; (2d day) (7). Frequent desire
to urinate, urine more abundant; (7th day) (1). Thick, viscid urine;
heat in the urethra on urinating; (8th day) (1).
GENITAL ORGANS. Male. 95. Frequent erections during
sleep (4). Erection in the morning; (3d day) (3). Female. Sen-
sation of pressure upon the lower abdominal organs, impeding loco-
motion ; (3d day) (7). General feeling of distress in the womb as
though something were pushing out ; (2d day) (7). General feeling
as if the menses were about to appear ; (2d day) (7). 100. Twitching
in the uterus ; (2d day) (7). Unusual degree of moisture in the vagina,
which is soothing ; (3d day) (7). Menses retarded eight days, during
all which time the colics and other sufferings which usually accom-
panied them continued, but ceased on their coming on ; they were more
abundant than ordinary. Excitement of the venereal appetite every
morning in bed ; (3d day) (7). Besieged by desires, fearful of inability
to sustain these painful sensations ; nervous commotion (3d day).
CHEST. 105. Lancinating pain in the anterior inferior portion of
the chest to the right and left of the sternum ; this transitory pain was
diminished by carrying the upper part of the body and the shoulders
backwards ; (4th day) (5). Drawing pain towards the internal part of
the chest from before backward, extending, under, the left nipple, into
the whole internal part of the arm to the extremity of the little finger ;
(5th day) (1). The whole left side of the chest is painful; motion
aggravates the pain ; (1st day) (3). Substernal pain (6). Feeling of
fulness in the chest causing fear of syncope ; (7th day) (l). Palpi-
tations. 110. Anxiety caused by undulating throbbings in the chest,
in the night (6th day). .Frequent violent palpitations. Dull palpitations,
scarcely perceptible, distant ; it seems as if his heart had ceased to beat
Asterias-riibens. 227
(4). Twitching palpitations ; (3d day) (1). When the palpitations are
most violent, they extend to the epigastrium with a sensation of con-
striction ; (3d day) (l). H5, Anxiety in the heart during the night
and morning ; (7th day) (1). External. Feeling as if the left breast
were drawn inwards (4). Drawing pain in the breast ; (2d day) (7).
Swelling and distension of the breasts as if before the menses; (3d day)
(?). Very slight eruption between the breasts (6). 120. Slight
redness with floury efflorescence on the chest ; (4th day) (7). A spot
as large as the palm of a child's hand upon the chest, causing violent
itching ; the redness disappeared at the end of five or six days (7).
BACK. Drawing pain in the sacrum (1st and 2d days). Drawing
pain in the back.
UPPER EXTREMITIES. Restlessness in the limbs, especially in the
bends of the arms ; it is scarcely endurable to have the arms covered ;
(4th day) (7). 125. Pain extending from the thumb-joint into the
shoulder (which ?) (7th and 8th day) (2). Pain in the right shoulder ;
(2d day) (3). Coldness in the left arm, it seems as if a cold wind were
blowing on it ; (3d day) (7). Pain in the left elbow joint ; (7th day)
(3). A red circular spot of the size of a franc on the left olecranon,
causing neither itching nor smarting, becoming covered with a dry,
furfuraceous, friable coat, which falls off in two days, without leaving
any mark ; a similar but smaller eruption on the anterior portion of the
same arm; (11th day) (7). Hands and Fingers. 130. Numbness
of the hands and fingers ; (6th, 7th and 8th days) (2). Numbness of
the left hand, extending into the arm ; (2d day) (7). Numbness of the
hypothenar eminence and little finger; (5th day) (4). Pain in the
flexor tendons of the left hand ; (2d day) (3). Severe itching around
the left thumb-nail ; (7th day) (3).
LOWER EXTREMITIES. 135. Lassitude in the lower limbs;
(4th day) (l). Weakness in the legs when standing so that she needs
assistance in walking ; (3d day) (5). Painful lassitude of the lower
limbs (6). Pain in the right hip and whole left side up to the scapula,
lasting to the sixth day and giving rise to fever (2). Dull pain in the
left coxo-femoral joint in the morning; (2d day) (1). 140. Burning
lancinations in the great trochanter and left coxo-femoral joint, extend-
ing like lightning into the external side of the ham ; (3d day) (l).
Same symptom ; (9th day) (5). Sensation of drawing in the right hip
as if the leg were too long and drawn downwards ; (5th day) (7).
Formication in the lower limbs ; (11th day) (1). Great uneasiness in
the lower limbs when in a closed apartment. 145. Desire for fresh air ;
(3d day) (7). Thighs and Legs. Deep lancinations in the anterior
part of the thigh; (6th day) (1). Dull lancinations in the anterior part
of the thigh ; (1st day) (5). Drawing pain on the external side of the
left thigh ; (7th and 8th days) (2). Very lively itching in the thighs
and legs, exceedingly uncomfortable, renewed towards 6 p.m. in the
open air; (7th day) (3). 150. A little excoriation on the leg caused
by scratching becomes the seat of a pretty severe lancinating pain; (8th
day) (3). Diminution of sensibility of the limbs, especially of the thighs
228 Aster ias-ruhens.
and legs ; (4th day) (3). Pain in the left knee ; (2d day) (3). Feet.
Painful drawing in the soles of the feet and toes (8th day). Pain in
the joints of the left foot ; (2d day) (3). 155. Lancinating pain in the
toes, especially in the great left toe, with very great heat and extreme
sensibility, which cannot endure the ordinary covering ; increased after
sunset and in a closed room ; redness of the skin ; it is increased by
heat ; the cold air or cold water assuages the pain at once, but the heat
of the bed renews it, although it ceases during the first part of the
night (3d day). This pain continued to appear in a troublesome
manner for several afternoons, and finally disappeared like the other
symptoms (7). Pain in the left foot, concentrated at the metatarsal
articulation of the great toe, lasting all day (6th day). It is aggravated
bv motion, renders walking impossible, and has a gouty character (3).
Acute pain in the joint of the left foot, increased by walking; (7th day)
(3). Insupportable pain in the left foot and in the muscles of the leg ;
(8th day) (3). Violent cutting pain in the left great toe, sensibility of
the left sole, toes very painful ; (3d day) (7). 160. Pain in the joint
of the right foot (6). Burning heat in the feet ; (11th day) (1). The
pains in the joints, particularly those of the left great toe, return three
days after having ceased to take the drug (3).
FEVER. Temperature. Aversion to everything which increases
the heat of the body, great desire to wash with cold water ; (3d day)
(7). Desire for the open air, anxiety, impatience of being shut up ;
(5th day) (7). 165» The general heat is increased during the whole
period of action. Fever, After the evening meal, general malaise,
heat of skin and fulness of pulse ; (1st day) (1). Violent heat in the
head, then over the whole body, desire for cold drinks and for cold
both internally and externally ; (3d day) (5). Shivering with somno-
lence, hot skin, restless night ; (3d day) (1). Heat of skin, fever
toward the close of the day, shivering, heat followed by coldness ; (10th
day) (5).
SLEEP. 170. She slept from 2 a.m. to the middle of the day ;
(3d day) (7). Agitated sleep; (11th day) (l). Need of rest and
disposition to sleep after reading a moment ; (10th day) (1). Many
dreams about persons and events ; the images are extraordinarily vivid
and lifelike ; she thinks she sees, touches and hears the persons of whom
she is dreaming as though she were awake, but without any painful
impressions ; (2d and 3d days) (7).
GENERAL. General malaise, lassitude ; feels better after eating.
175. The symptoms are aggravated in the after-part of the day, espe-
cially in the evening. Great lassitude from heat, especially the heat of
the bed. It is difficult to remain doing nothing.
3. Clinical Remarks.
Some clinical remarks on the Asterias, with illustrative cases by
Dr. Petroz, may be found; iV. A. Horn. Journ., vol. 2.
Provings of Oinndbaris. 229
11.— CINNABARIS.
BY C. NEIDHARD, M.D.
CINNAB. Cinnabar, Vermilion, Sulphuret of Mercury, Hydrargyri
sulphuretum rubrum.
1. Preliminary Remarks.
Our annual conventions are friendly and pleasant gatberings of the
friends of our cause from various sections of the country. Eloquent
addresses have at least informed the people, that Homoeopathy is not
yet defunct, as it has been predicted it would be, for the last twenty
years. But have they been really able to effect anything for the
general advancement of homoeopathic science, as was their principal
duty to do ? Where are the provings which would confirm the symp-
toms of our Materia Medica ? Where are the proviDgs of new
remedies, as still many diseases occur for which no homoeopathic
simile has been discovered ? Where are the monographs of individual
diseases enriching its archives ? Has there ever been a well-concerted
plan for the advancement of our cause submitted to the convention,
that has been thoroughly acted out ? To all these questions a negative
answer must be given. Under these circumstances each one must
work in bis own individual sphere as far as he is able, and admonish
all those with whom he may have any influence to do likewise.
By doing everything we can for the scientific improvement of
Homoeopathy, we can best and most permanently establish our own
success. But when had the morally benighted ever intellectual insight
enough to understand this simple truth ?
It has been for some time my desire to make a series of provings
with substances which are found in a naturally compound state, as
being probably better calculated to eradicate the many complicated
chronic diseases, than the simple substances. A number of stu-
dents, perceiving the importance of the step, were at once willing
and ready to engage in these experiments. It is my plan to prove
every year one or two of these compound remedies of either entirely
new substances or such as have only been imperfectly experimented
with before. Occasionally, also, an American plant will be proved.
230 Cinnabaris.
I have commenced with Cinnabaris, because the experiments of
Hahnemann with this remedy were but few in number, and he had
expressed a wish to have them perfected.
The symptoms contained in the following provings were principally
obtained from the 30th and 6th dilutions and from the 3rd trituration,
centesimal as well as decimal.
My main object was to enjoin upon the provers, to record the symp*
toms in the order in which they experienced them, so as to obtain a
complete history of the pathogenesis of the remedy. Another impor-
tant point with me was, that no new dose should be taken by the prover
so long as symptoms were felt from the first dose.
The difficulties to be encountered in establishing, on paper, an
efficient arrangement, are not a few. It would have been no doubt
easier to separate the different symptoms belonging to each organ.
But as this could only have been effected at the risk of omitting
many important groups, by which alone the action of the remedy in
different organs is to be perceived, I preferred the laborious task of
tracing the connection of the symptoms in all the organs, as far as
possible. Whatever symptoms, then, the different provers experienced
at the same hour or hours, or which returned after a certain interval of
time, at the same time, have been grouped together in the order in
which they appeared, however remote from each other might be the
organs affected.
I would suggest, that an analysis of the symptoms of a remedy may
be made in the following manner : — Place the heads of the different
organs on single sheets of paper, as head, eyes, mouth, etc., etc., and put
down at once every group, that has some reference to each organ.
The same may be done with regard to the conditions. By these
means we may save a great deal of writing and re-writing.
My conviction is, that the progress of the Homoeopathic Materia
Medica can better be promoted by still more accurate provings,
and faithful provers, than by any other method.
2. Description and Preparation.
The Cinnabaris I employed in the following provings was care-
fully prepared by Mr. John, apothecary. I should have preferred, as
I do in every instance, to have proved the native Cinnabar also, but I
was unable to obtain any. According to " Schrceder's Arzneischatz :"
Cinnabaris consists of mercury one part, sulphur two parts, well tritu-
rated together and heated.
The native Cinnabar is of the same nature as that prepared by art,
and is only distinguished from it by its stony part varying according
to the mines in which it grows. The best is said to be found in the
Hungarian gold mines. That which is found near the city of Grems
(Kremnitz?) is preferred to others. The natural is often suspected
because it contains particles of arsenic. According to modern writers
Provings of Cinnaba/ris. 231
" the best-defined crystals are found in the coal formation of Moschel,
Landsberg and Wolfstein in the Palatinate* * * *
Well-crystallised specimens are mentioned also from Japan, Mexico,
and Brazil. The principal repositories of this ore, however, are
Almaden in Spain and Idria in Carniola, where it occurs almost exclu-
sively massive, and whence it is obtained in large quantities, as. an ore
of mercury." — Alger's Phillip's Mineralogy.
3. Provings.
Precaution was taken that none of the provers should be acquainted
with the remedy he was experimenting with, until all the provings were
finished.
First Proving.
Dr. Smith Armor. — 1851. January 25th. — Six hours after taking
ToVo P ai 't °f a grain of Cinnabaris had a rumbling through his
abdomen below the transverse colon, which lasted about one hour and a
half.
Jan. 26th. 2d dose. — Taken in the morning, and in three or four
hours after, his abdomen, below the transverse colon, felt hot, his tongue
is covered with a white fur, and there is a beating burning in both
temples, which he felt all day.
Second Proving; Sixth Attenuation.
A. J. Brewster, aged 26, enjoys good health.
1851. Jan. 11th. Took at bed-time twenty pellets of the sixth
dilution of Cinnabaris.
Jan. 12th. In the morning a sense of general prostration, great
weakness of all the limbs. Feeling of depression and weakness of the
whole system as after a severe illness. Indisposition for mental labor.
The head feels weary as from long mental application — a dull heavy
ache in the front of the head ; from the front to the back of the head,
mostly over the right eye and temple, heat in the head. Occasional
darting pains through the head from without inwardly.
Eyes watery and dull, with a sharp sticking pain in the inner canthus
of the left eye, as of a sharp stick being stuck in the lower lid.
Loss of sleep during the fore-part of the night. Restless and tossing
about during the whole night, with anxious dreams, which he is
wholly unable to recall after awaking. Nausea with occasional throb-
bing in the left hypochondrium. Abdomen distended, stools hard and
too large.
Dull aching in the bones of the forearms and legs. Numbness in
the left arm from the elbow to the end of the little finger, passing off
on using the arm, and returning again while at rest.
In the morning appetite greatly impaired. But little appetite for
breakfast after taking the remedy the previous night. Feels better in
the open air and after dinner. Pulse 60, skin moist and cool.
232 Cinnabar/'*.
Third Proving ; Third Trituration.
A. J. Brewster. 1851. Jan. 22nd. Took, a quarter before 11 o'clock
A. m., 5 grains of 3rd. trit. of Cinnab. (Hahn.)
# At 3j p. m., felt a sharp steady pain in the forehead, mostly in the
right orbital region, soon after felt a sharp throbbing in the left hypo-
chondrium in the region of the spleen. At 10 o'clock p. m., felt a dull
aching pain in the bones of the forearm and legs.
Jan. 25th. Took at 11 o'clock a. m. a dose of the third trituration
(decimal scale) ; in half an hour felt a sharp aching pain in the
right supra-orbitary region, shooting backwards and downwards to the
ear and side of the neck. Front of the head very hot. The pain is
worse in the warm room and on moving the eyes and scalp.
Chilliness in the warm room. An uneasy indescribable feeling in
the abdomen. Numbness of the left arm from the elbow down to the
end of the little finger. 10 o'clock p. m. Pain in the head increased
to a heavy, stupefying ache, aggravated by thinking, reading, and pres-
sure. Tenderness of the epigastric region.
Jan. 26th. a. m. Symptoms all better. 8 p. m. The pains in
the head return, with a numbness and heavy aching in the arms and
knees and lower legs.
Jan. 27th. 11 o'clock a.m. Pains in the head return again, with
a disposition to fall asleep while listening to the lecture, several times,
notwithstanding his making a great effort to keep awake. Constrictive
feeling in the umbilical region. Urine tinged yellow.
Pains all aggravated in the evening. Better in the open air and
after eating and sleeping.
Fourth Proving ; Third Dec. Trituration.
Dr. J. P. Dake, subject to indigestion, costiveness, and a dull heavy
feeling in the fore-part of the head. Dark hair, dark complexion.
Jan. 28th. Took a powder, five grains of the third trituration
(decimal) of Cinnabaris at 11 o'clock p.m., about half an hour before
retiring. In ten minutes after, he felt a warm glow through his legs,
which was soon succeeded by a dull pain in the left arm just above the
elbow, and by occasional darting pains in the lower extremities. There
was also a dull pain in the lower dorsal portion of the spine, continuing
only for a short time. A space about the size of a quarter of a dollar,
just above and between the supra-orbital regions (root of nose ?), felt as
though pressed upon by a cold metallic body ; while within the cra-
nium, underneath, there seemed to be more warmth than usual. A dull
pain, felt before, in the temple and side of the forehead, disappeared.
Urgent desire to urinate.
Although intending to sit up and study longer, yet feeling wearied
in body and confused in mind, he soon retired. Upon lying down
there were rumblings in the abdomen and pains passing from the epi-
gastric to the pubic region. There was also some nausea and uneasi-
Provings of Cinnabaris. 233
nessin the stomach. Every little noise about the house troubled him,
as though it were something serious. Although accustomed to dream
much, yet he had more troublesome dreams than usual. He awoke
and started up several times without purpose ; once with a heavy pain,
in the fore-part of the head. Upon arising at 7 o'clock in the morning
he felt a little giddiness and pain in the forehead, with a sensation of
soreness in the eyeballs. These passed away soon after breakfast.
Before noon acidity of the stomach, general headache and heaviness of
the eyes came on, somewhat as usual, only much aggravated.
The prover took 3rd centes. trit. previously, and felt nearly the same
symptoms as those recorded above, but did not ascribe the effect to the
medicine. In one of his dreams, he saw a spider as large as an ox.
Fifth Proving ; Sixth Attenuation.
Dr. John H. Henry, aged 22. Light hair, healthy.
From the 6th dilution. (The prover has taken the medicine repeat-
edly, and alleges that he always has experienced the same symptoms.
We have noted them down bona fide as they were given to us, although
some have expressed a doubt about them, because they were so many
and so distinct. This prover is, however, unusually sensitive to the action
of all medicines, and we could not do more than express to all our
provers the awful responsibility they underwent in diverging even in
the slightest degree from the most accurate and truthful statements).
Pain in the region of casuality. A sensation of sticking over the
secretive region, which increases and becomes a numb-pain, extending
to the right temple (time and locality), with a feeling of warmth on
the right side. Disposition to sleep during the day. The pain extends
from one temple to the other across the os frontis from right to left
(time and locality), is mild in the forehead but violent in the organs of
locality and time both night and day and on rising in the morning.
Before going to bed there is a drawing pain in the head, extending
from the crown to the occiput, inclining to the right. Pain deep as if
in the centre of the head.
Pain from the right lachrymal duct around the eye to the temple.
Drawing sensation from the right inner canthus across the malar bone
to the ear. A sensation as if there were something in the eyes, lasting
three days. Feeling as if the eyelids were enlarged or puffed, as
if the muscles were too short, when looking up to the wall. Pain
from the inner canthus of the left eye across the eyebrows (organs of
size, color, order, calculation). Itching of the lids of both eyes.
Itching of the nose with bleeding, after blowing it. The blood is
very dark. The itching is caused by pimples at the right nostril.
Taste as of tobacco, coffee in the mouth. Pricking sensation in the
mouth and fauces. Small spot on the left side of the tongue, which
itches. Small sore on the roof of the mouth. Itching on the left side
of the face.
On turning the head, pain on the right side of the neck, below the
234 Cinndbaris.
sterno-cleido-mastoideus muscle. Pain in the back part of the neck,
•when the head is thrown back, extending to the occiput. The muscles
of the back part of neck seem as if contracted. General pain all over the
back down to the loins, worse after every dose of medicine, aggravated
on drawing a long breath.
Pain in the upper part of the left and right lung, an inward soreness
over the heart, extending along the left arm on taking a long breath.
Mucus which is thrown up, tastes like old tallow, mixed with coffee.
Pain under the lower point of the sternum extending to the left side
under the short ribs. Pain along the left arm, particularly in the
little finger, third finger, and thumb. On supinating the forearm, the
pain is worse at the elbow. It feels as if the " crazy bone " were
struck. The least twitch causes the elbow-joint and shoulder to crack.
Itching in the palm of the right hand. Pain in the little finger of the
right hand. Itching in the joint of right hand.
Pain in the kneejoint worse at noon, while walking. Drawing in all
the muscles of the lower extremities on the under surface. Sore feeling
of the ankle, attended with heat and itching over the whole leg.
Sore feeling extending from the small of the back around both sides
over the ossa ilii, worse on pressure.
Pain in the lower part of abdomen, attended with diarrhoea and also
flatulence after taking the first dose. (Colic from eating boiled
cabbage.)
Sensation as if there were a raw spot in the centre of the urethra,
which woke him up two nights in succession. (Pain in the molar teeth
of right side. Increase of urinary discharge. Dreams with much
talking during sleep, which is very restless. Lassitude, weariness.
Feeling as if an attack of typhoid fever were to come on. Irascibility.
Livid circles around both eyes.)
Jan. 19th to 27th. One hour after taking twenty pellets of the 6th
dilution. Rush of blood to the back part of the head, attended with
violent itching and heat extending to each ear, and behind the left ear
there came three hard lumps, one the size of a small shot, the other
that of a buckshot, and the last a size larger. On the same night he
felt a sharp pain in the region of the kidneys, as if some one had driven
a nail on each side of the vertebras. More profuse discharge of clear
water. Flow of mucus from the right nostril, lasting for three days.
Pain on the seventh rib of- each side in a spot as large as a quarter
of a dollar, more on the left side. Violent constipation lasting all the
time he took the medicine, and for a loug time after. Bleeding piles
for two days. Violent itching in the anus, worse at night in bed. A
whitish furred tongue in the morning.
Jan. 28th. Violent itching of the corona glandis, with a profuse
secretion of pus ; the itching was so violent as to cause him to rub it,
which only eased it for a short time, to return with tenfold violence.'
Two small red spots made their appearance on each side of the o-lans
secreting a large quantity of lardaceous matter. It had the appearance'
according to his opinion, of herpes preputialis.
Provings of Cinnaharis. 235
Profuse sweating between the thighs. Violent erections in the even-
ing. After finishing the medicine all desire for an embrace is lost,
which was not the case before he took the medicine.
_ AlHhe above symptoms except the perspiration were most violent at
night in bed; the perspiration about 12 o'clock in the day. He had
also a constant pain in the left arm joint, when turning and straitening
the arm and when writing. (Every evening hoarseness, with croup-like
cough. Right middle finger and palm of hand scurvy tetter exedens.)
Sixth Proving ; Sixth and Third Attenuations.
Dr. Albert Lindsay, dark hair, aged 28, uses no coffee, tea, spices,
nor any other stimulants.
Jan. 11th, 1851. Twenty pellets of Cinnaharis 6th on going to bed.
Great restlessness at night, continual dreaming and wakino\ He
would be scarcely lost in a drowse, before he would be dreaming.
Vivid dreams of studies and business, etc. Drawing, aching pains in
the thighs from the hipjoints nearly down to the condyles, aggravated
by moving and accompanied with great lameness experienced on getting
up and attempting to walk, getting better after walking a short
distance.
Jan. 12th and 13th. Symptoms of a cold in the head (?), with
lameness of the thighs, much mucus in lumps of a dirty yellow color
from the posterior nares, during the whole week.
Jan. 13th. Took hventy globules at bed-time. Had many dreams and
waked up often. (Increased dryness of throat and mouth, being
obliged to moisten and rinse the mouth every time he wakes up.)
Jan. 14th. Toole twenty globules of Cinnab. 6, at V o'clock a.m.
Shooting, aching pain on posterior side of right thigh from the hip-
joint to the middle of the os femoris, about 9 a.m., on straining at stool.
In the evening of the same day, took again thirty globules. Continual
restlessness, and dreams that a lump is in his throat and right ear.
Jan. 16th. At night twenty to thirty globules. In addition to the
restlessness and dreaming, woke up with a throbbing pain in the organ
of conscientiousness, extending to forehead, over the eye.
During the day and night of the 17th of January he was troubled
with aching pains in the thighs; soreness in the umbilical region,
obliging him to turn during the night as well as during the day of the
18th. A weak sensation in the left eye during the 18th.
Vivid dreams of the lectures, particularly the anatomical, during the
night of the 18th. He could not believe that he was not actually there.
Almost every morning after waking, a kind of dull pain (some morn-
ings more intense and sharper) in the forehead and top of the head,
worse when lying on the left side and back, going off wheu turning to
the right side and pressing the forehead into the pillow. As soon as
he turns to the left side or the back the pains return. On turning to
right side or getting up and washing, the pains disappear.
236 Cinnabar is.
(The prover had formerly some dulness of the head and sometimes
some pain on waking, especially after drinking milk the night before,
also some dryness and foul taste in mouth, but these symptoms were
far less decided than since he has been taking the medicine.) Violent
itching and pricking on the inner side of the knee-joint ever since he
has commenced to take the medicine, worse in the night and the
morning before getting up.
Jan. 21st. Violent itching on the inside of the thighs, knees and
legs, worse at the knees, especially at night.
Jan. 22nd. At bed-time took 5 gr. of 3d trit. Had several
dreams and awoke several times through the night.
On waking up in the morning had an aching pain in the whole of
the forehead and top of the head, aggravated by lying on the left side
and back, relieved by lying on the right side and pressing the forehead
with the pillow. A dull, heavy, and at times a sleepy feeling during
the day.
Jan. 24th. Restless sleep with many dreams, feels very tired in the
morning, aching across small of the back and in the limbs. A kind of
throbbing pain in the forehead on waking, going off on pressing the
head on the pillow.
Jan. 25th and 26th. Same pain in a diminished degree.
Jan. 27th. Symptoms of cold in the head — fulness of the head —
discharge of much mucus from the nostrils. Aching pain in the small
of the back and legs. Uncommon tiredness and weakness. Sensation
of emptiness in the stomach and very hungry two hours after eating
a hearty breakfast. Sore on the inside of the under lip towards
the left.
Jan. 28th. Severe aching and drawing pains in the back from the
region of the kidneys to the sacrum, and in the thighs and legs all last
night and to-day. Drawing up of the legs affords relief. He did not
wake up with headache in the morning, but about 9 o'clock a.m. a
kind of a sore pain commenced at the crown of the head and extended
as far front as the organ of veneration (at times there is a slight sensa-
tion of throbbing) ; it is very sensitive to touch, he cannot even touch the
hair without causing a sore pain. This pain continued all day.
"Weakness and sleepiness in the eyes about noon ; could scarcely keep
them open.
Jan. 29th.^ No pain this morning but the scalp is sensitive to touch.
Slight pains in back and legs, but much better than yesterday.
(The prover here remarks that when he was from thirteen to seven-
teen years of age he took large quantities of calomel, and was in con-
sequence for years afflicted with terrible drawing aching pains in the
legs, especially twelve or twenty hours before a storm. He was a
regular barometer. The pains he experienced from the effects of the
medicine were exactly like those he suffered years ago from calomel.
He was of course entirely ignorant, like all the others, of the nature of
the medicine he had undertaken to prove.)
Provings of Cinnabaris. 237
Seventh Proving ; Sixth Attenuation.
Dr. C. L. Merriman, aged 31, light hair, nervous sanguine tempe-
rament.
1851, Jan. 28th. Twenty pellets of the Oth dilation of Cinnab. 10
O'clock A.M.
In two hours felt a fulness and general pressure in the whole head
as after taking cold, with dull, aching pain in the region of benevolence
— better in the open air.
Great drowsiness and lassitude in the warm room. Occasional
shooting and prickling pain in the two middle fingers of left hand,
better by firm pressure upon the thumb. The above symptoms conti-
nued about eight hours.
Jan. 30th. Twenty pellets of 6th. Symptoms similar in kind, but
somewhat less in degree, and passed entirely away in about eight hours.
Eighth Proving ; Third and First Dec. Triturations.
Dr. J. L. Mulford, of good constitution, not predisposed to any
acute or chronic disease.
1851, Jan. 25th. Took 5 gr. of 3rd trit. (y 1 ^) of Cinnab. on going
to bed, but without producing the slightest effect.
Feb. 2nd. Took 5 gr. of 3rd ( T \) without any effect.
Feb. 3rd. Took 10 gr. of 1st ( r \) trit. Shooting pains in the
forehead with great heaviness. Shooting pains in the inner canthus of
the right eye with a burning and itching.
Hoarseness of the voice in the morning, going off in two or three
hours.
Shooting pains in the bowels at intervals during the day. Flashes
of heat, confined to the abdomen, with great flatulence.
All the above symptoms more in the forenoon and less in the after-
noon and evening.
Feb. 4th. Pain in the bowels before each evacuation, all the other
symptoms as detailed above in a less degree.
Ninth Proving; Third Dec. Trituration.
Dr. D. S. Pratt, aged 24, dark hair. (Has been subject to irrita-
tion in the throat, posterior nares, tonsils and fauces for three years,
considerable inflammation after taking the slightest cold, worse at
night, secretion of tenacious mucus during the day and dryness at night,
much soreness in the morning. Inclination to empty deglutition, fits
of violent sneezing ; has also derangement of the stomach, much flatus,
with disturbed sleep, &c, &c.)
The prover took 5 gr. of the 3rd trit. of Cinnab. ( T V) at three
different times, followed by much improvement in the throat.
The only symptom of an unusual character that he observed, was a
pressing pain in the right temple.
238 Cinnabar is.
Tenth Proving.
Dr. J. M. Randell, dark hair, dark complexion, aged 20.
1851, Jan. 13th. Twenty globules of the 6th dilution. Seems to
lower the pulse in the forenoon and make it irregular. Twenty min.
of 12 o'clock pain in the left side of the head, temple and supra-orbital
ridge. Sensation as if the abdomen were too large, and wishes to have
everything loose about the bowels.
Numb pressing pain in the eyes. Numb feeling in the elbows, as if
the ulnar nerve was compressed, also numbness in the knee-joints.
Hands cold. Pain in the forehead. Sticking in the chest just beneath
the sternum. Griping pain in the bowels. The pulse, which was at
12 o'clock m. from forty-four to fifty-two, rose at 4 o'clock to eighty.
Pain in the organ of tune. Sensation as if there were something in the
ear. In the afternoon his friends remarked that he was very cross and
sullen. Sleep restless with vivid dreams, but he cannot remember them
in the morning ; urine turbid. Pain in the tendo-achillis and os calcis
after walking. Pain in the left side of the face and teeth.
The above symptoms were produced by a single dose. Several other
doses had a similar effect.
Eleventh Proving ; Thirteenth Attenuation.
J. C. Raymond, aged 27.
1851, Feb. 3d, Monday evening. Twenty globules of the 30th dil.
of Cinnab.
In about an hour had sharp darting pains like electric flashes passing
from the first phalanx of the ring finger of the right hand to the middle
of the fore-arm and from the lower extremity of the radius of the left
arm up to the elbow.
Restlessness and sleeplessness during the night from a constant flow
of ideas, changing from one subject to another.
On Tuesday an increased flow of saliva. From four to five o'clock
p.m. a severe pain extending from the cartilage of the seventh rib at its
juncture with the sternum, to the right hypochondriac region under the
inferior border of the tenth rib.
On Tuesday night he took 40 globules ; on Wednesday night
took 60 globules ; on Thursday night took 5 gr. of 1-10, and on Friday
night 10 gr. of 1-10, with no perceptible effect until Saturday, when
there was increased sexual desire, with erections, which continued at
night, terminating by an emission of semen.
Feb. 9th. On Sunday night, took 20 pellets of the 30th attenuation.
An increased flow of saliva during the day on Monday, so much so,
that when he attempted to speak, he found some difficulty from his
mouth being constantly filled with saliva. He had some pain of a dull
character in the forehead, over the eyes in the afternoon, which became
severer in the evening, and was aggravated by motion. Had occasional
pains in the left side of the chest between the cartilages of the 5th and
6 th ribs.
Provings of Cinndbaris. 239
Tuesday. The increased flow of saliva still continues.
In the afternoon pain of a dull aching character, in the right frontal
region, aggravated in the evening. Also a return in the evening of the
pains in the left side of the chest, in the region of the heart, of a sharp cut-
ting character, producing difficulty in getting breath, while they continued.
Wednesday night he was awakened several times from sleep by a severe
pain in the right arm. It continued in the morning and during the day
of Thursday, at times very severe, commencing about the centre of the os
humeri and extending to the elbow, and along the radius to its inferior
extremity ; the pain was of a heavy aching character, deep-seated, and
caused lameness and difficulty in moving the arm. In the forenoon
he had also a return of the sharp cutting pains in the region of the
heart, followed by wandering pains throughout the whole chest.
Twelfth Proving.
Dr. Hamilton Ring. Aged 29, light hair.
1851. Jan. 14th. 20 pellets of 30th dilution of Cinnab. at 4 p.m.,
and on the 15th also, 20 pellets of the same dilution at 9 a. m.
In the course of the day (15th), he experienced on the bridge of the
nose, a sensation similar to that produced by touching it with a metallic
substance. Sticking pain about the punctum lachrymale of left upper
eyelid.
Next day, Jan. 16th, he noticed a small pimple (like a transparent
vesicle), sore to touch, on the inner edge of the eyelid, near the spot
where the pain was, which latter had disappeared.
Jan. 17th. 10£ a. m. Took 30 pellets of 6th dilution.
Soon after, aching and someivhat sharp pain in the left hypochon-
drium, in front, over a space as large as may be covered by the hand ;
worse on moving about and in the open air. Pain soon extending
around the lower border of ribs behind, and to region of left kidney,
where it seems dull and someivhat oppressive. (All felt and disap-
peared in four hours).
Soon after this appearing in right hypochondrium, in front, and
extending around to back, and region of right kidney, where the pain is
of the same character as in the left kidney.
The dull pressive pain is felt in one and then in the other region of
the kidney alternately.
The pains intermit in severity, and those in the hypochondria are
relieved by bending forward.
Occasional flashes of pain in right temple from in front backwards
(organ of mirthfulness).
Soreness in roof of the mouth.
Heaviness in head, desire to sleep during the day, restlessness at
night, indisposition to mental exertion.
The above symptoms appeared nearly, if not exactly, in the order in
which they are written ; those in italic were felt most severely
Jan. 18th. (In the evening, occasional shootings in upper part of
R
240 Cinnabar is.
left temple, along temporal ridge, dulness in the whole head, especially
in the forehead just over the eyes, lame sensation in right shoulder
joint.
Jan. 19th. At 10£ a. m., took one powder of l£ trituration
(centesimal), after which the following symptoms were experienced.
An hour after, an uneasy, creeping and pressive sensation about the
ossa nasi, lasting about an hour, and is the sensation experienced by
most persons on putting on a pair of heavy spectacles, if not accustomed
to wear them. Also for a short time a pain and sensation of fulness in
the meatus of the left ear.
In the evening a sensation of approaching looseness of the bowels.
Itching in various parts of the body, while walking in the open air.
Jan. 20th. In the forenoon head foil, nervousness and irritability
about noon, for a short time; also, for a short time, sticking pain in the
back part of left knee joint ; in the afternoon a slight pain in right
knee joint (similar to the pain in the left one), with a creeping sensation
above and below it, seemingly about the bone, lasting about an hour ;
(during the day itching over the body).
Jan. 21st. Frequently itching over the body, and itching and sticking
in the internal and external canthi ; head full, heavy, with strong pulsa-
tions of temporal arteries, great inclination to sleep during the day.
Jan. 2 2d. Itching on body and in the canthi, as before ; a spot
on right side, on one of the ribs (7th and 8th), as large as a wafer,
very sore to touch, with occasionally a sore pain in and around it, head
less heavy than the day before, a sore spot on the tip of the tongue.
Jan. 23d. About 4 A. m. was awaked by a dull sticking pain
in region of left kidney, which lasted but a short time. Afterwards
tossing about and sleeplessness for an hour ; after rising from bed, a
fulness and pressure in the occiput and back of the neck, continuing
with much severity until about noon ; after which the symptom some-
what abated ; heaviness and sleepiness during the day ; pains of short
duration in the right hypochondrium, in middle of left breast, in front
in tho left kidney, occiput ; itching over the body at times.
In the evening, sticking pain in the region of left side of 5th and 6th
dorsal vertebrae ; the sore spot on the right side has continued with the
characteristic symptoms before mentioned ; during the day there were
pains at a corresponding spot in the left side of the same character as
pains connected with the other, but without a sore spot.
Jan, 24th. Occasionally a sticking pain on the right side of the same
dorsal vertebras (5th or 6th) ; pain sometimes in the left side of occiput
(organ of amativeness) ; itching of eyelids, and of various parts of the
body; sore spot on the right side continues.
The pains in the knee-joint, mentioned as having been experienced on
the 20th inst. have been occasionally felt in a slight degree every day since.
The sore part on the right side continued 3 or 4 days.
The itching in various parts of the body and in the canthi of the
eyes were felt for 5 or 6 days.
The dulness of the head and unfitness for mental exercise have not,
after the lapse of a week, entirely disappeared.
Provings of Cinnabaris. 241
The severest pains experienced were those in the hypochondria and
kidneys.
The pains mentioned as felt on the 23d and 24th, on the side of the
5th or Gth dorsal vertebra?, were occasionally felt until the 27th.
Has been disposed to costiveness during the whole time of taking the
medicine.
On the 27th after dinner had a feeling of weight in the lower part of
the rectum and a sensation like aching.
Thirteenth Proving ; Fifth Attenuation.
Dr. C. E. Toothacher, of lymphatic nervous temperament, brown
hair, general health good. In childhood affected with rachitis. In
youth with burning sensation in chest, with colic in umbilicus and
stomach ; subsequently he had pains in the face, itching, burning in
throat and roof of the mouth. At present ringing, humming or roar-
ing in the ears, with frequent itching sensations over the whole body,
slight dull pain in the back of the head and neck, sense of dull pain in
one or both ears. Some remains of a former severe chronic bronchitis,
causing frequent hawking and spitting, with thick pus-like mucus in the
morning. Disposition to flatulence in the bowels ; passes water fre-
quently. Frequent sleepiness when sitting. Languor.
1851, Jan. 18th. 9 o'clock A. m. took 30 pellets of the 5th dilution of
Cinnabaris. 6 o'clock p. m. Sensation of soreness on the left side of
the root of the tongue on swallowing, accompanied by roughness and
stiffness, continuing through the night.
Jan. 19th. At 9 o'clock a. m. took 30 pellets more; at 10 o'clock,
slight pain in the sinciput. Sense of elevation on walking in the open
air ; never felt better in his life ; like the effects of a cordial. At 8
o'clock p. m., after tea, a peculiar metallic taste in the mouth, not much
unlike sulphate of zinc, or the taste left after a metal or salt, continuing
more or less one hour.
Jan. 20th. 5 o'clock next morning, a peculiar agreeable sensation of
exhilaration, and with fulness extending from all sides of the chest,
particularly the thorax, towards the stomach and heart, accompanied or
followed by a similar sensation in all the joints, continuing with intermis-
sions till 8 o'clock ; occasional pain in the sinciput. A peculiar drawing in
the mouth after rising, until breakfast. A small sore on the right side
of the tip of the tongue, also one on each lip, continuing several days.
At 2 o'clock p. m. sensation in the mouth and continued since 8
o'clock, modified by a continual tendency to hawk and spit, with unusually
copious flow of saliva and mucus, also a sensation of warmth under the
sternum, and sense as if secretions were flowing from the stomach and
all the mucous surfaces, as well as from the salivary glands.
A peculiar nervous thrill pervading the whole frame, even to the
fingers and toes, affecting especially the joints. Sense of languor and
depression, as after excessive exhilaration or intoxication. The above
sensation continued with intermission for 3 days.
24:2 Cinndbaris.
In the eyes for two days excessive itching in the inner canthi from
6 o'clock the first evening.
From 9 to 12 o'clock, itching in the outer canthi, severe and frequent,
with a sense of stiffness in the upper eyelids.
In the afternoon, when sitting in the house, a sensation as if a breeze
of cold air was blowing upon the eyes, very marked. Eyes very sensi-
tive to cold air in walking out.
Frequent pain in the lower side of the left knee near the inner side
of the tibia; lameness and frequent stitches on walking, particularly
inner side of knee-joint.
Fourteenth Proving; Sixth Attenuation.
Dr. Daniel Wilder, set. 39.
1851. Jan. 13th. 20 globules of Cinnabaris, 6th dil., on going to
bed. Restless, uneasy sleep.
Jan. 14th. 20 globules of 6th dil. on going to bed. Increased
restlessness, with constant dreaming ; seemed to dream before getting
asleep.
Jan. 15th. Pain in all the joints, with lameness during the day.
Dull pain in the forehead, which is cold and is relieved by the warm
hand — aching soreness of the eyes, worse in the evening. Pulse at
noon 60, in the evening|80. Aching soreness in the teeth. Regurgi-
tation of wind from the stomach ; sores in the mouth on the underlip —
severe pain in the forehead, which lasts all night ; great restlessness
and nervousness. A good deal of mucus at the posterior nares, which
comes away in lumps.
An eruption on the inner and lower part of the thigh, with itching.
Unusual irritability during the whole time since he took the medicine.
Fifteenth Proving.
Mr. John R t, aged 27, nervous, sanguine temperament.
1851. Jan. 14. Tuesday. Took 20 (/lobules of the 30th dil. be-
fore going to bed. Slept very well, but had very vivid dreams, which
he could not remember.
Next day, general nervous uneasy sensation — feels desirous of
improving spiritually, but is rather disconsolate.
Jan. 15th. Wednesday, 10 p. m. Took 20 globules of 30th dil.
Felt a drowsy sensation as though he could readily sleep — went to bed
at 1 2 o'clock. He still had the drowsy sensation and very strong desire
to sleep, but he could not_ sleep on account of a disagreeable, nervous
sensation, which caused him to toss about in bed for an hour and a half.
He sleeps not so well as the night before, and his dreams are vivid and
rather pleasing, but he cannot bring them to his recollection. (He
dreams more or less every night, but thinks his dreams were rather
unusually vivid.)
Jan. 16th. Thursday. _ His mind is in a morbid state, he is dis-
posed to fret at trifles, and is not at all satisfied with himself. At night
Provings of Cinndbaris. 243
the same day he took 40 globules of 30th dilution. He is again rest-
less and has vivid dreams.
Jan. 17th. Friday. A still more aggravated morbid state of the
mind, fretfulness. Also sexual excitement on the least provocation.
At_ 10 p. m. took 5 gr. of 3d trit. (centesimal). He felt no
desire for sleep, but sat up and read until half past one on Saturday
morning. He did not sleep for half an hour after going to bed. He
dreamed continually, but not so vividly as before.
On waking at 8 o'clock his throat is dry, he is thirsty, sensation as if
he had not had a refreshing sleep.
He has no particular sensations on Saturday. His moral and men-
tal state is rather improved.
At 2i p. m., sexual excitement as if he were to have an emission,
but is able to combat the feeling.
From the first time he took the medicine, he felt as if pimples were
to. come out over his body, with a general uneasy sensation and itching.
(The prover has had this feeling for some time, but now in an aggra-
vated form.)
Symptoms of flatulency of the stomach, irregularity of the passages,
pressing in the forehead, with a sensation of congestion, to which the
prover had been subject for some time, have now nearly disappeared.
Since taking the medicine it is quite difficult for him to fix his mind
long on any subject. He cannot pay attention to the lectures as well as
before. This sensation is relieved by the open air. He cannot think long,
deeply or clearly on any subject, and his mind seems to be altogether
disturbed.
Jan. 19th. Sunday, 12 m., took 5 gr. of 3d decim. trit. 5 p. m.,
strange congestive sensation about the head, principally in the forehead.
8 J to 10j p. M., fulness and pressure in the forehead.
10^ p. m. sensation of water in the left ear, which soon passes off.
Pain and tired feeling in the right hip and afterwards in the left. Tired
feeling in all the joints of the lower extremities, better from rising and
walking ; sensation of having taken cold, and general feeling as not
being fit for any mental labor ; depressed, melancholy, cynical state of
mind, nervous system excited.
Jan. 21. Tuesday, 8 a. m., took 40 globules of 6tk dilution. No
symptoms observed until 7 p. m . Left cheek flushed, and in left eye
watery sensation ; soon passed off; congested sensation over the whole
head, particularly in the forehead; great difficulty of collecting ideas
and studying usefully, and even aversion to close study ; after retiring
did not sleep for over an hour, but tossed about, very nervous and men-
tally vexed.
Jan. 2 2d. Wednesday. Symptoms of mind and head much the
same as Tuesday evening. Eruption on posterior cervical region and
soreness from right ear into the middle of the posterior cervical region,
as if the glands were affected.
Jan. 23d. Thursday. Increase of the soreness, very severe in the
evening. The left eye still continues to water several times, passing off
each time in a few minutes.
244 Clnncibaris.
The soreness in the posterior cervical glands continues until Jan. 27th,
but it gradually decreased in severity. Has also occasionally fever and
fulness in the forehead. Itching at night, especially on the inside of
the thighs.
Sixteenth Proving.
T. took 20 globules of 30th dil. Cinnab. at night. Had an increase
of the flow of saliva, and a pain running near the ensiform cartilage
from the 7th rib on the right side diagonally through to the chest.
No farther effect was produced from 40 to 60 glob, of same dil., nor
from 5 gr. and 10 gr. of the 1st decimal trit.
Seventeenth Proving.
Mrs. H. took the 6th dil. and experienced a great increase of the
flow of urine and saliva, lasting one hour ; with shooting pain in the
left side of the head from the occiput to forehead — flow of tears.
Eighteenth Proving.
Miss F. took one dose of Cinnab. 6th, and had a dizziness and light-
ness of the head — soreness in the stomach, with tightness in the
temples.
Nineteenth Proving.
Mrs. F. took at 8 a. m. 20 drops of the 5th dil. of Cinnab. At
half past 8 A. m. sensation of fulness and weight across the temples,
with sometimes throbbing over right temple, worse on motion. These
symptoms disappeared before noon. Aching in small of the back, as if
bruised.
* There are days in the evenings of which, she feels unusually well
and strong.
Feb. 5th. Took at 8 a. m. 10 drops, of 5th dil. Aching in both
ears, lasting about fifteen minutes. At 11 o'clock unusual drowsiness
and heaviness over the eyes. (In the evening nervous trembling of the
heart with anxiety, to which she had formerly been subject, again
returns.)
From 1 gr. of 5th decimal trit., unusual drowsiness in the morning.
In the afternoon, two passages of the bowels, the last one with straining.
* Mind clearer and more cheerful.
Unusually vivid dreams of a sensual nature.
Twentieth Proving.
< A patient of light complexion who received Cinnabaris, 1st tritura-
tion, for a phimosis, soon complained of the following most obstinate
symptoms, which he never felt before, and which may be clearly ascribed
to the effect of the medicine.
He took it for two weeks with constant improvement to phimosis.
After discontinuing it for ten days he still had the severe pain in the
Digest of the Symptoms. 245
head, which was mitigated by Sulph. and Bellad., but only finally
relieved by Iodine. Nitric Acid aggravated it.
Intense headache, relieved by external pressure. This pain was so
severe that he could hardly endure it. Noises in the ears after eating.
Head excessively sore on the outside to every touch. Pain darting
through from the sides of the head and the temples. The pain is near
the outer edge of the orbit of the right eye, and more frequent on the
right side of the head than the left. Constant pain in the right side of
the head. From the temples the pain goes to the occiput. Excessive
lachrymation.
Dryness in the mouth, with desire for cold water. Bad taste in the
mouth, with phlegm and ptyalism ; loss of appetite ; eats very little ;
constipation, only one passage in a week ; soreness under the right
breast near the last true rib, particularly on drawing breath. Feeling
of coldness and sensation of inertia; drowsiness; nightly sleeplessness;
hears the clock strike every hour ; redness of the skin, like a chronic
eruption. He wakes up suddenly as from a dream. The headache is
much worse after sleeping.
4. Digest of the Symptoms.
The following are the abbreviations used : —
1. S. A.— Dr. S. Armor.
2. B. — Some women and girls proving under the direction of a
friend of Dr. Hering's (3d trituration).
3. A. J. B.— A. J. Brewster.
4. J. P. D— Dr. J. P. Dake.
5. H. — Hahnemann.
6. C. Hg.— Dr. C. Hering.
7. J. H. H.— Dr. J. H. Henry.
8. Ktz. — from Koschwitz's translation of " Schroeder's Arznei-
schatz"
9. L. — Dr. A. Lippe.
10. A. L. — Dr. Albert Lindsay.
11. C. L. M.— Dr. C. L. Merriman.
12. J. L. M.— Dr. J. L. Mulford.
13. Nd. — Dr. C. Neidhard, including symptoms from three ladies,
and from a patient of Dr. N.'s.
14. D. S. P.— Dr. D. S. Pratt.
15. J.M.R.— Dr. J. M. Randell.
10. J. C. R.— Dr. J. C. Raymond.
17. H. R.— Dr. Hamilton Ring.
1 8. Rt. — a prover who does not permit the use of his name.
19. C. E. T.— Dr. C. E. Toothacher.
20. D. W.— Dr. Daniel Wilder.
The asterisk (*) is prefixed to curative symptoms.
Antidotes. — Sulph. and Bellad. mitigated the severe pain in head,
but Iodine finally cured it. Nitric-acid aggravated it. (Nd. 1st.)
246 CinnabaHs.
Moral Symptoms and Head.
(1.) Indisposition for mental labor. The head feels heavy as from
long mental application ; a dull heavy ache in the front of the head to
the occiput, mostly over the right eye and temple, with heat ; occasional
darting pains through the head from without inwardly. (A. J. B.,
6th ail.)
Although intending to sit up and study longer, yet he felt so wearied
in body, and confused in mind, that he soon retired. Upon lying
down there were rumblings in the abdomen, and pains from the
epigastric to the pubic region. There was also some nausea and
uneasiness in the stomach. Every little noise about the house troubled
him, as though it were something serious. Although accustomed to
dream much, yet he had more troublesome dreams than usual. He
awoke and started up several times without purpose : once with a heavy
pain in the forepart of the head. Upon rising at 7 o'clock in the
morning he felt a little giddiness and pain in the forehead, with a sensa-
tion of soreness in the eye-balls. These passed away soon after breakfast.
Before noon acidity of the stomach, general headache, and heaviness
of the eyes came on, somewhat as usual, but only much aggravated
(J. P. D., 5 gr., 3d trit.)f
Heaviness in the head, desire to sleep during the day, restlessness
at night, indisposition to mental exertion (H. R., 6th dil.)
The dulness of the head and unfitness for mental exercise have
not, after the lapse of a week, entirely disappeared (H. R., 6th).
Since taking the medicine it is quite difficult for him to fix his
mind long on any subject. He cannot pay attention to the lectures so
well as before. This sensation is relieved by the open air. He cannot
think long, deeply and clearly on any subject, and his mind seems to
be altogether disturbed (Rt., from 5 gr. of 3d cent, trit.)
Left cheek flushed, and left eye watery, sensation which soon passed
off. Congested sensation over the whole head, particularly in the
forehead; great difficulty of collecting his ideas and studying usefully,
and even aversion to close study. After retiring did not sleep for over
an hour, but tossed about very nervous, and mentally vexed (Rt., 40
glob., 6th dil.)
The above symptoms of mind and head continued the same the
next day (Rt.)
Sensation of having taken cold, and a general feeling as not being
fit for any mental labor ; depressed, melancholy, cynical state of mind ;
nervous system excited (Rt., 3d.)
Restlessness and sleeplessness during the night from a constant flow
of ideas changing from one subject to another (1st day. J. C. R. 30th.)
+ (These and similar groups I have thought best not to separate, as they
disclose the consecutive action of the remedy in different parts of the body,,
forming true medicinal diseases. I did this at the risk of many repetitions
at subsequent divisions.)
Digest of the Symptoms. 247
Forgetfulness of things which, he has to do, and which, under
other circumstances, he would not easily forget — as, neglecting to
extinguish the light.
Forgets to notice the symptoms (C. Hg., 1st day, 3d trit.)
Inattention to the symptoms (C. Hg.)
Fretful and inclined to weep ; he reproaches others (B.)
* Mind clearer and more cheerful (5th, Nd.)
His mind is in a morbid state ; he is disposed to fret at trifles,
and is not at all satisfied with himself (1st day, 30th, Rt.)
Next day a still more aggravated morbid state of mind ; fretfulness ;
also sexual excitement on the least provocation (Rt. 30th.)
Great depression of spirits after meals (B.)
Pain in the organ of tune ; sensation as if there was something in
the ear. In the afternoon his friends remarked to him that he was
very cross and sullen (1st day. J. W. R., 6th dil.)
Irascibility (J. H. H., 6th J.
Involuntary thoughts and imaginations without occasion ; fear of his
or others falling, etc. (C. Hg.)
* Mistakes of the imagination (Ktz.)
Yawning ; not inclined to speak, and an intolerable feeling when
spoken to (3d trit. L.)
Desire to be alone (3d, L.)
Giddiness, particularly on stooping (B.)
Vertigo and lassitude, particularly in the morning after rising (B.)
Giddiness, with nausea ; pressing pain in the forehead disappearing
after lying down and during sleep (B.)
Upon rising at 1 o'clock in the morning, he felt a little giddiness and
pain in the forehead, with a sensation of soreness in the eyeballs. These
passed away soon after breakfast (J. P. D. 3d, 1st day).
Dizziness in the head in the morning after rising (2d day, B.)
Dizziness and lightness in the head ; soreness in the stomach, with
tightness in the temples (Nd., 6th dil.)
Roaring in the head, half an hour after dinner, and in the evening
before retiring, causing dizziness (H.)
Fulness and determination of Hood to the head.
Fulness of the head very frequently (1st, 3d day, C. He;.).
Fulness of the head and eyes, eyes reddened (C. Hg., 3d trit).
Fulness in the head and about the eyes, which are red (3d L.).
In the evening occasional shootings in the upper part of left temple,
along the temporal ridge ; dulness in the whole head, especially the
forehead, just over the eyes; lame sensation in right shoulder joint
(2d day, H. R., 30th).
Unusual drowsiness and heaviness over the eyes (Nd. 5th, 1st day).
In the forenoon, head full ; nervousness and irritability about noon
for a short time ; also, for a short time, sticking pain in the back part
of left knee joint ; in the afternoon, sticking pain in the right knee
248 Cinnabaris.
joint, with a creeping sensation above and below it, seemingly about
the bone, lasting about an hour (H. R. !■$■ trit, 2d day).
Frequently itching over the body and itching and sticking in the
internal and external canthi ; head full, heavy, with strong pulsations
of the temporal arteries ; great inclination to sleep during the day
(H. R., U trit., 3d day).
Head less heavy the fourth day (H. R., 1^- trit.)
Symptoms of cold in the head ; fulness of the head, discharge of
much mucus from the nostrils ; aching pain in the small of the back
and in the legs. Uncommon tiredness and weakness. Sensation of
emptiness in the stomach, and very hungry within two hours after eat-
ing a hearty breakfast ; sore on the inside of the under lip towards the
left (Gth day, A. L.).
Symptoms of cold in the head, with lameness of the thighs ; much
mucus in lumps of a dirty yellow color from the posterior nares during
the whole week (A. L., 6th).
Fulness and pressure in the forehead in the evening (Rt., 30th).
Occasionally, fever and fulness in the forehead (Rt., 6th).
* Symptoms of flatulency of the stomach, irregularity of the pas-
sages, pressing in the forehead, with a sensation of congestion to which
the prover had been subject for some time, have now disappeared (Rt.,
30th dil., and 3d trit.)
. Determination of blood to the head the whole day (12th day, C. Hg.)
Flatulence after congestion to the head in the forenoon, during the
first day (C. Hg.)
Left cheek flushed and left eye watery sensation, which soon passed
off. Congested sensation over the whole head, particularly in the fore-
head ; great difficulty of collecting his ideas and studying usefully, and
even aversion to close study. After retiring, did not sleep for over an
hour, but tossed about, very nervous and mentally vexed (Rt., Gth.)
At 5 p. m., strange congestive sensation about the head, principally
in the forehead, after taking 5 gr. of 3d trit., at 12 M. (Rt.)
The determination of blood to the head, particularly to the vertex, is
aggravated when eating, so as to interrupt his meal (C. Hg.)
At 10 o'clock in the forenoon, when rising from the stooping posture,
so violent determination of blood to the head and neck, accompanied by
dizziness, as nearly to deprive him of his senses (1st day, C. Hg.)
Rush of blood to the back part of the head, attended with violent
itching and heat, extending to each ear, and behind the left ear there
came three hard lumps, one of the size of a small shot, the other that
of a buck-shot, and the last a size larger ; on the same night he felt a
sharp pain in the region of the kidneys, as if some one had driven a
nail on each side of the vertebra. A more profuse discharge of clear
urine. Flow of mucus from the nostril, lasting for three days (one
hour after taking 20 pellets 6th dil. J. H. H.)
■ t *A great number of persons have been relieved by Cinnabaris, of
congestion of blood to the head (Nd.)
In two hours after taking the medicine, he felt a fulness and general
Digest of the Symptoms. 249
pressure in the whole head, as after taking cold, with dull aching pain
in the region of benevolence ; better in the open air (C. L. M., 6th).
Intense headache, relieved by external pressure. This pain was so
severe that he could hardly endure it. The pain in the head is so
severe that he can scarcely raise his head from the pillow. It lasts from
\ past 12 to 6 p. m. (1st Nd.)
The headache is much worse after sleeping (1st Nd.)
Dull feeling in the head and pressing headache ; ameliorated in the
open air ; disappearance of the pain after bleeding of the nose ; after
bleeding ceases, general uncomfortable feeling (in 8 days, B.)
(He had formerly some dulness of the head, and sometimes a pain on
waking, especially after drinking milk the night before ; also some dry-
ness and foul taste in the mouth, but these symptoms were far less
decided since he has been taking the medicine.) (A. L., 6th.)
Pressing headache, occasionally a digging and gnawing in small
spots, for the most part in the upper and left side of the head
(300, C. Hg.)
Forehead, pains over the eyes, and concomitant symptoms.
Occasional pains in the sinciput (C. E. F., 5th, 2d day.)
A sharp steady pain in the forehead, mostly in the right orbital
region ; soon after, felt a sharp throbbing in the left hypochondrium in
the region of the spleen, after four hours. A dull aching pain in the
bones of the forearms and legs, in 11 hours (A. J. B., 3d.)
In half an hour, a sharp aching pain in the right supraorbital region,
shooting backwards and downwards to the ear and side of the neck.
Front of the head very hot. The pain in the head is worse in the warm
room, and on moving the eyes and scalp.
In eleven hours, at 10 p. m., the same pain is increased to a heavy
stupefying ache, aggravated by thinking, reading and pressure. Ten-
derness in the epigastric region.
In the morning better, but in the evening the pains in the head return
again, with a numbness and heavy aching in the arms and knees, and
lower legs, without another dose.
The same pains in the head return also in the morning at 11 o'clock,
with a disposition to fall asleep while trying to listen to the lecture, not-
withstanding his making a great effort to keep awake ; constrictive feel-
ing in the umbilical region, urine tinged yellow. Pains all aggravated
in the evening. Better in the open air, and after eating and sleeping
(A. J. B., 3d).
In the morning a sense of general prostration, great weakness of all
the limbs. Feeling of depression and weakness of the whole system,
as after a severe illness. Indisposition for mental labor. The head
feels weary as from long mental application.
A dull heavy ache in the front of the head, from before backwards,
mostly over the right eye and temple, with heat in the head. Occa-
250 Cinnabaris.
sional darting pains through, the head from without inwardly (A. J. B.,
6th, 1st day).
Pain in all the joints with lameness during the day. Dull pain in
the forehead, which is cold, and is relieved by the warm hand. Aching
soreness of the eyes, worse in the evening (D. W., 6th, 2d day).
During the first day, he experienced on the bridge of the nose a sen-
sation similar to that produced by touching it with a metallic substance.
Sticking pains about the punctum lachrymale of the left upper eyelid
(H. R., 30th).
A space about the size of a quarter dollar just above and between
the supra-orbital ridges (root of nose ?) felt as if pressed upon by a cold
metallic body, while within the cranium underneath, there seemed to
be more warmth than usual (J. P. D.).
*A dull pain, felt before in the left temple and side of the forehead,
disappeared (J. P. D., 3d).
An hour after taking the medicine, an uneasy, creeping, and pressive
sensation about the ossa nasi, lasting about an hour, and is the sensation
experienced by most persons on putting on a pair of heavy spectacles, if
not accustomed to wear them. Also for a short time a pain and sensa-
tion of fulness in the meatus of the ear. In the evening, a sensation
of approaching looseness in the bowels (H. R., 1^ trit.).
Pain in the forehead (region of causality). A sensation of sticking
over secretive region, which increases and becomes a numb pain, extend-
ing to the right temple (time and locality), with a feeling of warmth on
the right side. Disposition to sleep during the day. The pain extends-
from one temple to the other across the os frontis from right to left, is
mild in the forehead, but violent in the organs of locality and time, both
night and day, and on rising in the morning. Before going to bed
there is a drawing pain in the head, extending from the crown to the
occiput, inclining to the right. Pain deep-seated, as if in the centre of
the head (I. H. H., 6th).
Almost every morning after waking, a kind of dull pain (some morn-
ings more intense and sharper) in the forehead and top of the head,
worse when lying on the left side and back, going off when turning to
the right side and pressing the forehead with the pillows. As soon as
he turns to the left side or back, the pains return. On turning to the
right side, or getting up, or washing, the pains disappear (A. L., 6th).
On waking up in the morning had an aching pain in the whole of
the forehead and top of the head ; aggravated by lying on the left
side and back ; relieved by lying on the right side and pressing the
forehead with the pillows. A dull, heavy, and at times a sleepy feeling
during the day (W. L., 3d., 1st day).
Although accustomed to dream much, yet he had more troublesome
dreams than usual. He awoke and started up several times without
purpose ; once with a heavy pain in the forehead. Upon arising in the
morning he felt a little giddiness and pain in the forehead, with a sensation
of soreness in the eye-balls. These passed away soon after breakfast.
Before noon, acidity of the stomach, general headache, and heaviness
Digest of the Symptoms. 251
in the eyes, came on, somewhat as usual, only much aggravated.
(J. P. D, 3d). y S *
Pain in the forehead ; sticking in the chest just beneath the sternum ;
griping pain in the bowels (J. M. R, 6th).
After taking the medicine the night before, he had an increased
flow of saliva the next day, so much so, that when he attempted to
speak he found some difficulty, from his mouth being filled with saliva.
He had some pains of a dull character in the forehead over the eyes in
the afternoon, which became more severe in the evening, and was
aggravated by motion. Had occasional pains in the left side of the
chest, between the cartilages of the 5th and 6th ribs.
The second day the flow of saliva still continued ;' in the afternoon he
had again a dull aching pain in the right forehead, aggravated in the
evening ; also a return of the pains in the left side of the chest in the
region of the heart of a sharp, cutting character, producing a difficulty
of breathing (J. C. R., 30th).
Dull pain in the forehead, which is cold, and relieved by the warm
hand ; aching soreness of the eyes, worse in the evening ; pulse
rises from 60 to 80 in the evening ; aching soreness in the teeth.
Eructations of wind from the stomach ; sores on the mouth on the
under lip. Severe pain in the forehead, which lasts all night ; great
restlessness and nervousness ; a good deal of mucus at the posterior
nares, which comes away in lumps (D. W., 6th).
Dull pain in the forehead the entire day (B., 9th day).
Pressing pain in the forehead, which spreads upwards, seems to be
between the external skin and the muscle ; it is aggravated by lying
and pressing upon the pillow (B.)
Pain in the right side of the forehead, then in the left, where it is
more violent, and draws downwards to the chest; it again recurs
somewhat later, diminished by exercise and perspiration (B.)
Pressing in the forehead at five o'clock in the morning, before rising,
with dizziness and nausea ; disappears after rising and eructations of
wind (B.)
Throbbing in the forehead at noon (3d day, B.)
Pricking pain in the forehead during the whole night (B.)
Shooting pains in the forehead, with great heaviness.
Shooting pains in the inner canthus of the right eye, with a burning
and itching.
Hoarseness of the voice in the morning, passing off in two or three
hours.
Shooting pains in the bowels at intervals during the day. Flushes
of heat confined to the abdomen, with great flatulence : all the above
symptoms more in the forenoon, and less in the afternoon and evening
(J. L. M., 1st).
252 Cinnabaris.
Temples and sides of head.
Pain from the right lachrymal duct around the eye to the temple.
Drawing from the right inner canthus across the malar bone to the ear
(J. H. H., 6th).
Dulness in the head, mostly on the right side and towards the posterior
part, and about the right ear, in the forenoon after some hours (C. Hg.)
Sensation of fulness and weight across the temples, with sometimes
throbbing over right temple, worse on motion (for half an hour, Nd., 5th).
Occasional flashes of pain in right temple, from in front backwards
(organ of mirthfulness), soreness in roof of mouth. Heaviness in head,
desire to sleep during the day, restlessness at night, indisposition to
mental exertion (H. R, 6th, 1st day).
Pain darting through from the sides of the head and the temples.
The pain is near the edge of the outer orbit of the right eye, and more
frequent on the right side of the head than the left. Constant pain in
the right side of the head. From the temples the pain goes to the
occiput (Nd. 1st).
A sensation of sticking over secretive region, which increases and
becomes a numb pain, extending to the right temple, with a feeling of
warmth on the right side (J. H. H., 6th).
Pressing pain in the right temple (D. S. P., 3d).
Pain in the left side of the head, temple and supra orbital ridge.
Sensation as if the abdomen was too large, and wishes to have every-
thing loose about the bowels. Numb pressing pains in the eyes. Numb
feeling in the elbows, as if the ulnar nerve was compressed ; also numb-
ness in the knee joints. Hands cold (J. M. R., 6th).
In the evening occasional shootings in upper part of left temple, along
temporal ridge ; dulness in the whole head, especially in the forehead
just over the eyes ; lame sensation in the right shoulder joint (H. R.,
6th, 2d day).
Dizziness and lightness of the head ; soreness of the stomach, with
tightness of the temples (Nd., 6th).
Frequently itching over the body and itching and sticking in the inter-
nal and external canthi, head full, heavy, with strong pulsations of tem-
poral arteries, great inclination to sleep during the day (H. R., 14-, 3d day).
Three or four hours after taking the 3d decimal trit. of Cinnab. in
the morning, his abdomen, below the transverse colon, felt hot, his
tongue is covered with a white fur and there is a beating and burning
in both temples, which he felt all day (S. A.)
Occiput and crown of 7iead.
An hour after taking the medicine in the morning, he has a violent
pressing pain in the occiput, also in the left side of the head for two
hours. In the afternoon she was obliged to lie down and sleep, after
which the pain disappeared (B.)
A great increase of the flow of urine and saliva, lasting one hour,
Digest of the Symptoms. 253
with shooting pain on the left side of the head from the occiput to the
forehead ; flow of tears (Nd., Gth).
On turning the head, pain on the right side of the neck, below the
sterno-cleido-mastoideus muscle. Pain in the back part of the-
neck, when the head is thrown back, extending to the occiput. The
muscles in back part of the neck seem as if contracted. General pain all
over the back down to the loins, worse after every dose of the medicine,
aggravated on drawing a long breath (J. H. H., 6th).
Before going to bed, there is a drawing pain in the head, extending
from the crown to the occiput, inclining to the right. Pain deep as in
the centre of the head (J. H. H., 6th).
In addition to the restlessness and dreaming, he woke up with a
throbbing pain in the organ of conscientiousness, extending to the fore-
head over the eye (the night after taking 6th, A. L.)
About 4 A. m., was awaked by a dull sticking pain in the region
of the left kidney, which lasted but a short time ; afterwards tossing
about and sleeplessness for an hour ; after rising from bed, a fulness
and pressure in the occiput and back of the neck, continuing with much
severity till about noon, after which the symptoms somewhat abated ;
heaviness and sleepiness during the day; pains -of short duration m
the right hypochondrium, in middle of the left breast, in front in the left
kidney and in the occiput ; itching over the body at times. In the
evening, sticking pain in the region of the left side of the fifth and sixth
dorsal vertebras ; a sore spot on the right side seventh and eighth ribs,
which he had felt before, continues. It is very sore to touch, with occasion-
ally a sore spot in and around it ; during the day there were pains at a
corresponding spot on the left side of the same character as the pains
connected with the other, but without a sore spot (H. R., l£, 5th day).
The next day, occasionally a sticking pain in the right side of the
same dorsal vertebras (5th and 6th) ; pain sometimes in the left side of
occiput (organ of amativeness) ; itching of the eyelids and of various
parts of the body ; sore spot in the right side continues for three or four
days (H. R., l£, 6th day).
Eruption on the posterior cervical region and soreness from right ear
into the middle of the posterior cervical region as if the glands were
affected, which continues for seven days, but it gradually decreases in
severity (Rt, 6th).
Scalp.
About 9 o'clock in the morning a sore pain, commencing at the crown
of the head and extending as far as the organ of veneration (at time3
a slight sensation of throbbing), it is very sensitive to the touch — he
cannot even touch the hair, without causing a sore pain (the sixth and
seventh day). Weakness and sleepiness in the eyes about noon, could
scarcely keep them open (6th day, 3d, A. L.)
Sensitiveness of the head to the touch ; even the hairs are sore (H.).
Pricking about the exterior part of the head, only during the day (H.).
Head excessively sore on the outside to every touch (1st, Nd.).
* Has cured thousands as " specificum cephalicum" (Ktz.).
254 Cinndbaris.
Eyes.
Shooting pains in the inner canthus of the right eye, with a burning
and itching (J. L. M., 1st).
Head excessively sore on the scalp to every touch ; pain darting
through from the sides of the head and temples. The pain is near the
outer edge of the orbit of the right eye, and more frequent on the
right side of the head than the left. Constant pain in right side of
bead. From the temples the pain goes to the occiput; excessive
lachrymation (Nd. 1st trit.).
(Inflammation of the right eye ; itching, pressing, and pricking at
•the inner angle and the lower lid ; constant lachrymation on looking
steadily, with profuse discharge of mucus from the nose.) (H.)
Pain from the right lachrymal duct around the eye to the temple.
Drawing sensation from the right inner canthus across the malar bone to
the ear. A sensation as if there were something in the eyes, lasting
three days ; feeling as if the eyelids were enlarged or puffed, as if
the muscles were too short, when looking up the Avail. Pain from the
inner canthus of the left eye across the eye-brows (organs of size, color,
order, calculation). Itching of the lids of both eyes (J. H. H., 6th).
Redness of the corners of the eyes, mostly at the inner angles ;
right eye more affected than the left ; cornea appears encircled by a
red ring. All these symptoms are aggravated in the evening during
the first day (B.)
Eyes watery and dull, with a sharp sticking pain in the inner
canthus of the left eye, as of a sharp stick being stuck in the lower
lid (A. J. B., 6th ; 2d day).
Pain in the inner canthus of the left eye, with redness and
swelling, mostly towards the lower lid (C. Hg.).
Left eye watery sensation occasionally, for three days, passing off
each time in a few minutes (Rt., 6th).
Flow of tears (Nd., 6 th).
Sticking pain about the punctum lachrymale of the upper eyelid.
A small pimple (like a transparent vesicle) sore to touch, on the
inner edge of the eyelid near the spot where the pain was, which
latter had disappeared (H. R., 2d day).
Itching of eyelids and various parts of body (H. R., 1st).
Frequently itching over the body, and itching and sticking in the
internal and external canthi ; felt for eight days (H. R., 1st).
In the eyes for two days excessive itching in the inner canthi, from
six o'clock the first evening.
From nine to twelve o'clock ; frequent and severe itching in the
outer canthi, with a sense of stiffness in the upper eyelids. In the
afternoon when sitting in the house, a sensation as if a breeze of cold
air was blowing upon the eyes ; very marked. Eyes very sensitive to
cold air in walking out (C. E. F., 5th).
Redness of the inner angle of the eyes during the 5th day (B.)'
Redness of the whole eye, with swelling of the face (3 L.)<
Livid circles around both eyes (J. H. H., 6th).
Digest of the Symptoms. 255
Weakness of the eyes, with redness of the corners ; burning pain
(3d day, B.)
A weak sensation in the left eye during the 18th (A. L., 6th, 2d day).
About nine o'clock in the morning a kind of sore pain, commencing
at the crown of the head, and extending as far front as the organ of
veneration ; it is very sensitive to touch ; he cannot even touch the
hair, without causing a sore pain. This pain continued all day ; weak-
ness and sleepiness in the eyes about noon ; could scarcely keep them
open (A. L., 6th day ; 3d).
Eyes weak and over-clouded (5th day, B.).
Aching soreness of the eyes, worse in the evening (D. W., 2d
day; 5th).
Upon rising in the morning he felt a little giddiness and pain in
the forehead, with a sensation of soreness in the eye-balls. Before
noon acidity of stomach; general headache and heaviness of the eyes
(J. P. D., 3d).
Numb pressing pain in the eyes (J. M. R, 6th).
Fulness of the head and eyes; eyes reddened (C. Hg., 3d).
Ears.
Pressing, forcing pain deep in the right ear, inwardly towards the
neck after sitting down ; disappears while sitting, with dizziness after
two hours in the forenoon (C. Hg.).
Continued restlessness, and dreams a lump is in his throat and
right ear (A. L., 6th).
In half an hour felt a sharp aching pain in the right supra-orbital
region, shooting backwards and downwards to the ear and side of the
neck ; front of head very hot ; the pain is worse in a warm room, and
on moving the eyes and scalp (A.J. B., 3d).
Drawing sensation from the right inner canthus across the malar
bone to the ear (J. H. H., 6th).
Much itching in the right ear, and after using the ear-pick a pain
deep in the ear the 9th day (C. Hg.).
The right external ear becomes numb whilst sitting in the carriage
the 4th day (C. Hg.).
Rush of blood to the back part of the head, attended with violent
itching and heat extending to each ear, and behind the left ear there
came three hard lumps, one the size of a small shot, the other that of
a buckshot, and the last a size larger (J. H. H., 6th).
For a short time a pain and sensation of fulness in the meatus of
the left ear (H. R. ; 1st day, \\ trit.).
At 10 p.m., sensation of water in the left ear, which soon passes off
(Rt., 3d ; 1st day).
Much itching in the left ear from the 1st to the 4th day ; scurfy
eruption in the right external ear, between the helix and anti-helix,
the 4th day (C. Hg.).
Aching in both ears, lasting about fifteen minutes (Nd., 5th).
B
256 Cinnabaris.
Noises in the ears after eating (Nd., 1st).
Roaring in the ears, with swelling of the face (3d, L.).
Face and JVose.
Great heat in the face (while triturating the medicine from 11 to
12 o'clock a. m.), which is much swollen, mostly about the eyes
(3d, L.).
Heat and swelling of the face ; afterwards pain in the back part of
the head (3d, L.).
In the evening left cheek flushed ; left eye, watery sensation, which
soon passed off (Rt., 1st day, 6th).
Itching on the left side of the face (J. H. H , 6th).
Pain in the left side of the face and teeth (J. M. R.; 6th).
Tickling in the nose, obliging her to pick it with the fingers, after
the 8th day (B.).
(Violent pricking, jerking in the nose, particularly when eating
during the 1st day.) (C. Hg.).
(Sore in the nose in both nostrils at the point until fall, and also in
the spring, 1848) (C. Hg).
Itching of the nose, with bleeding, after blowing it. The blood is
very dark. The itching is caused by pimples at the right nostril
(J. H. H , 6th).
Symptoms of a cold in the head, with lameness of the thighs ; much
mucus, in lumps of a dirty yellow color, in the posterior nares during
the whole week (A. L., 6th).
Symptoms of cold in the head ; fulness of the head ; discharge of
much mucus from the nostrils ; aching pain in the small of the
back and legs (A. L., 3d, 5th day).
A good deal of mucus at the posterior nares, which comes away in
lumps (D. W., Gth, 2d day).
Flow of mucus from the right nostril, lasting for three days (J.
H. H, 6th).
* Irritation in the throat, posterior nares, tonsils, and fauces
(D. S. P., 3d).
An hour after taking 1st trit. an uneasy, creeping, and pressing sen-
sation about the ossa nasi, lasting about an hour, and is the sensation
experienced by most persons on putting on a pair of heavy spectacles,
if not accustomed to wear them (H. R ).
During the 1st day he experienced on the bridge of the nose a sen-
sation similar to that produced by touching it with a metallic substance.
Sticking pains about the punctum lachrymale of the left upper eyelid
(H. R, 30th).
A space about the size of a quarter dollar just above and between
the supra-orbital ridges (root of nose), felt as if pressed upon by a cold
metallic body, while within the cranium underneath there seemed to
be more warmth than usual (J. P. D., 3d).
Digest of the Symptoms. 257
Teeth and Mouth.
Pain in the molar teeth of right side (J. H. H., 6th).
Aching soreness in the teeth (D. W., 6th ; 2d day).
The 11th day much bleeding from the incisor tooth of upper jaw in
right side.
*Both corners of the mouth are chapped (C. Hg.)
Sensation of emptiness in the stomach, and very hungry within two
hours after eating a hearty breakfast ; sore on the inside of the under
lip, towards the left (A. L., 3d, 6th day).
A whitish furred tongue in the morning (J. H. H., 6th).
Three or four hours after taking the medicine in the morning, his
abdomen felt hot below the transverse colon ; his tongue is covered
with a white fur, and there is beating burning in both temples, which
he felt all day (S. A., 2d).
A small sore on the right side of the tip of the tongue, also on each
lip, continuing several days (C. E. T., 5th).
Regurgitation of wind from the stomach ; sores in the mouth on the
under lip (D. W., 6th, 2d day).
Small sore on the roof of the mouth (J. H. H., 6th).
A sore spot on the tip of the tongue (H. R., l£ trit., 4th day).
At six o'clock in the evening, after taking the medicine in the
morning, sensation of soreness on the left side of the root of the tongue,
on swallowing, accompanied with roughness and stiffness, continuing
through the night (C. E. T., 5th).
Taste as of tobacco and coffee in the mouth ; pricking sensation in
the mouth and fauces ; small spot on the left side of the tongue, which
itches ; small sore on the roof of the mouth ; itching on the left side
of the face (J. H. H., 6th).
Soreness in the roof of the mouth (H. R., 6th, 1st day).
Sensation of contraction, and burning in the roof of the mouth (H.).
Dryness in the mouth, burning of the throat and the whole breast,
with general weakness (14th dil., C. Hg.).
Much dryness of the mouth and throat at night ; obliged to drink
often ; some pricking under the back part of the tongue (H.).
Dryness in the mouth, with desire for cold water ; bad taste in the
mouth, with phlegm and ptyalism (Nd., 1st).
(Increased dryness of the throat and mouth, being obliged to moisten
and rinse the mouth every time he wakes up) (A. L., 6th).
^Inflammation, with great dryness in mouth and throat ; worse at
night. In several cases 2 i^ helped very quickly (Pehrson).
* Dryness and irritation of the throat (posterior nares, tonsils, fauces)
at night, with soreness in the morning ; secretion of tenacious mucus
during the day ; inclination to empty deglutition (D. S. P,, 3d).
On waking at eight o'clock, after taking the third trituration the
previous night, his throat is dry ; he is thirsty ; sensation as if he
had not a refreshing sleep (Rt).
Pressing contracting pain in the throat during empty deglutition (H.).
258 Cinndbaris.
Fulness in the throat, creating a desire for constant swallowing;
1st day (C. Hg.).
The cravat presses him uncomfortably, as if the throat wa3 pressed
together from below on both sides, and contracted within, so as to
impede swallowing; forenoon of ]st day (C. Hg.).
^Dryness and foul taste in the mouth (A. L., 6th).
Bitter taste in the mouth before, during, and after meals (B.).
Bitter eructations (B.).
Bitter taste in the mouth in the morning ; remains after eating (B.)
Taste of tobacco and coffee in the mouth (J. H. H., 6th).
At eight o'clock p.m., after tea, a peculiar metallic taste in the
mouth, not much unlike sulphate of zinc, or the taste left after a metal
or salt, continuing more or less one hour (1st day).
At five o'clock next morning a peculiar agreeable sensation of exhil-
aration, with a fulness extending from all sides of the chest towards
the stomach and heart, accompanied or followed by a similar sensation
in all the joints, continuing with intermissions till eight o'clock. A
peculiar drawing in the mouth after rising, until breakfast ; a small
spot on the right side of the tip of the tongue ; also on each lip, con-
tinuing several days. At two o'clock p.m., sensation in the mouth
continued ; since eight o'clock modified by a continued tendency to-
hawk and spit, with unusually large flow of saliva and mucus ; also a
sensation of warmth under the sternum, as if secretions were flowing
from the stomach, and all the mucous surfaces, as well as from the
salivary glands (C. E. T., 5th).
An increase of the flow of saliva, and a pain running near the ensi-
form cartilage, from the 7th rib on the right side diagonally through
the chest (Nd., 30th).
A great increase of the flow of urine and saliva, lasting one hour,
with shooting pains on the left side of the head, from the occiput to
the forehead ; flow of tears (Nd., 6th).
Salivation (Noack and Trinks).
Scanty, tenacious, frothy saliva in the mouth, as after long thirst,
still without thirst ; after drinking, it passes away; during the first
day(C.Hg).
Running of water from the mouth every morning before rising ;
pressure in the throat as from eating tart pears ; vanishes after getting
up (B.).
Slight accumulation of very tenacious and yellow saliva at rising in
the morning (2d day, C. Hg.).
Less mucus in the throat during third day (C. Hg.).
An increased flow of saliva (J. C. R., 2d day, 30th).
The same day from four to five o'clock p.m., a severe pain, extending
from the cartilage of the 7th rib at its junction with the sternum to the
right hypochondriac region under the inferior border of the tenth rib.
The two following days he took every night 40 to 60 globules of
30th; then again for two nights 5 gr. of j\, without any perceptible
effect until the next day, when there was increased sexual desire with
Digest of the Symptoms. 259
erections, which continued at night, terminating with an emission of
semen. The following night again Cinnab. 30th, 20 globules. The
next day an increased flow of saliva, so much so, that when he at-
tempted to speak, he found some difficulty, from his mouth being
constantly filled with saliva. He had some pain of a dull character
in the forehead over the eyes in the afternoon, which became severer
in the evening, and was aggravated by motion. Had occasional pains
in the left side of the chest, between the cartilages of the 5th and
6th ribs.
The following day the increased flow of saliva still continues ; in
the afternoon also dull aching pain in the right forehead ; worse in
the evening, when also the pains in the left side return in the region of
the heart, of a sharp cutting character, producing a difficulty of breath-
ing (J. C. K.).
(I have perceived in other cases that the effect of the remedy
often only shows itself after repeated closes ; the salivation mentioned
above is not merely to be considered as the effect of the last dose, but
also of those previously taken, and for this reason have kept intact
the whole group) (Nd.).
Stomach.
Great appetite and desire for an embrace (H.).
Great appetite, with thirst and strong sexual desires (H.).
Increases the appetite during the first day (C. Hg.).
Good appetite in the morning, somewhat rare with him, the second
day (C. Hg.).
Increased appetite in the morning, the 3d day (C. Hg.).
Strong appetite, but very soon satisfied. He feels better than usual
after meals, the 1st day (C. Hg.).
Decidedly better appetite, but less eating the 1st to 3d day (C. Hg.).
(Roast veal has a spicy taste, and like mushrooms (C. Hg.).
No appetite ; aversion to all kinds of food (H).
No appetite in the evening the 2d day (B.).
Loss of appetite ; eats very little (Nd., 1st).
Aversion to coffee (B.).
In the morning appetite greatly impaired ; but little appetite for
breakfast after taking the remedy the preceding night ; feels better in
the open air and after dinner ; pulse 60 ; skin moist and cool
(A. J. B., 2d day, 6th).
Symptoms of cold in the head ; fulness of head, discharge of much
mucus from the nostrils ; aching pain in the small of the back and
legs. Uncommon tiredness and weakness. Sensation of emptiness in
the stomach, and very hungry within two hours after eating a hearty
breakfast. Sore on the inside of the under lip towards the left (A. L.,
3d, 6th day).
Aching soreness in the teeth. Regurgitation of wind from the sto-
mach ; sores in the mouth on the underlip ; severe pain in the fore-
head, which lasts all night ; great restlessness and nervousness, a good
260 annularis.
deal of mucus at the posterior nares, which comes away in lumps
(D. W., 6th, 2d day).
After eating, a very uncomfortable feeling as if the body was swollen
and distended. Distressed feeling about the breast and stomach (H.).
Although intending to sit up and study longer, yet feeling wearied
in body and confused in mind, he soon retired. Upon lying down
there were rumblings in the abdomen, and pains passing from the epi-
gastric to the pubic region. There was also some nausea and uneasi-
ness in the stomach. Every little noise about the house troubled him,
as though it were something serious. Although accustomed to dream
much, yet he had more troublesome dreams than usual. He awoke
and started up several times without purpose ; once with a heavy pain
in the forepart of the head. Upon rising at 7 o'clock in the morning,
he felt a little giddiness and pain in the forehead, with a sensation of
soreness in the eyeballs. The acidity in the stomach, general headache
and heaviness of the eyes, to which he is subject, is much aggravated
before noon (J. P. D., 3d).
At 5 o'clock next morning, a peculiar agreeable sensation of exhila-
ration, with a fulness extending from all sides of the chest towards the
stomach and heart, accompanied or followed by a similar sensation in
all the joints, continuing with intermissions till 8 o'clock (C. E. T.,
5th), see K.
Although Cinnabaris, when taken in the stomach, is not digested,
nor forms a constituent of our bodies, it does nevertheless as an altera-
tive, wonderfully exhilarate the archseum, as long as it remains in the
stomach (Ktz.).
*Symptoms of flatulence of the stomach, irregularity of the pas-
sages, pressing in the forehead, with a sensation of congestion, to which
the prover had been subject for some time, have now nearly disappeared
(Rt., 3d).
Dizziness and lightness in the head; soreness in the stomach, with
tightness in the temples (Nd., 6th).
In the evening, pain in the head, increased to a heavy, stupefying
ache, aggravated by thinking, reading and pressure. Tenderness in the
epigastric region (A. J. B., 3d, 1st day).
Nausea, gaping and salivation, disappear on ceasing to triturate, but
the heat and swelling of the face continue (3d, L.).
Nausea in the morning at 11 o'clock, the 3d day (B.).
Nausea alleviated by windy eructation (B.).
Rising nausea in the afternoon, soon after taking the medicine (B.).
Nausea in the evening, and then a pressure on the sternum upwards,
hke from water-brash (B.).
Slight nausea and salivation (3d, L.).
Drowsiness after supper, with nausea and water-brash, a burning
from the breast upwards (B.).
Drawing sensation in the mouth, continued from 8 A. m. to 2 p. m.,
when it was modified by a continued tendency to hawk and spit, with
an unusually large flow of saliva and mucus, also, a sensation of warmth
Digest of the Symptoms. 261
under the sternum, and sense as if the secretions were flowing from th^
stomach and all the mucous surfaces, as well as from salivary glands.
(Gth, C.E. T., 1st day).
Inclination to vomit, immediately (H.).
Nausea at 9 o'clock in the eveuing, then bilious vomiting, with much
choking, and swelled face (2d day, B.).
Green vomiting, with violent choking, more in the night than in the.
morning (B.).
Anxiety about the heart, and vomiting (Geoffroy, Mat. Medica,
Leipsic, 1760, vol. 1st, page 360).
Hypochondria and Abdomen.
An increased flow of saliva the second day ; the same day, from
4 to 5 o'clock p. m., a severe pain, extending from the cartilage of the
seventh rib, at its junction with the sternum, to the right hypochondriac
region under the inferior border of the tenth rib (J. U. R., 30th).
In the morning, on rising, shooting pain in the right lobe of the liver
(C. Hg,3d).
Nausea, with occasional throbbing in the left hypochondrium ; abdo-
men distended, stools hard, and too large (A. J. B., 6th).
Soon after taking the 6th dilution, aching and somewhat sharp pain
in the left hypochondrium, in front, over a space as large as mag be
covered bg the hands, worse in moving about in the open air. Pain
soon extending around the lower border of the ribs behind, and to
region of left kidney, where it seems dull, and somewhat oppressive
(all felt, and disappeared in four hours). Soon after this, appearing in
the right hypochondrium in front, and extending around to back, and
region of right kidney, where the pain is of the same character as the
left kidney. The dull pressive pain is felt in one and then in the other
region of the kidney, alternately.
The pains intermit in severity, and those in the hypochondria are
relieved by bending forward (H.R.).
He had, also, pains of short duration in the right hypochondrium, in
middle of left breast, in front, in left kidney, and in occiput ; itching
over the body at times. In the evening, sticking pain in the region of
the left side of fifth and sixth dorsal vertebras ; a sore spot which he
felt on the third day after second trituration, on the right side of seventh
and eighth rib, as large as a wafer, with a sore pain in and around it,
continues ; during the day, there were pains at a corresponding spot on
the left side, of the same character, but without a sore spot. These last
pains, which commenced on the 5th of January, were felt occasionally,
until the 27th (H. R., 2d).
The prover remarks, that of all the pains which he experienced
during his proving, the most severe were those in the hypochondria
and kidneys (H. R.). . ,
In four hours after taking the medicine, a sharp steady pam in the
forehead, mostly in the right orbital region ; soon after felt a sharp
262 Cinndbaris.
throbbing in the left hypochondrium, in the region of the spleen, and
six hours afterwards he felt a dull aching pain in the bones of the fore-
arms and legs (A. J. B., 3d).
Pain in the upper part of the left and right lung ; an inward sore-
ness over the heart, extending along the left arm on taking a long
breath. Mucus which is thrown up, tastes like old tallow mixed with
coffee. Pain under the lower point of the sternum, extending to the
leftside under the short ribs (J. H. H., 6th).
*In diseases of the spleen (melancholy ?) (Ktz.).
Pinching in the abdomen the second day (B.).
Pinching in abdomen above and across the colon, with frequent emis-
sions of flatulence of a foetid odor, afterwards a passage the first day
(C.Hg.). _ •
Drawing pain in the abdomen for three hours in the forenoon, at
10| o'clock (B.).
•Griping colic (Ktz.).
Some griping in the bowels, the only symptom with a man, who
often took the 3d trit. (B.).
Pain in the forehead. Sticking in the chest, just beneath the sternum.
Griping pain in the bowels (J. M. R., 6th).
(After eating pickled oysters and drinking cold water, pain in the
left side of the abdomen, and much belching, without relief.) (C. Hg.)
Pain in the lower part of the abdomen, attended with diarrhoea, and
also flatulence after taking the first dose (colic from eating boiled
cabbage) (J. H. H., 6th).
During the first day and second night after taking the medicine, he
was troubled with aching pains in the thighs, soreness in the umbilical
region, obliging him to turn during the night as well as during the
day. A weak sensation in the left eye, the same day (A. L., 6th).
Pains in the head in the forenoon, with a disposition to fall asleep
while trying to listen to lectures several times, notwithstanding his
making a great effort to keep awake. Constrictive feeling in the umbi-
lical region, urine tinged yellow (A. J. B., 3d, 3d day).
Shooting pain in the bowels at intervals during the day. Flashes of
heat, confined to the abdomen, with great flatulence, more in the fore-
noon, and less in the afternoon and evening (J. L. M., T \, 1st day).
Pain in the bowels before each evacuation (J. L. M., 2d day).
Three or four hours after taking the medicine in the morning, his
abdomen, below the transverse colon, felt hot, his tongue is covered
with a white fur, and there is a beating, burning, in both temples,
which he felt all day (S. A., 2d).
Six hours after taking the 2d trit., a rumbling through his abdomen
below the transverse colon, lasting about one hour and a half (S. A.)
Upon lying clown at night, there were rumblings in the abdomen,
and pains passing from the epigastric to the pubic region. There was
also, nausea and uneasiness in the stomach (J. P. D., 3d).
Chilliness in the warm room ; an uneasy, indescribable feeling in
the abdomen (A.J. B., 1st day, 3d).
Digest of the Symptoms. 263
Sensation as if the abdomen was too large, and wishes to have
everything loose about his bowels ; numb pressing pain in the eyes ;
numb feeling in the elbow, as if the ulnar nerve was compressed ; also
numbness in the knee-joints ; hands cold ; pain in the forehead ; stick-
ing in the chest, just beneath the sternum ; griping pain in the bowels.
The pulse, which was at 12 o'clock a.m., from 44 to 52, rose at
4 o'clock to 80 (J. M. R., 6th).
Slight inclination for stool in the forenoon, but no evacuation the
first day (C. Hg.).
After taking daily the 3d trit. and during the first days he is costive;
after a week the bowels are loose (B.).
The seventh and eighth day no passage ; the ninth a regular evacua-
tion after violent straining, preceded by much wind ; afterwards pro-
lapsus of the rectum, with pain until evening (C. Hg.).
Has been disposed to costiveness during the whole time of taking
the medicine (H. R , 6th and 2d).
Constipation ; only one passage a week (Nd., 1st).
Nausea, with occasional throbbing in the left hypochondrium ;
abdomen distended; stools hard and too large (A. J. B., 6th).
Pain on the seventh rib of each side in a spot as large as a quarter
of a dollar ; more on the left side. Violent constipation, lasting all
the time he took the medicine, and for a long time after ceasing to
take any. Bleeding piles for two days ; violent itching in the anus,
worse at night in bed; a whitish furred tongue in the morning
(J. H. H., 6th).
Soft scanty stools twice a day, preceded by pinching ; less after-
wards (H).
Unusual drowsiness in the morning ; in the afternoon two passages
of the bowels, the last one with straining (Nd., 5th).
Two passages daily (H.).
(Diarrhcea after eating cheese ; afterwards great lassitude, the 4th
day) (C. Hg.).
The second day thinner stools than usual (C. Hg.).
# Bloody dysentery (Ktz.).
Slight flatulency, with a sensation as if there was to follow a large
evacuation, in the forenoon (C. Hg.).
In the evening a sensation of approaching looseness of the bowels
(H. R., 2d, 1st day).
In the morning, after rising, a loose passage, with burning in the
anus, preceded by griping (Nd., 3d).
Little pimples around the anus, with burning and itching ; thin
stools and tenesmus (B.).
After the afternoon stool, sensation of formication in the anus, as if
from a large worm, 1st day (C. Hg).
After dinner he had a feeling of weight in the lower part of the
rectum, and a sensation like aching (H. R., 2d, 9th day).
* Less protrusion of the anus during the stool the first day (C. Hg.).
264 Cinndbaris.
Urinary Organs.
Increased urination (3d, L.).
Frequent and increased emission of watery urine ; also two or three
times in the night (4th, L.).
A great increase of the flow of urine and saliva, lasting one hour,
with shooting pain on the left side of the head, from the occiput to the
forehead ; flow of tears (Nd., 6th).
Increased urination (C. Hg., 3d).
Diminished secretion in the night (1st day, C. Hg.).
Scanty urine the second and third day (C. Hg.).
Film on the urine (3d, L.).
Flaky sediment in the urine (3d, L.).
Turbid urine (J. M. R, 6th).
Pain as if from a sore in the urethra when urinating, although the
urethra is painless on pressure (H.).
Itching in the urethra in, the afternoon (Nd., 3d).
Sensation as if there was a raw spot in the centre of the urethra,
which woke him up two nights in succession (J. H, H, 6th).
* Gonorrhoea of very long standing, with much pain during urina-
tion, and soreness ; the discharge is of g, yellowish green color (Bereus).
Male Genital Organs.
A heat apparently proceeding from the genital organs, which, how-
ever, are not hot; in the summer the eighth day (C. Hg.).
Sudden and violent twitching pain through the right testicle, and in
the spermatic cord in the evening (1st day ; C. Hg.).
Twitching in the penis (H).
The penis is swollen (H).
Redness and swelling of the prepuce, having the appearance of a
sore, with painful itching (H).
(Small warts on the prepuce in different places, which bleed on
being touched) (H).
Sycosis (Noack and Trinks).
Itching pain behind the corona glandis, from which exudes matter of
a disagreeably sweet smell (H.).
Violent itching of the corona glandis, with a profuse secretion of
pus ; the itching was so violent as to cause him to rub it. which only
eased it for a short time, when it returned with tenfold violence ; two
small red spots made their appearance on each side of the glans,
secreting a large quantity of lardaceous matter. It had the appearance,
according to his opinion, of herpes preputialis (J. H. H, 6th).
Blenorrhoea of the glans penis (Noack and Trinks).
Tearing stitches in the glans penis (H.).
Small shining red points on the glans penis (H).
In the evening burning pricking itching on the extremity of the
glans penis, which disappears on rubbing, but soon returns again with
greater force (H).
* It is used externally in syphilis (Ktz.).
Digest of the Symptoms. 265
Strong erections during the night in bed (H.).
Strong erections after midnight, towards morning (Nd., 3d ; 3d day).
The seventh day, in the morning, a very violent erection, almost
amounting to priapism (C. Hg.).
Profuse sweating between the thighs ; violent erections in the even-
ing. After finishing the medicine, all desire for an embrace is lost,
which was not the case before he took the medicine (J. H. H., 6th).
A still more aggravated morbid state of mind, fretfulness ; also
sexual excitement at the least provocation (4th day, Rt., 30th).
In ^ the afternoon sexual excitement, as if he were to have an
emission, but was able to combat the feeling (2d day, Rt., 3d).
Strong sexual desires, with much appetite (H.).
Increase of sexual desires, and prolonged orgasm during the coitus
(C. Hg.).
For two mornings an almost irresistible sexual desire the seventh
and eighth day (C. Hg.).
Frequently a spiritual sexual desire, with no inclination for its gra-
tification first and third day (C. Hg.).
Sudden paroxysms of spiritual erotomania third day (C. Hg).
A pollution of a copious quantity of inodorous semen the eighth day
(C.Hg).
From the seventeenth to the twenty-third almost daily a pollution
(C.Hg).
On Tuesday night he took forty glob. On Wednesday night sixty
glob, of 30th. On Thursday night five gr. of r \, and on Friday night
ten gr. of T \, with no perceptible effect until Saturday, when there
was increased sexual desire with erections, which continued during the
night, terminating by an emission of semen (J. C. R.).
Female Sexual Organs.
Catamenia appear a day too early. Observed several times (B.).
*A few days before the appearance of the catamenia, and during
its continuance ; tearing pain in the forehead ; sensation of weakness
in the eyes ; rending pain in the spine ; tearing pains and cramps in
the bowels, with diarrhoea ; also great prostration (B.).
Leucorrhcea, causing during its discharge a pressing in the vagina (H).
*Uterine difficulties, which cannot be relieved by opiates (Ktz.).
Nasal Mucous Membranes, Cough, and Chest.
Symptoms of cold in the head, with lameness of the thighs ; much
mucus, in lumps of a dirty yellow color, in the posterior nares during
the whole week (A. L., 6th).
Symptoms of cold in the head ; fulness of the head ; discharge of
much mucus from the nostrils ; aching pain in the small of the back
and legs (A. L., 3d ; 3d day).
A great deal of cold in the head (H.).
266 Cinndbaris.
A good deal of mucus at the posterior nares, which comes away in
lumps (D. W., 6th ; 2d day).
Flow of mucus from the right nostril, lasting for three days
(J. H H., 6th).
Cough, from tickling in the throat, the third day (B.).
Dryness in the mouth ; burning in throat and the whole breast,
with general weakness, tickling in the throat, and disposition to cough
(14th, C. Hg.)
Cough, which seems to proceed neither from the breast nor from
the larynx, but from the upper part of the throat, in the morning of
the second day (C. Hg.).
(On lying down she has to cough continually ; less on sitting up ;
single paroxysms of cough, perfectly dry) (H.).
(Every evening hoarseness, with croup-like cough) (J. H. H., 6th).
Hoarseness of the voice in the morning, going off in two or three
hours (J. L. M., 2d).
Much yawning (14th, B.).
In the forenoon, while riding in the open air, very frequent slight
yawning, with chilliness. As soon as he enters a warm room it dis-
appears, during warm autumn weather (C. Hg.).
Chest somewhat oppressed ; larynx asthmatic, in the morning of
second day (C. Hg.).
After conversation a pressure in the upper and central part of the
chest, which renders breathing laborious ; he is obliged to bend for-
ward, in order to inhale sufficient air ; the forenoon (C. Hg.).
The chest often seems contracted, as though pressed upon ; he is
obliged to stretch himself, in order to breathe easily; the first and
eighth day, only during the day and particularly in the forenoon (C. Hg.).
He awakes suddenly after midnight as if from a dream, as if he has
no breath ; a state resembling nightmare (H).
Half an hour after taking the medicine, dyspnoea with heat, the same
morning violent pains in all the limbs, commencing in the points of
the fingers, and worse in the left side ; at the same time weakness,
burning in the throat and breast ; dryness of the mouth and cough,
incited by tickling in the throat (i 4, Fr. Husmann).
At five o'clock in the afternoon pressing pain in the centre of the
chest, similar to a cramp of the stomach, to which she formerly had
been subject. The pain extends to the throat and between the shoulders,
and lasted until night. The spot was still sensitive on the following:
day(B.).
Sticking pain in the chest, just beneath the sternum (J. M. R., 6th).
Pain in the upper part of the left and right lung ; an inward sore-
ness over the heart, extending along the left arm, and on taking a long
breath. Mucus, which is thrown up, tastes like old tallow mixed with
coffee. Pain under the lower point of the sternum, extending to the
left side under the short ribs (J. H. H., 6th).
From 4 to 5 o'clock p.m., after taking the medicine (30th dil.) the
previous evening, a severe pain, extending from the cartilage of the
Digest of the Symptoms. 267
seventh rib, at its junction with the sternum, to the right hypochon-
drium under the inferior border of the tenth rib. After two more doses
of the 30th, and two of T \, in four nights, and then again one of the
30th, he had on the 6th day occasional pains in the left side of the
chest between the cartilages of the fifth and sixth ribs, and without
another dose'on the seventh day ; in the evening again a return of
the pains in the left side of the chest in the region of the heart, of a
sharp cutting character, producing a difficulty of getting breath while
they continued. On the eighth day, forenoon, again a return of the
sharp cutting pain in the region of the heart, followed by wandering
pains throughout the whole chest (J. C. R.).
Pain on the seventh rib of each side, in a spot as large as a quarter
of a dollar, more on the left side (J. H. H.^ 6th).
An increase of the flow of saliva, and a pain running near the ensi-
form cartilage, from the seventh rib on the right side diagonally
through the chest (Nd., 30th).
The fourth day, after 2d trit., itching on the body and canthi, and a
spot on the right side on one of the ribs (7th or 8th) as large as a
wafer, very sore to touch, with occasionally a sore pain in and around
it, which continues for three or four days.
During the fifth day there were pains at a corresponding spot on the
left side of the same character as the pain connected with the other, but
without a sore spot.
On the fifth day, after 2d in the morning, there were also pains of
short duration in the right hypochondrium, in middle of left breast in
front, in the left kidney, and also in occiput (H. R.).
(In the evening nervous trembling of the heart with anxiety, to which
she had formerly been subject, again returns) (Nd., 6th).
Within ten minutes after taking 14th, a very severe pain in the
heart, as if it was twisted around (C. Hg.).
Soreness under the right breast, near the last true rib, particularly on
drawing breath (Nd., 1st).
(A stitch about the eighth rib, particularly on taking a long breath,
occasionally on the fourth day) (Nd., 3d).
At five o'clock a.m , a peculiar agreeable sensation of exhilaration,
with fulness, extending from all sides of the chest, particularly the
thorax, towards the stomach and heart, accompanied or followed by a
similar sensation in all the joints, continuing with intermissions till
eight o'clock* (C. E. T., U day ; 5th).
Back and Kidneys.
On turning the head, pain in the right side of the neck, below the
sterno-cleido-mastoideus muscle. Pain in the back part of the neck
when the head is thrown back, extending to the occiput. The muscles
of the back part of the neck seem as if contracted (J. H. H., 6th).
* Considering the previous state of the prover, these symptoms may probably
be considered curative.
268 Cinndbaris.
Eruption on posterior cervical region, and soreness from tbe right ear
into the middle of posterior cervical region, as if the glands were
affected, second day. This soreness increased on the third day, and
was very severe in the evening. It continued until seventh day, but
gradually decreased in severity (Rt., 6th).
About 4 a. m., the fifth day after taking second, he was awakened by
a dull sticking pain in the region of left kidney, which lasted but a short
time ; afterwards tossing about and sleeplessness for an hour ; after
rising from bed, a fulness and pressure in the occiput and back of the
neck, continuing with much severity till about noon, after which, the
symptoms somewhat abated ; heaviness and sleepiness during the day ;
pains of short duration in the right hypochondrium, in middle of left
breast, in front of left kidney, occiput ; itching over the body at times.
The pains experienced in the hypochondria and kidneys were most
severe.
In the evening of the same day, sticking pain in the region of the
left side of the fifth and sixth dorsal vertebrae ; the sore spot on right
side, felt two days previously on one of the ribs (seventh and eighth),
as large as a wafer, and sore to touch, with occasionally a sore pain in
and around it, continues ; during the day there were pains at a corre-
sponding spot on the left side, of the same character as the pain con-
nected with the other, but without a sore spot.
The sixth day after 2d trit., occasionally a sticking pain on the right
side of the same dorsal vertebrae (fifth or sixth) ; pain sometimes in
the left side of occiput (organ of amativeness), itching of eyelids and of
various parts of the body ; sore spot in the right side continues. The
pains on the side of the fifth and sixth dorsal vertebrae have been
occasionally felt until the eighth day (H. R.).
In ten minutes after taking the 3d trit. at night, he felt a warm glow
through his legs, which was soon succeeded by a dull pain in the left
arm just above the elbow, and by occasional darting pains in the lower
extremities. There was also a dull pain in the lower dorsal portion of
the spine, continuing only for a short time. A space about the size of a
quarter dollar, just above and between the supra-orbital ridges, felt as
though pressed upon by a cold metallic body, while within the cranium
underneath, there seemed to be more warmth than usual (J. P. D.).
The third night, after taking the 3d trit., he had restless sleep, with
many dreams, and feels tired in the morning, with aching across the
small of back, and limbs. This pain continued the fourth, fifth, and
bixth day. Again, all the seventh night and next day, he had severe
aching and drawing pains in the back, from the region of the kidneys
to sacrum, and in the thighs and legs. Drawing up the legs affords
relief. The eighth day, also, slight pains in the back and legs, but
much better than the day before. All these symptoms from one dose
of 3d (A. L.).
Soon after taking the sixth dilution, an aching and somewhat sharp
pain in the left hypochondrium, in front, over a space as large as may
be covered by the hand, worse on moving about and in the open air.
Digest of the Symptoms. 269
Pain soon extending around the lower border of the ribs behind, and
to region of the left kidney, where it seems dull, and somewhat oppres-
sive (all felt and disappeared in four hours). Soon after this, appearing
in right hypochondrium in front, and extending around to the back,
and region of right kidney, where the pain is of the same character as
in the left kidney.
The dull pressive pain is felt in one and then in the other region of
the kidney, alternately. The pains intermit in severity, and those in
the hypochondria are relieved by bending forward (H. R.).
One hour after taking the sixth dil., rush of blood to the back part
of the head, attended with violent itching and heat, extending to each
ear, and behind the left ear ; there came three hard lumps, one the size
of a small shot, the other that of a buckshot, and the last a size larger.
On the same night, he felt a sharp pain in the region of the kidneys, as
if some one had driven a nail on each side of the vertebrae. More
profuse discharge of clear water (J. H. H.).
General pain all over the back, down to the loins, worse after every
dose of medicine, aggravated on drawing a long breath (J. H. H., 6th).
Sore feeling, extending from the small of the back around both sides,
over the ossa ilii, worse on pressure (J. H. H., 6th).
Aching in the small of the back, as if bruised (Nd., 5th).
Shooting pain in the region of the loins and sacrum, increased by
stooping, and during labor (B.).
Tearing pains in the back from above downwards at 11 o'clock in
the evening and through the night, so that she could get no sleep ;
second day (B.).
Rending tearing pain in the side of the back, as if it was broken,
particularly at night, upon the least motion in bed, and in the arm
when writing ; these pains are relieved by the warmth of the stove (H.).
Upper Extremities.
Pain in the left shoulder, between the clavicle and scapula, interiorly
the first day (C. Hg.).
In the evening of the second day occasional shootings in the upper
part of the left temple along temporal ridge ; dulness in the whole
head, especially in the forehead just over the eyes ; lame sensation in
the right shoulder-joint (H. R., 6th).
After taking the medicine in the morning towards 10 o'clock, a
pressing pain in the right shoulder, as from a blow, which continued
for half an hour, then pain in the abdomen (B.).
Sudden pain in the middle of the upper part of the right arm, as
though it would fracture, the third day (C. Hg.).
Pressing gnawing pains in the upper part of the right arm, as if
' they were moving about in the bones to and fro in the forenoon of the
fifth day (C. Hg.). _
Violent shooting pains in the arms at times (H.).
Shooting pain in the muscles of the inner side of right os humeri
early in the morning after rising the third day (B.).
270 Cinnabar is.
Shooting pain on the outer side of the right fore-arm, from 4 o'clock
p.m., until bed time (the 3d day, B.).
He was awakened several times from sleep by a severe pain in the
right arm. It continued in the morning and during the day, at times
very severe, commencing about the centre of the os humeri, and
extending to the elbow and along the radius to its inferior extremity ;
the pain was of a heavy, aching character, deep-seated, and caused
lameness and difficulty in moving the arm. In the forenoon he had
also a return of the sharp-cutting pains in the region of the heart,
followed by wandering pains throughout the whole chest (J. C. R.,
3d day, 30th dil., and after several larger doses previously taken).
Sensation of lameness in the right arm, the eighth day ; the day
before, wandering pains as if in the bone and pressing in the muscles
(C. Hg).
In the evening numbness of the arm on which he lies and supports
himself, until the 13th day (C. Hg.).
Four hours after taking the 3d trit. he felt a sharp steady pain in
the forehead, mostly in the right orbital region; soon after felt a
sharp throbbing in the left hypochondrium, in the region of the spleen,
and in about ten hours after the above dose, at ten o'clock p.m., he
felt a dull aching pain in the bones of the forearms and legs.
Taking three days afterwards another dose of the same trit., at
11 o'clock a.m., he felt in half an hour a sharp aching pain in the
right supra-orbitary region, shooting backwards and downwards to the
ear and side of the neck. Front of the head very hot ; the pain is
worse in the warm room, and on moving the eyes and scalp ; chilliness
in the warm room ; an uneasy indescribable feeling in the abdomen ;
numbness of the left arm, from the elbow down to the end of the
little finger. Next morning all the symptoms are better, but in the
evening, at 8 p.m., the headache, which had increased at 10 o'clock
the previous evening to a heavy, stupefying ache, aggravated by think-
ing, reading and pressure, returned with a numbness and heavy aching
in the arms and knees and lower legs, without a new dose being taken
that day. The pains are all aggravated in the evening ; better in the
open air, and after eating and sleeping (A. J. B.).
Dull aching in the bones of the forearms and legs ; numbness of the
left arm, from the elbow to the end of the little finger, passing off on
using the arm, and returning again while at rest (A. J. B., 1st
day; 6th).
Pain in the left side of the head, temple and supra-orbital ridge ; sen-
sation as if the abdomen was too large ; he wishes to have everything
loose about it ; numb pres&ing pain in the eyes ; numb feeling in the
elbows, as if the ulnar nerve was compressed ; also numbness in the
knee-joints ; hands cold (J. M. R., 6th ; 1st day).
In ten minutes after taking the 3d trit. in the evening, he felt a
warm glow through his legs, which was soon succeeded by a dull pain
in the left arm just above the elbow, and by occasional darting pains in
the lower extremities. There was also a dull pain in the lower dorsal
vertebrae of the spine, continuing only for a short time. A space about
Digest of the Sym/ptoms. 271
the size of a quarter of a dollar just above and between the supra-
orbital ridges, felt as though pressed upon by a cold metallic body ;
while within the cranium underneath, there seemed to be more warmth
than usual. *A dull pain felt before in the left temple and side of the
forehead disappeared — urgent desire to urinate (J. P. D.).
Pain along the left arm, particularly in the little finger, third finger
and thumb. On supinating the forearm, the pain is worse at the
elbow. It feels as if the " crazy bone" was struck. The least twitch
causes the elbow and shoulder to crack. Itching in the palms of the
right hand. Pain in the little finger of right hand. Itching in the joint
of right hand. Pain in the little finger of right hand. Itching in the
joint of right hand (J. H. H. 6th).
A constant pain in the left arm-joint when turning and straightening
the arm, and when writing (J. H. H. 6th).
In about an hour after taking 30th, sharp darting pains like electric
flashes passing from the first phalanx of the ring-finger of the right
hand to the middle of the forearm, and from the lower extremity of
the radius of the left arm up to the elbow (J. C. R.).
The first joint of the right index-finger red and hot, but painless ;
next morning chill, with perspiration under the arms ; cannot get
warm, even near a hot stove (3d L.).
Joint of the first finger of right hand is red and hot (4th L.).
Pain in the left thumb, as if pierced by splinters of glass ; (six or
eight weeks before he had wounded his thumb with glass) (the 3d day,
C. Hg.).
In two hours after taking the medicine a fulness and general pres-
sure in the whole head, as after taking cold, with dull aching pain in
the region of benevolence ; better in the open air ; great drowsiness
and lassitude in the warm room. Occasional shooting and prickling
pain in the two middle fingers of left hand, better by firm pressure
upon the thumb. The above symptoms continued about eight hours
(C r L. M. 6th).
Lower Extremities.
During the first night after taking the 6th dilution, drawing, aching
pains in the thighs from the hip-joints nearly down to the condyles,
aggravated by moving, and accompanied with great lameness, expe-
rienced on getting up and attempting to walk ; getting better after
walking a short distance. The two following days symptoms of cold in
the head, with lameness of the thighs (A. L.).
Two hours after taking the 6th dil. in the morning, on straining at
stool, shooting aching pain on posterior side of right thigh, from the
hip-joint to middle of os femoris.
After a new dose of the 6th in the evening, a day after taking the
last dose, he was troubled next day and night with aching pains in the
thighs, soreness in the umbilical region, obliging him to turn during
the night as well as during the following day. Also violent itching
and pricking in the inner side of the knee-joint, ever since he has com-
T
272 Cinnabaris.
menced to take the medicine ; worse in the night and the morning
before getting up.
The 5th day violent itching on the inside of the thighs, knees and
legs, worse at the knees, especially at night (A. L.).
From the 2d to the 5th day after the 3d trit., aching pains in the
small of the back and legs, with uncommon tiredness and weakness,
and on the fifth night and sixth day severe aching and drawing pains
in the back, from the region of the kidneys to sacrum and in the thighs.
Drawing up of the legs affords relief. The pains in the back and legs
still continued in a slight degree on the 6th day (A. L).
Tearing pains from the right hip-bone to the great toe, commencing
at 9 o'clock in the evening, lasting through the night, and only dim-
inished in the morning after rising (B.).
At \0\ p.m., after taking the 3d decimal trit. in the morning, pain
and tired feeling in the right hip, and afterwards in the left. Tired
feeling in all the joints of the lower extremities, better from rising and
walking ; sensation of having taken cold and general feeling as not
being fit for any mental labor, depressed ; melancholy, cynical, state of
mind ; nervous system excited.
On the fourth night itching, especially on the inside of the
thighs (Rt).
An eruption on the inner and lower part of the thigh, with itching
(D. W. 6th, 2d day).
Fetid and excoriating perspiration between the thighs when
walking (H.).
Profuse sweating between the thighs (J. H. H. 6th).
Tearing pain in the left thigh bone the whole day (3d L.).
Tearing in the right thigh bone (4th L.).
(Rheumatic) pain of right knee-joint, increasing for two weeks,
aggravated during walking, but most violent when ascending stairs ; it
disappears during rest (4th L.).
Itching in the palm of the right hand. Pain in the little finger of
right hand. Itching in the joint of right hand. Pain in the knee-
joint, worse at noon, while walking. Drawing in all the muscles of
the lower extremities on the under surface. Sore feeling on the ankle,
attended with heat and itching over the whole leg (J. H. H. 6th).
Numb feeling in the elbows, as if the ulnar nerve was compressed,
also numbness in the knee-joints (J. M. R. 6th, 1st day).
In the forenoon of 2d day after 1-J trit., head full, nervousness and
irritability for a short time, also for a short time sticking pain in the
back part of left knee-joint ; in the afternoon a slight pain in right
knee-joint, similar to the pain in the left one, with a creeping sensation
above and below it, seemingly about the bone, lasting about an hour.
The above pains in the knee-joints have been felt occasionally every
day for four days (H. R.).
"Frequent pain in the lower side of left knee, near the inner side of
tibia, lameness and frequent slitches on walking, particularly the inner
side of knee-joint (C. E. T. 5th, 2d day).
Digest of the Symptoms. 273
Awakened in the night by a painful twitching in the lower part of
the leg (H.).
Lassitude in the lower part of the legs, more in the afternoon ; after
5 days (B.).
In 10 hours after 3d. trit. a dull aching pain in the bones of the
fore-arms and legs, and in four days a numbness and heavy aching in
the arms, knees and lower legs (A. J. B.).
Dull aching in the bones of the forearms and leers (A. J. B. 6th, 1st
da ?)- ...
In 10 minutes after taking the 3d. trit. in the evening, he felt a
warm glow through his legs, which was soon succeeded by a dull pain
in the left arm-joint just above the elbow, and by occasional darting
pains in the lower extremities (J. P. D.).
Pain in the tendo achillis and os calcis after walking (J. M. R. 6th.).
Pressing sensation in the foot as if it would fall asleep (H.).
(Rheumatic pain in the large toe.) (H.)
Cold feet day and night (B.).
Coldness in the joints ; shuddering and drawing in the arms and
legs (H.).
* Wandering gout (Ktz.).
Skin.
A red itching spot, as large as the end of the thumb, on the right
side of the forehead (B.).
Red herpetic spots on the forehead, particularly over the right eye-
brow (B ).
Redness of the skin like a chronic eruption (Nd. 1st.)
Two small red spots made their appearance on each side of the
glans penis, secreting a large quantity of lardaceous matter. It had
the appearance, according to his opinion, of herpes preputialis (J. H. H.
6th.)
A pricking itching on the anterior part of the neck, with swollen
glands, and in front on the chest; red points make their appearance
converging into round spots, full of hard granular pimples; the itching
of the eruption increases on scratching it, finally the sj>ots are painful
Rush of blood to the back part of the head, attended with violent
itching and heat extending to each ear, and behind the left ear there
came three hard lumps, one of the size of a small shot, the other of a
buck-shot and ihe last a size larger (J. H. H. Gth.).
In the evening violent itching on both shoulders, on which red
streaks appear after scratching; besides that, small red elevations are
to be observed, the itching from which is almost insupportable. After
going to bed it disappears (C. Hg. 1st day).
In the morning red papulous eruption, without itching, on both
elbows, left one the worst (9th day, C Hg ).
An eruption on the inner and lower part of the thigh with itching
(D. W. 6th, 1st day).
274 Cinnabaris.
From the first time he took the medicine, he felt as if pimples were
to come out over his body, with a general uneasy sensation and itch-
ing (The prover had this feeling for some time, but now in an aggra-
vated form (Rt. 30th & 3d).
* On the finger a red eruption, sometimes with pustules filled with
yellow matter, the same under the right knee, with occasional itching
(Nd. 3d).
* Chronic impetigo (in a man who bad gonorrhea some twenty
years ago) pustules and scabs on the upper lip immediately under the
nose, right nostril also somewhat tumefied (Nd. 3d).
* Chronic impetigo in another man on the same spot as the above
(Nd. 3d).
* Does well in scabies ferina (Ktz.).
* Small pox (Ktz).
* It especially purifies the blood (Ktz).
* It is useful in gangrenous ulcerations. Ebn. Dsschold.
A cut in shaving bleeds very little (C. Hg.).
Itching of the lids of both eyes (J. H. H.).
Shooting pains in the inner canthus of right eye, with a burning
and itching (J. L. M.).
Itching on the body and canthi (H. R).
Itching of eyelids and of various parts of the body (H. R.).
In the eyes for two days excessive itchine: of the inner canthi
(CRT.). / b
From 9 to 12 o'clock, itching on the outer canthi, severe and fre-
quent, with a sense of stiffness in the upper lids (C. E. T.).
Much itching in the left ear, from the 1st to the 4th day, scurfy
eruption in the right external ear, between the helix and antihelix
(C. Hg.).
Much itching in the right ear (C. Hg.).
Itching on the left side of the face (J. H. H.).
Itching of the nose with bleeding after blowing it. The blood is
very dark. The itching is caused by pimples in the right nostril
(J. H. H.).
Small spot on the left side of the tongue which itches (J. H. H.).
Itching on the palm of right hand. Itching in the joint of right
hand (J. IT. H.).
Violent itching on the inside of the thighs, knees and legs, worse at
the knees, especially at night (A.. L.).
An eruption on the inner and lower part of the thigh, with itching
(D. W.).
Itching at night, especially on the inside of the thighs (Rt.).
Violent itching and pricking on the inner side of the knee-joint, ever
since he commenced to take the medicine, worse in the night and in
the morning before getting up (A. L.).
Sore feelino- of the ankle, attended with heat and itching over the
whole leg (LH. H).
Violent itching at the anus, worse at night in bed (J. H. H.).
Digest of the Symptoms. 275
Violent itching of the corona glandis, with a profuse secretion of
pus (gonorrhea glandis), the itching was so violent as to cause him to
rub it, which only eased it for a moment, to return with tenfold vio-
lence (J. H. H.).
Itching on various parts of the body, while walking in the open air
Itching over the body at times (H. R.).
Sleep.
After dinner an unconquerable desire for sleep. (For a long time he
has not been in the habit of sleeping after dinner.) (3d L.)
Less desire to sleep after eating (3d day, C. Hg.).
Feeling excessively sleepy at 1 o'clock in the evening, she went to bed
and slept well through the whole night (2d day, B.).
Great desire for sleep in the evening, for several days, in the case of
several provers (B.).
Increased sleepiness in the evening (3d day, C. Hg.).
Great sleepiness in the evening (13th day, 0. Hg.).
At 11 o'clock a.m., pains in the head return again with a disposition
to fall asleep, while trying to listen to the lecture, notwithstanding his
making a great effort to keep awake (3d A. J. B., 3d day).
Disposition to sleep during the day (J. H. H., 6th.).
A dull, heavy and sometimes a sleepy feeling during the day (A.
L., 1st day, 3d.).
Weakness and sleepiness in the eyes about noon ; could scarcely keep
them open (A. L., 3d, 6th day).
Head full, heavy, with strong pulsations of the temporal arteries;
great inclination to sleep during the day (H. R., 1^-, 3d day).
A dull, heavy and, at times, a sleepy feeling during the day (A. L.,
3d, 1st day).
Weakness and sleepiness in the eyes at noon ; he could scarcely keep
them open (A. L , 3d, 6th clay).
Heaviness and sleepiness during the day (H. R, 5th day, 1|- trit.).
At 11 o'clock a.m., unusual drowsiness and heaviness over the eyes
(Nd., 1st day, 5th).
Unusual drowsiness in the morning (Nd., 1st day, 3d).
Nightly sleeplessness without pain and fatigue; he feels strong in the
morning as if he had no sleep necessary (H.).
Sleeps an hour only ; after eight days (B.).
He awakes very early but feels too indolent to rise and falls asleep
again (1st week, C. Hg.).
Awakes early (C. Hg.).
Loss of sleep during the forepart of the night. Restless and tossing
about during the whole night with anxious dreams, which he is wholly
unable to recall after waking (A. J. B., 6th, 2d night).
Nightly sleeplessness ; hears the clock strike all night. He awakes
up suddenly as from a dream (Nd., 1st).
276 Cinnabaris.
Before going to bed took the 30th dil. Slept very well but had very-
vivid dreams, which he could not remember. After taking the same
dilution the next night, he felt a drowsy sensation as if he would readily
sleep. But on going to bed, at 12 o'clock, the drowsy sensation con-
tinued, with very strong desire to sleep ; he could not sleep, however,
on account of a very disagreeable nervous sensation which caused him
to toss about in bed for an hour and a half. He did not sleep so well
as the night before ; his dreams were vivid and rather pleasing, but he
could not bring them to his recollection. After taking the same dilution
again the third night, he is again restless and has vivid dreams. On
the fourth night he took 5 gr. of 3d trit. He felt no desire for sleep
but sat up and read until half past 1 a.m. He did not sleep for half an
hour after going to bed. He dreamed continually but not so vivid as
before. On waking at 8 o'clock his throat is dry ; he is thirsty ; sen-
sation as if he had not had a refreshing sleep (Rt.).
After retiring did not sleep for over an hour but tossed about ; very
nervous and mentally vexed (Rt, 6th.).
Restlessness and sleeplessness at night from a constant flow of ideas
changing from one subject to another (J. C. R., 30th) (1st night).
First night after taking 6th dil. ; restless, uneasy sleep ; second night
after, the same dil. Increased restlessness, with constant dreaming;
seemed to dream before getting asleep (D. W.).
The 5th night after taking the 1^- trit. ; tossing about and sleepless-
ness for an hour, after being awakened at 4 a.m., by a dull sticking pain
in region of left kidney, which lasted but a short time (H. R.).
Sleep restless with vivid dreams, but he cannot remember them in
the morning (J. M. R., 6th).
After taking the 6 th dil , on going to bed, great restlessness at night ;
continual dreaming and waking. He would scarcely be lost in a drowse
before he would be dreaming. Vivid dreams of studies and business.
The 2d night, after taking again the same dose ; he had many
dreams and waked up often.
The 3d clay ; the same dil., in the morning. In the night continued
restlessness, and dreams that a lump is in his throat and right ear.
The 5th night ; again the same dose. In addition to the restlessness
and dreaming he woke up with a throbbing pain in the organ of con-
scientiousness, extending to forehead over the eye.
The 7th night, without a new dose, he had vivid dreams of the
lectures, particularly the anatomical. He could not believe that he was
not actually there.
After taking at bed-time the 3d trit., he had several dreams and
woke up several times through the night.
The 3d night, without a new dose ; restless sleep with manv dreams
(A. L.).*
* It will be perceived from this symptom, as well as several others that the
restlessness and sleeplessness so frequently experienced at night did not depend
upon the medicine being taken at night. Cinnabaris evidently produces sleepless-
ness at night and sleepiness in day-time.
Digest of the Symptoms. 277
Dreams with much talking during the sleep, which is very restless
(J. H. H., 6th).
Although accustomed to dream much, yet he had more troublesome
dreams than usual. He awoke and started up several times without
purpose : once with a heavy pain in the forehead. In one of his dreams
he saw a spider as large as an ox (J. P. D., 3d, 1st night).
Dreams of the events of the day (2d day, B.).
Dreams of unimportant events, sometimes to be remembered, some-
times not (3d day, C. Eg.).
Vivid dreams of a sensual nature (Nd., 5th).
Frightful dreams the 3d day (B.).
Does not remember his dreams in the morning, but they occur to him
long afterwards (3d day, C. Eg.).
Fever.
Feeling of coldness and sensation of inertia, drowsiness (Nd. 1st).
Chilliness in the warm room (A. J. B.).
Skin moist and cool; pulse 60 (A.J. B. 3d day).
Hands cold (J. M. R. 6th).
Chilliness in the morning, with perspiration under the arms ; he
cannot get warm, even near a hot stove (3d L.).
Front of the head very hot (A. J. B. 3d, 1st day).
A heat when in bed during the night, that seems to ascend from the
stomach into the neck and head, disappearing after rising (H.).
Internal and external heat of the body during the whole night ;
chilliness in the morning on rising; gripings, thin passage, and con-
tinual weariness of the whole body after nine days (R).
He cannot endure the heat of the sun in his room (1st day, C. Hg.).
Heat as from hot weather, mostly on the right side of the head, and
on the breast and arms, but worse on the left arm (1st day, C. Hg.).
* Some use it as an amulet in inflammatory fevers (Ktz.).
Seems to lower the pulse in the forenoon and make it irregular.
The pulse, which was at 12 o'clock a.m. from 44 to 52, rose at 4
o'clock p. m. to 80 (J. M. R. 6th).
Pulse at noon 60 ; in the evening 80 (D. W. 6th, 1st day).
Profuse sweating between the thighs. All the other symptoms
are most violent at night in bed, but the sweating is worse at 12
o'clock in the day (J. H. H. 6th).
Though in itself not a sudorific, yet it possesses many virtues (Ktz.).
General Symptoms.
Sensation of lameness in all the limbs ; he is indolent and
sleepy (H.).
Pain in all the joints, with lameness during the day (D. W. 6th).
Weariness, no disposition to labor (2d day, B.).
Feels very languid ; he would go to bed if he had the time (3dL.).
278 Cinndbaris.
Great excitement to activity, alternating with lassitude ; the weari-
ness of the body is better after a short repose (4th day, C. Hg.).
Tired and prostrated, particularly before and after eating; better
when riding in the open air, but only for a short time (the first 4
days, C. Hg.).
In the morning a sense of general prostration ; great weakness of
all the limbs. Feeling of depression, and weakness of the whole
system as after a severe illness (A. J. B. 6th, 1st day).
Lassitude, weariness, feeling as if an attack of typhus fever were
to come on (J. H. H. 6th).
Uncommon tiredness and weakness (A. L. 3d, 5th day).
Feeling of cold and sensation of inertia ; drowsiness (Nd. 1st).
Great drowsiness and lassitude in the warm room (C. L. M. 6th,
1st day).
Nervousness and irritability about noon, for a short time (H. R. l£,
2d day).
A peculiar nervous thrill pervading the whole frame, even to the
fingers and toes, affecting especially the joints. Sense of languor and
depression, as after excessive exhilaration or intoxication. The above
sensation continued without intermission for three days (C. E. T. 5th).
Unusual irritability during the whole time since he took the medicine
(D. W. 6th).
The next day after taking the 30th, general nervous, uneasy sensa-
tion (Rt).
Characteristics and Conditions.
Pains all aggravated in the evening.
Feels better in the open air and after dinner (A. J. B.).
All the symptoms except the sweating are most violent at night in
bed. The sweating is worse at 12 o'clock in the day (J. H. H.).
The headache is much worse after sleeping (Nd. 1st).
The pains intermit in severity, and those in the hypochondria are
relieved by bending forward (H. R.).
The first and second day more symptoms during the day (C. Hg.).
Its action continued nine days (H.).
Many pains resemble the slow and great movement of an irresistible
power (C. Hg.).
Cinnabaris has four times as many symptoms in the left arm as in
the right, and two symptoms on the left side of the face and tongue,
and one on the left breast, but none on the right side of those organs.
It has three symptoms on the right supra-orbital region, one on the
right side of the head, nostril, shoulder-joint and thigh, but none on
the other side of the same parts of the body.
The symptoms in the other parts of the body seem to be nearly
equally balanced between the right and left side.
As it seems to produce sleeplessness at night and sleepiness in the
day-time, it will probably become an important remedy for these two
Digest of the Symptoms. 279
conditions, and in two cases, where the former symptom was present,
it has been very beneficial.
5. Therapeutic Use.
With regard to the action of Cinnabaris there yet reigns doubt;
some consider it as entirely powerless, and others as a virulent and
deadly poison. According to Wibmer, there is more ground for the
former than the latter opinion. (How does he know ? He himself
confesses, that farther experiments must clear up the point.) {Wibmer,
Wirkung der Arzneimittel und Gifte.)
Pure Cinnabar is very highly prized on account of its marked
effects in the worst diseases (Ktz.).
Although Cinnabaris, when taken into the stomach, is not digested,
nor forms a constituent of our bodies, it does nevertheless as an alterative
wonderfully exhilirate the arch^eum, as long as it remains in the
stomach (Ktz. See C. E. T.).
Mercury in combination with sulphur, as in Cinnabar., has not the
same power, nor does it cause, bound by this fetter, the same evils as
without it (Ktz.).
Crato says, (Ep. 7) that the strongest constitution can hardly endure
its effects (Ktz.).
Fernelius de Ven writes, that horrible effects had followed the use
of Cinnabar. But in the case mentioned it is doubtful whether the
painter suffered from the effects of the natural Cinnabar, or from the
orpiment (Ktz.).
It is the most reliable antidote to poison (Ktz.).
It exalts the virtues of other medicines (Ktz.).
•Furitiere says in his book it is a poison.
Native Cinnabar, as an impalpable powder, is almost a universal
mediciue — 10 to 30, 40 gi\, or a drachm, for 40 — 60 days, taking it
always at bed-time (Lemery).
Cinnabar is seldom used inwardly but for horses (Pomet).
There is a great deal of danger in painting the face with it, and bad
consequences may follow (Lemery).
There is a strengthening power attributed to it, and therefore it is
given in all desperate cases (Ktz.).
Sometimes the best native cinnabar excites nausea ; vomiting, anxi-
eties, heat, burning, etc. (J. Hill).
Native Cinnabar will not produce salivation, but the artificial will,
speedily and easily (Lemery).
Cinnabaris is an excellent anti-venereal, expels the pox and all foul-
ness out of the whole body, with all its consecpuences ; it sweetens the
blood, takes away all manner of pains and aches in any part, all man-
ner of swellings, ulcers and nocturnal pains. Kills worms (Lemery).
Specific for falling sickness, excellent for vertigoes, apoplexies, pal-
sies, lethargies and all diseases of the head and brain (Lemery).
280 Cinnabaris.
Cinnabar is used in epilepsies, vertigoes, madness and all spasmodic
affections (J. Hill).
Internally Cinnabaris is seldom used, except that it is an ingredient
of several pulveres anti-eptilepticos (Ktz.).
It possesses the power of alleviating pain, particularly in epilepsy
(Ktz.).
The celebrated Sennert used it in the form of powders against epi-
lepsy (Ktz.).
Crato, (ep. 137) doubts the magnetic power of Cinnabaris against
epilepsy (Ktz.).
Cinnabaris does wonders externally, if tied on the pulse (in the case
of a person of high rank, lying sick with the small pox, and who had
spasms) (Ktz.).
Cinnabaris cured in the case of a somnambulist a fever induced by
the effects of sweet marjoram, but produced at the same time the most
terrible spasms.
Cinnabaris is beneficial in indolent ulcers (Ebn. Dsschold).
It is beneficial in mortification and malignant pustules.
It arrests hemorrhages.
It is good in all salves and plasters (Garde de Sundheyt Lubeck
Steffen Arndes, 1510).
Cases.
J. C. Pain in the back of the neck shooting to occiput with stiff-
ness and hard swelling of the glands at the back of the neck ; these
symptoms were relieved by Cinnabaris 12.
B. L., set. 3, of pale complexion, had formerly eruptions on the scalp,
which were cured by Sulphur. She now has a soreness on the scalp
on touching, with a pain in the left side of the head, about the organ
of conscientiousness. One or two doses of Cinnab. 12 permanently re-
moved the above symptoms.
Mrs. D. Pain from back of neck to back of head, behind the ear,
shooting to forehead ; cured by Cinnab. 30.
Kev. 0. Heaviness from one temple to the other to occiput, cured
by Cinnab. 12.
Ten similar cases, characterized by pain from occiput to forehead,
only varying in some slight symptoms, were all cured by Cinnabaris
12 and 30. The majority of these cases were cured by Cinnab. alone;
a few required other remedies for their final removal.
Four other persons also received the remedy for similar symptoms,
but they did not return, in order to report their cure.
The observation of "Schroeder" in his " Arzneyschatz" that
Cinnabaris is a great " Specijicum cephalicum " is no doubt correct.
Provings of Jjfercurius-sulphuricus. 281
12.— MERCURIUS - SULPHURICUS.
By C. Neidhard, of Philadelphia.
MERC - SULPH. Yellow Sulphate of Mercury, Turpeth mineral.
For the purpose of affording a comparison with the Cinnabaris we
add two experiments by those efficient provers, Drs. Hamilton Ring
and J. C. Raymond, with the Sulphate of Mercury.
First Proving ; Second and Third Triturations.
Dr. Hamilton Ring. — The remedy was prepared by Dr. Hering.
Each powder contained two grains of the third trituration.
11 a.m. Took first powder.
On the evening of the day on which the powder was taken an un-
usually comfortable feeling in the head and increased clearness and vi-
vacity of the mind — for several days some diminution of appetite. |
The same symptoms after the other powder, which was taken a
week afterwards.
Second Proving ; Second Trituration.
The same prover. — Two powders of the 2d trituration were taken
as before.
12 m. About one hour after taking each powder he experienced
a sense of considerable weakness and much confusion in the head and
oppression over the eyes — continuing for several hours. He had no ap-
petite for dinner on that day, and for several days his appetite was con-
siderably less than usual.
Third Proving ; Third and Second Triturations.
Dr. J. C. Raymond. — 1851, Oct. 27th, 9 p.m. In usual health ; (pulse
75 per minute) a powder of Sulph. of Mercur., 3d trit.
Oct. 28th. Passed a wakeful and restless night; vivid dreams of
fires, exerting himself to extinguish them; viewing a person hung and
another cut up, seeing the blood and mangled remains. At half-past
282 Hfercurnis-sulphuricus.
8 a.m., experienced a violent beating in the left arm, commencing above
the elbow in the course of the brachial nerve and extending along the
radial nerve to the wrist, followed by paiii similar to that which is
produced by a blow received upon the arm below the insertion of the
deltoid muscle ; the pain affected, principally, the radial side of the
fore-arm, the thumb and index-finger; numbness of the fore-arm and
hand, also of the right hand ; icy coldness of the hands ; blueness of
the nails; frequent yawning, dulness and chilliness; creeping chills
ascending the back, when they reached the neck a general shudder
ensued ; pulse accelerated, counting 90. A dull pain in the forehead
followed the above symptoms, with burning in the face and ears and
slight febrile sensations.
Oct. 29th. Wakefulness after midnight ; dreams less troublesome
than the preceding night ; awoke in the morning, pain in the head under
the coronal suture, during the forenoon it was confined to the right
frontal region ; the pains were dull, extending deep into the brain and
were very unpleasant when exercising ; they passed off in the afternoon.
Observed no other symptoms.
Oct. 31st. 9 p.m. Took second powder, 3d trit. Sulph-merc.
Nov. 1st. "Wakefulness and dreams after midnight.
Nov. 2d. Chills from 12 m., to half past 1 p.m., with the same train
of symptoms as those on the 27th Oct., except the beating sensation in
the left arm. The pulse numbered 94.
Nov. 3d. Passed a restless night ; vivid dreams of fires ; the tongue
is thickly coated white, inclining to yellow at the base, the papillae are
enlarged and their red points project through the coating on the tongue ;
a pasty insipid taste in the mouth. Pulse 70.
Nov. 4th. Tongue cleaner than it was yesterday. Chills with
nausea from 10 a.m. to 2 p.m., with the same symptoms as those already
described on 27th of Oct. The restless nights continued with slight
chills on Nov. 6th.
Nov. 7th. Took a powder of 2d trit., 2 gr.
Nov. 8th. He recorded similar symptoms to those of Oct. 27th,
but they were more severe, and there was also pain and lameness of the
knees, noticed particularly when walking.
Nov. 9th. No symptoms.
Nov. 10th. Chills, slighter than those on the 8th.
Nov. 13th. Took 2d trit. ; chills followed every other day until the
20th, with a similarity of symptoms to those already described. While
taking the 3d trit. the urine was increased in quantity ; the stools were
softer and voided earlier in the morning than usual.
The 2d trit. produced hard, scanty and delayed stools. During the
whole proving there was violent itching of the hairy scalp.
Introduction to the Provings of Colocynthis. 283
13. — COLOCYNTHIS.
By Dr. Watzke, of Vienna/
COLOC. Colocynth, Cucumis, Colocynthis. Bitter apple. The
bitter Cucumber. Ger. Koloquinte. Fr. Coloquinte.
INTRODUCTION.
There are homoeopathic physicians who behold in the Hahnemannian
Materia Medica a masterpiece absolutely perfect and neither needing
nor admitting of improvements. Gross and Gouillon have quite recently
declared,f " that in its present state it is free from, faults and needs no
reformation? We regret that, in this respect, we are entirely of a
different opinion from our respected colleagues. We hold that science
has a right to demand this reform at our hands ; we see in it, the
highest desideratum of Homoeopathy, the fundamental principle of its
progress and development and the missing element, the obtaining of
which will secure the scientific appreciation of our opponents.
While we thus openly, in the face of friends and foes, acknowledge
our pharmacognostic deficiencies, we desire in the most earnest manner
to deprecate the supposition that we undervalue or mistrust the provings
of Hahnemann. We call in question neither the conscientiousness, the
earnest truthfulness, the comprehensiveness, and the acumen of the
observer, nor the accuracy of the experiments themselves ; on the
contrary, we are deeply convinced that nothing will conduce to place the
merit of Hahnemann upon a loftier basis and to set his genius and
observing power in a stronger light, than those very subsequent provings
which must furnish the materials for a physiological construction of our
Materia Medica.
It is high time we began to be ashamed of stretching our indolent
limbs, and lolling lazily upon the couch prepared for us by the
* This valuable essay, from the pen of Dr. Watzke, of Vienna, is the first of
the reprovings undertaken by the Austrian Association which was published. It
appeared in the first number of the " Oesterreichische Zeitschrift fur Homceo-
p-ithie," from which we have translated it in full. An abridgement of it was
published by Dr. Irvine, of Leeds, in the Appendix to the " British Journal of
Homoeopathy" but we have thought that the entire production would be an
acceptable addition to our literature. — Ed.
•fr Allg. horn. Zeit. 25, Mo. 7. Arch, fur hom. Heilk. 20. Heft 3, § 1.
284 Golocynthis.
laborious toil of the Master ; let us muster up courage to tread bravely
in his foot-steps, and pursue, with untiring patience, the path he has
opened up to us. If, like him, Ave will devote half a life to the
proving of drugs ; if, with the same tireless zeal, industry and self-
sacrifice, we will continue to experiment as he did, we shall soon become
aware of the infinite affluence of observation and experience, the colossal
piles of the most careful experiments which constitute the immovable
basis of such provings as those of nux vomica, belladonna, pulsatilla,
bryonia, aconite, rhus, and mercury ; we shall then see the reason why
those collections of symptoms, which to others seemed like chaotic
fragments, or hieroglyphical mysteries, presented to Hahnemann, of
necessity, a physiological picture of the greatest symmetry and order,
and simply because he was himself the experimenter, or at least the
exclusive director of the trials.
What is it then that calls for revision and reform in a work which
we thus laud to the skies ? t
The necessity of a revision of our Materia Meclica has reference
less to its matter than its form. So far as we are concerned, it rests
upon the fact, that the materials of our provings have been transmitted
to us not in any natural, physiological order, but solely and exclusively
as an artificial fragmentary index. The master-builder was mistaken
in supposing that his disciples, who made incomplete experiments, or
none at all, would inherit his own wisdom, and in thinking that those
who were not familiar with the whole, would nevertheless, like himself,
have a perfect conception of the value and significance of the separate
parts.
The unfortunate schema, in which Hahnemann has delivered to us
his results, leaves us in entire ignorance as to the mode and manner in
which his experiments were made. He has given us simply the
answers to the problem ; he should also have shown zcs the pirocess by
which the answers were obtained*
We are entirely ignorant whether the symptom which is followed by
this or that name, was the result of one or several experiments; nay,
we do not even know that the same name always indicates that the
symptom was observed in the same individual.f We are seldom in-
* We may seriously entertain a doubt as to the justice of this reproach
against Hahnemann When we reflect upon the entire novelty of his results, upon
their absolute rejection by the world of science, and more than all upon their
great bulk and upon the fact, if we may believe the tradition, that their publica-
tion at all, was due to the gratitude of a patient, we may well excuse the
intelligent caution that submitted the results in an accessible shape without the
monstrous burden of the literal provings. The original manuscrip s, however,
from which the Materia Meriica Para was compiled, are understood to be in
existence ; and now that Homoeopathy numbers her priests by thousands, and
her votaries by the million, no more acceptable offering could be made than
the literal reproduction of the original provings of Hahnemann and his dis-
ciples.-J. W.M.
+ The name in question is sometimes used generically; thus, Gross, Slapf
and others affixed their own names to all the symptoms which they had col-
lected from perhaps half a dozen provers. — Watzke.
Introduction to the Proving s of Golocynthis. 285
formed of the size of the dose, or its form, or of the time and frequency
of its administration. We consequently generally learn as little of the
development, duration, course and termination of the drug-sickness, as
of the appearance and disappearance of the individual symptoms. We
have no means of discriminating between transitory and accidental
phenomena, and those which are necessary and essential. We remain
wholly, or almost wholly uncertain as to the centre and periphery of
drug-action and its primary or secondary effects, as to its sympathies,
synergies and antagonisms, and the extent and importance of the
medicinal disease. We are kept in ignorance of the relation of the
symptoms to the predisposing and occasional (medicinal) causes, and
get no glimpse of the degree of intensity with which the drug acts upon
the healthy organism in general, and upon individual systems and
organs in particular.
We have called Hahnemann's schema " unfortunate," because, instead
of presenting us with a clear picture of drug-diseases, it gives us only
a monstrous agglomeration of symptoms, directed more to the memory
than to the understanding ; because it not only greatly increases the
difficulties of acquiring a knowledge of the Materia Medica and the
employment of the homoeopathic practice by his disciples, but throws
an almost insurmountable obstacle in the way of the conversion of
sceptical physicians of other schools, and most unfortunate of all,
not unfrequently deters the most energetic minds from its study, thus
depriving the new school of the assistance of those best calculated to
become its leaders and chief supports.
We give this free utterance to our sentiments, in the firm conviction
that they are shared by the great majority of our colleagues, and that
the work of reformation, which we have thus courageously begun, will
find sympathy and support from many quarters. The noble example of
Hahnemann shows what may be accomplished by one powerful will ; and
though we have set the physiological construction of his Materia Medica
before us as our life-long task, still we are not guilty of the ridiculous
presumption of supposing that we have the herculean arms that can
singly bring the gigantic undertaking to a successful completion. As
regards the reprovings, the most laborious part of the work, we are
already surrounded by no inconsiderable number of zealous, able and
sympathising friends.
May we succeed in so accomplishing our object, that our exertions
shall prove of lasting service, not to a system, but to science — not to
the parlizans of Homoeopathy or Allopathy, but to the practical phy-
sician, and shall serve as a lasting proof that the advancement and
perfection of specific phakmakodynamics, and the improvement of
practical therapeutics are essentially identical!
286 Colocynthis.
CHAPTER I.
Names, Description, and Chemical Composition of Colocynth.
There is uncertainty enough in the nomenclature of Colocynth.
Lobel and Bauhin long since complained of this difficulty, and in
spite of all the efforts of the philologists, the derivation and original
meaning of the word remain to this day a mystery.* The number of
synonymes used by botanists and physicians is so enormous, that the
reader is frequently left in doubt, especially among the writers of the
middle ages, as to what name conceals the author's reference to
Colocynth.
Dioscorides and Galen called it simply KoXoxjvdic' — the diminu-
tive of xoXoxjvfi't), here at once indicating contempt and its inappro-
priateness as food. Hence some have derived it from xo'Xov, xCw, quasi,
dogs' food ! Scribonius Largus and Bauhin translate it Citcurbitula,
a little gourd. The xoXoxjv^ kiyotf, which Dioscorides considers as
a synonyme of Colocynth with the barbarian Thymbre, Anloyenes, and
Tutastra, according to Cornarius, and others, means xoXoxjvStj
a^iorf ; there is, therefore, no Cucurbita caprina. Hippocrates and
Scribonius Largus write, according to Fcesius (tautologicallv),
xoXoxuvSitf aygia, and not as Schulze and others, xoXoxvvSr] ky^a. The
latter is not at all the true, legitimate Colocynth, but one of the similar
varieties of Gourds with hard, woody, pear-shaped fruit (low German,
Regelsbeeren, Gichtbeeren) and juicy pulp, difficult to dry — the Colo-
cynthis -Germanica, Colocynthis altera, Trag. ; Colocynthis pyriformis,
Lobel. ; Colocynthis fcemina, Dodon. ; Pseudocolocynthis pyrifor-
* Martinius and Lemery derive it from the Greek : #a£«, ryv xoiX/av
6u tov xuKov xjvsiv, xvrfisw, xjeiv ; quod ventrem, ahum, inteslina moveat
atterat,turbat; Duvergie and Ratier repeat the derivation with a little modi-
fication ; Kraus does the same, and writes it " Koloquynthe" ; while Schulze
makes himself merry over it. It is probable, according to Kaltechmidt's Com-
parative Dictionary, that Colocynth, the Portuguese Calabas, the Spanish Calabaza
the later Latin Calebassus, the Arabic Charaba, as well as Cucurbita Cu-
cumer, ayyovpov, Gurke, Kurbis, Cucumber, Gourd, are all derived from the
same, still undiscovered, Sanscrit root.
The worst of the matter is, that the learned are not agreed as to what was
meant among the Greeks by xoXoxjvo?]. Bauhin thinks it included the round
fruits in our present family of Cucurbitacea ; while those which were lono-ish
were called in different provinces (fu'jy), tfixuuvr), tfixuwvia, and most commonly
tfixiios". Marcellus again maintains exactly the reverse of this. Dierbacii
holds the antiquarian exegesis of the Cucurbitaceae to be a very difficult matter
and translates xoXoxuvSr] by " Gurke" (Cucumber, Gherkin) ; Grimm does the
same, while Passow renders it by " Kiirbis" (Gourd, Pumpkin). (Grimm's
Hippoc, B. 2, § 138).— Watzke.
Names, Description, etc., of Colocynth. 287
mis, Eyst. ; Cucurbita vulgaris, canina, sylvestris, barbara, marina,
aliorum ; tfofjwpotf Plinii.*
Whether Hippocrates always intends the Colocynth by rfixuwv*]
(Cucumerulus, Banh.) is by no means as certain as Galen takes it;
for, according to Dodon/eus (Stirp. hist. V. 2, 7), the expression is as
often used to denote the Elaterium dixvog aygiog, Cucumer sylvestris.
That the " uncut, small, round gourds tfi'xurj ixr^rog twv /xix^wv xm
ifrgoyyvXCiv," which Hippocrates (De Coxend.) prescribes in enemata
against Coxalgia from taking cold, is (according to Dierbach) the
Elaterium, and not our Colocynth (as Galen thinks it is) becomes
extremely probable from the fact that Hippocrates (irsgi yw. yvg.
and irsgi gVixuTjg) prescribes the finely triturated pulp of the xoXoxuvistg
aygia kneaded with honey, together with tfixunjs ews£i«v»] (Cucumer is
agrestis medulla) as an anal suppository for purging the bile, and as
a vaginal application in cases inclined to abort, and recommends the
injection of an infusion of the same in wine and milk into the vagina
in, uterine ulceration.
Among other Greek authorities, Colocynth is known as cfixua irixgu •
among the Arabians as Chandcl, Kandel, Haanthal, JFIandal, and
(with the article) Alhandal. Tragus heads his chapter on Colocynth
with the caption " Colocynthis vera 11 ; Lobelius with " Cucurbilula
amara cathartica"; Dodon/eus calls it Colocynthis prima, Colocyn-
this mas, and Anguria sylvestris; others again, Cucurbita deserti,
Cucurbita Alexandrina, Cucurbita Prophetai Eliscei, Melo agrestis.
The medical poets bestowed upon it the fanciful titles of sal and fel
terrce, nex, peslis plantarum, mors in olla.\
Botanically, the Colocynth is known as Cucumis Colocynthis
(Mon&tia, Monadelphia Linn.), Citrullus Colocynthis and Colo-
cynthis officinalis (Schrader), and is related to the water-melon
(Citrullus vulgaris) — the bitterest and one of the pleasantest of
fruits ! It is an annual plant, with a thick fleshy root, stem herba-
ceous, procumbent, clinging to neighboring objects by means of
numerous filiform tendrils, fleshy, fragile, angular, branched, hispid;
leaves alternate, ovate, pointed, five or more lobed, clothed on both sides
with short, blunt, somewhat recurved hairs ; flowers axillary, solitary,
stalked, monophyllous, campanulate, yellow.
It grows wild at the Cape of Good Hope, in Japan, Arabia, Nubia,.
Syria, Asia Minor, Cyprus, in the islands of the iEgean Sea, and in
Southern Spain.
* These latter appellations are found also among the synonymes of the Elate-
rium and Bryonia! Hardouin corrects tfo|A(po£ into (ftfoyyog. — Watzke.
t The young man of Elisha (2 Kings, c. iv. v. 38,) evidently not a very
skilful botanist, in the time of the dearth gathered his lapful of wild gourds, and
shred them into the pot of pottage preparing for the sons of the prophets. But
while they were eating, they perceived the bitter taste, and cried out " O thou man
of God, there is death in the pot !" These gourds were probably not Colocynth-
apples, but the fruit of the Cucumis Praphetarum, which grows abundantly in
Palestine, and greatly resembles the common gourd (Oken's Naturgeschichte
3, 827).— Watzke.
V
288 ColocyntJiis.
The only part hitherto used in medicine almost without exception is
the fruit — pepones, fructus, poma colocynthidis — (Ger ?)Koloquinten — ,
Purgier-, Purgierparadies apfel — ; (Holl.) Quintappel ; (Eng.) Bitter
apple. They are globose, first green, then yellow, as large as an orange, and
are covered by a smooth leathery rind destitute of hair. The fruit
comes to us dried and deprived of its outer rind, and is covered with a
thin, whitish-yellow skin which contains a very light, spongy, white,
dry pulp (pulpa colocynthidis, (frKvuvyg (f-rroyyog (Hipp.) xokoxwdiSog ro
svtov (Gal.) Colocy nth-pulp), containing numerous ovoid, hard, smooth,
yellowish-white seeds, and having an extremely bitter, acrid, repulsive
taste and a sweetish, nauseous smell The moderate-sized, externally
full, perfectly dry specimens are the best.* The well-washed seeds are
tasteless, the skin is mucilaginous, the kernel oily.
Meisner, Vauquelin and Braconnot have given us analyses of the
Colocynth pulp.
Meisner.
Braconnot.
Bitter matter (Colocynthin)
14.4
Bitter matter (Colocynthin)
Extractive ....
10.
with some resin
41.4
Bitter fixed oil .
4.2
Azotic matter
21.4
Resin insoluble in ether
13.2
Resin ....
4.3
Gum .....
9.5
Bassorin . .
3.
Deliquescent salt of potash
Gummy extract
17.
not soluble in alcohol
7.1
Vegetable jelly .
0.6
Vegetable jelly .
18.6
Phosphate of lime and magnesia
5.7
Acetate of potash
5.7
Ligneous fibre .
19.2
Water ....
5.
Colocynth Pulp
101.8
Watery Extract of Colocynth
98.5
Vauquelin found in the Colocynth pulp a peculiar principle, Colo-
cynthin ; besides this he found oily matter, extractive, resin insoluble
in ether, gum and various salts. The watery extract of Colocynth is a
yellowish viscous liquid, which foams when shaken, like a solution of
gum, and does not pass through filtering paper. Murray says that
the alcoholic tincture will not filter, but we have not found this true
with our tincture and our filtering paper.
CHAPTER II.
Ante-Hahnemannian medicinal Employment of Colocynth.
This remedy is as ancient as medicine itself; it was known to Hip-
pocrates, Dioscorides, Galen and Pliny, was highly esteemed and
frequently employed by the Arabians and the physicians of the middle
* The Arabian caution never to employ in medicine a Colocynth apple which
was the so'itary fruit upon the plant, is in more than one respect ridiculous.
Mesue and Avicenna have also male and female Colocynth-inannikins ! — Watzke.
Ante-Uahnemannian Employment of Colocynth. 289
ages, slighted by the moderns, and latterly consigned to the great
lumber-room of obsolete drugs, — the medicinal Hopital des Invalkles !
Some of the old Latins speak of it with as much enthusiasm and seem
to have relied upon it with as much faith as you will find among the
fashionable adherents of Sal-ammoniac, Iodine, Calomel, and* the
other remedies in vogue in our own day. Ettmuller declares that it
formed with scammony and helleborus niger, a triumvirate that was
capable of doing wonders !* It was frequently esteemed the ancora
sacra in obstinate, long-standing cases which had even resisted the
efficacy of Agar icus and Turpeth mineral, a fact of no small significance.
It seems to have been most in use among the Arabians. They re-
commended it in a great number of the most various affections of the
brain, nerves, muscles, joints, lungs, thorax, kidneys and bladder;
against chronic headache, obstinate hemicrania, chronic vertigo, weak-
ened mental faculties, melancholy, apoplexy, epilepsy, delirium, para-
lyses, chronic spasms, articular pains, rheuma, podagra, lachrymation,
angina pectoris, asthma, chronic coughs, dropsy, but above all in
coxalgia,f and mucous and flatulent colics. They administered the
finely pulverized Colocynth as a snuff for jaundice, decoction of the
pulp in clysters for colics ; the fresh juice of the leaves as a salve for
the itch and cutaneous eruptions ; the green leaves themselves as a
poultice to discuss or mature swollen glands, boils and abscesses. They
used a decoction of the root as a specific against the bites of serpents
and scorpion stings.J The oil was used against dandriff and the falling
off of the hair ; they dropped it into the ear to remove noises, rubbed
it into the bellies of worm patients, filled aching decayed teeth with
cotton moistened with it, fumigated other dental affections with the
kernel of the seed, fastened loose teeth by bathing the mouth with
Colocynth-vinegar, applied the ashes of the burnt rind to the painful
anus, and sprinkled dwellings with a decoction of the drug to extermi-
nate or keep away fleas and other vermin. {Joan. Mesuw op. Ven. 1589.
He simpl. c. IV. Avicennai, Arabum med. principis Canon med.
Ven. 1608, lib. II, c. 130).
This pretty nearly exhausts the therapeutical applications of Colocynth
previous to Hahnemann. Very little of it is the exclusive production
of Arabian genius ; it was mostly derived from their Greek and Roman
models and predecessors.
We have already stated that Hippocrates used it, and in what cases.
Dxoscorides§ prescribes it in Coxalgia (frictions with the fresh juice),
* Alas ! that in so potent a triumvirate we should be left in ignorance which
was the real wonder-worker. — Watzke.
t Rhazes cured many thousand ischialgias by means of Enemata of Colocynth
and Saltpetre. Notwithstanding, he recommends a legion of other remedies in
that affection ! (Ejusd. op. pare. Fere. 1510. De sciatica passione.) — Watzke.
X Rhazes cured his own son with the decoction of the root when he had been
stung by a scorpion in four places (Bauhini, Hist, plant, univ. Yvcrd. 1561,
torn. Jl, lib. II.) — Watzke.
§ Comment, in Diosc. Ed. Kiihn, p. II. c. 161. Fernel too found frictions of
the fresh juice very beneficial in Coxalgia. Pliny recommends, also, friction
with the oil. — Watzke.
290 Colocynthis.
in paralyses, colics and toothache ; Scribonius Largus (De Compos.
Med. Par. 1528, §99) in lumbago, epilepsy and arnenorrhcea.
Archigenes (Oribasii collect, lib. VIII. Ven. 1558, c. 46) con-
sidered it an excellent purge for feverish patients, token the fever was
mild and favorable, and came on with headache, great zveakness, and
terrible pains in the hip. He administered it as a sort of oleo- watery
infuso-decoction in combination with veratrum and scammony. Paulus
.ZEgineta (Ejusdem opus divinum de rented. Basil. 1532, p. 374)
considers it as rather a nervous than a sanguineous purgative (!) He
esteems it highly in headaches, depending upon an affection of the
dura-mater, or of the scalp ; in vertigo, hemicrania, epilepsy, apoplexy,
trismus, chronic lachrymation, asthma, chronic cough, arthritic affections
of the kidneys and bladder. In coxalgia he rubs in the fresh juice (in
op. c. p. 425). Pliny (Hist. Nat., torn. II., lib. XX. c. 3) and
Johannes Activarius (Ejusdem methodi med., Ven. 1554, lib. IV. p.
215) recommend it in nearly the same affections. Besides this, they
both recommend it highly in jaundice ; the latter would have it used with
great caution, but adds, nevertheless, " Dantur autem scrupuli duo /"
Colocynth and Agaricus were the principal ingredients in the famous
Hiera Pacini Antiochii (Hiera diacolocynthidos, Siarfixvuvys) a secret
remedy employed by the greatest physicians of antiquity : Appolonius,
Asclepiades, Andromachos, Ti emison and Kurus Ephesius, against
the most severe and procrastinated disorders, podagra, gout, paralyses,
epilepsies, tetanus, aphonia, cancer, &c* (Schulze.)
Nothing new has been developed in relation to the use of Colocynth
by the great majority of medical writers since the days of Greece and
Rome, those of the most modern times not excepted. It only plays the
same part as a component of still more piebald, still more wonderful
mixtures.
It owes to Paracelsus the honor of having been admitted into the
company of jalap, scammony, and rhubarb in the famous Extractum
Catholicum (Schuhe, diss, de Coloc. Halce, 1734), which was, as
its name imports, a panacea, f Bonetus and TiM.a:us (Casus med.
* This Hiera was a precious composition, a dram of which contained two and
a quarter grains of Colocynth. Piulenides, of Kataua, transcribed it on his
death-bed, and sent it to the Emperor Tiberius. Scribonius Largus says of the
discoverer of this sacred mixture, which he extols to the skies : Hierce, i. e. sacra
covfedionis 7wmen, ei propter duas causas tribuit ; unitm, ne ejusverum nomen
dicendo ostenderet, qua csset ; altcrum, quo magis sub hoc vcnerabili nominis
specie commendaret medicamentinn.
We cannot refrain from adding the following expression of Scribonius Largus
on the subject of the Hiera : Illud vero (says he, Op. cit. § 103) supra omnium
opinionem est, quod ad stomuchicos evidenter convenit, quam sit virosissinum
viedicamentum advprsus stvmachum. Had he only been able to draw a corollary
from this proposition ! He contented himself, however, in pretty much the same
fashion as our opponents do at the present day : " Sed videlicet in cjusmodi rebus,
potentior usus raiionc est.' 1 '' — Watzke.
f The receipt of the Catholic extract was, however, not a stereotype • it under-
went various changes and combinations, depending upon the author who pre-
scribed arid the ditnase against which it was used. Triller substituted aloes and
hellebore in place of rhubarb; Hoffman, gamboge and fores Martis ; Potter
Ante-Hahnemanniwi Employment of Colocyntli. 291
et. obs. 1667, lib. IV, cas. 9 et. 34, et in Epist. lib. Ill, Epist. 40,)
recommend Colocyntli in menstrual difficulties, especially in deficient
catamenia, in suppressed lochia and for the expulsion of a false conception
or dead child ; the former prescribes it as a uterine suppository, the latter
in decoction sub forma suffitus, insessus aut injectionis* Dodon^eus
(Stirp. lust. Ill, 2, 26) employed it especially in apoplexy, chronic
vertigo, hemicrania, deafness and violent colic. He says, also, that Colo-
cyntli was used in conjunction with aloes and myrrh for the purpose of
embalming. Bayrus and Schenk (Obs. med. Franco/. 1665, p. 424)
dre> teeth by means of it without pain and without an instrument.f Tragus
{Stirp. Germ. Arc/. 1552, c. 97) found it useful in colics, putrid fever
and particularly in dropsy; Lobelius (Stirp. adv. nov. Lond. 1570 in
cap. de coloc), in apoplexy and coma, administered in clysters containing
from a scruple to a dram ; Ettmuller ( Op. med. Gen. 1736, torn I, p.
758) in intcrmittents,J mucous colic and epilepsy. It figures among
the chief constituents in the drastic mixtures which Sydenham em-
ployed almost exclusively in the treatment of dropsies (Op. omn. med.
Pat. 1725, p. 565). Riverius (Op. med. univ. Ven. 1687, t. II. p.
198) praises it as an excellent purger of the brain (ad cerebrum
potenter expurgandum) in all diseases not inflammatory. Sennert
(Inst. med. Vittenb. 1644, p. 958) used it in podagra, asthma, colic
and chronic rheuma. Van Helmont considers it the best anti-syphili-
ticum.§ It was also used against Syphilis by Zacutus Lusitanus
(Prax. med. admir. Lugd. 1667, t. II, p. 93) and Bonetus (Thesaur.
med. pr. Gen. 1694, t. Ill, p. 309). For greater certainty, the
latter used it in a diaphoretic decoction with mercury. He also destroyed
worms in the ear with the decoctoin of colocynth (in op. cit, p. 1004).
Zacutus also found the external application of the colocynth oil of
great service in nervous pains and diseases arising from cold and
dropping it in the ear, in pain and ringing in the ears.| He also says
myrrh, crocus and senna. In hypochondria it was prepared with castor, in renal
affections with amber, and in loss of fluids with mcrc-dulc, &o. — Walzke.
* Bonetus altogether condemns Colocynthine pessaries in absence or deficiency
of labor pains ; although they hasten the labor, there is risk of killing both mother
and child. — Watzke.
t They scarified the gum for this purpose ; caused the patient to hold a decoction
of Colocynth in vinegar, in his mouth, and then seizing the tooth with the fingers,
extracted it at once with ease and without the slightest pain ! — Watzke.
I It formerly possessed sympathetic therapeutic virtues in intermittent fever.
" Mirum dictu," says Pliny op. cit, " colocynthidis semina, si fuerint pari numero
adalligata, fcbres sanirc dicuntur, quas Graeci periodicas vacant. — Watzke.
§ Half a colocynth-apple was macerated over-night in a well stopped flask of
wine, and the wine was drunk in the morning. This was repeated five or six
times, and the patient kept at home fasting. (Ettmuller, op. cit.)
Sylvius de la. Boe (Prax. med. pp. Lugd. 1761, art 257,) declares colocynth
to be the most admirable antidote to syphilis. Hornemann tells us that the inhabi-
tants of Fez know no other remedy for Syphilis than salt and colocynth. and that
they succeed in curing cases which are not inveterate (Tagebuch ciner Reise nach
murjat, &c, Wien. 1802, §§ 89, 102).— Watzke.
|J The oil was prepared by filling an excavated colocynth apple with oil and then
roasting it in hot ashes. — Watzke.
292 Golocynthis.
that when rubbed into the head, it prevents the hair from turning gray
and colors it black. Juncker (Consp. med. Hal. 1734, p. 216,)
prescribed colocynth in phlegmatic constitutions for asthmatic parox-
ysms, suppressed haemorrhoids and obstinate toothache. Crantz has
seen good results from its employment in lethargy and serous apoplexy ;
Kartheuser (Fund. nat. med. Franco/, 1*767, t. I, p. 600) in obsti-
nate diseases of the mucous membranes. Lieutaud (St/ii. pr. med.
Amst. 1765, p. 655,) rubbed a mixture of the pulp with ox-gall into
the abdomen of verminous patients.* Dahlberg praises the admi-
rable effects of colocynth in gout (cum fermite venereo), especially in
that of the head and. hip, in intolerable pains from the abuse of
mercury, as well as in paralysis and algid fevers. Fabre cured a severe
affection resulting from suppressed gonorrhoea with colocynth
{Murray, app. med. 1. 1, p. 583). Colombier (Code de mod. milit. I.
5, p. 420,) relates that many soldiers cured themselves of gonorrhoea in
a few days by eating a whole colocynth apple in one or two doses.
Among the moderns, Vogt (Pharmakod, B. 2, Abth. 1, S. 318),
Richter (Arzneim. B. 2, and spec. Th. B. 7, § 511, and B. 3, S. 336),
and Burdach (Arzneim B. 3), have labored on the therapeutic chapter
of Colocynth. They recommend it in paralyses (especially of the
lower limbs, bladder and rectum) ; in mental affections (lunacy, mania,
melancholy and imbecility) arising from atony of the ganglionic sys-
tem ; in chronic spasms and other nervous disorders (epilepsy, vertigo,
coma, nervous headache) ; in hypochondria, jaundice, intermittents,
menostasia, and chlorosis, from congestions and obstructions in the portal
circulation, liver and spleen, as well as in the lymphatics and glands,
from mucous accumulations in the digestive organs, suppressed haemorr-
hoids, &c. These recommendations are not derived from their ex-
perience at the bed-side, but have for the most part a purely ideal
origin ; and even the illustrations drawn from the practice of cotempo-
raries have generally the air of being only pathological reminiscences
from the days of the Arabians. We add these latter, and append to
them such memorabilia concerning the drug as we have been able to
find in modern times.
Bang found the decoction of Colocynth the best remedy against
dropsy, the simple result of serous effusion. Kranner also employed
the decoction with success in dropsy. Hufeland considered it the
most powerful diuretic for heavy, sluggish constitutions. Wrisbach
(Kleinerfs Rep., 4 J. 11, 85) had occasionally excellent effects in the
dropsy of brandy drinkers, accompanied by disorganization of the liver,
stomach and spleen. Schlesier lauds his piluloe hydrogogce (coloc,
gamb. and croton oil) against the same affections. Duhrsen (Kleinerfs
Rep., 1836, 2, 62) employed colocynth with great advantage in chronic
ascites following scarlatina. Buchhave found it efficacious in hydro-
thorax. Hillier wrote a treatise, which we have unfortunately not
been able to find, on the use of Colocynth in dropsies (Leip. 1821).
* Murray (op. cit.) does not consider colocynth. as a specific against worms.
Lumbrici did not die in a saturated infusion nnder from fouitien to twenty-four
hours. — Watzke.
Decline and Fall of Colocynih. 293
Heim employed the tincture externally as a powerful discutient in
cases of herpes (with Timt. Ant. sapon) and in scrofulous swelling of
the glands (with castor oil). Conradi employs it (with oil and
opium) in large inveterate hernias, in which the faeces collect and give
rise to obstructions. Berends found frictions with the tincture or the
application of a Colocynth plaster, useful in cases of obstruction from
accumulated faeces (Kleinert's Eep., 1836, 10, 169). Schmdhr res-
tored a man of 70 from a gastric apoplexy, after leeches, emetics r
irritating enemata and foot-baths ; not only was the principal trouble
relieved, but also the previous sleeplessness, obstinate constipation and;
imperfect paralysis of the upper eyelids and tongue. Neumann thinks
he has cured paralyses of the upper and lower extremities of the colon,
ccecum and rectum in scrofulous individuals. This drug alone re-
lieved a paralysis of the masticatory muscles and eyelids after an attack
of gout, and another of the thigh after a violent attack of hemorrhoids *
CHAPTEK III.
Decline and Fall of Colocynih.
Notwithstanding the extended list of authors, both ancient and
modern, who have treated on the efhployment of Colocynth, it has
long since lost its high position in the learned treatises of the Phar-
macopseists. Its fall began with the insinuation, that it was a heroic
remedy full of danger, and the administration of which demanded
mature deliberation ; that it should only be used in rare cases of the
severest forms of chronic diseases ; f a drug the artistic employment of
which could only be learned from the greatest masters of therapeutics
(Geoffrey, Mat. Med. Venet. 1742, Art. Coloc). Some counselled, on
this account, that its use should be limited to older physicians, the
younger being forbidden to prescribe it.J
At the present time, when we all have such unbounded faith in
* We are far from supposing that we have thus presented a perfect picture of
the allopathic therapeutic employment of Colocynth. Such was neither our inten-
tion, nor would it be of essentjal service if done. We must confess that when we
compare the time and labor which we have expended in turning over some half
hundred old folios and qnartos, and more modern Journals and Repertories, with
the advantage gained, we are somewhat at a loss whether to be proud or ashamed
of the foregoing chapter. — Watzke.
t Trtller (Thesaur. Med. Franc. 1774, p. II, p. 203) calls Colocynth « in-
famium medicaminum exemplar, remedium triste, ingratum, suspectum, du-
bium, violenlum, imo pane virulentum, atque hinc mcrilo proscribendum ex
offi-tinis." C. Hoffman, on the other hand, declares it to be to severe diseases
what a big wedge is to a big log. Lions are not to be caught in mouse-traps, and
many a chronic malady is suffered to go uncured because the physician is afraid
of his drugs (Geoffroy). — Watzke.
X From this it is easy to see that the older physicians of those times understood
the secrets of medical tactics as well as their compeers of the present day. The
only thing we could wish i3 that the legal age at which colocynth might have
been prescribed had been stated in the diploma ! — Watzke.
294 Colocynthis.
counter-irritation we are less afraid of colocynth than formerly ; but,
inasmuch as it has been thoroughly settled that there is no such thing
as a specific, we no longer, of course, consider colocynth as such, but
allow it to share its virtues with at least ten other drugs (drastic sub-
stitutives) ! the necessary consequence of which is, that people have
become indifferent to a remedy whose place is so easily supplied. So
far has this gone that our venerated instructor Hartmann ranks colo-
cynth among the remedia super flua, ! and the hypothetical indications
given by Vogt, Richter and Burdach for the therapeutical use of
Colocynth are of such a character that they will answer equally well
for more than half a dozen of its pharmacological neighbors.*
This indifference of the moderns and the horror of the ancients have
<their origin in the same causes, the immoderately large, often absolutely
poisonous doses in which the drug was administered, and especially in
the dim notions they had of its action upon the healthy organism.
They had learned, to be sure, from accidental cases of poisoning, that
" it set the stomach, bowels, and whole body in an uproar, produced
the most dreadful pains, corroded the intestines, excited hemorrhages
from the anus," <fcc. (Geoffroy op. cit.) but this was only the dark side
of the physiological picture. The medical world, with a full knowledge
of the no less poisonous properties of aloes, jalap, barytes, calomel and
iodine, continues to dispense them with a liberal hand, but has only
eyes for the deadly qualities of colocynth. f
It is wonderful what combinations of drugs have been excogitated
to tame the wild and savage fierceness of colocynth. One of the most
common favorites was sulphuric acid ; Ettmuller on the contrary (op.
cit.) considers the alkalies as the best, corrigens, declaring : Ac.ida enim
castrant, non corrigunt coiocynthidem. Hoffmann (Op. omn. torn. I,
pars II, c. 5) thinks the same of the decoction. Others subjected it
to a fermenting or rotting process. Wedel (Exercit. med. phil. XVIII)
and Neumann (in Prcelect. chymico-pharm. p. 797) have observed
that the pernicious principle of Colocynth only derived new power
from fermentation with must so highly recommended by Boulduccius
(in Comment, she. sclent. Paris, 1701). Mucilaginous and aromatic
remedies were considered by many as the best corrigentia ; it was
commonly combined with mint, balm, myrrh, and the like, when pre-
scribed as an emmenagogue. The Arabian physicians frequently made
use of astringents for this purpose, but Mercurialis and Rolfink
condemn this method of correction altogether. The violence of pur-
* Mesue the younger says that nothing should deter one from using a remedy,
which, like colocynth, could not be replaced by any other. Now-a-days how-
ever, Colocynth, too, has its surrogate. The entire periodical literature of the
Hippocratic school for the last ten years cannot probably produce ten instances of
the successful therapeutical employment of Colocynth. — Walzke.
t However true these remarks may be in relation to Germany, they do not ap-
ply with equal force to England and America, where colocynth has for a number
of years been quite t, fashionable component in pills and extracts for the regula-
tion of the bowels. Morrison's " Hygeian pills " were said to have contained it
—J. W. M.
Decline and Fall of Colocynth. 295
gatives was only increased by the addition of bdellium aud mastic,
and Colocynth acquired in this way a vis furiosa. Urine had its
advocates as the best softener of the violence of Colocynth ; Rivekius
(Prax. med.^ univ. Venet. 1687, torn. II, p. 198) and Freitag say that
the urinary infusion not only loses all its bitterness and becomes taste-
less, but parts with so much of its poisonous essence that it can be
administered by the dram. Others, more refined, objected to this vehicle
as not exactly aesthetic, and substituted the sp. roris majalis. Others
still macerated it in whey, water or wine ; many corrected it with simple
olive oil, but the most followed the example of Dodon^eus, who main-
tained that colocynth could only be corrected by other violent pur-
gatives.* Not a soul seems to have fallen upon the best and surest
corrigens — smaller and less frequent doses ! This seems to have been
the egg of Columbus which Hahnemann succeeded in standing on end
by the introduction of little doses.
To the apparently instinctive recognition of the necessity of dimin-
ishing the effect of the excessive quantities of colocynth administered
by the cotemporaneous exhibition of its antidotes, poor suffering
human nature owes a variety of the most ingenious formulae. We have
already referred to the Hiera of Pachius Antiochius and the catholic
extract. The following were not less celebrated weapons in the hands
of the great masters of Therapeutics.
1. Piluloc de duobus. — Equal parts of scammony and colocynth
with q. s. of essence of cloves. This was often used by Sydenham and
other English physicians ; Freind thinks he has used it successfully in
confluent small-pox ! (Comment, de febr. ad Hippoc. c. VIII, p. 206.)
2. Pilulcc Cochiai.\ The cerebral pills of Nicolai and Almansor
contained, besides colocynth, aloes, scammony, absinthium, mastic, &c,
and were the most approved remedy against hemicrania.
3. Pilula? trium Diabolorum. The three-devil pills were composed
of Trohisc-Alhand., Diacryd aa. gr. IV. Merc. dale. gr. VIII. ; M.
ft. pil No. 4, pro dosi — a notorious clap-specific !
4. Pilula; iliaccc of Rhazes. Colocynth 10, Scammony 3, Saga-
penum 10. Dodon^eus thinks it the pleasantest and mildest laxative
(Stirp. histor. Ill, 2, 26) ; Rolfink (De purg. veget. tab. p. 149)
considers it one of Paracelsus' many hobbies.
5. Confectio Hamech. According to Schulze, a disgusting, ungrate-
ful compound of purgatives, with a basis of colocynth, which was used
* Paradoxical as this assertion may appear, it is still not entirely destitute of
foundation. The older physicians had doubtless already had some intimations of the
mutual antidotal relations of purgatives. Celsus says (Lib. II, c. 12), "Medica-
menta stomachum fere Icedunt, ideoque omnibus catharticis Aloe miscenda est."
Dodonjeus entirely rejects the Trochisci Alhandal formed of colocynth-pulp
finely triturated with trigacanth, which, apart from the excessive doses (from six
grains to two and four scruples), was, next to the tincture, the best, simplest, and
most effective form in which the drug was commonly administered. — Watzke.
+ Cochos, i. e. Caput, says an old commentator upon Rhazes (Op. parv. Ven.
1510). We do not find cochos, however, either in the Greek or Latin lexicon :
it may perhaps be tautological— ra xoJocia, grana rotunda, pilula. — Watzke.
296 Colocynthis.
against psora, lepra, cancer, elephantiasis, tinea, old ulcers, and chronic
gonorrhoea.*
6. Extractum panchymagogum Crollii et Hartmanni. This was
composed of colocynth, mild mercury and many other (drastic) reme-
dies, and was employed in syphilis and in the beginning of malignant
fevers (with violent cerebral congestions, delirium and constipation).
7. Spiritus vita? aureus. Ruland's Golden Spirit of Life, and
Kyper's Spiritus panchymagogus were prepared from Alhandal — the
first with malmsey, and the second with anise {Mart. Rul. in suis
secret, spagyr. a Hagedornio edit. c. 31). They were both esteemed
as panaceas.
8. Emerich, the Capuchin's polychrest extract, contained, besides
colocynth, nearly thirty different substances, including, of course, the
usual drastics ; whereupon Triller exclaims — facinorosa societas,
apage !
Colocynth enters also into the composition of the Hiera Rufi, the
Pil. lucis of Mesue, the Pil. de Hermodactilis majores, the Pil.fos-
tidai majores et minores, the Pil. cachecticce Charas, the Pil. aperien-
tes Stahlii (with aloes, cinnamon and iron), the Pil. hydragogce of
Schlesier (with gamboge and croton oil), Janin's diuretic pills (a chaos
of drugs which in grossness of conception falls little short of Emerich's
polychrest, containing fourteen other purgatives), Morrison's pills (with
aloes, jalap, gamboge, and rhubarb aa.), Halle's elixir vita?, the Elixir
purgans Herlini, the acoustic essence, Barbett's Spiritus aurium, the
Unguentum de Arthanita (Rad. Azar. Europ.), the Oleum contra
vermes, Habakuk's oil,f and in many other pharmaceutical compounds,
which are now, thank Heaven, mostly forgotten.
CHAPTEE IV.
Knoioledge of the positive effects of Colocynth on the healthy
Organism before Mahnemann.
The knowledge on the subject of the effects of Colocynth on the
human body previous to Hahnemann was principally derived from a few
cases of poisoning which chance had presented to the observation of
Stalpaart Van der Wiel, Tulpius, Hoyer, Plater, Hoffmann
and others. We shall be pardoned the slight anachronism, if to these
older cases we add, for convenience sake, a few of later occurrence.
* "Ipsa (confectio) diffusa mole et formula non congruens saculi moribus,
quod doses exiguas amaf. et sectalur." Thus a century before Hahnemann
Schulze wrote his dissertation in 1734 — the world of patients were already de-
manding homoeopathic doses ! This electuary, with the application of dialtheea
to the soles, cured a constipation that had withstood every other remedy (Fried.
Hoffmann, opera o?nnia, torn. 1, pars II, c. 5, and Schulze op. cit.) — Watzke.
t This Habakuk was Loew, the Prague professor. (See Triller) — Watzke.
Knowledge of Colocynth before Hahnemann. 297
1. Stalpaart Van der Wiel (Observ. cent. I, obs. 41) relates the
case of a young, vigorous tavern-keeper at the Hague, who being in
want of a good laxative, bought a colocynth apple, crushed and ate it.
Soon after, he was attacked with unutterable colic pains and had bloody
stools, followed by such violent cramps that he was rolled up like a
hedgehog. _ It was with difficulty that his life was saved by the perse-
vering application of the appropriate remedies.
2. A lad of 17 took a decoction of colocynth. Immediately after-
ward appeared bloody stools, horrible anxiety and fainting, great pros-
tration and death. (Hover, Ephem. Nat. curios, dec. Ill arv. 7, obs.
178.)*
3. A poor man, suffering from habitual constipation, drank a de-
coction prepared from three apples, and was affected in consequence
with such extreme colic and so dreadful a hemorrhage from the anus
that he nearly died. He was saved by copious draughts of oil and
oily enemata (Nic. Tulpius, obs. lib. IV. c. 25).
4. Plater relates two cases. The first (Ejusd. obs. lib. Ill, p. 839)
was that of a young prince to whom his physician prescribed purging
pills, but finding them ineffectual changed them for powdered colo-
cynth pulp. The patient had innumerable bloody evacuations and
severe colic, whereupon the frightened doctor took to his heels. The
second case ended fatally (I. c. p. 640). A man accustomed to purges
was in the habit of drinking wine in which a colocynth apple had been
soaked over night. He had often done it without injury, but it finally
brought on a mortal dysentery, f
5. Riedlinus, who manifests great dread of colocynth and declares
(Linear med. 1696 mens. Jul. obs. 2) that he had only employed it
once in his whole practice, saw violent vomiting ensue upon the ad-
ministration of two grains to a robust, stout-built servant-girl. Bocler
says that those who handle colocynth for a long time become affected
with vomiting (Hartmanni Mat. Med. 1745, p. I, p. 335). Saciise saw
vomiting induced by laying it upon the stomach (Hufel. Jour. 1811,
April).
6. Michaelis (Kleiner? s Rep. Jahr. 7, 10, 95) states that the
extract of colocynth laid upon the bare skin of the epigastrium, pro-
duced diarrhoea.
7. Chretien noticed frequently increased evacuation of faeces and
urine from the external application of colocynth upon the abdomen
(Univ. Lex. der Pr.Med. u. Chir. Leipz. 1839. Art. Jatroleptica).
8. C. G. Neumann states that violent colic and frothy diarrhoea
* Hoyer refers in the same place to the case of a man who had been so
powerfully purged by colocynth, that no other purgatives would subsequently affect
him. — Watzkc.
t The quotation from Celsus, given by Schulze in elucidation of this fact, is
wor.hy of the attention of provers. '' Possunt qvadam subesse corpori vel ex
infirmitate ejus, vel ex aliquo affectu, qua vel, in alio non sunt, vel in hoc alias
non fuerunt eaque per se non tanta, ut concitent morbum, tamen obnoxium
magis aliis injuriis corpus cjjiciunt." — Watzke.
298 Colocynthis.
with blood were produced by frictions witb tincture of colocynth (\)
and castor oil (£) (Bemerk, ub. die gebrduch. Arzneim. S. lo).
9. Fordyce relates (Fragm. Chir. et Med. p. 66) that a woman
who had taken an infusion of colocynth in beer, had suffered thirty
years (?) from colic! Friederich Hoffmann [Op. omn. Gen. 1740,
pars III, p. 332), observed the frequent sudden occurrence of a fatal
inflammation of the intestines after the use of colocynth in ascites.
10. Joh. Moritz Hoffmann was fortunate enough to witness one of
the best cases of this sort. We insert his fine description in his own
words : " Ex generosa familia nata matrona tenera, post acidularum
Egranarum finitum potum ex recepto more a sordibus residuis repur-
gatura, pomurn colocynthidis vini cyatho per noctem infundit et inse-
quente matutino tempore ebibit. Ast pessimis suis rebus. Accedebat
siquidem mox insignis cardialgia, superveniebant vomitus creberrimi
et cum ventris torminibus atrocissimis dejectiones alvince, primo
mucoso-serosce, mox biliosos, tandem cruentce; sitis aderat clangosa atque
supcriorum et inferiorum artuum musculares fibres in subsultus et
motus agiiabantur spasticos ; febrili ceslu totum corpus exardescebat ;
demum cam animi deliquiis extremorum frigus notabatur ut adeo
terrore et metu perculsi, adstantes me advocare curarhit " (Eph. Nat.
cur. Cent. X. obs. 30).
11. Scheel observed a similar case of poisoning (Beitrdge Meck-
len. Aerzte zur Med. u. chir. von Hennemann, 1830 B. 1, H. 2). A
woman upwards of forty had for a long time been affected with rheu-
matic pains in the left shoulder and thigh. A tailor advised her to
boil half a pound of colocynth (gichtbeeren) in a measure and a half
of red wine, and to drink the strained liquor before going to bed. For-
tunately she divided the liquid into two parts ; for she had hardly
swallowed the first half before she was seized with frightful pains in
the gastric region, great anxiety, vertigo, fainting fits, and convulsions.
Frequent vomiting set in, followed by no relief; then evacuations, first
fluid and feculent, then almost pure blood with dreadful tenesmus ;
the quantity evacuated amounted to five measures, and was accompa-
nied by pieces of the intestinal lining membrane from 2 to 3 " square.
The pain then became concentrated in the stomach and lower part of
the rectum ; the abdomen fell in ; finally the tenesmus ceased and she
fell gradually asleep. The most effectual remedies were oleosa, mu-
cilaginosa and opium. The patient was obliged to keep her bed a
long while from weakness and dyspepsia, but was at length wholly
restored.
12. The Mowing case related by Carron dAnnecy was not so
fortunate (Orfild's Toxicol. 2d Edit. p. 34). A man, jet. 28, who
suffered from bleeding piles and dyspeptic troubles, drank two glasses
of a decoction of colocynth, and experienced colic, frequent stools, and
some hours later, great heat in the bowels, dryness of the pharynx and
unquenchable thirst. Dr. Carron found the patient with a small,
accelerated pulse, tongue red, abdomen tense and very sensitive to the
touch, especially in the umbilical region, bowels constipated. Vene-
Knowledge of Colocynth before Hahnemann. 299
section, emollient fomentations, enemata and poultices were of no ser-
vice, and on the succeeding day the abdomen was still more painful
and tympanitic. Another bleeding and warm bath, and in six hours
afterwards the pains had increased, there were retention of urine, re-
traction of the testicles and priapism. A dozen letches to the anus,
cupping on the abdomen and saltpetre injections. On the third day
the retention of urine diminished, but the other symptoms continued ;
the pulse was small and contracted, and hiccough, coldness of the
extremities and clammy sweat on the head and chest came on. In the
evening the pains ceased, the bowels sank and there was manifest fluc-
tuation ; the patient died in the night. Post-mortem examination.
Intestines red with black spots, for the most part glued together with
fibrine (false membrane) ; a whitish fluid had been effused into the
abdomen filled with a quantity of white flocks ; ulceration here and
there in the villous coat of the stomach ; traces of inflammation in the
liver, kidneys and bladder.
13. Dr. Carron was also called to see a young washerwoman who
had drunk a decoction of colocynth and suffered from violent colic in
consequence. Baths, oily, mucilaginous drinks and opium soon restored
her.
14. The same author gives the case of a cachectic baker who took
a decoction of colocynth for a quartan fever. He was cured of his
fever, but remained weak, debilitated and chlorotic-looking, and died
in six months of paralysis (Orjila, Toxicol, gener. 3, edit. p. G95).
15. Orfila {Op. cit.) heard of a man who took three colocynth
apples to cure himself of a gonorrhoea of several years' standing. Im-
mediately afterwards he had violent colic pains in the epigastrium and
free vomiting ; in two hours, copious stools, giving w y ay of the lower
limbs, dimness of sight, deafness, vertigo and slight delirium. The
symptoms gradually disappeared after drinking copiously of milk,
which caused vomiting, and the application of leeches to the abdomen.
16. The most interesting and instructive case of poisoning by colo-
cvnth is related by Duvergie and Ratier {Univers. Lex. der pr.
Med. u. Chir. Art. Coloc). A man fifty-five years old, of strong con-
stitution, took for a swelling on the right knee a small quantity of a
liquid which he had received from a female quack, and which subse-
quently proved to be tincture of colocynth. He was shortly after-
wards seized with nausea and vomiting, with a feeling of heat and
burning in the epigastrium. Full of insane joy at this result, he took
a second and third dose to increase the effect. Copious, exceedingly
frequent stools now came on, and such intolerable pains in the whole
abdomen and so violent a colic that he sprang out of bed and rolled
himself on the floor. And so infatuated was he that in the midst of
his greatest suffering he blessed the hand that had administered the
poison and pressingly besought the bystanders to give him a fresh dose
of it. Convulsions of the most violent character soon set in, and the
patient died in the evening. Post-mortem examination. The menin-
ges were found white and somewhat thicker than natural ; the cerebral
300 Coloajnihis.
mass tolerably firm, but neither presenting red points nor injected ;
a small quantity of rose-colored serum in the lateral ventricles and
cranial cavity ; the vessels at the base of the brain somewhat engorged
with blood. Lungs perfectly normal ; stomach and duodenum exter-
nally purple, small intestines rose-colored ; the mucous membrane of
the first was vividly reddened, full of erosions, loosened and very easily
removed. Similar abnormal appearances were found in the lower half
of the small intestines, but less decided, and the large intestine was but
little colored either externally or internally. The whole intestinal
tract was empty.
It cannot be denied that the occurrence of such tragic cases of colo-
cynth-poisoning is not calculated to induce practitioners to prescribe
the drug at the bedside. Doubtless the original diseases of the stomach
and bowels for which these individuals took the colocynth, played
no small part in contributing to the violence of the symptoms ; but
inasmuch as in this very violence, the peculiar characteristics of colo-
cynth are strongly marked, that circumstance detracts but little from
the value of these involuntary physiological experiments. We have
only to desire that some of the relaters had been more accurate and
circumstantial in their details, and above all that we had an account
of the post-mortem appearances in all the fatal cases.
CHAPTER V.
Hahnemann's Proving of Colocynth.
Hahnemann proved the Colocynth on himself and on six of his
pupils. If we may draw a probable conclusion from the known effects
to the unknown cause, we might infer that Hahnemann, Stapf, Ruckert,
Langhammer and Gutmann experimented w 7 ith rather small doses,
and Hahnemann's son Frederic and Hornburg with larger. The pic-
ture* of drug disease are obscure and lustreless ; the characteristics of
colocynth (which we have indicated in italics) are for the most part
only hinted at, seldom sharply displayed.
1. Hahnemann's Proving.
Hahnemann, in other cases the very model of a bold drug prover,
seems rather to have slighted colocynth ; his own proving presents but
few symptoms.''" Bilious regurgitations, grumbling in the abdomen,
water in the mouth, desire to drink without thirst, insipid taste in the
mouth after drinking, pressure in the scrobiculu.3 ; constant pressure
K * We have omitted the symptoms which Hahnemann himself designated as
doubtful in the first edition. Why he removed the sceptical brackets in the
third, he does not inform us. — Watzke.
Hahnemann's Proving (1). 301
and bruised pain through the whole bowels ; tearing and tension in
the left side of the face ; sticking, tensive paiu between the shoulder
blades, obliging to walk bent over; bruised pain in the small of the
back ; drawing tension in the right thigh ; paralytic pain in the knee ;
weakness of the legs ; shorter breath (for some days); coldness of the
body; vivid distressing dreams ; impotence.*
It is very doubtful whether Hahnemann himself, not to sperk of
others, would have recognized the action of colocynth in such grey,
misty shadows of subjective symptoms, had he not known the drug
beforehand.
2. — Stapfs Proving.
Stapf 's Proving is but little more characteristic. " Metallic taste on
the point of the tongue ; scraping in the palate ; fine sticking on the
velum palati as if from a beard of grain ; scraping and tickling in the
larynx, causing a dry cough (after an hour) ; colicky pain and dis-
charge of flatulence, with some inflation of the abdomen ; empty feeling
in the abdomen as if after a diarrhoea ; vertigo when rapidly turning
the head; pressive headache along the sagittal suture aggravated by
moving the head and stooping ; itching sticking in the ear ; compressive
pain in both the large cervical muscles (sterno-cleido mastoids?) disap-
pearing on motion."
3. — Ruckerfs Proving.
In Riickert's case, too, it is hard to discover an occasional glimpse of
* In the third edition, Hahnemann adds, among the " symptoms observed
upon himself," some thirty new ones. '' The highest ill-humor, and peevishness ;
the roots of the hair are painful ; excoriated pain in the eyelids ; stinging burning
under the upper eyelid ; painful looseness of an inferior incisor ; tasteless saliva
in the mouth (Is not the saliva normally tasteless ? Ed. CEst. Zeit.) ; bitter taste
in the mouth after drinking beer ; pressing pain in the stomach ; occasional vio-
lent inflation of the abdomen ; bruised pain in the hypogastrium, worse when
walking and when sitting bent over ; flatulent colic towards midnight, pain in the
groin as though a hernia were protruding and as if it were replaced on pressing on
the spot (for 'half an hour); squeezing from the side of the hypogastrium towards
the groin ; cuttings and stitches in the bowels from accumulated flatulence ; itch-
ing stitch in the rectum ; blind piles with pain in the anus ; tearing through the
urethra and glans ; itching in the right testicle ; violent sexual impulse with erec-
tions—nocturnal attack of asthma, with slow heavy breathing inducing cough ;
pressing drawing in the arm-bones ; cramp in the calves ; tearing in the heels ;
unusual disposition of the muscles to cramp; stinging itching here and there in
the evening in bed, preventing sleep; irresistible propensity to sleep and inclina-
tion to lie down ; sleeplessness."
Hahnemann does not tell us whether he had made any new provings of colo-
cynth, and as it is well known that many of the symptoms of his antipsoric reme-
dies were derived from the sick, and as we see also that he puts the symptoms of
those affections which were cured bv colocynth side by side with those obtained
from provings on the healthy, and finally, as these symptoms, if obtained from
actual provings, are partly sufficiently established by other more reliable testimony
and partly seem to present a picture foreign to the effects of colocynth as exhibited
in our researches -for these reasons we have thought fit to surround them in our
pure Materia Medica with the most conspicuous of sceptical brackets.— Watzke.
302 Colocynthis.
the characteristic symptoms of Colocynth: — "Slight pressure in the
head ; feeling of thirst in the pharynx ; sensation of pressure in the
gastric region and feeling of hunger especially after eating; cutting
pressing and transitory cutting in the epigastrium ; pressure on the
chest and in the bowels especially when sitting bent over and in the
evening, for six days ; excoriating cutting in the hypogastrium, com-
mencing ivhen walking and increased by every step (after 5 d.) ; hard
stool (after 5-6 d.) ; pressure with a dull stitch in the scrobiculus ; dull
stitches in the right chest during inspiration, after an hour, during
expiration after six days ; stitches under the false ribs and scapula ;
stitches (after 4 h.) and bruised pain (after 5 days) in the arms ; sticking
tearing and tearing sticking in the thigh ;* tensive pressure on the tibia;
tearing in the calves; pressive tearing in the ancle; feeling of warmth
creeping over the whole body (after 2 h.) ; he feels unwell, peevish and
taciturn.
4. — F. Hahnemann's Proving.
The symptoms of F. Hahnemann appear to be the result of more
numerous and somewhat energetic provings — though few in number,
they still sketch out the Colocynth picture in bold strokes.
Soon after the dose, bitterness in the mouth and severe nausea, the
first lasting four hours, the other on one occasion two, on another eight
hours; accompanied by rough feeling on the tongue as if from sand.
In one experiment the nausea was followed by twice vomiting of food.
After the lapse of scarce an hour there came on with violent chilli-
ness, vertigo and dulness in the head, pain across the hips and
trembling of the feet (as if from fright) ; dreadful colic extending from
a little spot beneath the navel and spreading {after eating) over the
whole abdomen obliging him to bend forward and double himself up.
In another proving, the colic remained fixed in a single spot in the
umbilical region; it was ^ticking, compelled him to bend forward, was
much aggravated by straightening himself up and lasted eighteen
hours. The colic became much less in both instances after oreen/sh
yellow diarrhoiic stools, in the first experiment fifteen in eighteen hours.
It was also ameliorated by smoking tobacco.f
5. — Langhammer 's Proving.
We give these symptoms in his own chronological order. "Dull
stitch in the forehead; shuddering over the whole body with cold
hands, the face and rest of the body being warm, without thirst ; noisy
discharge of flatulence; frequent urging to urinate with scanty emission;
* The timid prover generally recognizes dimly and with difficulty his
doubtful symptoms, and hence hesitates and wavers in his choice of words to
express them. A well developed drug disease gives the prover but little
trouble in the selection of his descriptive terms. — Watzke.
f The potato was probably only accidentally connected with the violent
colic and rapid evacuation which followed the eating of it (S. 87). — Watzke.
GutmanrCs Proving (6). 303
white tongue (in the morning as if after much smoking) ; fluent coryza;
whistling inspiration ; hiccough; pimples in the face; violent headache
disappearing in the open air ; tearing in the dorsum of the foot ; violent
drawing in the right thumb; tearing sticking in the whole hody;
itching in different parts now here now there ; boring stitches in the
temple ; weakness^ with trembling of the legs and sweat over the whole
body ; pressive pain in the orifice of the urethra after urinating ; hacking
cough when smoking; sleep disturbed by voluptuous dreams ; sweat on
the legs early on waking ; disinclination to talk.
A proving which comes exceedingly near to having no significance
at all ! There is but little sign of Colocynth in the whole of it.
6. — Gut?nann''s Proving.
Gutmann's proving presents us with an excellent but at the same
time a very anxious prover. What a pity he only experimented with
small doses ! Our numerous experiments lead us to the opinion that
many of the following symptomatic minutiae are simply due to the
strained attention of the prover.
" Dulness of the head especially in the sinciput; tearing pain in the
whole brain, aggravated by moving the upper eyelids; pressing head-
ache in the sinciput aggravated by bending forward and by lying on
the back (lasting six hours) ; burning pain in the cheeks, skin of the
forehead, scalp and eyelids ; itching, burning and cutting in the ball of
the eye; compression, crawling and cutting sticking in the ear ; thump-
ing and digging pain from the middle to the root of the nose; twitching
in the muscles of the chin ; tearing in the inner side of the cheek and
on the point of the tongue ; stitches in the fauces ; foul taste ; bitter
taste after drinking beer ; tensive, griping colic, disappearing on pres-
sure; tension and boring in the groin ; digging and tearing in the
umbilical region, aggravated by expiration and laughing; hard stool ;
sticking in the right loin only perceptible during inspiration, tvorst
when lying, on the back; itching stitch in the anus ; creeping and
crawling on the chest and abdomen ; griping and muscular twitchings
in the right ribs ; excoriated pain in the left scapula; prickling burning
in the right upper arm ; itching sticking in the bend of the elbow ;
tension in the forearm ; cramp in the palm so that he can scarcely open
his fingers; pain in the right thigh, as if the psoas muscle were too
short, only when walking; needle-like stitches in the ham, on motion ;
pain in the varices of the leg; vibrations, sharp cutting, itching sticking
in the calves; itching, boring stitch in the dorsum of the foot; tearing
in the right sole, worst when at rest; somnolence ; lascivious dreams ;
depression ; disinclination to intellectual labor ; disinclination to talk.
1. — Hornburg's Proving.
This is by far the best of the Hahnemannian provings. Like F.
Hahnemann, he probably made repeated experiments and in none of
W
304 Colocynthis.
his colleagues do we find the characteristic symptoms of Colocynth
stand out so strongly pronounced.
"Head dismal and dreary as if after a, night of debauchery ; draw-
ing, one-sided headache (after -£• h.) ; pressing and drawing behind the
left ear; pain in the left lower row of teeth, as if the nerve were
drayged; empty eructations; pressure in the stomach as if from a stone;
empty, at another time full, feeling in the abdomen; sensation in the
bowels as if from having caught cold or improper mixture of food;
yrowliny, griping, cutting, crampiny and pinching in the abdomen;
increased constriction in the hypoyastrium every te"n or twelve minutes,
accompanied by an internal shuddering through the cheeks ascending
from the abdomen ; pain in the whole abdomen and especially below
the navel, as though the bowels were squeezed between stones occasion-
ally so severe that the blood rose into his face and head and sweat
broke out on these parts, with muscular distortion of the face and
closiny of the eyes. He could neither lie quietly nor hit and could
only walk entirely bent over. The pains vjerc ameliorated by pressure
with the hand and by bendiny forward; they also became less after
violent exercise and turning around ; they disappeared entirely after a
cup of coffee. Violent, frequently rccurriny inclination to stool which
could only be resisted by the stronyest efforts. Stool, scanty, tough and
mucous or copious, yellowish-brown, thin, frothy with a sourish putrid
taste ; accompanied by a feeling at the termination of the rectum as
though the parts had been weakened by a chronic diarrhoea. The
colic was relieved by the evacuation but soon returned. Rumbling of
flatulence ; inclination to stool immediately after eating; continuous
pressure over the pubes with frequent uryency to urinate and scanty
emission. JDraiviny pain from the riyht side of the neck to a point
over the scapula as thouyh the nerves and vessels were rendered tense;
stiffness and violent drawiny pain of the left side of the neck and nape,
ayyravated by motion; feeling of weight in the nape ; sprained feeling
behind the right scapula ; burning pain in the right middle finger ;
tickling pressure in the left, buttock ; the left foot goes to sleep ; decrease
of the quickness of the pulse from the commencement to" the tenth
hour ; then internal and external heat of the body : a great variety of
dreams, voluptuous, with pollutions.
Postcrint concerning some errors in the Hahnemannian
prOVillgS. It was with the greatest astonishment that we perceived
in the third edition of Colocynth {Antips. Rem. part o, Dusseld. 1837)
the name of ^Egidi among those of the provers of Colocynth and the
symptoms 22, 29, *75 and 114* referred to him and introduced among
* 22. Tearing digging through the brain, aggravated to an unbearable
extent by moving the eyelids ( Compare GiUmann's proving). 29. Stitches as
if from knives in the right eyeball extending to the root- of the nose. 7 5.
Empty eructation causing palpitation and cramp in the pharynx and keeps
up a constant inclination to choke and vomit. 114. Periodical attacks of
frightful cutting in the abdomen extending from the renal region and drawing
the thigh convulsively up to the abdomen, so that the patient had to assume
the most bent position possible. — Watzkc.
Errors in the Hahnemannian Schema. 305
those resulting from provings upon the healthy organism. These are
the preliminary symptoms of a disease which ^Egidi cured with Colo-
cynth ! We shall subsequently allude to the case further.
Hahnemann also cites in addition to Stalpaart, Hoyer, Tulpius,
Plater and Hoffmann, whose observations we have introduced in the
original in the foregoing chapter, Zacutus Lusitanus, Schenk,
Kolpin and Salmuth, as authorities upon the physiological effects of
Colocynth.
The flux of Zacutus Lusitanus (Sympt. 101, first edit, to which
we always refer because we consider it the best) is not the result of an
experiment but a mere conjecture* The verification of symptom 103
u Haemorrhage from the anus some hours after death " cost us consi-
derable trouble. Hahnemann cites Schenk for it ( Obs. med. rar., lib.
VII, obs. IV.) ; Schenk cites Cameuarius (In horlo med. et phil.) and
he refers us to Dodonjeus (Med. obs. exempl. rar. Luyd. Bat. 1685,
p. 22) where we are first informed that the symptom was most probably
derived from an apoplectic subject. " Monendum nonnullos colocyn-
tkidis manipulum — drachmam — dccoctis ad enemata Apoplecticorum
addere. Tale autem decoctum frequenter ad duo aut tria enemata
sufficit. Excessus enim colocynthidis (in enemate) piericulo non caret.
Abradit enim ho3c intestina et oscula aperit venarum. Memini ah
enemate cui incocta fuerat colocynthidis drachma, hominem robustum
non diu superfuisse et mox post mortem, aliquot deinde horis sanguinem
copiosum per sedem effluxisse.' 1 '' Symptom 103 then should read thus,
" Copious haemorrhage from the anus appearing soon after death and
continuing some hours." So far as we ourselves are concerned we
should say that neither the death nor the flux of blood had any thing
to do with the clyster. Dioscorides also has observed anal haemor-
rhages succeeding Colocynth injections (Op. cit.), but never in the
healthy nor indeed in the dead.
Symptom 176 cited from Kolpin, "Itching of the shin with sweat
immediately following;" 177, from the same, "Scabious eruption"
(erroneously referred to Hoffmann in the third edition) ; and 144,
" Abscesses under the shoulder and in other parts of the body" are of
no value whatever on two grounds. First, because they were not
observed in the well but on the sick, and second, because they would
in all probability have equally manifested themselves as what are called
critical phenomena, after the administration of any other drug proving
to be the specific in the given case.f The same remark applies equally
* Colocyntlris per se sola offerri non debet, nam fauces et guttur veliementi
incendio vexat, corpus injlammat , viscera dolore conturbat, abradit intestina,
ora venarum aperit et dysentcriam molitur. (Zac. Lus. Op. Lugd. 1667, torn.
II, p. 93).— Watzlce.
\ That the reader may judge, we give KoLriN's ease in full. A man, ret. 40,
contracted a rheumatism in the nape in consequence of catching cold. Six
mouths afterwards he presented the following ease. "Upper and lower
extremities unsusceptible of motion; obstinate constipation; dischaz-ge of
urine at times involuntary, at times suppressed; the hypogastrium from the
306 Colocynthis.
to symptom 179 cited from Salmdth, " Scaling off of the skin of the
whole body."* The whole of these symptoms are to be purged from
our Materia Medica Pura!
CHAPTER VI.
Martin 's Proving of Colocynth and Ms Society for Provings
in Jena.
Martin and his society, at least as far as their results are exhibited
in Noack and Trinks 1 Arzncimittellehre, have not remarkably enlarged
our knowledge of the action of Colocynth. The experimenters appear to
have been somewhat too apprehensive and anxious ; the symptoms
obtained do not bear the impress of a drug-sickness but look rather like
fragmentary and purely subjective phenomena. We designate by the
types, whatever we seem to recognize in them as characteristic of
Colocynth.
" Heaviness of the head ; susceptibility to intoxication (from beer) ;
dulness of the head; vertigo; transitory deafness with roaiing in the
ears (after eating) ; aching in the forehead (with colic and urging to
stool); pressure over a spot in the linea semicircularis; burning in the
head and face; painful drawing in the face, alternating with itching and
navel to the pubie region distended by a sometimes spherical, sometimes
longish swelling. Alter purges, the swelling disappeared and the urine was
discharged voluntarily, but on the other hand clonic convulsions of the lower
limbs set in whenever the patient was raised or touched. After a fruitless ,
employment of various remedies, twelve drops of tincture of Colocynth were
given him every two hours. In a fortnight there was a manifestation of
motor power in the lower limbs. At the end of five weeks there came on
every afternoon troublesome itching with subsequent sweat, whereupon the
power of the extremities increased (but still more in the evening than during
the day). In the fourth month of the treatment the patient has an itchliko
eruption, and as this disappeared, abscesses formed under the shoulders and in
other parts of the body. During this time there was free motion of the limbs
and the patient was perfectly well. The numbness and want of motive power
lasted longest in the ends of the fingers. — (Hufel. Jour., 3, 575). — Watr.ke.
* Salmutu's ease is as follows; (Obs. med. Brunsv. Cent. III). Robert Ven-
thuseu, a valet-de-chambre in Anhalt, became sick while a soldier at Rot-
terdam. A comrade had pi-escribed as a laxative an Elixir prepared from the
pulp of a whole Colocynth apple. Besides the usual symptoms accompanying
the accidental ingestion of the drug, there came on, not only bloody discharges
from the anus but also from the mouth. These latter were violent, continuous,
lasting several days and reducing the patient to such a state of debility that
he had not strength to open his mouth and spit out the blood, but it was
removed by the fingers of the bystanders. The physicians gave him up as
lost and departed, but an old woman gave him common oil with beer to drink
morning and evening and saved him in spite of the doctors. During his con-
valescence the whole epidermis scaled off in pieces the size of a dollar; it took him
seven weeks to recover his strenath and his skin. — Watzke.
Martinis Experiments. 307
accompanied by pain in a molar tooth ; teeth on edge ; canine hunger
and heartburn afterwards in the throat; sour eructation; pressure in
the stomach (after eating) with headache, indolence, gloomy ill-humor,
flatulence and diarrhoea ; rumbling in the stomach ; great heat in the
stomach; aching and pressing, constrictive dull-sticking pain in the
scrobiculus ; colic with a feeling as if diarrhoea were coming on; violent
colics with restlessness and benommenheit {? /) of the body (the pains
diminished after a thin evacuation; fluid evacuation followed by weak-
ness, paleness and exhaustion ; violent itching at the anus ; diminished
secretion of urine; pollutions at night; oppression (about the heart) ;
■constrictive pain in the fore-arm ; painful, constrictive pains in the hand
and from there towards the fore-arm, alternating with similar pains in
the cheeks and abdomen ; painful drawing in the fore-arm and thigh
alternating with itching ; little ulcers upon the skin, itching and
burning ; unusual burning of some slight cracks ; great liveliness and
11 i . ^ ® ' O
sleeplessness ; alternation of heat and coldness ; frequent, momentary
but ever recurring sweat and fainting vertigo, ameliorated by covering
the eyes with the hand ; clammy moisture on the head and chest ;
copious sweat smelling like urine on the head, hands, legs and feet;
peculiar frame of mind which will allow no thought to be attentively
considered."
CHAPTER VII.
Hechenherger's Kolocynthognostik.
Colocynth has in Dr. Hechenberger an ardent advocate and a stout
defender, but a timid prover and a weak observer. His monograph* is
one, the like of which, in spite of its deficiencies, we could desire to see
multiplied among our opponents. Noaclc and Trinks rank him among
the old school, but it seems to us not altogether justly — for he is a
Homoeopath, at least in respect to Colocynth, though a secret one and
a particolored.
The symptoms observed and recorded by him are mostly confined
to the intestinal functions. He seems to have exhausted the whole of
his observing power in the how and the when of the alvine evacuations.
A single drop of the tincture administered morning and night, in a
tablespoonful of water, seemed to have no effect upon persons not
endued with special irritability, during the first five or six days. On
persevering in the use, a copious strikingly brown, frequently black
stool came on preceded by painless borborygmi. If the dose were still
continued, the stools kept growing thinner, but always brown, with
lively rumbling in the bowels. After three months' continuance of this
* Kolocynthologie odcr Beobaehtungen itber die vortreffiichen, vicl zu wenig
beachtetcn, Heilkrafte der Kolocynthis. — Insb. 1840.
308 Colocynthis.
dose, Hechenberger bad regularly a single soft stool in tbe evening of
tbe same day.
A drop given early in tbe morning and repeated every two bours
brought on diarrhoea in persons not torpid, by the afternoon and even-
ing, but without colic or the usual inconveniences. From four to eight
drops in a single dose in the morning occasioned slight diarrhoea the
same afternoon, or at farthest the next morning, preceded by griping in
the umbilical region.*
The further almost constant symptoms from the continued use of
Colocynth were: Striking increase of appetite and thirst; more copious
secretion of urine, the urine being often light-brown like beer, and
becoming cloudy on cooling, a copious, sometimes sandy, sediment being
deposited ; noisy discharge of a great deal of wind; gentle, painless
renewal of the hemorrhoidal flow, but leaving behind a peculiar burn-
ing around the anus and along the sacral region; menses more profuse
and too early.
A pregnant woman who had taken a tablespoonful of the tincture of
Colocynth was attacked in five hours with dysenteric diarrhoea, bloody
discharge and a severe burning pain along the sacral region. This was
accompanied by violent swelling of the labia with feeling of bearing
down and beat in the vagina. A little tincture of Opium in warm
milk soon removed all the symptoms except the swelling of the vulva,
which was unusually troublesome during the whole period of pregnancy.
Secondary torpidity of the prima: vim, as a consequence of long
continued use of Colocynth, was not observed by Hechenberger either
in his own case or in that of others.
CHAPTER VIII.
The Vienna JProvings.
We choose Jorg as our pattern in describing the results of the
proving. Our reasons for so doing are apparent from our Introduction.
We repeat, that we do not see that it is possible to understand aright
the positive effects of a medicine when no insight is given into the
development, succession, intensity, and duration of each case of medi-
cinal disease, or into the character of the different symptoms, and that,
* In order to avoid anything out of the way in his practice that is to say,
to avoid the reputation of being a Homoeopath, Hechenberger ordinarily
concealed the admirable effects of his Colocynth in a vegetable decoction
(Graswurzelabkochung) from one to three drams of the tincture to the pound
and administered a half or whole tablespoonful every two hours — a respectable
dose, inasmuch as every tablespoonful contained from two to eight grains of
the tincture. The mixture had to be preserved in water : it was omitted as
soon as the least trace of grijnng was perceived. There was no perceptible
effect for the first day, but on the continued use followed in the afternoon and
finally in the forenoon also, griping boring and digging, especially in the
flanks, and a soft diarrhoea in the evening or at night. — Waizke.
TJie Vienna Provings. 309
in fact, it is this deficiency in Hahnemann's Materia Medica that makes
a revisal of it necessary. If it is said that the reading of individual
cases of medicinal disease is equally a tax ?nd a task, and that our
Materia Medica will by this means grow to a huge mass of thick folios,
and that, after all, an arrangement of the symptoms according to an
artificial fixed plan will become necessary ; we reply that we see this
perfectly well, but know of no remedy. Let our colleagues who use
this language console themselves with the reflection that it is at all
events more easy and amusing to read such records of experiments than
to make them on one's own body. The hyper-scrupulous particularity
of Koch, who proved Calcarca, with his cloudy mornings, sunny days,
and cool evenings, and the anxious observations of others on the changes
of the moon and variations of the barometrical, thermometrical, and
hygrometrical states of the atmosphere, will not be found in the records
of our experiments. We have to come to the conclusion, frjm our trials
with Colocynth and other medicines, that they are, if not of absolute,
yet of so considerable an influence over the human frame as to be
scarcely if at all affected by such causes.
Have we set to work in the proper manner ? Was our mode and
manner of experimenting the true Hahnemannic? Those will doubt
it who think they hive in the decillionth doses Hahnemann's secret of
winning symptoms. We confess that the favourite maxim of so many
provers of medicines — to make themselves as little sick as possible, or
if possible, not sick at all — does not please us. (We regret to see it
adopted by some of our colleagues, and these are those who send us
subjective symptoms.) Our opinion is, that if our Materia Medica is to
become what it must one day be, a science, a systematic knowledge of
the families, orders, and species of medicinal diseases, it is not enough
simply to experiment with doses barely sufficient to excite re-action ;
we ought rather to take doses so large and so long continued as to
penetrate the system to a certain degree, and to exert a lasting effect
on the various organs and their functions ; nay, further, we must, at
least in the case of the lower animals (fatal cases occurring to human
beings affording a most important supplement), experiment in such a
manner as gradually to accumulate the needful materials for an anatomy
of medicinal diseases, until supplied with which the science of pharma-
codynamics must remain imperfect.
Our association for the proving of Colocynth consisted of fifteen
members, the results of whose experiments we give below in alpha-
betical order. We have only further to remark, that we used the
tincture prepared as Hahnemann directs, and that almost all of the
provers were ignorant as to what medicine they 'were proving.
8. — ArnetKs Proving with the Tincture.
The proving of our colleague, Dr. Franz Hector Arneth, though
one of the poorest in symptoms, is, in reference to the theory and
practice of Homoeopathy, one of the most interesting.
310 Colocynthis.
Arnetk is 25 years of age, of choleric temperament, and strong con-
stitution. In spite of vaccination when a child, he took the small-pox
when 21 years of age, and got favorably through it. Since that time
lie has enjoyed uninterrupted good health.
Will he attribute it to our desire to meet the scepticism of our
macroposological opponents in reference to the rarity and paradoxical
character of his results, if we add to this physiological portrait drawn
by himself, its psychological complement ? We may say, then, that
our colleague possesses as sound an understanding, as unprejudiced a
spirit of observation, as much acumen, honorable feeling and devotion
to the truth as the very best of our opponents.
1842, Nov. 1st. 1.30 a.m., one drop; 11 am., five drops; 9 p.m., ten
drops tincture of Colocynth. He did not perceive the slightest result.
Nov. 2d. 6 a.m., ten drops; 11 a.m., twelve drops; 4.30 p.m., twenty
drops, and two hours afterward twenty-five drops. No result.
Nov. 7th to 13th. Ten drops three times a day on the first, increas-
ing the dose one drop every subsequent day. The result was equally
fruitless, not the slightest trace of the effects of Colocynth appearing.
Nov. 14th and 15th. Forty-five drops twice a day on each day.
From the 16th to the 23d he omitted the medicine and during this
time he had, contrary to his usual habit, two pappy stools a day, with
slight griping in the epigastric region.
Nov. 24th to 26th. The evacuations having become regular again on
the 24th and 25th, he took at 1 p.m. of the 26th fifty drops of the
tincture. Two pappy stools, one that evening, the other next morning,
and abundant urination, were the only symptoms which he observed.
Nov. 27th. Seventy drops, taken at 11 a.m., increased the secretion
of urine that day, and gave rise on the following day to griping in the
epigastric region after each meal, worse towards evening, and pretty
severe drawing pain in the left testicle, lasting about a quarter of an hour.
Nov. 29th. Eighty drops of the tincture at 2 p.m. Next morning
a furuncular eruption made its appearance on the face, and on the 2d
December another on the back. Both disappeared in a few days.
This concludes Dr. Arneth's experiments with the tincture, which he
took pure and without a vehicle.
9. — Arneth's Proving with the Dilutions.
Dec. 7th. All traces of the former action of the medicine having
disappeared for a long time, he took, morning and evening, two table-
spoonfuls of the third dilution of the tincture of Colocynth, prepared
in the proportion of 1 Colocynth to 100 distilled water, and had after
it two pappy evacuations.
Dec. 8th. Next day two tablespoonfuls of the third dilution, shortly
before going to bed ; he had scarcely got into bed before he experienced
in the epigastric region more violent griping than he had formerly felt
from the mother tincture, but which did wot bring on an evacuation.
Dec. 9th. He took, morning and evening, two tablespoonfuls of the
Arneth'' s Proving (9). 311
third dilution, and had each time two pappy stools ; he then passed to
the second dilution of the tincture.
Dec. 10th to 14th. He daily took two tablcspoonfuls about noon.
Dec. 11th. Towards evening, irritability of the larynx began, and
the voice became rough and hoarse. Dec. 12th. Besides these symp-
toms, there was distressing dryness of the air-passages, and on the two
next days a perceptible and disagreeable feeling of fatigue in the affected
parts. Each time after taking the medicine, he perceived a remarkable
aggravation. From the 10th onwards he had had two pappy evacua-
tions daily.
Dec. 15th to 20th. The medicine was omitted until the foregoing
symptoms had entirely disappeared.
Dec. 21st, 22d and 23d. He took, at noon and in the evening, two
tablcspoonfuls of the second dilution each time. Nothing occurred the
first two days except the usual griping pains in the epigastric region,
which also continued on the four following days, and the two daily
pappy stools. On the night of the 23d, when lying in bed, drawing in
the right shoulder.
Dec. 23d. In the afternoon, violent drawing pain in all the teeth of
both jaws — a symptom which struck the prover the more, from his
never having suffered from toothache before.
Dec. 24th. Besides the pain (drawing and tearing) in the teeth,
which had lasted the whole day, he felt in the evening moderate tension
in the region of the anterior superior spine of the ilium of the left side.
Dec. 25th. Next day this sensation, hitherto a tensive feeling con-
fined to one point, changed into a violent drawing, extending from the
spine of the ilium to the inguinal region and the upper third of the
inner surface of the thigh; it continued pretty violent all day, and did
not disappear till the 26th, with a very singular feeling of stiffness in
the left great toe. The toothache had disappeared the preceding night.
Dec. 20th. Two tablcspoonfuls in the evening ; next day, at noon,
three, and in the evening again, two tablcspoonfuls of the first dilution
of the tincture of Oolocynth. On the 26th, before going to sleep, he
noticed a slight prickling in the conjunctiva palpebrarum, of the left
eye. Next morning it was perceptibly inflamed ;* here and there were
indications of commencing ulceration, which continued to increase till
four in the afternoon, when it was complete ; next morning cicatrization
had taken place.
" I should not," says Dr. Arneth, " have alluded to this catarrhal (?)
inflammation of the conjunctiva, such occurrences, though with no
* "We cannot sufficiently warn our friends who are proving drugs, against
the use of mere names. The symptoms should he accurately described. We
want the species facti, not the" hypotheses of the prover. Arneth calls this
series of symptoms a catarrhal injkanmation. We see in it neither catarrh nor
inflammation, hut only fusion of conjunctiva] miliary tubercles, such as we fre-
quently see upon the cornea of children. Others would see in it fragments of
a scrofulous ophthalmia with phlyctense, others something else. Such little
abseesses, however— ruptured phlyctens — commonly leave no cicatrices, at
least none visible upon the conjunctiva. — Watzke.
312 Colocyntliis.
tendency to ulceration, not being uncommon with me, did it not seem
to me likely that the unusually rapid cicatrization was due to the medi-
cine ; and I am the more inclined to this opinion from a catarrhal
ophthalmia running a precisely similar course, having been one of the
first symptoms which I noticed in the beginning of November, imme-
diately after the first doses of the mother tincture, but which I did not
put down, because its occurring once did not seem a sufficient warrant
to attributing to the medicine a malady not uncommon to me."
10. — ArnetKs Proving with Higher Dilutions.
Arneth was now desirous of ascertaining whether still higher dilutions
would affect him, and how. He first waited until he no longer perceived
the slightest trace of the former operation of the drug, and as from
Dec. 27th, when he took the last dose of the first dilution, to January 6
(1843), he experienced great inclination to diarrhoea and frequently had
three stools a day, it was only on Jan. 9th that he began the proving.
Jan. 9th. On this and. the two following days at noon two table-
spoonfuls of the fourth dilution. Soon after taking the first dose he
had violent eructations lasting about half an hour — a symptom he had
not had from the tincture nor from the lower dilutions.
Jan. 10th. Drawing and tearing in the right shoulder-joint in the
morning, lasting all day. Painful feeling of tension in the left patella in
the evening.
Jan. 11th. The pain in the patella became so considerable that
walking was painful ; patella hot and somewhat swollen on undressing
in the evening, with an indistinct pulsation in the swelling. Itching in
the anus all day. Stools natural.
Jan. 12th. The symptoms all disappeared.
Arneth could discern no effects from repeated experiment with the
fifth dilution.
Must we attribute the want of effect from large doses, while in the
same individual, small doses produce symptoms, solely to an idiosyn-
crasy of the prover ? Had the large doses which preceded in this case
excited a susceptibility for the smaller ones ? Can it be that in dilu-
tions of vegetable tinctures (perhaps exceptionally) a similar process
takes place as is known to occur in the trituration of mercury, gold,
platina and other substances, which are thus first rendered fit for
absorption into the fluids and circulation of the economy, and for the
development of their medicinal powers ? Is it not shown by Arneth's
provings that, in many cases, the cure of the patient depends solely
upon the dilutions of the drug ?
11. — B'6hm?s first Proving with the Tincture.
Dr. Jac. Karl Bohm, aat. 40, of choleric temperament, rather weak,
small, pale and lean, subject to blennorrhceas of all sorts, accustomed to
the greatest moderation, never affected with any serious illness but
atoning for every error in diet by a violent fit of colic, and apparently a
BohirCs JProvings (15). 313
highly susceptible subject for the action of Colocynth, and a very
cautious prover.
Nov. 15th and 17th. He took on each of these days, in the morning,
fasting, two drops of tincture of Colocynth, and on the 19th three drops.
There was no notable effect. A week later he took in the same manner
six drops. Immediately after dinner on the same day, violent cutting
in the hypogastrium, forcing him to stool, and a fluid evacuation.
12. — Bbhm's Second Proving.
Dec. 3d. Twelve drops in the forenoon. Slight colic in the umbi-
lical region, soon afterwards ; little appetite at noon ; violent eructation
after eating, cutting in the hypogastrium, and a fluid stool, with rectal
tenesmus. The cuttings in the abdomen and the tenesmus lasted all
the afternoon and only disappeared entirely in the evening when he
got warm in bed. He slept well and felt well on waking while in bed,
but soon after rising, he had a fresh attack of the umbilical colic and
frequent eructations. On going out he felt very weak, had little appe-
tite at noon, a fluid stool after eating, with discharge of flatulence and
painful feeling in the abdomen the whole afternoon, which was only
removed as before when he got warm in bed. These symptoms were
daily renewed from Dec. 5th to Dee. 13th, when he took Cocc. as an
antidote, and all his troubles rapidly disappeared.
13. — B ohm's Third Proving.
Dec. 24th. Bohm had the courage to repeat his experiment by
taking one drop of the tincture triturated with sugar of milk. He
repeated the dose for the next three days without the slightest result.
14. — Bohm's Fourth Proving.
1843, Jan. 3d. Bohm began a new series of experiments. How long
it was continued he does not state, nor does he give us the phenomena
in detail, but sums them up generally thus : " As often as the dose
exceeded three drops of the tincture, cutting in the umbilical region
and tenesmus came on after eating, and there remained for several days
increased sensitiveness of the whole abdomen and constipation.
Since the sensitive bowels of our colleague (at least so he thinks)
often suffered from the same symptoms without the intervention of
Colocynth, it remains doubtful whether the phenomena produced by
his few and timid experiments owed anything to the drug which he
took. The results of provings upon the diseased organism, however
carefully they may have been conducted, have, alas ! but a very pro-
blematical value.
15. — Fleischmann's Proving with the Tincture.
Dr. Wilhelm Fleischmann, set. 41, of choleric temperament, tole-
rably strong constitution, suffering for several years from various forms
of fout, began his experiments with five drops of the tincture. As this
314 Colocynthis.
produced no effect, he took on the second day ten and on the third,
fifteen drops. Violent griping in the. umbilical region lasting all day,
feeling of coldness in the abdomen, looseness of the bowels. These
symptoms lasted with more or less intensity for several days, and he
omitted the Colocynth for nearly three weeks in consequence. He
then began again with ten drops. Besides the above mentioned very
troublesome symptoms he now had during the first days discharge of
blood from the amis, which after more than a year, still continues in
greater or less quantity daily, with violent sticking and burning pain
in the small of the back and anus; he concluded he would not subject
his gouty body to any further experience with Colocynth. Before this
proving ho had never had a discharge of blood from the anus.
10. — FrohlicKs Proving of the Tincture on Himself.
Dr. Ernst Hilarius Frohlicii, set. 32, of sanguineous temperament,
light hair and blue eyes, had tinea capitis when young. Subsequently
had and still suffers somewhat from small furuncles on the face and
back, is inclined to a sub-inflammatory affection of the larynx with
hoarseness, to constipation and swelling of the hsemorrhoidal vessels;
he proved the Colocynth on himself, on two girls and on several
rabbits.
1842, Nov. 21st. Five drops of the tincture in half a glass of water
at 6 a.m. fasting. No result during the day. Ten drops in the even-
ing with the same effect.
Nov. 2 2d. Ten drops this morning fasting. No traces of action
during the forenoon, but at about half past one p.m., seven hours after
the dose, umbilical colic, with painful stitches in the bladder, and subse-
quently alternately in the rectum, disappearing on the discharge of
flatulence. This was accompanied by transient headache, feeling as if
the temples were screwed into, with heaviness of the eyelids without
sleepiness. These symptoms disappeared after a cup of black coffee
taken after dinner, except an inconsiderable griping in the left flank.
Copious discharge of clear, watery urine during the whole day, and one
soft but not copious stool.
Nov. 23d and 24th. Fri&lich woke with a slight griping around
the navel. Twenty dropi of the tincture. Half an hour afterwards
loud rumbling in the intestines, with discharge of inodorous flatulence;
griping around the navel, increased by eating fruit ; transient stitches in
the upper jaw, frequently recurring in the left flank and along the
external border of the left sole ; cramplike drawing in the right calf.
These symptoms lasted all day and did not diminish after taking black
coffee. At 1 p.m. of the same day twenty drops. The night was
quiet, but the whole of the next day, the 24th, which was foggy, he felt
uncomfortably chilly and had continual griping about the * navel. In
the evening he was very weak, the small of the back and lower limbs
were painful as if after a forced march, and a tearing sticking pain
encircled the right internal malleolus.
FrdhliciCs Provings (17). 315
Nov. 24th and 25th. Nevertheless on the evening of the same day
(24th) he took twenty drops more, and on the following morning twenty-
five drops of the tincture. An hour after the last dose an easily resisted
inclination for stool, and subsequently a half watery, half solid evacua-
tion. The ingestion of some beer (at 11 a.m.) caused violent griping in
the stomach, coming on in paroxysms and only disappearing after dinner.
No other symptoms. In the evening forty drops. This was followed
by no symptoms except a violent constrictive pain in the umbilical
region, lasting a quarter of an hour, and which waked him from sleep
the following morning at 3 a.m.
Nov. 28th and 29th. Having been several days without medicine
and without symptoms he took forty drops on each of these days in
the morning, fasting. In the forenoon, griping around the navel ;
urging to stool easily resisted ; after dinner with a little wine, the grip-
ing and urging increased, and an almost formed stool followed, accom-
panied by slight tenesmus. The colic and violent urging to stool how-
ever continued until towards 4 p.m., when a second scanty stool occurred,
accompanied by some mucus.
Nov. 30th. Frohlich concluded his experiments by taking sixty drops
of the tincture in the morning fasting, and forty drops in the evening.
The results were very trifling, notwithstanding the heroic doses. Colic
and griping about the navel, somewhat increased after dinner, and ceasing
an hour afterward. In the evening, painful lassitude in the small of
the back and lower extremities ; flying stitches in the humeri.
Dec. 1st. On the following morning, pain in the ancle coming on
when walking in the street, as if from a false step, ceasing when at
rest; feeling of stiffness in the hands, continuing longer.
Dec. 2d to 7th. Stitches in the ancle; tearing in the shoulder; a
stitch, occasionally deep, in the left flank ; feeling of weariness in the
small of the back, and a viscid, soft, scanty stool every three days.
Is this slender amount of symptoms due to the peculiar unsuscepti-
bility of our colleague to the action of Colocynth ? Or was he too
hasty in his proving, thus disturbing the normal formation of the Colo-
cynth sickness and preventing the maturing of the commencing symp-
toms ? Or, again, did he take too large or too small doses, or did he
conclude the proving too soon \ His usual manner of life was not
altered during his experiment.
17. — FrolilicKs Proving of the Third Dilution on Two Girls.
Frohlich prescribed the third dilution of Colocynth in pellets to a
weaver upwards of fifty, who suffered from pain in the small of the back,
with instructions to take five of them three times a day. The patient
was much better on the following day and told Frohlich with a smile
that his two daughters and his son had also taken the pills. The whole
three experienced symptoms similar to those of Colocynth, and Frohlich
engaged the daughters to continue the experiment and to watch their
symptoms more closely, under the superintendence of their invalid
316 Colocynthis.
brother. Both young women were intelligent, occupied in weaving,
and lived after their usual fashion, except that they drank no coffee,
wine, nor beer.
18. — First Proving with the Third Dilution.
Amalie Ph., 22 years old, a soft delicate brunette, had recovered
from chlorosis six months before, but still menstruated scantily and
looked pale.
_ 1843, April 29th. Took two pellets moistened with the third dilu-
tion of Colocynth. Soon after the dose, inodorous eructations and
unusual discharge of flatulence;* subsequently, drawing tearing pains
in the whole abdomen and in the finger-joints of the left hand.
May 1st. Three pellets. Copious, inodorous eructations; drawing
in the nape and in the dorsal muscles.
May 3d. Three pellets. Pain in the small of the back; tearing
drawing in both thighs and in the left arm down to the finger-joints.
May 5th. Four pellets. Drawing in the left hypochondrium ;
tearing in the left calf as far as the heel.
May 9th. Six pellets. Stitches penetrating deep into the abdomen;
tearing in the joints of the left hand.
_ The symptoms developed during the further progress of this expe-
riment with globules administered every three or four days until June
6th, were either precisely similar to thos« already related or in the
highest degree analogous. They generally appeared in from six to
seven hours after the dose, lasted from nine to ten hours, and even
manifested themselves the subsequent day in feeble repetitions.
19. — Second Proving with the Third Dilution.
Caroline Ph., aet. 24, of a lively disposition, strong constitution,
brown hair and grey eyes, took the same doses as her sister, and had in
every respect similar symptoms. She had, however, more frequently
than her sister, isolated deep stitches as if from a needle, sometimes in
the left sometimes in the right flank, apparently connected with the
ovaries. Neither of them experienced any other symptom connected
with the genital system.
20. — GersleVs Proving.
Dr. Heinkich Gekstel, aet. 38, phlegmatico-sanguineous tempera-
ment, stout, full-blooded constitution, the father of healthy children, had
never been very sick since his sixth year, when he had the hooping-
cough violently. He is rather disposed to dyspeptic difficulties, cramp
in the stomach, and diarrhoea (after taking cold in the feet), besides
slight rheumatism, frequent palpitations and moderate hemorrhoidal
* The italics indicate those symptoms which we attribute with confidence
to the Colocynth. — Watzke.
GersteVs Provings (22). 317
Weeding every four to eight weeks. He has also been affected for
several years with a torpid sensibility of the whole right side of the
body, appearing clearly only after mental emotions. This most scrupu-
lous observer, and of all our provers the obtainer of the most copious
symptoms, instituted six experiments.
21. — First Proving with the Tincture.
1842, Nov. 20th, 4.30 p.m. Fifteen drops of the tincture of Colo-
cynth, an hour and a half after a moderate dinner. The following
symptoms all appeared within an hour and a half, mostly when seated.
A few minutes after the dose, a slow stitch on the right side beneath
the navel ; soon afterward on the left side of the navel, colic only per-
ceptible when walking, disappearing when standing still, and even on
violent agitation (as in going down stairs), but immediately becoming
very perceptible again on walking on a level ; drawing in the upper
teeth of the right side, with feeling as if the upper lip was swollen ;
constant ringing in the right ear; slight flatulent inflation of the
epigastric region, with pulsation in the small of the back, ameliorated
by the emission of flatulence: general hot flush, especially in the face,
with sweat on the forehead ; compressive squeezing around the middle
of the left leg as if from a narrow ribbon ; copious discharge of flatulence.
22. — Second Proving with the Tincture.
Nov. 22d. Twenty-Jive drops of the tincture in the morning fasting,
after his normal evacuation.
Soon after the dose, rumbling in the abdomen and deep seated pul-
sation in it when lying down, not perceptible to the hand laid upon it ;
sticking in the pubic region ; transitory tickling itching on the thigh,
and the same repeatedly in the face, shoulders, flanks, as well as on the
point of the glans, with urging to urinate. On rising up, empty eruc-
tations. Feeling of numbness longitudinally along the external side of
the right calf as though in the track of a nerve. This feeling increased
in extent as if the nerve were swollen in its periphery, passed gradually
into a dull pressing constrictive sensation and slowly disappeared. Soon
afterward, the same feeling on the dorsum of the first joint of the great
toe of the same side, and a similar but weaker sensation under the nail
of the left great toe. Constrictive pressing in the dorsum and ancle of
the left foot and in the right upper arm. Repeated urging to urinate.
All these symptoms appeared in the course of an hour while quietly
lying in bed. Half an hour later he perceived : griping in the hypo-
gastrium, going off in a stitch towards the left pubic region, with
rumbling and sensation of inflation ; immediately afterward, dulness of
the right side of the head, especially in the temple ; numbness of the
right ' fore-arm ; dull stitches in the left leg; yawning; lassitude
copious urination.
318 Colocynthis.
23. — Third Proving with the Tincture.
Nov. 23d. Forty drops of the tincture at 7 a.m., fasting.*
A tearing in the left side of the nape, which he had experienced
yesterday before taking the Colocynth, and which was aggravated
during the action of the drug and afterward entirely disappeared,
becomes again excited. Sticking pressure in various parts of the body.
Some swelling of the abdomen about the navel, accompanied by slight
dulness of the head in the forehead and temples, and a return of the
vexatious thought which he had forgotten, but which soon yielded to an un-
usual cheerfulness (curative effect? Gerstel). Sensitiveness of the incisor
teeth ; tickling itching on the right arm, disappearing on scratching ;
empty eructations ; unusual thirst ; burning in the urethra after urinating ;
burning and excoriated pain, with moisture, at the anus, as if after a
diarrhoea, and stitches in the rectum.
24. — Fourth Proving with the Tincture.
Nov. 23d. Twenty-three drops of the tincture at 11 p.m., just before
going to bed.
Immediately afterward, pain in the vertex and left eye, as if a nervous
pressure {} Ed. Oest. Zeit.); colic with violent rumbling, as if from the
bursting of large bubbles; copious discharge of flatulence; drawing
twitching with dull throbbing in the left iliac region, and in the right
loin over the crista ilii towards the buttock ; pain as though pressure
were made upon both eyeballs from above downwards; burning of the
under lip ; prickling in the end of the glans ; feeling as if from an
incipient catarrh ; heat, especially in the upper part of the body.
He fell asleep about half an hour after the dose. Once when he
awoke in the night, he felt an unusual warmth over the whole body,
but especially in the lower limbs.
Nov. 24th. In the morning, soon after waking, sticking drawing
pains, now here now there. The usual normal stool was soon followed
by one of pappy consistence and subsequent burning in the anus, and
at the same time prickling in the orifice of the urethra after urinating.
Towards noon, colic appearing only when walking, disappearing every
time he stood still. The pain, arising from the epigastric region extended
when it became more severe upwards towards the chest, and became
then constrictive ; it was sensibly aggravated by every shock, violent
hawking and the like. The bowels were painful on strong pressure on
the abdomen, as if excoriated ; unusual thirst; another pappy stool.
Soon after dinner, when walking in the open air, oozing at the anus
and discharge of moisture from the rectum instead of the expected
flatulence. The oozing continued the whoje afternoon ; at 6 p.m. another
* A quarter of an hour earlier, he had a slight fit of vexation which how-
ever, soon gave place to a peaceful state of mind. Breakfast 'an hour after
the dose, as usual of cold uncooked milk; at noon, plain food and water' the
prover's only beverage now as ever. — Watzke.
GersteVs Provings (25). 319
pappy stool, with much mucus, and subsequent burning at the anus.
The sensitiveness of the abdomen continued all the evening, accompanied
by thirst and early sleepiness while reading an interesting work. At
night, very sound sleep.
Nov. 25. Dulness of the head early in the morning, especially in
the frontal region, with unusual weakness of the memory; normal
evacuation. The frontal headache returned in the forenoon when walk-
ing. Towards noon, after violent exercise, the colic in the epigastric
region of yesterday returned, but less violent, accompanied by dull pain
in the right temple, aggravated by treading and gloomy mood. Finally,
violent feeling of heat rising from the abdomen towards the chest, ending
in partial sweat upon the abdomen and chest, with prickling and oozing
from the anus, and a very copious discharge of urine.
Nov. 26 and 27. Some slight intimations of colic were perceived,
principally about noon, on both these days.
25. — Fifth Proving with the Tincture.
Dec. 8. Sixty drops of the tincture at 7 a. m. The weather was
moist and cloudy; he had had for two days some catarrh, with swelling
of the right alu nasi.
Immediately after the dose : transitory pressing in the right eyelid ;
moderate pinching in the epigastric region ; nauseous, bitter taste ; empty
eructations (frequently returning) ; dryness of the throat and hard palate,
as though the parts stuck together ; sensation in the pharynx and soft
palate, compounded of roughness and burning, continuing until afternoon ;
constant hemming ; the mucus raised had the bitter taste of the drug.
Dulness of the left side of the head, with pressing, burning pain in the
left orbit, temple and nose, on the dorsum nasi and in the superior teeth ;
it seemed as if the eye and nose were swelling and becoming longer ;
(these symptoms were clearly marked and lasting.) Stitches above the
right eye, accompanied by itching of the scalp ; sensation of obstruction
before the left ear; pressing outwards in the right side of the abdomen ;
clucking in the left buttock ; urging to urinate.
Soon after breakfast, when walking rather rapidly: symptoms of ver-
tigo ; dulness of the head in the frontal region ; constriction and
pressing in the left malar bone, extending into the left eye ; pleasant feel-
ing of w r armth in the abdomen, which constantly increases and ends in
griping, but disappears again while walking, with sweat upon the chest
and abdomen. Burning upon the tip of the tongue, continuing for several
hours. Slight burning and moisture at the anus, as if after diarrhoea.
A prickling stitch darts like an electrical spark from the point of the
glans through the abdomen towards the left flank, where it was per-
ceived, and vanished in the same moment.
Towards noon, when walking, symptoms of colic, with inflation of the
abdomen (the cluthes became too tight). Immediately after dinner, a
pappy stool, with horripilation over the head and back ; soon afterwards,
(when lying down,) pain and rumbling in the abdemen, with urging to
x
320 ColocyntMs.
stool and horripilation over the whole body; half an hour later, a watery
stool, with griping, followed by continued and almost irresistible tenesmus.
He became exceedingly sensitive to the damp weather; his legs were
unusually weak ; it was hard work going up stairs. He was' somewhat
confused by the beer drunk in the evening; before midnight, during a
restless dozing, voluptuous dreams and a pollution, during which he
awoke; on waking, tearing in the left tibia and ancle. Sleep after mid-
night undisturbed.
Dec. 9. This morning, empty eructations ; stool soft, pappy, leav-
ing behind tickling in the rectum ; subsequently, sensation of a ball as
large as the fist rising up in the pharynx, with oppressed respiration. In
the afternoon, continued sensitiveness, and griping and commotion in the
abdomen for several hours. Another pappy stool after eating, with sub-
sequent burning at the anus, and cramp in the left calf.
(Dec. 8 and 9. Fluent coryza, constant and uncommonly violent,
with constant dropping from the nose, worse in the open air than in the
room.)
Exceedingly increased sexual impulse for several days.
26. — Sixth Proving with the Tincture.
Dec. 26. Eighty drops of the tincture at 5.30 a. m., fasting.
Empty eructations, frequently repeated during the following symptoms
and sometimes amounting almost to sobbing ; disgust, accompanied by
scraping in the throat ; the disgust disappeared after drinking a glass
of water, but the scraping continued. Compressive sensation in the
epigastrium, returning at short intermissions, and passing into a sharp
pinching, accompanied by slight dulness of the sinciput ; constant roar-
ing and throbbing in both ears, especially in the left ; pulsation in the
whole body, most perceptible in the back and left side of the chest ; pal-
pitations. Itching in different spots, especially on the left side of the
body, which smart like burning points. Prickling in the region of the
right cheek-bone, as though an eruption were coming out. Exceedingly
painful sticking burning on the edge of the left upper eyelid. Sneezing.
Pressing and dull throbbing in the left temple, with a similar sensation
about the left shoulder-joint, with itching of the scalp ; tooth-ache on the
left side, roaring and feeling of obstruction in the left ear, regularly going
and returning; the roaring soon changed to singing ; the pressure on
the temple grew gradually acute and cutting. Troublesome pressure in
the left side of the nape, increased by turning, as in rheumatism. Draw-
ing in the lower incisors. Twitching pain from the left lower molars
into the left arm as far as the elbow.
Aching in the region of the left sacro-iliac commissure, accompanied
by crawling in the whole left sole as though it were asleep ; paralytic
pressing in the whole of the left arm, and fine sticking in the skin of the
back of the hand. As the sensation (as if asleep) in the left foot began
to decrease, the same feeling came on in the right. This was accompanied
by persistent pressing in^the right malar bone and eye ; heat and swelled
GersteVs Provings (26). 321
feeling m the roots of the right lower teeth; a similar sensation of swell-
ing in the arms. At the same time, heaviness and stupor of the sinci-
put ; intimations of vertigo and nausea ; burning on the anterior sur-
face of the tongue ; urgency to urinate.
All these symptoms came on in the course of an hour and a half, while
seated and quietly employed.
Pain in the bowels immediately on talcing only a few steps in the
room, and excitement of the tooth-ache on the right side. Immediately
thereafter, when seated, pressing inwards and dull throbbing in the rio-ht
lumbar region, palpitations, feeling in the right foot as if asleep, pulsa-
tion in the left popliteal space, rumbling in the abdomen, flying pains
in the left side of the epigastrium, burning at the anus. Subsequently,
constant crawling and itching, compelling him to scratch, on the whole left
side of the head ; continuance of the tooth-ache on the right side ; dul-
ness in the forehead ; feeling of warmth in the right ear ; burnino- on
the forepart of the tongue; burning and feeling of swelling of the under
lip ; scraping and burning in the throat and on the hard palate (as if
from pepper) ; frequent erections.
Five hours after taking the dose, urgent inclination to stool, almost
irresistible ; and, in quick succession, two abundant, first pappy, then
fluid evacuations, with ulcerative pain in the boioels, ameliorated by bend-
ing forwards, aggravated by an upright position. Frequent yawning;
weariness of the thighs, especially perceptible when going up stairs ; the
legs feel as if asleep ; moisture at the anus and perinceum. The burn-
ing on the point of tho tongue continued, and a corresponding burning
pain was felt in the stomach, even when eating.
Chills after eating, especially in the upper arms, as if at the commence-
ment of a catarrh, and repeated yawning. The pain in the stomach
and tongue, and the eructations, continued all day and greiu worse to-
wards evening, when another yellow, pappy stool took place, accompanied
by colic. The abdomen continued tender and inflated even after the
evacuation. Little appetite at noon, none in the evening. Frequent
urination.
Dec. 27. In the morning, pressing spasmodic pain in the stomach,
rising up into the throat; sensation as of a foreign body in the throat,
as though he had to swallow over a lump ; pappy, but otherwise normal
stool.
The burning on the tongue, and the eructations, continued the whole
day, but less intense than yesterday. The moisture in the perineum
continued during the forenoon. Absence of appetite in the evening,
with sensitiveness of the borders of the tongue when eating. Nausea
and malaise after eating, as though from indigestion. (Puis, was taken
for this.) Sleep disturbed by frequent waking.
Dec. 28. No more pain in the stomach early ; moderate appetite
at noon. Burning on the tongue and in the stomach again, however,
towards evening, without cause ; empty eructations, with burning in the
pharynx ; twitching in the region of the fifth and sixth left ribs ; pain
in all the upper teeth ; fine sticking and drawing, varying in intensity
322 Colocynthis.
with aching in the left orbit, and burning as if from pepper in the mouth,
especially on the hard palate.
Subsequently, sensation as of a hank in the stomach and pharynx ;
sobbing eructations ; salt taste of the mucus hawked up ; burning in
the stomach ; pressing in the abdomen ; discharge of much flatulence ;
prickling and crawling on different parts of the body ; feeling of numbness,
swelling and heat in the left foot, which gradually encroaches upon the
"whole leg, with itching and tickling, and lasts fur a considerable time.
Pressing throbbing pain on the upper part of the inner side of the right
leg, extending to the posterior side of the thigh upwards towards the
ischium (when sitting and walking).
Dec. 31. The scalded feeling at the tip of the tongue, the gastric
troubles, the occasional eructations, the diminished appetite and depres-
sion of spirits continued, with evening exacerbations during the 29th, 30th
and 31st. To them was then added a frequently repeated throbbing,
finally twitching pain in the right upper arm in the region of the inser-
tion of the deltoid, whence it extended through the shoulder towards
the upper teeth, and as far as the region of the temples and vertex. The
pain was in the periosteum, and after it had frequently returned, the
muscular parts of the arm there became paiuful, as if sore, to pressure.
Every exacerbation of the symptoms, without exception, began with
the burning at the apex of the tongue. The gastric pains were always
accompanied by pains in the face and teeth. It was particularly ob-
served that the symptoms appeared in groups, and were aggravated in
the evening and during rest.
27. — Hausmanri's Proving with the Tincture.
Nov. 8. Dr. Franz Hausmann, one of our most resolute Colocynth
provers, began his experiments with a dose of thirty drops of the tincture.
After the lapse of six hours, the symptoms appeared in the following
order. Continual tensive pain in the bowels; it seems as if they were
gathered together into a ball, had fallen down, and were lying like a
heavy weight in the hypcgastrium ; it appears as if the anterior parietes
of the abdomen were wanting, and the bowels were in danger of falling
out. Occasional pressing at the anus, as though a quantity of faeces
were about to be discharged, with the escape of only a little mucus. Dif-
fusion of a genial warmth, which seemed to deprive the limbs of strength.
Weakness of all the joints, especially of the knee and elbow. Disinclined
to exertion of either body or mind, even to visiting his nearest friend.
Pressing pain in the right hypochondrium, at the arch of the diaphragm,
oppressing the respiration.
Nov. 10. Having had no symptoms on the 9th, Hausmann took
half a drachm of the tincture on the 10th at 1 2. 1 ,- p. m.
Half an hour afterwards, a violent pressure suddenly set in upon the
bladder, which was full, but as rapidly passed off on the expulsion of
considerable flatus in rapid succession, which drove before it some mucous
ffausmanri's Provings (27). 323
fluid. _ These turns of flatus frequently returned in alternation with the
following symptoms :
Movements as if from the breaking of large bubbles in various parts
of the abdomen ; frequent pressure at the anal sphincter, which ceased
at once on the escape of the slightest quantity of wind or mucus;
pressing and tension in the occiput, most sensible at the inferior lateral
protuberances.
Nov. 11. A very slippery soft stool at about 11 a.m. ; tensive pres-
sure over the whole forehead on its evacuation. The same symptoms
returned in the afternoon, succeeded by pressure upon the bladder, alter-
nating with pressure upon the anal sphincter. Finally, entire relaxa-
tion of the most remarkable degree, for a whole hour, during which he
was entirely unfitted for either bodily or mental labor. The spasmodic
yawnings constantly return.
Nov. 12. Both the last mentioned symptoms were repeated about
the middle of the forenoon. A sudden shock, from behind forwards,
passed rapidly through the hepatic region, and then in the same direc-
tion through the head. Sensation at the anus, as if successive slippery
bubbles were escaping. "When walking, discharge of copious flatulence,
causing the rectum to vibrate.*
Nov. 14. Hausmann took a drachm of the tincture in the fore-
noon.
At about half-past eleven, frequent eructations. At noon, a soft, fluid,
rapidly discharged stool, after a continual gentle pressure and the pas-
sage of a quantity of slippery flatus. At one p.m., a pressive pain in
the left side of the forehead, occasionally slightly vibrating ; it was
clearly traceable in an arch which defined the lateral and superior bound-
aries of the left frontal sinus.
Towards four p.m., first griping (drawing hither and thither) in the
umbilical region, gradually subsiding again, then returning and rapidly
passing into cutting as if from a large chisel, which was thrust deep into
the epigastrium, thence passing in a curve backwards and downwards
into the pelvis, and thence cutting its way upwards again.
At half-past four, the cutting in the hypogastrium several times took
the direction from behind forwards and upwards, and was every time
relieved by a forcible discharge of flatus. It was also relieved by strain-
ing and the consequent expulsion of a long train of slippery bubbles of
wind, and a small quantity of bland mucus. It returned in the same
fashion at intervals of from five to fifteen minutes. Finally, towards five
p. m., after such an interval, a very painful expulsive pressure, and in a
short time, a quantity of thin faeces passed involuntarily through the
sphincter, at a single impulse. It was perfectly bland, causing not the
slightest burning nor smarting at the anus, which was rather protected
all about by the slippery mucus, of which a great portion of the passage
* We do not interfere with our colleague's mode of expression; it has at any
rate the great merit that, besides its originality, it is exceedingly clear and
concise. — Ed. Oest. Zeit.
324: Colocynthis.
consisted. The pains in the abdomen all disappeared with this dis-
charge.
Towards 8 p.m., when in pleasant society, violent, long continued pres-
sure in the lateral occipital protuberances.
-At night a succession of light, imaginative, pleasant dreams. Waking
after midnight, he perceived, as he lay on the right side, pressure and
weight in the left side of the forehead, which felt otherwise well. The left
eyelid lay thick and heavy upon the ball, which seemed as though
squeezed from before and above. A slight throbbing like a pulse in
the left hypochondrium, at the summit of the diaphragmatic arch.
Nov. 15. Shortly after rising, easy discharge of inodorous flatus,
sometimes silent, at others noisy ; head befogged ; difficulty in collect-
ing his thoughts ; no inclination to search after and grasp objects of
interest. A slight exertion in walking fatigued him, and produced a
gentle perspiration, which made his limbs feel weak, and ended in sweat;
if he stood still, the air, though far from raw, struck through him, in
spite of his being warmly clothed, like a cold drizzle.
He had no further stool until the afternoon, when it was of its usual
consistence, and passed easily and smoothly. (The same peculiarity
attended the evacuations of the following days.) Long and close suc-
cessions of smoothly discharged bubbles of inodorous gas passed the
sphincter at longer or shorter intervals ; a symptom which returned for
several days.
Nov. 10. Towards noon, when walking, drawing and tension in the
interior of the right knee-joint, disappearing and recurring several times ;
painful tension in the right shoulder on first walking, continuing and
becoming worse from using the arm. At half-past twelve, tensive and
pressing pain in both sides where the diaphragm is attached.
Nov. 17. Mist before the right eye early in the morning, lasting
several hours, and not removed by rubbing it.
Nov. 1 8. Frequent, long continued and violent ringing in the ears ;
sexual impulse highly excited.
Nov. 19. At ten a.m., shimmering before the right eye, in the shape
of a circle with rays, coming on a short time after getting up from writ-
ing. Previously, tension over the forehead while evacuating a very soft
and smoothly passed stool. Tension over the chest under similar cir-
cumstances in the afternoon. Aching in the right eyeball in the even-
ing, upward and outward, aggravated by rubbing it with the finger; it
feels harder than usual there. This aching lasted some days.
28. — Hausmanrts further Proving with the Tincture.
1843, June 7. Seven months after his previous experiments, Haus-
mann began again by taking one hundred drops of a very concentrated
tincture, at about 1 p.m.
At six p.m., he experienced, when walking, an unpleasant sensation
about the navel, as if after taking cold, with urging to stool, which he
Hausmann *s Provings (28). 325
was obliged immediately to attend to, as the sphincter showed no re-
sisting power. The discharge was thin, orange-colored and pappy.
After walking for half an hour, a renewed and increased sensation about
the navel, as though he had been chilled ; more violent tenesmus, to
which he was obliged hastily to give way, with a result similar to the
former. On bending over to examine it, a warm perspiration broke out
over his whole face, followed by a bitterish eructation from the stomach.
On walking further, a warm moisture overspread the whole body, and
he became weak ; abdomen inflated and teuso.
After a quarter of an hour, during which he was incessantly walk-
ing, the same unpleasant sensation was renewed below the navel, with
still greater violence. It increased to a drawing catting, which darted
repeatedly from behind forwards and upwards in a curve to the navel.
This ceased on the occurrence of urging to stool, which became exeeed-
ingly pressing, and the evacuation ran in a watery stream out of the
sphincter, which seemed paralyzed ; it contained part of the contents of
the soup eaten at the noon meal, still undigested. There was then in-
effectual urging, which, when repressed by an effort of the voluntary
muscles, gave rise to a pressing tension in the lowest part of the abdom-
inal parietes, and an acute pressure at the inferior angle of the right
scapula, with tensive pain extending thence downwards. On the cessa-
tion of the long continued tenesmus, a free, protracted discharge took
place, the sphincter standing wide open as if paralyzed ; at the same time,
burning in the orifice of the urethra on the passage of the last few
drops. Frequent, for the most part empty, eructations on rising from
the stool. The sitting posture was easy, and ameliorated all the pains.
After a considerable interval, during which he had remained for the
most part seated, an urging to stool without the preceding colic, which,
nevertheless, on the third or fourth repetition, took away all command
of the sphincter.
A little before, (while seated,) a great, white, very bright light was
seen at the side of and below the right eye ; but as he turned his eyes
rapidly sideways in order to examine it, it vanished.
Notwithstanding the occurrence of all these powerful effects of Colo-
cynth upon the prover, his tongue remained constantly clean, and his
inclination for food was not diminished, but rather increased.*
Dr. Hausmann is thirty years old, of a strong constitution, and san-
guineous temperament. His health has never been interrupted for any
length of time. Two attacks of fever, the consequence of violent men-
tal exertion under unfavorable conditions, ceased in three days with the
usual copious critical evacuations. He has twice spit blood after im-
moderate long continued exercise, but experienced no further evil con-
* In an appendix to liis experiments, Hausmann states that he once took
Colocynth in the evening, immediately before going to sleep. (He does not
say how mnch he took.) In the morning early, on going out, the first colic
pa'ins came on, but disappeared after taking a cup of coffee. At the first step
he took afterwards, however, so violent a tenesmus came on as instantly to
deprive him of all power over the sphincter. — Watzke.
326 Colocynthis.
sequences. He has now been for a long time perfectly well in every
part of his system.
29. — Maschauer 's Proving with the Tincture.
Dr. Karl Maschauer, 28 years old, of a scrofulous constitution,
delicate build, and phlegmatic temperament, showed but little sensibility
to the action of of Colocynth, and experimented with doses far too small
to affect so insensible a system.
1842, Nov. 7. He began by taking five drops of the tincture in the
forenoon, in a little water. Two hours afterwards, he felt some con-
striction in the chest, and subsequently stitches in the upper part of the
left half of the chest, especially when walking.
Nov. 8. Five drops in the forenoon, and a similar quantity five
hours afterwards, but without result.
Nov. 9, 10. Five drops w r ere taken morning and evening. Move-
ments in the bowels, with oppression of the chest, came on each time
two hours after the dose.
Nov. 11. Ten drops in the forenoon, caused, soon after taking them,
constriction of the chest and empty eructations, which lasted almost the
whole day.
Nov. 12, 13. Fifteen drops each day. In half an hour, empty
eructations, and in two hours, griping in the abdomen, with discharge of
flatulence both upward and downward, followed by a thin stool and
relief of the pains. Twenty drops taken on the following day produced
no other effect than violent eructation (immediately) ; griping and rum-
bling in the bowels (after four hours) ; and (two hours afterwards) two
pappy stools, with discharge of flatulence.
30. — Second Proving with the Tincture.
Nov. 20. Fifteen drops. Constrictive sensation, with flying stitches
in the chest, beginning soon after the dose, and troubling him all day,
especially when walking.
Nov. 21. Twenty drops. Griping about the navel, with discharge of
much flatulence (after five hours).
Nov. 22 to 25. Twenty-five drops every morning at eight o'clock.
The few results obtained were the same as before. Oppression of the
ehest (soon after eating) ; six hours later, violent griping, rumbling and
cutting around the navel, with discharge of flatulence, and after four
hours more, a pappy stool.
Nov. 26. Thirty drops, taken in the forenoon, only sufficed to de-
velop a few traces of a drug- disease, and principally subjectively, in the
torpid organism of the prover. Violent griping and cutting about the
navel (after six hours), increasing from hour to hour; the abdomen
tense, inflated painfully, sensitive to the touch ; some diminution of the
pains after two watery stools ; during the night, great restlessness and
Reisinger's Proving (33). 327
sensibility of the abdomen, so that he could scarcely bear the lightest
pressure upon it. The sensibility of the abdomen continued the fol-
lowing day.
Nov. 28, 29. A similar dose was followed by similar symptoms, but
in a less degree.
31. — Third Proving with the First Dilution (1-10).
Dec. 1 to 14. Maschauer made a third proving with the first (deci-
mal) dilution, continuing it for fourteen days, but with no result. On
the first day he took five drops and increased the dose each day by five
more, without experiencing the slightest abnormal sensation.
The prover made no change in his very simple and regular course of
living during the proving.
32. — Puffer's Proving ivith the Third Dilution.
The experiments of Dr. Franz Puffer, who is of a venous-lymphatic,
phlegmatic-bilious temperament, forty years old, and one of our most
timid provers, deserve mention, as we trust he will agree with us in saying,
as they afford some evidence that the Colocynth will act, even in dilu-
tions, upon a tender bowel.
He took for six days in succession, at about noon, four or five drops
of the third dilution of Colocynth tincture.
Immediately after the dose, bitter taste in the mouth, and bitter
eructations ; an hour later, rumbling in the abdomen and excitement, as
if diarrhoea were about to come on, with discharge, however, of only
some fetid flatulence. The subsequent stool was hard and unsatisfac-
tory. On one occasion, the evacuation, which began knotty and dry,
ended in a diarrhoea. Sleep interrupted by lively dreams and frequent
call to urinate; urine remarkably increased.
33. — Reisinger's Proving of the Tincture.
Dr. Edward Reisinger, 30 years old, strong, thick-set and phleg-
matic, has enjoyed good health for a long period. His experiments
present few improvements upon those of his two predecessors. He be-
gan with ten drops of the tincture, gradually increased the dose to
twenty-five, and then declined again to the first trituration of the drug.
1843, Nov. 3, 4, 5. Ten drops, morning and evening. Stiffness of
the right forearm, with painfulness of the extensors. On the evening of
the 5th, no symptom. This feeling continued the next day.
Nov. 6. Fifteen drops in the morning. After five hours, griping
and cutting in the umbilical region ; discharge of fetid flatulence, and a
soft evacuation. The colic did not cease after the evacuation, but be-
came aggravated, and accompanied by a chilly feeling over the whole
body.
328 Colocynthis.
Nov. 7, 8, 10, 11. Fifteen drops on the first day, and twenty drops
on each of the subsequent days, were followed by nothing but eructa-
tions, griping and flatulence.
Nov. 12. Twenty- fin drops. After five hours, violent rumbling,
with very severe cutting in the left hypochondriac and umbilical region,
and three very soft brown stools. The colic pains continued this time
all day, and were not removed as on former occasions, after taking black
coffee or warm soup.
Nov. 13. Twenty drops, in the morning. Toward noon, slight
drawing in the right upper arm, remarkably increasing after dinner, and
becoming almost painful, but decreasing again when walking in the
open air. No remains of colic the next day.
Nov. 14. Fifteen drops. Drawing in the right upper arm the
whole day ; towards evening, slight griping and a pappy stool, with burn-
ing at the anus ; feeling of coldness in the whole body, succeeded by
heat without thirst. The drawing in the arm continued into the next
forenoon.
Nov. 19, 20. Five grains of the first trituration (\ to 9). No symp-
tom on the 19th, but on the 20th, nausea, empty eructations and gri-
ping in the abdomen, with accompanying transitory head-ache in the
left side of the forehead.
We know not whether to regret that our colleague did not experi-
ment with larger doses, or that he did not pursue so promising a pro-
ving with the smaller ones.
34. — RothansVs Proving with the Tincture.
Dr. Joseph Rotiiansl's pharmacodynamic experiments with Colo-
cynth were crowned with the success they deserved. He had to con-
tend against an extreme insusceptibility to the action of the drug.
1842, Nov. 2, 3, 4. No result from four, five and twelve drops of
"the tincture.
Nov. 5. Fourteen drops. Pressing in the scrobiculus and con-
striction of the larynx, obliging him to swallow frequently.
Nov. 6. Sixteen drops. In addition to oppression of the chest and
constriction of the larynx, which lasted all day, pressing in the forehead
and at the root of the nose, as though a violent catarrh were coming
on, continuing for three hours.
Nov. 7, 8, 9. Eighteen drops each day. On the last day, move-
ments in the abdomen and three pappy stools, with feeling of coldness
in the whole body.
Nov. 10, 11, 12. Twenty drops, with no visible traces of effect.
Nov. 19. On this day, however, after taking fifteen drops, violent
colic-like pains emanating from the umbilicus, with frequent discharges
of flatulence, which afforded relief. The pains continued all night, and
deprived him entirely of sleep.
Nov. 20. Constriction of the larynx, disappearing in the open air
(after half an hour) ; sleepless the following night from cramp-like pres-
BothansVs Provings (35). 329
sure in the scrobiculus and constriction of the stomach ; this latter
was so sensitive that he could not endure the pressure of the lightest
covering.
Nov. 21. Towards morning, loud rumbling in the abdomen, eructa-
tions and discharges of flatulence, which relieve. Fifteen drops taken
in the foreuoon ; tensive head-ache in the right temple ; single, rapidly
passing stitches in the left flank. In the afternoon, cutting and thump-
ing in the abdomen ; abundant discharge of flatulence, which affords
relief; diarrhceic evacuation. (The stool was of the same consistence
on the two following days.)
Nov. 24. Twenty -five drops. Aching in both temples, aggravated
at first in the open air, then entirely disappearing; feeling of burning
in the left foot along the tibia (when walking) ; constrictive pains about
the navel, in the evening ; constrictive pressure of the larynx.
Nov. 25. Thirty drops. Cutting in the abdomen immediately
after eating ; a diarrhceic stool, with tenesmus.
Nov. 26, 27. Thirty-five drops each day. The same symptoms
continued. The last doses continued their effect over the three following
days, producing colic pains continuing all night between the 21 th and
the 28th, with the most excessive sensibility of the abdomen ; general
lassitude and painful weariness in the small of the back on the 29th,
and pressing head-ache on the morning of the 30th.
35. — Second Proving with Small Doses of Tincture.
Dec. 5, 6. Three drops of the tincture, with no result.
Dec. 7 to 19. With the exception of the 10th, 11th, 15th and 16th,
he took five drops every day, with the following results :
Dec. 7. Great oppression of the chest before midnight, driving
away sleep ; restless sleep after midnight, with vivid, troublesome
dreams.
Dec. 8. Pressive head-ache, early, in the temples, and annoying
twitching of the right upper eyelid ; the last symptom continued during
the three following days. In the evening, movements in the abdomen,
soon followed by a pappy stool ; slight cramp in the stomach, at night,*
rising along the oesophagus into the throat.
Dec. 9. Sudden, rapidly passing vertigo, with darkness before the
eyes, in the evening, on sitting down.
Dec. 13. Rumbling in the abdomen and slight head-ache early in bed ;
at noon, tensive pain in the left thumb, impeding its motion.
Dec. 14. Heaviness in both knees; tearing in the left knee, disap-
pearing when walking, in the evening.
Dec. 15. Repeated tensive pain in the left thumb.
Dec. 16. In the evening, considerable head-ache, and unfitness for
every occupation.
Dec. 17. Eructations (immediately after taking it) ; noon and even-
* See note, ante, p. 311.
330 GolocyntJiis.
ing, slight colic after eating ; extremely restless sleep, with vivid, non-
sensical dreams ; troublesome oppression of the chest.
Dec. 18. In the evening, numbness of the limbs in the knees when
stooping down, so that it was somewhat troublesome to get up again ;
restless night, full of dreams.
Dec. 19. Drawing pains in the right thigh as far down as the knee;
a symptom which continued with nearly equal intensity through the
next three days (20th to 22d).
The intestinal canal was torpid during the whole time while he was
taking from three to five drops, the evacuations were hard, and took
place, contrary to his usual habit, only once in two or three days.
Dec. 23. Ten dropts in the morning. Immediately after dinner,*
rumbling in the abdomen, constrictive pain in the umbilical region, and
a pappy stool ; during the succeeding night, colicky pains, with discharge
of flatulence.
Dec. 26. Five drops each morning, on the 26th, 27th and 28th.
Cutting abdominal pains after dinner and supper.
Dec. 27. Head-ache and sticking in the right patella, commencing
in the morning. In the evening, rumbling in the bowels, cutting around
the navel, and two pappy sleols.
Dec. 28. The sticking in the patella, which was experienced yester-
day, returned ; it comes on when walking, and disappears on continu-
ing to walk. Violent attacks of colic, the two succeeding nights.
Distinct Colocynth symptoms were experienced by the prover, for
four days after he took the last dose; on the 30th and 31st, in the af-
ter part of the day, sticking in the right patella; frequent griping in
the abdomen ; painful cramp in the stomach at night, relieved by eruc-
tations of wind ; restless sleep ; tossing about in bed.
1843, Jan. 1. Eructations early in the morning ; soon afterwards,
vomiting of a bitter-tasting, yellow", serous fluid ; bitter eructations after
dinner ; in the evening, absence of appetite and thirst, violent head-ache,
fluent catarrh and frequent sneezing. Pleasant night's rest.
Jan. 2. The prover was attacked with a regular angina, setting in
with chills, head-ache and burning pain between the shoulders, and was
noHnclined to attribute either the symptoms or the catarrh of the pre-
ceding day to the Colocynth ; he, therefore, took no further account of
his sensations.
Our colleague, whom no one can easily accuse of too strong a phar-
macological faith, or too earnest a lying-in-wait for symptoms,°closes his
memoranda with the following remarks, in which we heartily join:
"I took four hundred and thirty-six drops of Colocvnth in the whole.
My conclusion from the foregoing detail of symptoms," is, that its action
* From the fact that many provers experienced various and particularly
abdominal symptoms immediately after dinner, we may with some probability
infer a direct causal connection between Colocynth and the ingestion of food
but none between the remedy and the time of day. Most of the experiment^
ers took the medicine between 7 and 9 a.m., and Colocynth generally requires
from five to six hours to develop its action. — Ed. Aust. Jour.
WachteVs Proving* (36). 331
is principally directed to the abdominal viscera, and specially to the in-
testinal canal. By far the msot prominent and troublesome symptom
in my case was the colic, which never came on except at night. The
rheumatic pains in the limbs and joints are, however, so much the more
important phenomena, and xoith greater certainty ascribable to the drug,
inasmuch as I had never experienced the like, either before or since. I
am thirty-one years old, of an excitable temperameat and slender build ;
I have always enjoyed good health since passing through the usual dis-
eases of childhood, except in 1832, when I had an attack of cholera,
which kept me for several weeks in a dangerous condition. My man-
ner of life is regular, and presents very rare departures from my usual
course; my diet consists of a moderate amount of meat, and beer as a
beverage."
36. — WachteVs Proving with the Tincture.
Dr. Cajetan Wachtel, thirty odd years old, of a bilious-melancholic
temperament and stout frame, has been uninterruptedly well for years ;
he is an excellent observer, and not the less so because he is perhaps
a little timid as a prover.
1842, Nov. 10. One drop of the tincture taken in half a glass of
water, an hour after a milk breakfast, produced no symptoms.
Nov. 17. Two drops. Dulness of the head for an hour.
Nov. 18. Three drops. No symptoms.
Nov. 19. Four drops in the morning. Griping around tho navel
for some minutes.
Nov. 20. Five drops. In the afternoon, twitching at the anus, and,
soon after, two evacuations of the usual character.
Nov. 21. Five drops, with no special result beyond more copious
urination than ordinary.
Nov. 22. On this day, and the 23d and 24th, ten drops each day.
Soon after the dose, pressing feeling in the orbits, towards the root of
the nose. In the afternoon, feeling of heat in the nape, burning and
twitching in the rectum and at the anus; soon after, three fluid, mu-
cous, but painless stools.
Nov. 23. Feeling of stiffness in the muscles of the nape, when mov-
ing the head ; after dinner, flying stitches in the hepatic region and
sacrum ; in the evening, feeling of dryness in the eyes.
Nov. 24. In the forenoon, urgency to urinate, with discharge of a
great quantity of clear watery urine (returning at pretty near hourly
intervals). In the afternoon, dulness of the head, with pressure in the
orbits ; feeling of coldness over the whole body, especially in the knees,
notwithstanding the room was warm enough; subsequently, ineffectual
pressing in the rectum, soon followed by itching at the anus, and at the
orifice of the urethra. In the evening, uneasiness and weakness of the
whole body, especially of the lower limbs ; canine hunger, with particu-
lar longing for bread and beer.
Nov. 25. Fifteen drops, and the dose was increased five drops each
332 Colocynthis.
day, until the 29th. The symptoms observed were not very character-
istic, and may be summarily staled. Dulness of the head; scraping in
the throat; rumbling in the abdomen; constriction in the umbilical re-
gion ; inflated abdomen ; feeling of emptiness and soreness in the bow-
els; pappy stools with burning at the anus; itching in various parts of
the body, obliging him to scratch; transitory stitches in the hepatic re-
gion, sacrum, dorsum of the right foot, foot-joint and left great toe.
37. — WachteVs Proving with the First Trituration (1 to 9).
The first trituration of Colocynth (10 grains of the pulp to 90 of su-
gar of milk) yielded more abundant and more characteristic symptoms
to this prover than the tincture.
Dec. 20. From this day to the 28th, he took ten grains every
morning. No result on the 20th.
Dec. 21. Nothing but pressure in the forehead.
Dec. 22. Increased secretion of the urine, and towards evening
dulness of the head.
Dec. 23. Transitory drawing sticking in the periosteum of both
bones of the forearm.
Dec. 24. Scraping in the throat in the region of the uvula.
Dec. 25. Throat reddened and swallowing difficult.
Dec. 2G. A true angina set in, for which the prover took bell., and
subsequently lach*
Jan. 3. After the throat affections had subsided, he began again
with the former dose of ten grains of the first trituration, which he
took regularly every day until the 15th. Frequent urging to stool,
without any evacuation.
Jan. 4. The taste of Colocynth seemed, to-day, to be very disgust-
ingly bitter, and continued all night. In the evening, sticking drawing
along the left tibia into the ancle bones, accompanied by burning py-es-
sure in the left eye ; these pains disappeared again in five or six min-
utes. Subsequently, a very hard evacuation, as if he were passing
stones.
Jan. 5. Pressure in both temples, itching in various places in the
skin, exciting constant restlessness, so that he can scarcely remain
seated. At noon, beer tastes remarkably bitter. In the evening,
when walking, sensation as if all his strength tuas failing ; feeling of
emptiness in the stomach, and canine hunger. \ No evacuation the
whole day.
Jan. G. Towards noon, a violent cutting pain, like an electric shock,
darted through the whole abdomen to the anus. Soon after, urging to
* Why did not the prover suffer this apparently drug-sickness to run its na-
tural course ? And instead of a barren name, why does he not give us an accu-
rate description of its symptom*? Can it have been a pure accident, that
three of our provers (Arneth, Rothansl, and \V"a>u iei.) were attacked with
similar throat affections during their provings? — Watzke.
f Compare Waciitel's proving of IS ov. 24, [ante. p. 331.] — Watzke.
Wachtel'' s Provings (37). 333
stool without an evacuation, which appeared an hour afterwards in sin-
gle pieces of a stony hardness. In the afternoon, flying stitches in the
right side of the chest from before backwards. During the whole day,
sensation on the tongue as if it had been scalded with a hot fluid*
Jan. 7. Towards 3 p.m., the feeling of weakness in the whole body
returned, but without the subsequent voracious appetite. Towards
evening, transitory drawing in the upper and lower limbs ; single stitches,
as if from needles, under the left pectoralis. No stool.
Jan. 8. The scalded tongue appeared again, but less severely.
Jan. 9. Drawing aching in the left foot. At noon, extreme sleepi-
ness. After dinner, a sticking cutting pain in the right foot, as if a nail
were driven through.
Jan. 10. Soreness of the skin on the vertex, as though the hair on
this part were constantly dragged upwards.
Jan. 11. The feeling in the scalp continues, and is accompanied by
a drawing, pressing paidjin the occiput. Both symptoms disappeared
towards evening.
Jan. 13. Drawing sticking in the joints of both feet, lasting for a min-
ute, often recurring, a*nd not interfering with walking. It becomes worse
after coffee and wine, and is accompanied by boring pains in the bones
of the lower limbs.
Jan. 14. The above described pains continued the whole day, with
inconsiderable remissions, but in diminished intensity. The upper ex-
tremities were similarly affected in the afternoon.
Jan. 15. Pressive pain in the sacrum, diminished by movement.
While the last massive doses of his first proving had continued to act
for two days only, and that in a very weak and scarce note-worthy de-
gree (want of appetite, <iftling of weakness in the stomach, frequent dis-
charge of flatulence and absence of stool), Wachtel continued to recog-
nize clear and unmistakable drug-symptoms for a full fortnight after he
took his last dose of the first trituration.
Jan. 16. The rheumatic-gouty f pains came on more violently than
ever before, sometimes in the joints and sometimes in the bones of the
upper and lower extremities, but did not last long. In the afternoon,
a drawing aching came on in both shoulders.
Jan. 17. In the evening, in addition to the rheumatic gout of the
day before, heat in the head and palpitations, which continued the next
day in a less degree, and disappeared on the day after.
Jan. 20. In the forenoon, feeling of repletion in the gastric region;
rumbling in the abdomen, with great inflation ; violent colic pains, con-
tinuing for an hour, but disappearing after two evacuations, following
each other in quick succession.
* " I had this feeling in the pharynx also during my angina, and am almost
tempted to believe that it was caused by the Colocynth, and the more so, as I
never before had suffered from sore throat." — Wachtel.
f We repeat that a pfover cannot commit a greater error than in recording
his symptoms by means of the nomenclature of any nosological system, in-
stead of describing them in definite and clear expressions.— Ed. Aicst. Jour.
334 Colocynthis.
Jan 22. Night restless from flying stitches in the hepatic region ;
on the following day, continuous pains in the left knee-joint, impeding
walking.
b. 1. Our colleague was still troubled by his rheumatic gout in
the joints and long bones of both extremities, of greater or less inten-
sity at different times.
38. — Weinke's Proving with the Tincture.
Dr. Franz Karl Weinke, thirty years old, of a sanguineous tempera-
ment, irritable disposition and strong constitution, made several pretty
energetic provings with Colocynth. He has an excellent appetite on
taking a good deal of exercise in the open air, his feet perspire summer
and winter, which he does all over from slight causes ; subject to catarrhs,
not strict in his diet, but capable of disposing of considerable quantities
of wine and beer without injury. He is one o|^he provers who carried
his experiments on to the production of a A^rroble drug sickness.
1842, Nov. 19. Twelve drops of the tincture in water, at half-past
ten, a.m., after a half hour's walk in the open air. An hour afterwards,
while writing, he perceived in the dorsum of the right foot, more on the
left side towards the great toe, a painful pressure, with slight numbness
of the right leg ; the whole was less perceptible when walking, and spon-
taneously disappeared after a quarter of an hour. Fifteen drops were
taken at a quarter after ten, in the same forenoon. In the afternoon, to-
wards 3 o'clock, he had a pappy evacuation, followed by slight, intermit-
ting griping, accompanied by a feeling of having taken cold in the umbili-
cal region, and rumbling in the bowels. Subsequently, transitory stitches
in the left side of the chest; moderate flatulj*ttc,y. At 7 p. m., a semi-
fluid stool, accompanied by a perfect storm offlatulence, and followed
by considerable discharge of wind. The unpleasant feeling, such as is
experienced from catching cold at night in the bowels and feet, and hav-
ing a diarrhoea in the morning in consequence, continued the whole af-
ternoon.
Nov. 23. Twenty drops of the tincture taken at half-past ten a. m. In
half an hour, rumbling in the abdomen, feeling as of taking cold in the
same, and two semi-fluid stools. In the afternoon, lassitude, notwith-
standing which, excited sexual impulse.
Nov. 30. Sixty drops of the tincture in half a glass of water, at
about half-past ten, a.m. Shortly afterwards, transitory stitches in the
left half of the chest; feeling as of taking cold, and slight rumbling in the
abdomen. At a quarter before twelve, pressure in the dorsum of the
right foot, extending towards the left to the great toe. At noon,
an enormous appetite. At 2, p. m., sudden tenesmus, soon followed by
a copious pappy evacuation, succeeded by griping, aud sensation as if
taking cold in the abdomen,* sleepiness, disinclination to study. At 4,
p. m , another diarrhceic stool, with subsequent flatulence, and disa-
* The evacuations were followecl, in most of the provings, not by an aggra-
vation, but by an amelioration of the abdominal symptoms. — Ed. Aust. Jour.
WurstVs Provings (39). 335
greeable though not a very remarkable or excessive feelino- of general
debility. ° 6
As Weixke was exceedingly inconvenienced by the very marked
action of Colocynth upon his lower extremities, especially when walk-
ing, he discontinued the experiment. The symptoms which he expe-
rienced during the three following weeks may be summed up as fol-
lows : Heavy sleep, full of dreams ; dulness in the morning, with late
waking and dislike to get up; heaviness of the loiver limbs; increase
in size of both feet, so that all his boots were too small in the instep.
A constant dull-pressing, cramp-like pain, as if in the periosteum, on the
dorsum of the right foot, in the scaphoid and internal cuneiform bones ;
the skin was not discolored nor tense over the painful spot ; a swelling
on the right edge of the tarsus, soft, pale, painless, clearly circumscrib-
ed, and as large as a pigeon's egg, appearing like a common lymphatic
tumor. The same pains in the left foot as in the right, and in the
same spot, (sometimes, also, in the second joint of the great toe,) but
less severe, and accompanied by no swelling.
These symptoms were somewhat ameliorated while walking, but were
always perceived in the evening, after considerable exertion, and then
connected with indescribable weariness in the lower extremities. As
long as these phenomena lasted, the bowels were sluggish, acting only
every other day, but not particularly hard ; constant flatulency, urine
apparently rather diminished. Black coffee never removed the above
detailed symptoms. The circumscribed swelling on the foot was still
present after the lapse of six months.
39. — WurstVs First Proving with the Tincture.
The three provings of our colleague, Dr. J. P. Wurstl, lose a little
of their positive value in one point of view, from the fact that he had
formerly frequently experienced the same symptoms, gouty-rheumatic
pains, toothache, diarrhoea, <fec, as he suffered while takino- the Colo-
cynth ; but, on the other hand, they are a little remarkable from the
fact that the drug proved a specific for those ailments, which have never
since troubled him in the least. He is 39 years old, of a sanguineous
temperament, and of tolerably strong constitution.
1842, Nov. 1. One drop of the tincture in the evening; soon after
which, much flatulence, with tension of the abdomen.
Nov. 2 and 3. One drop morning and evening. Violent pain in a
hollow tooth ; feeling of coldness in the stomach; rumbling in the bow-
els ; great looseness.
Nov. 4. Two drops morning and evening. Fulness in the abdo-
men ; discharge of much flatulence.
Nov. 5. Two drops in the morning. Sudden sticking pain in the
forehead, towards the nose ; frequent sneezings, with dryness in the
nose. The sticking ceased after a quarter of an hour, and the whole
head became dull for an hour.
Nov. 6 to 11. Three drops night and morning the first two days,
Y
336 Colocynthis.
four drops the next two, and five drops the last two. Stiffness in the
left knee when sitting, disappearing when walking, yet frequently re-
curring ; discharge of a great deal of offensive flatulence.
Nov. 11 to 13. Six drops on the first two days, morning and even-
ing; on the third day in the morning only. Dulness and heaviness of
the head, with feeling as if a catarrh were coming on ; slight vertigo in
the evening.
Nov. 14. Seven drops in the morning ; eight drops in the evening.
Frequently recurring vertigo, with dulness of the head. All the
symptoms came on, generally, half an hour after taking the drug, and
disappeared after from six to seven hours.
Nov. 15. No more medicine; the symptoms however continued.
Sudden cramp-pain in the right great toe, in the evening, extending
towards the metatarsus ; waking accidentally in the night, he found the
whole right foot, especially the metatarsus, swollen ; this continued the
whole of the next day, but was only painful when stepping on it or
making strong pressure.
Nov. IV. The pain and swelling notably diminished; he can tread
now with care, but the affection did not disappear until the 19th.
40. — Second Proving with the Tincture.
Nov. 25. Six drops in the morning. Pressive headache in the
frontal region, after half an hour ; tension in the abdomen ; discharge
of much flatulence ; two stools ; copious urine.
Nov. 26. Six drops. More violent headache than yesterday, after
one hour; cramp-pain in the second toe of the right foot, extending to-
wards the metatarsus, after two hours. The headache returned fre-
quently the next day, but never remained long at a time.
Nov. 28. Eight drops in the morning. Great tension in the abdo-
men, with violent rumbling ; copious urine ; threatening of cramp-
pain, alternately in the right second toe, and in both knees, with feeling
of stiffness.
Nov. 29. Eight drops. Dulness of the head, with transitory at-
tacks of vertigo, frequently recurring in the course of the day.
Nov. 30, Dec. 1. Ten drops in the morning of each day. Violent
pressing over the forehead, from the temples towards the nose, with
feeling of dryness in the latter, after half an hour ; pain in the right
second toe and knees, alternately appearing and disappearing for almost
four hours. The pain in the lower extremities disappeared after drink-
ing beer ; the headache was aggravated.
The headache, and pains in the knees and foot, came on daily at
about 8 A. m., until Dec. 3, and continued until afternoon, when a soft
stool took place. On the 4th they were weaker and not so often, but
he had frequent attacks of vertigo ; he was not perfectly well until the
8th. During the whole time of this proving, he felt very weak and
relaxed, and the sexual impulse was remarkably diminished.
Wur?ri > s Provings (42). 337
41. — Third Proving with the Tincture.
Dec. 8 to 10. Three, four, and six drops, taken in the morning,
produced not the slightest effect.
Dec. 11. Seven drops ; pain and stiffness in the knee manifested
themselves slightly, with much rumbling in the abdomen and frequent
eructations.
Dec. 12. Eight drops produced violent griping in the umbilical
region, troublesome cramp-pain in the knee and calves, ineffectual urg-
ing to stool, and copious urine.
Dec. 13. Wine drops. Drawing and feeling of stiffness alternating
between the right and left knee, frequently recurring (after half an
hour); at the same time, rapidly passing stiffness in the hip-joint ;
griping and rumbling in the bowels the whole forenoon, more painful
when walking than when at rest ; much flatulence, and two, almost
fluid, yellowish stools in the afternoon ; great debility and weariness.
Dec. 14. Ten drops in the morning, caused the pains in the lower
extremities to increase until noon, so as to be frequently troublesome
in walking. Constant pinching in the abdomen around the navel ;
frequent eructations ; inclination to vomit ; frequent urging to urinate,
with scanty emission ; stitches along the urethra. All these symptoms
disappeared in the afternoon.
The drawing pains in both knees, were perceptible for several hours
on the three following days.
During the succeeding week, the prover took occasional doses of
five drops, at two days interval, and perceived slight intimations of
drawing and stiffness in the knees, soon disappearing, especially on
walking ; feeling of looseness in the bowels, and somewhat increased
discharge of urine.
Since this last proving, our colleague, to his own great astonishment,
finds himself perfectly relieved of all the pains which formerly annoyed
him so frequently, and has continued for the past year stronger and more
healthy than ever before.
42. — Wurrrfs Proving with the Tincture.
Dr. Franz Wurm, set. 36, sanguineous temperament, athletic build,
perfectly healthy for years past, one of our most assiduous and careful
provers, made three experiments with colocynth ; the first, with the
strong tincture, of which he took the enormous quantity of six hundred
and forty-one drops in the course of five weeks ; the second, with the
first trituration of the marc ; and the third, with the first dilution of
the tincture.
1842, Nov. 8, 9, 10. One, two, and four drops of the mother tinc-
ture were taken, with no result except that, on the next day,
Nov. 11, his usual stool was absent; six drops at 10 a.m., were
followed by dulness of the head, most severe after dinner, nearly disap-
pearing towards evening ; feeling in the afternoon as if he should have
338 Colocynthis.
a stool ; frequently recurring tearing in the right metatarsus, towards
the great toe joint, in the evening; frequent urination.
Nov. 12. Eight drops half an hour after his accustomed stool.
Another stool at 4 p. m., with slight subsequent burning at the anus.
Nov. 19, 20. Ten and fifteen drops produced no other effect than
a quantity of inodorous flatulence.
Nov. 22. Twenty-five drops. Violent urging to evacuate the
bowels (after five hours), demanding instant attention. Copious fecal
diarrhoea, accompanied by great discharge of wind.
Nov. 23. Thirty drops in the morning. Little appetite at dinner,
although the food tasted well ; insipid taste in the mouth after dinner
for an hour and a half; pretty violent pressing pain in the left little
finger about 6 p. m., particularly towards the middle joint, soon disap-
pearing ; then the same pain in all the right toe-joints, except those of
the great toe, lasting eight minutes.
Nov. 24. Forty drops in the morning. Movements in the bowels,
soon after dinner, followed by an abundant soft stool, succeeded by
griping in the abdomen, particularly in the vesical region ; a thin diar-
rhceic stool at 4 p. m., whereupon the colic remitted.
Nov. 25, 26. Twenty and thirty drops produced almost a repetition
of the same scene, except that the colic was more violent, and lasted
longer.
Nov. 27. Forty drops in the forenoon. He continued perfectly
well, and had no evacuation all day ; slept badly the following night,
was often aroused by vivid dreams, and every time found himself in a
perspiration.
Nov. 28. Fifty drops at 9£ A. m. Pressing in the posterior joint of
the left great toe, as if the boot were too tight, only perceived when
quietly seated, disappearing when walking about ; throbbing in the
same spot, likewise vanishing on motion ; heaviness of the feet, most
troublesome tn the forenoon, as though he had made a great journey
on foot ; constant sensation in both feet when sitting, especially in the
left, as if they were going to sleep. Itching, inducing scratching in
various places, most frequently on the scalp. Movements in the hypo-
gastrium after dinner, disappearing after a soft evacuation.
Nov. 29. Heaviness in the feet, early, after waking, diminishing
after getting up, and going off on going about. A hard, unsatisfactory
evacuation at about 5 p.m., discharged with difficulty. Many and vivid
dreams during the succeeding night ; he woke almost every half-hour.
At the same time, another unpleasant symptom was discovered ; the
prepuce was drawn back, and, as it were, slightly constricted behind
the glans. Every time he brought it forwards, he found it again
drawn back at his next waking.
Nov. 30. Forty drops at 8-^ a.m., and twenty drops at 5 p.m.
Aching in the hypogastrium soon after dinner, ameliorated by the
discharge of abundant fetid flatulence, and disappearing after the sub-
sequent stool, at about 4 p.m. Sensation of violent pressure in the left
temple, continuing the whole afternoon (migraine ?), better while seated,
WimnSs Provings (42). 339
worse when standing and walking, but especially when urinating.
Night's rest interrupted by vivid dreams and frequent waking, when
he always found himself upon his back.
Dec. 1, 2. No medicine. Frequently repeated aching in an upper
hollow tooth ; drawing in the right ancle towards the internal side ;
rapidly passing sensation of pressure in different parts of the body,
especially in the posterior joint of the right middle finger and right
great toe ; an unsatisfactory stool.
Dec. 3. Fifty drops in the forenoon ; after six hours, griping, four
fingers below the navel ; discharge of abundant flatus. Colic very
violent in paroxysms, obliging him to bend forwards. It continued
two hours, and only ceased after the evacuation of a soft stool. He
felt very weak and debilitated in the evening before going to sleep.
Dec. 4. The same feeling of weariness and lassitude on waking the
next morning, but it soon disappeared on moving about ; no evacuation
the whole day ; frequent urination ; itching in various spots on the
body; feeling of pressure in the joints.
Dec. 5. Sixty drops at 8£ a.m. Dulness of the head, most per-
ceptible in the right frontal region, continuing the whole day. Violent
griping pains in the abdomen at 2^- p.m., worst at about three fingers
below the navel, obliging him to bend over, and disappearing after a
pappy stool at 5 p.m. Sensation as if the left foot would go to sleep,
in the evening when sitting. The lassitude, the itching in various
spots, and the feeling of pressure in the joints, as yesterday.
Dec. 6. With the exception of drawing in the calf and thigh, and
absence of an evacuation, no symptoms.
Dec. 7, 8, 9. Fifty, forty, and thirty-Jive drops, taken in the fore-
noon, produced almost identical phenomena : dulness of the head, dis-
charge of abundant flatus after dinner, colic, pappy stools, followed by
disappearance of the abdominal troubles, frequent urination, feeling
of pressure and heaviness in the small of the back. On the 9th, in
addition, transitory drawing in various joints of the upper and lower
limbs, especially of the fingers and toes, disappearing instantaneously
on motion, and as rapidly recurring in rest.
Dec. 1 0, 1 1 . This last symptom troubled him also quite often the two
following days, on which he took no medicine.
Dec. 12. Forty drops. Movements in the abdomen at 5 p.m.,
followed by a soft stool.
Dec. 13. On getting out of bed, drawing in the left popliteal region,
as if the tendons were too short; dulness of the head; fluent coryza;
pressive drawing in the joints of the toes and fingers, as well as in the
right knee-joint. The joint difficulties continued the whole day, but
did not remain long in one place.
Dec. 14. Forty- five drops in the forenoon. Urging to stool, and a
soft evacuation after dinner ; continuance of the coryza ; oppression of
the chest in the evening ; feeling of rawness in the throat, and cough ;
frequent urination.
c. 15. Flying drawing in the posterior joint of the left thumb
340 Colocynthis.
and right great toe, in the right knee, and on the left side of the neck,
especially when turning the head ; coryza less ; roughness in throat,
and oppression of the chest, the same.
The pains in the joints returned for several days, but less frequently
and less violent. On the 17th, in the evening, lie had besides, for
several hours, violent pressure in the small of the back, and the left
foot felt as if it were going to sleep. On the 18th, in the evening,
sprained feeling in all the toes of the left foot when going up stairs.
43. Warm's Proving with the First {centesimal) Trituration.
Dec' 19. Twelve grains taken at noon. Pressing in several of the
finger and toe joints, especially during rest.*
Dec. 20, 21. Twenty-four and forty grains. No symptoms, except
that on the 2 2d he perceived burning in the orifice of the urethra after
urinating, lasting an hour.
Dec. 22, 23. Fifty grains, taken in the forenoon of the first day
and morning of the second, produced no other effect than dulness of
the head, unsatisfactory stool, with burning and sticking in the anus,
and burning in the urethra after urinating.
44. — Wurm's Proving with the First (5 to 100) Trituration.
Dec. 24. Twenty grains, at 9 a. m., produced several unmistakable
Colocynth-symptoms. Cramp on the middle of the left thigh (after
three hours) ; discharge of fetid flatus after dinner, and movements in
the hypogastrium, both symptoms disappearing after an evacuation.
Pressing in some of the toes, and in the calves in the afternoon. To-
wards 5 p.m., universal lassitude, with chills, violent thirst and accelera-
ted pulse ; this febrile excitement lasted for about half an hour. It was
very singular that, during its continuance, he could not, without diffi-
culty, get rid of the idea that he was not in his own room, but in ano-
ther. He felt perfectly well in the evening.
Dec. 25. The usual morning stool was absent. The sensations of
pressure, and drawing in the posterior joint of the right great toe and
ancle and knee-joints, as well as in the left hip, returned in short parox-
ysms, especially when walking around. At 7 p.m., when walking,
cramp-like drawing in the inner side of the right thigh throughout its
whole length ; he felt very much debilitated, but only when at rest. On
the next day, he felt perfectly well, except that he had no stool.
Dec. 27, 28. Thirty and forty grains developed a succession of
symptoms, which continued for twelve days. Discharge of much flatus ;
two unsatisfactory stools. Tension and stiffness in the left knee on get-
ting out of bed on the morning of the 28th; pressure in the posterior
joint of the right great toe in the evening.
Dec. 29. Transitory drawing in the left trochanter, followed by drawing
* Apparently a remaining effect of the last 45 drc^s of the tincture. Ed.
Oest. Zeit.
Wurwrts Provings (46). 341
pressing in the left metatarsus, and when this ceased, drawing in the
teeth (forenoon) ; pressure in the middle of the left thigh, drawing in
right elbow-joint, pressure in the posterior joint of the right great toe,
when moving about, lasting all the evening ; with this, cold feeling in
both upper arms, as if after taking cold, returning for several evenings
in succession ; no stool all day.
Dec. 30. A hard, unsatisfactory stool in the morning ; violent itch-
ing on the abdomen in the umbilical region in the evening for half an
hour ; followed by drawing in the inner side of the left thigh as far as
the flank.
Dec. 31. A stool in the morning and another after dinner, hard and
unsatisfactory; pressing on the posterior joint of the right great toe,
lasting nearly all day, most perceptible during rest; drawing in the
external condyle of the right femur, in the elbow, fingers, toes, but es-
pecially in the knees, on motion.
Jan. 1, 2. The drawing and pressure in the joints returned on these
two days, but less violently and less frequently.
Jan. 3. Three small boils appeared on the left side of the neck with
burning pains, and a larger one at the lower angle of the left scapula.
Drawing on the inner side of the left thigh in the evening.
Jan. 4. Drawing in the right knee-joint in the forenoon, and on this
ceasing, drawing in the right thigh. Constant burning pain in the
boils.
Jan. 5, 6. Two pappy stools a day in the forenoon.
Jan. 7. Drawing in the inner side of the left thigh, the whole after-
noon.
Jan. 8. On the next day he was perfectly well.
45. — Warm's Proving with the First (decimal) Trituration.
Jan. 15 to 19. He took fifteen grains on the morning of the 15th,
and thirty grains on the 16th, 18th, and 19th, and satisfactorily proved
the efficacy of such doses; the results, however, are but a few morbid
phenomena. Movements in the abdomen ; discharge of much flatu-
lence ; more frequent urination ; disturbances in relation to the charac-
ter and time of the stools which were either absent, or instead of com-
ing, as normally, in the morning, appeared in the afternoon and were
either too soft (diarrhceic), or too hard and unsatisfactory.
46. — WurnCs Proving with the First dilution of the Tincture.
Jan. 21 and 24. Ten drops every morning produced no effect,
except that he was waked on the 23d at about 4 a.m., by a violent
pressing-throbbing headache in the forehead. Although the pain went
off on sitting up and moving his head, still his head was very dull all
the forenoon.
342 Colocynthis.
47. — Watzke's Proving with the Tincture.
1842, Nov. 3. I began my experiments with Colocynth when con-
valescing from an isthmitis, with a single drop of the tincture taken in
a spoonful of water at 8 a.m., after a breakfast of bread and milk. With
the exception of slight sensation of nausea towards noon, I perceived
nothing ; it seemed to have no effect upon the still remaining soreness
of the throat. During the succeeding night, excellent refreshing sleep,
with pleasant dreams.
Nov. 4. Four drops on a piece of sugar, at 7, a.m. The head
seemed a little affected soon after the dose. Towards 9 a.m., much
rumbling in the abdomen ; at noon, the same intimations of nausea as
yesterday ; restless at night, and had horrible, exciting dreams.
Nov. 5. Seven drops in a few spoonfuls of water, at 7 a.m. To-
wards 10 a.m., sensation of inflation in the umbilical region, with
compression in the throat and nausea. These symptoms lasted the
whole day, and became worse some hours after dinner. Towards even-
ing, disgust before eating, and inclination to vomit.
Nov. 6. No medicine and no symptoms, except occasional slight
drawings in the shoulder-blades.
Nov. 7. Fifteen drops in a little water, at 8 a. m. This was follow-
ed by frequent eructations of breakfast. Towards noon, movements in
the abdomen, and two brown, thin, almost watery, painless stools, one
following the other in rapid succession. No other symptoms.
Nov. 8 to 11. No medicine; constant sensitiveness of the abdomen
in the umbilical region ; frequently repeated long stitches in the left
chest and left knee ; several pappy stools a day.
Nov. 12. Twenty drops in the morning, soon after breakfast. In
the forenoon, acute pain in the umbilical region, increased by walking ;
subsequently, transitory drawing in the right shoulder ; towards even-
ing, stitches in the left side, cutting short the breathing ; drawing in
the scalp ; painful pressure in the eye-balls, especially when bending
over; frequently returning stitches in the right elbow and fore-arm.
During the whole day, borborygmi and empty eructations.
Nov. 14. Ninety-five drops in half a glass of water, early in the
morning, fasting. The disagreeable, bitter taste of the drug remained
for several minutes in the mouth. Half an hour afterwards, (immedi-
ately after breakfast,) rising of a bitter, white, frothy liquid ; Violent
pain in the umbilical region the whole forenoon, without intermission ;
it was situated in a spot about the size of the hand, and was a bruised
pain, aggravated by walking but not by pressure, and becoming more
tolerable after eructations of air. At times, tivitching stitches from
the umbilical region towards the loins and spine ; intimations of nau-
sea; urging to stool (which, however, was under control). Towards 11
o'clock, constant burning pain in a spot on the right side of the chest;
feeling of roughness in the throat ; pressure in both temples ; smarting
in the eyes ; painfulness of the eye-ball ; excited, irritable state of tem-
per ; taciturnity.
WatzJce's Provings (47). 343
The pain in the abdomen became worse after dinner, gnawing and
boring, and obliged me to sit down or lie and bend forwards ; violent
tenesmus came on at first, with pappy, copious, strong-smelling stools,
ivhich, an hour later, were watery, scanty, yellow, and almost inodor-
ous. Twitching pains in the dorsum of both feet towards the tibia,
when walking in the street. The colic diminished somewhat after tak-
ing black coffee, at 4 p.m., but became much more painful again after
supper,* accompanied by dulness of the head and aching in the sinci-
put, aggravated by bending forwards. Restless sleep at night, vivid
dreams, frequent waking, apparently produced by the continual painful-
ness of the umbilical region.
Nov. 15. No medicine. In the forenoon, occasional sticking pains
in the right chest ; two pappy, yellow, painless stools. In the evening,
painfulness of the whole head and eyes, very much aggravated by bend-
ing forwards ; cons tan t colic, with urging to stool, which was, however,
subject to control. Night very restless ; umbilical region unintermit-
tingly painful ; profuse perspiration towards morning.
Nov. 16. Colic again more violent, gnawing after moving about, in
the forenoon ; somewhat diminished towards noon, but not entirely in-
termitting during the remainder of the day. Frequent pressure and
oppression of the chest in the afternoon ; dull stitches in the chest and
sides. Sensitiveness of the head during the whole day, as though it
were compressed, especially in the sinciput and temples, with painful-
ness of the eye-balls, aggravated by bending forwards ; better in the
open air.
Nov. 17. After a quiet night, I was waked in the morning by grip-
ing in the bowels, and tenesmus, notwithstanding which, the stool that
followed was perfectly normal. The griping disappeared after drinking
black coffee, but returned in the course of the forenoon, accompanied by
rumbling and movements in the abdomen; the sensitiveness of the head
of yesterday, the pressing in the temples, and the painfulness of the eye-
balls, came on again. Bruised pain in the right middle finger, at noon ;
after dinner, a yellow, diarrhceic stool, without tenesmus or pain. In
the evening, painfulness of the umbilical region, stitches in the back ;
spots on the anterior part of the thorax, that were sore and painful, as
if bruised.
The following is a condensed statement of the results of the next ten
days, until the 28th Nov. : " I am not yet free from the effects of the
drug taken during my last proving of the 14th. I am constantly an-
noyed by a feeling of compression, of a hank in the umbilical region,
sometimes more, sometimes less. At times, especially towards morning,
it increases to a piercing or cutting pain. I generally wake in the
morning with colic and tenesmus, and have every day several thin pap-
py stools. I have frequent attacks of the painfulness and aching in the
sinciput and eye-balls, and the dull stitches in the flank, interrupting
* Unquestionably because the anodyne effect of the coffee had continued
until then. — Ed. Oest. Zeit.
344: Colocynthis.
the respiration. Since the 24th, I have perspired very profusely over the
whole body, every night toivards morning, and my wine presents a
very striking similarity in appearance to that in dropsy after scarla-
tina. It is of a faint flesh-color, deposits a light-brown, flocky, une-
qual, translucent sediment, and upon the vessel, small, hard, and solid
reddish crystals, which adhere so strongly that they are not easily re-
moved by water. The urine, passed during the day is somewhat lighter
colored than that made towards evening, night and morning.
" The umbilical pains were much alleviated, and the head difficulties
entirely disappeared, on the appearance of the night-sweats and flesh-
colored urine. These are, then, unquestionable phenomena, on the oc-
currence of which, my medicinal disease, already become chronic, and
resembling a congestion (hyperemia, inflammation) of the small intes-
tines more than anything, was happily brought to an end. Thus we
have a drug-crisis, or lusis !"
Dec. 1. " The above described urine was present also on the 29th
and 30th of November. To-day, the water is bright again, but of a
somewhat deep wine-yellow, and contains a transparent cloud. Every
abdominal symptom has disappeared."
Dec. 4. " The morning sweats, and cloudy reddish urine, with brown,
flocky, mucous sediment, have returned for two days past; the pressing,
sometimes gnawing pains in the umbilical region come on, particularly
in the morning, fasting ; movements and rumbling in the bowels are
often observed. On the evening of the 3d, I had a gnawing, pressing
pain in the inner ball of the left foot, and, subsequently, painful stitches
in the cardiac region on going to bed."
Dec. 10. " Since the 5th, several little boils have been developing
themselves on the ulnar side of both hands, and a stye on the left eye,
which followed the usual course to suppuration — perhaps accidental
phenomena, though I have not been previously troubled with such
symptoms. All the abnormal manifestations have now disappeared,
excepting a tension, a feeling of pressure in the region of the navel."
While I thought that the effects of the drug had long since vanished,
I was taken by surprise on the 18th, at 7 a.m., while writing, with
exceedingly painful long stitches in the right metacarpus, frequently
repeated in the course of a few minutes, and somewhat embarrassing
the operation of opening the hand and stretching the fingers. The
stitches came both during rest and motion; a symptom which I had
never had before. At 8 p.m., while reading, the same symptoms re-
curred, only the pain was more continuous, the stitches more intense and
longer. The same symptoms were repeatedly perceived at different
times on the following days.
After I had no longer for several days observed the slightest trace of
the drug-action, and the process, after a duration of five weeks, was
unquestionably at an end, I undertook a new experiment with the
triturated pulp.
Watzke's Provings (50). 345
48. — Watzke's Proving with the Third (decimal) Trituration.
Dec. 26, 28. Ten (/rains of the third {decimal) trituration were
taken fasting on the morning of each day. The transitory sticking,
drawing, twitching, itching, burning, and smarting, which I subse-
quently observed in different parts of the body, now here and now there,
do not seem to me to stand in the relation of cause and effect with the
drug taken.*
49. — Watzke's Proving with the First (decimal) Trituration.
1843, Jan. 10. Ten grains of the first trituration were followed
by intense bitter taste in the month for some minutes ; three hours later,
griping in the abdomen, especially about the navel, with easily repressed
tenesmus (continuing nearly two hours); a diarrhoeic stool after dinner,
without colic or tenesmus ; during the next days, especially in the fore-
noon, frequent intimations of abdominal pains, weakness, nausea rising
from the stomach ; also irritable disposition, and a strongly-marked
aversion to the drug.
Jan. 14. One grain, taken at 8 a.m., produced merely transitory
griping in the bowels. Having taken two grains, four hours afterwards,
I had painful griping and movements in the gastric region (continuing
for a long while), followed by a soft, almost diarrhoeic stool. Towards
evening, pressive pain in several places on the thorax, in the hepatic
region, and over the heart, impeding respiration (continuing for several
hours.)
Jan. 15. Long stitches on the inner side of the left thio-h, from the
ischiatic tuberosity towards the knee, in the forenoon, when walking (fre-
quently repeated for several minutes) ; towards noon, griping about the
umbilicus, and sensitiveness of the abdominal integuments, aggravated
by external pressure.
50. — Watzke's Proving with the Tincture applied Externally.
The experiments which I instituted in December, 1843, by rubbing
in the tincture on the abdomen, did not, unfortunately, lead to the de-
velopment of a medicinal disease, as I was in hopes they would.
Ten, twenty, thirty, and forty drops produced very slight symptoms
of Colocynth-action, such as transitory griping colic ; several small
soft evacuations a day, with frequent inclination to stool ; clucking in
the inner side of the groin.
* On the other band, tengrains of the same trituration, taken subsequently,
on the morning of Jan. 22, produced unmistakable Colocynth-symptoms.
Movements in the abdomen, frequently repeated during the day; on the fol-
lowing morning, constant, violent smarting on the middle of the tongue at the
apex, as though the part were sore (See Gerstel's Proving, ante, p. 321); draw-
ing, sticking pain on the external side of the thigh, when waking.
Can it be that the deep-seated action of the 95 drops of the tincture, taken five
weeks previously, was too recent, and that the organism was too deeply
affected by it, to respond to the impression of a dose, relatively so weak as a
few grains of the third attenuation? — Watzke.
346 Colocynthis.
Fifty drops, rubbed in towards midnight, produced an unusually
noisy discharge of much flatus in the morning, movements in the bow-
els, sensitiveness of the abdominal integuments, repeated inclination to
stool, which, however, was easily resisted.
One hundred drops caused sensibility around the anus, with freqent
urging to stool, which was unsatisfactory and diarrkasic, but painless ;
clucking in a spot below the navel ; painfulness of the abdominal
integuments (particularly when walking) ; griping in the abdomen and
frequent urination, with an apparently increased flow.
The same symptoms returned with more intensity and annoyance on
repeating the same application the next day. The tenesmus, hardly
indulged before it again returned, became also ineffectual, or produced
only a slight diarrhoeic discharge. On the evening of the same day,
painfulness of the whole head, most troublesome in the frontal region,
aggravated by bowing or turning the head, with incapacity for intellec-
tual exertion — a symptom which I had experienced six months before,
during my proving of Colocynthin hereafter referred to. It then
troubled me for a long time, and, although it now disappeared after a
few hours' continuance, still the violence with wh"ch it attacked me
frightened me from further prosecuting my experiments with the exter-
nal application of the tincture.
I am forty years old, of a sanguineous-bilious temperament, small in
stature, and of a strong constitution, with no special predisposition to
any disease. I have never been seriously unwell, with the exception
of the usual exanthemata during childhood, and some acute congestive
attacks of the head and throat during subsequent years.
Experiments with Colocynthin.
Description. — Colocynthin is a brown or pale-yellow, translucent,
uncrystallizable, brittle substance, with a conchoidal fracture. Its taste
is extraordinarily bitter ; it leaves, after burning, a black, very volu-
minous charcoal ; it is soluble in water, alcohol, and ether.* Chlorine
precipitates the watery solution ; acids and deliquescent salts produce
a greasy precipitate, insoluble in water. The solution of Colocynthin is
precipitated also by tincture of galls, proto-sulphate of iron, and sulphate
of copper, but not by corrosive sublimate, rritrate of silver, or acetate of
lead. The caustic alkalies do not cause a precipitate ; it is not easily
destroyed by nitric acid, as it decomposes it.
The most simple mode of preparing it, according to Vauquelin, is
to exhaust the pulp, freed from the kernel, by water, and evaporate the
solution, when the Colocynthin separates in oily drops, which become
solid on cooling. Braconnot recommends exhausting the watery
extract with alcohol, evaporating the filtrate, and treating with a little
)
* According to Pfaff, (Syst. Mat. Med. III., 170,) sulphuric ether takes up
nothing. — Watzke.
GersteVs Proving s of Colocynthin (52). 347
water, when the Colocynthin remains behind.* We have used both
preparations in our experiments, and detected no difference in their
effects.
According to Pfaff (loc. cit.), Colocynthin stands nearly related, in
its chemical properties, to bryonin. Others are of the opinion that a
further and more exact examination of these two substances would lead
to the conclusion that they were modifications of one and the same
base — a theory, by the by, which, notwithstanding the botanical and
pharmacodynamic affinities of Bryonia and Colocynth, deserves to be
ranked among the dreams of the alchymists, as a pure impossibility.
Our object in proving the Colocynthin was to ascertain -whether the
medicinal power of Colocynth was solely due to its presence (as Pfaff
declares), whether Colocynth and Colocynthin were identical in their
effects upon the human organism, or whether the latter stood in a
similar pathogenetic relation to Colocynth that Quinine does to China.
How far we have accomplished our purpose, our colleagues can judge
from the results of both provings herewith submitted to them.
Besides myself, Colocynthin was tried by Dr. Gerstel upon himself,
and by Dr. Frohlich upon two rabbits. These latter experiments will
be found in the next chapter.
51. — Gerstel' } s proving of Colocynthin, Sixth [decimal) Dilution.
1843, May 28. Dr. Gerstel began with twenty drops of the sixth
decimal dilution (prepared with distilled water), taken fasting at V a.m.
He perceived nothing abnormal, except a slight intimation of dulness
of the head, and a gentle feeling of warmth in the abdomen, as if from
a congestion of the bowels (!) followed by a copious discharge of flatus
in the afternoon.
May 29. Thirty drops on this day, and twenty drops on June 3,
produced no striking phenomena.
52. — GersteVs Proving of Colocynthin, Fifth {decimal) Dilution.
June 4. Forty drops taken in the morning, fasting. Soon after the
dose, slight dulness in the sinciput ; formication of the eyelids, and
crawling in the lower incisors on the left side ; pressure in the temple ;
prickling and metallic taste on the point of the tongue. These symp-
toms soon disappeared, and there were no others during the day.
During the night of the -sixth, he had a pollution — a very unusual
occurrence with him.
June 6. Fifty drops in the morning, fasting. Four painless, pappy
stools during the day ; sensations of tenesmus in the urethra and rectum
after urinating^
June 7. Fifty drops in the morning, fasting. Soon after the dose,
pain in a hollow molar, and drawing in the incisors, with sensation of
* Handw. d. Chem. von Liebig, Poggendorf und Wohler, Art. Kolocynthin,
and Pfaff, loc. cit. — Watzke.
348 Colocynthis.
swelling of the left cheek ; tickling in the left external ear, with burn-
ing of the tip ; dulness in the left side of the head, especially in the
temporal region ; painfulness of the whole left side of the face ; para-
lytic weakness of the right fore-arm while writing ; tearing in the left
shoulder ; prickling in the left calf and sole ; tickling in the rectum ;
crawling in the penis, with sexual desire. In the course of the fore-
noon, weakness of the legs, transitory heartburn, and feeling of moisture
at the anus.
June 8. Fifty drops produced not the slightest effect, (a fact which
throws considerable doubt upon the numerous phenomena observed the
preceding day. Is it not possible that such almost purely subjective
alterations of sensation might be, for the most part, the effect of the
prover's imagination, or of his overstrained attention to his own feelings ?
Ed. Oest. Zeit.)
53. — GersteVs proving of Colocynthin, Fourth (decimal) Dilution.
June 20. Thirty drops of the fourth dilution produced no symp-
toms.
June 21. Sixty drops, with no better result.
June 22. One hundred drops, taken in the morning, gave rise to
clear manifestations of Colocynth. Intimations of colic, with inflation
in the umbilical region ; pressing pain in both soles, with feeling as if
they were swollen*; frequent urination. The same dose repeated in
the evening before going to bed, manifested itself in an unmistakable
manner, by slight colic some fingers below the navel (after six hours)
and palpitation, but particularly by pulsation in the scrobiculus, accom-
panied by prickling stitches on the back, in the neighborhood of the
middle thoracic vertebrae.
54. — GersteVs Proving of Colocynthin, Third (decimal) Dilution.
June 24. Fifty drops of the third dilution'm the morning, fasting,
left behind a persistent, earthy, bitter taste upon the tongue, and a de-
cided feeling of heat in the stomach, as if from hot water. Eighty
drops, taken in the evening of the same day, produced the same earthy,
bitter taste ; sharp inpressing pain in some spots on the nape, as if
from a sprain, aggravated by movement, the spot itself being sensitive
to pressure from without ; at the same time, short hacking cough, excited
by a tickling in the throat ; vivid dreams at night ; continual burning
pressure in the stomach up into the oesophagus during the following
forenoon.
55. — GersteVs Proving of Colocynthin, Second (decimal) Dilution.
June 27. Twenty drops of the second dilution taken in the morning,
fasting. Soon after the dose, seizure of the whole head ; slight pains
here and there in the left leg and arm ; congestion towards the genital
* Compare Weinke's proving, ante, p. 334.
Watzke's Provings of Colocynthin. 349
organs, especially the scrotum, with feeling of heat and persistent burn-
ing in a small spot upon the same, without erections; stitches in the
region of the lowest dorsal vertebrae ; pain in the right great toe, ac-
companied by a dull, not easily described feeling, as of heat on various
places on the right thigh, especially on the posterior side in the course
of the sciatic nerve ; at the same time, a similar sensation in the external
ball of the little toe of the same side. Some hours later, pressure in
the left cheek-bone and left great toe ; burning in the posterior wall of
the pharynx ; colic pains, with inflation of the abdomen. All these
symptoms were developed when seated, lasted for almost two hours, and
disappeared entirely on walking.
June 28. Forty drops of tJie second dilution were taken, but the
prover remarks that, taking a long and fatiguing walk immediately
after the medicine, he did not pay the requisite attention to the symp-
toms that might have been caused by the dose.*
June 29. " Sixty drops of the second dilution, taken early, fasting,
upon sugar of milk, caused a persistent, disgusting, bitter taste in the
mouth ; soon after, burning sticking, and sensation of warmth on the
dorsum of the right foot ; pressing-digging pain in the external side of
the second toe of the left foot ; cramp-pain in the muscles of the left
wrist ; feeling of pressure and swelling in the under eyelids ; slight in-
timations of colic, drawing from the hypogastrium to the hepatic region ;
accompanied by shuddering in the scrotum (?), with erections, and pain
in the buttock.
Watzke's Provings of Colocynthin.
In reference to my slender experiments with Colocynthin, I must
premise that, in the beginning of the year 1843, I had commenced some
trials with massive doses of common salt, and continued them until the
end of April. The obstinate, deep-seated effects of that drug, however,
continued for several weeks after I had taken the last dose. The irre-
gularity of the stools, both in respect to time, repetition, and character,
which I had observed during the whole proving, continued far into May ;
the characteristic painful tension on the flexor side of the joints, espe-
cially of the groins and knee, also frequently returned. My appetite
continued somewhat slight, my sleep was disturbed, and I felt for seve-
ral weeks uncommonly dull, depressed, and debilitated.
Previous to my first experiment with the Colocynthin, I had suffered
for eight or ten days from a peculiar, very troublesome, periodical spasm
of the urethra and rectum. There frequently came on in the afternoon,
but irregularly, sometimes several times in an hour, often at intervals of
five or ten minutes, and again once in two, three, or four hours, sen-
sibility of the urethra, not aggravated by external pressure, a constric-
* We are but little concerned about the loss to our Materia Medica of those
symptoms which are not recorded through the insufficient watchfulness of the
I »rover over his own sensations. Not only should the experimenter be on the
ook out for symptoms, but the symptoms should be such as to compel his at-
tention. — Ed. Oest. Zeit.
350 Colocynthis.
tive pain in that canal, and in the rectum, with tenesmus of both passa-
ges The urine was clear and in sufficient quantity, and discharged
without pain ; with the emission of urine, the rectal tenesmus generals-
disappeared also. This latter could generally be controlled, but drove
me several times a day to stool, which was soft, rather fluid, without
preparatory griping, and not accompanied nor followed by tenesmus.
There was, besides, not the least discharge from the urethra, nor the
slightest disorder in the genital system.
oG. — Watzke's Proving of Colocynthin, Sixth (decimal) Dilution.
1843. May 21, 22, and 23. My friend, Dr. Gerstel, having informed
me that Colocynth had excited in him symptoms similar to those from
which I was suffering, and having suggested that it would, perhaps, be
serviceable in removing the troublesome effects of natrum-muriaticum
which I have above related, I took twice each day six drops of the
sixth [decimal) dilution of Colocynthin. With the exception that, on
the morning of the 22d, I awoke with griping and movements in the
abdomen, 1 noticed no trace t>f Colocynth-symptoms. The urinary
and fsecal troubles were scarce any relieved.
57. — Watzheh Proving of Colocynthin, Fifth {decimal) Dilution.
May 24. — I proceeded, therefore, to the fifth dilution, of which I
took two doses in the forenoon, of six drops each, and on the 25th, of
ten drops each. On both days I had two scanty, fluid stools, with no
tenesmus, and scarce perceptible colic, one at midday and the other in
the evening.
May 26. In the morning, two soft, rapidly and easily discharged
stools in quick succession, which strikingly recalled the evacuations
during my former proving of Colocynth. No other symptoms. My
stool and urine difficulties were not so prominent, and my appetite be-
gan to increase a little.
58. — WalzJce's Proving of Colocynthin, Fourth {decimal) Dilution.
May 26, 28, and 31. At noon of the first day, six drops of the
fourth dilution, and in the morning of the other two days, ten drops
each time. In the afternoon of the 26th, some slight, rapid, brown,
soft stools. In the evening I felt all over hotter than usual, and
remarkably depressed, but nevertheless had an excellent appetite. I
slept very restlessly the following night, had many and vivid dreams,
and perspired profusely towards morning.
May 27. In the morning, great depression, dull headache in the
frontal region, aching in the eye-balls, aggravated by straining the
sight, moving the eyes rapidly, and bowing the head, lasting all day.
Several soft stools, rapidly and easily discharged.
May 28. All these symptoms continued, but much more mildly.
A very striking symptom was a feeling of great stiffness and heaviness
in the tibiae. Towards evening, sticking, continuing for several minutes,
WatzMs Provings of Coloeynthin (60). 351
in the epigastrium, which was tense and inflated. The urethral and
rectal spasm, formerly so troublesome, and which had been somewhat
mitigated for a day or two past, disappeared wholly on the 28th, and
has not shown a trace of itself since.
59. — Watzke's Proving of Coloeynthin, Third {decimal) Dilution.
June 7. For several days after the conclusion of my previous
experiments with Coloeynthin, which were finished on the 31st of
May, I perceived transitory symptoms of Colocynth, such as pinching
and movements in the umbilical region, sticking in the epigastrium,
several soft, easily and rapidly passing stools a day, painfulness in the
frontal region, and aching in the eye-balls. Towards the evening of June
7th, painful tension in the right inguinal region, and drawing along the
spermatic cord into the right testicle, which was somewhat sensitive.
I slept w T ell during the night.
June 8. In the morning, the sensibility of the testicle and the ten-
sion in the inguinal region were worse, and were aggravated by walk-
ing, bending over, and going up stairs. Appetite excellent ; two soft,
brown stools every day. In the evening, frequent urging to urinate.
"No perceptible swelling in the groin ; the right testicle, however, and
particularly the epididymis, was considerably swollen and painful to
external touch.
June 9. After a quiet night, the swelling and sensitiveness of the
testicle and tension in the groin were less, but became worse again
towards noon after long going about, and were still further aggravated
in the evening. Stitches now came on, when walking, from the small
of the back to the groin, and a hard tread caused pain in the right
testicle, so that at last I feared to move about. At the same time, the
left testicle became sensitive also. The pain was much ameliorated by
rest, and especially by bending over.
In order to satisfy myself whether these phenomena were the
remaining results of my salt-proving, as I conjectured them to be, or
were attributable to the Coloeynthin, I took, at 8 p.m. of the 9th, five
drops of the third dilution.
June 10. Five drops of the third dilution, taken in the morning.
The troubles of the groin and testicle were already less perceptible, and
on the next day (11th) had wholly disappeared, and did not return on
this or following days, even after a great deal of exercise.
June 15, 16. Ten drops of the third dilution on the first day, and
sixteen drops on the second. No symptoms, except slight pinching
colic, and transitory, easily controlled, urging to stool.
60. — Watzke's Proving of Coloeynthin, Second (decimal) Dilution.
June 18. Ten drops of the second dilution, on sugar, at 9 a.m. On
going out after it, it appeared to me as though my vision were sharper
than usual. Looking through my ordinary spectacles was rather strain-
z
352 Colocynthis.
ing ; slight dulness of the head, sensibility in the temples and forehead,,
transitory attack of vertigo.
Three hours later, after violent pinching in the umbilical region, and
strong, irresistible inclination to stool, a scanty brownish-red evacuation
with painful tenesmus, lasting some ten minutes. Inclination to stool
several times in the afternoon ; fine stitches in the scrobiculus, and pinch-
ing in the bowels. Towards evening, unusual debility and depression,
heat in the whole body, thirst, somewhat accelerated pulse; towards 11
p.m., a copious, thin, pappy evacuation, easily and rapidly discharged
without tenesmus. Very restless sleep at night ; at first, dry heat and
tossing about ; later, toward morning, sweat. In the morning, depres-
sion and weariness of the whole body, painful pressure in the eyeballs
and temples, appetite somewhat less, pulse still over 90.
June 19. No medicine; great depression all day; heat, accelerated
pulse ; dull head- and eye-ache, increased thirst, no stool ; urine clear ;
in the afternoon, and especially in the evening, aggravation of the
symptoms ; (I could hardly keep myself on my legs). In bed, painful-
ness and feeling of heat along the whole spine ; chest somewhat painful
and oppressed ; at times, dry cough ; frequently repeated stitches from
the left axilla down to the elbow ; pulse 100 ; sleep excessively restless;
at first, dry heat, then some perspiration ; uninterrupted, confused
dreams.
June 20. In the morning, dulness of the head, painful n ess of the
eyeballs, debility — but in less degree than yesterday ; great desire to lie
down, requiring great exertion to get off the bed ; increased tempera-
ture of the skin; pulse 92. The feeling of depression and debility in-
creased towards noon ; accompanied by painfulness of the whole head,
especially of the temporal and frontal regions, scalp and eyeballs, ag-
gravated by moving the eyes, straining the sight, or bending forwards ;
at times, stitches in the brain. There was a return also of the feeling
of warmth and sensitiveness along the spine, the oppression of the chest,
and dry cough. At the same time, feeling of roughness in the throat,
repeated stitches in the scrobiculus, painfulness of the malleoli. No
pain in swallowing, nor difficulty in taking a long inspiration ; appetite
somewhat less ; much thirst ; tongue moist, slightly coated ; taste natu-
ral ; no stool all day ; urine fiery, becomes cloudy on standing, but de-
posits no sediment. Amelioration of all the symptoms in rest. Night
good ; I awoke several times and always found myself in a profuse per-
spiration.
June 21. On getting up at 4£ a.m., I felt myself much strengthened
by sleep and the head scarce affected at all. Breakfast, cold bread and
milk, relished highly. Urine less highly colored than yesterday, and
taking a longer time to become cloudy. Stool soon after breakfast,
formed and normal; an hour afterwards, a second diarrhceic evacuation.
I felt very comfortable until towards noon ; head somewhat heavy, but
not painful ; the cough, which was still occasionally excited by the rough-
ness in the throat, caused no pain either in the chest or abdomen, and
was accompanied by a whitish-yellow mucus, expectorated without diffi-
Watzlce's Provings of Colocynthin. 353
culty. From half-past 11 a.m., I rode for an hour in the rail-cars, and
while riding felt the pain in my head becoming more perceptible. The
concussions of the cars became by degrees more painful, and on coming
out, I was obliged to move slowly and to tread softly, as the contrary
course seemed to make the brain shake about, as if loose, against the
scull (in the^ median vertical region) ; this was accompanied by very se-
vere sore pain, and as it lasted during the whole quarter of an hour's walk,
put me in a very bad humor. The cough, which came on occasionally,
produced violent stitches through the cerebellum. I perceived no de-
cided pain in the spine, but noticed the former sensation of pressure and
warmth.
Rest and dinner, meal-porridge, fricassed chicken and water, (eaten
with much relish,) so far set aside these symptoms that I took my seat
in the cars again with renewed good humor. But they returned
during the ride, and still more on leaving the cars, in all their former
severity. In addition, I was troubled the whole afternoon with a dis-
agreeable feeling of chilliness, great debility, unusual want of temper, so
that I could not bring myself to take notice of the stitches, tearings,
pressings, crampings, and such little matters, which appeared and disap-
peared in various parts of the body, especially in the joints and external
side of the thighs and upper arms ; (what struck me most was a cramp
pain in the penis which lasted several minutes, during which it seemed
as if it were bent double). A cup of black coffee immediately relieved
the symptoms, but they did not entirely disappear until I went to bed,
which I was glad to do at 1 p.m. I slept uneasily, and perspired co-
piously, but felt pretty well when I awoke the next morning.
June 22. I coughed frequently during the early part of the morn-
ing, and raised without difficulty a thick, yellow mucus, but had no
pain either in the throat, chest, or head. I was able to resume my
usual morning ablution of the whole body with cold water with toler-
able ease, though previous to yesterday I had omitted it altogether,
and had only done it then with great repugnance and no great
thoroughness. The morning urine was somewhat more highly colored,
but deposited no sediment.
Notwithstanding I rode and walked much, the amelioration con-
tinued until towards 6 p.m. Heaviness and pain in the occiput and
painfulness of the eyeballs then came on; on coughing occasionally, I
perceived the previous exceedingly painful stitches darting through the
cerebellum like lightning ; a heavy tread also caused stitches to traverse
the occiput. In addition, the chilliness, debility, and want of temper
of yesterday appeared again, and, with the headache and pains in the
eyes, continued to increase until 8 p.m., when I went to bed. There
I began gradually to grow better, but I did not feel able to get up
until after a cup of black coffee, which I took at about 9 o'clock, when
I read and wrote a little. Profuse perspiration during the night.
June 24, 25, 26. A good deal of perspiration nights ; felt well in
the mornings ; loose cough; excellent appetite for dinner; occasional
354 Colocynthis.
pressure on the vertex in the evening ; sensitiveness of the cerebellum
(on rapidly turning the head).
June 29. Perfectly well, with the exception of an occasional cough,
accompanied by scanty, easily raised expectoration.*
CHAPTEE IX.
Experiments on Animals.
Provings upon the various races of domestic animals are the sine 1
qua non of a rational homoeopathic practice for the veterinary physician ;
they must constitute the foundation of their Materia Medica. They
are of value for us, too, inasfar as they exhibit (per analogiam) the
pathological changes which a fully developed drug sickness is capable
of producing in the human body. They are the only source of such
information to us in thoss cases in which accidental poisonings and the
subsequent post-mortem examination have not revealed to us the actual
changes which take place in man's organism.
The experiments which we have made upon animals with Colocynth
have remained far behind our desires. We had flattered ourselves with
the expectation of enlarging and perfecting our Materia Medica on
the veterinary side also, by means of a satisfactory course of provings
upon animals. But we found the plan attended by greater difficulties
than we had imagined. Half of these arise from the position in which
physicians in full practice are placed, and cannot be avoided; and could
we expect by future provings to remove the other half, we could not
but still perceive that the object could not as well be attained as by
veterinary practitioners themselves.
So far as Colocynth is concerned, we have fortunately the necessary
pathological information in the examinations which have been made of
those who have died from poisonous doses (see ante, Chap. IV.) The
veterinary physician, too, is spared much toilsome labor by the experi-
ments of Viborg and Orfila, which, together with those of our col-
league, Dr. Frohlich, we proceed to relate.
* I would willingly join those who have never proved a drug upon their
own bodies, and recognize in the above train of symptoms nothing more than
an accidental acute bronchial catarrh. But, apart from the considerations
that I am not in the least degree inclined to catarrh, having not been so
affected for years, and that I cannot assign any of the usual causes for its
appearance, the abdominal symptoms which accompanied its commencement
presented the greatest possible similarity to those which attended my former
proving of Colocynth. The headaches, however, which continued during the
whole malady, were so violent and so prominent, that I have no hesitation in '
considering the disorder of the brain as the primary trouble, and the slight
affection of the bronchial mucous membrane as merely secondary. — Watzke.
OrfiWs Provmgs (62). 355
61. — Viborg's Proving s upon Animals.
t Viborg experimented (Abhandlungen fur Thierarzte, b. 4) on
different domestic animals.
A watery infusion of 2£ ounces of Colocynth-pulp was administered
to a horse, with no other result than frequent urination, excited appetite,
increased and well-digested stools. Five and a half ounces of the tritu-
rated powder produced the same effect.
Another horse was unaffected by from one to five-and-a-half ounces of
the Colocynth apple. Six ounces produced (after 24 hours) copious
discharge of loose stool with increased appetite ; the pulse, however, was
smaller and slower.
An infusion of two ounces, administered to a ram, caused (in 12
hours) violent diarrhoea, lasting two days ; loss of appetite and debility.
He was better on the third day. Half an ounce produced no effect upon
a sheep ; two ounces produced hard evacuation in another.
Two drams of the marc occasioned increased appetite and slight di-
arrhoea in a swine. Diarrhoea and violent vomiting were brought on in
an old poodle by two drams.
62. — Orjilas 1 Provings upon Dogs.
Orfila [Toxicol., sec. edit., p. 34) instituted six experiments with
Colocynth upon dogs.
1. A small, hungry dog took, at noon, a decoction of two drams of
Colocynth, which was so diluted with water as to be colorless and taste-
less. The oesophagus was tied, he endeavored to vomit, had vertigo
after four hours, and died in the night. (From the Colocynth or the
operation ? Ed. Oest. Zeit.)
2. The oesophagus of a medium-sized dog was tied, after two ounces
of extract had been administered to him. He soon after manifested vio-
lent efforts to vomit ; in four hours his gait became unsteady and he fell.
Two hours subsequently he gave scarce any signs of life, and suffered
himself to be shoved about like a lifeless mass. Death in eleven hours
after the dose.
In the stomach was found a part of the still undissolved extract ; mu-
cous membrane, dark red, with blackish red streaks ; muscular coat,
cherry red ; intestines but little changed, except the rectum, the mucous
lining of which was highly inflamed, and of a vivid red ; lungs filled
with blood, but crepitating ; cerebral vessels turged with black blood ;
pia mater much injected.
3. An infusion of two ounces of Colocynth in wine was introduced
into the stomach of a moderately large dog, and the oesophagus tied.
He whined during the day, became weak, and had two copious stools.
Death in 22 hours.
Mucous membrane of stomach, duodenum and ilium, reddened
throughout its whole extent with dark red spots ; jejunum and coecum,
and commencement of the colon almost normal ; in the lower part of
356 Colocynthis.
the colon, and in the rectum, blackish, elevated streaks were scattered
upon a ground of a vivid red ; lungs healthy.
4. An opening was made at 9 a.m., in the oesophagus of a medium-
sized dog; two drams of finely-powdered Colocynth were inserted and
a ligature applied. At 2 p.m., he had a fluid, blackish evacuation,
whined a great deal, but showed no signs of vertigo or convulsions.
At 8 p.m. he could no longer stand up, but lay like a lifeless mass ;
respiration somewhat accelerated and labored. He lay motionless on
his side until he died at midnight.
The stomach was internally purple, and contained, besides food and
Colocynth, a considerable quantity of fluid. At the bottom the mem-
brane was blackish red, but otherwise of a bright red ; the duodenum,
ilium, ccecum, and a portion of the colon were intensely reddened ; the
rectum showed a number of bright red spots.
5. Two and a half drams of Colocynth were digested for six hours in
five ounces of white wine, and the fluid introduced into the stomach of
a dog at 11 a.m., the oesophagus being then tied. At 6 p.m., the animal
passed two fluid stools, and whined violently ; he died in the night. A
Colocynth apple, which he had been made to swallow the day before,
had been vomited up after being down an hour.
Mucous membrane of the rectum and lower part of the colon dark
red, and the subjacent muscular tissue also inflamed; lungs, stomach,
and other viscera not specially changed.
6. A wound was made in the inner side of the thigh of a dog, two
drams of finely- powdered Colocynth inserted, and the lips brought to-
gether. The animal did not seem troubled on the second day, did not
whine, and went about as usual, but died during the following night.
The mucous membrane of the rectum was very much altered ; almost
the whole surface was covered with blood-red spots; the rest of the di-
gestive canal and the lungs were unaltered ; the wounded leg exhibited
an extensive inflammation with infiltration of blood, but no scab.
63. — FrbhlicJi's Provings upon Rabbits.
Dr. Frohlicii experimented with rabbits, with the tincture, the tri-
turated powder, and with Coloeynthin. His experiments are worthy of
study, as the gradual poisoning permitted a longer and more careful ob-
servation, and they are accompauied by a most conscientious post mor-
tem examination.
1. 1842, Dec. 25. A strong, white rabbit, ten weeks old, received
in the morning ten, at noon fifteen, and in the evening twenty-five drops
of the tincture. Not the slightest alteration in the creature could be
seen, and on the following morning thirty additional drops were ad-
ministered. Nothing was noticed except a little less liveliness in the
animal's movements. Towards evening, when it received two grains of
the finely-powdered pulp, it sat crouched up in a corner ; when dis-
turbed and pushed about, it seemed to move with difficulty. It ate with
relish, nevertheless, during the whole day, the apples which were thrown
FrolilicKs Provings on Rabbits (63). 357
to it, and on the two following days, on which it received no medicine,
though it was constantly dull and moved with great lassitude, it con-
tinually manifested a strikingly g®od appetite.
Dec. 29, 30. It had ten drops of the tincture, morning and evening
of each day. On the 31st, it seemed very sick; was exceedingly
feeble ; could not, for instance, get over a low threshold an inch high,
but remained with the hind legs hanging over it. When pushed for-
wards, it did not use its feet as usual, but bent up, and went on in a
sort of shuffling gallop. Ten drops of the tincture were given on the
same morning, whereupon it became gradually weaker, and died at
about 2 p.m.
Section, twenty hours after death. The animal was emaciated ; skin
easily separated, tender on the hind legs, and coming off in pieces ; the
subcutaneous and deeper areolar tissue on the hind legs infiltrated with
a gelatinous, perfectly transparent mass, so that the course of the ten-
dons and several injected vessels could be distinctly traced. Muscles
pale and flaccid. Nothing abnormal in the fore-paws. Lungs small,
thickened in bands, pale pink on the edges, flesh red in the middle.
Heart pale, relaxed, with the coronary vessels plainly injected ; some
serum in the pericardium. Stomach filled with a grayish, amorphous
substance ; mucous coat pale, with dendritic injection of the vessels,
easily torn ; the mysenteric vessels injected with bright red blood
throughout the whole course of the intestine ; chyme, here and there
in the ilium ; the stomach-like enlargement at the commencement of
the colon, stuffed with amorphous masses of faeces ; in the lower part
of the canal, small, soft, formed faeces scattered about. Liver much
enlarged ; its upper surface, towards the right exterior lobe, marbled
with dark and pale red ; section of that lobe presenting a granulated
appearance throughout, in other places only in spots, the upper surface
decidedly tinged ; the whole five lobes exhibiting cavities of the size of
millet-seeds, filled with a purulent-looking fluid ; gall-bladder distended
with a similar liquid. Kidneys pale. Bladder empty.
2. A brownish gray rabbit, nine weeks old, had taken daily, for eight
days, five grains of the first (decimal) trituration of Colocynth with
sugar of milk, without manifesting any particular symptoms. 1843,
Jan. 13. At 8 a.m., Frohlich gave him, at a single dose, forty drops
of the clear Colocynth tincture. He became weak half an hour after
the dose, and remained motionless in a single spot, with his eyes fixed
and staring. Towards noon, he passed a considerable quantity of loose,
light brown fasces, and afterwards some whitish fluid. He squatted
sadly in one corner the whole afternoon, with hair erect and half-closed
eyes, and died at 7 p.m.
Section, twelve hours after death. Emaciation; veins of the thighs
filled with dark-colored blood; nothing abnormal in the sciatic nerve
or spinal marrow; cerebral vessels injected dark red; brain and lungs
normal ; right cavities of the heart and veins at the base turgid with
venous blood ; left cavities emnty. Stomach marked with a few in-
jected vessels of a bright red, radiating from the upper curve, and filled
358 Colocyntliis.
full with a firm mass of food, which was covered with a layer of mucus,,
especially toward the pyloric extremity; inner mucous coat pale, easily
torn. Upper part of the intestines entirely empty throughout ; com-
mencement of the colon, and its enlargement, adjacent to the ilium, full
of air and a pappy mass of faeces ; further on, until this enlargement
was lost in the coecum, firm, well-formed faeces. Adhesions in places
between the large and small intestines; the whole mass, as well as
the mesentery throughout the entire intestinal tract, was marked with
bright red injected vessels surrounding the bowels. The lower portion
of the intestine marked with a straight vessel, bright red in its upper
part, but dark red towards the end ; inner surface tinged entirely red
only at its extremity. Liver of normal size, color, and consistence,
scantily set with whitish, mullet-seed points, permitting a purulent
moisture to escape on being opened; gall-bladder distended with thin,
brownish bile.
3. A strong rabbit, five months old, had gradually received, in the
course of two months, forty grains of the first trituration of Colocynth-
pulp, and seven hundred drops of the tincture {twenty to fifty drops a
day), without being strikingly affected by it. Having remained four
days without any medicine, it received, April 26, 1843, one, 27th, two,
and 29th, five grains of Colocynthin, dissolved in a little water. No
change was noticed, except a momentary impression and some slug-
gishness. From April 30 to May 4, no medicine was given and no
symptom perceived ; on the contrary, the animal, especially the latter
part of the time, was lively, and had an excellent appetite. On the
5th of May, at 4 p.m., seven grains of Colocynthin were given with a
little water, and the next morning it was found dead.
Section. The animal was not emaciated ; on the contrary, pretty
copious deposits of fat were found beneath the skin and in the inter-
muscular tissue ; brain, normal ; lungs, pale rose color, thickened in
bands ; heart, dusky red ; right cavities and great veins filled with
pitch-black coagulated blood, left cavities filled with blood of the same
color, but thin and fluid. (Esophagus pale red ; stomach distended
with gray aliment ; injected vessels of a dark color on the anterior and
posterior parietes, proceeding from the smaller curvature ; mucous
membrane on the smaller curvature, especially towards and about the
pylorus, flesh red, gradually diminishing in intensity towards the great
curvature, and exhibiting, when examined through a lensj red points
collected in spots; membrane firm. Small intestine full of a yellowish
chyme; mucous lining pale red; mesenteric vessel^ bright red and
injected, embracing the whole extent of the intestine ; colon filled with
fetid, pappy faeces \ mesocolic vessels distended, dark red, especially
remarkable in the great veins accompanying the rectum to its termina-
tion. The mucous lining of the colon not altered ; spleen normal ;
liver presenting a single protuberant, suppurating point ; kidneys,
sciatic nerve, and spinal marrow normal.
4. 1843, July 26. Dr. Frohlich administered to a strong doe-
rabbit, five months old, five grains of Colocynthin in some water ; the
Homoeopathic Cures with Colocynth. 359
dose was repeated the next day, after which the animal became dull,
but continued to eat with appetite. On the 28th and 29th, she re-
ceived seven grains each time, and began to seem very ill on the last
day. On the 30th, she had, during the day, several thin stools ; in
the evening, notwithstanding she still fed, she seemed extremely feeble,
and died during the night.
Section, about ten hours after death. No emaciation ; brain, heart,
and lungs healthy ; liver of normal consistence, but strewed with cysts
from the size of a millet-seed to that of a pea, filled with a serous fluid
and distinguished by snow-white, hardish points, not rising above the
surface, but a little depressed ; the cysts themselves covered with in-
jected bloodvessels. Similar phenomena in the intestines. Stomach
eroded in one place to the external membrane ; the mucous lining red-
dened, easily separated, and thickly set with brownish black points ;
vivid reddening of the mucous lining of the small intestines ; mesente-
ric vessels congested ; uterus dark red at its fundus and containing a
small foetus (like a Proteus anguinus, but without a trace of an eye,)
together with the placenta and membranes.
CHAPTER X.
Homoeopathic Cures with Colocynth.
Coloeynth has achieved its most brilliant therapeutic triumphs in the
province of the Neuroses. Neuralgic and hypersesthesic affections of the
trigeminus, the solar plexus, the lumbar and femoral nerves, and their
ramifications are those which have been chiefly excited, and therefore
cured, by its agency. Such are by far the greater part of the cases re-
corded in our literature, as having been cured by Colocynth, and even
the few hyperajmic and inflammatory difficulties that have disappeared
under its administration, are rather to be considered as having yielded
to the predominant influence of the affection of the nerves.
1. Neuralgic and &i/pera?sthcsic Affections of the Trigeminus.
1. A young woman, 24 years of age, of scrofulous constitution, fair
complexion, and not fully developed growth, became, all at once,
subject to attacks of unusually violent, pressive, tearing headache.
While it lasted, she could not lie down, but stood bent double, and gave
vent to screams and tears. When it subsided she had paroxysms of
suffocation ; the chest felt constricted, she clenched her hands, and
gasped for breath.* She then became composed, spoke, and remained
* The symptoms of the respiration are plainly due to a reflex influence from
the brain, 'and especially from the medulla oblongata, the common origin of the
trigeminus and vagus, upon the peripheric pulmonary branches of the vagus.
If, however, any one should prefer to consider the foregoing case as a spinal
neurosis of the cerebral system, we have no special objection to offer. " The
external headaches, apparently seated in the integuments and galea aponeu-
rotica, which so frequently accompany affections of the cervical portion of the
spine, are easily explained, as the occipital and auricular nerves, distributed
360 Colocynthis.
quiet for half an hour, or even several hours, when the attack would
return. Dr. Schindler, to whom the patient applied, after she had suf-
fered from this affection for 4 weeks, first had recourse to Belladonna,
without any result. A dose of Colocynth (how much ?) having been
administered, the paroxysms became less frequent, but so much the
more intense. It was necessary to recur to its use six times (at what
intervals ?) before the complaint quite gave way. — Thorer's Prac.
Beitrdge, Band ii. 10.)
2. Dr. Schuler gives the following interesting case of cure by Colo-
cynth (Prac. Mitth. der Corresp. Gesellsch. Horn. Aerzte, 1827, s.
39, et seq.) It is one of encephalalgia, complicated with ophthalmia,
the latter having come on after the headache had lasted a long time
with scarcely any intermission. Dr. Schuler found the left eye quite
blind from the previous allopathic treatment, and the other, though still
useful, the seat of burning, cutting pain. The patient also complained
of congestion in the head, and of a copious acrid discharge from both
eyes. Two drops of tincture of Colocynth, every 3 hours, removed
the headache completely within 24 hours, and had a sensible effect in
diminishing the pain in the eye. Under a continuance of the Colocynth,
the sight of the eye was preserved, and the patient completely restored
in eight days.
Our opinion, subject to correction, on this case is, that the headache
arose from cerebral congestion, and was the primary affection ; and that
the ophthalmia was secondary to it, and produced by the sympathetic
affection of the nerves supplying the eye, derived from the trigeminus,
and the twigs of the sympathetic in connection with it. Colocynth
cannot cure a primary ophthalmia, because it cannot give rise to one.
3. A boy, 13 years of age, had complained for four days of violent
stitches in the forehead and eyes, from without inwards. The pain con-
tinued day and night, only diminishing for a few moments to return
with increased seventy. He became feverish, with bitter taste in the
mouth, total loss of appetite, and constipation. Six hours after a dose
of Colocynth 30, the pain had disappeared ; next day the patient
quitted his bed. — (Attomyr's Briefe iibcr Horn. I., 4.) We regard
the complaint as a hyperaesthesia of the supra-orbital and ophthalmic
branches of the fifth.
4. A hemicrania in a woman turned 50, occupying the left side, re-
turning periodically at 5 in the afternoon, and which had lasted several
years, was, after fruitless treatment by allopathic means, somewhat alle-
viated by Asarum, and disappeared entirely and permanently under a few
days' use of Colocynth.— ^(Attomyr, Archiv f Horn. H. xi. 2, 144.
5. A violent face-ache, (prosopalgia, neuralgia of the trigeminus,*)
to these parts, arise from the superior cervical nerves, and send branches as
far as the forehead." (Hirsoh, Spinal-Neurosen. Konigsb. 1843. s. 206. — Watzke.
* The sensitive fibres of the 5th nerve are the seat of prosopalgia 3 . The
facial nerve is purely motor (Constatt. Handb. d. Med. Klinik. Erl. 1843.
iii., 218). We have put the above cases of encephalopathia and hemicrania
under the head of Neuralgia; of the fifth, from a conviction, which our experi-
ments have induced, that it is in these cases it is the affected organ. — Ed. Oest.
Zeit.
Homoeopathic Cures with Colocynth. 361
which had lasted 3 days, speedily yielded to a single dose of Colocynth.
— (Gaspari, Annal. d. Horn. Klinik, hi., 411.) The patient was a
robust man, 40 years of age. The pains were sticking, tensive, and
tearing, extending over the whole left side of the face, appearing period-
ically, aggravated by warmth, motion, and touch, and allowed the suf-
ferer no respite, either by day or by night. The left side of the face
was hot and red. Also thumping pain in the head, as if the left half
were being torn from the right ; toothache on the same side ; general
heat, thirst ; pulse full and hard. No cause could be assigned for the
affection. Colocynth (dose not specified) was given in the evening ;
the patient slept comfortably the ensuing night, and awoke next morn-
ing quite well. On the complaint returning a year afterwards, Colo-
cynth again afforded equally speedy relief.
2. Neuralgia? of the Cceliac Plexus and its Branches.
6. Dr. Schron removed in a sexagenarian, a violent burning pain in
the scrobiculus, with complete intolerance of pressure, vomiting of all
the ingesta, small rapid pulse, and restless tossing about in bed with
Colocynth, one drop of the 30th, repeated after 16 hours. Arsenic
had been tried without benefit. — {Ally. Hom.Zeit. V., 149.)
1. A woman, 50 years of age, had complained for a fortnight of con-
stant disgust at all food, without desire to vomit ; cutting pains in the
abdomen, which often intermitted, and as often returned, and on the
left side of the abdomen a feeling as of a hank twisting round. Also
sleeplessness, heat, violent thirst, bitter taste, copious eructations, loss
of appetite, constipation, frequent calls to make water, with scanty
emission. Colocynth 10 removed the pain. The bitter taste re-
mained, as well as the disgust and anorexia, but yielded to bryonia and
ipecacuanha. — {Annal. d. Horn. Kl. ii., 204.)
8. An anonymous writer (H.) relates a case of a pregnant female,
who was perfectly cured in a few hours by Colocynth 30, of a violent
sticking burning pain in the left side of the abdomen. He looks upon
the affection as an extremely acute inflammation, but whether in the
psoas, kidneys, or spleen, he cannot tell ! Ruoff, in his Repertory even
calls it peritonitis ! It was nothing more than nervous irritation — cir-
cumscribed hyperesthesia of the cseliac plexus. At all events the honor
of the rapid cure belongs to Colocynth. — {Ally. Horn. Zeit. iv., 66.)
9. One cannot conclude from Dr. Kramer's account (Hyyea, i. 30),
nor is it in itself likely, that Colocynth contributed towards the cure of
an affection of the abdomen, of five years' standing, in a duchess^ who,
since her last confinement but one had suffered from almost daily re-
curring sticking pains in the right side of the lower abdomen, extending
to the kidneys and back. There were also hemorrhoids, frequent and
ineffectual efforts to go to stool, constipation, flatulence, distension of the
abdomen, swelling and painfnlness of the lower limbs, cold hands and
feet, disposition irritable and depressed. Sulph., nux, coloc, phosph.,
nux, and again phosph., restored the patient to health in 3 months. In
our opinion Nux-vomica was the specific remedy in this case.
362 s Colocynthis.
10. We regard the three cases which Dr. Schron {Hygea, ix. 503)
gives, as acute catarrh of the bladder, occurring in young women of
thirty, and which he cured rapidly with Colocynth, as hyperesthesias
of some branches of the renal, hypogastric, mesenteric plexus of the
sympathetic, distributed to the urethra, the bladder, and the rectum.
The catarrh was a secondary symptom. The following were the cir-
cumstances : At first, cutting pain in the umbilical region, extending
towards the ovaries ; then desire to pass water, with emission of a small
quantity of cloudy, mucous urine, which soon deposited a mucous sedi-
ment. Next came on pains like labor-pains, in the direction of the
ureters, extending to the upper part of the thighs. Then burning in
the urethra ; the urine could not be retained more than an hour. There
was scarce any intermission of the cutting pain about the fundus of the
bladder. The stools were increased in frequency, and attended with
cutting pains and a kind of tenesmus. Little appetite ; fever towards
evening.
11. We may here notice two interesting cases given by Dr. Y. {Horn.
Behehrungsepisteln, 1837, 43, 44.)
The first was a neuralgia of the internal spermatic plexus, with sym-
pathetic affection of the cceliac plexus, the vagus, and the femoral nerves,
with which it is connected directly or indirectly.
A young woman, 25 years of age, of choleric temperament, had suf-
fered since her 1th year from pains which, proceeding from the region
of the left ovary, extended partly (burning and cutting) towards the
umbilicus, and partly as a painful drawing through the whole right
foot. During the day the pain would not abate for more than an hour
at a time, being worst in the forenoon, 'and being aggravated by motion,
but at night it was frequently scarcely felt at all. When at the worst,
the patient rolled about in bed in spasmodic contortions ; the head be-
came burning hot, the rest of the body icy cold ; the neck and chest
swelled ; the breathing became labored, and consciousness was lost. At
length all the symptoms abated simultaneously with vomiting of a bit-
ter, watery mucus. After such an attack, the pain was much less vio-
lent for several weeks.
A few doses of Nux-vomica and Colocynth sufficed to deliver, the
sufferer from this complaint, which had lasted so long*
^ 12. The second case, singularly enough styled by Y. " Sterno-cwlial-
gia," we consider as a neuralgia of the plexus phrenicus and plexus
gastricus magnus, caused by spinal irritation.
A widow, 44 years of age, had been ill for years. Without assign-
able cause, a constrictive pain was felt in the region of the left false rubs,
at first every four weeks, afterwards every day after dinner. It lasted a
quarter of half an hour at a time, with ceaseless, forcible yawning, .weight
in the chest, and profuse sweat, disappeared at night and in the forenoon,
* We omit the long description of the accompanying (sympathetic) symp-
toms which probably led Dr. Y. to the selection of bryonia, and subsequently
after a violent relapse, of pulsatilla, as having little to do with the cure by the
Colocynth. — Watzke.
Homoeopathic Cures with Colocynth. 363
but gradually increased in frequency and severity, and was accompanied
with turning and cutting in the abdomen. Almost all the medical
lights in the town had plied for four years powders, electuaries, mix-
tures, clysters, blisters, and plasters, but all to no purpose. Y. found
the patient in the following wretched condition : complete loss of ap-
petite — for the last two years she has taken nothing but broth ; a con-
stant bitter taste and much mucus in the mouth ; a stool generally only
once in four days ; catamenia very irregular. The pain has become so
intense that it never entirely subsides either by day or night; and the
violent attacks occur almost every half hour. The patient then bends
herself double, kneels in the bed, stretches herself out again convulsively,
and twists round and round in an agony of tears and groans, &c. If
the pain leaves the side and belly, the chest is seized with a horrible
constriction ; the patient is seized with unutterable anxiety, and feels as
if she was dying. The limbs are cold ; the pulse small and irregular ;
and the whole body drips with a cold sweat ; also almost constant sleep- /
lessness, extraordinary weakness and lassitude, great emaciation, des/
pairing frame of mind.
Under the repeated use of colocynth 3, bryonia 3, and arsenicum 30,N
complete recovery ensued in two months ; and after two years she con- \
tinued to enjoy uninterrupted and robust health, without the slightest
trace of her former malady. (It seems to us that the remedies which J
were employed besides the Colocynth, could have scarce any if at all /
contributed to the cure.)
13. Dr. Most of Rostock communicates the following case (Ally.
Med. Zeit, May, 1834):
An aged single woman had suffered for a fortnight from periodical
pains in the abdomen, headache, nausea, and violent pulsation in the
region of the spleen. The pulsation began towards evening, and con-
tinued three or four hours. Under the use of effervescing powders the
abdominal pain had disappeared in a week ; not so, however, the peri-
odical headache and pulsation in the belly, which (though the radial
pulse was unaffected) was perceptible not only to the touch, but to the
sight. In some of these paroxysms the agony rose to distraction.
When they passed off, the patient felt quite well. The Tinct. Voter.
Ammon. employed for fourteen days, alleviated the difficulties, but the
beating continued unabated. Constipation also occurring, Most sus-
pected the existence of infarcta (!) and prescribed Tart, tart., rhubarb,
and flowers of sulphur, ordered the patient to drink tea made from va-
lerian and senna, and had the balsam of sulphur rubbed into the side.
When he saw the patient again after eight weeks, she was freed from
her whole complaint ; but not from the medicines mentioned above, but
from a household simple— Colocynth-brandy. Having drunk this four
times, she passed, amid violent pains in the belly, and diarrhoea, seven
lumbrici, the expulsion of which was followed by complete recovery. ^
Does not the periodical type of this affection, with the complete in-
termissions, distinctly point out its nervous character ? Was the abdo-
minal pulsation — arising from increased innervation, directed on the
364 Colocynthis.
splenic arteries — the necessary result of the irritation from the worms ?
May we not rather suppose, that the whole complaint, including the
worms, was the product of an abnormal influence of the cceliac plexus
on the digestive apparatus ? Was not the headache to be regarded as
a reflex action on the central termination of the sympathetic system ?
"Why did not the parasites yield to the laxatives, e. g. the rhubarb, pre-
viously employed ? In vermicular affections what is it that determines
the choice of the anthelmintic ? Are we mistaken in saying, that, in
the case related above, the headache, the abdominal pulsation, and the
lumbrici would have been proof against Cina, anel Sabadilla, and Spi-
ff elia too ?*
By far the most frequent use that has been made of Colocynth,
has been for the cure of colics. Indeed it has been employed too in-
discriminately in this way, and has become to the adherents of the spe-
cific method, what opium is in the old school. Nenning {Annal. d.
Horn. Klinik, ii. 256) gives several cases.
14. A servant-maid had been tortured with a violent colic for ten
days. The pain lasted day and night ; she cried out, bent double, and
rolled about in her bed. Every imaginable domestic remedy had been
tried in vain, and the patient's death wasexpected from hour to hour.
One drop of the 24th dil. of Colocynth produced almost instantaneous
relief. A drop of the 30th dil. had as prompt an effect in a similar colic
occurring in a boy of 13.
15. A cabinetmaker, 50 years of age, undersized, of choleric temper-
ament, was seized with colic, without known cause. It began at ten in
the morning, and continued till midnight, with more or less intermis-
sions. He was hot and thirsty, vomited repeatedly all iugesta, and had
not a stool oftener than once in five or six days. A single dose of Co-
locynth 24 removed the complaint, which had lasted fourteen days,
notwithstanding the use of laxatives and anodynes.
16. An unmarried female, 42 years of age, was seized, after a fall on
the ice, with burning in the left side of the abdomen and groin ; the
pains abated somewhat under the use, during four weeks, of ointments,
poultices, and mixtures. She was so unfortunate, however, as to fall a
second time, when violent sticking was experienced in paroxysms in the
parts which had previously suffered. The attacks came on once an
hour, or once in two hours, and lasted a couple of minutes at a time.
Allopathic remedies (chiefly drastic purges, which brought on painful
* Cruvelhier states ( Univ. Lex. d. pr. Med. u. Chir. Art. Entozoa) that he
knows of a domestic remedy of great efficacy against these worms, especially
in persons past the age of 14. It is Colocynth, so highly prized by the ancients,
for this purpose. He administered Colocynth-brandy internally to two adults,
and caused, at the same time, an ointment, consisting of powdered Colocynth
and lard, in the proportion of a drachm to the ounce, to be rubbed into the
hypogastric region. This was followed, in both cases, by the expulsion of
these animals in great numbers ; and the symptoms complained of, — which, but
for their periodicity, might have been set down to inf animation of the heart or
great vessels, — speedily disappeared. It is a pity thatCruveilhier has not des-
cribed these cases more minutely. Their resemblance to the case in the text,
and to nervous affections, is, however, apparent, even from this imperfect ac-
count. — Watzkc.
Homoeopathic Cures with Colocynth. 365
and bloody stools) were used without effect for twenty-two days ; the
pain continually increased in severity. Nenning found the abdomen
large and tense ; the left side and groin felt sore and bruised when
touched, as if something had been torn there ; the tongue was dry ; ap-
petite small ; frequent bitter eructations ; frequent desire to urinate, with
discharge of abundant pale yellow urine. A single dose of Colocynth
30, sufficed to remove the paroxysms of pain. Arnica removed the
remaining tenderness of the left side.
17. A man, 49 years old, after drinking a quantity of wine — a be-
verage that never agreed with him — was seized on the following day
with constant retching, not relieved by vomiting, and sticking burning
pain in the left lumbar region, drawing towards the umbilicus, so vio-
lent as to deprive the patient of all rest, whether in or out of bed ; he
rolled himself like a ball, sometimes all but resting on his head, some-
times kneeling in the bed, but without relief, whatever the position he
assumed. Having removed the sickness with ipecucanaha 3, Kenning
ordered Colocynth 24, which effected a complete cure in three days.
18. Its effect was more rapid in the case of a young man, of weakly
constitution, who, as he supposed, from catching cold, suffered such ex-
cruciating pains in the belly, that he thought he should go wild. He
cried out constantly for help ; he felt as if his intestines were being cut
in pieces. Occasional intermissions were succeeded by more violent
paroxysms. This had lasted the whole night. Bitter drops, the Spi-
ritus Hoffmanni, and essence of caraway had no effect. Nenning then
gave half a drop of tincture of Colocynth, and in half an hour all pain
was gone.
19. Violent abdominal pain, making the patient bend herself double,
with inclination to vomiting and diarrhoea, occurring after catching cold,
in a sickly girl, 19 years old, at the commencement of the monthly pe-
riod, was immediately assuaged by a dose of Colocynth 30, and disap-
peared entirely in a few hours.*
Our colleague, Dr. Weinke, contributes another case of menstrual
colic, cured by Colocynth.
* After Nenning has communicated cases of this character to the Annal.
der horn. Klinik, he complains in the Ally. horn. Zeit. xv., 119 (notwithstanding-
he had in the meantime alternated colocynth and chamomile every half hour,
in cases of colic with constipation " with the best results") about the uncertainty
of homoeopathic remedies for colics particularly and especially of colocynth.
Allopathy, with its purgatives, clysters, frictions, and baths is by far more effi-
cacious in such cases ! " Where," he exclaims " can the homoeopath find a
sure and certain laxative ?" It seems to us that the uncertainty can be fairly
charged neither upon Homoeopathy nor upon colocynth, but rather belongs to
Nenning's diagnosis, of which we have not derived the highest idea from read-
ing the remarks accompanying the foregoing cases inthe Annalen. When the
colics which accompany a tubercular state of the peritonaeum, and the forma-
tion of tubercular ulcers in the intestinal mucous membrane, notwithstanding
their resemblance to the colics of colocynth, still refuse to be cured or relieved
by that drug or by any other, this fact will hardly excite wonder in a physi-
cian, except perchance, in one, who cannot spy the tuberculosis behind the
colic. — Ed. Oest. Zeit.
366 Colocynthis.
20. Josefa Binder, 33 years of age, of lively temperament, following a
sedentary occupation, accustomed to take wine in moderate quantities,
had for some months experienced, 2 or 3 days before the catamenia
(which were normal in quantity), violent cutting pains below the navel,
from which they extended towards the flanks, and the internal genital
organs, only ceasing now and then for half-an-hour ; they disappeared
when she became warm in bed, and were accompanied by cold feet.
The stools were pap-like, and occurred once or twice a day, with griping.
Drawing the thighs up to the body relieved the abdominal pain. A
single drop of Colocynth 1, on sugar of milk, removed the pain in the
course of an hour, and the menses came on during the night without
any further inconvenience.
21. Paroxysms of colic in a lying-in woman most frequently at
night ; cutting as if with knives in the abdomen, preceded by discharge
of flatulence, and accompanied by chills, violent stitches in the region
of the right ovary, and tearing in the foot ; during an evacuation, grip-
ing constriction in the bowels. Th. Rueckert cured this case speedily
with Colocynth 12.
22. Our colleague, Dr. Bohm, cured radically with Colocynth 3, at-
tacks of colic, with pressure at the stomach, flatulence, eructations, and
mucous diarrhoea, in a man of 54, subject to haemorrhoids ; the colic
came on daily, and was brought on by taking food even of the lightest
description. The patient had undergone the water treatment of Gra-
fenberg for three years, with partial amendment, toon after the first
dose of Col jcynth, he was seized with a more violent colic than he had
ever experienced. Ten months after he had experienced no return.
23. A g rl, 11 years old, was suddenly seized, without assignable
cause, with the most violent pain in the abdomen, which refused to
yield to the purgative and anodyne remedies prescribed at home.- The
pain increasing every quarter of an hour, Dr. Bethmann was sent for,
and found her in indescribable agony, bent double, rolling about in the
bed, howling and whining ; abdomen drawn in, sensitive to the slightest
pressure ; pulse small, scarcely perceptible ; skin dry, hands and feet
cold. She dared not take more than a few drops of milk and water at
once to quench her burning thirst ; if she took more, vomiting ensued.
Soon after taking adose of Colocynth 24, she fell into a calm sleep, and
awoke in the morning quite well.
She had previously been liable to slighter attacks of the same nature,
but after this remained, so long as Dr. Behtmann kept her in view —
fullv 3 years — quite free from them. (Annal. d. Horn. Klinik, Hi.
419.)
24. In the 3d number of the 5th vol. of the Archiv, page 27, we
find a remarkable cure by Colocynth of a chronic tympanites, with pe-
riodical attacks of colic.
A young woman had been in bad health ever since her last confine-
ment, in which she had had a profuse haemorrhage. The abdomen was
so swelled and tense, that she seemed pregnant. She also suffered from
frequent paroxysms of colic, and had lost much in strength. She had
Homoeopathic Cures with Colocynth. 367
been treated unsuccessfully for two years by allopathic means. On the
29th Nov., 1823, Dr. H. of Z., who had previously treated the patient for
half ^a year with mixtures, being called to her in the evening, found her
in the following condition : The most violent pains in the whole abdo-
men, as if the bowels were bruised between stones ; she can only lie
doubled together; abdomen swelled and tympanitic; countenance pale,
sunk, and pinched ; frequent retching ; fainting fits ; unutterable an-
guish ; constipation.
_ After a dose of one drop of Colocynth 12, ensued a notable aggrava-
tion of the pains for some minutes, which, however, soon entirely ceased.
The patient fell into a sleep, from which she did not awake till next
morning. The tympanites disappeared in a few weeks. H. observed
the patient for two years, during which time there was no return of the
colic. Doubtless the tympanites was dependent on the neurosis, and
of secondary importance.
25. Dr. Hering removed the colic of the West Indies (dry belly-
ache), which is dreaded both on account of the violence of its attack
and its tendency to relapse, and to bring on secondary affections (para-
lysis of the limbs, chronic diarrhoea, &c), in three or four days, by the
alternate use of globules the size of mustard-seeds, of Colocynth 30
and of black coffee, without ever leaving any secondary disease. — Ar-
chivf. Horn. H. xiii., 3, 69.
Hering says it was from these cures of colic that he was first led
to see the necessity of repeating the remedy in alternation with its an-
tidote. We must confess that we have no great opinion of this alter-
nating system, and that the necessity for it is not at all apparent to us
from these cases of Hering ;for they furnish no evidence of the efficacy
of Colocynth. The aggravation which sooner or later succeeded the ad-
ministration of the globule is simply referable to the process of develop-
ment of the colic, rising and falling periodically, till it reached its acme.
Nor do we regard the black coffee as a curative or specific agent, but
it masked the abnormal sensations either completely or partially while
its effect lasted ; in short, it did nothing but make the disease run its
course with less torture to the patient. The pain was renewed each
time, not from the globule of Colocynth having been swallowed, but
from the anodyne effect of the coffee having passed away.
26. The following account of a case of an abdominal neurosis, com-
plicated with a prosopalgia, related by Gtaspari (Annal. d. Horn. Klin.
iii. 19, et seq.), is interesting in more than one point of view.
A young woman, 24 years of age, fell ill after catching cold, with
high fever, sticking in the chest, and headache. Six bleedings and
many mixtures freed her in six weeks of this acute attack, but induced
a worse and chronic one, on which the resources of art were fruitlessly
expended during three years. Gr. undertook the case in the following
state : — Emaciated to a skeleton ; skin harsh and clay-colored ; formi-
cation and restlessness of the whole body ; extreme weakness of the
limbs ; giddiness, making her footing insecure ; want of memory ; pas-
sive pain in the brow and temples, most tolerable in the recumbent
368 Colocynthis.
posture, aggravated by sitting up and walking ; pale contracted features;
watering of the mouth ; desire for milk; eructations and risings of a
sweetish fluid after eating anything. The eructations continued with
anguish, pain and pressure at the scrobiculus, for half an hour or an
hour after eating, when the food came up, and she experienced a sense
of emptiness and cramp ; rumbling, pinching, burning, and sticking in
the abdomen. A stool every three or four days, whitish and hard ; the
catamenia had not appeared for three years, the duration of her com-
plaint.
But little benefit was derived from aconite and calcarea, during nearly
four weeks. There now occurred, apparently from catching cold, vio-
lent tearing, burning, and continual sticking in the left half of the face.
The pains became worse on contact, and made her cry out. The pa-
tient could get no rest, and passed the night without sleep. The symp-
toms enumerated led Gaspari to Colocynth. It and sepia, to which he-
afterwards had recourse, effected a complete cure. The menses returned ;.
and he says, in conclusion, that the patient, who previously could only
be regarded as the certain victim of death, has ever since enjoyed unin-
terrupted good health.
Are we mistaken when we set this complaint down as fundamentally
a nervous one? May not the abdominal affection, which undoubtedly
made a near approach to organic change, be referred to depraved inner-
vation ? What was the relation of the prosopalgia to the neurosis of
the abdomen? Did the peccant matter from the gastric branch of the
vagus spread to the trigeminus ? Was the curative action of the Colo-
cynth limited, as Gaspari seems to think, to removing the neuralgic pain
in the face ? or may we not rather suppose it to have played the prin-
cipal part in the removal of the whole complaint V
27. Colocynth has been recommended by many authorities, and
much employed in dysentery. Dr. Mosbauer derived great help from
it in an epidemic dysentery (Archiv f. horn. U., vi. 3, 18). Muiilenbein
also assures us that he cured several cases of diarrhoea and dysentery
by its means (Archiv f. horn. Hei.l, vi. 3, 78). Tincture of Colocynth
employed by Rau ( Ueber den Werth des horn. Heilverf., 1st Auf. s.
99), effected speedy cures (in 2 days) in sporadic dysentery. He found
it most useful when it was accompanied by violent colic pains. Accord-
ing to the experience of Pauli (Hyy. iii. 139), Colocynth is most adap-
ted to those kinds of dysentery in which there is great pain, and scanty
stools. Dr. Conters (Hyg. iii. 269) found it effectual in an epidemic
where there were violent tearing pains in the belly, forcing the patient
to bend forwards, incarcerated flatulence, and frequent stools streaked
with blood. Rtjmmel also resorted to it with success in a case of dysen-
tery, to remove the pains (Annal. d. horn. Klin.'w, 322.) A friend of
Leo Wolf, at New York, employed Colocynth with such extraordinary
success in dysenteries, as, he assures us, not to have lost one single pa-
tient in three years (Ifleinerfs Repert., 1832, ii. 155).* None of these
* Gross's assertion {Archiv fur horn. Heilk. xv. 1, 97) that Colocynth had been
of no service in his hands in common dysentery, with violent cutting in th«
Homoeopathic Cures with Colooynth. 369
gentlemen, however, have given us a detailed description of a dysentery
cured by Colocynth.
We are inclined to think that good effects are to be expected from
Colocynth in dysentery (speaking generally), only so long as the hyper-
sesthesia of the intestine, and especially of the rectum, — which, according
to Verger, Chauvin, Fink, Paterson, and others, constitutes the cause
and essence of the disease, — is still predominant, and is not overcome by
the (consecutive) inflammatory process ; i. e., so long as the dysentery
presents the character of a neurosis. Against the inflammation, with
its organic products — in short, the fully developed form of dysentery-
it will be of much less service.
III. Neuralgia of the Lumbar and Femoral Nerves, and
their Branches.
1. Lumbago.
28. A man, 54 years of age, tall and thin, given to drinking, and
a sufferer for some years past from dyspeptic and severe hsemorrhoidal
complaints, fell ill after exposure to cold, and was treated without suc-
cess for five weeks by several physicians. Ruckert undertook the case
on the 15th February, 1817. The following is the account of the pa-
tient's state: —
Violent thumping pain in the whole costal region ; tension of the
integuments from the umbilicus to the thigh. He cannot move from
the spot, nor put one foot before the other ; when he tries to walk, he
feels as if all the tendons were torn and cut to pieces. He cannot even
stretch his feet out when he lies down. The easiest posture is sitting
bent forward. Frequently he cannot make water, which is often tinged
with blood. He has some appetite, and regular bowels ; sometimes
feverish towards evening. Great irritability and moroseness. Riickert
first administered a (superfluous) dose of aconite 6, and, after twenty-
four hours, of Colocynth 12. By the 20th his general state was much
improved. After a fresh dose, till the 24th, the pains in the abdomen
had quite disappeared ; but the patient could not yet walk. He now
got a drop of digitalis-purpurea. At the end of February he could
go about the room without a stick. On the 9th March he was able to
go out. Dr. R. now gave him, as a prophylactic (!), another dose of
Colocynth. From this time forward he enjoyed uninterrupted good
health. — (Annalen d. Horn. Kl. i. 292.)
Ruckert entitles this case " chronic psoitis ?" Ruoff and Kirsch
have, in their Repertory, left out the note of interrogation. By many
the complaint will be held to be chronic nephritis. But the affection
of the kidneys was secondary. The lumbar plexus, which supplies
the iliacus internus and the psoas, was plainly the part primarily
affected.
bowels, and almost incessant scanty discharges of bloody mucus, and subse-
quently of organic shreds, amounts simply to th« assertion thatjbe drug 13
not homoeopathio to such case*. — Ed. Ottt. Ztit.
370 ColocyntMs.
2. Ischialgia.
29. The Countess , 58 years of age, fair, and remarkably ro-
bust, the mother of three children, was attacked, -when 22 years of age,
with sciatica, in consequence of repeatedly taking cold, and, notwith-
standing that she tried every remedy, not excepting the actual cautery,
she limped from that time so much as to making walking difficult and
painful in the highest degree. The last medicine used was cod-liver
oil, which she had taken for several weeks by tablespoonfuls. The
bashful Countess would not permit an accurate manual examination of
the painful hip, but she described the pain in the thigh as pressive,
constrictive, on walking sometimes sticking. On attempting to walk,
she felt a strong tension extending below the knee, so that she could
not place the sole on the ground, but only the toes. The heel remained
a full inch from the ground.
Colocynth 18, a drop every eight or ten days, had not, after several
weeks, effected the slightest improvement. After Colocynth 12, she com-
plained of a burning feeling in the hip-joint, which, after lasting five
days, went off, but was not followed by any amelioration of her state.
A second dose of the same dilution again caused this burning sensa-
tion ; and this time, when it disappeared, the patient was certain she
could perceive a lessening of the pressive constrictive pain in the hip-
joint. A dose of Colocynth was administered every eighth day with
slow improvement. After fourteen weeks, the limping was so far di-
minished as that the heel remained only about half an inch from the
ground. In eleven weeks more, she could walk as well with the af-
fected limb as with the other, except that it sooner became tired during
a long walk.* — (Schwarze, Horn. Heilungen, 1836, p. 125, et seq.)
If this cure was entirely due to the Colocynth, of which we have
not the slightest doubt, stronger doses of the remedy might have has-
tened it.
30. A woman, 27 years of age, was seized, after exposure to cold,
with tearing pains in the right leg, most severe below the knee and in
the calf, extorting screams. Warm drinks, sal-ammoniac, with tartrate
of antimony, effected but little change for the better in eight days.
The whole thigh was now swollen ; the leg lay stretched out, incapable
of motion, the foot turned outwards, lengthened by nearly an inch ;
the right side of the posteriors flaccid. Neither the trochanter nor the
groin were painful on pressure ; but the least attempt at movement
caused excruciating pain. Ung.-JVeapol. Liniment.-volat, Ung.-
nervin , repeated blisters, mixtures of sal-ammoniac and saltpetre,
calomel, sulphuret of gold, guaiac, corrosive sublimate, quinine, and
opium, were used in vain. At the end of the sixth week, the whole
thigh was swollen to double its proper size, and extremely sensitive to
the slightest touch. Even the tread of a foot in the room, and ap-
proaching her bed, caused pain. The patient felt as if her leg were
* A relapse was cured by Sciiwarze in three weeks with Arsenic 18. — Watzke.
Homoeopathic Cures with Colocynih. 371
moved convulsively to and fro. She ate nothing, had grown very thin,
had much fever, and passed the night in screaming.
After a single dose of Colocynth, the patient passed a tranquil night ,
— the first for many weeks ; the pains abated ; in a few days she could
sit up and allow her limb to be moved. Silicea, given after twelve
days, completed the cure. — {Thorer's Beitrdge, iv. 9.)
31. Lobethal (Allg, Horn. Z. xiii. 115) treated a similar case. A
strong man, about 30 years old, who was exposed by his occupation
to frequent chills, had been attacked, eighteen months before, by coxitis,
and since then had been entirely confined to bed. The affected foot
was shortened ; its muscles shrunken ; the pain in the hip constant and
intolerable. Colocynth 30, every second day, did much good. Lobe-
thal supposes this to have been morbus coxarius in the third stage.
We take it, notwithstanding the difference in the position of the limb
in this and the preceding case, to have been ischialgia. 'The morbus
Coxarius is not within the sphere of action of Colocynth.
32. One of the most splendid cures to be found in homoeopathic,
and perhaps medical literature, was effected by Dr. JEgidi, {Ar-
chiv f Horn., H. vii. 109), by means of Colocynth, in the following
case : —
A young lady, 21 years of age, experienced, in August, 1824, a
displacement of the ossa pubis from a blow on the symphysis. After
a speedy cure, nephritis came on, and the urine was finally discharged
mixed with pus. The antiphlogistic treatment employed did not re-
move, but ameliorated her state ; so that, by the end of March, 1825,
there only remained a feeling of numbness and paralysis from the
small of the back to the thigh, violent long -continued pains about the
symphysis pubis on the slightest touch, distended abdomen, and pe-
riodical attacks of colic*
In January, 1826, she grew much worse from over-exertion. She
could now only sit on the right nates. The affected limb was stretched
out with the toes turned inwards. From time to time (11 or 12 times
a day) she felt, for an hour or two together, agonizing pain proceeding
from the region of the left kidney down the corresponding limb as far
as the outer malleolus, with constrictive pains, like those of labor, in
the abdomen, forcing screams from the sufferer. Adjoining the sacro-
iliac articulation and the symphysis pubis, osseous tumors had formed,
which, on being touched, were the seat of burning pain ; abdomen
tympanitic, tender to the touch; vesical tenesmus with abundant
secretion ; urine clear while the pain lasted, at other times reddish,
with a gravelly, whitish flocculent deposit ; bowels irregular, sometimes
no action for a long time, sometimes several tough and slimy stools in
a day ; at times burning pain at the anus during the evacuations,
quickly followed by a sensation of weakness and paralysis of the anus ;
appetite small ; periodical and violent pain in the chest, and still more
* If these latter symptoms were accompaniments of the renal affection, we
should very much doubt its inflammatory character. — Ed. Oest. Zeit.
372 Colocynthis.
violent headache on the left side ; great depression ; proneness to
faint ; troubled sleep ; frightful dreams ; alternate shivering and heat;
excited state of mind; countenance expressive of suffering; great dis-
inclination to speakiny ; tearful mood ; irregular menstruation.
Leeches, hyosciamus, aqua laurocerasi, and opium, were tried with-
out benefit for several weeks. Nor was the result of the first 1 1 weeks
of the homoeopathic treatment, during which she got cocculus, sulphur,
nux, capsicum, aurum, mercurius-solub., and conium, more favor-
able.
On the 5th of June, resort was had to the actual cautery. The
suppuration which ensued relieved most of the sufferings, but only for
a few weeks, when, with a diminution of the discharge, the whole train
of symptoms returned in all their severity, and on the wound beginning
to heal up, the patient's state became far worse than before the appli-
cation of the cautery. Her general feelings were deteriorated ; she
was pale and her eyes sunken ; a slight cough and daily fever, worse
in the evenings, came on. The wound was allowed to cicatrize, and a
nourishing diet, quinine, Iceland moss, gentian, and barley-water, &c,
were prescribed. In a few weeks the strength recovered, and the fever
disappeared, but the oriyinal complaint remained untouched. Warm
baths, sal-ammoniac, chloride of gold, were tried for some weeks, but
always without relief.
Under these circumstances, Dr. JEgidi again resorted to Homoeo-
pathy. The patient took, on the 8th September, at 9 a.m., one drop
of Colocynth 6, in a teaspoonful of distilled water.
In the evening the sufferings of the patient increased dreadfully.
She could not find ease in any posture, and was wrought up nigh to
distraction. A violent tearing pain shot throuyh the whole brain, and
became intolerable when the upper eye-lids were moved ; in the riyht
eye-ball pain as from a knife, extending to the root of the nose ; empty
eructations, causing palpitations and spasmodic action of the fauces,
with constant inclination to vomit ; periodically a dreadful cutting in
the abdomen, proceeding from the left renal region, spasmodically
drawiny the left thiyh up to the body, and forciny the patient to bend
herself completely forward.
Rightly ascribing the paroxysm to his having given the medicine in
an over-dose, Maim gave a spoonful of black coffee now and then, and
put a solution of camphor to the nostrils. In a few hours the pain
subsided, the patient fell asleep, slept soundly the whole niyht, and
awoke quite well. On waking she said a peculiar indescribable feel-
ing of comfortableness pervaded her whole frame. She could bend
and stretch the left limb, tread with the left foot, and walk without
support.
The next morning she proceeded on foot to visit her physician. She
told him she felt perfectly well on waking, and her first attempts at
walking in her room proving successful, her overflowing joy would not
allow her to remain in the house, and she felt her strength increase
with every step she took in the open air. So saying, she raised the
Homo30j>alhic Cures with Colocynth. 373
sound foot from the ground, and turned round and round on the
affected one. No farther medicine was required ; she daily improved ;
even the osseous tumors disappeared in a short time, and she henceforth
enjoyed perfect health.
33. Our colleague, Dr. Bohm, removed with Colocynth 3 anlschias
postica, which had attacked a hearty, healthy man, of 40, without as-
signable cause, with violent pain, extending from the trochanter to the
ancle, which had for 12 weeks returned every week, and lasted 20 or
30 hours with extreme intensity. Rhus-tox. had been tried without
effect. The paroxysm returned once, but in a feeble degree, and went
away permanently under a continuance of the Colocynth.*
We close this chapter with a critical review of a few cases, recorded
in our homoeopathic literature as Colocynth-cures, but which we con-
sider as
IV. Doubtful or Rejected Cases.
34. Dr. Schron [Ally. horn. Zeit. v. 150) gives the case of a woman
who was suddenly attacked with incessant vomiting, first of food, then
of a greenish fluid, and diarrhoea with rapidly recurring stools, becom-
ing constantly thinner and less colored, and attended by violent stick-
ing, cutting, colic and cramps in the calves ; suppression of urine ; rapid
prostration. Colocynth 18, every two and afterwards every three
hours, removed the attack in twenty-four hours.
It would be an exceedingly easy thing to fit this case into our Colo-
cynth-schema ; we need only regard the cholera, with Pinel, Hilde-
brandt, Rast, Rathke, and others (See Radius, Cholerazeitung, B.
l), as a ganglionic neurosis, an affection of the Plexus coeliacus, an
erethism of the sympathetic, &c. Besides this, the cholera has been
cured with many remedies to which anti-choleric virtues have been
ascribed with far less probability. But our provings upon the healthy
have brought to light too few symptoms like those of cholera, and
Schron's single relation is too isolated a fact to authorize us to consider
his case as anything more than an instance of that disease running a
natural but rapid course towards recovery.
35. A plethoric brunette of 30 aborted at four weeks; inconse-
quence of passion, the lochia had ceased for four hours ; head hot ;
scrobiculus and abdomen painful to the touch ; delirium alternating with
sopor, the eyes half open ; constant desire to get out of bed. Colocynth
30 towards midnight; relief in three quarters of an hour, and in the
morning reestablishment of the lochia and recovery. Melicher,
(Attomyr, Brief iib. Horn. i. 153.)
Ruoff calls this Puerperal Fever ! To us it appears simply an ar-
* Attomyr (Arckiv, xi. 2, 118), cured three cases of coxalgia, by means of
Colocynth, in a few days, but, alas! does not give us the particulars. _ Dr. Y.
also (Horn. Bekehrungsep. 1837, 29) mentions having cured an ischialgia of
two years' standing with nux and Colocynth in a short time, but neither does
.be give us a description of the disease. — Watzke.
374 Colocynthis.
terial orgasm, with cerebral congestion, the rapid disappearance of
which owed little to the dose of Colocynth.
3G. Hoffendahl (Archiv xii. 2, 172) had the wonderful good
luck to meet three patients, two women and one man, in a single day,
suffering from psoitis, with such violent pain in the right thigh that they
could not walk, and to cure them each within twenty-four hours by a
single dose of Colocynth 30. These were hardly cases of psoas in-
flammation, as our good colleague conjectures, but rather transitory at-
tacks of rheumatico-ischialgia.
37. Kopp {Denkwurd. iv. 329 und 338) cured several cases of pa-
ralytic weakness of the legs with Colocynth, where there were affection
of the head, somnolence, confusion, torpidity of the bowels and dispro-
portionably thin legs — a group of symptoms having direct relation to
diminished or depraved nervous influence — paresis of the femoral
nerves ?
Can Colocynth, in the extreme limits of its operative sphere, produce,
on the one hand, a congestive, hypersemic and inflammatory condition
(especially of the brain and mucous membrane of the ileum and rectum) ;
and on the other hand, cause and cure paresis (especially of the lower
limbs) 1 Satisfactory conclusions on this subject may be deduced from,
the chapter of experiments on animals.
38. Gross {Archiv fur horn. Heilk. xii. i. 88) relates the following
case, which has caused the repertory-makers to insert erroneously stiff-
ness in the elbow as cured by Colocynth. A weaver fell upon his arm
from a tree upon an old stump nine years before ; the arm continued
stiff and sore, and two years afterwards five ulcers appeared, which re-
fused to heal, but in the course of several years became gangrenous and
discharged several pieces of bone. The arm was swollen, and a pressing
tearing pain tormented the patient, particularly at night. He was
finally treated for a year in an allopathic hospital ; but as the difficulty
seemed constantly to become worse, a council of six physicians and sur-
geons decided upon amputation, which, however, the patient would not
submit to, and left the hospital. Under the use of arnica the pains
disappeared in a week ; silic, calc, and sulph. cured the ulcers in the
course of several months, and a single dose of Coloc. removed the remain-
ing stiffness of the arm in a short time.
We are of opinion that the disappearance of the stiffness was a sim-
ple consequence of the healing of the ulcers, and not in the least attri-
butable to the Colocynth.
39. Kramer (Hygea 1, 25) gives us a case, but whether Coloc.
had any and what share of the credit in the cure of an affection in which
nux, aeon., ars., carb-an., carb-veg., and phosph. were employed in ad-
dition, cannot be gathered from his account.
The patient had suffered for four years from congestion of the liver (?)
piles, constipation, flatulence, inflation of the abdomen, violent pe-
riodical pains, drawing through the middle of the chest to the hip. The
paroxysms of pain lasted an hour, and were accompanied by asthma,
redness of the face, very rapid pulse, and dulness and aching of the
Homoeopathic Cures with Golocynth. 375
head. The whole affection disappeared within six weeks from the use
of the above-named remedies. For four years he had used laxative,
opening, and purgative remedies, bitter extracts and acids, and mineral
waters, in vain.
40. Schellhammer (Archiv fiir horn. Heilk. xvi. 2, 79) employed
Coloc, with ars. and seneg., for the cure of dropsy of the chest and ab-
domen, ensuing after the disappearance of itch from external appli-
cations. The previously administered .sulph., which had reproduced the
itch, doubtless had most to do with the cure, and the employment of
the subsequent remedies was superfluous.
41. Hechenberger's cases (Colocynthologie, 25) almost all belong
in the category of doubtful instances of the efficacy of Golocynth. We
give the concisest possible sketch of them ; they do not furnish much in-
formation, as the author not only administered other remedies, but even
combined them with the Colocynth.
42. A lively servant girl, set. 33, small, irritable, irregularly menstru-
ating, was seized with a gastric nervous fever, with thickly-coated, clam-
my tongue, nausea, constipation, inclination to vomit, meteorism, at-
tacks of fainting and delirium. Tincture of Colocynth with spiritus
Hoffmanni, rinsing the mouth with diluted vinegar, mustard plaster on
'the small of the back, and subsequently Colocynth in a decoction of ar-
nica, with sulphate of quinine, brought the patient to the stage of con-
valescence in ten days. We think, however, that the cure depended
upon Hoffmann's liquor, arnica and quinine.
43. A P tyalismus Suecicus — frequent pyrosis with cardialgia, fre-
quent vomiting of food, emaciation, &c. — was cured in three weeks, dur-
ing the employment of a mixture of a decoction of quassia and the
tinctures of Colocynth and opium, with evacuation of soft, painless stools,
and extraordinary discharge of wind. The patient, a poor, sickly wo-
man, a weaver, had been sick for two months, and during the treatment,
left her occupation, was forbidden to eat potatoes, and took moderate
exercise with easily digestible food. It seems to us that this case would
have got well quicker under th 3 diet and hygienic means without the
mixtures, the Colocynth having done little towards it, though the symp-
toms which attended its use are similar to those produced in our prov-
ings upon the healthy.
44. A man of 50, intemperate both in drink and passion, suffering
for years from abdominal congestions (?), and annually visited with fre-
quently recurring attacks of asthma, colic, gout in the feet, and the vene-
sections and mixtures consequent thereon, was radically cured by the
continued use of Colocynth. The disorder in this case is so slightly in-
dividualized, that we learn little or nothing from the relation. Doubt-
less the cure would have been considerably hastened if, instead of delug-
ing the patient with nauseous dandelion-tea, he had given him good
spring-water to drink.
45. We learn little more from the next two cases. A'tavern-keeper,
strong, choleric, and high-tempered, subject to a violent ischialgia which
376 Colocynthis.
had resisted all remedies, resorted to tlie purgatives of a quack as a re-
fuge from the actual cautery, and was cured.
46. A miner, attacked after a bilious fever with a painful swelling
of the right thigh and leg, had been fruitlessly treated for a year by
doctors and surgeons. When they informed him that the enormous
swelling was about to suppurate, he fled for consolation to a cobbler,
who, to the astonishment of everybody, cured him rapidly and without
any subsequent trouble by a remedy containing a portion of Colocynth
tincture.
47. A miller, set. 36, was suddenly seized after a violent fit of anger
with stitches in the side and dreadful pain in the right thigh and hip-
joint, so that he could neither stand nor go. HECHENBERGERsent him
half a drachm of tincture of Colocynth in half a pound of decoctio gra-
minis, to take a tablespoonful every hour. He heard two days after-
wards that the patient had entirely recovered, the most unexceptionable
case which we find in our colleague's whole book !
48. A woman, set. 43, of an irritable temperament and jaundiced
appearance, mother of thirteen children, had had wandering pains in
her limbs for two years. During the preceding winter gastric difficul-
ties had been added, until afeb?-is cacochymica and atonic dropsy set
in. The respiration was oppressed, feet and hands, face and abdomen
much swollen. The author considers the case as a crisis erronea of an
erysipelas of the face, which had been present some days before the ap-
pearance of the dropsy, and had been unobserved. He prescribed a mix-
ture of 10 ounces of decoction of Graswurzel, 10 grains sulphate of qui-
nine, 2 drams of tincture of Colocynth, and 15 grains of unwashed, sudo-
rific antimony, of which the patient was to take a teaspoonful every hour,
and to drink wine and water. In a week he heard, to his astonishment^!)
that the patient was perfectly cured. What a remarkable ability he
has displayed, however, in assigning to each of the components of his
formidable mixture, the part which it performed in effecting the cure ! !
49. A phlegmatic, cachectic, emaciated proprietor, set. 39, had been
troubled for five years with pain in the stomach, heartburn, constant
dull pain under the right ribs, and about the pylorus and navel, and
constipation — a stool once in four or five days. The malady was ag-
gravated one or two hours after every meal, and the ingesta were fre-
quently vomited with painful retching. Stools of scybala, with burn-
ing pain in the small of the back.
Castor oil and Kirsch-water, tea of Graswurzel, Neapolitan salve, and
tincture of opium, ameliorated the condition somewhat in six weeks (/).
Small doses of tincture of Colocynth, disguised first in Castor oil, and
subsequently by syrup of buckthorn-berries and Seltzer-water, cured
him perfectly in eleven months, a daily stool containing black blood
having come on. Is it possible that any one can put faith in a cure by
Colocynth, that it took eleven months to complete ?
50. A young woman, ret. 24, of strong build, when menstruation came
on, and that irregularly, at 22 years old, had been for two years chloro-
Ancient and Modern Theories. 377
tic, face pale and puffed, suffering from palpitations, asthma, heaviness
ot the legs, and constipation ; for four weeks she took a mixture of
Colocynth, Graswurzel, and quassia, for three weeks following malate
ot iron, and then antimony, after which the menses appeared and be-
came regular. What a wonderful demonstration, a splendid deductio
ad absurdum, of the mighty, not-sufficiently-to-be-estimated virtues of
Colocynth in chlorosis !
CHAPTER XL
Ancient and Modern Notions on the Nature and Essence
of the Active Principle of Colocynth.
The phantasies of the physicians of Arabia and the middle age3
taught that Colocynth was composed of fiery and calcined earthy parts,
and attributed to it a temperament heating and dry in the second or
third degree, and suitable only for cold and sluggish natures. Avi-
cenna gets in a terrible passion with the celebrated Alchindus, who
opposed the popular opinion, and ascribed a cold and moist tempera-
ment to the drug. Colocynth at that time thinned and dissolved the
thick, tough, glassy mucus of the bowels, dulcified the acidities of the
stomach, made patent the veins, shook the nerves, and unlocked the
noxious, corrupted humors from their most secret organic cubby-holes.
(Avicenna, Ettmuixer, and others.)
The iatro-chemical age next found in Colocynth a sharp, biting,
caustic salt, which irritated the sensitive and motor nervous fibres
{fibras nerveas sensibiles et motrices) of the intestinal mucous mem-
brane, and the excretory ducts connected with it, corroded the vascular
terminations, and decomposed the humors in a colliquative, feverish
fermentation. (Joan. Maur. Hoffmann, in Eph. Nat. Cur. Cent. X.
obs. 30.)
The moderns hold Colocynth to be a powerful irritant of the gangli-
onic system, especially of the pelvic cavity (?), and of the lower portion
of the digestive tube, particularly of the rectum ; that it excites the
functions of these organs, increases the secretions and excretions of the
intestinal canal, and of the kidneys ; by sympathy raises the activity
of the spinal marrow and its nervous connections ; and at times excites,
at others depresses, the functions of the brain. These opinions are
founded partly on physiological observations and experiments, but too
unsatisfactory and imperfect to afford a sufficient foundation for any
special indication for the use of Colocynth in disease, and are partly
set phrases, which you will find, with but slight variations, applied to
its immediate neighbors in the Materia Medica, and which give you
no insight whatever into any ground for selecting Colocynth in a given
case, in preference to scammony, hellebore, gamboge, or any other drastic
purgative.
378 .. Colocynthis.
Most pharmacologists of the present day, however, do not seem to
consider it worth while to seem to know anything specific about the
peculiar powers of Colocynth. They content themselves with setting
it down as " Purgans acre vehemens," or " Drasticum heroicum" and
with a few words refer to its former dangerous employment.* This
seems to us far better than beclouding and confusing the student
with a pretended knowledge, which, after all, is but empty fog.
Among our colleagues, Hausmajtn and Gerstel have ventured
theories of the action of Colocynth.
Hausmann 1 considers the essence of the action of Colocynth to be
excretory. The whole phenomena, composing both the morbific and
the curative process, are only preparatives to this end. On this ac-
count, it fixes itself more particularly in the large intestine, which is
especially an organ of excretion, and chiefly in the rectum, to the care
of which the immediate expulsion of the excreted matters is committed.
It is to be observed that the excretions, and of course the preliminaries,
are repeated at longer or shorter intervals, which indicates an affection,
not of a single tissue of the colon alone, but of the whole structure in
its muscular, cellular, and mucous tissues, and with its ganglionic nerves
and vessels. Since the separation of the excretions from the matters
which are to be retained in the organism is effected by means of the
bile, and the bile itself forms a part of the excreta, the biliary organ,
the liver, is necessarily affected. The most important excretory organ,
next to the rectum, the bladder, with its passages, is of course likewise
influenced. The brain is affected in consequence of its connection with
the liver. The muscular pains, which are the most prominent symp-
toms next to the colics, seem to be rather hard to reconcile with this
hypothesis; but if Liebig's theory of the metamorphosis of tissues and
animal motion be correct, that the muscles are undergoing a constant
change, corresponding in extent to the amount of force expended, by
absorption of the inhaled oxygen, and are therefore as constantly de-
manding an equivalent for the loss of substance, they are more easily
accounted for. For a substance which forces the bowel to an excre-
tion will carry along with it the whole contents of the canal, including
the undigested material for that very muscular supply, which is called
for by these uneasy muscular pains. According to this view, the con-
stant metamorphosis of the muscular substance is the grand original
cause and necessity of every excretion.
We have nothing less to urge in relation to this hypothesis, than
* Moll (Handb. der Pharmakoloyie, Wien, 1839) places Colocynth among
the "Drastica anti-dyscrasica," which, by their antagonistic action upon the
organism, produce such an irritation, especially of the vascular system con-
nected with assimilation, that an improvement is brought about in the con-
coction of the organic materials by a sort of metasyncrasis, of which the
diarrhoea is but a single symptom. (!) Old Patjlus ^Egineta was a deal nearer
the truth when he laid it down that Colocynth was less a sanguineous than a
nervous purgative, — a "Drasticum alteram," — and consequently a remedy
exerting a powerful influence over the nervous system, and capable of pro-
ducing alterations in its functional activity. — Watzke.
Ancient and Modem Theories. 379
that it applies with equal force to every purgative and laxative, and
gives us no^distinctive specific information in regard to Colocynth.
Gerstel's theory (which, with some modifications, we have no hes-
itation whatever in adopting)* is not put forward as a theory of the
nature and essence of the Colocynth-disease, hut as a conjecture con-
cerning its seat, the organs primarily and secondarily affected, and the
character, connection, and relations of the symptoms presented.
The physiological and clinical materials already accumulated, justify
the opinion that Colocynth exerts a direct specific influence on the
sensitive filaments of certain nervous centres and nervous tracts (espe-
cially of the celiac plexus and its ramifications, the fifth pair, and the
lumbar and femoral nerves), and that its action is confined to, or, at all
events, begins from the mucous and fibrous membranes, under the
influence of these nerves, and from the neurilemma of the nerves them-
selves.
This action results in the production of an abnormally exalted sen-
sibility, manifested by neuralgise and hyperaesthesiae, which, on the one
hand, give rise to congestion, hyperaemia, and, when repeatedly re-
newed with violence, even to inflammation, particularly in the brain
and the very vascular lining membrane of the small and laro-e intes-
tines ; and, on the other, though very rarely, may pass over into pare-
sis of the nerves themselves, especially of the sacral plexus, and the
sciatic nerves.
At the same time there appear symptoms of the diffusion of the
nervous influence, of reflex action and of sympathy, partly at the
proximal extremities of the affected nerves in the brain ; partly, though
more seldom, and apparently in consequence of the mediate connection
with the sympathetic by means of the plexus gastricus magnus, in the
peripheric ends of the vagus in the lungs and heart ; and partly in the
skin, which is directly or indirectly influenced by the affected nerves.
To the first cause we ascribe dulness, pressure, sensitiveness, painfulness,
and other symptoms of the head ; to the second, pressure, stitches in
the chest, constriction, asthma, palpitations, anxiety ; to the third, creep-
ing, twitching, sticking, drawing, <fcc., in the skin.
Besides this, the exalted sensibility (most in the mucous membranes,
* We must be permitted, however, to remark beforehand, that this theory
— if indeed it deserve the name — is by no means advanced as the best pos-
sible, and as putting a final bar to the zeal and energy of our colleagues.
"We only claim for ourselves, what we cheerfully grant to every one else, the
right of interpreting the phenomena caused by Colocynth in our own way;
if any one differ from us, we are content. In respect to theories, our toleration
knows no bounds ; since we know of none, not even our own, that is perfectly
satisfactory. If any one demand of our theory that it shall explain to him
the how, why, and wherefore of the action of the drug, we can only say that
that is beyond the limits of our wisdom. Why Colocynth attacks the nervous
system almost exclusively, and leaves the vascular unaffected ; why it attacks
the trigeminus, instead of the acusticus, or opticus, and why it seizes the sen-
sitive and not the motor divisions of it, we can as little say, as we can why
pumpkins bloom yellow instead of black or red. — Ed. Oest. Zeit.
380 Colocynthis.
but sometimes in the cellular tissue*) is accompanied by increased and
often perverted secretion, and imparts acridity to the secretions. Hence
burning and biting in the tongue, scraping in the throat, pyrosis, flatu-
lence, tenesmus, diarrhoea, frequent urination, lachrymation, catarrh, and
symptoms of a similar kind.
CHAPTEK XII.
Indications for Colocynth. — Allied Remedies. — Antidotes. —
Size and Repetition of the Dose.
The curative indications are essentially identical with the physio-
logical effects of a remedy. The latter once known, so are the former.
The study of the effects which Colocynth develops in the healthy
body, affords the best guide to its appropriate use at the bedside.
The usus in morbis can afford no fresh indications ;f — it merely sifts
and throws light on the materials furnished by pharmacology ; it de-
cides on the greater or less availableness, the value and meaning of the
medicinal symptoms, obtained by experiments on the healthy ; it is
the touchstone of the results of provings, confirming faithful observa-
tions, rejecting the product of inexact or superficial experiments, the
tissues woven by fancy or by falsehood.^ The clinical study, therefore,
of Colocynth, will have an important influence on its therapeutic em-
ployment ; it forms a necessary supplement to the curative indications
drawn from its physiological effects.
Let us first ylance at the indications for Colocynth furnished by our
colleagues.
With regard to the disposing causes of diseases which the medicine
is fitted to cure, according to Noack and Trinks, Colocynth corres-
ponds especially to sthenic, dry, bilious, melancholic, venous-hsemor-
rhoidal constitutions, and the cholerico-melancholic temperament. But
our experiments on the healthy as well as the published cures by Colo-
cynth, show it to have an absolute power over all constitutions and
temperaments. Dislike to speaking, irritability, moroseness, and other
symptoms, indicate, it is true, an influence, though perhaps not a direct
* See Weinke's proving, ante, p. 334.
f We are not at all disposed to throw stones at a Homceopath here and
there, who has become acquainted with, and continues to use, a remedy, such
as badiaga, filix-mas, &c, solely ex usu in morbis. We must make a virtue of
necessity. We must condemn, however, in the strongest terms, the conduct
of those who (like Hahnemann in his later editions) insert in the materia med-
ica all the symptoms of a disease which has been cured by a particular rem-
edy. This is opening doors and windows, and inviting error in ; this is a
process for converting a pure into an impure materia medica. Watzke.
\ We remind our readers of the pretended proving of medicines by Fickel,
the homoeopathic Judas. We know not that there can be found in the whole
range of homoeopathic literature more than two cures effected by Fickel'»
lying drug*. — Watxke.
Therapeutic Indications for Colocynth. 381
one, on the mind and temperament ; but they appear as the usual
accompaniments of abdominal sufferings, from whatever cause they
may have arisen. At all events, a great number of medicines have
this in common Avith Colocynth.
The opinion expressed by Hahnemann with regard to the curative
indications to be drawn from exciting causes, that Colocynth was es-
pecially adapted for the effects of anger, indignation, vexation, and
brooding over the unjust treatment of oneself or others, among which
he enumerates cramp in the calves of the legs, spasmodic colic, sleep-
lessness, rheumatism in the limbs, &c, we believe to be so far well-
grounded that the passions sometimes, especially if acting for a length
of time, give rise to morbid phenomena similar to those which Colocynth
produces in the healthy ; but it is not on this account proved that Colo-
cynth has any direct specific effect on the mind. Neither have our
experiments shown any aggravation of the symptoms enumerated to
arise from mental impressions, nor have we found in our clinical obser-
vations a sufficient number of cases in which Colocynth cured the
symptoms mentioned by Hahnemann more surely and quickly
when they proceeded from mental than when they were due to physi-
cal causes.
On what grounds Franz proceeds, when he affirms that Colocynth
takes precedence even of chamomile, for anger and its effects, we can-
not tell. There is more foundation for his opinion that it is peculiarly
adapted for women with abundant catamenia. The power Colocynth
possesses to promote the flow of the menses, and to bring on menorrha-
gia, and even abortion, is proved beyond all doubt.
If Colocynth is more often useful to persons who lead a sedentary
life than to others, this is not to be ascribed to any especial susceptibility
of such persons to the curative action of Colocynth ; it only shows that
neglect of exercise is not unfrequently the cause of diseases for which
the remedy is found in Colocynth.
Homoeopathic indications for Colocynth, drawn from the symptoms
of the diseases it has cured, such as rheumatismus acutus, gouty
conditions, paralyses, neuralgias, migraine, gastralgia, ischias, psoitis,
sporadic cholera, epidemic dysentery, &c, are the counterparts of those
which the Arabians set up for it. The reformed science of healing
ought to reject every such indication.*
Among Hahnemann's therapeutic hints before the third edition of
Colocynth, we find among several unimportant symptoms, such as
anxiety, toothache, rumbling in the abdomen, the following : " Defi-
ciency of religious feeling, eczema of the face, and inguinal hernia."
•
* It seems very probable that the (generally unjust) condemnation pro-
nounced by Hahnemann upon all nosological names, was founded upon no
other ground than a conviction of the utter worthlessness of such names in
reference to therapeutic indications. Unfortunately, he fell out with himself
a little subsequently. The scheme of diseases, with which he introduced his
antipsoric remedies, is but little better than the indefinite, indistinct, gener-
alizing indication* of the old school. — Watzke.
382 Colocynthis.
Neither our somewhat thorough proving, nor yet Hahnemann's, has
given any sanction to the charge of impiety against Colocynth, and we
greatly fear that Hahnemann has introduced that symptom from some
one of his patients. As to the facial eruption and inguinal hernia, our
homoeopathic literature presents but a single feeble analogy.*
Hahnemann mentions, as a leading characteristic of Colocynth, its
power " to excite cramp-pain, i. e. (!) tonic cramp, with constrictive
pressive pain in internal and external parts." This definition is ob-
jectionable, inasmuch as a theory of the cause of the pain is implied ;
and is also defective, for Colocynth evidently produces its direct and
primary abnormal impression on the sensorial sphere of the nervous
system. f The influence it exerts over the motor sphere is almost lim-
ited to the involuntary muscles ; and in this case also is indirect, and
to be ascribed to sympathy.
Meliciier's puerperal fever, and Ruckert's ])soitis chronica, we have
already dissected in Chapter X. They are both to be stricken out of
our repertories, and lumbago substituted for the latter. Whether the
diagnostic criticisms which we have made in reference to Schuler's
ophthalmia arthritica, Ruoff's peritonitis, Schron's sporadic cholera
and vesical catarrhs, Schellhammer's dropsy of the chest and abdo-
men, and Gross's stiff arm, are deserving of regard in anv future
development of the curative indications of Colocynth, is left to the
judgment of our colleagues.
The hypothesis of Schron and Hering, that Colocynth is indicated
for ichthy. sis and lepra, rests chiefly on phenomena of doubtful value,
which occurred in two patients cured by Colocynth.J
Noack and Trinks' indication's for Colocynth are chiefly abridged
histories of face-aches, megrims, colics, and diarrhoea, treated exclusive-
ly by Colocynth, by Gaspari, Attomtr, Schuler, Nenning, Hart-
mann, and others. Having given these cases in full in our 10th chap-
ter, we have nothing farther to say of them here. We shall only quote
some remarks derived from the posthumous papers of Dr. Hartlaub
senior. According to these observations, apparently made upon the
sick, the following symptoms are indications for the employment of
Colocynth :
* Nenning (Allg. horn. Zeit. vii. 73) mentions a single case in which Colo-
cynth alleviated the pains of an epiplocele. — Watzke.
f Thus Colocynth affects only the sensitive filaments of the fifth pair (of
the first division, especially the frontal branch, the whole of the second di-
vision, and the lingual and auricular of the third), -while its motor portion
which does not run through the ganglion, and is merely destined for the mus-
cles of mastication, is not in the least affected by it. Watzke.
% Hering (Archiv, xi., 2, 36) proceeds on the following symptoms of Colo-
cynth :— Shortening of the tendons (?) ; drawing up of the limbs to the body •
tractive pain in the tendons of the thumbs; cramp-like pain in the hands'
making it difficult to unfold them; pain as from the psoas bein» too short-
tearing in the soles ; pain from the side of the nose up to its root* a precur-
sory symptom of ulcers in the nose (?); scaling off of the skin of the whole
body (?) ; itching in the ham ; buboes in the axilla; (?). — Watzke.
Therapeutic Indications for Colocynth. 383
1. Intense pain in the forehead (especially in the eyebrows) and in
the face (especially pulsation and tearing in "the cheek-bone) beginning
"with itching; worst in the evening and night; inflammation of the eyes,
on looking at the sky ; pain as if the eyes would fall out of the head.
2. Tearing pain, going from the pit of the stomach deep into the
abdomen as though the chest would fall, aggravated by coughing and
walking ; pain in the small of the back ; tenderness of the abdomen to
the touch ; alternation of cold and heat ; on going to stool, violent pain
from the abdomen to the small of the back.
3. Spasmodic, inflammatory, and flatulent colic ; colic from cold and
mental emotions; every evening at six o'clock a single vomiting of bitter
matter, preceded by cutting pain in the left hypochondrium. drawing to
the abdomen, stomach, and back ; anorexia, hard fasces.
4. Diarrhoea, with pressure on the abdomen and tenesmus.
5. Sticking pain, sometimes in one place, sometimes in another, in one
of the lower limbs, causing limping.
Finally we introduce the diffuse indications laid down by Heciien-
berger, which are derived less from provings on the healthy than from
experiments on the sick, and prove abundantly that he scarce dimly ap-
preciated the character of Colocynth, much less defined it in a clear light.
It is indicated, according to him, first in affections appealing in winter
or spring as a result of a torpid, necessitous, confined life as a status
pituitosus, gastrismus chronicus, febris gastrico-pituitosa, gastrico-
rheumatica, atrabilaria et venosa Hichteri, or as the hepatic congestion
and portal obstruction of the old diagnostics, or as ptyalismus suecicus,
and presenting the following symptoms :
Peculiar, vertiginous, dull headache, especially in the morning after a
restless, dreamy sleep; earthy, puffed face; yellowish conjunctiva; nau-
seous taste ; smell from the mouth ; tongue, white coated ; inclination to
vomit in the morning after rising ; loss of appetite ; distressing fullness of
the epigastric region ; frequent pyrosis with boring, constrictive pains in
the stomach ; vomiting of the ingesta with a feeling as if the stomach
were floated with water, at first periodical, finally more constant; flatu-
lence ; dull, deep-seated pain in the hepatic region; irregularity of the
bowels; expectoration of mucus, with rattling and oppressed breathing;
frequent chills ; heaviness of the feet, with wandering pains in the limbs ;
general debility ; emaciation ; irritability ; melancholy frame of mind ;
thoughtlessness ; torpidity of all the intellectual faculties.
Hechenber<»er considers Colocynth indicated in the second place, in
disorders which come on secondarily to previous diseases, in consequence
of neglect, frequent exposure to cold, &c. — atonic dropsy, brcmatemesis,
haeraorrhoidal colic, raenostasia, or which appear as metaschematic or
crises erroneoz, such as ischialgia, jaundice, gout, hemicraniae.
Were we required to give an exact and complete view of the indications
for Colocynth, we should refer the inquirer to the pharmacological and
clinical materials already given, (chapters iv.-ix.) Any abstract of those
materials would be defective, and could not save the student the trouble
of studying those chapters. Besides this, a theory of the indications
BB
384 Colocynthis.
cannot be derived from a simple abbreviation ; it requires abstraction — a
disposing of the facts according to some theoretical view. From its very
nature it can be nothing more than the glass through which we view the
phenomena. In presenting below to our colleagues, therefore, our gene-
ralization from the preceding chapters, we do not imagine ourselves to
have found medical treasures which they would not have discovered by
their own efforts ; no, we merely use our right to see things through our
own glass, and are neither weak enough to believe it is the best, nor so
deficient in modesty as to insist upon its adoption by others.
The great, clumsy, misshapen monster presented by the indications for
Colocynth of the old school, embracing almost all the diseases to which
the human frame is subject, (need we refer to our second chapter ?) is
reduced by the physiological provings, and the critical sifting of the
clinical materials before us, to a less pretending, but we trust a well-
formed, tolerably healthy, and very promising offspring. Colocynth has,
in our hands, instead of a neglected and despised polychrest, become an
indispensable oligochrest. Its formerly much-lauded powers against
dropsies, epilepsies, apoplexies, paralyses, intermittent fevers, chlorosis,
and jaundice have proved either illusory, or at least problematical.*
The whole curative sphere of Colocynth in the new system, is almost
confined to a few neuralgise and hypersesthesise, and of these almost ex-
clusively those which affect the trigeminus, the coeliac plexus, and the
lumbar and femoral nerves. And even here its efficacy is limited to a
few forms of hemicrania, prosopalgia, coelialgia, colic, and ischialgia, de-
pending on peculiar conditions, and appearing under peculiar circum-
stances. What these are, will best appear from a careful perusal of
chapter viii. ; we venture, however, on some conjectural hints.
1. The hemicraniai and prosopalgia; which Colocynth cures, proceed
from an exaltation of sensibility, from an excitement dependent on rheu-
matic, gouty, or gastric irritation, or on congestion of the fifth pair, in
all cases on a purely functional derangement of the sensitive filaments.f
In organic changes from deeper causes, the efficacy of Colocynth is very
doubtful.
Hemicranioe, arising from thickening of the arachnoid, or hypertrophy
of the meninges, tumefaction, and induration of the pacchionian bodies,
in erosion or exostosis of the bones of the skull, effusion of serum, or
purulent deposits in the brain, will receive no benefit from Colocynth.
* If we did not confine ourselves in establishing our curative indications to
physiological and clinical observations, but allowed some play to theory and
hypothesis, we should incline to argue favorably of the effects of Colocynth in
intermittent fever, regarded by many authors as a pure neurosis of the cceliac
plexus ; in epilepsy, depending on spinal irritation ; in dropsy, where the ac-
cumulation is owing to exaggerated nervous influence ; and in apoplexy, brought
on by neurosis of the ganglionic system, with a reflex action on the brain.
f By this we do not by any means intend to deny to Colocynth all efficacy iu
complaints in which organic changes have taken place, and plastic effusions have
been formed. The latter are frequently consequent on abnormal nervous in-
fluence, and disappear with it. — Watzke.
Therapeutic Indications for Colocynth. 385
Recourse may be had in such cases for cure or alleviation to calc, caust,
sep., sil., sulph., and graph.
In like manner, Colocynth is of no use in organic and centric proso-
palgia, from exostosis of the teeth, hypertrophy of the bones of the
skull or face, fungous and scirrhous tumors of the membranes of the
meninges, cartilaginous or aneurismal malformation of the cerebral
veins, &c. More may be effected in such cases by ars., aur., magnes.,
mice., and sep.
The Colocynth-hemicraniae are generally seated in the course of the
frontal nerve, and are accompanied by violent pains in the eye, and al-
ternate with neuralgias of the cceliac plexus. Next in efficacy to it are
bry. and nux-vom., and next to them puis., bell., phospk, valer., ckam.,
agar., verat.
In the prosopalgia? to which Golocynth is suited, there are no twitch-
ings of single muscles of the face and palsied feeling of the affected side.
The pains follow the course of the infraorbital nerve, are frequently
periodical, and are accompanied by toothache, {neuralgia infraorbito-
dentalis.) Next to Colocynth stand in this connection, bell., caps., and
verbasc; and, more remote, china, staph., con., nux-vom.
2. The neuralgia; of the coeliac plexus and its branches, are particu-
larly likely to be quickly and permanently removed by Colocynth, when
they occur as substantive affections, not caused by derangement of
stomach, but by cold, vexation, or anger, occurring during the period of
evolution, complicated with spinal irritation and neuralgia of the femoral
nerves, with haemorrhoidal difficulties, chronic diarrhoea, or vermicular
symptoms.* Next in efficacy come cham., bell., puis.; then valer.,
cocc, coff., nux., secale, ign., stann.
Colocynth will hardly relieve, far less cure colic from inflammation of
the great gut or peritoneum from gall-stones or nephritic calculi, per-
forating ulcers in the stomach, mesenteric tubercles, tubercular ulcers
in the intestines, &c. Some of these set all treatment at defiance ; others
require merc.-viv., or corr., bell., bry., canth., and ars.
3. Of the ischialgia those most under the control of Colocynth, are
such as are caused by affection of the terminating filaments of the spinal
cord, as also those arising from cold, from violent emotions, or remaining
after mechanical violence, or connected with gout, suppressed haemor-
rhoids, or the processes of involution and evolution, or complicated with
* Colocynth is suited in an especial manner to the affection, first described by
Romberg, (Lehrbuch der Nervenkranheiten, 140,) under the title of "neuralgia
hypogastrica." It is a hyperesthesia of the hypogastric plexus. The symptoms
are, — pains, as of labor, in the lower belly ; pressive pain about the sacrum,
with sensation of pressure on the rectum and bladder, and in women on the
uterus and vagina. Pains in the upper part of the thighs are a frequent con-
comitant. In girls, in whom it not unfrequently occurs at each menstrual period:
during the development of puberty, the symptoms resemble greatly those of
prolapsus or retroversion of the uterus, but come on in paroxysms, and are not
relieved by change of posture. This affection occurring in the male sex commonly
passes under the name of hemorrhoidal colic. — Watzke.
386 Colocynthis.
affections of various parts of the cceliac plexus. Cham., rkus, puis, are
cognate remedies.
It is of no value in ischialgiae, from tumefaction of the bones of the
pelvis, carcinoma of the pelvic viscera, change in the substance of the
nerves, or morbus coxarius, or in those which are due to the localization
of a morbid condition diffused through the system. Recourse must be
had in such cases to remedies that are homoeopathic to the fundamental
evil, such as calc, sil, carb.-veg., mere, ars., hep.-sulph., sulph., and
others.
In the morbus-coxarius itself, Colocynth will be found of little service,
and Stapf is greatly mistaken in his surmise, (Archiv., xvi. 1, 93,) that
it will be found one of the chief remedies in spontaneous (nervous)
lameness. Both the cases which Thorer and Lobethal (vide chap-
ter x) think they cured with Colocynth seem to us to have been cases of
ischias. The changes in the position of the foot and trochanter are
quite as remarkable in that disease. (Compare Canst att Med. Klin.,
3, 30.) No remedies but such as we have mentioned above will suffice
to arrest the progress of a specific inflammation of the hip-joint.
Belated and Antidotal Remedies. — The affinities and antidotal rela-
tions of Colocynth, and vice versa, may be gathered from the foregoing
•observations.
Where the formidable symptoms of poisoning by Colocynth make
their appearance, the mechanical and chemical resources of medicine
must be resorted to, as in other cases of poisoning. In addition to
copious draughts of oil, warm milk, or water, wet bandages applied to
the abdomen, and the administration of tincture of opium and bhek
coffee, effect the most speedy relief.
We do not know on which grounds Jahr asserts Colocynth to be
merely the antidote of causticum ; and Noack and Trinks, that it coun-
teracts only causticum and mercurius.
Duration of Action. — The average duration of the action of Colocynth
may be set down at from 2 to 6 hours ; but when it has produced an
intense effect, it frequently extends over several weeks.
Dose and Repetition. — No fixed rules can be laid down as to the size
and repetition of the dose. Judging from our own experiments, and
the published cases of cure by Colocynth, we are inclined to think, that
the sixth (decimal) dilution or trituration is seldom too large, and the
first as seldom too small a dose.
We are in the habit of repeating the dose of Colocynth every hour,
or every 2, 3, or 4 hours in acute, and in as many days in chronic cases!
Coccus- Cacti. ^87
14. — COCCUS-CACTI.
Coccus. — Coccus indicus, Coccus Araericanus, Grana fici indici, Cochi-
neal, Coccinella or Coccionella, Cochenilla, Cotonella, Conzenilla, Coche-
nille, Scharlachwurm.
1. Description and Preparation.
This hemipterous insect is extensively raised in Mexico for the pur-
poses of commerce. It was employed by the natives, long before the dis-
covery of America, as a means of obtaining an ornamental dye, and it is
for this purpose that it is now largely imported from that country. Large
plantations of Cactus are there cultivated, upon which the animals are
placed, and suffered to grow and propagate, from which three harvests a
year are gathered.
The female is the only valuable animal. It has a convex body, flat-
tened below, nearly twice as large as that of the male; apterous, bluish
red, covered with a white farina ; antennae short, eleven-jointed, filiform,
and setaceous ; feet short. When dried, they are one or two lines long,
wrinkled, of an irregular figure, convex on one side, and flat, or some-
what hollow on the other. They are inodorous, have a bitterish, warm
taste, tinge the saliva violet-red, and yield a dark-red product. Three
varieties are distinguished in commerce, the differences in which are said
to be due to differences in the method of curing the insect.
1. Coccus renigrida. — Killed in boiling water, of a fine uniform red-
dish or purplish-black, and destitute of the silvery wool.
2. Coccus jaspeada. — Killed in ovens, of a purplish gray, and covered
with a silvery powder, appearing under the microscope like fine wool.
3. Coccus sylvestris, (Granilla.) — Consisting of the sifted powder and
fragments of the insect.
The second variety is the most esteemed for coloring purposes ; the
whitish powder indicating the female : the appearance has been simulated
by rolling the other varieties in baryta or talc, a deception at once de-
tected by the microscope.
The first variety is the one used in the provings, as being least likely
to be adulterated.
Pelletier and Caventou found the constituents of cochineal to be car-
mine, (the coloring principle,) peculiar animal matter, fatty matter, (com-
posed of stearin, olein, and an odorous acid) and phosphate and carbo-
nate of lime, chloride of potassium, phosphate of potash, and a salt of
potash, containing an organic acid.
Preparation. — After being well washed in warm water, and dried, the
cochineal is pulverized and macerated in ten times its weight of alcohol,
for a fortnight, when the mother tincture is obtained by filtration.
Or, the powder may be triturated in the usual way with sugar of milk.
388 Coccus- Cacti.
2. Digest of the Symptoms.
We owe our knowledge of this remedy to the Austrian Society of
Provers, in whose Journal the experiments were first published, (Band
iv. S. 509,) and where may be found the following
AUTHORITIES.
1. Caspab, 509. 9. J. G. M., 545. 17. Wurmb, 579.
2. A. F., 511. 10. Marenzeixer, 548. 18. Zlatarovich, 582.
3. Frohlich, 512. 11. Muller, 559. 19. Rudolph, 588.
4. Mad. Kummer, 516. 12. Schweikhofer, 562. 20. Eduard, 588.
5. Gottwald, 518. 13. Mad. Schweikhofer, 566. 21. Franz, 589.
6. HuBfcR, 523. 14. Rudiger, 567. 22. M. H., 589.
7. Huber, 530. 15. Wachtel, 568. 23. Adolphe, 589.
8. Lach, 540. 16. Mdlle. Therese, 574. 24. Reil, Viertelj. i 194.
Jg^" The figures refer to the authorities; curative symptoms are preceded
by a cypher, (0).
MENTAL AND MORAL.— Exciting. 1. Gay mood, (13.) Very
gay mood, quite unnatural, (4.) Very great flow of spirits, notwith-
standing he had been peevish and irritable the evening before ; even the
headache and sensation of fullness, which come on in the evening, do not
affect his spirits, (11.) An unusual gay mood takes the place of his ill-
humor in the evening, (5.) 5. Loquacity, (3.) Depressing - . Ill-
humor, without any reason, during the whole day, (5, 12.) Sadness
during the whole day, unattended by any physical suffering, (16.) She
is very low spirited, and wearied with the pains in the genitals, (16.)
Sombre mood, (9.) 10. Indifferent mood in the afternoon; indisposition
to labor, but not from ill-humor ; he is rather fatigued, overcome, (8.)
Great indisposition to labor ; ill-humor, and great moral irritability, (8.)
He wakes at 6, A.M., physically well, but morally indisposed, and very
irritable, (8.) Great moral irritability, (13.) Anxiety in the evening, (5.)
HEAD. — Headache in general. 15. General dull headache,
aggravated by shaking bis head, during the whole morning, (7.) Con-
gestion of blood to the head ; on entering a warm room, he was obliged
to go out again, which made him feel better; this occurred three times
before noon, (7.) Congestion of blood to the head, with pressive pain in
the orbital region, and sensation of inflation of the stomach, soon after the
dose, (15.) Painful lancinations through the brain ; they last for an hour,
and are accompanied by an obstruction of the meatus auditorius, (18.)
Confused head, (5, 7, 10, 14.) 20. Confused head, with general de-
pression, (6.) Confusion of the head, which disappears in the open air,
(10.) Confusion of the head during the whole day, (3.) Confusion
in the morning on waking, as though from a drinking debauch ; tongue
white, and pasty taste, (7.) Confusion of the head in the morning, with
feeling as if the temples were too narrow, (9.) 25. Confusion of the
head after breakfast, (5.) Confusion of the head, redness of the face and
hand*, with swelling of the veins, and throbbings in all the arteries, after
-dinner, (11.) Confusion of the head in the evening, (5.) Confusion of
Coccus- Cacti. 389
the head in the evening as if intoxicated, (7.) Confusion of the head on
entering a warm room ; towards evening it becomes a moderate head-
ache, which disappears in the open air, (3.) 30. Great dullness of the head
in the evening, with aching in the vertex, and burning in the skin of the
forehead, (18.) Transitory stupefaction, (5.) Stupefaction on waking
in the morning, like the effects of drink, (7.) Feeling of fullness in the
whole head, (4.) Sensation of swelling of the whole head, accompanied
by anxiety, in the evening, (5.) 35. Pressive aching in the brain, par-
ticularly in the region of the root of the nose, accompanied by pressure
on the internal canthus ; it lasts ten minutes, (7.) Pressive headache,
like that of indigestion, with general coldness, especially in the back, and
eructations of wind, (10.) Pressive headache in the morning on waking,
as if after excessive drinking, which disappears after having left the bed,
(7.) Pressive headache at breakfast, (8.) Pressive headache in the
evening, but slight, (16.) 40. Head feels empty during the day, (5.)
Beer gives him the headache in the evening, although he is used to it,
(7.) Frontal. Dull and digging frontal headache in the evening;
it lasts the whole of the next day, (2.) Heat in the forehead, (15.)
Confusion in the frontal region, with feeling of weight on waking, (9.)
45. Dull, pressive, frontal headache ; the rest of the head is only con-
fused, (4.) Pressive ache in the region of the superciliary arch, dry-
ness of the nasal mucous membrane and of the pharynx ; he cannot de-
tach the mucus either by spitting or blowing ; increase of the lachrymal
secretion, particularly copious in the open air ; the tears seem thicker
than usual, (15.) Two little pimples on the right side of the forehead,
(9.) Violent lancination in the head, to the right of the coronal suture,
in the afternoon, (1 8.) Frontal headache in the left frontal eminence ;
it leaves there to occupy the parietal and temporal regions, extends to
the zygoma, and causes in all these parts a dull, rheumatic, and cutting
aching, (11.) ■ 50. Pressive aching in the left frontal region, which some-
times extends into the occiput, (2.) Frontal headache, increased by
moving or turning the head, and even when using the arms, (7.)
Parietal. Dull, digging pain toward the posterior edge of the right
parietal bone, coming on in paroxysms, like waves, in the morning in
bed, (6.) Vertex. Heat in the vertex, (7.) Confusion of the head in
the vertex, (12.) 55. Dullness of the head, especially in the vertex, (12.)
Great dullness of the head, particularly in the vertex, in the evening when
walking, (12.) He wakes with a pressive, burning pain in the vertex,
which lasts for an hour, but goes off as he has gone to sleep again for a
little while, (18.) Temporal. Lancinating pain in the temples in the
morning, (4.) Pressure in both temples, (5.) 60. Violent throbbing,
pressive pain in both temples at 1 P.M. ; it lasts an hour, frequently al-
ternating with heat and redness of the face, and unaffected by either mo-
tion or rest, (15.) Weak pressure, extending from the temples to the
vertex, and disappearing after bathing the parts in cold water, (8.) Draw-
ing and pressure in the temples, (1.) Pressive pain in the right tempo-
ral region, (1.) Dull, lancinating pain in the left temple, disappearing
on external pressure, and returning when the pressure is removed, (12.)
390 t Coccus- Cacti.
■Vlastoidean region. 65. Pressive pain in the right temporal region
soon after rising, extending sometimes into the left ear, and lasting all
day, (17.) Bruised pain around the left external ear, extending along
the left side of the neck to the left clavicular and thoracic region, (6.)
Violent pressive and throbbing pain in the left mastoid process, in the
heat of the bed before midnight, increasing and becoming boring from
within outwards, (6.) Pressive and tensive pain in the temporal bone,
but particularly in the mastoid process, (6.) Pressive and lancinating
pain in the bones, in the neighborhood of the left ear, in the evening in
bed ; the pain becomes digging and congestive, has very short remis-
sions, and extends, when most severe, into the cervical and clavicular re-
gion, the left inferior molars, and the left occipital region ; it is accom-
panied by lancinations in the left tragus, and a disagreeable roaring in
the left ear, (6.) Occipital. 70. Dull, digging pain in the left side
of the occiput in the evening, extending toward the ear, (6.) Feeling of
coldness in the occiput, as though a cold breeze were blowing upon it,
(5.) Feeling as if the occiput, from one mastoid process to the other, were
encircled by a burning band, at the same time great moral distress ; by
degrees the whole scalp became involved, and seemed to him to contract
and shorten ; formication at the roots of the hairs, which stood on end,
(11.) Drawing and slight pressure in the occiput, temples, and right
eye, (1.) Feeling of pressure and heat in the occiput in the evening,
(7.) 75. Pressive pain in the occiput, accompanied by a feeling of swell-
ing in the scalp ; this feeling extends to the left cheek and nasal surface,
(1.) Scalp. Itching in several places on the scalp in the afternoon, (6.)
Lancination, causing him to scratch the scalp at midnight on waking, (6.)
Painful elevation on the vertex, of the size of a lentil ; it disappeared in
the evening, but the place was still sore to the touch, (18.) Formication
in the scalp, forcing him to scratch, and followed by a disagreeable sen-
sation in the morning on waking, (8.) 80. Feeling as if the scalp were
too tight upon the cranium, with formication at the roots of the hair, (11.)
Sensitiveness of the scalp on the vertex, (18.)
EYES. — Trembling of the left lower lid, (6.) Feeling as if a hair had
got between the eye and the lid in the morning on waking, forcing him
to rub, and followed by a forcing pain in the interior of the left eye, (6.)
Feeling as if a foreign body were placed between the eye and the lid, in
the evening, (17.) Feeling as if the edges of the lids were swollen, (17.)
Slight agglutination of the lids in the morning, (18.) Burning of the
lids and of the skin of the right leg, (18.) Slight smarting of the edges
of the lids, (18.) Drawing and pressure in the right eye, (1.) 90. Rheu-
matic pain, extending from the eye into the forehead, in the evening, (7.)
Violent throbbing pain, extending from the eye into the squamous por-
tion of the temporal bone and its internal surface, and then into the occi-
put, lasting more than a quarter of an hour; it feels to him as though a
liquid were injected into a diminutive vessel by successive strokes of a
piston, (6.) The right conjunctiva very, much inflamed, (9.) The inflam-
mation of the conjunctiva returns the next day more violently, (9.) The
Coccus- Cacti. 391
conjunctival inflammation diminishes on the third day, (9.) 95. Sight
weaker than usual, (9.)
EARS. — Rheumatic drawing above and behind the left ear, followed by
roaring which lasts a long while, in bed, before midnight, (6.) Pressive
and tensive pain in the left mastoid process and clavicular region, accom-
panied by continual roaring in the left ear, (6.) Drawing pain in the
convex part of the concha, aggravated by touch, (6.) Violent itching in
the right concha and external meatus, (6.) 100. Lancinations and vio-
lent itching in the right tragus, (6.) Itching pruritus, sometimes in the
right, sometimes in the left tragus, (6). Itching lancination in the exter-
nal meatus and right temporal region, (6.) Tickling and itching in the
left meatus, frequently repeated in the evening, afterward accompanied
by pressure in the concha, (15.) Frequent itching in the left external
meatus in the morning in bed. 105. Itching in the right external
meatus, inducing him to introduce his finger; it frequently changes to
lancination, is accompanied by roaring in the left ear and stinging lancina-
tions in various parts of the skin, even of the prepuce, (6.) Itching and
voluptuous titillation in both ears, which seems to extend from the ex-
ternal meatus through the internal ear into the mouth, and only lasting
fifteen or twenty seconds, (6.) Intolerable itching in the external meatus
in the evening in bed, which can only be quieted by introducing the
finger, (6.) Drawing in the right meatus lasting all the evening, (17.)
Violent lancination in the interior of the right ear, followed by a dull
pain in one of the superior posterior molars, (6.) 110. Violent lancina-
tions in the left ear, (5.) Frequent itching in the left ear, (6.) Drawing
pain in the interior of the ear, (6.) Cramp-like, drawing pain in the
interior of the right ear, (6.) Drawing from time to time in the left ear,
(17.) 115. Simmering, as if from boiling water, in the interior of the
left ear, (6.) Roaring in the ears, like a tempest among the trees, in the
evening in bed, (6.) Itching and noise in the left ear, in the evening, (6.)
Heat and tinkling in the ear, (6.) Crepitation in the left ear during de-
glutition, (6.) 120. Sharp tinkling in the interior of the left ear, (6.)
Painful throbbings in the interior of the left ear, isochronous with the
beats of the heart, (6.) Feeling as if the ear were stopped with cracking
in the interior, (9.) Feeling as if the ear were stopped, not interfering
with the hearing, and accompanied by a tensive and pressive pain in the
left mastoid process, extending into the left side of the neck into the cla-
vicular region and the last inferior molar teeth, (6.) Hardness of hearing,
as if the ears were stuffed with cotton, (5.) 125. Both ears feel
stopped up for a quarter of an hour in the evening, with feeling of
pressure and forcing in the meatus, (15). The pain in the ear when at
its height extends into the interior of the ear, the left occipital region, the
posterior inferior molars, and along the sterno-mastoid into the clavicular
sternal region, (6.) The pain in the ear is accompanied by a sensation as
though liquid cerumen were about to run out, (6.) The pains in the ear
are aggravated when lying on the left ear, and last, with little cessation,
during the whole day, (6). The pains which extend into the neighboring
part, after the severe aching in the ear, produce a sensation of swelling
392- Coccus- Cacti.
there, (6.) 130. The itching in the ear appears especially when he
enters a warm room from the open air, (6.)
NOSE. — Sensation of a pressive pain at the root of the nose and in
the frontal eminences, (9.) Two little pustules, of the size of a millet-
seed, on the left ala, (15.) Redness and excoriated feeling in the opening
of the nostrils, (4.) Yellow pulverulent matter at the internal edge of
the nostrils, (18.) 135. Crusts in the opening of the nostrils, (5.) Dry
nasal crust, nose obstructed, stopped, (1.) He is obliged, during the day,
to snuff up cold water in consequence of the dryness of the nostrils in
order to ease the sensation ; he is finally enabled to detach, by blowing,
a piece of dry mucus, which relieves him for a time, (9.) Feeling of ob-
struction in the nasal cavity with aqueous secretion, (4.) Much mucus
runs from both nostrils without any other catarrhal symptoms, (10, 18.^
140. Secretion of a very fluid nasal mucus during the day, (5, 9.)
Slight coryza during the evening, with lancinating pain in both temples
and excoriated feeling in the throat, (4.) Nasal and laryngeal catarrh,
aggravated in the morning, (5.) Frequent and violent sneezing in
the morning, (10.) The attacks of sneezing return the next day at
the same hour, but the burning at the edges of the nostrils is continu-
ous, (11.). 145. Very violent sneezing in the afternoon without appar-
ent cause, in several paroxysms, in consequence of which the edges of
the nostrils and the furrows of the alse burn as if from pepper, (11.)
Violent sneezing, leaving a sense of roughness in the throat as if from
eating high-seasoned food, (15.) Frequent sneezing, accompanied by a
dry cough, (5.) Frequent sneezing in the evening, (17.) Itching in the
nostrils, followed by repeated, prolonged, and very violent sneezings, (12.)
150. Frequent sneezings, (5, 18.) Feeling of dryness at the posterior
opening of the nares, (6.)
FACE. — Heat of the face in a room without a fire in the morning on
waking, (3.) Violent heat in the cheeks for half an hour, (3.) Pecu-
liar pricking heat in the cheeks without redness, (11.) 155. Isolated lan-
cinations, violent and deep, between the tragus and the zygomatic process,
(6.) Formication and drawing in the left half of the face and nose,
analogous to a prosopalgia having its seat in theses anserina, (suborbital
branch,) (11.) Feeling of formication in both zygomatic processes, (15.)
Formication beginning over the left cheek-bone, extending above the
bridge of the nose on the left cheek, and recurring three times on the
same day, (15.) Sensation of fullness in the superior maxilla, as if the
teeth were about to be forced or pushed out of their sockets, (2.) 160.
Pain in the temporo-maxillary articulation when chewing, with crepitation
in the joint when swallowing, (6.) Pain in the right parotid region, fol-
lowed by pain in the right sublingual gland, with increased secretion of
saliva, (6.)
MOUTH. — .Lips. Little furrows (not cracks) in the lips, which look
as if sprinkled with flour, (15.) Oblong, reddish-blue spot on the upper
lip, disappearing after twenty-four hours, (15.) Slight sensation of con-
traction of the skin of the upper lip. Teeth. 165. Lancinating itching
in the gum of the right superior incisor, in the morning in bed, (6.)
Coccus- Cacti. 393
Excoriated pain in tbe inferior alveoli, which have lost their teeth, (15.)
He is waked by an excoriating sore pain in the teeth and left upper and
lower gums, with great sensibility to the touch; but no sooner had he
changed his position, (he was lying on the left side,) than the pain dis-
appeared ; he slept quietly until 5 a.m., when he felt an irresistible desire
to make water, (10.) Sudden drawing in the incisors and in the right
auditory meatus, in the forenoon, (17.) Sudden drawing in the right
inferior incisors, and pressure in the left globe, in the forenoon, (17.)
170. Feeling in a lateral inferior incisor, as if it were seized with cold
fingers and drawn up, in the evening, (15.) Odontalgia in paroxysms,
in the morning on waking, especially in the incisors and left eye-tooth,
with a sensation as if a cold wind were blowing upon it, (7.) The pains
in the incisors and upper eye-tooth are aggravated by inspiring cold air
and in closing them upon the stem of the pipe, (7.) Dull pain in the
last inferior molar, (6.) Drawing in the right molars, at noon, (17.)
175. Dull, slightly digging pain in the right superior molars, in the
morning on waking, accompanied by dull headache over the right eye,
(6.) Aching in a carious thircT upper molar, at 6 p.m. Very violent
toothache in a carious tooth, (1.) The pain in the third upper molar is
aggravated by the touch, and is not eased by cold water, nor by heat, (8.)
He resorts to extraction of the third superior molar, (carious,) but the
pain continues in the alveolus through the whole day, (8.) 180. Sudden
drawing in the teeth and itching on the left arm, (17.) Drawing in the
teeth of the left side during the whole day, (17.) Teeth painful when
closing them against each other, (7.) Teeth exceedingly sensitive to cold,
(11.) Sensitiveness of the teeth to cold air, (17.) 185. Great sensi-
tiveness to the cold water when cleansing the teeth in the morning, (17.)
Painful sensibility of the under teeth, and feeling as if they had become
elongated, (15.) Buccal cavity. Roughness in the buccal cavity, (5.)
Roughness of the buccal cavity of the throat, with sensation of a foreign
body in the throat, and feeling of strangulation. Sensation of heat in
the buccal cavity and throat, (12.) 190. Feeling of dryness in the buccal
cavity as far as the pharynx, (3.) Dryness of the buccal cavity, and
sensation of smarting on the anterior portion of the tongue, as though he
had used pepper, (6.) Great dryness of the buccal cavity in the morn-
ing in bed, (6.) The buccal and pharyngeal cavities feel as if covered
with velvet, which lasts for several hours, (7.) Tongue. Tongue coated
white, (4.) 195. Clean tongue, (24.) Lancinating itching on the left
side of the point of the tongue, and accumulation of saliva in the mouth,
toward noon, (6.) Dry tongue, covered with a yellow fur, on waking, (5.)
Great dryness of the tongue and whole buccal cavity, with much thirst
and desire for cold water, (6.) The tongue is so dry, that in moving it
about, and touching the palate, it makes a noise, (5.) 200. Small vesicle
on the tongue, (1.) Saliva. Increased salivary secretion, (6, 12, 16.)
Increased secretion of saliva, and metallic taste, (12, 13,) Increased sali-
vary secretion and great hunger, which compels him to eat at an un-
accustomed hour, (11.) Increased secretion of saliva, with continual
desire to spit, and metallic taste in the mouth, (12.) 205. Profuse flow
394 Coccus- Cacti.
of saliva, with bitter taste, colic, sensibility of the epigastrium and hypo-
gastriuin, increased by pressure, (12.) Flow of saliva and sensation of
emptiness at the pit of the stomach, (13.) The mouth fills with saliva,
the head aches, and is not relieved by the open air, (16.) Flow of saliva,
followed by pain in the loins and sacrum, (12.)
THROAT. — Palate. Tension and great sensibility of the velum
palati, (5.) 210. Painful tension of the velum, which forces him to
drink often, (5.) Sensation in the velum and upper part of the pharynx,
as if he had eaten food strongly seasoned with pepper, (2.) The velum
is so irritable, that speaking or cleaning the teeth is sufficient to provoke
vomiting, (5.) A pustule of the size of a hemp-seed on the right pillar
of the velum, (3.) Slight redness of the velum with an attack of hoarse-
ness and dryness of the lips, without any effect upon deglutition, (15.)
215. The pain in the velum is sensibly aggravated by speaking and
swallowing, (7.) Uvula. Feeling as if the uvula were elongated, oc-
casioning constant hawking, (12.) Tickling in the uvula, after gargling
with cold water, which provokes a cough, (2.) Tickling in the uvula
which extends over the velum palati, (2.) Tonsils. Swelling of the
right tonsil, (9.) 220. The inflammation of the right tonsil increases on
the second day, (9.) The sore throat increases ; the tonsil is very much
swollen and red, the velum dry ; constant desire to swallow, occasioned
by a foreign body which seems to be seated in the pharynx, (9.)
Eustachian tube. The pressive pain in the Eustachian tube appears
suddenly, an hour before dinner, and disappears while eating warm soup,
(2.) Aching in the right Eustachian tube, aggravated by turning the
head to the right, and when swallowing, (2.) Lancinations in the
palate, and even in the tongue, with dryness causing much thirst, (16.)
Pharynx. 225. The velum palati and pharynx are slightly reddened,
(3.) Scraping feeling in the velum and pharynx every morning on waking,
accompanied by hoarseness, fits of coughing and expectoration of mucus,
which is quieted by tepid gargles, (11.) Roughness of the throat, (5.)
Feeling of roughness in the throat which forces him continually to hawk
up mucus, (3.) Roughness of the throat and expectoration of mucus in
the morning, (18.) 230. Feeling of roughness in the throat, on getting
out of bed in the morning, followed by a paroxysm of coughing," which
lasted half an hour, (17.) Feeling of roughness in the throat," and ex-
pectoration of a fluid mucus at 6 p. m., (17.) Slight burning at the
isthmus faucium, (11.) Slight burning feeling in the throat in the even-
ing, (8.) Violent burning in the throat, a little relieved by drinking cold
water, (8.) 235. Feeling of heat and burning in the pharynx and buc-
cal cavity, (12.) Pressive burning feeling behind the larynx, as if from
a caustic liquid, (7.) He is waked in the morning by a tickling in the
throat, obliging him to sit up in bed, and exciting fits of sonorous cough-
ing, not followed by expectoration, although much mucus had accumu-
lated in the throat, (11.) Tickling in the throat, (20.) Tickling in the
throat which makes him feel like vomiting, (5.) 240. Excoriated feel-
ing in the throat with no effect upon deglutition, (4.) Excoriated
feeling in the throat, (4, 5.) Slight scraping in the throat, (18.) Scrap-
Coccus- Cacti 395
mg feeling in the throat in the morning after a quiet night, frequent
sneezing and some coughing-fits, like the precurrent stage of a cold or
catarrh, (10.) Scraping in the throat, lasting until midday and disap-
pearing after dinner, (5.) 245. Scraping in the throat in the evening,
which forces him to hack, with expectoration of a considerable quantity
of mucus, (10.) Scraping in the throat, and frequent expectoration of
easily-detached mucus, (17.) Scraping, lancination, and constriction of
the throat, (16.) Feeling of pressure in the throat, (8.) Aching in the
throat in the evening, especially on empty deglutition, (18.) 250. Feel-
ing as of a foreign body behind the larynx, (7.) Redness of the fauces
without difficulty in swallowing, (4.) Sensation as of the commence-
ment of inflammation in the throat, (3.) The irritation in the throat
which causes coughing, is seated in the pharyngeal mucous membrane,
only appears in the morning in bed, and disappears after a warm break-
fast, (milk-coffee,) (11.) Dryness of the throat, (5, 9.) 255. Sensation
of dryness on the posterior wall of the pharynx, (9.) Dryness of the
throat as if filled with dust, (5.) Dryness of the throat occasioning
cough, (24.) Dryness of the throat lasting several hours, (17.) Dryness
of the pharynx and posterior nerves during the whole day, with feeling of
a foreign body in the throat, (9.) 260. Dryness of the throat in the
morning, and tension on the right side when swallowing, (7.) Dryness
of the throat in the forenoon, accompanied by accumulation of mucus
about the uvula, (15.) Great dryness of the throat in the afternoon, (5.)
Dryness of the throat in the evening, accompanied by burning in the
velum palati, (5.) The dryness of the throat wakes him several times in
the night ; it is relieved by cold water, (5.) 265. Dryness of the throat
with scraping, which compels him to be often swallowing, (8.) Dryness
of the mucous membrane of the pharynx and nasal cavity, (5.) Very
great accumulation of mucus in the throat, (11.) Great sensitiveness of
the pharynx in the morning, (5.) Increased sensibility of the pharynx, so
that gargling with cold water is sufficient to provoke cough and vomit-
ing of thick, mucous matters, (5.) 270. Feeling as though there
were a hair in the throat which, obliges him to hawk up particles of
mucus, (3.) Sensation as though a thread were hanging in the pharynx,
(14.) The peppery feeling in the pharynx and velum disappears while
gargling with cold water, (2.) The sore throat increased by heat,
and especially in bed, (15.) The sore throat lasts eleven days; in five
minutes after taking lachesis, three globules, 7th dilution, the mucus be-
gan to be easily detached ; the night's rest was good, and in the morning
deglutition was unembarrassed, the redness diminished, and the organs
restored to their normal state, (15.) 275. Catarrhal affection of the pha-
rynx and respiratory apparatus, (5.) The roughness of the throat, cough,
and sneezing last all day, (5.) Burning in the throat when hawking, (8.)
Burning in the throat and lips when smoking, which obliges him to give
it up, (5.) Tension in the velum palati during deglutition, unmoved by
some glasses of wine, (5.) 280. Frequent desire to swallow in the after-
noon, with sensation of a foreign body in the throat, (9.) Dryness of
the organs of deglutition in the evening, (5.) He is obliged to moisten
396 Coccus- Cacti.
the organs of deglutition with cooling drinks, (5.) Difficulty of swallow-
ing in the evening, (3.) Burning pain in the organs of deglutition,
produced by the fumes of tobacco in an atmosphere filled with it, (5.)
285. The organs of deglutition are deeper red than ordinary, and deglu-
tition is more painful, (15.) Scraping in the organs of deglutition, and
constriction of the throat, (29.) Sensitiveness of the organs of degluti-
tion, day and night, (5.) Sensation of a bit of ice sliding along the
organs of deglutition at noon, (15.) It seems to him when swallowing
liquids, as though they were detained in their course by a spasmodic
constriction, (7.) 290. The foreign body in the throat seems at times to
descend into the stomach, at others to rise again ; this lasts all day, (7.)
Burning heat in the oesophagus.
TASTE AND APPETITE.— Taste. Bitter taste, (5.) Bitter taste
during the whole day, (8.) Taste so acrid and bitter, especially at the
root of the tongue, that it makes him feel like vomiting, (18.) 295. Bit-
ter taste in the mouth, and nausea, produced by a scraping in the throat,
after having had a pleasant night, (5.) Bitter, nauseating taste, (5, 6, 12,
22, 14, 24.) Sweetish taste in the mouth, (3.) Continual metallic taste
with hunger, even after having eaten, (12.) Metallic taste limited to the
tip of the tongue, (12.) 300. Nauseating metallic taste, vomiturition,
malaise, and pain in the stomach, (14.) Very disagreeable metallic taste
in the evening when smoking and drinking beer, (12.) Pasty, disagreea-
ble, almost metallic taste, (8, 17, 18.) Disagreeable resinous taste at the
root of the tongue, at noon, after having drunk a glass of water, (18.)
Appetite. Loss of appetite, (4, 7, 8.) 305. Appetite diminished
without disgust for food, and with a feeling as if the stomach were swol-
len, (16.) Want of appetite without disgust for food, (8.) Loss of ap-
petite, with confusion in the head, (5.) Loss of appetite and increased
thirst at noon, (5.) Little appetite, and tongue covered with a white fur
at noon, (7.) 310. Anorexia in the morning, followed by very voracious
hunger, (5.) Capricious appetite, (1.) Good appetite at noon, (5, 12,
24.) Voracious appetite at dinner, (7, 22.) He seats himself at table
with a voracious appetite, but is very soon satiated, (8, 9.) 315. Very
strong appetite, but he has scarcely swallowed a spoonful of soup before
it is gone; he eats without relish, but without aversion, (10.) He sits
down with a good appetite, but does not eat with much relish, and finds
himself rapidly satiated, (11, 17.) Good appetite, and after its gratifi-
cation, pyrosis, (5.) He gets hungry at unusual hours, and is obliged to
eat very often ; but this frequent eating does not strengthen, but only
weakens him, (11.) He is obliged to eat much and often without being
incommoded by this unaccustomed course, (11.) 320. Feeling of hun-
ger even when rising from table, (12.) He eats but little at dinner, in
consequence of having a disgust for food, (17.) Repugnance to eating
any thing, (7.) Coffee is disagreeable to her, and she has an aversion to
water, (16.) Smoking gives him no pleasure, (8.) Thirst. 325. Thirst
not increased, (24.) Absence of thirst, (4.) Thirst, (5.) Thirst in-
creased, especially in the morning, (1.) Increased thirst after dinner, (9.)
330. Violent thirst after dinner, satisfied by cold water ; he feels very
Coccus- Cacti. 397
cold, (3.) Violent thirst in the evening, and great desire to drink
beer, (8.)
STOMACH. — Eructations. Eructations of wind, (10.) Eruc-
tation and desire to vomit, (19.) Daily attacks in the evening of
sonorous eructations, and a pain in the loins exactly corresponding to
the seat of the kidneys, (11.) Nausea. 335. Very great malaise
after dinner, which does not disappear until evening, (12.) Food,
although of easy digestion, causes malaise, pressure at the stomach,
and frequent eructations, which do not afford relief; it is only after re-
peated regurgitations, by which a part of the ingesta are discharged, that
he feels a little better, (11.) Nausea, with insipid, nauseating taste, (13.)
Nausea, eructations, and vomiturition, (18.) Nausea and desire to vomit,(7.)
340. Slight inclination to vomit, disappearing after having drunk some
wine, (5.) Constant desire to vomit, (5.) She thinks for some minutes
that she shall vomit, after which she feels a great heat in her stomach,
which frequently returns for several hours, but never lasts long, (16.)
The thought of cochineal is sufficient to provoke nausea and inclination
to vomit, (5.) Nausea in the pharynx as if his throat were tickled with
a feather, (5.) 345. Nausea and vomiturition, (13.) Something ascends
from the hypogastrium towards the stomach, and nauseates him, (16.)
Vomiturition, salivation, and metallic taste, (12.) Constant vomituri-
tion, (14.) Epigastrium. Sharp prickings in the skin of the epigas-
tric region when uncovering it, (3.) 350. Inflated feeling in the epigastric
region, (15.) Inflation of the stomach by the introduction of food, (7.)
Inflation of the stomach and regurgitation after rising from bed, (7.)
Sensation of heat in the epigastrium and region of the small intestines in
the evening, as though these parts were bathed with warm water, but
without tension or inflation of the abdomen, and directly connected with
the dyspnoea and oppression of the inferior portion of the thorax, (11.)
Epigastrium painful to the touch, (7.) 355. Painful sensibility of the
epigastrium, especially to external pressure, (13.) Slight, undefinable pain
in the epigastrium and left hypochondrium, (1.) Lancinating pain in the
epigastrium during inspiration for five or six minutes ; it disappears dur-
ing expiration, at 4 a.m., on waking, (6.) Pressive pain in the epigas-
trium, (1.) Pressure in the epigastrium, (10.) 360. Burning and pres-
sure in the stomach, (18.) Constriction ascending from the stomach
into the oesophagus, (13.) Transitory pain in the stomach, as if cramp
were about to set in, (13.) Cramp-pain in the stomach, malaise, and
peculiar sensation of cold, which extend the whole length of the stomach
and into the buccal cavity, (11.) The cramp in the stomach recurs, but
is quieted without having recourse to taking food, (11.) 365. Pain in
the stomach and diminution of the pain in the toe, on waking, (7.)
Several attacks of pain in the stomach in the course of the day, with a
disagreeable feeling of violent hunger, (11.) The pain in the stomach,
accompanied by fierce hunger, returns several times, and always lasts for
several days, as well as the frequent discharge of urine ; it is finally ac-
companied with drawing pain in the back, (11.) Pain in the stomach,
with feeling as if there were a large ball there, (14.) Pain in the stomach,
398 Coccus- Cacti.
with remarkably good appetite and constipation, (13.) 370. Lancinations
and griping in the stomach ; this pain leaps like an electric shock to
the genital parts, but soon vanishes, (16.) Dull lancinations, first in the
fundus of the stomach, then in the region of the coecum; two dull lan-
cinations, (12.) Weakness and fatigue of the stomach, (16.) Cold
feeling in the stomach ; it seems to him as if a cool breeze were blowing
in his stomach, (12.) Cold feeling in the stomach, with hunger, tenes-
mus, and pain in the sacro-lumbar region, (12.) 375. Prcssive griping in
the stomach, lasting all day, and which nothing will relieve, (3.) Feel-
ing as if the overloaded stomach was about to empty itself by vomiting,
which, however, does not take place, (7.) Fullness of the stomach, and
constriction all day, (7.) Feels all the morning as if she bad drunk too
much water, (16.) Sensation of a stone in the stomach, and a foreign
body in the throat, (7.) 380. Pressure in the stomach, (b. 15.) Pres-
sure in the stomach after a light repast, (7.) Pressure in the stomach
during the whole day, as if produced by some undigested food, (6.) .Very
violent pressure in the stomach, constriction and sensation of a foreign
body in the throat, continually inducing him to swallow, (7.) Pressure
in the stomach, tearings and lancinations through the whole body, even
in the knee, with weariness and impossibility to take his usual walk, (16.)
385. Pressure in the stomach with constriction in the throat, (7.) Feeling
as if the pressure in the stomach ascended into the pharynx, (7.) Full-
ness and pressure in the stomach through the whole day, (7.) Sensation
of emptiness in the stomach, (13.) Pyrosis. Pyrosis and transitory
shocks in the left inferior canine tooth, when walking and smoking, (7.)
390. Pyrosis and regurgitation of an acrid liquid in the evening, (7.)
Pyrosis for two hours after dinner, (5.) Pyrosis after having taken a
small quantity of wine, (7.) Pyrosis at night, (8.) Pyrosis and painful
tension in the throat in the afternoon, (5.)
ABDOMEN. — 395. Lancinating itching, prolonged into the integu-
ments of the abdomen, as though from leech-bites, in the afternoon, (6.)
Inflation of the abdomen and sensitiveness of the epigastric region, espe-
cially to the touch, (12.) Full feeling in the abdomen, as though he had eaten
too much ; this feeling persists even after having been twice to stool, (7.)
Hypochondrium, right. Lancinating pain in the right hypochon-
drium, extending from the edge of the false rib to the right side of the
back, aggravated by the pressure of the hand upon the parts, and ame-
liorated by the discharge of flatulence, (6.) Crackling in the abdomen
below the right false ribs, (6.) Hypochondrium, left. 400. Pain
in the left hypochondrium, as if from incarcerated flatulence, (24.) The
pains commence in the left hypochondrium, and extend to the left dorsal
and lumbar regions, (24.) He is waked by a burning in the region of
the left hypochondrium, which is quieted by the application of the warm
hand, and he goes to sleep again, (11.) Burning drawing in the splenic
region, which ascends into the thorax, does not last loner, but returns
several times, (11.) Paroxysms of acute, transitory lancinations in the
splenic region, (15.) 405. Lancinations in the spleen, at first acute, then
dull, changing into obtuse sensations in the left hypochondrium, (11.)
Coccus- Cacti. 399
Rapid lancinations in the left hypochondrium, ascending iuto the left
thorax, (11.) Drawing lancinations, extending from the left hypochon-
drium along the left hip, and lasting several seconds, (6.) Umbilical.
Pain around the navel, extending from time to time towards the iliac
bones and their symphisis, (1.) Digging pain around the navel, (2.)
410. Violent colic accompanied by headache, (14.) Borborygmi with
pains in the loins and sacrum, (12.) Borborygmi and discharge of copious
flatus, (18.) Painless gurgling in the abdomen after dinner, but very
disagreeable from its long duration and violence, (18.) The borborygmi
ceased after the discharge of flatus, when walking about the room, (11.)
415. The same gurgling during the siesta, which annoys him a great
deal, and compels him to abandon his accustomed nap, (11.) Borborygmi
again during the whole day, removed by the emission of flatus, (1 1.) A
great deal of flatulence, which sometimes rolls about in the bowels, at
others is very easily discharged, (24.) Accumulated flatulency in the
abdomen, some hours after dinner, accompanied by heat in the stomach,
(16.) Flatulence with great general malaise in the afternoon, (9.) 420.
Slight colic with fruitless desire to go to stool in the afternoon, (12.)
Violent, but transitory griping colic after dinner, (10.) Almost constant,
but mild colic in the afternoon, commencing in the stomach and extending
towards the region of the ccecum, remitting from time to time, and then
returning, (12.) Moderate colic in the morning on waking, followed by
efforts to vomit, with nausea and copious salivation, metallic taste, pain in
the stomach, and flatulency, (12.) Colic in the morning, followed by
a diarrhoea, which is repeated three times during the day, (5.) 425.
Violent colic in the morning on waking, but ceasing after a stool, (12.)
Colic around the navel, followed by a soft stool at 1 1 a.m., and several
times in the course of the afternoon, (7.) Colic and diarrhoea, towards
noon, (5.) Colic, followed by diarrhoea and chills in the evening, (5.)
Cutting colic in the abdomen, (5, 17.) 430. Cuttings around the navel
at 4 a.m., soon after waking ; she is afraid to move, for fear of aggravat-
ing the pain, which lasts a quarter of an hour, (4.) Hypogastrium.
Colic in the hypogastric region, ameliorated by the emission of flatulence,
(6.) Pains in the hypogastrium and sacrum during dinner, (16.) The
sensitiveness of the epigastrium extends throughout the abdomen ; lan-
cinating drawing and pressive pains especially appear in the groins and
vesical regions, which oblige her to keep her bed, (13.) The pains in the
abdomen, after having lasted an hour, extend towards the hypogastrium ;
they are not like the menstrual molimina, but lancinating pains, (16.)
455. Rumbling movement in the hypogastrium, followed by very acute
lancinations, as if from needles, extending from the bladder through the
urethra, toward the glans ; they come on again several times within three
minutes, when seated, (3.) Twisting pain deep in the abdomen on the
left side of the vertebral column, as if in the kidney and ureter, (24.)
Inguinal. Agitation and lancinations in the left groin in the morning,
(15.) Pruritus, itching, and drawings in the region of the groin and
pubes, in the prepuce, glans, dorsum of the foot and toes, (12.)
cc
400 Coccus- Cacti.
STOOL. — Rectum. Sudden feeling of distension and laneinations in
the rectum, on the cessation of which a beat extends through the whole
hvpogastrium, (16.) 440. Lancinating pain in the rectum, lasting several
hours, diminishing from time to time, but always aggravated by walk-
ing, (16.) Violent jerking and boring laneinations in the rectum in the
afternoon, when seated ; they are suddenly transferred to the neck of the
bladder, follow the direction of the ureter as far as the kidneys, and
vanish, (15.) Usual stool followed by burning in the rectum, (15.)
Lancinating pain in the rectum during stool, (16.) Anus. Secretion of
a fluid in the sulcus and at the anus, which stains the sheets yellow, (18.)
445. Exceedingly violent lancinating thrust from the anus through the ure-
thra at 5 p.m., (1*7.) Slight formication at the anus, (18.) Pretty severe
itching at the anus, (9.) Stool. Tenesmus and copious diarrhoea in the
evening, (12.) Anal tenesmus after a short walk at noon, (18.) 450.
Pressing desire to go to stool soon after having eaten, with tenesmus,
slight burning, protrusion of hemorrhoidal tumors, and discharge
of matters enveloped in mucus, (11.) Copious discharge of flatus, (18.)
Very irregular stools, sometimes hard, sometimes liquid, sometimes two a
day, and sometimes a day without one, (24.) Irregular stools during the
whole proving. Stool with tenesmus ; fseces like potter's clay, and after
the passage a very disagreeable transitory cramp-pain in the rectum,
opposite the inferior extremity of the sacrum, (9.) 455. Frequent fruit-
less desire to go to stool, (12.) Frequent fruitless desire to go to stool,
during the day, and when the evacuation comes on, the pains in the
loins and sacrum vanish, (12.) Constipation for four days, (8.) The
usual 8 o'clock a.m. stool does not take place until -2 p.m., and is then
straining and slimy, (9.) Desire to go to stool, followed by an evacuation
of hard substances, (13.) 460. Evacuation of a hard ball, followed by
a pappy stool, (9.) Hard stool, (7.) Consistent but unsatisfactory stool
in the forenoon ; very copious evacuation an hour after dinner, (noon,)
not fetid, with discharge of much flatus, which relieves him, (8.) Three
soft stools during the day, mixed with round, solid matters, (7.) Pressing
desire for stool on getting out of bed, followed by a pappy evacuation,
and accompanied by much flatus, (6.) 465. Three soft stools, (12.)
Two diarrhceic stools, (13.) Very hard stools, (13.) Several copious
soft stools, (12.) Two copious stools on waking, (12.) 470. Daily stools, co-
pious and pappy, (3.) Copious evacuation, contrary to his usual habit, (7.)
URINE. — Bladder. Alternations of cramps, coldness, and heat in
the bladder, (16.) Pain in the bladder during the night, and fruitless
desire to urinate, (24.) Excoriated, sore pain in the bladder, (2.) 475.
Sensation of fullness and tension in the bladder, without desire to urinate,
(5.) Sensation of fullness in the abdomen, especially in the vesical re-
gion, (12.) Pressure in the_ vesical region, with discharge of mucus
from the vagina, (13.) She is obliged to make water very often after
dinner, which, together with a pressure analogous to that which is expe-
rienced at the period, makes her think her bladder is diseased, (16.)
Feeling of pressure and fullness in the bladder, extending toward the
Coccus- Cacti. 401
urethra, with constant desire to urinate, and frequent discharge of nor-
mally-colored and slightly acid urine, (3.) 480. Attack of pressure,
tenesmus, and cutting pains in the bladder, during which the face becomes
red, (24.) The pressure and pain in the bladder continue, even after the
evacuation of the urine, (24.) Tenesmus of the cervix-vesica3, (2.) Strong
vesical tenesmus for making water, (24.) The tension in the bladder
remains even after the discharge of the urine, (5.) 485. Very violent
twisting pain in the neck of the bladder at 1 P.M., lasting a quarter of
an hour, and not ameliorated by the discharge of urine or of flatus, (17.)
Urethra. Burning in the urethra when urinating, (24.) Slight burn-
ing in the urethra when urinating at noon, (18.) The burning of the
urethra continues, even after having urinated, (10.) The burning in the
urethra and the titillation in the meatus cease after the discharge of
clear, straw-colored urine ; the sensation returns, however, several times
in the day before urinating, (8.) 490. The burning in the urethra and
swelling of the vulva continue for fifteen days, (16.) Very violent lanci-
nating thrusts in the anterior portion of the urethra and glans, a long
time after having urinated, when in bed at night ; they force him to
groan and cry out, and last a minute and a half, (5.) The pains in the
uropoetic organs are more violent, especially the pain in the urethra when
urinating ; it is burning, and accompanied by a sensation as if a little
stone were sliding along the urethra, (10.) Sensation in the anterior
part of the urethra, twice before urinating, as if he were pricked with a
blunted needle, (8.) Very violent lancinations along the urethra toward
the glans, lasting several minutes, after the discharge of a deeper colored
urine, (3.) 495. Transitory lancinations in the urethra toward the glans,
two hours after having urinated, (3.) Painful drawing in the left side
of the urethra, (24.) The meatus is so contracted and constricted that
the urine flows very slowly, and as the vulva is excoriated, the burning
is very violent, and lasts an hour, (16.) Pruritus in the meatus, (8.)
Violent pruritus in the orifice of the urethra, (24.) 500. Pruritus and
itching in the meatus, obliging him to rub it constantly, (11.) The titil-
lation at the meatus comes on as yesterday, but the urine is less copious,
cloudy, and yellow, (8.) Urine. Discbarge of pale urine in a stronger
jet, (17.) Irresistible desire to urinate; the urine was excreted in very
great quantity and in a very powerful jet, (10.) Copious uriuation in
a very powerful stream, three times between 5 and 7 P.M., (17.)
505. The urine, in issuing from the urethra of a female, does not form
the usual jet, but runs down over the surrounding parts, (16.) Desire
to make water several times during the day, (3, 10.) Frequent desire
to urinate in the afternoon, (13.) Frequent desire to urinate, followed
by discharge of very copious urine, sometimes with pain in the urethra;
frequent emission of a clear and copious urine during the whole day, (3.)
510. Very frequent and copious discharge of pale urine, (17.) Very
frequent discharge of urine, almost every hour in the afternoon, (17.)
Frequent, but scanty discharge of urine, (3.) Very frequent emission of
urine, (3, 8.) He woke twice from a desire to urinate ; but the emission
402 Coccus- Cacti.
is difficult, slow in coming, and takes place with straining, (tenesmus of
the bladder or cervix,) (20, 24.) 515. Night much disturbed by fre-
quent discharges of urine, (11.) He is obliged, contrary to his usual
custom, to rise and urinate during the night, (11.) Diminution of urine,
(17.) The quantity of urine is diminished one half, (24.) Nocturnal
excretion of urine diminished, (18.) 520. He commonly makes water
eight times a day ; the number is reduced to six during the proving, (24.)
Exceedingly scanty urination at night, (18.) Violent desire to urinate;
the urine excreted exceeds the quantity of fluid ingesta, (10.) Increased
urinary excretion, (12.) Very much increased urinary excretion, (11.)
525. Urine at first normal in color ; it then becomes citron-yellow,
brown, and finally red, (24.) Frequent emission of a highly loaded
urine, (15.) Frequent emission of pale urine, (3.) He is obliged to
urinate almost every hour; urine pale, aqueous, rnd inodorous, (11.)
Copious discharge of pale, watery urine, (3.) 530. Frequent emission
of a deep-colored urine, (2.) Urine excessively loaded, (15.) The urine
becomes cloudy, and, during the last days of the proving, jumentous,
(18.) Evacuation of a copious watery urine, of an alkaline smell, almost
every hour, (11.) Scanty and infrequent urine, of an ammoniacal odor
and very high color, (11.) 535. The quantity of urine is not increased,
but it is deeper colored, cloudy, and has a cadaverous odor, (15.) The
urine seems thicker and hotter than usual, when passing it at 9 P.M., (3.)
Frequent and copious emission of pale urine, which seemed to be thicker
than ordinary, like oil, (3.) Increased acidity of the urine, (24.) The
urine is so acrid that it burns in passing ; she perceives this burning to
increase for several days, (16.) 540. The urine contains mucus in the
form of filaments, clouds, and flocks, (18.) The urinary sediment is en-
tangled in much mucus, (18.) The urine contains neither albumen, pus,
nor blood, (24.) Excretion of urine, which deposits a lateritious sedi-
ment, (23.) The urine deposits a reddish sediment, of the color of brick-
dust, which adheres to the vessel, (6.)
GENITAL. — Male. 545. Pruritus in the prepuce and meatus audi-
torius internus, (15.) Lancinating itching in the prepuce, (6.) Pruritus
and itching on the prepuce and glans, (12.) Dull throbbing in the glans
during the whole day, and, from time to time, tickling in the urethra,
(15.) Pruritus around the glans, (24.) 550. Sensation of disagreeable
heat in the glans and left testicle, (17.) A suppurating pimple on the
middle of the penis, (18.) The pimple on the penis discharges a fluid
on being squeezed, (18.) Violent pruritus on the scrotum in the morn-
ing after having quitted the bed, (9.) Drawings and transitory lancina-
tions in the right testicle, which ascend toward the inguinal ring, (3.)
555. Extraordinary lasciviousness, (3.) Lasciviousness without erection,
(5.) Excitement of the venereal appetite, (10, 15, 17, 18.) Very great
sexual appetite on getting up, (8, 18.) Excessively violent sexual desire
during the day, and voluptuous dreams during the following night, (10.)
560. Venereal appetite excited the first four days, afterward depressed
(11.) Diminished sexual appetite and yet a nocturnal pollution, (12.)
Coccus- Cacti. 403
Pollution in the morning, (12, 17.) Moderate erection in the morning,
with great lasciviousness, (5.) Great desire to urinate in the morning,
with erection aud longing for coitus, (5.) 565. Very frequent erections
day and night, (24.) Erection and pollution toward morning, (9.)
Erections in the morning which last longer than usual, (9.) Female.
Sensation when walking as though the lips of the vulva were swollen,
(10.) Pain in the vulva when going to bed so violent as to make her
shed tears ; she is obliged to sit up in bed, and goes to sleep in that posi-
tion, (1G.) 570. ^ The swelling of the genital parts increases, but it is
less troublesome in walking, because it is displaced toward the anterior
part of the vulva, (16.) The excoriated feeling at the vulva is very
violent in consequence of a continuous discharge of mucus, (16.) The
vulvar tumor increases, becomes hard, and is sensitive to the touch, (16.)
Throbbing and burning sensation in the vulvar tumor, and excoriated
feeling when walking, (16.) The night is restless, but she is not waked
by the vulvar pains, which do not come on until she has made water
the next morning, (16.) 575. The tumor of the vulva diminishes, but
on the other hand, the' urine is discharged with difficulty, slowly and
with burning pains, accompanied by lancinating thrusts in the excoriated
portion, (10.) The menses appear three days too soon, (as they some-
times do,) but they are more than usually copious, (16.) The menses
are three days too early, are more free, and the blood is black and thick,
(13.) The menses are seven days too early; the blood very abundant,
black, and thick, (13.) She feels a sensation on the fifth day of the
catamenia, analagous to that which she sometimes perceives at their
commencement ; tension and constriction in the hypogastrium and some-
thing ascending to the stomach, which makes her think she shall vomit
water, (16.) 580. Discharge of a liquid which has not the density of
leucorrhcea, (16.) Discharge of mucus from the vagina, preceded
by drawing and thrusting pains in the inguinal, vesical, and pubic
regions, (15.)
LARYNX. — Rough feeling in the larynx all day ; his voice after a
long silence is hoarse, but it becomes clearer by talking, (8.) Rough
feeling in the larynx when speaking and after having spoken, (3.) Pain
and rough feeling in the larynx after a short conversation, (3.) 585. Tick-
ling in the larynx, followed by. hacking, (12.) Lancinations in the larynx
from time to time, and hoarse voice, (15.) The scraping and dry feeling
in the larynx are increased toward evening, and accompanied by hack-
ing cough and hawking, (1.) Scraping in the larynx and trachea, with
slight hoarseness in the evening, (23.) Scraping in the larynx causing
cough, (23.) 590. Sensation of swelling in the larynx, with difficulty of
speaking, (3.) Irritation in the larynx obliging him to cough, (5.)
Acute prickings in the larynx, (3.) Scraping in the trachea toward
evening, obliging him to cough, by which a copious amount of mucus is
brought up in the shape of globules, (10.) Roughness in the trachea
provoking a frequent cough, (7.) 595. Hoarseness. Hoarseness, (45.)
Hoarseness sometimes greater, sometimes less, (1.) Persistent hoarseness,
404 Coccus- Cacti.
(18.) Hoarseness all day, (7.) Hoarseness in the morning, (3.) GOO. The
hoarseness and scraping are never entirely absent, except in bed, where
the heat produces a quieting effect, (11.) Hoarseness and scraping in
the velum palati toward evening, (15.) The hoarseness and cough re-
main for several days ; the expectoration increases, becomes grumous and
grayish, (7.) Hoarse voice in the morning, with mucus in the throat,
which obliges him to hawk, bringing up every time a little thick mucus,
(8.) Constant hoarseness, with mucous expectoration, (8.) 605. Slight
hoarseness and scraping in the throat, in the evening, (15.) Hoarseness
and pressure on the chest, (2.) Voice constantly veiled, (8.) Veiled
voice, deeper than natural, (3.) Weariness of the vocal organs ; she
becomes hoarse after a short conversation, and her respiration is a little
embarrassed, (18.) 610. Fatigue of the vocal organs from speaking a
little too long, (18.) His breath seems hotter to him than usual, with
hot feeling in the chest, (7.) Warm breath, (3.) Cough. Frequent
desire to cough and sneeze during the whole day, (5.) Short cough, (2.)
615. Short, dry cough, (4.) Short cough in the morning, with expecto-
ration of thick mucus, (18.) Infrequent cough during the morning,
some isolated coughs, (8.) Cough excited by a tickling in the larynx,
which hinders sleep, (5.) He is inclined to cough, from a constant irri-
tation in the trachea and larynx, which renders the velun* so sensitive
that swallowing food and saliva becomes very troublesome ; these symp-
toms aggravated by beer, (7.) 620. Very violent cough, which, not-
withstanding the expectoration of mucus, is constantly excited by a tick-
ling in the neighborhood of the bifurcation of the trachea; the attacks
go on increasing, (8.) Feeling of mucus ascending and descending in
the trachea, causing tickling and cough, (8.) Fatiguing, painful cough
on waking, caused by a tickling in the larynx, (18.) Attack of short
cough, produced by a tickling in the larynx, in the forenoon, (18.) Dry
cough in the morning, which lasts several minutes, and finally causes a
vomiting of mucus, (5.) 625. The cough annoys him all day, and at 3
r. m., an hour after dinner, it is so violent as to vomit him, (8.) The
cough is so violent as to cause vomiting, and the expectoration of a great
quantity of thick, viscous, and albuminous mucus, (17.) Before he vom-
its from the violence of the cough, he endeavors in vain to quiet it by
drinking a glass of cold water ; but after having vomited, a second glass
has the effect, (8.) Dry cough at intervals, (23.) Dry cough, (1, 19.)
630. Constant dry cough in the morning, (5.) Violent cough without
expectoration, which lasts a long time in the morning, (5.) Alternations
of dry and moist cough, (18.) Moist cough, small quantities of mucus
are detached, (1.) Frequent cough, with expectoration of mucus, (17,
18.) 635. Frequent cough, with scanty expectoration during the day,
(8.) Frequent expectoration of mucus after coughing during the whole
day. (17.) The cough in the ewniug is accompanied by a much more
copious expectoration of greenish mucus, tasting like licorice, (7.) Less
frequent cough, with easy expectoration of a yellowish-white mucus
mingled with saliva, (8.) Cough with expectoration of a yellowish mucus,
Coccus-Cacti. 405
accompanied by sneezings, (5.) 640. A little greenish-yellow mucus
tasting like licorice, is detached by the cough, (7.) Paroxysm of short
cough, with expectoration of globular mucus, (15.) Cough, with expec-
toration of globular mucus, (5.) Periodical attacks of cough and ex-
pectoration of mucus in the morning, (8.) Paroxysm of coughing
produced by a tickling in the larynx and throat, (24.) 645. Paroxysm
of coughing for half an hour, and expectoration of a great quantity of
mucus, (15.) Attack of tickling at 7 p. m., producing a five-minute
paroxysm of coughing, ending by an expectoration of mucus, (17.) Every
attack of coughing is followed by a burning sensation lasting some time,
(7.) Frequent hacking and hawking, with increase of thirst, (1.) Slight
coughing in the morning, with expectoration of gray and globular mucus,
(11.) 650. Cough in the morning, with easy mucous expectoration
mixed with viscid filaments, (8.) Cough, which wakes him at 6 a. m.,
having remissions of a minute; it is at first clear, dry,* and barking;
subsequently some thick mucus is detached, and the effort of doing this
causes desire to vomit, accompanied by an excoriated feeling in the throat
and pressive headache, (8.) The cough wakes him at 1 a. m., in conse-
quence of which and the burning, excoriating paiu in the lungs, and
pressive headache, he cannot go to sleep again ; he does not sleep, ex-
cept from 6 to 7 A. m., (7.) Frequent nocturnal cough, with expectora-
tion, (7.) Dry cough wakes him twice in the night, (8.) 655. The cough
is aggravated by the heat of the room, and diminished by staying in an
un warmed room, (17.) The paroxysm of coughing is renewed by the
heat of the bed, # (8.) He can scarcely speak for coughing in a warm
room, (8.) He does not cough in the open air, although the tempera-
ture is cold, but the cough comes on as soon as he enters a warm room,
(8.) The cough is ameliorated by gargling with cool water and swallow-
ing a portion, which very much diminishes the heat of the throat ; the
cough afterward returns on driuking warm milk, but less violent, (8.)
660. Cleaning the teeth produces violent coughing, and, in consequence,
vomiting of a liquid mucus, (5.) Tobacco-smoke, to which he is accustom-
ed, excites cough, (5.) Expectoration. Frequent spitting of mucus,
(5.) Copious and easy spitting of mucus in the afternoon, (12.) Great
abundance of mucus in the respiratory organs, (10.) 665. Expectora-
tion of a very thick mucus, (18.) Increased, sweetish, thick expectora-
tion, (7.) Easy expectoration of pretty copious mucus, (1.) Frequent
and easy expectoration of whitish mucus of the size of a pea, (3.) Ex-
pectoration of globular mucus, (18.) 670. After slight efforts of hawk-
ing, expectoration of a yellow globular mucus, (10.) Expectoration of
a viscid mucus in the morning, (18.) Expectoration of easily detached
mucus in the afternoon, (17.) Easy mucous expectoration in the morn-
ing, (18.) Expectoration of a great quantity of grayish mucu
675. Expectoration of yellow mucus of an acid taste, (12.) Expectora-
tion of a yellowish mucus, inclining to red, and of a bitter-sweet taste,
(12.) Expectoration of a nauseating mucus, (12.)
CHEST.— Lancinating itching in the skin in the region of the right
406 Coccus- Cacti.
nipple, (6.) Lancinating itching in the skin of the pectoralis major and
right groin, (6.) 630. Lancinating itching in the skin of the right cla-
vicular region. Drawing pain in the right clavicular region, aggravated
when lying on that side, (6.) Several rapid lancinations between the
sixth and seventh ribs, first on the right, then on the left side, (12.) Acute
stitches in the right half of the chest, when seated in the afternoon, along
the sternum, and soon after some coughing with easy expectoration of
globular, gelatinous, grayish mucus, (15.) Rapid lancinations in the
region of the left nipple in the morning, after waking from a sound sleep ;
they soon disappear, and never return, (2.) 685. Violent, penetrating
pains near the left nipple in the afternoon, and dull lancinations between
the shoulders, extending in a radiating way towards the anterior part of
the thorax, (15.) He wakes at 4 a.m. with a bruised pain in the left
clavicular region, (6.) The bruised pain in the left clavicular region
continues aggravated by moving the left arm, and terminates, when lying
on the left side, in a strained pain, (6.) Transitory lancinations in the left
clavicular region in the forenoon, (15.) Bruised pain in the region of
the left clavicle, which seems dislocated during the movement of the
head or left arm, or when lying on the left shoulder, (6.) 690. Tensive
pain in the upper left side of the chest, near the clavicle, more severe in
the daytime ; it lasts several days, and is aggravated by moving the left
arm, (15.) Acute, penetrating lancinations, followed by ulcerative pain
in the upper part of the left chest, repeated for several clays, several times
a day, (1.) Lancinations in the left half of the chest, brought on or
aggravated by fast walking, (15.) Lancinating pain in the left side of
the thorax, and in a very circumscribed region, aggravated by walking,
but not by a deep inspiration, (3.) Not very painful lancination in the
middle of the first left false rib, coming on when walking in the street,
and ceasing when sitting still in the room, (3.) 695. Pain in the left
side of the thorax, extending toward the sternum, with pressive pain on
the chest, (4.) Lancinations and itchings on the edge of the left false
rib, deep between the stomach and the hypochondrium, (6.) Lancinating
pain, short and very circumscribed, on the edges of the cardiac region,
which on pressure resembles that which would be produced by an ab-
scess, (6.) . Burning and slight lancinations between the fifth and seventh
ribs, first on the left, then on the right side, (12.) Frequently an acute
lancination on the left side, between the fifth and seventh ribs, which dis
appears on a deep inspiration, and comes on immediately on expiring, (12.)
*700. Lancinations in the region of greatest curvature of the last left false
rib, coming on when conversing, aggravated by walking and going up
stairs, but not at all by a deep inspiration ; ameliorated by rest, (4.)
Dull pressure in the region of greatest curvature of the fifth and seventh
ribs, repeated several times during the day, (15.) Several lancinations at
the left vertebro-sternal angle of the last rib on the left side, rapidly re-
peated, (4.) Excoriated feeling at the apex of the left lung, with sensa-
tion of pulsation always alternating, with a contraction in the lower lip,
(spasm of the orbiculorris,) (7.) Heat deep in the thorax ; occasionally
Coccus- Cacti. 407
burning, especially in the region of the heart, (7.) 705. Transitory
burning under the sternum in the forenoon, (18.) Excoriating and pres-
sive pain below the sternum after the noon lunch, (18.) Painful pressure
in the middle of the sternum in the forenoon, from before backward ; at
the same time an analogous pain between the scapula?, from behind for-
wards, lasting but a little while, (15.) Pressure and burning below the
xyphoid cartilage for a quarter of an hour, (18.) Sensation of pressure
on the middle of the sternum, extending into the two scapula?, (4.)
710. Sharp prickings in the integuments of the chest, (3.) Throbbings
like strong pulsations, sometimes near the heart, at others in the middle
of the chest, and again at the apex of the lungs, (7.) The throbbing in
the chest becomes infrequent, and is succeeded by oppression and a sen-
sation as if the thoracic cavity were too narrow; this lasts till evening,
and is followed by chills and nocturnal perspiration, which relieve it, (7.)
Throbbing feeling in the lungs, (7.) The feeling of heat in the chest
disappears in a quarter of an hour, and is succeeded by a feeling of ten-
sion and pressure, and by pulsations at the apex of the lungs, (7.) 715.
Sensation of heat in the lungs when walking, lasting half an hour, and
disappearing suddenly, (7.) Sensation of heat during a long walk, in
the chest, epigastrium, and thigh, accompanied by formications in the skin
of the thigh, (7.) Heat in the interior of the chest, especially in the
region of the heart, and in the inferior half of the thoracic cavity, (7.)
'Excoriated feeling at the apex of the lungs, accompanied by short-lived
chills, notwithstanding the high temperature of the air, and followed by
moderate headache, increased by walking, (7.) The excoriated pain in
the chest is by turns dully lancinating, and seems to be seated in the
pleura? and pericardium; he sometimes feels it in the deep regions of the
lungs and heart, and it seems to him that the pulsations of the heart,
which accompany it, are stronger, (7.) 720. Excoriated pain in the chest
below the clavicles, and very great fatigue of the respiratory passages, (10.)
Paroxysms of excoriated pain and oppression in the whole chest, lasting
an hour, and returning several times during the day, (15.) The ex-
coriated and burning pain in the chest continues ; it is accompanied by
cough and hoarseness, (7.) The cough becomes harder in the evening,
and very painful from the excoriated and burning pain in the chest,
which follows it, (7.) The excoriated pain in the chest diminishes, as
the expectoration becomes easier, (7.) 725. The pains in the chest gra-
dually increase; the excoriated pain becomes burning, and frequently
changes its position ; it, nevertheless, most frequently affects the heart
and the apex of the lungs, with necessity for deep respiration and cough, (7.)
Feeling of weariness in the lungs, accompanied by lancinations in the
middle of the sternum, which disappears after breakfast, consisting of
burnt barley-coffee, (3.) Lancinations in the lower part of the thorax, (3.)
Several rapid lancinations in the inferior part of the left chest in the morn-
ing, when walking in the street ; they recur in the evening, (3.) Dull
lancinating thrust in the right inferior pulminary lobe at 4 p.m., when
breathing deeply, (17.) "730. Transitory painful lancinations in the
408 Coccus- Cacti.
thoracic cavity, sometimes on the right, sometimes on the left side, with
oppression and dryness of the throat, (22.) Pressive and lancinating pain,
which seems to be seated in the right inferior lobe of the lungs, when
getting out of bed in the morning; it is particularly severe when in-
spiring deeply, but is not affected by motion ; sneezing is impossible on
account of the pain, which remains until noon, and then suddenly dis-
appears. Pressing, weak and bruised feeling in the chest, (3.) Violent
pressure on the chest in the evening, followed by an ulcerative pain
about the heart, (15.) Pressive and cramp-like pain in the middle of
the chest, (3.) 735. Pressive and fatigued feeling in the chest, (3.)
Transitory rheumatic pain in the tendinous aponeuroses of -the two fore-
arms, and subsequently in the legs also, (18.) Pressure in the chest in
the evening, accumulation of mucus in the air-passages, and almost un-
conquerable somnolence, (10.) Sensation of pressure on the chest, and
increased sensibility around the left nipple, (2.) Difficulty of breathing
in the afternoon, which increases toward evening, accompanied by pa
roxysms and lancinations in the upper part of the left chest, (15.)
740. Transitory oppression of the chest, followed by great moral exhila-
ration, (12.) Her breathing is a little more difficult than usual when
walking, (16.) Oppressed respiration on getting up, (18.) Difficult re-
spiration, oppression, (18.) Deep inspiration, and yawnings involuntarily
performed, when walking, relieve, (7.) Heart. 745. Palpitation for
several minutes, causing anxiety^ (12.) Pulsations of the heart accele-
rated, irregular, and productive of anxiety, after dinner, (6.) The move-
ments of the heart are irregular, at times very tumultuous, at others very
labored, (11.) Tumultuous movement of the heart when lying down
after dinner, and isochronous throbbings in the ear ; radial pulse, accele-
rated, tremulous, (11.) Palpitations during the night, like those of the
evening, but less, and accompanied by pressive pain in the heart, (10.)
750. He is waked during the night by a violent palpitation, which lasts
a quarter of an hour ; the back, sacral and coccygeal regions are bathed
in sweat, (10.) Very violent palpitations, lasting twenty-five to thirty
seconds, during a half sleep at midnight, as if from a terrible fright ;
they shook the whole body, and returned in gradually decreasing
strength, (6.) The throbbings in the thorax are composed of five or six
consecutive strokes, intermitting for five or ten minutes, and then re-
appearing in a different place, (7.) Violent chills and a hacking cough,
excited by a rough feeling in the trachea, accompany the palpitations,
while writing at 10 a.m., and are attended by confusion in the head, and
increased nasal secretion, (7.) Sensation of a very accelerated arterial
' throbbing on the surface of the heart, recurring several times when walking
(7.) 755. The pulsation in the heart alternates with the prickings in the
thigh, and with a feeling in the lower lip, as if it were drawn out, (7.)
Throbbing pain in the heart, and from time to time pulsations on the surface
of the heart, (7.) Transitory lancinations between the sixth and seventh ribs
first on the left side, then on the right, (12.) Dull lancinations through
the heart, with throbbings which he thinks he can hear, but which are
Coccus- Cacti 409
not confirmed by placing the hand on the spot, (7.) The pains in the
heart and pericardium coincide with a pressive, tensive pain, sometimes
in the stump of the left shoulder, sometimes in the joints of the left
fingers and coxo-femoral articulation ; it is never very severe, but is fre-
quently repeated, and disappears towards evening, (7.) 760. Painful-
ness in the heart from morning till noon, (7.) The pain in the heart is
felt during the day also, (10.) Indefinable pain in the heart, frequently
interrupted by a pulsation, (7.) Digging and pressive pain in the region
of the heart, appearing in the evening when riding in a carriage, and
only ceases when he leaves the vehicle, (10.) Pressure in the cardiac
and renal regions, (10.) 765. Feeling of an afflux of blood to the heart, (7.)
BACK. — Nape. Pressive pain in the nape, between the second and
third cervical vertebra, in the evening, (9.) Violent tension of the left
cervical muscles on waking, disappearing on getting up, (18.) Lancina-
tions in the muscles of the left side of the nape, when turning the head, (1.)
Drawing and tearing here and there, especially in the neck, between the
shoulders and on the forearms, (18.) 770. Lancinating pain in the
muscles of the nape, (1.) Back. A very small pimple on the back,
which discharges a great deal of thick pus, (18.) Pressure between the
scapulae, descending by degrees towards the sacrum, and becoming per-
manent in the renal region, accomjmnied by frequent paroxysms of op-
pression of the chest for six days, (15.) Lancinations in the region of the
left scapula, extending to the olecranon, and aggravated by moving the
arm, (4.) Lancinations in the scapulae for two days, (4.) 775. Weak
lancinating pain in both scapulae several times in the day, (2.) Rheu-
matic pain in the scapula and sacrum, (5.) Violent rheumatic pain, ex-
tending from the right scapula over the anterior and external surface of
the humerus, during rest at noon, (6.) Loins. Pressive pain in the
renal region, extending by degrees to the bladder and its sphincter, ac-
companied by vesical tenesmus and frequent emissions of deep-colored
urine, (2.) 780. The pain in the kidneys, accompanied by increased
urinary secretion, lasts six or seven days, (11.) Dull pain in the renal
region, (11.) Lancinating and boring pain in the region corresponding
to the kidneys, in the evening in bed, lasting several seconds, (6.) Sud-
den, acute, prolonged lancinations, extending from the left renal region,
along the ureters into the bladder, (15.) Pressive pain in the renal re-
gion, (15.) 785. Attacks of nephritic colic, but seldom, and not violent,
(10.) Slight attacks of nephritic colic, urine very copious, and dull
pain in the urethra, (10.) He jumps about, bends himself, and rubs his
hypogastrium in order to relieve the spasmodic pain in the kidneys, and
obtains some relief after some minutes, with discharge of much flatus, (10.)
Excessively violent pain in the renal region seizes him suddenly when
sitting quietly in the afternoon ; it radiates from the two sides of the
kidneys, and differs from the pressive and drawing pain previously felt
there, by its spasmodic character and extension, and can only be com-
pared to the pain experienced in the testicle in consequence of a bruise,
(10.) The pressive pain in the kidneys is more violent than the pre-
410 Coccus- Cacti.
ceding evening, and is alternated with the drawing pain, which extends
through the ureters into the bladder; the latter is relieved by the dis-
charge of flatulence, (10.) "790. Dull pressure in both kidneys during
the whole day, especially in the right, aggravated by movements of the
trunk, and by external pressure; it disappears in the evening, (10.) He
wakes at 5 a.m., and can go to sleep no more ; a drawing pain commences
in the right kidney, and extends along the course of the ureters, as far as
the bladder ; at the same time a single lancinating thrust, and continual
pressure in the urethra, in the navicular region, (10.) Slight pains in the
sacrolumbar region, (12.) Bruised pain in the sacrolumbal- and iliac re-
gions, on waking, (6.) Bruised pain in the sacrolumbar region, in the morn-
ing, (6.) 795. Bruised pain in the left lumbar region, (6.) Pains in the
lumbar vertebras in the evening, increasing in intensity at night, (5.)
Drawing pains in the sacrolumbar region, (12.) Tension and drawing,
extending from the loins toward the rectum, (12.) Tension in the sacro-
lumbar muscles, (18.) 800. Violent pressure and drawing pain in the
sacrolumbar region during the evening, (18.) Pain in the loins and sa-
crum in the evening, (12.) Two lancinating thrusts, beginning in the lum-
bar region and ending in the region of the ccecum, (12.) Pain in the loins
and sacrum, in the evening, (13.) Sacrum. Pain in the sacrum, (5.)
805. Pressure in the sacral region, extending downwards and forwards to-
wards the bladder, and lasting a quarter of an hour, (15.) Pain in the sa-
crum, lasting all the morning ; it intermits for some time, and then reap-
pears, (18.) Violent pain in the sacrum, and pains in the hypogastrium
for several hours in the afternoon, with a transitory feeling as though
there were ulcerated spots there, (16.)
UPPER EXTREMITIES.— Shoulders. Cold feeling in the skin of
the right shoulder, and dorsal surface of the same side, (1.) Weight and
pressure in the right shoulder and along the lateral posterior side of the
body, (11.) 810. Weight and tension across the shoulders and nape,
which seems to be connected with the pains in the region of the spleen,
(11.) Tension, drawing and tearing in the right shoulder and axilla, (12.)
The pain in the left shoulder prevents his lying on the right side ; it is re-
lieved by lying on the affected side, and burying himself well in the bed,
(1 1.) Slight drawing in the left shoulder, changing into weight, and in the
evening into painful paralysis, such as is experienced when a part of the
body in perspiration is exposed to a very strong breeze, (11.) Drawing
and tearing in the right shoulder during the day, extending into the
forearm and index, (12.) 815. The pain in the shoulder extends in the
evening into the forearm, and becomes at times very violent, (5.)
Arms. Slight rheumatic pain in the humerocubital joint, (2.) Dis-
agreeable drawing in the right deltoid in the evening, rendering the mo-
tions of the arm painful, especially that of raising it. (11.) Lancinating
and rheumatic pain in the internal fleshy part of the left humerus, lasting
but a little while, (6.) Transitory rheumatic pain in the external side of
the right humerus, in the evening in bed, (6.) 820. Painful drawing in
the muscles of the right arm, (6.) Drawing rheumatic pain along the
Coccus- Cacti. 411
anterior surface of the humeral muscles during rest, (6.) Elbow. He
wakes in the night with a pain in the olecranon and humerocubital arti-
culation, which prevents his going to sleep again, (11.) Violent pressive
pain in the neighborhood of the elbow-joint, at noon, (6.) Pain in the
muscles in the bend of the elbow, (6.) 825. Lancination as from the
bite of a leech in the bend of the left elbow, (6.) Violent lancination in
the left olecranon and right patella, (6.) Forearm. Transitory tearing
in the tendinous aponeuroses of the two forearms, in the forenoon ; when
it disappears, an analogous one appears in the legs, but soon vanishes, (18.)
Hands. Painful drawings in the metacarpal bone of the right thumb,
in the morning in bed, (C.) Paralytic pain in the joint of the right
hand during the morning, (17.) 830. Lancinating itching on the back
of the right hand, (6.) Fingers. Moving the thumb and compressing
cause a very acute pain, (7.) The left thumb is swollen, and its move-
ments embarrassed, (7.) Transitory rheumatic pain in the right little
finger, and left great toe, during motion, (7.)
LOWER EXTREMITIES. — Nates. Lancinating rheumatic pain
along the sciatic nerve, when at rest, descending from the left nates along
the posterior and external surface of the thigh, (6.) 835. Sensitiveness
of the tuberosity of the ischium to external pressure, and when remaining
a long while seated, (1.) Thighs. Bruised pain in the thigh behind the
great trochanter, appearing in the evening, lasting but a little while, re-
appearing and disappearing when walking, (9.) Great lassitude and
weariness of the lower limbs, especially manifest in the calves, (11.)
Itching in the lower limbs, forcing him to scratch, (9.) The bruised pain
and painful lassitude of the lower limbs is in connection with the pain in
the kidneys, and the increased urinary secretion, (11.) 840. Great weari-
ness of the lower limbs in the afternoon, as long as he remains seated,
but which disappears as soon as he goes out, (17.) Great fatigue of the
lower limbs, and burning in the soles of the feet, after a short walk, (18.)
The pains in the hip-joints and ischiatic tuberosities are very persistent, (1.)
Lancinating, rheumatic pain in the hip-joint, particularly violent when
rising from his seat, and from sudden motions, (1.) Painfulness of the
thighs in the evening, as if after a long walk, (8.) 845. Drawing pain in
the upper and external part of the left thigh, (6.) Rheumatic lancination
along the internal muscles of the thigh in the heat of the bed, (6.) Sud-
den drawing along the anterior surface of the thigh above the knee-joint,
in the right great toe and left thumb, at 8.30 p.m., (17.) Transitory
rheumatic pain on the internal and anterior surface of the right thigh, in
the morning in bed, (1.) Painfulness of both thighs along the track
of the great vessels and nerves, (1.) 850. Pricking on the anterior sur-
face of the thighs, analogous to the sensation experienced on drawing elec-
tric sparks from the body, (7.) The heat in the thorax, especially in the
cardiac region and the arterial pulsation on the heart reappear when the
prickings in the thighs cease, (7.) The pricking in the thighs causes the
thoracic symptoms to disappear, (7.) Formication on the anterior portion
of the thighs in the afternoon, when walking, as if a hot stream were run-
412 Coccus- Cacti.
ning over the skin; lasts ten minutes. Knees. Both knees and toes
swollen and hot, after a long walk ; the pain is pressive, entirely prevent-
ing motion, and though he was otherwise well, confining him to his bed, (7.)
855. Slight rheumatic pain in the knee-joint, (2.) A sudden lancinating
and tensive pain in the bend of the left knee, in the afternoon when
walking, so that he cannot extend his leg, and for several minutes he can
scarcely walk, (15.) Dull lancinations in the poplileal region, extending
along the left tendo Achillis, the dorsum of the right foot, then between
the shoulders and the upper part of the left chest, where they do not re-
main more than an instant or two, (15.) Pain in the right patella, during
a long walk, especially at its internal edge, increased by pressure and
motion ; in the evening he cannot move, (7.) Pressive pain in the left
patella, (C.) 860. Violent lancinating thrust in the right patella, in the
evening, as if from an electric spark, (6.) Violent lancination in the edge
of the left patella, as if produced by an electric spark, (6.) Leg's. Great
burning and itching on the left leg, (18.) Itching on the legs, forcing him
to scratch, (17.) Itching on the legs and left fingers, in the afternoon, (17.)
865. Attacks of momentary burning in the legs, (18.) Feeling of ex-
coriation on the right tibia, (18.) Access of throbbing lancination in
both legs ; the pain suddenly disappears, and comes on in the upper part
of the left chest, (15.) Lancinating and tearing pains, rather severe in
the internal part of the right tibia, at noon, and slight burning at the
anus, (18.) Weakness of the legs, in the evening, (15.) 870. Great
weariness after a very short walk, and pain in the whole right leg, (18.)
Grating pain in the bone of the tibia and olecranon, (18.) A pain in the
lower half of the left tibia, which rises and descends, when quietly seated
in the morning, (2.) Cramp-like drawing pain in the right calf, (1.)
Rheumatic lancination along the muscles of the calf, (6.) 875. Cramp-
like drawing in the calf, frequently returning, (1.) The cramp-like pains
in the calves, shoulder, foot, and elsewhere, frequently return, and with
varying strength, (1.) Itching on the legs above the malleoli, rising as
high as the knees, towards noon, and returning in the evening to its first
position ; it lasts several days, and constantly increases, (9.) Transitory
lancinations in the right leg, not far from the ancle, after dinner, (18.)
Some pimples around the malleoli, (6.) 880. Violent lancinations in the
right internal malleolus, (G.) Several sudden lancinations in the right
internal malleolus, in the morning in bed, (G.) He cmnot extend
his foot without increasing the pain in the tendo Achillis, (8.) Crack-
ling felt when placing the fingers upon the tendo Achillis when extending
and flexing the foot, perceived for two days past, (8.) Going up stairs
renders the tendo Achillis very painful, (8.) 885. The pain in the tendo
Achillis becomes so_ violent, that he is obliged to keep his room ; nothing
can be seen, but it is a little sensitive to the touch, (8.) The pain in the
tendo Achillis is aggravated by walking on the pavement in the street ;
he is obliged to limp ; the foot is turned outwards, and he is obliged to
stop from time to time to ease the pain, (8.) The pain in the tendo
Achillis is seated, an inch above its insertion into the calcaneum, and is
Coccus- Cadi. 413
not accompanied by any perceptible external change of appearance ; the
tendon can be pulled and squeezed without pain, which is only felt when
walking and extending the leg, (8.) Pressive drawing pain in the left
tendo Achillis, only when walking or extending the leg, (8.) The pain in
the tendo Achillis lasts ten days, (8.) Feet. 890. Pain as if from a sprain
on the internal surface of the calcaneum, and in and around the ancles,'
when flexing the foot, (12.) Feeling of swelling in the articular surface
of the tarsus, which impedes motion, (7.) Very violent sprained pain on
flexing the feet, (12.) The left foot is painful when walking, (7.) Great
weariness of the feet, and burning in the soles, after a very short walk, (18.)
895. Little lancinating shocks in the left sole, near the toes, (6.) Violent
pain in the soles, when seated, especially in the anterior part, most of the
time burning, and progressively diminishing until it disappears, (18.)
Pruritus, itching, and drawing in and, between the toes, (12.) Cramp in
the right toes, (1.) Pressive pain in the great toe during a loflg walk, which
increases to such an extent, that in the evening he cannot put his foot to
the ground; he feels cold all over, which lasts some time in bed, (7.)
900. Acute prickings in the evening, sometimes under the nail of the
right great toe, sometimes in the ends of the fingers, beneath the nails of
the thumb and right index, (0.) Intolerable itching in the crease on the
inferior surface of the left great toe, at noon, (6.) Prickings as though
caused by fragments of glass, on the inferior surface and point of the left
toe, (6.) Cramp in the last three toes of the right foot, when lying
down, (1.) Very violent pain, in the forenoon, in a corn of the little
right toe, which forces him to limp in walking, (18.)
SKIN. 905. Pimples on the forehead, sternum, and end of the nose,
which dry up rapidly in two days, (9.) Two other pimples appear on
the right side of the sternum, and one on the point of the nose, besides
the two on the forehead of the day before, (9.) Disagreeable itching in
different parts of the skin, (3.) Lancinating itching in various parts
of the skin, (6.) . Lancinating itching in the skin, even in the scalp, in
the evening in bed, (6.) 910. Lancinations and very frequent itchings in
different parts of the skin, the scalp, the external ears, the right side of
the neck and nape, on the edges of the rami of the lower jaw, in the
neighborhood of the nipples, on the back, pit of the stomach, in the ax-
illary cavity, and bends of the groin; they disappear on getting out of
the warm bed, (6.) Itching on the skin of the back and abdomen, and
especially on the extensor side of the limbs, (1.) Acute lancinations in
different" parts of the body, especially in the glans, integuments of the
abdomen, and of the head, (15.) Red spots and itching pimples in
various parts of the body, (1.)
SLEEP. — Yawning-. Desire to yawn and stretch the limbs, (pandi-
culation,) with tensive pain in the sacrum, (5.) 915. Inclination to
yawning and stretching, (4.) Sleep. Somnolence during the day, (5.)
Somnolence, weariness, and drawing pains in the limbs in the afternoon,
(16.) Almost insurmountable drowsiness after dinner; he can scarcely
keep himself awake; followed by great depression, (10.) Great drowsi-
414 Coccus- Cacti.
ness in the evening, (5.) 920. He goes to bed with his head greatly
confused, and a general sensation of great debility, after having eagerly
drunk a glass of beer, but cannot go to sleep before midnight, (8.) The
feeling of painful paralysis, and the constrictive pain in the scalp, com-
pel him to go to bed earlier than usual, where he experiences increased
general heat, during which he goes to sleep, (11.) Excellent sleep dur-
ing the whole proving, (12.) Quiet sleep, (1.) Quiet sleep in the morn-
ing, (5.) 925. Sound, but not refreshing sleep, (18.) Troubled sleep,
restless night, (4.) Sleep disturbed by pain, (24.) Sleep disturbed by
dreams, (9.) Sleep disturbed by vivid dreams ; he wakes at 3 a.m. in a
great agitation, with general dry heat ; sleep interrupted the rest of the
night; in the morning general perspiration, and his pulse descends from
a hundred to its normal rate, (lY.) 930. Sleep disturbed by dreams,
and great dryness, with scraping in the throat, especially on the velum
palati, (1.) Sleep disturbed by frequent waking, in consequence of vivid,
disagreeable dreams, (1*7.) Sleep agitated the whole night, in conse-
quence of a disappointment he had met with, (5.) Agitated sleep with
sexual excitement, but without a sufficient erection, (5.) Sleep very agi-
tated, full of dreamings ; he cannot get to sleep again before 4 a.m., (11 .)
935. Very disturbed night, sleeplessness, and feeling as if the whole body
were swollen, (5.) Very agitated night ; the external heat prevents him
from sleeping, (7.) Night somewhat agitated and disturbed by a gurg-
ling in the bowels, which is specially perceived when he lies on his right
side, (11.) The first of the night good, but on waking, the mucous mem-
brane of the buccal cavity and pharynx is dry, the tongue stiff and hot;
he is in a hurry to drink cold waier to moisten these parts, (5.) Sleep dis-
turbed by shocks in a carious tooth, (1.) 940. Sleep interrupted by
cough, (7.) He does not go to sleep until midnight ; verv much dis-
turbed, and the least thing wakes him with a start and palpitation, (6.)
Agitated sleep, troubled by a dry cough, (5.) After waking at midnight,
it takes him an hour and a half to go to sleep again, (9.) Agitated
night, he wakes at 4 a.m., (11.) 945. Drowsiness in the morning, dis-
turbed by shocks in a carious right molar, (1.) Desire to sleep longer
in the morning, (5.) Groaning in the night when asleep, (18.)
Dreams. Numerous dreams, (6.) Dreams of disappointment, (6.)
950. Voluptuous dreams, (5.) Dreams of love-affairs and youthful pas-
sion, (3.) Very voluptuous dreams with pollution, a phenomenon ex-
tremely rare with him, (15.) Vivid dreams of platonic love, which he
remembers, (15.) Vivid dream about syphilitic diseases, (6.) 955. Dreams
that ke is in company, and is afraid he shall fail in the etiquette and
usages of society, (9.) Dreams of a great many people, and of anxiety
to place some one in safety, (9.) Dreams of a great many people, palaces,
churches, and love-affairs, followed by a weak pollution, (9.) Dreams
which he forgets, (1.) Numerous dreams, but he cannot remember
them, (9.) Waking. 960. Frequent waking in the night, with over-
excitement, as if he had drunk very strong coffee, (7.) He wakes very
early, and is very drowsy, (1.) Frequent waking in the night, with para-
Coccus-Cacti. 415
lytic feeling in both thighs and in the left shoulder ; afterwards pressure
and dull lancination in the middle of the arm, with general heat, followed
by perspiration, after which he sleeps again, (15.) He is waked at night
at 12.30, by a tickling in the larynx, followed by a paroxysm of cough-
ing for ten minutes, with expectoration of a great quantity of thick mu-
cus; he cannot go to sleep under an hour, (17.) He wakes at 4 a.m.,
without any perceptible cause, and soon afterwards perceives a slight
lancination under the left great toe, (6.) 965. She wakes two days in
succession at 4 a.m., (4.) He wakes very early, (1, 5.) He wakes earlier
in the morning than ordinary, (1, 15.) He wakes early in the morning
at 6 a.m., with burning heatlong urethra, and an almost insupportable
tickling in the meatus urinarius, (8.) He wakes at G a.m., and cannot
go to sleep again, (9.) 9*70. He only sleeps six hours every night during
the whole proving, (11.) He wakes in the morning earlier than usual,
with a great feeling of malaise, (11.) He wakes at 5 a.m., contrary to
his usual habit, remains some time wide awake, and then sleeps a^ain
until 7 a.m., (18.) He sleeps well, but is waked early by an oppression
of the chest, which disappears after a hot breakfast, but appears agan
soon afterwards, and inconveniences him from time to time for several
days, (15.) Restless night, and on waking, headache, which is soon dis-
sipated, (16.) 975. Headache, hoarseness, and roughness in the throat,
on waking, (7.) His headache is better on waking at 7 a.m., but the
affection of the chest continues unabated, (7.) He is waked by colic,
followed by a diarrhoea, which relieves the colic, (12.) General depres-
sion when he awakes, (4.)
FEVER. — Coldness. Paroxysm of universal chilliness, (9.) 980.
Frequent chills, (5.) Chills over the whole body, in the evening, (4.)
Chills which run along the whole length of the spine, (1.) More or less
chilliness during the day, moderately accelerated pulse, (17.) Chilliness
between 3 and 5 p.m., cuttings in the hypogastrium, and discharge of
much inodorous flatulence, (17.) 985. Chilliness, which lasts several
hours after dinner, (17.) Chill after dinner, which descends from the
shoulders along the arms, with a sensation as if the skin were about to
separate from the flesh ; this is repeated several times, but ceases during
exercise in the open air, (9.) Chills over the whole body at 8 P.M.,
especially along the back, with thirst, (7.) Chilliness, accompanied by
cough and sneezing, in the evening, (5.) Horripilations, which run over
the whole body for half an hour, at 9 p.m. ; pulse 100, (17.) 990. Horri-
pilation, with heat in the head before going to bed, lasting for half an
hour in bed, followed by general dry heat and sweat, which continues
all night, and affords much relief; urine red, more scanty than usual, (7.)
Feeling of extraordinary coldness, without chills. Transitory coldness
runs over the limbs, followed by pressure at the stomach, (16.) Coldness
during the whole day; she does not feel the heat of 25° Reau., (88°
Fahr.,) (4.) He wakes in the morning with cold feeling in the feet and
upper part of the body, (17.) 995. Increased coldness and thirst in the
afternoon, (17.) Coldness with umbilical colic all the afternoon, followed
416 Coccus- Cacti.
by soft stools, (7.) General coldness in the evening, with lancinations
and palpitations of the heart, and excoriated feeling in the middle of the
chest, (7.) The ordinary covering is not enough to keep him warm in
bed, (7.) Heat. Skin hot and dry, at night, (5.) 1000. Feeling of
general increased h e at in the evening in bed, (7.) Universal heat in the
bed, (7.) Sweat. No sweat even, at night, (4.) Copious general per-
spiration in the morning, (7.) Slight moisture on the legs and feet in
the morning, (11.) 1005. Sweat on the right leg, (18.) Violent sweat
and general debility during a long walk. Fever. Slight febrile move-
ment in the evening, (5.) Dry heat in the head, in the evening in bed,
red face, and the rest of the body cold ; by degrees the dry heat becomes
general, lasts until midnight, and is followed by sweat on the upper part
of the body only, which lasts until 5 a.m. ; sleep disturbed and inter-
rupted by pressive and throbbing headache, and by the pulsations of the
heart, (7.) On the morning following the feverish night, the tongue is
coated white, dry, as if it were excoriated, and the headache continues, (7.)
Pulse* 1010. Pulse accelerated, 76 per minute, (4.) Great excitement
of the circulation in the morning on waking ; the arteries throb so power-
fully, that he thinks he can hear them, (7.)
GENERAL. — Sensation of throbbings through the whole body, (7.)
Great excitement, which does not cease even in the open air ; it seems to
him as if the arteries were throbbing more forcibly, with sensation of
general heat. This state lasted for an hour after dinner, and disappeared
when walking, (7.) Agitation and physical anxiety, (5.) 1015. Agita-
tion and constant shivering, (5.) Great agitation during the whole day, (5.)
inexpressible agitation ; notwithstanding the foul weather, he is obliged
to seek the open air, when his agitation is quieted, (5.) Very great
physical prostration ; she cannot remember ever to have felt the like, (4.)
General prostration, compelling him to keep his bed, (14.) 1020. De-
bility of the limbs during the day, head feels empty, and nose obstructed,
(5.) Weariness, prostration, and great irritability after a short nap, (10.)
Very great fatigue from the atmospheric temperature, which nevertheless
is not very high, (18.) Great fatigue after a short walk, and painfulness
of the right leg, (18.) Great fatigue and somnolence during the morn-
ing, (5.) 1025. Great fatigue and much yawning in the evening, (24.)
She is fatigued, prostrated, and indisposed to labor during the whole day,
(11.) He feels debilitated and fatigued after leaving the bed in the morn-
ing, and he cannot decide to do anything until after he has swallowed
his coffee, (11.) Weariness so overpowering, that she is obliged to seat
herself several times during a short walk, with headache, (4.) Painful
lassitude of the limbs during the day, (5.) 1030. Drawing rheumatic
lancinations, as if from splinters imbedded, coming on in the evening
in the bed, on the slightest muscular effort ; they appear, for example, in
the arm from holding a book in the hand, (6.) Lancinating rheumatic
pain in different muscles, (1.) Tearing in the long bones, (18.) Alter-
nations of fatigue, and pains in the limbs, (16.) Great facility and light-
ness of all the voluntary motions, (4.) 1035. Voice hoarse, heat of the
Coccus- Cacti 417
body increased, drawing in the leg and calves, great fatigue in the calves,
and general feeling in the body as if it were stuffed. On touching any
part of the body, at night, it seemed to him enlarged, (5.) Coma vigil
at night ; it seems to him as if his body had attained the enormous size
of a bale of wool, (5.) The temperature of an apartment moderately
warm, seems to him on entering it, insufferably hot, (3.) The headache
and pains in the chest are assuaged by the movement of the carriage,
but the cough remains, (7.) Characteristics. 1040. In general, the
mucus in the throat, and the flatulency, are the most tenacious attendants
among the effects of cochineal, (10.) The duration of the effects of
cochineal does not correspond with their intensity, that is to say, even
the violent symptoms produced by it do not last any great length of time,
(11.) Lachesis mitigates the symptoms of cochineal.
JUST PUBLISHED
BY
WM. KADDE, 322 BKOADWAY, NEW-YORK.
Guernsey's Homoeopathic Domestic Practice. With full de-
scriptions of the dose to each single case. Containing also Chapters on Anatomy, Physi-
ology, Hygiene, and an Abridged Materia Medica. 1854. Third thousand. Bound, $1.50.
l^* Dr. Guernsey's book of Domestic Practice is a reliable and useful work. It is espe-
cially adapted to the service of well-educated heads of families. — John F. Gray, M.D.
Hahneman (Dr. Samuel). — The Lesser Writings of, collected
and translated by E. E. Dudgeon, M.D. With a Preface and Notes by E. E. Marcv, M.D.
With a beautiful steel engraving of Hahnemann, from the statue by Steinhaeuser. Bound,
one large volume (784 pages.) $3.
S3F" This valuable work contains a large number of Essays of great interest to laymen as
well as medical men, upon diet, the prevention of diseases, ventilation of dwellings, <tc. As
many of these papers were written before the discovery of the Homoeopathic theory of cure,
the reader will be enabled to peruse in this volume the ideas of a gigantic intellect, when
directed to subjects of general and practical interest.
" The Lesser Writings must be read by every student of Homoeopathy who wishes to be-
come acquainted with the il/asrer-mind."— R. E. Dudgeon, M.D.
Hahnemann (Dr. Samuel). — Materia Medica Pura. Translated
by C. J. Hempel, M.D. 4 vols. Bound, $6.
Hahnemann (Dr. Samuel). — The Chronic Diseases, their Specific
Nature and Homoeopathic Treatment. Translated and edited by C. J. Hempel, M.D. Willi
a Preface by C.Hering, M.D. , Philadelphia. 5 vols. Bound, $7.
Hahnemann (Dr. Samuel). — Organon of Homoeopathic Medi-
cine. Third American edition, with improvements and additions from the last German
edition, and Dr, C. Hering's Introductory Remarks. Bound, $1.
J3P" The above four works of Dr. Samuel Hahnemann are, and will for ever be, the greatest
treasures of Homoeopathy ; they are the most necessary works for Homoeopathic Prac-
titioners, and should grace the library of every Homoeopathic Physician.
Hartmann (Dr. F).— Acute and Chronic Diseases, and their Ho-
moeopathic Treatment. Third German edition, revised and considerably enlarged by the
author. Translated, with additions, and adapted to the use of the American profession
by C. J. Hempel, M.D. 4 vols. $5.75.
Hartmann (Dr. F).— Diseases of Children, and their Homoeopa-
thic Treatment. Translated, with notes, and prepared for the use of the American am!
English Profession, by Charles J. Hempel, M.D. 1853. Bound, $2.
Jahr (Dr. G-. H. G).— Diseases of the Skin ; or, Alphabetical
Repertory of the Skin-Symptoms and External Alterations of Substance: together with
Ihe morbid phenomena observed in the glandular, osseous, mucous, and circulatory- m
terns, arranged with pathological remarks on the diseases of the skin Edited hv Pi
Hempel, M.D. 1850. Bound, $1. . lM °? c - J
Jahr's (Dr. G. H. G.) and Possart's New Manual of the Ho-
meopathic Materia Medica, arranged with reference to well-authenticated observation* »i
the sick bed, and accompanied by an Alphabetical Repertory, to facilitate and sernrp th
selection of a suitable remedy in any given case. Fourth edition, enlarged bv the Antw
Symptomatology and Repertory. Translated and edited by C. J. Uemnel m n iT'
Hound, S3. 50. ' ' '' M - u - 18o »-
Douglas (Dr. J. S).— Homoeopathic Treatment of Intermittent
Fevers. 1853. 38 cts. luiitttjUI,
Humphreys (Prof. Dr. F).— The Cholera and its Homoeopathic
Treatment. Bound, 38 cts. ^ mL
'•;■
\=>
6-- ^
"frr
'''\
\
Live Music Archive
Librivox Free Audio
Metropolitan Museum
Cleveland Museum of Art
Internet Arcade
Console Living Room
Books to Borrow
Open Library
TV News
Understanding 9/11